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Letter to the Editor Comment on “Under-the-Flap Crosslinking and LASIK in Early Ectasia with Hyperopic Refractive Error” Avi Wallerstein , 1,2 Mathieu Gauvin, 2 and Mark Cohen 2,3 1 Department of Ophthalmology, Faculty of Medicine, McGill University, Montreal, QC, Canada 2 LASIK MD, Montreal, QC, Canada 3 Department of Surgery, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada Correspondence should be addressed to Avi Wallerstein; [email protected] Received 6 February 2019; Accepted 29 May 2019; Published 1 July 2019 Academic Editor: Suphi Taneri Copyright © 2019 Avi Wallerstein et al. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We read with great interest the article by el-Khoury et al. Under-the-Flap Crosslinking and LASIK in Early Ectasia with Hyperopic Refractive Error” [1]. It is encouraging to see clinical work with the goal of stabilizing the progression of early post-LASIK ectasia and improving visual outcomes. In their article, a combination of excimer laser ablation and corneal collagen crosslinking (CXL) was performed under an existing LASIK flap. Sequential excimer laser ablation with CXL has been previously described for the management of cornea ectasia after LASIK [2–4]. e novelty of el-Khoury’s article is applying this combination “under-flap” instead of per- forming a corneal surface treatment with epithelial removal. While el-Khoury and colleagues included key references on CXL combined with excimer laser ablation in their article, we noted an important omission of the source ref- erence that first introduced and described the “under-flap” approach to CXL in patients with early ectasia. e article “Under-flap stromal bed CXL for early post-LASIK ectasia: a novel treatment technique” was published in Clinical Ophthalmology in December 2016 [5]. is article is the first to describe and report on outcomes of performing CXL performed under a previous LASIK flap. e unintentional omission of this reference might lead the readers to wrongfully believe that Dr. el-Khoury and colleagues were the first to describe an under-flap approach to CXL in the management of early post-LASIK ectasia. We would kindly ask Dr. el-Khoury to update his reference list so that the readers can be better informed of the origins of the under-flap method for CXL. We would like to congratulate the authors for their contribution to the field. Conflicts of Interest e authors declare that there are no conflicts of interest and no financial interest in the subject matter or materials presented herein. References [1] S. el-Khoury, Y. Abdelmassih, M. Amro, E. Chelala, and E. Jarade, “Under-the-Flap crosslinking and LASIK in early ectasia with hyperopic refractive error,” Journal of Ophthal- mology, vol. 2018, Article ID 4342984, 10 pages, 2018. [2] A. J. Kanellopoulos and P. S. Binder, “Management of corneal ectasia after LASIK with combined, same-day, topography- guided partial transepithelial PRK and collagen cross-linking: the athens protocol,” Journal of Refractive Surgery, vol. 27, no. 5, pp. 323–331, 2011. [3] G. D. Kymionis, D. M. Portaliou, V. F. Diakonis et al., “Management of post laser in situ keratomileusis ectasia with simultaneous topography guided photorefractive keratectomy and collagen cross-linking,” Open Ophthalmology Journal, vol. 5, pp. 11–13, 2011. [4] G. Tamayo, C. Castell, P. Vargas, E. Polania, and J. Tamayo, “High-resolution wavefront-guided surface ablation with Hindawi Journal of Ophthalmology Volume 2019, Article ID 4986597, 2 pages https://doi.org/10.1155/2019/4986597

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Page 1: Comment on “Under-the-Flap Crosslinking and LASIK in Early ...downloads.hindawi.com/journals/joph/2019/4986597.pdf · Comment on “Under-the-Flap Crosslinking and LASIK in Early

Letter to the EditorComment on “Under-the-Flap Crosslinking and LASIK in EarlyEctasia with Hyperopic Refractive Error”

Avi Wallerstein ,1,2 Mathieu Gauvin,2 and Mark Cohen2,3

1Department of Ophthalmology, Faculty of Medicine, McGill University, Montreal, QC, Canada2LASIK MD, Montreal, QC, Canada3Department of Surgery, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada

Correspondence should be addressed to Avi Wallerstein; [email protected]

Received 6 February 2019; Accepted 29 May 2019; Published 1 July 2019

Academic Editor: Suphi Taneri

Copyright © 2019 Avi Wallerstein et al. )is is an open access article distributed under the Creative Commons AttributionLicense, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work isproperly cited.

We read with great interest the article by el-Khoury et al.“Under-the-Flap Crosslinking and LASIK in Early Ectasiawith Hyperopic Refractive Error” [1]. It is encouraging to seeclinical work with the goal of stabilizing the progression ofearly post-LASIK ectasia and improving visual outcomes. Intheir article, a combination of excimer laser ablation andcorneal collagen crosslinking (CXL) was performed underan existing LASIK flap.

Sequential excimer laser ablation with CXL has beenpreviously described for the management of cornea ectasiaafter LASIK [2–4]. )e novelty of el-Khoury’s article isapplying this combination “under-flap” instead of per-forming a corneal surface treatment with epithelial removal.

While el-Khoury and colleagues included key referenceson CXL combined with excimer laser ablation in theirarticle, we noted an important omission of the source ref-erence that first introduced and described the “under-flap”approach to CXL in patients with early ectasia. )e article“Under-flap stromal bed CXL for early post-LASIK ectasia: anovel treatment technique” was published in ClinicalOphthalmology in December 2016 [5]. )is article is the firstto describe and report on outcomes of performing CXLperformed under a previous LASIK flap.

)e unintentional omission of this reference might leadthe readers to wrongfully believe that Dr. el-Khoury andcolleagues were the first to describe an under-flap approachto CXL in the management of early post-LASIK ectasia. Wewould kindly ask Dr. el-Khoury to update his reference list

so that the readers can be better informed of the origins ofthe under-flap method for CXL.

We would like to congratulate the authors for theircontribution to the field.

Conflicts of Interest

)e authors declare that there are no conflicts of interest andno financial interest in the subject matter or materialspresented herein.

References

[1] S. el-Khoury, Y. Abdelmassih, M. Amro, E. Chelala, andE. Jarade, “Under-the-Flap crosslinking and LASIK in earlyectasia with hyperopic refractive error,” Journal of Ophthal-mology, vol. 2018, Article ID 4342984, 10 pages, 2018.

[2] A. J. Kanellopoulos and P. S. Binder, “Management of cornealectasia after LASIK with combined, same-day, topography-guided partial transepithelial PRK and collagen cross-linking:the athens protocol,” Journal of Refractive Surgery, vol. 27,no. 5, pp. 323–331, 2011.

[3] G. D. Kymionis, D. M. Portaliou, V. F. Diakonis et al.,“Management of post laser in situ keratomileusis ectasia withsimultaneous topography guided photorefractive keratectomyand collagen cross-linking,” Open Ophthalmology Journal,vol. 5, pp. 11–13, 2011.

[4] G. Tamayo, C. Castell, P. Vargas, E. Polania, and J. Tamayo,“High-resolution wavefront-guided surface ablation with

HindawiJournal of OphthalmologyVolume 2019, Article ID 4986597, 2 pageshttps://doi.org/10.1155/2019/4986597

Page 2: Comment on “Under-the-Flap Crosslinking and LASIK in Early ...downloads.hindawi.com/journals/joph/2019/4986597.pdf · Comment on “Under-the-Flap Crosslinking and LASIK in Early

corneal cross-linking in ectatic corneas: a pilot study,” ClinicalOphthalmology, vol. 11, pp. 1777–1783, 2017.

[5] A. Wallerstein, E. Adiguzel, M. Gauvin, N. Mohammad-Shahi,and M. Cohen, “Under-flap stromal bed CXL for early post-LASIK ectasia: a novel treatment technique,” Clinical Oph-thalmology, vol. 11, pp. 1–8, 2017.

2 Journal of Ophthalmology

Page 3: Comment on “Under-the-Flap Crosslinking and LASIK in Early ...downloads.hindawi.com/journals/joph/2019/4986597.pdf · Comment on “Under-the-Flap Crosslinking and LASIK in Early

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