clinical data of benchtop incubatorsming-mei.com.tw/files/twlyav9gbhllcl8ymdezx3... ·...

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KEY FEATURES: Consist of six (6) isolated chambers. Each chamber can contain 4- 8 standard culture dishes. High- performance temperature sensors. Advanced temperature control by providing direct heat. With heated lid, oil overlay will not be required. 12 x PID regulation system, the most advanced in the world With gas mixer. Conveniently use pure gas (CO 2 and N 2 ) inputs to control CO 2 levels and even obtain suppresses O 2 levels. No need for pre- mixed gas which can also reduced operating costs. The air quality in the chambers is continuously cleaned and sterilized via HEPA/ VOC filters and optional UV. Full parameter display at a distance. Multi-room CO 2 incubator for IVF Miri® The Miri is a certified EU Class IIa Medical Device and it is also the only incubator that has been certified to the 3rd edition of the IEC/EN 60601 standard. It is thus no wonder that the remarkable characteristics of the Miri make it an entirely exceptional incubator for in vitro fertilization applications. With Esco Medical and the Miri, life has just begun. Esco Micro Pte. Ltd. 21 Changi South Street 1 • Singapore 486 777 Tel +65 6542 0833 • Fax +65 6542 6920 [email protected] www.escoglobal.com Esco Global Offices: Manama, Bahrain | Beijing, China | Chengdu, China Guangzhou, China | Shanghai, China | Bangalore, India | Delhi,India Mumbai, India | Banten, Indonesia Osaka, Japan | Kuala Lumpur, Malaysia Melaka, Malaysia | Manila, Philippines | Singapore Midrand, South Africa Seoul, South Korea | Hatboro, PA, USA | Salisbury, UK Hanoi, Vietnam EU MDD Class IIa Medical Device tested and certified IEC/EN60601-1 3rd Edition MDD Class IIa Medical Devices Miri® Installations in Europe Denmark Sweden Spain Russia Italy VIP treatment for cultured embryos in IVF

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Page 1: CliniCAl DAtA Of BEnCHtOP inCUBAtOrsming-mei.com.tw/files/TWlyaV9GbHllcl8yMDEzX3... · 2013-07-16 · Maimonides Medical Center, Brooklyn, new York 11228. While the influence of patient

KEY FEATURES:

Consist of six (6) isolated chambers.

Each chamber can contain 4- 8 standard culture dishes.

High- performance temperature sensors.

Advanced temperature control by providing direct heat.

With heated lid, oil overlay will not be required.

12 x PID regulation system, the most advanced in the world

With gas mixer. Conveniently use pure gas (CO2 and N2)

inputs to control CO2 levels and even obtain suppresses O2 levels.

No need for pre- mixed gas which can also reduced operating costs.

The air quality in the chambers is continuously cleaned and

sterilized via HEPA/ VOC filters and optional UV.

Full parameter display at a distance.

Multi-room CO2 incubator for IVFMiri®

The Miri is a certified EU Class IIa Medical Device and it is also the only incubator that has been certified to the 3rd edition of the IEC/EN 60601 standard. It is thus no wonder that the remarkable characteristics of the Miri make it an entirely exceptional incubator for in vitro fertilization applications. With Esco Medical and the Miri, life has just begun.

Esco Micro Pte. Ltd. 21 Changi South Street 1 • Singapore 486 777Tel +65 6542 0833 • Fax +65 6542 6920 [email protected] • www.escoglobal.com

Esco Global Offices: Manama, Bahrain | Beijing, China | Chengdu, China Guangzhou, China | Shanghai, China | Bangalore, India | Delhi,India Mumbai, India | Banten, Indonesia Osaka, Japan | Kuala Lumpur, Malaysia Melaka, Malaysia | Manila, Philippines | Singapore Midrand, South Africa Seoul, South Korea | Hatboro, PA, USA | Salisbury, UK Hanoi, Vietnam

EU MDD Class IIa

M e d i c a l D e v i c e

tested and certified

IEC/EN60601-13rd Edition

MDD Class IIa

Medical Devices

Miri® Installations in Europe

Denmark Sweden

Spain Russia

Italy

VIP treatment for cultured embryos in IVF

Page 2: CliniCAl DAtA Of BEnCHtOP inCUBAtOrsming-mei.com.tw/files/TWlyaV9GbHllcl8yMDEzX3... · 2013-07-16 · Maimonides Medical Center, Brooklyn, new York 11228. While the influence of patient

Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and pharmaceutical equipment solutions. Products sold in more than 100 countries include biological safety cabinets, fume hoods, ductless fume hoods, laminar flow clean benches, animal containment workstations, cytotoxic cabinets, hospital pharmacy isolators, PCR cabinets, thermal cyclers and instrumentation.

With the most extensive product line in the industry, Esco has passed more tests, in more languages, for more certifications, throughout more countries than any biological safety cabinet manufacturer worldwide. Esco remains dedicated to delivering innovative solutions for the clinical, life science, research and industrial laboratory community.

PT Esco Bintan IndonesiaCert. No: 651333/E

Esco Micro Pte Ltd Cert. No: 651076LIVE SUPPORT

escoglobal.com

Conventional Incubators VS Miri®

Conventional Incubators MIRI®

Impact to other

samples when

incubator is accessed

YES NO

Ability to regulate

temperature of sample while lid is

opened

NO YES

Temp recovery 6 Min 1 Min

Gas recovery 4 Min 3 Min

Gas consumption HIGHER LOWER

CliniCAl DAtA Of BEnCHtOP inCUBAtOrs

results showed an increase in fertilisation rates in 16 out of the 18 embryo strains tested. Many of the embryos tested in the benchtop incubator had an increased fertilisation rate of well over 3 times that of the standard incubator. “Another week of IVF and results look fantastic, really a sea change over what we have grown used to and in parallel testing, always significant with fertilisation rates as high as 100%.” --rosewell, i. (2011). Benchtop incubator Gives Cancer research a Boost. Cancer research UK.

With the top-load mini-incubator, the time necessary to for the temperature to recover after the 5-s opening of the incubator door was approximately 5 min for both inside the chamber and in the dish (36.9–37.0ºC). the microenvironment maintenance ability of incubators appears to significantly influence the formation of good embryos. -- fujiwara, M., takahashi, K., izuno, M., Duan, Y., Kazono, M., Kimura, f.,& noda, Y. (2006). Effect of micro-environment maintenance on embryo culture after in-vitro fertilization: comparison of top-load mini incubator and conventional front-load incubator. Assist reprod Genet 24:5–9. DOi 10.1007/s10815-006-9088-3

Given the increase in fertilization rates, embryo quality, and pregnancy rates, as well as, the space savings from the smaller footprint of the incubator, we believe that a culture system incorporating triple gas (low O2), a mini bench-top incubator, along with compatible culture media, is the way of the future in human IVF laboratories.-- lee, M., Grazi, r.,& seifer, D. incorporation of the Benchtop incubator and Media system into the iVf lab: the future of iVf. Genesis fertility and reproductive Medicine, Department of Obstetrics and Gynecology, Division of reproductive Endocrinology, Maimonides Medical Center, Brooklyn, new York 11228.

While the influence of patient age upon gamete quality is undeniable, this study illustrated that the laboratory’s culture system also had a significant effect on iVf fertilization rate and subsequent embryo development for older patients. -- Mortimer, s., fluker, M.,& Yuzpe, A. (2003). Effect of culture system upon fertilization rate and embryo development for patients 40 years and older. Genesis fertility Center, Vancouver, BC, Canada.

MRA-1014 - Stacking frame for two unitsMRI-6A10 - Esco Miri Multi-Room Incubator