common drugs & their antidotes
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8/19/2019 Common Drugs & Their Antidotes
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An antidote is a substance that can counteract a form of poisoning. The termantidote is a Greek
word meaning “given against”.
This post will help you familiarize with the common antidotes that are used in the hospital setting.
The following are antidotes that should be familiarized by the nurse to respond to this emergency
situation quickly.
Agent/Drug Antidote
Acetaminophen/Tylenol/Paracetamol acetylcysteine (Mucomyst)
Antcholinesterase atrophine sulfate or pralidoxime
Anticholinergics physostigmine
Benzodiazepines flumazenilBeta blockers glucagon
Calcium channel blockers glucagon
Coumadin/Warfarin phytonadione (Vitamin K.)
Cyanide amyl nitrate, sodium nitrate, sodium thiosulfate
Cyclophosphamide mesna
Digoxin digibind
digoxine immune fab
Dopamine phentolamie (Regitine)
Extrapyramidal symptoms (EPS) diphenhydramine (Benadryl)
Ethylene glycol fomepizole
Fluorouracil leucoverin calcium
Heparin protamine sulfate
Insulin reaction glucose (Dextrose 50%)
Iron deferoxamine
Lead dimercapol, edetate calcium, disodium,
Methotrexate leucovorin calcium
Narcotics naloxone (Narcan)
Neuromuscular blockade (paralytics) anticholinesterase agents
Opioid analgesics nalmefene or naloxone
Potassium albuterol inhaler, insulin & glucose, NaHCO3, kayexalate
Tricyclic antidepressants phyostigmine or NaHCO3