company directory - spri · red biotech companies are mainly ... broadens to include venture...
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Company directory
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A brief look at biosciences companiesin the Basque Country, 2006 Bioscience is turning into a fast growing sector within the
Basque economy, underpinned by the growth trend in
company creation, the science and technology base and
the innovation system, and supported by the BioBasque2010 Strategy, the first specific strategy designed to
develop a business sector related to biosciences in Spain.
Since the strategy was initiated in 2002, the Basque
administrations have supported the creation of companies
and the R&D activities both in the academic and business
worlds, launched initiatives for the attraction of talent
and training issues, created a bioincubator that adds to
the array of Business Incubator Centres already existing,
and reinforced the scientific base by establishing 2 new
world-class Cooperative Research Centres in the biosciences
field, -CIC bioGUNE (biomedicine and biotechnology) and
CIC biomaGUNE (biomaterials and nanobiotechnology).
The proactive governmental stance, a favourable business
environment, the funding of industry-academy
collaborations, and the cooperation between
entrepreneurs, scientists and interface organisations have
resulted in the creation of a biocluster with a steady flow
of new entrants. Since the beginning of the strategy, a
new company is created every 3 months (4-5 companies
per year, for a population of about 2 million inhabitants).
In 2008, the biocluster was composed of some 71
companies which represent around 1.500 direct jobs and
have a global turnover nearing 305Mc. These figures do
not include companies that analyse or use biological
systems (molecular, micro or cellular level) as a tool for
their activities, unless the company also performs R&D.
Thus, the actual numbers of employees and total revenue
related to biosciences are considerably larger, and
estimated to be at least five-fold.
Compared with the previous year, the number of
employees, the revenues, and the profitability have
increased. Further good news is that the number of
companies where this growth is observed is also on the
increase, confirming a positive trend across the sector.
The youth of the sector is one of its main features, reflected
by the fact that 46% of the companies have been created
after 2004. The biocluster is also defined by the strong
intensity in R&D activities and R&D employment, reporting
a level of business expenditure far superior to the public
Administration.
This is a young and emergent sector, which includes
companies with long product development processes,
and start-ups that are taking up operations this same year.
Hence, the sector cannot demonstrate yet its full impact
in economic terms. In fact, the significance of the biocluster,
the prospects and its economic weight will become more
apparent in the coming years, when the start-ups evolve
and more products under development are marketed.
Nº companies 71
Total Employment 1.500
R&D Employment 380
Turnover (Mc) 304
% women 55%
% companies < 5 years 46%
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Business diversity and structure
The global data are somewhat lopsided as the biosciencearena is heterogeneous and, in fact, two main groups ofcompanies can be identified within the biocluster, withdifferent business dynamics and variables.
Some 20 companies are suppliers with very little R&Dperformed in the Basque Country, whereas the remaining50-odd companies, so-called biocompanies, constitutethe nucleus of the growing sector.
The suppliers group includes companies that providereagents and products for research, equipment, lab design,etc. Many of them are subsidiaries of multinationals and,globally, they present a very stable situation, with hardlyany new entrants. Nevertheless, the growth trend in thebusiness sector and in the scientific world has impactedpositively in their financial results, particularly in thecompanies with local headquarters.
The biocompanies constitute a more heterogeneous group,and they are the true nucleus of the sector, where theemployment, turnover, and R&D investment areconcentrated. The biocompanies, in fact, are responsiblefor 87% of the total turnover, 83% of the employment,and 98% of the R&D activities (Investment andEmployment). And this is also the group where most ofthe growth is taking place.
57% of these companies have reported increased revenues,40% have incorporated highly qualified personnel, and32% have invested more resources in R&D activities.
0
Turnover EmploymentR&D
InvestmentR&D
Employment
Biocompanies
10
20
30
40
50
60
70
80
90
100
83 %87 % 98 % 98 %
Suppliers
Biocompanies
Biomaterials
Biotechs
Others
Pharma
Suppliers/Distributors
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Despite the diversity within the biocluster, there is a strongpreponderance of companies active in the healthcare area,whereas the agro-food and the industrial fields have alesser presence.
Healthcare registers the biggest number of companies,as well as of employment and revenues. Several companiescover different stages in the biopharmaceutical valuechain, from drug discovery, screening and validation, toproduct development, clinical assays andcommercialisation. Red biotech companies are mainlyfocused in the discovery phase, aimed at the search ofbiomarkers for diagnostics and as possible therapeutictargets. Some of these companies lead niche fields ofPersonalised Medicine and Preventive Medicine in Spain.Other companies develop new chemical entities, offer invivo High Content Screening, produce biomolecules withtherapeutic activities, or provide contract research andmanufacturing expertise.
An additional group of companies are active in the fieldsof Regenerativa Medicine, Biomaterials and Orthopaedics,developing implants of different materials, prostheses,cells and tissues. Some are also investigating newapplications that derive from nanobiotechnology, includingdrug delivery.
Regarding the Knowledge Based BioEconomy (KBBE),some companies use industrial biotechnology approachesto commercialise products or processes for a great varietyof sectors, including the agro-food and beverages, cosmetic,chemical, and environment.
Diagnostic or detection systems are also competitiveniches for food safety, environment, veterinary medicineand human health. An increasing number of companiesare developing different types of biosensors and relatedequipment, supported by the bioRegion expertise inmanufacturing, engineering and converging technologies.
Start-ups, the engine of the biocluster
In terms of structure and age, the biocluster includes bothconsolidated, long-established companies (such as thetwo main pharma) and agile biotech start-ups,biomaterial/implant companies, bioproducers andspecialised service providers.
Although the main economic impact derives still fromcompanies created before 2001, the changing scenario ismainly due to the new companies that continue to emergeat a steady flow. The origin of the start-ups is diverse. Amajor part of them originates from entrepreneurs andfrom the private sector. Corporate organisations, inparticular industrial groups or companies with moretraditional activities, are diversifying throughout spin-outs, or co-investing in start-ups.
63 % Human health
20 % Animal health and agrofood
14 % Industry and environment
3 % Others
21 % Technology Centres
8 % Medical
38 % University & Research Centres
33% Private Sector & Entrepreneurs
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Another significant proportion of the start-ups have theirroots in the University and Research Centres, demonstratingthe capacity of the scientific base, the entrepreneurialmindset and the supportive environment for technologytransfer. The start-ups from Technology Centres also showa growth trend, particularly in the last two years.
Human capital is an essential asset in these companies,knowledge and R&D intensive, and the start-ups show adifferential trait regarding gender: parity is observedthroughout most companies and across nearly allprofessional levels. The presence of women is particularlysignificant at the managerial and entrepreneurial levels(40%).
Nearly all of the start-ups are located in one of thebioRegion Technology Parks, which also house businessincubators (including a specific bioincubator, BIOKABI),research centres, university groups and hospitals.
Financing is not a bottleneck for the launch of the start-ups. In addition to private investment (FFF type) andinstitutional support, the companies have access to equity(seed capital), of public or semi-public origin. As thecompanies mature, the array of financing instrumentsbroadens to include venture capital, business angels andpension funds, which can be found in at least 15% of thecompanies.
The emergent biocluster is experiencing the evolutionthat corresponds to a growing sector, with high rates ofcompany creation and increasing figures of revenues,employees and capitalisation. However, it is alsoundergoing processes that are a first indication of amaturing sector.
Both the commitment of long-established companies and,significantly, the creation of the first bio corporateorganisations are contributing to consolidate the biocluster.
BioBasque Company Directory
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The Basque bioRegion Company Directory listscompanies that develop or produce applicationsderiving from the use of biotechnology and convergingtechnologies and disciplines, and companies thateither produce or commercialise services and productsneeded for the research, development and productionactivities of those applications.
The Company Directory provides a brief portray ofthe companies, based on their own description ofactivities. The first part of the guide presentsbiocompanies related to human health andbiomedicine, including pharmaceutical companiesand CROs, biomaterials and medical devices,veterinary and agro-food, diagnostics, industrial andenvironmental biotechnology, and specialised services.In the second part, the guide offers contactinformation on suppliers and distributors.
For more information and updates, please visitwww.biobasque.org
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Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Environment and Industry,Environmental Applications (biocleaning, bioremediation, purification, etc.), Chemistry.
Company profileTechnology-based company dedicated to the development and production of biological productsformulated with enzymes and micro-organisms, for bioremediation and biodetergence applications.A&B Laboratorios de Biotecnología combines biotechnology and clean technologies for the developmentof its innovating products under life cycle analysis for the industrial and agro-food sectors, and forenvironmental institutions. The organisation develops its products in a management system backedby AENOR certification of the systems of quality, environment, R&D&I, and Ecodesign, under ISO andUNE standards.
Key wordsEnvironmental biotechnology, bioremediation, biodetergency, LCA, ecolabel.
5 5-50 50
A&B LABORATORIOS DE BIOTECNOLOGÍA
Address:Polígono Industrial de JúndizPaduleta esquina Júndiz01015 Vitoria · ÁlavaSpainContact person:Jon Kepa IzaguirreTelephone:+ 34 945291616Fax:+ 34 945292939E-mail:[email protected]:www.ab-laboratorios.comFounding year:2001Employees:28Annual turnover (millionc)
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5 5-50 50
Address:Parque Tecnológico de BizkaiaEdificio 801-B · 2ª planta48160 Derio · BizkaiaSpainContact person:Ainara HernandoTelephone:+ 34 944048080Fax:+ 34 944048081E-mail:[email protected] year:2006Employees:14Annual turnover (millionc)
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Reagents and raw materialsuppliers.Human Health (Infectious diseases, Cardiovascular diseases, Central Nervous System, Oncology,Metabolism, Dermatology, Regeneration, Respiratory disorders, Allergy, inflammation, Autoimmunediseases, Haematology, Hepatology, Obstetrics, Gynaecology, Andrology, Nephrology and dialysis).
Company profileAbyntek Biopharma S.L. is a privately owned biotechnology company that centres its activity indeveloping, producing and commercialising antigens and antibodies. Abyntek relies on its team oftrained postdoctoral researchers to guarantee optimal technical support and who will remain in closecontact with the customer as part of the high quality service provided. A strong investment in RDIconstitutes one of the fundamental values on which the business strategy of Abyntek is based. TheRDI activities of Abyntek focus on two main areas:1.The development of new technologies to produce monoclonal antibodies.2.The development of diagnostic and prognostic products, as well as products to predict the response
to treatment and for the treatment of lung diseases.Abyntek is an integral part of the Progenika Biopharma S.A. and Proteomika S.L. group of companies.
Key wordsAntibody, antigen, mouse monoclonal, rabbit polyclonal, custom antibody, antibody catalogue,recombinant antigen, peptide synthesis, immunisation, fusion, screening, cloning, isotyping, asciticfluid, purification, IgG, yeast, bacteria, protein, lung diseases.
ABYNTEK BIOPHARMA
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Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation. Human Health, Ophthalmology.
Company profileAJL OPHTHALMIC is the only company dedicated to manufacture intraocular lenses at national level.Our company has a commitment to R&D activities for the development of new medical devices whichcontribute to improvements in the sanitary field.AJL has ISO 9001 and CE 0318, to be able to launch competitive, safe and high quality products.
Key wordsMedical devices, ophthalmology, clean rooms, R&D.
5 5-50 50
Address:Parque Tecnológico de ÁlavaEdificio E-301510 Miñano · ÁlavaSpainContact person:Eva Larra MateosTelephone:+ 34 945298256Fax:+ 34 945298209E-mail:[email protected]:www.ajlsa.comFounding year:1992Employees:36Annual turnover (millionc)
AJL OPHTHALMIC
11
Primary business / Areas of activityAgro-food, Human Food and Nutrition, Environment and Industry.
Company profileBiotalde Laboratories is a private company, located in Galdakao (Bizkaia), working within the FoodIndustry and Environment-fields. It is especially focused on Food Safety, developing programs withthe HACCP/APPCC system and food and drinks microbiological control. In the environmental area,the objective is the analytic support to the diagnostic of the biological quality of air, environmentand water through microbiological determinations. Biotalde´s work is based on a Quality ManagementSystem according to ISO 9001:2000 with the following scope:· Food and drinks microbiologic control.· Water microbiologic, physical and chemical control.· Legionella preventive control (Legionella according to ISO 17025:2005).· Environmental and surfaces microbiologic control.Biotalde, with more than 15 years experience as an independent laboratory and where highly qualifiedtechnical professionals are specialised in Hygiene, Food Technology and Environmental areas, offersmodern laboratory installations, bibliography and informatic supports, and integration into technologicalcentres.
Key wordsFood safety, environment, HACCP/APPCC, microbiological control of food and water, air quality,legionellosis, hygiene, food technology, microbiological essays, biosensors.
5 5-50 50
Address:Zabalea, 1348960 Galdakano · BizkaiaSpainContact person:Nieves ZabalaTelephone:+ 34 944566589Fax:+ 34 946009110E-mail:[email protected]:www.biotalde.comFounding year:1988Employees:10Annual turnover (millionc)
ANÁLISIS BIOLÓGICOS BIOTALDE
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Primary business / Areas of activityR&D, Manufacture, Production, Services. Agro-food, Human Food and Nutrition, Veterinary Science.
Company profile1. Analytical Services- Diagnosis of animal diseases: with this purpose Analítica Veterinaria counts on expertise in the
microbiology, parasitology, biopathology, histology and molecular biology areas. These techniquesare applied to both cattle and small animals.
- Food safety: Analítica Veterinaria offers its services of food microbiological analysis to agro-foodand consultant companies related to this area.
- Clinical approaches following the “Good Clinical Practices”: Analítica Veterinaria is also participatingin clinical approaches working directly for pharmaceutical companies or for other firms involvedin the design of trials for the study and registration of pharmaceutical compounds.
2. Veterinary Consulting- Design and lay out of sanitary development programmes for cattle, especially related to improvement
of milk quality.- Introduction of “Good Clinical Practices” quality system in cattle farms.
3. Training and Dissemination- Design and spread of training activities about animal diseases for vets, agronomic engineers and
farmers. These activities include courses, publications and brochures.4. Research and Development- Analítica Veterinaria is participating in several research projects in order to develop new diagnostic
techniques of interest for cattle raising and for the agro-food industry.
Key wordsAnimal disease diagnostics, ruminant mastitis, biochemistry, microbiology, serology, milk quality,clinic assay, veterinary consulting, food analysis, diagnostic techniques.
5 5-50 50
Address:Aritz bidea, 18b48100 Mungia · BizkaiaSpainContact person:Iñigo Escobal FuldainTelephone:+ 34 946744251Fax:+ 34 946744251E-mail:[email protected]:www.analiticaveterinaria.comFounding year:1991Employees:7Annual turnover (millionc)
ANALÍTICA VETERINARIA
13
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Human Health, InfectiousDiseases, Allergy, Inflammation.
Company profileBial Industrial Farmacéutica, S.A. is a company focused on the manufacturing and commercialisationof allergenic extracts for diagnostic and treatment (vaccines) of allergic diseases. It has a R&DDepartment specialised in immunotherapy with biological products, in which several biotechnologicalresearch lines are carried out (recombinant DNA and monoclonal antibody production). Several Ethicspecialities, also for human use, are commercialised, like antimicrobial agents, antiinflammatoryagents, antiasthmatics, antihistaminics, glucocorticoids, etc.
Key wordsVaccines, allergens, immunoallergology, ethic specialities.
5 5-50 50
Address:Alameda Urquijo 27, 1º48008 Bilbao · BizkaiaSpainContact person:Alberto Martínez GárateTelephone:+ 34 944438000Fax:+ 34 944438016E-mail:[email protected]:www.bial.comFounding year:1941Employees:194Annual turnover (millionc)
BIAL INDUSTRIAL FARMACÉUTICA
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Primary business / Areas of activityR&D, Human Health, Suppliers and Services.
Company profileBIOBIDE is a Biotechnology Company structured around a Technology Platform with two key components:BIOTECHNOLOGY and AUTOMATION, which are brought together to offer to the industry and thescientific community an innovative model for the drug development process.Biotechnology: integrating the Zebra fish animal model (Danio rerio), an in vivo model with a highdegree of genetic homology with humans, 85%.Automation: robotics, optical analysis and bioinformatics technologies adding value to their R+D+I processes.BIOBIDE is located in the Miramón Technological Park in a 1000 square m with modern technologies,in San Sebastian, Spain.BIOBIDE aims to increase its customer´s success by developing and providing preclinical services witha platform High Throughput Screening (HTS) in an automated process, doing a mass testing of compoundseligible for use as drugs. In this way, BIOBIDE generates quickly and with a reasonable cost, highlyinformative results, giving its clients a competitive advantage for the drug discovery and development.BIOBIDE offers mainly two different services:· Toxicity assays: Cardio toxicity, Teratogenesis, General toxicity (Acute toxicity), and Ototoxicity assays.· Efficacy assays: for Cancer (Angiogenesis inhibition assay), SNC-Alzheimer (Acetilcolinesterasa
inhibition assay) and Bone and Cartilage (Bone destruction-generation assay).All of this is carried out in an excellent working environment of Good Laboratory Practice to provideefficacy and toxicity assays under GLP´s to Pharmacutical and Biotech companies over the world.
Key wordsHTS, in vivo Zebra fish automated screening, drug discovery services, outsourcing, efficacy and toxicityassays, QT prolongation, Angiogenesis inhibition assays, automation, validated.
5 5-50 50
Address:Parque Tecnológico de San SebastiánPaseo Mikeletegi, 5820009 San Sebastián · GipuzkoaSpainContact person:Arantza MurianaTelephone:+ 34 943309360Fax:+ 34 943309370E-mail:[email protected]:www.biobide.esFounding year:2005Employees:19Annual turnover (millionc)
BIOBIDE
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Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Environment and Industry,Environmental Applications.
Company profileBIOFINDER is a biotechnological company offering innovative microbiological analysis methods.Our core product is the result of a project developed by Inasmet-Tecnalia, and is based on an innovativesensor for the detection of the most common microbiological parameters both in environmental andfood industry. That is to say, E. coli, Enterococcus, total Coliform and total Aerobic count.This product has been customised with a user-friendly design, allowing a remote and in situ wateranalysis and showing quantitative results in less than 10 hours. Qualitative tests are available in ashorter period of time (3 hours). The offer is completed with specific growth media and a fieldadapter.
Key wordsE.coli, coliform, enterobacteria, microbiology, drinking water, Escherichia coli, agar media, bacteria,colony counting, contamination, culture media, early warning, fecal contamination, food test, GMP,HACCP, HPC, membrane filtration, microbiology, microcolonies, on-line, presence/absence, rapid tests.
5 5-50 50
Address:Parque Tecnológico de San SebastiánPaseo Mikeletegi, 220009 · San Sebastián · GipuzkoaSpainContact person:Igor AristizabalTelephone:+ 34 943000926Fax:+ 34 943000927E-mail:[email protected]:www.biofinder.esFounding year:2006Employees:1Annual turnover (millionc)
BIOFINDER
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Primary business / Areas of activityR&D, Services, Distribution and commercialisation Human Health, Ophthalmology.
Company profileBioftalmik is a biotechnological company specialised in the ophthalmic field.Our main objective is to design and develop diagnostic, prognostic and therapeutic systems for eyediseases and biodevices for ophthalmic surgery. Bioftalmik focus its activities on the generation ofinnovative biotechnological solutions through the combined application of x-omics sciences likeproteomics, genomics and metabolomics with molecular and cellular biology techniques.Bioftalmik is structured around 4 business units:1. Diagnostics.2. Therapeutics.3. Biodevices.4. Services.Bioftalmik has developed an exclusive Tear Biomarker Platform for searching novel markers andtherapeutics target in tear fluid.
Key wordsBiotechnology, ophthalmic research, impression cytology, dry eye, glaucoma, X-omics technologies,diagnostic kits, biodevices/biodispositives.
5 5-50 50
Address:Parque Tecnológico de Bizkaia.Edificio 800 · 2ª Planta48160 Derio · BizkaiaSpainContact person:Jon Careaga GoicoecheaTelephone:+ 34 944069659Fax:+ 34 946562379E-mail:[email protected]:www.bioftalmik.comFounding year:2007Employees:10Annual turnover (millionc)
BIOFTALMIK
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Primary business / Areas of activityR&D, Development and commercialisation. Agricultural and forest sector.
Company profileBiofungitek is a new biotechnological company that develops different kinds of biofungicide productsfor control of fungus disease, to provide good plant protection, as well as a safe application for users,consumers and the environment.Our objectives are to develop and market efficient safe biofungicides.
Key wordsBiofungicide, plant protection, post harvest control.
5 5-50 50
Address:Parque Tecnológico de BizkaiaEdificio 800 · 2ª planta48160 Derio · BizkaiaSpainContact person:Sergio Alava VillateTelephone:+ 34 685510350E-mail:[email protected] year:2008Employees:1Annual turnover (millionc)
BIOFUNGITEK
18
Primary business / Areas of activityR&D, Suppliers and Services-Support, Equipment, Agro-food.
Company profileBIOLAN Microbiosensores is a young biotechnology company that develops, produces and commercialisesbiosensors for the measurement of gluconic and malic acid in musts and wines, as well as otherbiosensors of interest to the food and agricultural industries.
Key wordsBiosensors, food and agricultural industries, wine/musts.
5 5-50 50
Address:Parque Tecnológico de BizkaiaIbaizabal bidea, Edificio 800 · 2ª planta48160 Derio · BizkaiaSpainContact person:Pablo Alonso RodríguezTelephone:+ 34 946574161Fax:+ 34 946574164E-mail:[email protected]:www.biolanmb.comFounding year:2006Employees:3Annual turnover (millionc)
BIOLAN MICROBIOSENSORES
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Primary business / Areas of activityR&D, Manufacture, Production, Services, Human Health.
Company profilePharmaceutical company specialised in manufacturing/production of big-scale injectable solutionsfor third parties.
Key wordsCMO, injectable solutions.
5 5-50 50
Address:Polígono Industrial s/n01118 Bernedo · ÁlavaSpainContact person:Jordi AltarribaTelephone:+ 34 945378238Fax:+ 34 945378228E-mail:[email protected] year:1992Employees:71Annual turnover (millionc)
BIOMENDI
20
Primary business / Areas of activityR&D, Drug Discovery, Diagnostic Products, Manufacture, Services, Human diseases.
Company profileBrainco will take advantage of the opportunity of a unique working model such as the post-mortemhuman brain, and in this system it will apply the most advanced technology currently available inthe field of Genomics and Proteomics, to identify therapeutic targets against which drugs that combatmental diseases can be directed.Therapeutic targets: These targets are of great interest to pharmaceutical and biotech companiesworking in the field of emotional disorders. Once they have been validated in animal models, theycan be used to design and screen new drugs to treat these diseases.Genes and proteins identified as therapeutic targets can be used to construct transgenic animalmodels (mice) in which the expression of these targets is altered. These transgenic mice can beemployed as a model to functionally validate the target that is abnormally expressed, and as a toolto screen and functionally validate new drugs for the treatment of these diseases.Drugs: For other identified targets technological partners will be sourced amongst small pharmaceuticaland biotechnology companies, in order to complete the drug’s next developmental phase. In thiscase the objective is to develop a molecule that shows activity in the animal model produced forthe target in question.Biological markers: There are no biological diagnostic tests for mental diseases. Given that differentiallyexpressed candidates will be validated, markers will be available for their diagnosis and prognosis.These markers can be marketed and analyzed as a group in a DNA-chip or individually.
Key wordsHuman diseases, Psiquiatric diseases, Multiple Sclerosis, Epilepsy, Major Depressive Disorder, BipolarDisorder, Genetic, Proteomic, Brain, Transgenic Animal Models, Therapeutic Targets, DiagnosisTechniques, Drug Discovery, DNA chip, Proteins, Gens.
5 5-50 50
Address:Parque Tecnológico de VizcayaEdificio 80148160 Derio · Bilbao · VizcayaSpainContact person:Marcel Ferrer-Alcón, Ph.D.Telephone:+ 34 944064525Fax:+ 34 944064526E-mail:[email protected]:www.brainco.esFounding year:2008Employees:8Annual turnover (millionc)
BRAINCO
21
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation. Human Health, Regeneration(bone, dental etc.).
Company profileBTI Biotechnology Institute is a company dedicated to manufacturing and research in Implantologyand Biotechnology. It is focused mainly on three fields:1. The BTI Dental implant System.2. The "PRGF system": It deals with the use of the proteins contained in the patient’s own blood,
which is drained at the doctor’s office just before the beginning of the treatment. Treated bloodgives place to a plasma rich in growth factors which, applicated on the surgery location, can speedup epitelialisation of tissues and reduce healing time to less than half time.
3. BTI Scan: Software that helps the implantologist to get an accurate diagnosis.
On-Going Formation Courses in Oral Surgery & Implantology are held in different countries.BTI is also a partner of one of the largest dental publishing groups in Europe (Team Work).
Key wordsDental implant, image planification and simulation, tissue reparation and regeneration, biomaterials,engineering, cellular cultures, experimental surgery in animals, chemical synthesis, PRGF, oral surgery,growth factors, biotechnology, diagnosis, facial rejuveneration.
5 5-50 50
Address:Parque Tecnológico de ÁlavaLeonardo da Vinci, 14b01510 Miñano · ÁlavaSpainContact person:Eduardo AnituaTelephone:+ 34 945140024Fax:+ 34 945154187E-mail:[email protected]:www.bti-implant.es / www.prgf.orgFounding year:1999Employees:215Annual turnover (millionc)
BTI BIOTECHNOLOGY INSTITUTE
22
Primary business / Areas of activityR&D, Production and Services, CMO
Company profileDRO BIOSYSTEMS supports the advance of biotherapy treatments by providing the industry with cGMP-compliant production process development and technology for bioprocesses and therapeutic cellsproduction.We offer our products and services to companies seeking for in-licensing opportunities and companiesapproaching pre-clinical and early clinical trials.Biopharmaceuticals production process development:Design and development of cGMP-compliant production processes for biopharmaceuticals in certifiedfacilities.Static Support Bed technology:Proprietary technology for bioprocesses and therapeutic cells production in contained devices. This technology is available for licensing and enables researchers and companies to develop bioreactorsand produce anchorage dependent cells in a contained environment. Preferred applications for SSBtechnology are therapeutic cells production and industrial processing of biomolecules.
Key wordsBiotherapeutics, bioprocess, SSB technology, biomolecules, fermentation, downstream processing,purification, plasmid, protein, cell culture.
5 5-50 50
Address:Parque Tecnológico de San SebastiánMiramón, 20020009 · San Sebastián · GipuzkoaSpainContact person:Marcos SimónTelephone:+ 34 943308011Fax:+ 34 943000990E-mail:[email protected]:www.dro.esFounding year:2001Employees:10Annual turnover (millionc)
DRO BIOSYSTEMS
23
Primary business / Areas of activityR&D, Distribution and Commercialisation, Suppliers and Services-Support, CRO.
Company profileDynaKin is a recently founded firm (May, 2004), destined to collaborate with the pharmaceuticalindustry in the realisation of integrated and coordinated studies addressing the requirements ofinvestigational and new drug applications to agencies (for new and generic formulations) and similarlyfor research projects that concern development of new therapeutic strategies. DynaKin has a teamof specialists with extensive experience in drug metabolism, drug absorption, bioanalysis (ourbioanalysis department supports in vitro and in vivo preclinical, phase I, II a and bioequivalencestudies), PK-PD modelling, paediatric pharmacology, prediction of first dose in humans (FTIM) andpharmacogenetics.
Key wordsBioanalysis, therapeutic drug monitoring, good laboratory practices, PK/PD analysis.
5 5-50 50
Address:Parque Tecnológico de BizkaiaEdificio 801-B · 1ª planta48160 Derio · BizkaiaSpainContact person:Nerea Leal EguiluzTelephone:+34 944045504Fax:+34 946559465E-mail:[email protected]:www.dynakin.comFounding year:2004Employees:8Annual turnover (millionc)
DYNAKIN
24
Primary business / Areas of activityR&D and Innovation, Manufacturing, Marketing and Distribution of Ethical and OTC (Over-the-counter)products, Exports of API and finished products, and the recently acquired branch of Animal Health.
Company profileFAES FARMA is a Pharmaceutical Company that has been consistenly established within the SpanishStock Market since the past fourties and has its own R&D and Innovation centre almost since thecompany's foundation, 75 years ago.Currently, FAES FARMA consists of three business units located in Leioa, Madrid and Amadora (Portugal),with manufacturing facilities in Leioa and Amadora, accounting for a surface of almost 20,000 m2
taking both manufacturing plants together.The R&D and Innovation Department, located in the Basque Country headquarters, is divided intothree main areas of activities: Chemical Synthesis, Pharmacotoxicology and Biopharmacy &Pharmaceutical Technology.The main R&D areas of interest, in which some lead and head compounds have been developed are:cancer, immune diseases, and central nervous system diseases, including anxiety and Alzheimer disease.Recently (February 2009), a new chemical entity entirely developed by FAES FARMA has beensubmitted to the European Health Authorities in order to obtain the approval for commercialisationas a treatment for allergic rhinitis and urticaria.This will be an important boost in the worldwide consideration of its R&D quality, creativity, andcapabilities.
Key wordsPrescription drugs, over-the-counter medications, skin-care treatments, raw material, central nervoussystems, osteoporosis, cancer, cardiovascular diseases, allergy, inflammation, autoimmune diseases,chemistry, chemical synthesis, biopharmacy. 5 5-50 50
Address:Máximo Aguirre · 1448940 · Leioa · BizkaiaSpainContact person:Ana MuñozTelephone:+ 34 944818300Fax:+ 34 944818309E-mail:[email protected]:www.faes.esFounding year:1933Employees:419Annual turnover (millionc)
FAES FARMA
25
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Human Health, Oncology, Obstetrics, Gynaecology, Andrology.
Company profileGenetadi Biotech is a company that develops new genetic diagnosis kits specialised in the gynaecologyand oncology biomedical sectors. Our company is integrating its projects of research and developmentin Systems Biology applying the most modern techniques developed after the sequencing of thehuman genome. Genetadi Biotech combines two lines of business:1. Development and commercialisation of its own products: new tests of prenatal diagnosis, infertility,
endometriosis and endometrial cancer.2. Human genetic diagnosis services: cytogenetic, molecular genetics, quantitative PCR, gene-
expression analysis and microarrays of comparative genomic hybridisation (aCGH).
Key wordsHuman genetic diagnostics, gynaecology, oncology, infertility, endometriosis, endometrial cancer,prenatal cancer, breast cancer.
Address:Parque Tecnológico de BizkaiaEdificio 800 · 2ª planta48160 DerioSpainContact person:José Luis CastrilloTelephone:+ 34 944044343Fax:+ 34 946566628E-mail:[email protected]:www.genetadi.comFounding year:2004Employees:10Annual turnover (millionc)
GENETADI BIOTECH
26
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation.Human Food and Nutrition, Environmental Applications, Agro-food.
Company profileGUSERBIOT is a technology-based company dedicated to the research, development and productionof wildtype microorganisms for their application in industrial sectors (chemistry, pharmaceutical,agro-food) and in environmental issues (bioremediation, biosensors), as well as to the developmentand production of water pathogen detection kits.
Key wordsIndustrial biotechnology, white biotechnology, fermentation, industrial microbiology, environmentalbiotechnology, bioremediation, food biotechnology.
Address:Polígono Industrial de JúndizJúndiz, 2601015 Vitoria · ÁlavaSpainContact person:Francisca BarberóTelephone:+ 34 945292700Fax:+ 34 945292919E-mail:[email protected]:www.guserbiot.comFounding year:2003Employees:11Annual turnover (millionc)
GUSERBIOT
27
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Human health, Dermatology, Regeneration, Dental.
Company profileHistocell is a biotechnological company that works on tissue engineering and develops new productsfor regenerative medicine.Histocell’s main activity areas are:· Development of innovative products for autologous implant for the regeneration of tissues.· Dermoepidermal deficiencies.· Joint lesions and bone defects.· Three-dimensional structures design.· Drugs and cosmetic testing.· Cell culture research.· Cell amplification services for clinical applications.· Autologous Chondrocytes Implantation.Histocell’s activity is directed to the following sectors:· Pharmaceutics.· Health.· Cosmetics.· Chemical and Engineering.
Key wordsTissue engineering, regenerative medicine, cellular biology.
HISTOCELL
Address:Parque Tecnológico de BizkaiaEdificio 800 · 2ª planta48160 Derio · BizkaiaSpainContact person:Begoña Castro FeoTelephone:+ 34 946567900Fax:+ 34 944036999E-mail:[email protected]:www.histocell.comFounding year:2004Employees:12Annual turnover (millionc)
28
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Agro-food, Environment andIndustry, Human Food and Nutrition, Chemistry, Cosmetics.
Company profileIdoki is a company dedicated to the research, development and production of ingredients and naturalactive principles for food, cosmetic and other uses, using mainly the supercritic fluids technology forextraction, purification, design and production of micro/nano particles, impregnation of materialsand encapsulation.
Key wordsSupercritic fluids, extraction, purification, microparticles, nanoparticles, encapsulation, impregnation,active principles, natural ingredients, cosmetics, foods, pharmaceutical.
IDOKI
Address:Parque Tecnológico de BizkaiaIbaizabal Bidea, Edificio10148170 Zamudio · BizkaiaSpainContact person:Nagore ArdanzaTelephone:+ 34 944005200Fax:+ 34 944048692E-mail:[email protected] year:2006Employees:9Annual turnover (millionc)
29
Primary business / Areas of activityR&D, Manufacture, Production, Services, CRO, CMO.Human Health, Oncology, Allergy, Inflammation, Autoimmune Diseases.
Company profileIkerChem was founded in May 2006 as a spin-off initiative of a leading academic research team ofthe Organic Chemistry Department of the University of the Basque Country (UPV/EHU).Ikerchem is a chemistry-focused drug discovery and development company that is dedicated to thedesign and synthesis of value-added Novel Chemical Entities (NCEs) for pharmaceutical andbiotechnological applications.IkerChem has an in-house platform technology that combines drug design and molecular modelingwith chemical synthesis, capable of generating new product candidates on a sustainable basis andwith a competitive advantage.The principal objective of IkerChem is the development of our own molecule pipeline created in-house and protected by patents, which would consolidate our position in the pharmaceutical industry.The main research lines are focused on therapeutical targets related to cancer epigenetics.
Key wordsDrugs, new chemical entities, materials, design, chemical synthesis, chemistry, cancer, epigenetics,computational design, modelling.
IKERCHEM
5 5-50 50
Address:Pº Mikeletegi, 5620009 San Sebastián · GipuzkoaSpainContact person:Eider San SebastiánTelephone:+ 34 678492181Fax:+ 34 943003460E-mail:[email protected]:www.ikerchem.comFounding year:2006Employees:6Annual turnover (millionc)
30
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Reagents and raw materialsuppliers. Human Health, Agro-food, Environment and Industry.
Company profileThe company was founded in 2000 and its activity is directed to chemistry and micro- andnanotechnology related with diagnostics and biological/biotechnological fields. In this sense, althoughwe are chemists, we develop and manufacture organic and inorganic dispersions that other companiesuse for diagnostics and/or other biological/biotechnological applications. Other applications of ourproducts are directed to the fields of conducting polymers, model colloids, calibration of scientificmachinery.
Key wordsMicro and nanotechnology related to biological sciences; sensors and detectors for diagnostics; organicand inorganic dispersions for clinical diagnostics, veterinary diagnostics; products for separation andpurification of proteins; fluorescent particles; magnetic particles; colloidal dispersions; polymericdispersions; polymer latexes; latex particles; conducting polymers; model colloids.
IKERLAT POLYMERS
Address:Zirkuitu Ibilbidea, 2Local 2820160 Lasarte · GipuzkoaSpainContact person:Joxe Sarobe SorrondeguiTelephone:+ 34 943164724Fax:+ 34 943880727E-mail:[email protected]:www.ikerlatpolymers.esFounding year:2000Employees:3Annual turnover (millionc)
31
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services. Human health.
Company profileIline Microsystems is dedicated to the development and industrialisation of Point-of-Care (POC)devices for medical self-diagnosis and selfcontrol. Iline Microsystems core technology is based onmicrofluidics.The key advantages of such technology are:· Polymer based (extremely low cost at high production volumes).· Passive platforms, as samples as driven by capillary forces only.· Significant reduction of required sample volume.This technology allows a new approach to Test Strip devices.
Key wordsMicrofluidics, Capillary, Point-of-care, POC, Test Strip, Self-diagnosis.
ILINE MICROSYSTEMS
Address:Parque Tecnológico MiramónPaseo Mikeletegi, 54 · 1ª Planta20009 Donostia · GipuzkoaSpainContact person:Iñaki SádabaTelephone:+ 34 943005651Fax:+ 34 943000990Movil:+ 34 688650042E-mail:[email protected] year:2007Employees:3Annual turnover (millionc)
32
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services. Agro-food, Environment and Industry, Consulting, Engineering.
Company profileInkoa Sistemas is an Engineering and Consultancy Company specialised in supplying integral solutionsdirected to the Agro-food sector. Since its beginnings, Inkoa has followed a strategy expansion,diversification and technological innovation that it has brought about the creation of a group company,which are present in the Agro-food and Environmental sectors in the internacional sphere. The solutionscontributed by Inkoa start from the prior studies up to the introduction and start up of the projects,including the elaboration of the preliminary designs and technical projects, technical management,introduction and management of the installations, as well as the training and technical help.
Key wordsAgro-food, electronic, informatics, sensors, biosensors, environment.
INKOA SISTEMAS
Address:Ribera de Axpe,11Edificio D1 · Local 20848950 Asua-Erandio · BizkaiaSpainContact person:Idoia UnzuetaTelephone:+ 34 902998367Fax:+ 34 902998366E-mail:[email protected]:www.inkoa.comFounding year:1992Employees:26Annual turnover (millionc)
33
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services. Human health.
Company profileInnoprot is a biotechnology company focused on the generation of recombinant cell lines intendedfor use in cell-based drug screening. Our efforts are directed to increase speed and efficiency of invitro assays, allowing the collection of more information about the compounds in less time thanother biological systems.The types and formats of our products fit the specific needs of our customers, which lets them choosebetween kits for simple cell-based assays, kits for High Content Analysis and kits with higher quantityof cells for High Throughput Screening. Innoprot offer also includes customised products/services,which allow us to offer a global solution to the compound screening needs.
Key wordsCell based assay, HTS, HCS, Primary cells, High throughput screening, Stable transfected cell lines,Cell line development, Assay development, Protein interactions, Screening services, Fluorescent celllines, DNA cloning and protein expression.
INNOPROT
Address:Zitek Mintegia · Bajo Rectorado · UPV/EHUBarrio Sarriena48940 Leioa · BizkaiaSpainContact person:Clarisa SaladoTelephone:+ 34 944005355Fax:+ 34 946013455E-mail:[email protected]:www.innoprot.comFounding year:2007Employees:8Annual turnover (millionc)
34
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Environment and Industry,Chemistry, Environmental Applications.
Company profileInteman SA was founded in 1980 and has been developing, manufacturing and marketing chemicalproducts for more than 20 years. Over the last 10 years Inteman SA has reorganised its business byimplementing the biotechnology in his RDI process. At this moment, Inteman SA is a companyspecialised in biodetergency cleaning products, with high standards of workplace health & safetyand environmental protection, to be used by the institutional, industrial and commercial cleaningindustry. The biotechnological products, sold under the trademarks: Bioteman and Bio100, areformulated with a proprietary blend of microorganism plus a mixture of enzymes and biodegradablesurfactants. Inteman SA has implemented and maintains a Quality Management System and anEnvironmental Management System. Inteman is certified in ISO 9001:2000, ISO 14000:2004 andEMAS (Eco-Management and Audit Scheme of the EU). The sales network has been expanded allover Spain with more than 50 highly skilled sales persons.
Key wordsBiodetergency, bioremediation, cleaning, bioteman bio100.
INTEMAN
Address:Polígono Industrial de JúndizLermanbide, 2301015 Vitoria · ÁlavaSpainContact person:Miguel Ángel Pérez Ortiz de ElgueaTelephone:+ 34 945292100Fax:+ 34 945290327E-mail:[email protected]:www.inteman.comFounding year:1980Employees:22Annual turnover (millionc)
35
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Agro-Forest-Ornamental,Plant Micropropagation, Nursery Industry.
Company profileINVITROTEK S.L. is a recent spin-off from the Basque Institute for Agrarian Research and Development(NEIKER-Tecnalia). This company was created with the main objective of promoting technology transferin biotechnology between a public research institution and the private sector. INVITROTEK S.L.commercialise products and techniques developed at Neiker-Tecnalia that have a commercial potencial.We offer advanced technology for vegetative multiplication and plant micropropagation (organogenesisand somatic embryogenesis) of adult individuals to the nursery industries. Our two business lines are:· High efficiency protocols for in vitro propagation of vegetable species.· “Customises” production of high quality and improved plant by micropropagation.
Key wordsTechnology transfer, biotechnology, plant sciences, plant micropropagation, organogenesis, somaticembryogenesis, adult individuals, nursery industry, Neiker-Tecnalia.
INVITROTEK
Address:Parque Tecnologico de BizkaiaEdificio 800 · 2ª planta48160 Derio · BizkaiaSpainContact person:Eneko OchoaTelephone:+ 34 680118418Fax:+ 34 944030609E-mail:[email protected] year:2008Employees:1Annual turnover (millionc)
36
5 5-50 50
Primary business / Areas of activityPAT software, LIMS, on demand data analysis, software development, bioinformatics, R&D ,manufacture.
Company profileKB data mining S.L. was created on 2007 to offer bioinformatic products for pharma and biosciencesmarket. The company is based on horizontal software based technologies, oriented to simulation,optimisation and analysis applied to pharma and biosciences vertical markets. Following this, weoffer PAT related simulation and optimisation solutions, genomic and proteomic potential biomarkerdiscovery software, LIMS and on demand data analysis as well as turnkey projects.
Key wordsPAT, biomarker discovery software, LIMS, applied machine learning.
KB DATA MINING
Address:Plaza Aristondo 4, bajo20740 Zestoa · GipuzkoaSpainContact person:Josu GaldianoTelephone:+ 34 943897297Fax:+ 34 943132445E-mail:[email protected]:www.kbdatamining.comFounding year:2007Employees:6Annual turnover (millionc)
37
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services.Agro-food, Environment and Industry, Cosmetics.
Company profileIndependent company dedicated to the research and provision of services around microbiologicaland chemical essays in food, water and cosmetics. Certified by Spanish ENAC according to ISO 17025and homologated for training in the food sector. It has two labs, in Vitoria and Bilbao.
Key wordsMicrobiological and chemical analyses, quality systems, APPCC, ISO - 9000, BRC, training, ENACcertification.
LABORATORIOS BROMATOLÓGICOS ARABA
Address:Pintor Obdulio Lopez de Uralde, 301008 Vitoria · AlavaSpainContact person:Fernando Pérez AguirreTelephone:+ 34 945200015Fax:+ 34 945225934E-mail:[email protected]:www.laboratoriosaraba.comFounding year:1989Employees:22Annual turnover (millionc)
38
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Suppliers and Services, Human Health.
Company profileLaboratorium Sanitatis, S.L. is a recently created pharmaceutical company, conceived to give answerto the requirements of the sanitary and pharmaceutical sector. The main goal of Laboratorium Sanitatisis to provide a pharmaceutical development area, under the most severe control of GMPs, GLPs andCFR 21. The aim of the company is to contribute to new pharmaceutical product launching by promotingtheir development into the industrial manufacturing area. Our laboratory is located in the TechnologyPark of Alava within a 1470 m2 ground area. Laboratorium Sanitatis, S.L. has specific equipment andfacilities to manufacture different dosage forms:· Solid forms (tablets, capsules).· Semi-solids forms (creams, ointments, emulsions, gels).· Liquid forms (syrups, drops, solutions).
Key wordsPharmaceutical development, contract manufacturing, pilot batches, clinical testing batches.
LABORATORIUM SANITATIS
Address:Parque Tecnológico de ÁlavaLeonardo Da Vinci, 1101510 Miñano · ÁlavaSpainContact person:Itziar Echevarría LópezTelephone:+ 34 945298144 Ext. 106Fax:+ 34 945298217E-mail:[email protected]:www.labsan.comFounding year:2004Employees:8Annual turnover (millionc)
39
5 5-50 50
Primary business / Areas of activityR&D, Human Health.
Company profileThe company is focused on development and subsequent comercialisation of surface functionalisedbiomedical devices.
Key wordsFuncionalisation, surface treatments, protheses, implants, tissue regeneration, dental, surgery,traumatology, orthopaedics.
LIFENOVA BIOMEDICAL
Address:Parque Tecnológico San SebastiánMikeletegi Pasealekua, 2 · Edificio Inasmet20009 San Sebastián · GipuzkoaSpainContact person:Iñigo Braceras IzaguirreTelephone:+ 34 943000924Fax:+ 34 943000927E-mail:[email protected]:www.lifenova.comFounding year:2002Employees:2Annual turnover (millionc)
40
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Import/Export, Distribution and Commercialisation. Human Health.
Company profileFrom its beginnings, Laboratorios LITAPHAR has assumed a commitment with the society and theinstitutions related with the health.The basis of LITAPHAR lies on a research group of scientists with experience in chemistry-pharmaceuticalprojects. The human equipment of Litaphar is highly qualified in the generation of active principles,reformulation of medicaments and in the development of industrial chemistry processes.Litaphar develops generic medicines throughout bioequivalence studies, the acquisition of registriesfor the generic medicine commercialisation and the specific medicine development by means ofcollaboration agreements.
Key wordsGenerics, phytotherapy, gynaecology, pharmaceutical, medicinal, cosmetic, sanitary products.
LITAPHAR
Address:Orendaundi, 9Bº Landeta20730 Azpeitia · GipuzkoaSpainContact person:Iñigo Juaristi CortaTelephone:+ 34 943157299Fax:+ 34 943127297E-mail:[email protected]:www.litaphar.comFounding year:2001Employees:7Annual turnover (millionc)
41
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution and Commercialisation. Human Health.
Company profileMDRenal is a privately held biotechnology company focusing on the development of mass-spectrometrybased tools for targeted metabolomics, the analysis of hundreds of metabolites in complex mixturesas blood or urine.Metabolomics holds the promise of significantly reducing attrition rates in the drug discovery processby giving valuable early information for lead selection, on mechanism of action and in drug safetyassessment. At MDRenal we are using our extensive knowledge in biochemistry, organic chemistry,mass-spectrometry and bioinformatics to created ground-breaking solutions for the rapid identification,quantification and interpretation of metabolite biomarkers in blood and urine.MDRenal is currently tuning its technology for metabolite identification and data analysis into acomplete bioanalytics platform to make mass-spectrometry based metabolomics easier and moreaccurate then ever.The bioanalytical challenge of quantification and identification of biological matrix constituents areat the very heart of MDRenals product development. A mixture of short-, mid- and long term researchdriven projects addresses the metabolomics and personalised diagnostics markets with a series oftailored and innovative products.We are currrently developing kits for the market’s fastest mass-spectrometric identification andquantification of hundreds of metabolites with broad metabolite coverage.
Key wordsMetabolomics, mass spectrometry, biochemistry, diagnostics, biomarkers, bioinformatics.
MD RENAL
Address:Parque Tecnológico de San SebastiánPaseo Miramon 18220009 San Sebastián · GipuzkoaSpainContact person:Niels ReichardtTelephone:+ 34 943005309Fax:+ 34 943005314E-mail:[email protected]:www.mdrenal.comFounding year:2008Employees:5Annual turnover (millionc)
5 5-50 50
42
Primary business / Areas of activityR&D, Manufacture, Production, Services, Human Health, Infectious Diseases, Central Nervous System,Oncology.
Company profileMidatech Biogune S.L. is a state of the art facility for the design and manufacture of glyconanoparticlesto cGMP standards. The facility, which opened in March 2007, is situated in Bilbao, Spain, and is partof Midatech Group Ltd, a company dedicated to developing its glyconanoparticles for a wide rangeof therapeutical applications.Midatech Group Ltd is a world leader in the design, synthesis and manufacture of biocompatiblenanoparticles. These nanoparticles can be used to create a wide variety of products with novelcharacteristics, functions and applications that have the potential for multiple diagnostic and therapeuticapplications. The creation of the Midatech Biogune plant is a key part of the business strategy.Created in 2000 Midatech has IP covering design, manufacture and application/use of nanoparticlesin both diagnostic and therapeutic pharmaceutical areas. As well as in-house product developmentit is prepared to licence this IP to 3rd Party pharmaceutical and diagnostic development partnerswhilst retaining manufacturing rights. Midatech has exclusive world-wide rights for technology relatingto the synthesis and applications of self-assembling nanoparticles.
Key wordsNanotechnology, biotechnology, drug delivery, synthetic vaccines, nanoparticles, glyconanoparticles,diagnostics, imaging.
MIDATECH BIOGUNE
Address:Parque Tecnológico de BizkaiaEdificio 800 · 2ª planta48160 Derio · BizkaiaSpainContact person:Justin BarryTelephone:+ 34 944034020Fax:+ 34 944034006E-mail:[email protected]:www.midatechgroup.comFounding year:2005Employees:6Annual turnover (millionc)
5 5-50 50
43
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Human Health, Surgery.
Company profileNEOS SURGERY S.L. is a company founded in 2003 focused in R&D, manufacturing and commercialisationof neurosurgical implants. NEOS join the efforts of two well known Technological Centers, andknowledgeable professionals of the Medical Technology sector. At the present moment NEOS hastwo work centers, placed respectively in Donostia-San Sebastián (Gipuzkoa) and Cerdanyola del Vallès(Barcelona). Currently NEOS is present in the market with one innovative craniotomy bone fixationsystem based on Shape Memory material (BHID: Burr Hole Immobilizing Device). The company isin the last development stage of a second complementary cranial fixation system. The company alsodo have expertise in small parts injection moulding, and is carrying out other projects related to newbiomaterials behaviour and customised implants.
Key wordsNeurosurgery, craniotomy, cranial fixation, medical device, surgery, research development, innovation,shape, memory, spinal, implant, nitinol, biomaterials.
NEOS SURGERY
Address:Paseo Mikeletegi, 220009 San Sebastián · GipuzkoaSpainContact person:Lluís Chico RocaTelephone:+ 34 943000917Fax:+ 34 943000927E-mail:[email protected]:www.neosurgery.comFounding year:2003Employees:6Annual turnover (millionc)
44
5 5-50 50
Primary business / Areas of activityManufacture, Production, Services, Distribution, Commercialisation, R&D. Suppliers and Services-Support, Bioinformatics.
Company profileNoray Bioinformatics S.L. (NorayBio) is a Spanish SME placed in the Bioscience building at theTechnology Park of Bizkaia (Spain). Its mission is to provide IT support to biosciences, biomedicineand biotechnology through the design, development and implementation of software.Products developed by NorayBio are divided in four main brands:· Noraymet: Biopharmacy Brand.· Bioinformatics: Systems Biology Brand.· NorayLims: Data integration Brand.· NorayTools: Biological Data Management Brand.NorayBio does also provide tailored bioinformatics services:· Bioinformatics consultancy.· Biological information management and integration software design and development.· Bionformatics outsourcing projects.· Software for diagnosis kits and biosensors.· Biological data integration bioinformatics platforms.
Key wordsBioinformatics, software, biomedicine, biopharmacy, functional genomics, proteomics, metabolomics,computing platforms.
NORAY BIOINFORMATICS
Address:Parque Tecnológico de BizkaiaEdificio 801 A · 2ª planta48160 Derio · BizkaiaSpainContact person:Marta AciluTelephone:+ 34 944036998Fax:+ 34 944036999E-mail:[email protected]:www.noraybio.comFounding year:2002Employees:35Annual turnover (millionc)
45
5 5-50 50
Primary business / Areas of activityR&D, CRO, Consulting, Pharmaceutical Product Development, Human Health, Veterinary Science.
Company profileOndax Scientific is an independent Contract Research Organisation (CRO) dedicated to the provisionof clinical development services for the pharmaceutical industry (Human and Veterinary).Ondax Scientific is committed to the principles of confidentiality, ethical and scientific quality andoperates in accordance with the principles of the International Co-operation on Harmonisation ofTechnical Requirements for Registration of Medicinal Products.We are specialists in the conduct of clinical trials for registration purposes. Our main services include:· Clinical Trials design and conduct.· Monitoring of clinical trials.· Quality Assurance and Regulatory affairs services.· Data management and Biostatistics.· Epidemiological studies.
Key wordsContract research organisation (CRO), GCP, quality assurance, data management, clinical trials, productregistration, animal health studies, human health studies.
ONDAX SCIENTIFIC
Address:Aptdo. 33620280 Hondarribia · GipuzkoaSpainContact person:Patxi SarasolaTelephone:+ 34 943646087Fax:+ 34 943646158E-mail:[email protected]:www.ondax-scientific.comFounding year:2000Employees:8Annual turnover (millionc)
46
5 5-50 50
Primary business / Areas of activityR&D, Human health care with innovative and pioneering technologies in the field of metabolomics.
Company profileOWL Genomics is a biotech company focused on the identification and validation of biomarkers andtherapeutic targets with the aim of developing early diagnostic systems and treatment. To accomplishthis we use innovative technology in genomics, proteomics, metabolomics and bioinformatics andhave established a complete and highly productive platform which supports the advance of ourdevelopments. OWL Genomics is currently introducing the first in vitro plasma based diagnostic forsteatosis (NAFLD) and NASH. In addition to our ongoing research, initially focused on hepatic diseases,we offer our expertise and technology platform to collaborate with pharmaceutical companies andresearch centres in their R&D when metabolomic analyses are required.
Key wordsMetabolomics, liquid chromatography, mass spectrometry, hepatic diseases, diagnosis, biomarkers,therapeutical targets, genomics, proteomics, obesity, non alcoholic steatohepatitis, NASH, steatosis.
OWL GENOMICS
Address:Parque Tecnológico de BizkaiaEdificio 801-A · 2ª planta48160 Derio · BizkaiaSpainContact person:Azucena CastroTelephone:+ 34 944318540Fax:+ 34 944317140E-mail:[email protected]:www.owlgenomics.comFounding year:2002Employees:11Annual turnover (millionc)
47
Primary business / Areas of activityR&D, Manufacture, Production, Services, Human Health, Oncology.
Company profilePharmakine is a biotechnological company that has been designing, developing and commercialisingproducts and bioassays through comprehensive technologies involved in cancer and metastasisresearch, contributing to the understanding of the regulation of cancer in organ-specificmicroenvironments.As part of these bioassays, we offer preclinical evaluation of potential therapeutic drugs through ourwell-established in vivo animal models in which primary and secondary experimental human/murinetumors are studied. These are of great interest for those researchers focusing on the pathophysiologyof cancer and host cell behavior during tumor progression, angiogenesis and metastasis. Researchinvolving other pathogenic processes such as inflammation may also take advantage of our services.In addition, within our clinical research department we focus our efforts towards the developmentof novel approaches that seek for new biomarkers associated to cancer progression.Finally, we provide assistance through collaborative research and we are also willing to establishpartnerships that enforce business development.
Key wordsCancer animal models, Experimental Metastasis models, Preclinical studies, Skin xenografts, Orthotopictumor models, Tumor in vitro assays, Tumor in vivo models, Therapeutic evaluation, Drug evaluation,Pharmacogenomic studies, Molecular cytogenetics, Gene expression analysis, Laser microdissection,Histology services, Immunohistochemistry services, Diagnostic research, Diagnostic devices, FISHprobes, Comparative genomic hybridisation, Transcriptomic services, Quantitative PCR services,Prognostic biomarkers, Tissue culture, Primary Cell culture, Chondrocytes, Mesenchymal Stem Cells,3D-cell cultures, 3D proliferation kit, 3D angiogenesis kit, Spheroids, Customary tissue arrays,Directed therapy.
5 5-50 50
Address:Parque Tecnológico de BizkaiaEdificio 801 · 1º48160 Derio · BizkaiaSpainContact person:Lorea MendozaTelephone:+ 34 944317037Fax:+ 34 944317039E-mail:[email protected]: www.pharmakine.comFounding year:2002Employees:22Annual turnover (millionc)
PHARMAKINE
48
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Human Health, Oncology,Metabolism, Allergy, Inflammation, Autoimmune Diseases, Haematology, Traumatology, Orthopaedics,Pain.
Company profilePioneering Personalised Medicine.Progenika Biopharma S.A. is a privately owned Spanish company founded in April 2000, with theaim of designing and developing tools for Personalised Medicine. The company develops andmanufactures novel DNAchips for Genotyping that can be used in the diagnosis and prognosis ofhuman diseases.More than 90 scientists work at Progenika, whose state of the art facilities are situated in the BizkaiaTechnologic Park, in the outskirts of Bilbao (Spain). Progenika's fully equipped installations arespecifically designed for the production and analysis of DNAchips. This state of the art equipmentis backed up by a team of Computer experts who develop the algorithms and software that facilitatethe automatic interpretation of DNAchip results.Progenika is the matrix of Progenika Group, constituted currently by Proteomika, Abyntek and BRAINco.
Key wordsPioneering personalised medicine, DNAchips, genotyping, diagnosis, prognosis, human diseases.
PROGENIKA BIOPHARMA
Address:Parque Tecnológico de BizkaiaEdificio 801B · 2ª planta48160 Derio · BizkaiaSpainContact person:Laureano SimónTelephone:+ 34 944064525Fax:+ 34 944064526E-mail:[email protected]:www.progenika.comFounding year:2000Employees:82Annual turnover (millionc)
49
5 5-50 50
Primary business / Areas of activityR&D, Human Health, Central Nervous System, Oncology.
Company profileProteomika was established in January 2002 as a subsidiary of Progenika Biopharma S.A in order todevelop and commercialise tools for personalised medicine using proteomic technology. The aim ofthe company is to provide clinical, hospitals and researchers with no invasive test for diagnostic,prognostic and/or prediction of the treatment response in human diseases, as well as to implementfor clinical or pharmacological use of other products related or derivate of our investigation guidelinesand Know How associated.Proteomika is focused in the biomedical area with two interwoven lines:· Diagnostic Line: This activity is centered in the development of new diagnostic immunoassay that
enables the simultaneous detection of multiples markers in the field of gynecology and oncology.· Drug Line: This activity is centered in the identification and validation of proteins as new therapeutic
target in the neurological diseases field.In addition to providing protein-related services to the biotechnology and pharmaceutical industriesthe company is actively involved with in-house R&D projects and collaborates widely with leadingacademics and clinicians. Research is focused on the identification and functional validation ofdiagnostic and prognostic disease markers as well as the identification of potential therapeutic targets.
Key wordsProteomics, pancreatic & bladder cancer, sclerosis, depression, human diseases, diagnostic, prognostic,biomarkers.
PROTEOMIKA
Address:Parque Tecnológico de BizkaiaEdificio 50448160 Derio · BizkaiaSpainContact person:Juan Pedro López AraguasTelephone:+ 34 944064525Fax:+ 34 944064526E-mail:[email protected]:www.proteomika.comFounding year:2002Employees:32Annual turnover (millionc)
50
5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Agro-food, Veterinary Science.
Company profileVacunek SL is a recent spin-off from the Basque Institute for Agrarian Research and Development(NEIKER-Tecnalia). Our two objectives are the development of an efficacious vaccine againstparatuberculosis in cattle that does not interfere with the diagnosis of tuberculosis and the productionof robust PCR-based diagnostic kits for animal diseases.This company was created with the main objective of promoting technology transfer in biotechnologybetween a public research institution and the private sector. Products and techniques developed atNeiker that have commercial potential will be brought to market by Vacunek. Our first marketedproducts are PCR-based diagnostic kits for animal diseases developed at Neiker. However, Vacunek´smain focus is to develop, register and commercialise a new vaccine against paratuberculosis for usein cattle. Johne´s disease or paratuberculosis is an infectious disease produced by Mycobacteriumavium subsp. paratuberculosis that affects primarily ruminants but can also infect many other animals(foxes, rabbits, mice, etc). It has also been suggested that this bacterium might be a factor for thedevelopment of Crohn´s disease in humans. Available commercial vaccines against paratuberculosiscannot be used in cattle due interferences with the test for tuberculosis.
Key wordsTechnology transfer, biotechnology, diagnostics, polymerase chain reaction, infectious diseases, animalsciences, veterinary sciences, vaccine, paratuberculosis, Neiker-Tecnalia.
VACUNEK
Address:Parque Tecnológico de BizkaiaEdificio 800 · 2ª planta48160 Derio · Bizkaia · SpainContact person:Felix BastidaTelephone:+ 34 946573565Fax:+ 34 946573565Movil:+ 34 615700036E-mail:[email protected]:www.vacunek.comFounding year:2006Employees:4Annual turnover (millionc)
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5 5-50 50
Primary business / Areas of activityR&D, Manufacture, Production, Services, Distribution, Commercialisation, Suppliers and Services-Support,Equipment, Reagents and raw material suppliers. Agro-food, Veterinary Science, Human Food and Nutrition.
Company profileVITA AIDELOS is a key company in bringing Biotechnology to society. VITA AIDELOS aims at achievingan ethical and social commitment with the educational development of biotechnology and with "Scienceliteracy". VITA AIDELOS believes in RD&I since its establishment in 2004. The company is dedicated tothe development of experimentation kits related to DNA analysis and microbial bioproduction.These biotechnology kits have been designed to make it possible to carry out experiments and diagnosesbased on biotechnology in classrooms, museums and science fairs, similar to those carried out inresearch or industrial laboratories. Our products may be used at Secondary Schools, Occupational TrainingCentres, Universities, Museums and Science Parks. VITA AIDELOS manufactures ten different BiotechnologyKits. It has obtained three patents related to these kits, which were jointly developed with the DNABank in the University of the Basque Country. The Biotechnology Kits can be used by Suppliers, EducationalInstitutions, Foundations, Biotechnology companies, Research centres, Museums and science parks,which wish to make their activity known to society. Our aim is to spread scientific advances made inthe field of Biotechnology and to help society understand science by encouraging critical analysis.The company collaborates with the DNA Bank in the University of the Basque Country to develop newproducts. It is currently working in two different R&D lines related with the development of health kitsand food quality diagnosis. VITA AIDELOS operates in the Spanish market. However, the company hasstarted its international expansion (first in Europe and then in Latin America).
Key wordsBiotechnology, laboratory, molecular biology, microbiology, practice kits, biotechnology kits, didacticmethod, educative method, formation, diagnosis, rapid diagnosis kits, practice equipment, DNA,transgenic, bioproduction, enzymes, identification.
VITA AIDELOS
Address:Sangroniz Bidea, 6Mód. 1-G48150 Sondika · BizkaiaSpainContact person:Melania Rosique SolaTelephone:+ 34 944069689Fax:+ 34 944710241E-mail:[email protected]:www.vita-aidelos.comFounding year:2003Employees:6Annual turnover (millionc)
Address: Dolaretxe 548006 Bilbao · Bizkaia · Spain
Contact person: Fernando González
Position: Sales Engineer
Telephone: + 34 918061210
Fax: + 34 918061206
E-mail:[email protected]
Website: europe.appliedbiosystems.com
Applera Hispania
Afora
Address: Enrique Eguren 248012 Bilbao · Bizkaia · Spain
Contact person: Javier Martínez
Position: Delegate
Telephone: + 34 944103590
Fax: + 34 944102135
E-mail: [email protected]
Website: www.afora.es
This part of the guide provides a short overview of some companies identified asSuppliers/Distributors, both local companies and multinational subsidiaries. Theydistribute, and in some cases produce, reagents, equipment, instrumentation, etc.for research, development and production of life science products and applications.
Suppliers/Distributors
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Becton Dickinson
Address: Dendaldegi 3920130 Urnieta · Gipuzkoa · Spain
Contact person: María Paz López Mato
Position: Commercial Manager, North
Telephone: + 34 629164150
Fax: + 34 918488105
E-mail: [email protected]
Website: www.bd.com
Beortek
Address: P.A.E. Asuaran · Edificio Artxanda, 4B48950 Asua · Erandio · Bizkaia · Spain
Contact person: Fermín Mijangos Mijangos
Position: Commercial Director
Telephone: + 34 944710366
Fax: + 34 944711137
E-mail: [email protected]
Website: www.beortek.com
Burdinola Comercial Rafer
Address: Ctra. Lekeitio, Km. 53,548289 Amoroto · Bizkaia · Spain
Contact person: Leire Laka
Position: Marketing
Telephone: + 34 946840766
Fax: + 34 946842005
E-mail: [email protected]
Website: www.burdinola.com
Address: La Paz 2848903 Barakaldo · Bizkaia · Spain
Contact person: José Ignacio Redondo Inyesto
Position: Commercial Delegate
Telephone: + 34 944998580
Fax: + 34 944820479
E-mail: [email protected]
Website: www.rafer.es
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Address: Villa de Plentzia, 28 bajo48930 Getxo · Bizkaia · Spain
Contact person: Nuria García
Position: Commercial Delegate
Telephone: + 34 944633811
Fax: + 34 944639218
E-mail: [email protected]
Website: www.hucoa-erloss.com
Address: Novia Salcedo 2248012 Bilbao · Bizkaia · Spain
Contact person: José Manuel Areizaga Líbano
Position: Managing Director
Telephone: + 34 944273078
Fax: + 34 944274437
E-mail: [email protected]
Website: www.ctenma.com
Hucoa-ErlössComercial Tecnoquímica Enma
Address: Parque Tecnológico de BizkaiaLaida Bidea, Edificio 207 C48170 Zamudio · Bizkaia · Spain
Contact person: Iván González
Position: Commercial Delegate
Telephone: + 34 944317705
Fax: + 34 944318066
E-mail: [email protected]
Website: www.inycom.es
Address: Avda. Madariaga 75, bajo48014 Bilbao · Bizkaia · Spain
Contact person: Fernando Ros Sanz
Position: Area Manager
Telephone: + 34 902203070
Fax: + 34 902203071
E-mail: [email protected]
Website: www.izasa.es
Instrumentación y componentes Izasa
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Labomed-Az
Address: C/B. Tomás de Zumarraga, 4801009 Miñano · Álava · Bizkaia · Spain
Contact person: Iñaki Zallo Echave
Position: Director
Telephone: + 34 945222100
Fax: + 34 945200248
E-mail: [email protected]
Millipore Ibérica
Address: C/ Iturribide 17, 1º48006 Bilbao · Bizkaia · Spain
Contact person: Efrén Isusi Neira
Position: Applications Specialist
Telephone: + 34 609016502
Fax: + 34 944164164
E-mail: [email protected]
Website: www.millipore.com
Proquinorte
Address: Alameda Urquijo, 8748013 Bilbao · Bizkaia · Spain
Contact person: Xabier Gaztelu
Position: Commercial Director
Telephone: + 34 902999211
Fax: + 34 944416873
E-mail: [email protected]
Website: www.proquinorte.com
Address: Plaza de los Estudios 420011 San Sebastián · Gipuzkoa · Spain
Contact person: José Manuel Fernández
Position: Managing Director
Telephone: + 34 943466577
Fax: + 34 943466377
E-mail: [email protected]
Website: www.quimibacter.com
Quimibacter
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Address: Travesía B. de Uribarri 1, 3ºD48007 Bilbao · Bizkaia · Spain
Contact person: Juan Jiménez Rodríguez
Position: Managing Director
Telephone: + 34 954999130
Fax: + 34 954252362
E-mail: [email protected]
Website: www.vitrosp.com
Vitro
Address: Polígono Industrial Aurrera, 3648510 Trapaga · Bizkaia · Spain
Contact person: Santos Hernández
Position: Administration
Telephone: + 34 944721745
Fax: + 34 944721126
E-mail: [email protected]
Website:
Sul
Address: Parque Tecnológico de BizkaiaEdificio 804 · 48160 Derio · Bizkaia · Spain
Contact person: Iñaki Ajuariagogeascoa
Position: Managing Director
Telephone: + 34 944781181
Fax: + 34 944780770
E-mail: iñ[email protected]
Website: www.teknovas.com
Teknovas
[email protected] INDUSTRIA, MERKATARITZA
ETA TURISMO SAILA
DEPARTAMENTO DE INDUSTRIA,COMERCIO Y TURISMO
mar
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