Cognitive Research & Cognitive Research & NCMRRNCMRR

Michael Weinrich, M.D.

Director, National Center for Medical Rehabilitation Research

NICHD, NIH

Bethesda, MD

mw287K@nih.gov

NCMRRNCMRR

Established 1990 PL 101-613Center within NICHDAdvisory BoardResearch Plan 1993Rehab Coordinating CommitteeFunds research, training & SBIR

NCMRR Systems ApproachNCMRR Systems Approach

Patho-physiology Impairment

Functional Limitation

Disability Societal Limitation

Research Plan: Areas of Research Plan: Areas of EmphasisEmphasis

Mobility Behavioral Adaptation Whole Body Response Assistive

Technologies

Measurement, Assessment & Epidemiology

Treatment Effectiveness

Training Rehabilitation Scientists

October 1998

http://www.nichd.nih.gov/publications/pubs/traumatic/Abstracts.htm

http://odp.od.nih.gov/consensus/cons/109/109_statement.htm

AHCPR AHCPR Evidence-Based Practice Evidence-Based Practice

ReportReport 1.Should interdisciplinary rehabilitation begin during acute hospitalization for TBI?

2.Does the intensity of inpatient interdisciplinary rehabilitation affect long-term outcomes?

3.Does the application of cognitive rehabilitation enhance outcomes for persons who sustain TBI?

4.Does the application of supportive employment enhance outcomes for persons with TBI?

5.Does the provision of long-term care coordination enhance the general functional status of persons with TBI?

Needs in Cognitive Needs in Cognitive Rehabilitation ResearchRehabilitation Research

Establish and evidence base for clinical practice

Incorporate knowledge from experimental psychology: errorless learning, imagery, etc.

Adopt new technologies: adaptive learning, VR, multi-modal presentation, cueing strategies, etc.

Range of Current Research Range of Current Research on Cognition Supported by on Cognition Supported by

NCMRRNCMRRCognitive Rehabilitation for TBI“Talking Lights”fMRI & EP especially in recoveryVR and drivingRehabilitation of cognitive symptoms in MSCognitive rehabilitation--acquired dyslexiaProblem solving in acquired brain damage

RFA: RFA-HD-01-007RFA: RFA-HD-01-007

Data Safety Monitoring Board

Clinical Site Clinical Site Clinical Site Clinical Site Clinical Site

Data Coordinating Center NCMRR

COOPERATIVE MULTICENTER TRAUMATIC BRAIN INJURY CLINICAL TRIALS NETWORKRelease Date: March 26, 2001

RFA: HD-00-016RFA: HD-00-016

INNOVATIVE REHABILITATION INTERVENTIONS

Release Date: June 27, 2000

54 Applications received

CLINICAL TRIAL PLANNING GRANTS TO GUIDE TIMING, INTENSITY, AND DURATION OF

REHABILITATION FOR STROKE AND HIP FRACTURE

Release Date: September 20, 2001

RFA: RFA-HD-01-022

Letter of Intent Receipt Date: January 18, 2002

Application Receipt Date: February 14, 2002

ALTERNATIVE AND ALTERNATIVE COMMUNICATION STRATEGIES FOR TREATMENT OF COGNITIVE-LINGUISTIC DISORDERS   Letter of Intent Receipt Date: February 2002 (30 days prior to submission date)   Application Receipt Date: March 2002

NCMRRNCMRR

Behavioral Sciences and Rehabilitation Engineering (SBIR)

Biological Sciences and Career Development

Clinical Practices Program

Lou Quatrano, PhD 301-402-4221 lq2n@nih.gov

Ralph Nitkin, PhD 301-402-4206 rn21e@nih.gov

Beth Ansel, PhD 301-496-5289 anselb@mail.nih.gov