cns hemorrhages
DESCRIPTION
CNS HEMORRHAGES. Rohit Mathew Roy MD-4 1046. Hemorrhage is loss of blood from the blood vessels This could be internally (blood leaks from a blood vessel inside the body) or externally (through nose, mouth, ear etc ) General Facts : - PowerPoint PPT PresentationTRANSCRIPT
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Rohit Mathew RoyMD-41046
CNS HEMORRHAGES
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Hemorrhage is loss of blood from the blood vessels
This could be internally (blood leaks from a blood vessel inside the body) or externally (through nose, mouth, ear etc)
General Facts: - Hemorrhage is responsible for 35% of Pre-Hospital Deaths and about 40% of deaths in the first 24 hours - Arterial – Bright Red Blood Venous – Dark Red Capillary – Brick Red - General Hemorrhage classified on basis of severity
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Head TraumaHigh Blood PressureAneurysmsBlood Vessel AbnormalitiesBlood or Bleeding DisordersBrain TumorsLiver DiseaseAmyloid Angiopathy
Causes
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Severe HeadacheSeizuresWeakness in an arm or legNausea or VomitingLethargy and Decreased AlertnessDifficulty performing basic functions (like
swallowing, reading and writing, speech)Hand tremors and loss of balanceNumbness and TinglingBlurred Vision
Symptoms
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Intra-Axial Hemorrhage – Bleeding within the Brain itself. This category includes:
- Intraparenchymal Hemorrhage 1. Basal Ganglia Hemorrhage 2. Pontine Hemorrhage 3. Cerebellar Hemorrhage 4. Lobar Hemorrhage - Intraventricular HemorrhageExtra-Axial Hemorrhage – Occurs within the skull
but outside the Brain tissue. There are 3 subtypes: - Epidural Hemorrhage - Subdural Hemorrhage - Subarachnoid Hemorrhage
Classifications
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Bleeding within brain parenchyma
Subdivided on the basis of Location: - Basal Ganglia Hemorrhage - Pontine Hemorrhage Hypertensive - Cerebellar Hemorrhage
- Lobar Hemorrhage - Cerebral Amyloid Angiopathy
Underlying Pathology for Hypertensive Intraparenchymal Hemorrhage is Charcot-Bouchard Aneurysm
Intraparenchymal Hemorrhage
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BASAL GANGLIAHEMORRHAGE
PONTINE HEMORRHAGE
CEREBELLAR HEMORRHAGE
CAUSEPoorly Controlled Long Standing Hypertension (80%)
Poorly Controlled Hypertension (Poor Prognosis) (10%)
Poorly Controlled Hypertension but Can be secondary to underlying lesion (tumor or vascular ) (10%)
PATHOLOGYMicroaneurysms of Perforating Arteries (lenticulo-strait vessels), Atherosclerosis
Penetrating arteries from basilar artery extending to pons prone to rupture (Larger Paramedian Perforators)
Perforating Vessels
SYMPTOMS
Loss of consciousness, Headaches, Nausea, Vomiting, Seizures
Decreased Consciousness, Tetraparesis, Seizures, Cheyne-Stokes Respiration
Ataxia, Nystagmus, Impaired Consciousness, Obstructive Hydrocephalus
ADDITIONAL INFORMATION
Common location is the Putamen (contralateral hemiplegia, hemianesthesia and hemianopia)
Secondary causes involve tumor, vascular malformations, downward herniation and supratentorial surgery
Good Prognosis,Secondary cause involves tumor, supratentorial surgery
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Basal Ganglia Hemorrhage (80%)
Pontine Hemorrhage (10%)
Cerebellar Hemorrhage (10%)
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Large, Located Superficially within the Cerebral Hemispheres
Commonly seen in Elderly PatientsSuperficial location make them prone to extend into
the subdural space (less commonly can also extend into the intraventricular system)
Underlying Pathology: Cerebral Amyloid Angiopathy: Amyloid Deposits seen on the walls of the vessels
Can also be associated with underlying lesions like Cerebral Arteriovenous Malformation, Cerebral or Venous Infarct and Underlying tumors.
Patients present with acute neurological deterioration (Decreased GCS). Headache may be present.
Lobar Hemorrhage
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Lobar Hemorrhage
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Denotes presence of blood within the ventricular system of the brain (can cause dev. of obstructive hydrocephalus)
Primary (blood in ventricle and little parenchymal blood) and Secondary (large extraventricular component within extension into ventricles) Types
Primary: Caused by Intraventricular Tumors, Vascular Malformations
Secondary: Intracerebral hemorrhage and Subarachnoid Hemorrhage
Clinical Presentation similar to subarachnoid hemorrhage. Severe Headache, Signs of Meningism (Photophobia, nausea, vomiting, neck stiffness), Loss of Consciousness, Seizures, Brainstem compression with Cardiorespiratory Compromise
Intraventricular Hemorrhage
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Intraventricular Hemorrhage
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Collection of blood between the inner surface of the skull and outer layer of dura mater.
Seen in people who have sustained head trauma (associated with skull fracture)
Source of Bleeding: Middle Meningeal Artery (most common) at the Temperoparietal Locus
CT Scan Appearance: Biconvex in ShapeSymptoms: Lucid interval followed by
unconsciousness, Headache due to stripping of the dura from the skull, increase intracranial pressure, dilated pupil on side on injury, weakness of the extremities on the opposite side of lesion
Epidural Hemorrhage
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Epidural Hemorrhage
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Blood accumulating between the dura and arachnoid mater of the meninges around the brain
Young adults - Motor vehicle accidents, Elderly – Falls, Infants – Non-accidental injuries
Source of Bleeding: Stretching and tearing of Bridging Cortical Veins
CT Scan Appearance: Crescent shaped hematoma
Symptoms: Depressed Conscious State, Pupillary Abnormalities, Chronic cases in Elderly presents with Pseudo-Dementia
Subdural Hemorrhage
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Subdural Hemorrhage
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Bleeding in the subarachnoid space (between the arachnoid membrane and pia mater)
More common in men less than 60 years of ageMajor cause is rupture of a Cerebral Aneurysm,
other causes include trauma (with cerebral contusion), can be spontaneous (berry aneurysm), Dural Arteriovenous Fistula, Cocaine use etc.
Symptoms: “Thunderclap” Headache, confusion and lowered level of consciousness, seizures, Terson Syndrome, Signs of Meningism (photophobia, nausea, vomiting and neck stiffness)
Subarachnoid Hemorrhage
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Subarachnoid Hemorrhage
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CT Scan
CT Angiography
CT Venogram
MRI
DSA (Digital Subtraction Catheter) Angiography
Diagnosis
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Treatment of Underlying Cause of Hemorrhage (eg. Aneurysm, AVM)
Treatment of Obstructive Hydrocephalus
Evacuation of the clot (via burr-hole or craniotomy)
Triple H therapy (Hemodilution, Hypertension, Hypervolemia)
ICP monitoring
Calcium Channel Blocker (nimodipine)
Treatment
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A 72-year-old woman trips on a toy truck left at the top of a flight of stairs by a grandchild and falls down the stairs. She does not lose consciousness. About 36 hours later, she develops a headache and confusion and is taken to the emergency department. On physical examination, she is conscious and has a scalp contusion on the occiput. What is the most likely location of an intracranial hemorrhage in this patient?
A. PontineB. Basal GangliaC. Epidural D. Subdural
Case Study
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http://www.nationaltraumainstitute.org/home/hemorrhage.html
http://www.webmd.com/brain/brain-hemorrhage-bleeding-causes-symptoms-treatments
http://radiopaedia.org/articles/intracranial_haemorrhage
http://emedicine.medscape.com/article/1137207-overview
http://interestingmedfacts.blogspot.com/2013/01/hemorrhage.html
References