Clinical Proof for Ashwagandha

In one clinical study involving mice subjects, 1.4mg/kg of ashwagandha was administered daily for 20 days consecutively. T4 levels were shown to increase significantly, but there were no changes noted in T3 levels. In a different study, both T3 and T4 levels increased using the same protocol variables. The only difference between the two studies was that only male mice were used as subjects in the later study.

A 12% increase in hepatic (liver) antioxidant enzymes was noted as well as 34% slowing of lipid peroxidation. Further, T4 levels increased by roughly 60%, and no significant changes in T3 were noted. When ashwagandha for thyroid support was combined with Bauhinia bark and guggulsterone gum, T3 levels also increased.

Conclusions

Supplementation with ashwagandha for thyroid functioning improvements continues to be validated in animal trials. Human trials have been warranted, but may take years to complete. T4 and T3 levels have been shown to increase via ashwagandha usage, but there seems to be a gender difference that allows men to generate T3 as well as T4 under the same protocol that women only generate T4 with.

Thousands of years of traditional usage, as well as clinical research shows the general safety of Withania somnifera. It is well tolerated in healthy individuals, however side effects and interactions with drugs and/or other herbals are possible for certain people.

As it is versatile substance which affects various body systems at the same time, ashwagandha dosage for thyroid improvements should be approached cautiously and slowly. Consult with a physician and follow all manufacturer’s’ instructions when supplementing at home.

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