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ANNUAL REPORT2012 – 2013

APPLIED PSYCHOLOGY &HUMAN DEVELOPMENTBIOCHEMISTRYBIOMATERIALS &BIOMEDICAL ENGINEERINGCELL & SYSTEM BIOLOGYCOMPUTER SCIENCEDENTISTRYLABORATORY MEDICINE &PATHOBIOLOGYMEDICAL BIOPHYSICSMEDICAL SCIENCEPHARMACEUTICAL SCIENCESPHARMACOLOGYPHYSIOLOGYPSYCHOLOGYREHABILITATION SCIENCE

COLLABORATIVEGRADUATEEDUCATIONNEUROSCIENCE

UNIVERSITY OF TORONTO

Collaborative Program In Neuroscience

Director Zhong‐Ping Feng, M.D., Ph.D Business Officer Victoria Simpson Administrative Office FitzGerald Building, Rm 83E 150 College Street Toronto, ON M5S 3E2 Phone: (416) 978‐0746 http://www.neuroscience.utoronto.ca/ p.neuroscience@utoronto



Table of Contents

Executive Summary

Message from the Director............................................................................................. 1

About CPIN ...................................................................................................................... 2

CPIN Board of Directors and Committees .................................................................... 3

CPIN Board of Directors

CPIN Academic Program Committee

CPIN Executive Committee

CPIN Graduate Executives

Participating Academic Units ........................................................................................ 5

Faculty Members........................................................................................................... 5

Student Information........................................................................................................ 6

Enrolled Students.......................................................................................................... 6

Graduating Students ..................................................................................................... 7

CPIN Academic Programs.............................................................................................. 8

Admission Requirements .............................................................................................. 8

Program Requirements ................................................................................................. 8

Master's Level

Doctoral Level

Course List .................................................................................................................... 8

Neuroscience Events...................................................................................................... 9

Distinguished Lectureship Series.................................................................................. 9

2013 U of T Oliver Smithies Lecture ........................................................................... 10

Raymond & Beverley Sackler Distinguished Visiting Neuroscientist .......................... 11

CPIN Research Day.................................................................................................... 12

Sponsors

Poster Presentation Judges and Students

Award Winners

Research Day Organizers

Take Your Underdread to Lab Day ............................................................................. 17

CPIN Student Discussion Group - Neurotalks ............................................................ 17

CPIN Cortex Club ....................................................................................................... 17

Toronto Brain Bee....................................................................................................... 18

Top 10 Winners

Toronto Brain Bee Summer Research Placement

Toronto Brain Bee Event Brief

Toronto Brain Bee Sponsors

Toronto Brain Bee Organizers

High School Neuroscience Course ............................................................................. 20

Neuroscience Seminars .............................................................................................. 20

Neuroscience Conferences and Meetings .................................................................. 20

CPIN Workshops ........................................................................................................ 21

Communications........................................................................................................... 22

Website ....................................................................................................................... 22

Email ........................................................................................................................... 22

Newsletters ................................................................................................................. 22

Facebook .................................................................................................................... 22

Student Achievements ................................................................................................. 23

Student Awards........................................................................................................... 23

Student Publications ................................................................................................... 23

Funding (2012 – 2013) .................................................................................................. 23

Appendix 1: CPIN Faculty Member Distribution.............................................................. 25

Appendix 2: Current CPIN Students ............................................................................... 26

Appendix 3: CPIN Graduates 2012-2013 ....................................................................... 29

Appendix 4: Neuroscience Course List........................................................................... 33

Appendix 5: Distinguished Lectureship Survey Statistics ............................................... 35

Appendix 6:Student Awards............................................................................................ 37

Appendix 7: Student Publications ................................................................................... 39

Appendix 8: Financial Report 2012-2013........................................................................ 43

Executive Summary (2012 – 2013)

Date of the Report: July, 2013 About CPIN 14 participating academic units from 5 faculties Lead faculty: Faculty of Medicine; Administration: Department of Physiology CPIN Board of Directors (17 members)

o Signs Memorandum of Agreement and oversees the general direction of the program

CPIN Academic Program Committee (18 members) o Reviews admission and program requirements, program curriculum and

completion, and program activities CPIN Executive Committee (17 members)

o Reviews and leads the program activities CPIN Graduate Executive Committee (9 members) 341 faculty members affiliated with 55 different departments/divisions/institutes (July

2013), including 286 members from 14 participating units; 16 new CPIN members 180 graduate students currently enrolled (July 2013)

o 77 Masters students o 103 Ph.D. students

52 students completed the CPIN program between July 2012 – June 2013 o 28 Masters students graduated this past academic year o 24 Ph.D. students graduated this past academic year

Academic Program Admission requirements Program requirements (Master’s and Doctoral Levels) Courses Distinguished Lectureship Series Eight CPIN Distinguished lectures between November 2012 – May 2013 Sacker Distinguished Lecture 2013 UofT Oliver Smithies Lecture CPIN Research Day June 10, 2013, MSB, attended by over 240 trainees and faculty members 90 CPIN graduate students presented their posters; 34 faculty judges; 15

Presentation Awards; 12 Student’s Choice Awards Dr. Brian K. Kobilka, Professor at Stanford University School of Medicine and the

2012 Nobel Prize Laureate in Chemistry, delivered the 2013 Raymond and Beverly Sackler Distinguished Lecture, in partnership with International Symposium In Structure Neurobiology (over ~400 attendees; also live-streamed webcast)

17 event sponsors Take Your Undergrad to Lab Day Provided mentoring opportunities for graduate students and research observation

experience for undergraduates 29 undergraduate students, 10 graduate students participated

Neurotalks Round-table setting for neuroscience discussions between students and faculty Five sessions hosted in 2012-2013 covering topics including: connectomics,

neuroenhancement, brain modeling, and neuroscience in the media Cortex Club Informal neuroscience discussion leading by visiting researcher and participating by

trainees and faculty members Toronto Brain Bee 2013 April 5, 2013, Medical Sciences Building Seven faculty members and 21 graduate student volunteers involved 56 student participants from 26 local high schools The first place winner, Sophia Ly, represented Toronto attended the 6th Annual

CIHR Canadian National Brain Bee competition The top three winners, Sophia Ly, Mithunan Ravindran and Olivia Ly, were provided

summer research placements in the neuroscience researcher’s laboratories High School Neuroscience Course Introductory Neuroscience Course taught by Graduate Students 10 sessions, provided a teaching opportunity for graduate students, and served as

the preparation course for Toronto Brain Bee 2013 CPIN Workshops CPIN Workshop – Using the Allen Brain Atlas Online Public Resources (March 2013) CPIN Career Workshop – Non-Conventional Careers (June 2013) Neuroscience Seminars Seminars hosted at U of T and affiliated research institutes are posted at

www.neuroscience.utoronto.ca/events/seminar.htm Neuroscience Conferences & Meetings Neuroscience-related conferences and meetings are posted at

www.neuroscience.utoronto.ca/events/seminar.htm Communications and Program Promotion Website: www.neuroscience.utoronto.ca, updated on a regular basis Email: Over 950 subscribers from across the university and affiliated institutions Newsletters: 6 monthly newsletters produced in 2013 Facebook: Over 260 users Provided a sponsorship for Canadian Association of Neuroscience Annual Meeting

Students Achievements Scholarship and Awards Publications Financial Report

CPIN ANNUAL REPORT 2012-2013 1 �

Message from the Director The Collaborative Program in Neuroscience (CPIN) is the largest collaborative graduate program in the University of Toronto. It adds the neuroscience specialization as a notation to participating masters and doctoral students. The CPIN recognizes graduate courses in neuroscience, identifies/organizes distinguished neuroscience lectures, and hosts an annual poster presentation event. The CPIN also provides volunteer opportunities through organizing high school outreach activities to enhance the leadership training of its graduate students. For the 2012 – 2013 year, the CPIN was funded by 14 academic departments from Faculty of Arts and Science, Faculty of Dentistry, Faculty of Medicine, Leslie Dan Faculty of Pharmacy, and Ontario Institute for Studies in Education of the University of Toronto, as per the Memorandum of Agreement. The lead faculty of the program is the Faculty of Medicine. The CPIN program is reviewed by the School of Graduate Studies and the Ontario Council of Graduate Studies, and the CPIN reports to the Vice Dean Graduate Affairs in the Faculty of Medicine, the lead faculty. The administration of the CPIN is managed under the Department of Physiology. This report summarizes the major activities and events in 2012-2013 under new leadership. We have restructured the organizations of the CPIN and initiated new activities. We encouraged and assisted in the establishment of the Graduate Student Executive Committee to increase the visibility and involvement of the CPIN graduate students and postdoctoral fellows. We also sought additional sponsorship to support CPIN activities. We have conducted student surveys on the academic program. We continue to welcome new ideas and new sponsorship. We are determined to make changes in our best capacity to improve the CPIN programs. We aim to foster a strong and proactive collaborative neuroscience training program, recognize and promote excellence, increase the versatility of the trainees for their career development, enhance the national and international recognition of our neuroscience program, and ultimately attract the best graduate students and postdoctoral fellows to our program. With your support and help, we can achieve these goals. I look forward in the coming year to serving and working with you, the CPIN faculty members, graduate students and postdoctoral fellows, to ensure that the CPIN continues to be recognized nationally and internationally as the strong collaborative neuroscience training program it is. Zhong-Ping Feng, M.D., Ph.D. Director, Collaborative Program In Neuroscience

CPIN ANNUAL REPORT 2012-2013 2

About CPIN The Collaborative Program in Neuroscience (CPIN) is a graduate program offering masters and doctoral degree specialization through the School of Graduate Studies at the University of Toronto (Note: this is not a degree in neuroscience but rather a specialization. Students who fulfill all CPIN requirements receive a notation on their transcript and an official document of program completion). CPIN is the largest collaborative neuroscience graduate program in Canada. There are over 300 faculty members and over 200 graduate students and postdoctoral fellows, from fourteen academic departments across five faculties at the University of Toronto participating in the program. The CPIN faculty members and trainees are located at the University of Toronto and its affiliated teaching hospitals/research institutes. Such a large and versatile community provides a strong basis to cultivate a successful training program supporting excellence, collaboration, innovation, and translational and trans-disciplinary research activities. CPIN is funded by fifteen Academic Departments across five Faculties at the University of Toronto. The lead faculty of the program is the Faculty of Medicine. CPIN reports to the Vice Dean Graduate Affairs in the Faculty of Medicine, and is reviewed by the School of Graduate Studies and the Ontario Council of Graduate Studies. The administration of CPIN is managed under the Department of Physiology. The purposes of the Collaborative Program in Neuroscience are to:

1. Foster a proactive collaborative neuroscience graduate/trainee program at the University of Toronto

2. Recognize and promote excellence, and enhance visibility of the graduate

students and postdoctoral fellows in the neuroscience program at the University of Toronto

3. Create an environment increasing the versatility of the graduate students and

postdoctoral fellows for their career development

4. Enhance the national and international recognition of the University of Toronto neuroscience educational program

5. Attract excellent graduate students and postdoctoral fellows to the University of

Toronto


CPIN Board of Directors and Committees

CPIN Board of Directors

The CPIN Board of Directors reviews and signs the Memorandum of Agreement (MoA) and oversees the general direction of the program. The Board of Directors is composed of: • John Coleman (Interim, Cell and Systems Biology) • Morris Moscovitch (Psychology) • Sven Dickinson (Computer Science) • Morris Manolson (Dentistry) • Reinhart Reithmeier (Biochemistry) • Harry Elsholtz (Laboratory Medicine and Pathobiology) • Peter Burns (Medical Biophysics) • Ruth Ross (Pharmacology) • Stephen Matthews (Physiology) • Katherine Berg (Rehabilitation Science) • Paul Santerre (Interim: Institute of Biomaterials and Biomedical Engineering) • Allan Kaplan (Institute of Medical Science) • Heather Boon (Pharmaceutical Sciences) • Ester Geva (Applied Psychology and Human Development) • Avrum Gotlieb (Lead Faculty: Faculty of Medicine) • David R. Hampson (Honorary director, past CPIN director) • Zhong-Ping Feng (Chair, CPIN Director; Physiology)

CPIN Academic Program Committee The CPIN Academic Committee reviews admission and program requirements, program curriculum and completion, and program activities as per the MoA. The Academic Committee is composed of: • Julie Audet (Institute of Biomaterials and Biomedical Engineering) • Peter Carlen (Institute of Medical Science) • Jonathan O. Dostrovsky (Honorary member: Physiology) • Zhong-Ping Feng (Chair) • David R. Hampson (Honorary member: Pharmaceutical Sciences) • Jeffrey Henderson (Pharmaceutical Sciences) • Kang Lee (Applied Psychology and Human Development) • Peter McPherson (Pharmacology and Toxicology) • Angus McQuibban (Biochemistry) • John Peever (Cell and Systems Biology) • Janice Robertson (Laboratory Medicine and Pathobiology) • Barry J. Sessle (Dentistry) • Bojana Stefanovic (Medical Biophysics) • Martin Wojtowicz (Physiology) • John S. Yeomans (Psychology) • Karl Zabjek (Rehabilitation Science) • Richard Zemel (Computer Science) • CPIN Graduate Executives representative


CPIN Executive Committee The CPIN Executive Committee reviews and leads the program activities as per the MoA, including distinguished lecture selection, Research Day, high school outreach program, sponsorships and faculty-student interactive events. The Executive Committee is composed of: • Oliver Ernst (Biochemistry) • Zhong-Ping Feng (Chair) • David R. Hampson (Honorary member: Pharmaceutical Sciences) • Lili-Naz Hazrati (Laboratory Medicine and Pathobiology) • Jeffrey Henderson (Pharmaceutical Sciences) • Kang Lee (Human Development and Applied Psychology) • John Peever (Cell and Systems Biology) • Ruth Ross (Pharmacology & Toxicology) • Barry J. Sessle (Dentistry) • Molly Shoichet (Institute of Biomaterials and Biomedical Engineering) • Bojana Stefanovic (Medical Biophysics) • Lu-Yang Wang (Physiology) • Albert Wong (Institute of Medical Science) • John S. Yeomans (Psychology) • Karl Zabjek (Rehabilitation Science) • Richard Zemel (Computer Science) • CPIN Graduate Executives representative

CPIN Graduate Executives The CPIN Graduate Student Executive Committee is composed of: Andrew Barszczyk (Outreach Program; Feng Lab) Ceilidh Cunningha (Member in large; Trimble & Wang Lab) Katie Ferguson (Communications; Newsletters, Facebook; Skinner Lab) Vivek Mahadevan (Cortex Club; Woodin Lab) Denis Osipov (Communications: Photographer; Salter Lab) Vladislav Sekulic (Communications: Newsletters; Skinner Lab) Bhanu Sharma (Member in large; Green Lab) Luka Srejic (Discussion Group: Neurotalks; Hutchison Lab) Sonia Sugumar (Special Events: Take Your Undergrad to Lab Day; Carlen Lab) Zhong-Ping Feng (Advisor)


Participating Academic Units Faculty of Arts and Science

Cell & System Biology Computer Science Psychology

Faculty of Dentistry Graduate Department of Dentistry

Faculty of Medicine Biochemistry Biomaterials & Biomedical Engineering (Institute of) Laboratory Medicine & Pathobiology Medical Biophysics Medical Science (Institute of) Pharmacology & Toxicology Physiology Rehabilitation Science

Faculty of Pharmacy

Graduate Department of Pharmaceutical Sciences

Ontario Institute for Studies in Education Applied Psychology & Human Development

Faculty Members University of Toronto faculty members with an interest in neuroscience may join CPIN to receive notifications of upcoming neuroscience events and seminars and be listed as member on our faculty page. Faculty members with an SGS appointment may have their students join CPIN.

During 2012-2013, 16 faculty members joined CPIN. There are currently 341 members of the CPIN faculty and 286 have graduate appointments in 14 CPIN participating graduate units. The distribution of the faculty members is shown in Appendix 1, according to their department of primary appointment. Some members have cross appointments with one or more other graduate departments. (http://www.neuroscience.utoronto.ca/faculty/list.htm)


Student Information

Enrolled Students There are currently 180 graduate students enrolled in CPIN. Appendix 2 includes a list of current CPIN students, including their department affiliation. Number of Current Students from Each Participating Department or Faculty Department or Faculty Masters Ph.D. Total Applied Psychology & Human Development (APD) 0 2 2 Biochemistry (BCM) 0 0 0 Cell & Systems Biology (CSB) 8 7 15 Computer Science (CSC) 0 0 0 Dentistry (DEN) 2 0 2 Institute of Biomaterials and Biomedical Engineering (BME) 2 2 4 Institute of Medical Science (IMS) 32 27 59 Laboratory Medicine and Pathobiology (LMP) 2 4 6 Medical Biophysics (MBP) 2 1 3 Molecular Genetics & Microbiology (MMG) 0 1 1 Pharmaceutical Sciences (PHM) 1 4 5 Pharmacology & Toxicology (PCL) 3 4 7 Physiology (PSL) 15 19 34 Psychology (PSY) 8 26 34 Rehabilitation Science (REH) 1 5 6 Speech-Language Pathology (SLP) 1 1 2 Total 77 103 180 The figure below shows the distribution of current students across participating units.

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Graduating Students A total of 52 students have graduated with the CPIN specialization in the 2012-2013 academic year. Appendix 3 includes a list of CPIN graduating students, including their department affiliation, supervisor, and thesis topic. Number of Graduating Students from Each Participating Department or Faculty Department or Faculty Masters Ph.D. Total Applied Psychology & Human Development 0 3 3 Biochemistry 0 0 0 Cell & Systems Biology 2 0 2 Computer Science 0 0 0 Dentistry 0 0 0 Institute of Biomaterials and Biomedical Engineering

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Institute of Medical Science 13 9 22 Laboratory Medicine and Pathobiology 0 1 1 Medical Biophysics 1 1 2 Molecular Genetics & Microbiology 0 0 0 Music and Health 0 0 0 Pharmaceutical Sciences 1 0 1 Pharmacology & Toxicology 2 2 4 Physiology 3 4 7 Psychology 5 4 9 Rehabilitation Science 0 0 0 Speech-Language Pathology 0 0 0 Total 28 24 52 The figure below shows the distribution of graduating students in the participating units.

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CPIN Academic Programs

The Academic Program Committee has discussed and revised the program requirements. The Admission requirements remain unchanged from the previous year. The CPIN also added a temporary student membership for visiting graduate students to the University of Toronto.

Admission Requirements Applicants who wish to enrol in the collaborative program (at either Master’s or

Doctoral level) must apply to and be admitted to both the collaborative program and a graduate degree program in one of the collaborating units.

Program Requirements

Master's Level The thesis topic must be in the neuroscience area.

The student's supervisor must be a faculty member of CPIN.

The student must complete at least 0.5 full-course (or two 0.25 half-course) equivalent (FCE) for the master's degree chosen from the list of courses approved by the Collaborative Program in Neuroscience.

The student must attend the Annual Research Day & present his/her work at least once.

The student must attend at least 75% (or a minimum of 7) of the CPIN Distinguished Lectureship Series for a minimum of one year in consecutive sessions during their studies.

Doctoral Level The thesis topic must be in the neuroscience area.

The student's supervisor must be a faculty member of CPIN.

All Ph.D. students must complete at least 1.0 FCE course, such as JNR 1444Y Fundamentals of Neuroscience: Cellular and Molecular, or JNS 1000Y Fundamentals of Neuroscience: Systems and Behaviour, or one of several additional courses in cognitive psychology or imaging, or neuroscience related course to be determined by the CPIN Program Committee and posted on the CPIN website.

The student must attend the Annual PIN Research Day and present his/her work at least twice.

The student must attend at least 75% (or a minimum of 7) of the CPIN Distinguished Lectureship Series for a minimum of three consecutive years during their studies.

After completing the M.Sc. or M.A., students who wish to continue on to a Ph.D. degree in Neuroscience must register again and fulfil all the program requirements.

Course List Neuroscience courses offered by the participating units are listed in Appendix 4.


Neuroscience Events

Distinguished Lectureship Series CPIN organized eight lectures in the Distinguished Lectureship Series for the 2012-2013 year. Many of these were co-sponsored with member departments and institutes. All students in the program are required to attend at least 75% (or 7, including the Sackler Lecture) of these lectures. A survey evaluation of the lectures has been conducted. The results are presented in Appendix 5.

Speaker | Dr. Bryan Roth, University of North Carolina Date | November 2, 2012 Time | 2 - 3 PM Title| Pharmacology control of brain function Location | Room 610, Health Sciences Building Host | Dr. John Peever, Associate Professor, Cell and System Biology

Speaker | Dr. Zhigang He, Harvard Medical School and Boston Children's Hospital Date | November 16, 2012 Time | 4 - 5 PM Title| Mechanisms of axon regeneration in adult CNS Location | Room 610, Health Sciences Building Host | Andrew Barszczyk, CPIN Ph.D. Student & Dr. Zhong-Ping Feng, Associate

Professor, Physiology Speaker | Professor Leonard K Kaczmarek, Yale University School of Medicine Date | January 24, 2013 Time | 4:00 p.m. Title | RNA-binding ion channels and the control of sensory sensitivity Location | Room 2172, Medical Sciences Building Host | Dr. Lu-Yang Wang, Professor, Department of Physiology Co-sponsor | Department of Physiology Speaker | Professor Rodolfo Llinas, Thomas and Suzanne Murphy Professor of Neuroscience, New York University School of Medicine Date | April 3, 2013 Time | 2:30 - 3:30 pm Title | Evidence for Thalmocortical Dysrhythmia and its Association with Health

Conditions Location | Worthman Hall, Baycrest Centre Host | Dr. Lee Bartel, Professor, Associate Dean-Research, Faculty of Music, Acting

Director of MaHRC Co-sponsor | Music and Health Research Collaboratory (MaHRC) Funding | Connaught Fund Speaker | Professor Lisa M. Monteggia, University of Texas Southwestern

Medical Centre Date | April 5, 2013 Time | 10:30 - 11:30 am Title | Mechanism of Rapid Antidepressant Action Location | Room 1160, Bahen Centre Host | Dr. Fang Liu, Professor, Departments of Psychiatry and Physiology Co-sponsor | Centre for Addition and Mental Health (CAMH)


Speaker | Professor Timothy Ryan, Weill Cornell Medical College, Cornell University Date | May 2, 2013 Time | 1:30-2:30 pm Title | What your brain uses to think: the biology of synapses and their control Location | MSB 3154 Host | Dr. Lu-Yang Wang, Professor, Department of Physiology Co-Sponsor | Department of Physiology

Funding| BRAIN Platform, Department of Physiology

Speaker | Professor Lara Boyd, University of British Columbia Date | May 3, 2013 Time | 1:00-2:00 pm Title | Sensorimotor physiology and function after stroke Location | Room 1105, Sanford Fleming Bldg Host | Dr. Karl Zabjek, Department of Physical Therapy, Graduate Department of Rehabilitation Science Co-sponsor | Graduate Department of Rehabilitation Science

Speaker | Professor Ivan Soltesz, Chancellor's Professor and Chair of

Departments of Anatomy and Neurobiology, University of California (Irvine) Date | May 10, 2013 Time | 1:00 - 2:00 pm Title | Organization and Control of Hippocampal Chronocircuits Location | Auditorium (WWW2-401), Toronto Western Hospital Host | Dr. Frances Skinner, Associate Professor, Departments of Medicine

(Neurology) and Physiology Co-sponsor | Toronto Western Research Institute (TWRI), UHN, and Center for

Mathematical Medicine (CMM - Fields)

2013 U of T Oliver Smithies Lecture Speaker | Dr. Marc Tessier-Lavigne, President of The Rockefeller UniversityTime | 12:00 – 1:00, April 23 Location | MacLeod Auditorium, MSB2158. Topic | Brain Development and Plasticity: Molecular Control of Neuronal Guidance and Degeneration Sponsors | Faculty of Medicine and Friends of CIHR.

The 2013 U of T Oliver Smithies Lecture was delivered by neuroscientist Marc Tessier-Lavigne, President of Rockefeller University, and recipient of the University of Toronto 2013 Oliver Smithies Lectureship and the 2012 Henry G. Friesen International Prize in Health Research. The 2013 Oliver Smithies Lecture was organized by the Faculty of Medicine and Friends of CIHR. The lecture was also identified as a CPIN Distinguished Lecture. The Faculty of Medicine organized a two hour Neuroscience Panel Meeting and Discussion with Dr. Marc Tessier-Lavigne following the lecture on April 23, with the assistance of Dr. Mike Salter and Dr. Zhong-Ping Feng. On behalf of Dr. George Fantus, Associate Dean Research, Dr. Feng chaired the session. Seven CPIN Faculty Members presented their recent findings, and 22 faculty members and 10 graduate students and postdoctoral fellows attended the interactive meeting and joined the discussion with Dr. Tessier-Lavigne. Dr. Tessier-Lavigne also discussed his view of the near future directions in neuroscience research. He highly praised the research level of the U of T neuroscience researchers and the tight neuroscience community at the U of T. The session ended with Dr. Tessier-Lavigne’s inspirational talk to the trainees, where he emphasized the importance of outstanding young neuroscience researchers staying in academics as well as industry.


Raymond & Beverley Sackler Distinguished Visiting Neuroscientist Speaker | Dr. Brian K. Kobilka, Stanford University Date | June 10, 2013 Time | 4:45 pm Title| Structural Insights into the dynamic process of G-protein coupled receptor activation Location | MacLeod Autitorium, MSB Host | Oliver Ernst, Professor, Department of Biochemistry

Dr. Brian K. Kobilka, Professor at Stanford University School of Medicine and the 2012 Nobel Prize Laureate in Chemistry, delivered our 2013 CPIN Raymond and Beverly Sackler Distinguished Lecture, which is also the keynote lecture of the CPIN Research Day and International Symposium of Structural Neurobiology, chaired by Professor Oliver Ernst. Dr. Kobilka delivered the world-class lecture on structural insights into the dynamic process of G-protein coupled receptor activation, and highlighted the unequivocal contribution of the state-dependent structural characterization of the receptors to drug discovery. The lecture was educational, informative and inspirational. Dr. Brian Kobilka’s lecture was also webcasted and attended off-site by the neuroscientists and trainees from University of Toronto, Queen’s University and McMaster University.

(Photo credits (Photo Credits to Dr. Hong-Shuo Sun)

Raymond & Beverley Sackler Distinguished Visiting Neuroscientists http://www.neuroscience.utoronto.ca/events/sackler.htm2013 CPIN Research Day Program Booklet: http://www.neuroscience.utoronto.ca/events/CPIN_Research_Day.htmInternational Symposium of Structural Neurobiology http://cettesemaine.utoronto.ca/?q=StructuralNeurobiologySymposium


CPIN Research Day The 2013 University of Toronto CPIN Research Day was held on June 10, 2013, in partnership with the International Symposium on Structural Neurobiology, which took place on June 11, 2013. Dr. Brian K. Kobilka, Professor at Stanford University School of Medicine and the 2012 Nobel Prize Laureate in Chemistry, delivered the 2013 Raymond and Beverly Sackler Distinguished Lecture (Page 9). Over 240 graduate students, postdoctoral fellows, faculty members and friends attended the CPIN Research Day.

(Photo credits to Dr. Hong-Shuo Sun)

90 poster presentations were given by the CPIN trainees in the Stone Lobby from 12:30 pm to 4:00 pm. 5 Overall Outstanding Poster Presentations and 10 Outstanding Poster Presentations were recognized by the faculty judges after two rounds of evaluations. The CPIN students also voted for their favourite posters, resulting in 12 Student Choice Poster Presentation Awards. This inter-faculty and inter-department interactive event was a tremendous success. The CPIN Executive Committee would like thank all participants, the poster judges, and graduate student volunteers.

Sponsors The 2013 CPIN Research Day Organizing Committee wish to acknowledge the following 17 sponsors, in addition to the contribution from the 14 CPIN participating departments The Faculty of Medicine Rotman Research Institute Mount Sinai Hospital Samuel Lunenfeld

Research Institute SickKids Research Institute

Neuroscience & Mental Health St. Michael’s Hospital Toronto Western Research Institute Raymond and Beverly Sackler Foundation Ontario Brain Institute

Parkinson Society Canada Olympus Canada Departments of

Anesthesia Computer Science Laboratory Medicine & Pathobiology Pharmacology & Toxicology Physiology Psychiatry Human Biology Program

Poster Presentation Judges

The faculty members evaluated the poster presentations: Ana Andreazza Limor Avivi-Arbe Paul Boutros Sid Croul Suzanne Erb Jim Eubanks Paul Fletcher Susan George Karen Gordon David Hampson

Jeff Handerson Zheng-Ping Jia Bill Ju Rasmus Kiehl Evelyn Lambe Robert Levitan Philippe Monnier Howard Mount Daniel Mueller

Joanne Nash Jose Nobrega Janice Robertson Gerold Schmitt-Ulms Barry Sessle Frances Skinner Shuzo Sugita Hong-Shuo Sun

Franco Taverna Douglas Tweed John Vincent Lu-Yang Wang John Yeomans Karl Zabjek Martin Zack Richard Zemel


CPIN Students and Faculty Members at the CPIN Research Day

(Photo credits to Dr. Albert Wong)

Award Winners Following the Sackler Lecture, Dr. Lili-Naz Hazrati announced the winners of the Student’s Choice Poster Awards, and Dr. Albert Wong announced the Outstanding Poster Presentation Awards and the Overall Outstanding Poster Presentation Awards. Dr. Brian Kobilka joined Dr. Zhong-Ping Feng to present the awards to the winners.

Overall Outstanding Poster Winners Pieter Beerepoot (Ph.D./PCL; Supervisor: Ali Salahpour) Hillary Bond (M.Sc./CSB; Supervisor: Leslie Buck) Helen Chiang (Ph.D./LMP; Supervisor: Janice Robertson) Nancy Dong (PSL; Supervisor: Zhong-Ping Feng) Celeste Leung (M.Sc./PSL; Supervisor: Zhengping Jia)


Outstanding Poster Winners Monique Budani (M.Sc./LMP; Supervisor: Clifford Lingwood) Michael Chang (M.Sc./IMS; Supervisor: Taufik Valiante) Vanessa Ghosh (Ph.D./PSY; Supervisor: Asaf Gilboa) Marielle Deurloo (Ph.D.*/PSL; Supervisor: Zhong-Ping Feng) Doris Lam (Ph.D./PSL; Supervisor: Lyanne Schlichter) Zhong Xu Liu (Ph.D./APH.D; Supervisor: Morris Moscovitch) Adam Mosa (M.Sc./PSL; Supervisor: Martin Wojtowicz) Gabriela Rozanski (Ph.D./PSL; Supervisor: Elise Stanley) Sonia Sugumar (M.Sc./PSL; Supervisor: Peter Carlen) Paul Whissell (Ph.D./IMS; Supervisor: Bev Orser) *international student

Student’s Choice Poster Winners Most Popular: 1 - Soaleha Shams (Ph.D./CSB; Supervisor: Robert Gerlai) 2 - Gang Wang (M.Sc./IMS; Supervisor: Karen Davis) 3 - Aaron Kucyi (Ph.D./IMS; Supervisor: Karen Davis) Outstanding Research: 1 - Soaleha Shams (Ph.D./CSB; Supervisor: Robert Gerlai) 2 - Aaron Kucyi (Ph.D./IMS; Supervisor: Karen Davis) 3 - Gang Wang (M.Sc./IMS; Supervisor: Karen Davis) Visually Effective: 1 - Gang Wang (M.Sc./IMS; Supervisor: Karen Davis) 2 - Daniel Lee (Ph.D./PSY; Supervisor: Adam Anderson) 3 - Soaleha Shams (Ph.D./CSB; Supervisor: Robert Gerlai) Oral Presentation: 1 - Soaleha Shams (Ph.D./CSB; Supervisor: Robert Gerlai) 2 - Gang Wang (M.Sc./IMS; Supervisor: Karen Davis) 3 - David Dukoff (M.Sc./CSB; Supervisor: Les Buck)

CPIN Poster Presentation Awards Details:http://www.neuroscience.utoronto.ca/events/CPIN_Research_Day.htmhttp://www.neuroscience.utoronto.ca/communications/2013newsletter.htm

Overall Outstanding and Outstanding Poster Awardees with Dr. Brian Kobilka and the Poster Judge Organizing Committee.

Student’s Choice Poster Presentation Awardees with Dr. Brian Kobilka and the Award Organizing Committee.

Dr. Brian Kobilka and the CPIN Research Day Organizing Committee. (Photo credits to Dr. Hong-Shuo Sun)


Research Day Organizers The immense success of the 2013 CPIN Research Day is attributable to an enormous team effort from the CPIN faculty members, postdoctoral fellows and graduate students, and CPIN Research Day Organizers, particularly the CPIN Research Day Organizing Committee and CPIN Graduate Executive Committee. Research Day Organizing Committee Zhong-Ping Feng (Chair) Oliver Ernst (also ISNB organizer) Lili-Naz Hazrati Janice Robertson Albert Wong CPIN Graduate Student Executives Andrew Barszczyk Ceilidh Cunningha Katie Ferguson (Liaison) Vivek Mahadevan Denis Osipov Vladislav Sekulic Bhanu Sharma Luka Srejic Sonia Sugumar Sackler Lecturer Invitation Oliver Ernst Workshop Zhong-Ping Feng Janice Robertson Poster Judge Organizing Committee Janice Robertson (Co-Chair) Albert Wong (Co-Chair) Lili-Naz Hazrati Zhong-Ping Feng Student’s Choice Poster Awards Committee Zhong-Ping Feng (Co-Chair) Lili-Naz Hazrati (Co-Chair) Andrew Barszczyk Luka Srejic

Sponsorships Zhong-Ping Feng (Chair) Oliver Ernst Lili-Naz Hazrati Bev Orser Janice Robertson Albert Wong Richard Zemel Event Program Design Katie Ferguson Vladislav Sekulic Poster Site Coordinator Luka Srejic Sonia Sugumar Registration Desk Luka Srejic (Co-Chair) Bhanu Sharma (Co-Chair) Andrew Barszczyk Ceilidh Cunningha Katie Ferguson Vivek Mahadevan Vladislav Sekulic Sonia Sugumar (AV) Photographers Denis Osipov Hong-Shuo Sun Albert Wong Administration Victoria Simpson Rob Reedijk

CPIN Research Day (http://www.neuroscience.utoronto.ca/events/CPIN_Research_Day.htm)


Take Your Undergrad to Lab Day In order to provide opportunities for motivated undergraduates to experience a research setting in graduate school, the CPIN Graduate Executives initiated and created the “Take Your Undergrad to Lab Day” event in April 2013, in collaboration with the Neuroscience Association for Undergraduate Students (NAUS). Coordinated by Sonia Sugumar, CPIN graduate students volunteers mentored the event, in which undergraduates observed the graduate students’ hands-on experiments for a portion of the day, upon being granted the permission of their thesis supervisors. CPIN’s enthusiastic graduate students well accommodated the overwhelming demand from the undergraduates for the event. Undergrad students rated their overall experience as a 9/10 and indicated that they would recommend this event to their peers. The NAUS executive representatives, Amirah Momen and Kweephol Petchsri, collaborated with CPIN in recruiting undergraduate students and helped in organizing this event. The participants in the 2013 Take Your Undergrad to Lab Day

Graduate Student

Supervisor Department Undergrad Students

Ceilidh Cunningham

Dr. William Trimble Dr. Lu-Yang Wang

Physiology Catalina Santos Carrie (Chang Hua) Chen Mohamed Roble

Derek Howard Dr. Lu-Yang Wang Physiology Arya Abdool, Mariam Ebady, Ryan Stagno, Christine Tsilas

Celeste Leung Dr. Zhengping Jia Physiology Nidhi Ravishankar Caiwei Li, Bill Chi

Bhanu Sharma Dr. Robin Green Rehabilitation Science

Annie Zhan

Sonia Sugumar Dr. Peter Carlen Physiology Taylor Brin, Arsalan Mir Seuyoon Hong, Katrina Chiu

Katie Ferguson Dr. Francis Skinner

Physiology Vina Law, Vivian Feng, Xixi Wu

Carlos Florez Dr. Peter Carlen Physiology Jun Ku (Allen) Chung Rohit Mohan, Jelum Raval

Joshua Dian Dr. Peter Carlen Dr. Berj Bardakjian

Physiology/ECE Justin Feng , Fatima-Zahra Maamir, Audrey Zhang

Michal Krawczyk Dr. Peter Carlen Physiology Romeo Penheiro, Natalie Yiu

Margaret Maheandiran

Dr. Peter Carlen Physiology William Cho, Kate Chung Danielle Smalling

(

Photo credits to Sonia Sugumar)


CPIN Student Discussion Group CPIN Graduate Executives have created and introduced a new format of learning into an academic environment steeped in the tradition of large lecture halls. Coordinated by Luka Srejic, Neurotalks offered an informal round-table setting for active neuroscience discussions. Both students and faculty members from a variety of disciplines were invited to participate. Five Neurotalk sessions were hosted in 2012-2013. The topics covered in the Neurotalks include: connectomics, neuroenhancement, brain modeling, and neuroscience in the media. Among the participants were students and post-docs in psychology, physiology, medical science, engineering, and cognitive science, in addition to faculty members from rehabilitation science, psychiatry, and aerospace engineering. http://www.neuroscience.utoronto.ca/events/Neurotalk.htm

CPIN Cortex Club In May 2013, CPIN announced a merger of the University of Toronto Cortex Club to CPIN. Cortex Club is a unique seminar series dealing with cutting-edge topics and significant, challenging issues in neuroscience. It is organized and run by graduate students, and provides an informal and egalitarian environment designed to encourage cross talk and innovation. At each Cortex Club event, a visiting researcher is asked to present a mixture of novel, technical, speculative, and possibly even controversial work or ideas. Attendees are encouraged to ask questions, make comments, and discuss with each other during the invited speaker's presentation. The direction of the discussion is allowed to evolve organically, whether that be down towards the nitty-gritty technical details of a new methodology, or up towards lofty ideas about the nature of the brain and the future of neuroscience. The Cortex Club was originally founded at the University of Oxford in 2009. With the support of the CIHR Sleep and Biological Rhythms Program, the Toronto chapter of the Cortex Club was started in 2012 by Dr. Blake Richards (President of the Club in Oxford from 2010-2011) and Dr. Jimmy Fraigne. Several Cortex Club events in Toronto have been attended to capacity, on subjects including optogenetics, pharmacogenetics, early visual development, and large-scale computer models of the brain. Katie Ferguson hosted the CPIN-Cortex Club on May 10, 2013, in which the CPIN distinguished Lecture speaker, Dr. Ivan Soltesz, Chancellor's Professor and Chair of Departments of Anatomy and Neurobiology, University of California (Irvine) led the discussion. The Cortex Club provides graduate students a chance to interact with the world's leading neuroscientists in a manner that standard seminars or luncheons do not. It also provides invaluable leadership and networking experience for graduate students, helping them to build connections within the global neuroscience community. These principles fit the mandates of CPIN. In the 2013-2014 year, as a part of CPIN, Cortex Club will continue organizing events with leaders in neuroscience as part of our CPIN graduate activities. More information about the University of Toronto Cortex Club can be found at the website cortexclub.ca. http://www.neuroscience.utoronto.ca/events/cortexclub.htm


Toronto Brain Bee The 15th Annual Toronto Brain Bee competition took place in the Medical Sciences Building at the University of Toronto, on April 5, 2013. The competition was an opportunity for local high school students to showcase their in-depth knowledge of the brain. 56 students from 26 high schools in the Toronto area participated in the competition, including three rounds of questions.

Top 10 Winners

1 Ly Sophia University of Toronto Schools 2 Ravindran Mithunan University of Toronto Schools 3 Ly Olivia University of Toronto Schools 4 Hu Catherine University of Toronto Schools 5 Liu Michael University of Toronto Schools 6 Morris Robert York Memorial Collegiate Institute 6 Qiu Sharon Cardinal Carter Academy for the Arts 6 Zhou Aileen Cardinal Carter Academy for the Arts 9 Egan Shannon University of Toronto Schools 10 Boppana Ujwal University of Toronto Schools

The first place winner, Sophia Ly, represented Toronto at the 6th Annual CIHR Canadian National Brain Bee competition, which took place at McMaster University in Hamilton on June 1, 2013.

Toronto Brain Bee Summer Research Placement The top three winners, Sophia Ly, Mithunan Ravindran and Olivia Ly, were provided summer research placements at the neuroscience researcher’s laboratories. The 2013 summer research placements of the top three Toronto Brain Bee winners are hosted in the laboratories of Morgan Barense (Psychology), Isabelle Aubert (Laboratory Medicine and Pathobiology; Sunnybrook Research Institute), and Zhong-Ping Feng (Physiology).

Toronto Brain Bee Event Brief The students were welcomed by Professor Zhong-Ping Feng (Coordinator of Toronto Brain Bee, Department of Physiology), Professor Steve Matthews (Chair, Department of Physiology), and Ms. Sharon Zillmer (Program Manager, Firefly Foundation). The Brain Bee competition was hosted by Andrew Barszczyk (Graduate student, Physiology) and Danielle DeSouza (Graduate student, IMS). Between the first and second rounds of questions, the students visited the Anatomy Museum at the Division of Anatomy, watched the videos of 2011 Toronto Brain Bee winners and their experience at the University of Toronto (Produced by Firefly Foundation). Three short research presentations were given by Rachel Newsome (Barense lab, Psychology), Catharine Mielnik (Salahpour lab, Pharmacology) and Nancy Dong (Feng lab, Physiology).


2013 Toronto Brain Bee Event Participants

Toronto Brain Bee Organizers

Faculty Chief Judges Jonathan Dostrovsky (TBB advisor, Physiology) Zhong-Ping Fng (TBB coordinator; Physiology) Amy Ramsey (Pharmacology) Ali Salahpour (Pharmacology) Hong-Shuo Sun (Anatomy, Surgery/IMS)

Trainee Volunteers Christine Bae Andrew Barszczyk (TBB

trainee volunteer coordinator) Stephanie Beadman Dr. Jeff Dason Danielle DeSouza Marielle Deurloo Nancy Dong

David Dukoff Melissa Kwan Irene Lecker Jame Li Catharine Mielnik Adma Mosa Rachel Newsome Yi Quan

Sakina Rizvi (TBB High School coordinator) Shannon Roberts Mike Tian Ekaterina Turlova Danielle Weber-Adrian Paul Whissel

Brain Bee Sponsors

The 2013 Brain Bee competition event was co-sponsored by the Department of Physiology and the Firefly Foundation; and supported by the Division of Anatomy. Toronto Brain Bee Registration Toronto Brain Bee Competition 2013 Toronto Brain Bee Organizers The Organizing Committee of the 2013 Toronto Brain Bee Isabelle Aubert (Laboratory Medicine and Pathobiology) Morgan Barense (Psychology) Andrew Barszczyk (Graduate student; Physiology) Jonathan Dostrovsky (Advisor; Physiology) Zhong-Ping Feng (Committee Chair; Physiology) Amy Ramsey (Pharmacology) Ali Salahpour (Pharmacology) Hong-Shuo Sun (IMS/Surgery-Anatomy) Sakina Rizvi (Graduate Student; Pharmaceutical Sciences)


High School Neuroscience Course

The CPIN Graduate Executives Outreach Program coordinator Andrew Barszczyk (Physiology) together with Sakina Rizvi (Pharmaceutical Sciences) organized the Introduction to Neuroscience Course for high school students in the GTA area in 2012-2013. The course not only provided a teaching opportunity for graduate students, but also served as the preparation course for high school students participating 2013 Toronto Brain Bee contest.

Neuroscience Seminars

Neuroscience seminars hosted on the U of T campuses and at affiliated research institutes have been posted on the CPIN website and are updated on a weekly basis. Over 100 seminars have been posted. http://www.neuroscience.utoronto.ca/events /seminar.htm

Neuroscience Conferences and Meetings

Neuroscience-related conferences have been posted on the CPIN website and are updated on a bi-weekly basis. Over 50 local, national, and international conferences have been posted. http://www.neuroscience.utoronto.ca/events/Conf_ M.htm

Date Lecture Time

Monday Dec 03 2012 The Nervous System; The Developing Nervous System 5-6 pm

Monday Dec 10 2012 Neurons and Action Potential; Chemical Messengers 5-6 pm

Monday Dec 17 2012 Touch and Pain; Vision; Dyslexia 5-6 pm

CHRISTMAS BREAK

Monday Jan 7 2013 Sleep; Movement 5-6 pm

Monday Jan 14 2013 Plasticity; Learning and Memory 5-6 pm

EXAM BREAK

Monday Feb 04 2013 Stress; The Immune System 5-6 pm

Monday Feb 11 2013 Drugs and the Brain 5-6 pm

Monday Feb 25 2013 When things go wrong 5-6 pm

Monday Mar 04 2013 Brain Imaging; Neural Networks & Artificial Brains 5-6 pm

MARCH BREAK

Monday Mar 25 2013 Review All Lectures 5-6 pm


CPIN Workshops CPIN Career Workshop – Non-Conventional Careers Date | Monday, June 10, 2013 Time | 9:30 – 11:00 am Location | Room 2172, Medical Sciences Building Speakers | Dr. Christa Studzinski, Senior Program Lead of Research Programs, OBI Dr. Ruslan Dorfman, co-founder, Geneyouin Inc. Dr. Alison Denney, Senor Program Lead fro Industry Relations, OBI

Dr. Philip Caffrey, Public Policy and Programs Analyst, Alzheimer’s Society of Ontario

Dr. Kirk Nylen, Acting Director of Operations and Outreach, OBI Theme | Alternative career options for Neuroscience Graduates Hosts | Janice Robertson & Zhong-Ping Feng, CPIN Research Day Organizing

Committee

CPIN Workshop – Using the Allen Brain Atlas Online Public Resources Date | Wednesday, March 13, 2013 Time | 1:00 – 4:00 pm Speaker | Terri Gilbert, Allen Institute for Brain Science Location | Room 3153, Medical Sciences Building Host | Enoch Ng & Sonia Sugumar Co-sponsors | Department of Physiology, Department of Psychiatry

CPIN Workshops http://www.neuroscience.utoronto.ca/events/2013workshop.htm


Communications and Program Promotion

Website www.neuroscience.utoronto.ca

Updated regularly, the website is the communication hub of the CPIN program. Current and prospective students, faculty members, and other interested parties can use the website to access detailed information about the program including educational activities, membership, community outreach programs, and upcoming seminars, meetings and conferences. Additionally, the website provides links to the monthly newsletter, faculty members and research groups, and offers CPIN application forms for students, postdoctoral fellows, and faculty members.

Email [email protected] The CPIN distribution list includes over 950 subscribers, including member faculty, graduate students, postdoctoral fellows, and University of Toronto Academic Unit leaders. The list is used to share information regarding upcoming academic events, CPIN updates, and the monthly newsletter. The CPIN office also responded inquiries related to the CPIN graduate, postdoctoral and outreach programs on a routine basis.

Newsletters http://www.neuroscience.utoronto.ca/communications/2013newsletter.htm

The CPIN newsletter is distributed via email to the members of the CPIN distribution list, and is posted on the CPIN website. CPIN has produced 6 issues of the newsletter thus far in 2013. The newsletter highlights upcoming events, program news, new faculty members and students, graduating students, and other neuroscience-related activities from across the University and affiliated institutions. Current and past issues of the newsletter can be accessed on the CPIN website. The 2013 newsletters were created and edited by Katie Ferguson, Vlaislav Sekulic and Zhong-Ping Feng.

Facebook https://www.facebook.com/pages/Collaborative-Program-in-neuroscience/ 212564644049 The CPIN Facebook page is used as an alternate forum for communicating information about upcoming events and activities to current graduate students. Students who have liked the Facebook page are invited attend to future academic and social events with their CPIN peers. Like the website, the CPIN Facebook page is updated regularly. Operated by Katie Ferguson, the CPIN Facebook page has currently over 260 users.

CPIN Promotion

To increase the visibility of CPIN and also to support for Canadian graduate programs, CPIN provided a sponsorship to 2013 Canadian Association in Neuroscience Annual Meeting. http://www.can-acn.org/meeting2013/


CPIN Students’ Achievements

Student Awards CPIN attracts and fosters students with outstanding academic achievements. Many CPIN students received and held scholarship and awards in 2012-2013. Examples of student awards are shown in Appendix 6.

Student Publications

CPIN facilitates and promotes research collaboration. Many CPIN students have published peer-reviewed original and/or review articles in peer-reviewed journals during 2012-2013.

Examples of student publications are shown in Appendix 7.

Funding (2012 – 2013) MoA Contributions: CPIN administration was supported by 14 participating

departments from 5 faculties at U of T over the 2012 - 2013 year. Sponsorship: Major CPIN activities were funded by additional contributions from

the MoA participating departments and external sponsors.

The Event Sponsors are listed below:

Distinguished Lectures

Department of Cell and System Biology Department of Physiology CIHR Strategic Training Program in Biological

Therapeutics Music and Health Research Collaboratory (MaHRC),

Faculty of Music Connaught Fund Centre for Addition and Mental Health (CAMH) BRAIN Platform, Department of Physiology Graduate Department of Rehabilitation Science Toronto Western Research Institute (TWRI), UHN Center for Mathematical Medicine (CMM - Fields) Raymond and Beverly Sackler Distinguished Lecture


Workshops

Department of Physiology Department of Psychiatry

Research Day

Faculty of Medicine Department of Anaesthesia Department of Computer Science Department of Laboratory Medicine & Pathobiology Department of Pharmacology & Toxicology Department of Physiology Department of Psychiatry Human Biology Program, Faculty of Arts and Science Mount Sinai Hospital Samuel Lunenfeld Research Institute Olympus Canada Ontario Brain Institute Parkinson Society Canada, Olympus Canada Raymond and Beverly Sackler Foundation Rotman Research Institute, Baycrest Centre SickKids Research Institute Neuroscience & Mental Health St. Michael’s Hospital Toronto Western Research Institute, UHN

Toronto Brain Bee

Department of Physiology Firefly Foundation

The CPIN Financial Report is presented in Appendix 8.


Appendix 1: CPIN Faculty Member Distribution The table and figure below show the distribution of 286 faculty members in each of the MoA participating units. Note: the members who have graduate appointments in more than one unit are only listed in one unit, thus the data may be slightly different from the records in individual units. The data does not include the 55 faculty members from departments that do not participate CPIN MoA.

Academic Unit Number of Faculty Members Biochemistry 5 Cell & Systems Biology 19 Computer Science 2 Dentistry 4 Institute of Biomaterials & Biomedical Engineering 9 Institute of Medical Science 104 Laboratory Medicine & Pathobiology 13 Medical Biophysics 11 OISE 2 Pharmacology & Toxicology 14 Pharmacy 7 Physiology 33 Psychology 47 Rehabilitation Science 16 Total 286

AP

D

BC

M

CS

B

CS

C

DE

D

BM

E

IMS

LMP

MB

P

PH

M

PC

L

PS

L

PS

Y

RE

H


Appendix 2: Current CPIN Students The list is generated according to the records at the CPIN office by June 30, 2013. Surname First Name Degree

Applied Psychology & Human Development

Liu Zhong Xu Ph.D. Saliba Kim Ph.D.

Cell & Systems Biology

Acton Brooke Ph.D.

Augustinavicius Jura Lydia Sarkus M.Sc.

Bond Hilary Clare M.Sc.

Chowdhury Aaron M.Sc.

Curry Tom M.Sc.

de Lannoy Louise M.Sc.

Dukoff David James M.Sc.

Hawrysh Peter John Ph.D.

Lizal Kristin Elisa M.Sc.

Mahadevan Vivek Ph.D.

Pressey Jessica Ph.D.

Ratnam Melanie R Ph.D.

Shams Soaleha Ph.D.

Tran Huy Ngoc Steven M.Sc.

Mahabir Samantha Ph.D.

Dentistry

Awamleh Laith M.Sc.

Pun Henry M.Sc. Institute of Biomaterials & Biomedical

Engineering

Mitrousis Nikolaos Ph.D.

Tuladhar Anup M.A

Zeyl Timothy Ph.D.

Carraro Mattia M.A

Institute of Medical Science Abbasalipour Kabirrah Parvaneh M.Sc.

Abi-Jaoude Elia Ph.D.

Butcher Nancy Jean Ph.D.

Caravaggio Fernando M.Sc.

Cha Danielle Soh-Young M.Sc.

Surname First Name Degree

Cheng Wei-Chin Ph.D.

Deighton Michael Robert M.Sc.

DeSouza Danielle Ph.D.

Dida Joana M.Sc. Elahipanah Ava Ph.D. Emrani Hamideh Ph.D.

Feldcamp Laura Anne Ph.D.

Finkelberg Laura Elizabeth M.Sc.

Fonseka Trehani M.Sc.

Han Hua M.Sc.

Howell Nicholas Araki M.Sc.

Husain Sabah M.Sc.

Jegatheeswaran Gaayathiri Ph.D.

Jiwani Salima Ph.D.

Kentebe Alexandra M.Sc.

Kolla Nathan Ph.D.

Kostelecki Wojciech Ph.D.

Kucyi Aaron Ph.D.

Kumarappah Ananthavalli M.Sc.

Laliberte Alex Michael Ph.D.

Lamba Wiplove M.Sc.

Leeder

Rachel Elizabeth Smart Ph.D.

McCormick Cornelia Ph.D.

McDonald Chloe Elleda Ross Ph.D.

Oh Hyemin M.Sc.

Park Laura SeoHyun M.Sc.

Pereira Robyn Desousa M.Sc.

Raitsin Sofia M.Sc.

Rajendram Rageen M.Sc.

Rajendran Durgaa M.Sc.

Salewski Ryan P Ph.D.

Santoro Adam Ph.D.



Schwindt Graeme Ph.D. Sinopoli Vanessa Ph.D. Soczynska Joanna K Ph.D.

Srejic Luka Ph.D. Sri Renganathan

Sri Dushyaanthan M.Sc.

Steel Morrison Mansour M.Sc.

Szilagyi Gregory Mark M.Sc. Theodoric Nicolas M.Sc.

Tso Michael Kai-Man Ph.D.

Wang Gang M.Sc.

Wang Hsin M.Sc. Whissell Paul David Ph.D.

Wolfe Glenn M.Sc.

Yilmaz Zeynep Ph.D.

Zawadzki John Ph.D.

Isayama Reina M.Sc. Khairullah Nikolaus M.Sc.

Polonenko Melissa M.Sc.

Lowther Chelsea M.Sc.

Chang Michael M.Sc.

Ye Annette M.Sc.

Laboratory Medicine & Pathobiology

Budani Monique M.Sc.

Chiang Helen Yu-Shan Ph.D.

Jordao Jessica Figueira Ph.D.

Macnair Laura Ph.D.

Mehrabian Mohadeseh Ph.D.

Weber-Adrian Danielle M.Sc.

Medical Biophysics Allemang-Grand Rylan M.Sc.

Lake Evelyn Ph.D.

Vousden Dulcie M.Sc.

Molecular Genetics & Microbiology

Mun Ho-suk Ph.D.

Pharmacology

Beerepoot Pieter Claus Ph.D.

Matthews Brittany Ph.D.

Mielnik Catharine Ph.D.

Nona Christina M.Sc.

Rovinski Randal M.Sc.

Bermejo Marie Kristel Ph.D.


Pharmacy

Dong Yue John Ph.D. Gholizadeh Moghaddam Shervin Ph.D.

Rizvi Sakina Ph.D.

Xuan Cong Yang M.Sc.

Physiology

Alim Ishraq Ph.D.

Barszczyk Andrew Ph.D.

Charish Jason Ph.D.

Chen Robert Ph.D.

Cunningham Ceilidh Morgan M.Sc.

Ferguson Katherine A Ph.D.

Florez Carlos Ph.D.

Francis Beverly Ph.D.

Gardezi Syeda Sabiha Ph.D.

Guskjolen Axel Ph.D.

Harding Erika Katharina M.Sc.

Ho Keith Ph.D.

Hutchings Sarah Alexandra M.Sc.

Lam Doris Ph.D.

Lecker Irina Ph.D. Leung Celeste M.Sc.

Liu Jackie Jia M.Sc.

Proulx Eliane Ph.D.

Rozanski Gabriela Maria Ph.D.

Saw Ner Mu Nar Ph.D.

Sekulic Vladislav M.Sc.

Shulyakova Natalya O Ph.D.

Sugumar Sonia Rebecca M.Sc.

Wong Fiona Kar-Mun Ph.D. Wong Raymond YC M.Sc.

Wu Qiu Jing M.Sc.

Xia Frances M.Sc.

Zurek Agnieszka Ph.D.

Mosa Adam M.Sc.

Turlova Ekaterina M.Sc.

Vigouroux Robin M.Sc.

Howard Derek M.Sc. Baello Stephanie Ph.D.

Osipov Denis M.Sc.



Psychology

Amer Tarek Ph.D.

Anderson John Arnold Edward Ph.D.

Bakir Shadi M.A.

Bellicoso Daniela Ph.D.

Dudek Joanna Ph.D. Erez Jonathan Ph.D.

Forster Evelyn Ph.D.

Ghosh Vanessa Elise Ph.D.

Gillingham Susan M Eunice Ph.D.

Glenn Elizabeth Ph.D.

Hughes Jessica Ph.D.

Hutka Stefanie Andrea Ph.D.

Jasinska Kaja Ph.D.

Johnson Sarah Anne Ph.D.

Lee Daniel Hyuk-Joon Ph.D.

Leung Rachel Ph.D.

Man Vincent Yen M.A.

Melo Hans Ludwig Ph.D.

Newsome Rachel Ph.D. Ngo Ka Wai Joan Ph.D.

Surname First Name DegreeSaverino Cristina Ph.D. Shaw Mark M.A. Tanninen Stephanie M.A. Weeks Jennifer Ph.D. Wilkinson Amy Ph.D.

Wong Angelita Pui-Yee Ph.D.

Yeung Lok Kin Ph.D. Arsenault Jessica Ph.D.

Bellana Buddhika Rushmie M.A.

Young Julia Ph.D. Douglas Danielle Ph.D.

Rehabilitation Science Agnihotri Sabrina Ph.D.

Green Stephanie Lynn Ph.D.

Hunt Anne Ph.D. Mollayeva Tatyana Ph.D.

Sage Michael Douglas Ph.D.

Sharma Bhanu M.Sc. Speech-Language Pathology

Flowers Heather Leslie Irene Ph.D.

Shellikeri Sanjana M.Sc.


Appendix 3: CPIN Graduates 2012-2013 Name Degree Supervisor Thesis

Cell & Systems Biology

Peter John Hawrysh

M.Sc.

NMDA Receptor Silencing is Mediated by Calcium Release from the Mitochondria via the Permeability Transition Pore in Anoxia-tolerant Turtle Neurons

Petri Takkala M.Sc. Melanie Woodin Cholinergic Neuromodulation of Activity-dependent Disinhibition-mediated Plasticity

Applied Psychology & Human Development

Steven Woltering Ph.D. Marc Lewis Neural Changes Associated with Treatment Outcome in Children with Externalizing Problems

Kathryn Merrilyn Hum

Ph.D. Marc Lewis The Relationship Between Diet and the Severity of Stuttering in People who Stutter

Institute of Biomaterials & Biomedical Engineering

Ahmed Faress M.A.Sc.

Tom Chau

The Detection of Cognitive Activity within a System-Paced Dual-State Selection Paradigm using a Combination of fNIRS and fTCD Measurements

Institute of Medical Science Maithe Arruda Carvalho

Ph.D. Paul Frankland A Role for Adult Born Neurons in Memory Processing

Nina Bahl M.Sc. Robert Chen Investigation of Neuroplasticity in Parkinson's Disease Patients with Chronic Deep-brain Stimulation

Brian Ballios Ph.D. Derek van der Kooy

New Approaches to the Transplantation of Stem Cells and their Progeny for the Treatment of Retinal Degeneration

Behzad Elahi Ph.D. Robert Chen Paired Associative Plasticity in Human Motor Cortex

Xin Yan Susan Fan

M.Sc. Charles Tator

Effect of Ephrin-B3 on the Survival of Adult Rat Rat Spinal Cord Derived Neural Stem/Progenitor Cells In Vitro and After Transplantation into the Injured Rat Spinal Cord

Sarah Figley Ph.D. Michael Fehlings Delineation of Vascular Disruption and Investigation of a Bioengineered ZFP-VEGF Gene Therapy Following Traumatic Spinal Cord Injury

Matthew Florczynski

M.Sc. Sheena Josselyn The Effects of CREB-mediated BDNF Expression on on Memory- and Anxiety-related Behaviours in the Adult Mouse


Name Degree Supervisor Thesis

Taryn Elizabeth Grieder

Ph.D. Derek van der Kooy

The Involvement of Ventral Tegmental Area Dopamine and CRF Activity in Mediating the Opponent Motivational Effects of Acute and Chronic Nicotine

Ammar Khairullah M.Sc. Tomas Paus Timing and Dynamics of Sexual Maturation in Males Predicts White Matter Properties in Late Adolescence

Dionne Elise Laslo-Baker

Ph.D. Joanne Rovet Child Neurodevelopment Following In Utero Exposure to Organic Solvents

Yao Lin M.Sc. Margot Taylor FMRI of a Visual Patterns N-back Task in Typical Development

Alonso Martinez Canabal

Ph.D. Paul Frankland

The Denate Gyrus of the Hippocampus: Roles of Transforming Growth Factor beta 1 (TGFb1) and Adult Neurogenesis in the Expression of Spatial Memory

Massieh Moayedi Ph.D. Karen Davis Structural Brain Abnormalities in Temporomandibular Disorders

Allison Needham M.Sc. Paul Sandor Processing of Tactile Stimuli in Children with Tourette Syndrome and Attention Deficit Hyperactivity Disorder: An ERP Investigation

Rana Arham Raashid

M.Sc. Agnes Wong Short-term Saccadic Adaptation in Patients with Amblyopia

Meghna Rajaprakash

M.Sc. Joanne Rovet Cortical Morphology in Children with Alcohol- related Neurodevelopmental Disorder

Joel Roy Ramirez Ph.D. Sandra Black Subcortial Hypertensities in Alzheimer's Disease and the Elderly: An MRI-based Study Examining Signs of Cerebrovascular Disease and Dementia

Allison Victoria Rosen

M.Sc. Mojgan Hodaie Non-Invasive 3D Visualization and Thickness Analysis of the Human Insula

Wylie Tan M.Sc. Carol Westall Localizing Structural and Functional Damage in the Neural Retina of Adolescents with Type 1 Diabetes

Sinthujah Varatharajah

M.Sc. Margot Taylor Inhibition in Adolescents and Adults with Autism Spectrum Disorders (ASD)

Gang Wang M.Sc. Karen Davis Sex Differences in the Connectivity of the Subgenual Anterio Cingulate Cortex: Implications for Pain Habituation

Patrick Yoo M.Sc. Karen A. Gordon Source Analysis of Cortical Responses at Initial Cochlear Implant use in Children_who are Deaf

Sepehr Ehsani Ph.D. Gerold Schmitt-Ulms

The Significance of the Evolutionary Relationship of Prion Proteins and ZIP Transporters in Health and Disease

Medical Biophysics Kristen Patricia Fortney

Ph.D. Doug Tweed

Patrick Steadman MSc Jason Lerch


Pharmacology & Toxicology

Sarah Chau M.Sc. Krista Lanctôt

Effect of Methylphenidate on Attention in Apathetic Alzheimers Disease Patients and Association with Apathy Changes in a Randomized, Placebo-controlled Trial

Meaghan Claire Creed

Ph.D. Jose Nobrega Deep Brain Stimulation of the Subthalamic and Entopeduncular Nuclei in an Animal Model of Tardive Dyskinesia

Graham Mazereeuw

M.Sc. Krista Lanctôt Platelet Activating Factors and Depressive Symptoms in Coronary Artery Disease Patients

Angela Roedding Ph.D. Jerry Warsh Effects of Chronic Oxidative Stress on TRPM2 and TRPC3 Channels: Potential Implications for Bipolar Disorder

Pharmacy

Sofia Huroy M.Sc. Jeffrey Henderson

Mechanisms of EphB2 Mediated Opiate-dependent Tolerance and Learning

Physiology

Tanya Alves M.Sc. Lu-Yang Wang NMDAR-dependent Synaptic Plasticity at the Calyx of Held Synapse

Lulu Gao M.Sc. J Martin Wojtowicz

Animal Models of Alzheimers Disease, Stroke, Type II Diabetes Co-morbidity: The Role of Hippocampal Adult Neurogenesis

Tom Ziming Lu Ph.D. Zhong-Ping Feng Sodium Leak Current through a Non-selective Cation Channel Regulates Spontaneous Activity of Pacemaker Cells

Nasrin Nejatbakhsh

Ph.D. Zhong-Ping Feng Characterization of a Novel Growth-promoting Invertebrate Gene in Central Neurons

Yi Quan M.Sc. Zhong-Ping Feng NCS-1 Protein Upregulation Facilitates Chronic Hypoxia-induced Respiratory Adaptation in Lymnaea stagnalis

Melanie Jay Sekeres

Ph.D. Sheena Josselyn CREB-mediated Enhancement of Hippocampus-dependent Memory Consolidation and Reconsolidation

Zarko Todorovski Ph.D. Zheng-Ping Jia LIMK1 Regulation of Long-term Memory and Synaptic Plasticity

Psychology

Alexander James Barnett

M.A. N/A

Memory Functioning in Patients with Unilateral Temporal Lobe Epilepsy: Neuroimaging Indicators of Functional Integrity in the Hippocampus and Beyond

James Donald Caleb Browne

M.A. Paul Fletcher

Acquisition and Responding for Conditioned Reinforcement in the Mouse: Effects of Methylphenidate, and the Role of the Dopamine Transporter


Christie Burton Ph.D. Paul Fletcher

Examination of Age Differences in Impulsivity and Incentive Motivation as Possible Contributing Factors to a Susceptibility to the Effects of Drugs of Abuse during Adolescence

Danielle Douglas M.A. Morgan Barense Investigating the Boundaries of Feature Conjunction Representations in the Perirhinal Cortex

Nicole Law Ph.D. David Mabbott N/A

Rachel Leung M.A. Margot Taylor Neural Activation During Emotional Face Processing in Adolescents with Autism Spectrum Disorders

Robin Nguyen M.A. Kim Junchal Role Of The Ventral Hippocampus in Exploratory Locomotion and Ventral Hippocampal Parvalbumin Neurons in Schizophrenia

Taylor Schmitz Ph.D. Adam Anderson/Eve De Rosa

Attentional Filtering in Young and Older Adulthood

Dominique Thy An Vuvan

Ph.D. Mark Schmuckler The Statistical Learning of Musical Expectancy


Appendix 4: Neuroscience Course List Neuroscience courses offered by the participating units are listed below. Not all courses are offered each year.

DEN 1060H Oral Physiology: Sensory and Neuromuscular Function HDP 1238H Special Topics in Human Development & Applied Psychology: Neuroscience &

Education: Bridging the Gap HDP 3286H Developmental Neurobiology JEB 1444H Neural Engineering JEB 1451H Neural Bioelectricity JNR 1444Y Fundamentals of Neuroscience: Cellular and Molecular JNS 1000Y Fundamentals of Neuroscience: Systems and Behaviour JPM 1005Y Behavioural Pharmacology JPY 1007Y Neuropharmacology of Neurotransmitter Receptors JYG 1555H Topics in Cellular and Molecular Neurobiology MSC 1006H Advanced Neuroanatomy MSC 1081H Studies in Schizophrenia MSC 1085H Molecular Approaches to Mental Health and Addictions MSC 1086H Integrative perspectives in Consciousness and Self-Awareness MSC 1087H Neuroimaging Methods Using Magnetic Resonance Imaging MSC 1088H Brain Positron Emission Tomography MSC 6000H Special Topics in Anatomy PCL 1012H Cognitive Neuropharmacology PSL 1024H Advanced Topics: Endocrinology and Neuroendocrinology PSL 1026H Advanced Topics: Experimental Cell Physiology PSL 1047H Advanced Topics: Somatosensory and Pain Neuroscience PSL 1050H Advanced Topics: The Hippocampus from Cell to Behaviour PSL 1053H Advanced Topics: Critical Assessment of Ion Channel Function PSL 1068H Advanced Topics: Molecular Basis of Behaviour PSL 1071H Advanced Topics: Computational Neuroscience PSL 1075H Biology In Time PSL 1441H Systems Level Neuroplasticity PSL 1445H Mechanistic Molecular & Cellular Neuroscience PSL 1446H Molecular & Cellular Aspects of Neural Disorders PSL 1452H Fundamentals of Ion Channel Function PSY 4706H Human Brain Neuroanatomy PSY 5101H Mechanisms of Behaviour PSY 5103H Learning and Plasticity PSY 5104H Neuropsychology PSY 5110H Advanced Topics in Behavioural Neuroscience I PSY 5111H Advanced Topics in Behavioural Neuroscience II PSY 5112H Advanced Topics in Behavioural Neuroscience III PSY 5120H Advanced Topics in Animal Behaviour and Motivation I


PSY 5121H Advanced Topics in Animal Behaviour and Motivation II PSY 5130H Advanced Topics in Neuropsychology I PSY 5131H Advanced Topics in Neuropsychology II PSY 5132H Advanced Topics in Neuropsychology III PSY 5201H Audition PSY 5202H Vision PSY 5203H Higher Cognition PSY 5204H Attention PSY 5205H Memory PSY 5210H Advanced Topics in Perception I PSY 5211H Advanced Topics in Perception II PSY 5212H Advanced Topics in Perception III PSY 5220H Advanced Topics in Cognition I PSY 5221H Advanced Topics in Cognition II PSY 5222H Advanced Topics in Cognition III PSY 5310H Advanced Topics in Development I PSY 5311H Advanced Topics in Developmental Neuroscience II REH 1510H Disordered Restorative Motor Control REH 5100H Introduction to Cognitive Rehabilitation Neuroscience I: Basic Science to Clinical

Applications REH 5102H Cognitive Rehabilitation Neuroscience II

Other Courses

Courses not specifically in neuroscience, that do not fulfil the program requirements as neuroscience courses, but might be useful for neuroscience students, are listed below.

JBL 1507H Biochemistry of Inherited Disease JDB 1025Y Developmental Biology JNP 1017H+ The Molecular and Biochemical Basis of Toxicology JNP 1018H+ Current Topics in Molecular and Biochemical Toxicology PHM 1122H Fundamentals of Drug Discovery PSY 5102H Motivational Processes SLP 1522Y Speech Physiology and Acoustics SLP 1533Y Aphasia SLP 1534Y Motor Speech Disorders SLP 3001H Theoretical Foundations of Communication Sciences + Extended course. For academic reasons, coursework is extended into session following academic session

in which course is offered.


Appendix 5: Distinguished Lectureship Survey Statistics

Student Feedback


Feedback from students for Lectures X, Y, and Z:


Appendix 6: Student Awards Student Name Awards Year

Parvaneh Abbasalipour Kabirrah

SGS Conference Grant

University of Toronto School of Graduate Studies Conference Grant 2013 Elia Abi-Jaoude

Harvey Stance Research Day Best Presentation by a Fellow 2012 CIHR Brain Star Award 2012

Brooke Acton Vanier CGS-D Award Peterborough K.M. Hunter Graduate Studentship Ontario Graduate Scholarship Pieter Beerepoot FRIST-JUS Annual Memorial Award in Neuropsychopharmacology Brain Canada Mental Health Training Award

Nancy Butcher Parkinson Society Canada Graduate Student Award (declined)

Alan Wu Poster Competition Award Recipient (1st Place, Clinical Research), Institute of Medical Science Scientific Day

Poster Competition Award Recipient (3rd place), Toronto Western Research Institute, UHN

Ontario Graduate Scholarship, Ministry of Training, Colleges and Universities

University of Toronto Centre for the Study of Pain (UTSCP) Pain Scientist Scholarship, U of T Faculty of Medicine

James F. Crothers Family Fellowships in Peripheral Nerve Damage OSTF Award, U of T Faculty of Medicine

Institute of Medical Science Open Fellowship Award, U of T, Faculty of Medicine

CIHR Cell Signals Strategic Training Fellowship, Canadian Institutes of Health Research

Unilever/Lipton Graduate Fellowsihp in Neuroscience, U of T, Faculty of Medicine Office of Research Trainees Conference Travel Award, UHN

Danielle DeSouza

School of Graduate Studies Conference Grant, U of T, SGS J. Davidson Ketchum Graduate Scholarship in Psychology 2012-2013 SGS Conference Grant 2012-2013 Early Researcher Award, Ontario Research Coalition 2012-2013

Vanessa Ghosh

Jack and Rita Catherall Fund for Travel 2012

Erika Harding UTCSP Pain Scientist Trainee Award - University of Toronto Centre for the Study of Pain Ontario Graduate Scholarship 2013 Wiseman Graduate Studentship 2013 SGS Conference Grant 2012

Stefanie Hutka

Jack and Rita Catherall Fund for Travel 2012


Aaron Kucyi CIHR Doctoral Award Nick Mitrousis IBBME International Scholar's Program Tatyana Mollayeva Frederick Banting and Charles Best Scholarship - CIHR 2013 Ho-Suk Mun Ontario Graduate Scholarship

Rachel Newsome U of T Faculty of Arts & Science Travel Award to Society for Neuroscience Conference Julie Payette NSERC Research Scholarship

Christina Nona Andre Hamer Postgraduate Prize Heart & Stroke Foundation Doctoral Research Award 2010-2013 Peterborough K.M. Hunter Graduate Studentship 2012-2013 Michael Sage

Toronto Rehabilitation Institute Student Scholarship 2012-2013 Sanjana Shellikeri SGS Conference Grant

Vanier Canada Graduate Scholarship 2013-2016

Neurosurgery Research & Education Foundation Cerebrovascular Section Research Fellow 2013-2014 Canadian Institute of Heath Research Fellowship (declined) 2013-2016 Bisby Fellowship Award (declined) 2013-2016 Canadian Stroke Network Travel Award 2013

Michael Tso

University of Toronto School of Graduate Studies Conference Grant 2013

Ekaterina Turlova CIHR Master's Award 2013

Toronto Western Research Institute Research Day - podium presentation award (3rd place) Gang Wang

Mountain Sinai Hospital Volunteer Award Amy Wilkinson Studentship Award - Ontario Neurotrauma Foundation 2012

Ontario Graduate Scholarship, U of T Hospital for Sick Children Student Scholarship (Resttracomp) Frances Xia QEII-GSST Purdue Pharma Award - Queen Elizabeth the Second Graduate Scholarships in Science and Technology

Ontario Graduate Scholarship. Ontario Ministry of Training, Colleges and Universities 2011-2012

University of Toronto, Institute of Medical Science Open Fellowship Award 2012 University of Toronto, School of Graduate Studies Conference Grant 2012

John Zawadzki

University of Toronto Fellowship – Institute of Medical Science. 2012

(Note: The list was generated based on the information in the current records at the CPIN office)


Appendix 7: Student Publications

Student Name Publications Sasich L and Abi-Jaoude E. (2013) Re: Are clinical trial data shared sufficiently today? No, [eLetter] BMJ, published online July 15, 2013

Gorman D. and Abi-Jaoude E. Managing attention-deficit/hyperactivity disorder, Canadian Medical Association Journal June 24, 2013 (On-line).Doshi P., Abi-Jaoude E., Lexchin J., Jefferson T., Thomas R.E. (2013) Influenza vaccination of health care workers, Canadian Medical Association Journal, 185, 150.

Abi-Jaoude E. and Gorman D. (2013) Tourette Syndrome, Canadian Medical Association Journal, 185, 236.

Elia Abi-Jaoude

Gorman D. and Abi-Jaoude E. (2012) Commentary on ‘Pharmacological Treatment for Attention Deficit Hyperactivity Disorder (ADHD) in Children with Comorbid Tic Disorders’, Evidence-Based Child Health, 7, 1231 – 1234. Ivakine EA*, Acton BA*, Mahadevan V*, Ormond J, Tang M, Pressey JC, Huang MY, Ng D, Delpire E, Salter MW, Woodin MA, McInnes RR. Neto2 is a KCC2 interacting protein required for neuronal Cl- regulation in hippocampal neurons. (* indicates equal contributions) Proc Natl Acad Sci U S A. 2013;110(9):3561-6. Brooke Acton Acton, B.A., Mahadevan, V., Mercado, A., Uvarov, P., Ding, Y., Pressey, J., Airaksinen M.S., Mount, D.B., and Woodin, M.A. (2012). Hyperpolarizing GABAergic Transmission Requires the KCC2 C-terminal ISO Domain. J Neurosci 32(25):8746-51.

Mila Aleksic Aleksic M, Feng Z.-P (2012) Identification of the role of C/EBP in neurite regeneration following microarray analysis of a L. stagnalis CNS injury model. BMC Neurosci. 13(1):2. Lam V*, Beerepoot P*, Angers S, Salahpour A (2013) Development of a new assay for quantitative measurement of surface expression of membrane proteins Traffic. 14(7):778-784

Pieter Beerepoot Beerepoot P, Lam VM, Salahpour A. (2013) Measurement of G protein-coupled receptor surface expression. J Recept Signal Transduct Res. 33(3):162-165

Nancy Butcher Butcher NJ, Chow EWC, Costain G, Karas D, Ho A, Bassett AS. 2012. Functional outcomes of adults with 22q11.2 deletion syndrome. Genetics in Medicine. 14:836-843.

Robert Chen

Chen R.H., Wislet-Gendebien S., Samuel F., Visanji N.P., Zhang G., Marsilio D., Langman T., Fraser P.E., Tandon A. (2013) α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity. J Biol Chem 288(11): 7438-49

Danielle DeSouza

DeSouza DD, Moayedi M, Chen DQ, Davis KD, Hodaie M. (2013). Sensorimotor and Pain Modulation Abnormalities in Trigeminal Neuralgia: a Paroxysmal, Sensory-Triggered Neuropathic Pain. PLoS ONE, 8(6): e66340.

Beverly Francis

Francis BM, Yang J, Hajderi E, Brown ME, Michalski B, McLaurin J, Fahnestock M, Mount HTJ (2012) Reduced tissue levels of noradrenaline are associated with behavioural phenotypes of the TgCRND8 mouse model of Alzheimer’s disease. Neuropsychopharmacology, 37(8):1934-44.


Hutka, S., Binns, M., Bidelman, G. M., & Alain, C. (2013). Age-related differences in the perceptual organization of speech sounds. Journal of the Acoustical Society of America. 133(6):4177-87. Bidelman, G. M., Hutka, S., & Moreno, S. (2013). Tone language speakers and musicians share enhanced perceptual and cognitive abilities for musical pitch: Evidence for bidirectionality between the domains of language and music. PLOS ONE, 8(4), e60676.

Stefanie Hutka

Alain, C., Bidelman, G. M., Hutka, S., & Zendel, B. R. (In press). The benefit of musical training on the aging auditory brain. Hearing Research. (HEARES-D- 13-00020.)

Jessica Jordao

Jordão J.F., Thévenot E., Markham-Coultes K., Scarcelli T., Weng Y.-Q., Xhima K., O’Reilly M., Huang Y., McLaurin, J., Hynynen K., Aubert I. Amyloid-ß plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound. Experimental Neurology. 2013 May 21;248C:16-29. Kucyi, A., Hodaie, M., Davis, K.D (2012). Lateralization in intrinsic functional connectivity of the temporoparietal junction with salience- and attention-related brain networks. Journal of Neurophysiology 108(12):3382-92.

Aaron Kucyi Kucyi, A., Moayedi, M., Weissman-Fogel, I., Hodaie, M., Davis, K.D (2012). Hemispheric asymmetry in white matter connectivity of the temporoparietal junction with the insula and prefrontal cortex. PLoS One 7(4):e35589.

Chelsea Lowther

Costain G, Lionel AC, Merico D, Forsythe P, Russell K, Lowther C, Yuen T, Husted J, Stavropolulos DJ, Speevak M, Chow EW, Marshall CR, Scherer SW, Bassett AS. Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays. Human Molecular Genetics, June 27, 2013 (online publication). Ivakine EA*, Acton BA*, Mahadevan V*, Ormond J, Tang M, Pressey JC, Huang MY, Ng D, Delpire E, Salter MW, Woodin MA, McInnes RR. Neto2 is a KCC2 interacting protein required for neuronal Cl- regulation in hippocampal neurons. (* indicates equal contributions) Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3561-6.

Tang M, Ivakine E, Mahadevan V, Salter MW, McInnes RR. Neto2 interacts with the scaffolding protein GRIP and regulates synaptic abundance of kainate receptors. PLoS One. 2012;7(12):e51433. Sekeres MJ, Mercaldo V, Richards B, Sargin D, Mahadevan V, Woodin MA, Frankland PW, Josselyn SA. Increasing CRTC1 function in the dentate gyrus during memory formation or reactivation increases memory strength without compromising memory quality.J Neurosci. 2012 Dec 5;32(49):17857-68.

Vivek Mahadevan

Acton BA, Mahadevan V, Mercado A, Uvarov P, Ding Y, Pressey J, Airaksinen MS, Mount DB, Woodin MA. Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain. J Neurosci. 2012 Jun 20;32(25):8746-51. Martinez-Canabal A, Wheeler AL, Sarkis D, Lerch JP, Lu WY, Buckwalter MS, Wyss-Coray T, Josselyn SA, Frankland PW. Chronic over-expression of TGFβ1 alters hippocampal structure and causes learning deficits. Hippocampus. 2013 Jun 27. doi: 10.1002/hipo.22159. [Epub ahead of print]

Alonso Martinez Canabal

Martinez-Canabal A, Akers KG, Josselyn SA, Frankland PW. Age-dependent effects of hippocampal neurogenesis suppression on spatial learning. Hippocampus. 2013 Jan;23(1):66-74.


Mollayeva T, Kendzerka T, Mollayeva S, Colantonio A. Sleep Apnea in Traumatic Brain Injury: Understanding Its Impact on Executive Function.Journal of Sleep Disorders & Therapy/accepted July 19,2013 Mollayeva T, Colantonio A, Mollayeva S, Shapiro CM. Screening for Sleep Dysfunction after Traumatic Brain Injury. Sleep Medicine/accepted July 15, 2013 Mollayeva, T., Kendzerska, T., Mollayeva, S., Shapiro, C., Colantonio, A., & Cassidy, J. D. (2013). Fatigue in adults with traumatic brain injury: predictors and consequences: a systematic review of longitudinal study protocols. Systematic Reviews, 2(1), 57 Mollayeva, T., Kendzerska, T., & Colantonio A. Self-report instruments for assessing sleep dysfunction in traumatic brain injury population: A systematic review. Sleep Medicine Reviews. 2013 Epub ahead of print. [abstract] Kendzerska, T., Mollayeva, T., Gershon, A., Leung, R., Hawker, G., & Tomlinson, G.. Untreated obstructive sleep apnea: A systematic review of the risks for serious adverse outcomes. Sleep Medicine Reviews. 2013 Epub ahead of print. [abstract]

Tatyana Mollayeva

Kim, H., Bayley, M., Dawson, D., Mollayeva, T., & Colantonio, A. Characteristics and functional outcomes of brain injury caused by physical assault in Canada: A population-based study from an inpatient rehabilitation setting. Disability & Rehabilitation. 2013; Epub ahead of print. [abstract] Duarte, A., Hearons, P., Jiang, Y., Delvin, M.C., Newsome, R.N., and Verhaeghen, P. (2013). Retrospective attention enhances visual working memory in the young, but not the old: an ERP study. Psychophysiology.

Newsome, R.N., Dulas, M.R. and Duarte, A. (2012). The effects of aging on emotion induced modulations of source retrieval ERPs: Evidence for valence biases. Neuropsychologia, 50: 3370-3384.

Rachel Newsome

Newsome, R.N., Duarte, A., and Barense, M.D. (2012). Reducing perceptual interference improves discrimination performance in mild cognitive impairment patients. Hippocampus, 22: 1990-1999.

Christina Nona

Nona, C. N., Guirgus, S., Nobrega, J.N. (2013). "Susceptibility to ethanol sensitization is differentially associated with changes in pCREB, trkB and BDNF mRNA expression in the mouse brain." Behavioural Brain Research 242(1): 25-33

Michael Sage

Sage, M.D., Middleton, L.E., Tang, A., Sibley, K., Brooks, D., McIlroy, W. (2013). Validity of perceived exertion ranges in individuals in inpatient stroke rehabilitation. Topics in Stroke Rehabilitation. IN PRESS (January 27, 2013)

Cusimano MD, Sharma B, Lawrence DW, Ilie G, Silverberg S, Jones R. Trends in North American newspaper reporting of brain injury in ice hockey. PLoS One. 2013 Apr 17;8(4):e61865. Bhanu Sharma Sharma B, Cusimano MA. Will New Legislation Aimed at Preventing Concussions in Youth Succeed? Injury Prevention. 2013 (Accepted) Jul 23.

Sanjana Shellikeri Shellikeri, S, Yunusova, Y, Thomas, D, Green, J, & Zinman, L. 2013. Compensatory articulation in amyotrophic lateral sclerosis: tongue and jaw in speech, Proceedings of meetings on acoustics 19, 060061.

Steven Tran Tran, S. & Gerlai, R. (2013). Time-course of behavioural changes induced by ethanol in zebrafish (Daniorerio). Behavioural Brain Research, 252, 204 - 213


Tso MK, and RL Macdonald. Acute Microvascular Changes after Subarachnoid Hemorrhage and Transient Global Cerebral Ischemia. Stroke Research and Treatment. 2013 425281:1-9.

Michael Tso Tso M, and RL Macdonald. Perspective: A Need for a Standardized Cognitive Outcome Measure in Subarachnoid Hemorrhage Clinical Trials. World Neurosurgery. 2013. PMID 23507296.

Ekaterina Turlova Turlova, E. and Feng, ZP. (2013) Dietary salt intake and stroke. Acta Pharmacologica Sinica. 34(1): 8-9 Zawadzki, J.A.; Woodward, T.S.; Sokolowski, H.M.; Boon, H.S.; Wong, A.H.C.; Menon, M. (2012). Cognitive factors associated with subclinical delusional ideation in the general population. Psychiatry Research. 197, 345 – 349. DOI:10.1016/j.psychres.2012.01.004. Menon, M.; Quilty, L.C.; Zawadzki, J.A.; Woodward, T.S.; Sokolowski, H.M.; Boon, H.S.; Wong, A.H.C. (2012). The role of cognitive biases and personality variables in subclinical delusional ideation. Cognitive Neuropsychiatry. DOI:10.1080/13546805.2012.692873. PMID: 22758619 Zawadzki, J.A.; Foussias, G.; Rodrigues, A.; Siddiqui, I.; Lerch, J.; Girard, T.A.; Grady, C.; Remington, G.; Wong, A.H.C. (2013). Spatial Navigation in Schizophrenia Using a Realistic Virtual City. Schizophrenia Bulletin. 39 (S1):S254.

John Zawadzki

George Foussias, I Siddiqui, K McDonald, N Hasan, S Thavabalasingam, C Plagiannakos, J Zawadzki, K K Zakzanis, P Fletcher, A Wong, Gary Remington (2013). Evaluating Motivation in Schizophrenia in a Virtual Environment: A Novel Objective Assessment Methodology. Schizophrenia Bulletin. 39 (S1):S229.

(Note: The list was generated based on the information in the current records at the CPIN office)


Appendix 8: Financial Report

The Financial Report includes the program administrative and event activities from November 15, 2013 to June 30, 2013. REVENUES Category Amount ($)

Carry forward from 2011-2012 4,933 Participating Dept Contributions 36,000 Sponsorship (Cash) 6,770

Sponsorship (In-Kind; Distinguished CPIN Lectures) 11,987

TOTAL 59,690

EXPENDITURES Category Amount ($)

Administrative Operation* 3,525 Administration: Salary and Benefits 22,983 CPIN events/activities 20,863

Student Awards 2,100

TOTAL 49,471*includes telephone, website fee, office supplies, set-up service fee, etc.

Carry-forward 2013-2014 10,219

2012 – 2013 Annual Report Published by Collaborative Program in Neuroscience (CPIN) University of Toronto July 2013 Editors Elissa Caccavella, B.A.Sc., M.Eng. Zhong‐Ping Feng, M.D., Ph.D. FitzGerald Building, Rm 83E 150 College Street Toronto, ON M5S 3E2 http://www.neuroscience.utoronto.ca/ p.neuroscience@utoronto



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