Clinical aspects of managing the cardiovascular risk in diabetes

Dr SH Song MD FRCP

Consultant DiabetologistNorthern General HospitalSheffield

Increased CHD in type 1 diabetesLaing at al Diabetologia 2003; 46: 760-5

STENO-2Evidence - Intensive multifactorial intervention are effective in reducing CVD events in type 2 DM Behaviour modification (weight, diet, smoking cessation)

Pharmacological intervention aimed at diabetes, hypertension, lipids along with aspirin and ACE-I50% reduction in CVD events, nephropathy, retinopathy and neuropathy

Risk reduction 20% higher than single-factor intervention studies (glycaemia, BP, lipid lowering)

Important to target all risk factors

JBS2 guidelines 2005Treatment targets for patients with diabetes:HbA1c 6.5%BP

Glycaemic control

Glycaemic control and CVD events

Effect of reducing HbA1c: UKPDS1% reduction in HbA1c significantly reduced the risk of diabetes-related complicationsStratton et al. BMJ 2000; 321: 405412Microvascular complicationsAny diabetes-related endpointMyocardial infarctionAmputation or death from PVDStroke* -37%* -21%* -14%* -43%** -12%UKPDS, United Kingdom Prospective Diabetes StudyPVD, peripheral vascular diseaseMedian follow up = 10 years, n = 3642 for relative risk analysis Primary endpoint; *p

UKPDS found that metformin reduces risk of macrovascular complicationsdeath051015202530354045P=0.0023P=0.02P=0.010P=0.017P=0.011Diabetes50% risk reductionrelated outcome

AnyMacrovasculardiabetesMyocardialinfarctionrelatedAll causemortalityUKPDS 34. Lancet 1998;352:854865

Relative RR 16%, p=0.027End-point: all-cause mortality, non-fatal MI, stroke?Glitazone reduce CVD events

Post-hoc analysis

Effects of Pioglitazone in patients with or without a history of stroke an analysis of PROactive

Robert G. Wilcox; Marie-Germaine Bousser; John Betteridge; Guntram Schernthaner; Valdis Pirags; Stuart Kupfer ; John Dormandy

Time to Fatal or Non-Fatal Stroke in Patients with Previous Stroke

N at Risk:

Time from Randomisation (months)

984

952

926

903

877

849

132

Kaplan-Meier event rate

0.04

0.06

0.08

0.10

0.00

0.12

0

6

12

18

24

30

36

pioglitazone(27 / 486)

placebo(51 / 498)

0.02

0.008

0.34, 0.85

0.53

pioglitazone vs placebo

p value

95% CI

HR

Time to Fatal or Non-Fatal Stroke in Patients with Previous Stroke versus no Previous Stroke

Previous Stroke*

No Previous Stroke

*HR 0.53 (O.34-0.85) p0.008

Summary:

In T2DM with CVD, pioglitazone reduced risk of recurrentfatal/nonfatal MI by 28% and ACS by 37%

In T2DM with previous stroke, pioglitazone reduced risk ofrecurrent fatal/nonfatal stroke by 47%

In T2DM without previous stroke, pioglitazone has no effecton reducing the risk of first stroke

Blood pressure

Kannel WB, et al. Am Heart J. 1991;121:1268-1273.Blood Pressure and CVD: Framingham Heart StudyNo Glucose IntoleranceGlucose IntoleranceAge-adjusted CV Event Rate/1,000Systolic BP (mmHg)105135165195Systolic BP (mmHg)105135165195Age-adjusted CV Event Rate/1,00024503877591199017415312348367456113No Glucose IntoleranceGlucose IntoleranceMENWOMEN

Relative Risk of Stroke and of CHD Increases with Increasing DBPMacMahon S et al. Lancet 1990;335:765-774Stroke and usual DBPCoronary Hearth Disease and usual DBP(in 5 categories defined by baseline DBP)7 prospective observational studies: 843 events4.002.001.000.50768491Approximate mean usual DBP98105mm Hg12345768491Approximate mean usual DBP98105mm Hg12345BaselineDBP categoryBaselineDBP category4.002.001.000.500.250.25(in 5 categories defined by baseline DBP)9 prospective observational studies: 4856 eventsRelative Risk of StrokeRelative Risk

UK Prospective Diabetes Study Group. BMJ 1998; 317: 703713.Preventing cardiovascular complications UKPDS: benefits of reducing blood pressure-47-44-56-34-37-32-24-75-50-250% Risk reduction associated with tighter blood pressure control*p = 0.019p = 0.0046p = 0.0092p = 0.0038p = 0.0036p = 0.013 p = 0.0043Any diabetes-related endpointDiabetes-related and all-cause mortalityRetinopathy progressionMicro -vascular diseaseVision deteriorationStrokeHeart failure*Tight control vs less tight control = 144/82 mmHg vs 154/87 mmHg

Major Outcomes of the Hypertension Optimal Treatment (HOT) Trial: Diabetes SubgroupHansson L, et al. Lancet. 1998;351: 1755-1762.Major CV EventsMIEvents/1000 Pt-YearsCV Mortality90 mmHg (N=501)85 mmHg (N=501)80 mmHg (N=499)Diastolic Targetp

BP Treatment Threshold

JNC 7ESH-ESCWHO-ISHBHS IV 2004140/90140/90All risk strata140/90160/100-Inc? low risk

130/85 v high and high riskConsider resources140/90 10 year CV risk 20%

BP Targets

JNC7ESH-ESCWHO-ISHBHS IV 2004

Updated UK NICE Guidelines for the Treatment of Newly Diagnosed Hypertensionhttp://www.nice.org.uk/download.aspx?o=CG034fullguideline. Accessed June 2006 *If ACE inhibitor (ACEI) not toleratedACEI (or ARB*) + CCB orACEI (or ARB*) + thiazide diuretic

Principles behind latest BP guideline in the UK

Monotherapy inadequate

Underscores the need for at least 2 drugs

Provides rational for drug selection based on ethnicity and age

Not restrictive or prescriptive & offers therapeutic choice

Lipid

Spectrum of CHD Risk to guide lipid-lowering strategyExpert Panel. JAMA 2001;285:2486-2497.MetabolicSyndromeLDL-C HDL-CTG +Glucose intoleranceAbdominal obesity BPShould we treat low HDL?Achieving low LDL/total cholesterol targetevidencehow to achieve it?Lipid-lowering guidelines (JBS-2, NICE type 1 DM) and young diabetics ?role of metabolic syndrome

Diabetic dyslipidaemialow HDL (

Statin potent agent in lowering total/LDL cholesterol

consistently demonstrated importance of lowering LDL/total cholesterol to reduce CVD events

agent of choice for lipid-lowering Rx I guidelines

important component of multi-factorial diabetes management

easier component to achieve targettot chol 70-75% BP 50%, HbA1c 15% (STENO-2)

recent trials showed lower the better (HPS, TNT, PROVE-IT)

Reduction in 1 mmol/l LDL leads to 20-25% reduction in CVD events (major coronary events, coronary revascularisation and ischaemic stroke)

Target total/LDL cholesterol - the lower the better Statin meta-analysisLancet 2005

Lower cholesterol target strategies to achieve it (1)Use more potent statin

Rule of 6

Majority of LDL-C Lowering Occurs at the Lowest Statin Dose

Atorvastatin 10/20/40/80 mg 211 mg/dl*

Simvastatin 10/20/40 mg 219 mg/dl*

Mean % Change from Baseline

Adapted from Jones P et al. Am J Cardiol 1998;81:582-587.

*Mean baseline LDL-C. At the time of this study, the maximum dose for simvastatin was 40 mg.

Daily Dose

16% with 3 Titrations

13%

38%

46%

51%

54%

28%

35%

41%

Most guidelines simvastatin (1st) and atorvastatin (2nd)Statin choice if these statins fail to achieve cholesterol target

MERCURY II

Initital Rx:Switched to:% reduction in LDLAtorvastatin 10Rosuvastatin 1017

Atorvastatin 20Rosuvastatin 2016

Simvastatin 20Rosuvastatin 1018

Simvastatin 40Rosuvastatin 2027

Ballantyne CM et al. Am Heart J 2006: 151; 975Lower cholesterol target strategies to achieve it (2)Switching to more potent statin

Lower cholesterol target strategies to achieve it (3)

Adding fibrate, nicotinic acid and ezetimibe to statin

LDLTGHDL

Statin + fibrate-28%-41%+22%

Statin + niaspan (1g)-8%-24%+24

Statin + niaspan (2g)-23%-30%+27%

Statin + ezetimibe-20%-11%+1.7%Fibrate and nicotinic acid LDL, TG, HDLEzetimibe - LDL

No role for CVD risk calculation tableTo guide initiation of lipid-lowering treatment in primary preventionCalculates absolute risk of developing CHD (over 10 yrs)introduced when statin cost was expensive (predominantly financial reason)prior to statin trials in diabetes (HPS, CARDS)not evidence-based

Purpose:to target high risk individuals to maximise cost-effectivenessto reduce unnecessary treatment in some individualsJBS (1998) and NICE (2002) recommends risk tablesstatin Rx when >15% (NICE) or >30% (JBS)

Available risk calculators:Framingham & UKPDS risk engine

Framingham equation under-estimate CHD risk in diabetes up to 50%

PredictedObserved

UKPDSCHD event (%/yr)1.62.7(Diabetes)

WOSCOPSCHD event (%/yr)1.91.8(Non-diabetes)

(Yeo et al Diabet Med 2001; 18: 341-44)

CardiffCHD eventMale8.319(Diabetes)(% / 4 yrs)Female7.517

Stevens et al Diabet Med 2005; 22: 228

UKPDS risk engine is not a better alternative

Comparison between UKPDS risk engine and Framingham equationSH Song et al Diabetic Med 2004; 21: 238-45Mean CHD risk (over 10 yrs) in type 2 diabetes

malefemaleJBS1917.3UKPDS24.916.5

Conclusion:

Overall, UKPDS risk engine estimated higherCHD risk score. At high risk (>30%), UKPDSrisk engine consistently estimated higher riskscore than Framingham equation. At lower risklevels (~15%) where clinical decision to startstatin occurs (as per NICE), UKPDS risk engineand Framingham equation equivalent. 15% thresholdUKPDS risk engine betterFramingham calculator better

Why under-estimate risk in diabetes?

Model based on largely non-DM population (Framingham calculator)

Traditional risk factors do not account for excess CHD death in diabetes. Other important factors not included in risk calculation. (ie small dense LDL, microalbuminuria, hypercoagulable state, impaired fibrinolysis, endothelial dysfunction, inflammatory states, insulin resistance etc)

Other limitations:

No risk calculation method for type 1 diabetes.

Young type 2 diabetes increasing and risk cant be calculated by current methods.

Forms the basis for degree ofaggressiveness with lipid Rx

Young T2DM patients

Facts:

high CVD risk (especially with CVD risk factors) no trial data in this age group (compared to >40yrs HPS/CARDS) increasing number of young T2DM patients

SH Song, CA Hardisty. Practical Diabetes International 2007;24: 20-24 Sheffield experience

Young type 2 diabetes patients:Similar CVD risk profile as older type 2 diabetes patients

High prevalence of obesity, hypertensionand dyslipidaemia

Less likely to be treated with statin andanti-hypertensive agents

Sheffield experience

Tendency to multiple CVD risk factor clustering in young type 2 diabetes patients ofsimilar proportion to older T2DMSH Song, CA Hardisty. Practical Diabetes International 2007;24: 20-24

High prevalence of metabolic syndrome in T2DM regardless of age ~70% 40 yrs 70IDF ATPAverage WC ~113 cm or 44 inches(male and female) 70SH Song. Presented at EASD Copenhagen 2006 Sheffield experience (2)

Chart4

68.875

92.992.9

9798.5

93.592.2

96.993.8

Age group

MetS prevalence (%)

Sheet1

68.892.99793.596.9

7592.998.592.293.8

Sheet1

Age group

MetS prevalence (%)

Sheet2

Sheet3

Chart1

114.2110.2

117.3113.9

118.1115.9

111.4114.4

110.4108.7

female

male

age group

waist circumference (cm)

Total

NameagesexDM typeDM durationage onsetweightheightBMIWCHbA1ctotal CholHDLTrigcreatsys BPdias BPBP RxStatinfibrateHTNIHDCVAPVDretinopaneuropaeMDRDethnic

Vickers Mavis60f285290.91.6533.38842975211196.24.11.162.211814183yynynnynn

Simpson Donald76m2175731.5231.5962603878986.15.41.361.311213460yynynnnny

Hayes Philip62m28541051.7534.28571428571177.66.10.984.110415460ynnyynnnn

Wigfield Alan42m26361251.7839.45208938271237.63.91.37215571yynynnnnn

Furness barbara76f2245263.71.6523.39761248858810.13.61.510.89818373yynynnnyn

Rafiq maqsood52f264683.61.5136.665058550112111.23.70.843.512016674yynyynnnypakistani

Rowland doris63f2954110.31.738.16608996541236.13.41.061.49614450yynynnnny

Wood lily74f2393567.51.5129.60396473841226.64.30.971.512212167ynnynnnny

Simpson colin81m2117082.11.6430.52498512791105.93.91.022.29917070ynnynnyyy

Smithson harry72m27287.61.7229.61060032451205.84.71.416116070ynnynnnyn

Yafai m73m2274663.91.5128.0250866191057.241.35111712772yynyynnynarab

Hind george58m21147105.81.6240.3139765281259.52.80.960.68215272yynyynnyy

Reed derek73m2195488.61.7329.603394700810810.32.80.831.316514873yynyyyyyy

Baker betty75f257062.11.5127.2356475593916.84.21.242.78312262yynynnnny

Allsebrook godfrey68m2194995.51.6136.84271440151295.22.92.190810060yynynynyy

Fazal Kalsoum72m2195394.31.6235.932022557512893.10.734.19111460yynynynyypakistani

Staniland stephen50m2173392.81.6932.491859528711410.540.743.88114380yynynnnnn

Stott patricia56f2124484.81.5734.40301837811765.51.312.59414881ynyynnnyy

Lang christine50f22481281.7243.26663061111349.73.91.491.66613070yynynnnnn

Hopkins winifred63f2174694.71.6236.08443834781299.43.90.891.77713767yynynnnyy

Brammer roger56m21145761.7524.81632653061016.33.90.774.19713866nynnynynn

Crookes elaine62f21052108.41.7336.21905175581247.52.70.751.26914464yynynnnny

Ward david57m22532105.71.6638.35825228631307.85.11.21.816016590yynyynnny

Bailey dorothy55f228271169.55.82.171.512713262ynnynnnyyafro carri

hatch lilian44f244150.31.5661.76035502961166.53.20.980.76511662nnnnnnnnn

Garner doreen56f255178.21.4835.70124178231187.75.20.93.75913874nynnnnnnnproteinuria

khan dawood45m244184.21.7427.81080724011028.85.31.223.27810965yynyynnnnpakistaniproteinuria

singh gucharan59m2164373.21.6626.5640876761067.83.51.071.710312268yynyynnnn

trainor steven40m2535114.81.7637.06095041321299.23.91.211.86511566yynynnnnn

Wallis roger62m21547127.41.8537.22425127831456.64.40.972.49415769yynyynyny

seymour mary61f2164575.61.4834.51424397371047.45.50.913.712313371yynynnnyy

king pauline73f2469107.11.6539.33884297521229.45.40.954.68417479yyyynnnnn

patterson kenneth78m278911.828.08641975311137.14.31.151.318817784ynnynnnyyproteinuria

marshall elsie72m2171115.61.645.156251305.94.51.441.98117074ynnynnnnn

shepard allan36m2432100.91.7134.50634383231155.95.21.225.88314888yynynnnyn

didsbury valerie60f295189.41.7529.19183673471129.551.112.810618375yynynynnn

cooling lesley58f25881.71.6231.13092516381107.64.90.922.36212861yynynnnyy

margerrison raymond71m2106191.71.7230.99648458631146.34.11.331.17516877ynnynnnnn

nortcliff william67m2364105.31.8530.76698319941357.45.11.061.97813386yynyyynny

ali maqsood61m2154686.51.7727.61020141081088.83.50.751.911014275yynyynynana

thornton peter51m274481.51.4936.71005810551217.14.51.650.810010365yynynnnnn

cooper diane66f2165090.41.5239.12742382271279.53.90.894.27815276yynyynnnn

priestley colin55m2183795.11.7730.35526189791136.73.40.971.58312871nynnynnnn

murdoch philip45m254082.31.7227.819091400810110.95.81.371.48615895ynnynnnnn

campbell asher70m276385.11.5535.42143600421106.74.21.451.79814378yynynynnn

stansall roy59m21445110.11.7535.95102040821318.25.61.52.19717070ynnynnnyn

watson ann66f2155193.21.6733.41819355312394.60.982.312812769ynnynnnyy

judge mary61f275460.81.3732.3938409079967.24.71.373.58311063nynnnnnnn

whittaker brian63m2125199.91.8828.26505205981258.53.70.981.86317494yynynynnn

wood freda68f2105869.41.5728.155300417998104.91.015.410011060yynynnnny

ellis malcolm61m2952152.31.847.00617283951506.43.50.95311314580yynyynnyyproteinuria

begum janat64f2361103.61.5244.84072022161327.93.12.225916486yynyynnyyproteinuriapakistani

grey burnice71m2304198.91.5541.16545265351196.34.60.961.310114786yynynnnnn

smith lesley77m2146361.41.6722.01584854249784.40.912.29414060yynyynyyn

ward james21m2120130.21.8438.45699432891367.95.61.640.77312456nnnnnnnnn

dawson alan73m21063110.31.7436.43149689521297.24.30.881.510113878ynnynnnnnproteinuria

ruban tareq51m2123988.31.7827.86895593991069.43.30.9329513475nynnnnnnn

rajah saleh75m286766.81.6325.1420828785996.540.850.613015870ynnyynnnn

majid nazir71m2145762.11.4828.35098612131068.63.41.181.66713570ynnyynnyy

holroyd barbara73f2205381.91.5235.44840720221455.93.61.21.313215570yynynnnyn

cox alan69m21851109.31.737.82006920421209.77.20.8517.113014080yyyyynnnn

everitt geoffrey59m2124784.61.6730.33454049981197.65.11.173.927713492yynyynnnn

bi akhtar49f2292048.81.5221.1218836565928.85.11.123.16113269nynnnnnyn

hussein saffder39m263372.71.7523.73877551029112.83.40.941.87711473nnnnnnnnn

rowbotham ronald74m2215365.71.7122.4684518313958.64.11.011.521112960ynnyynnyyproteinuria

bellis shelah54f219351061.641.4062512693.51.121.57510060yynynnnyn

pendall brian62m23329117.21.7936.57813426551228.13.41.350.89611573yynynnnyy

khan abbas36m253182.91.7327.69888736681035.651.191.78911270nnnnnnnnn

everitt joan67f2105797.81.6137.73002584781268.33.90.752.69612068yynyynnnn

butler james59m2104978.61.7326.26215376391056.17.72.630.913570ynnynnnnnproteinuria

crompton dawn44f2172795.41.5539.70863683661248.95.11.122.675160100nnnnnnnyn

burns joyce79f2166357.51.622.46093759010.25.41.431.810214570yynynnnyn

shakespeare christina57f2354103.61.640.4687513766.31.253.118310560ynnyyynnyproteinuria

ellis tony60m215981.91.7227.6838831801103105.916.28916395yynynynnn

khan lalmar59m295099.61.7333.2787597314124114.40.962.38313269yynyynnyy

patterson evie73f276688.31.5437.232248271212684.51.790.79515779yynynnnyy

ahmed razina59f2104961.51.5724.950302243510374.60.9246511763nynnynnny

din zakavath65m2135266.91.6424.87358715051046.54.71.320.78512857nynnnnnyy

rothwell joan65f2956123.81.648.3593751436.73.71.273.79613055yynyynnnn

chilton alan62m2134976.31.7225.79096809091076.841.010.96214080yynyynnyn

richards brenda75f27583.41043.51.292.313572yynyyyn

warren dorothy67f2364113.51.6243.24798049081166.62.71.071.26714268yynyynnnn

jan farooq71f2764741.5530.801248699312212.36.11.012.314070ynnyynn

frost julie47f2740116.11.6741.62931621791379.25.61.262.56312670nnnnnnnny

hussain luftun32f223056.51.5224.4546398892937.73.40.870.96711868nnnnnnnnn

benton margaret70f2155561.11.5326.101072237210393.71.121.415362yynynnn

naughton irene34f21024125.91.6247.97286998931278.85.30.992.77015490nnnynnnyn

ahmed fatima70f2155562.91.4928.3320571145986.63.81.1225118490yynynnnyn

beasley martin49m21633112.81.7935.20489372991256.23.31.181.411677yynynnn

webster evelyn83f297483.91.6132.36757841131105.83.51.040.917995yynyyny

stacey maureen67f276090.21.635.2343751208.54.81.178311570yynynnnyy

hurditch john63m2144995.41.8129.11999023231167.440.925.712817281ynnyynnnn

wilson carol61f285381.21.6828.76984126981096.95.30.991.95512060ynnyynnny

akhtar shaheen33f213279.81.6628.95921033531165.651.082.25911459nnnnnnnnn

williamson brenda64f285688.91.634.72656251207.23.90.82.98810075ynnyynnnn

dad jamilla60f2174358.51.6322.01814144310111.66.31.133.95510775nnnnnnnnn

khaliq abdul71m2195274.61.6627.07214399771099.951.17212112759nynnynnynproteinuria

white betty69f21257851.6331.992171327513073.71.072.110512045yynyyyyny

freebre lynne31f213084.51.6730.2986840691127.751.052.77012281nnnnnnnnn

moody adrian49m1292077.21.7525.2081632653887.94.61.82.48611864nnnnnnnyn

edis roy67m166183.81.7627.053202479310610.14.31.451.96411870nnnnnnnny

forrest david62m1154787.31.7229.5091941591028.43.920.810112768nynnnnnnn

carr francis73m1363784.41.729.20415224911036.24.41.50.49618277yynyynnnn

harrison geoffrey74m1551972.21.6925.2792269178888.231.430.715516365nynynnnyy

twyford andrew31m122990.81.8526.53031409791057.44.61.930.48912082yynynnnyy

hannah william57m1282988.51.7130.26572278651077.83.41.430.88512259yynynnnyy

bray robert47m146183.41.6929.20065824031109.57.71.940.713914770ynnynnnyy

aldridge paul60m1174380.21.7227.1092482423946.64.82.130.410912140nynnnnnyn

wilson stephen52m11537100.91.831.14197530861218.44.81.921.510013070nynnnnnnn

gibbings rose61f1372461.71.6223.5101356501836.24.51.680.58712053ynnynnnyy

armitage lorna57f1342366.91.6723.98795223928210.84.51.650.811016070yynynnnyn

akinti sophie35f192677.31.6628.0519669038948.73.60.991.66611473nnnnnnnnn

spence raymond58m1322676.51.6727.4301696009977.83.20.930.914213066yynynynyy

greene tina39f1152479.31.6329.8468139561998.84.81.940.68712964nnnnnnnnn

piper keith57m1441370.21.724.2906574394957.64.31.061.210311354nynnnnyyyproteinuria

hewitt doreen74f2116387.91.5735.66067588951245.23.10.951.77615768yynynnnnn

lancaster graham66m275974.71.5929.54788180851057.35.10.921.713311274ynyynynnn

saunders terence62m2204265.81.7820.7675798519410.151.1226513070nynnnnnny

fish anne47f224599.61.6536.584022038611310.14.11.142.38115577yynynnnnn

modest beverley58f215774.31.629.02343751025.53.80.971.76315070yynynnnnn

shaibi saleh59m2554821.6729.402273297710974.70.850.97316397yynyynnnn

bi taseem53f2114278.71.5731.92827295221117.83.71.052.76712654yynynnnnyproteimuria

ellis stephen50m2173392.91.7829.32079282921009.54.50.943.6841370yynyynnyn

stirling brian48m2246891.7628.73192148761016.74.70.921.67613787nnnnnnnnn

khan waqar51f264566.11.6324.87861793821008.25.20.9526113681ynnynnnnn

beardall hilda83f2107348.71.4323.81534549378311.24.10.822.815414252yynyynnnn

watson neil61m2115082.21.8224.81584349721014.63.91.061.36512685nynnnnnny

james stephen51m264564.21.6423.8697204045877.73.80.88111113870ynnynnnyn

needham brenda68f2563100.61.5939.7927297181237.74.91.021.47712080yynyynnyy

briggs rachel33f242975.31.6926.36462308741035.450.983.94913280nnnnnnnnn

bingham peter62m21745102.91.8231.06508875741196.14.61.081.57915080ynnynnnyy

ellis maureen66f275981.31.5732.9830824781085.84.41.081.86013066yynyynnnn

farrar sylvia73f2271109.31.6142.16658307941198.94.71.470.87915469nynnnnnnn

ratcliffe frederick56m2650111.61.834.444444444412310.55.31.481.786180100yynynnnnn

grey oliver75m1126381.11.7227.413466738810711.43.70.650.88815580ynnyynnnn

benham c57f23541281.7243.26663061111357.34.90.491.57116582yynynnnnn

burkinshaw p60m245694.81.6236.12254229541145.64.61.131.68316880yynyynnny

stuart p44m1143090.71.7828.62643605611046.24.61.371.18912978nnnnnnnnn

allen k66f2283881.21.6330.561933079911110.851.9118711365yynynnnyy

jones a66f216568.31.6824.1992630385937.35.70.972.77612769yynynnnny

harrison pauline67f2204768.21.626.640625997.43.91.122.314411753yynynnnyn

bough b72m21755106.11.8232.031155657511783.51.022.215014578yynynynyy

beal j66f2105678.31.5433.015685613110473.71.281.17511753nynnynnyn

kulkani m36f213596.71.6236.846517299212110.361.091.97115270nnnynnnnn

stafford g62f2144885.51.633.398437511213.45.11.551.99515075yynynnnnn

wildgoose e62f1243849.21.5719.9602417948758.24.92.230.87714570yynynnnyn

beanes j70f2125884.31.6232.12162780061097.13.10.93.38612678yynynnnnn

ludlam g56f265086.21.5436.3467701131195.44.11.241.95813070yynyynynn

platts i46m273994.61.7530.88979591841119.37.61.484.77812070nynnynnyn

barrett j68f2204879.61.6728.541718957311892.60.881.24612368yynynnyyy

akhtar shamim51f254672.91.5231.55297783931067.56.41.234.17511769nynnnnnnn

brown d61m2160104.51.7832.98194672391286.43.71.361.25915678yynynnnyy

thabet s71m2185366.71.6225.41533302859913.35.70.763.68616271yynynnnnn

wilks m27f21261301.650.7812512554.20.990.96912575nnnnnnnnn

begum kaniz61f2253684.21.6530.9274563821177.36.51.542.210113060nnnnnnnyy

hill m46f21135116.11.6443.16627007731108.53.70.873.27813878yynynnnny

khan h78m2116782.71.6729.65326831371117.55.21.132.913015168nynnnnnnn

kirk m57f11245115.31.6343.396439459512610.64.30.951.98716279yynynnnny

smythe a44m2539128.41.8537.51643535431288.34.30.835.87912070yynyynnnn

cutts m67f2105773.61.5829.48245473481017.34.30.922.46913366ynnynnnyy

dronfield j60f21842108.81.7336.352701393311711.46.21.042.68715881yynynnnyy

riley h57f21146881.5138.59479847381256.650.843.412316775yynynnnny

holmes b73m2116275.71.7225.5881557599978.241.442.18012969nynnnnnyy

mahmood u71f2155683.41.5733.8350440181136.84.61.212.28712480yynyynnnn

lack m61f135892.41.6733.13134210621017.84.92.21.363140100yynynnnny

khan a53m2183579.41.6529.16437098261037.73.50.68214513667nynnynnyy

naughton emily70f21159861.6531.58861340681129.44.10.842.79214567ynnynnnnn

dero f74f2175796.71.7232.68658734451099.74.11.78116716277yynyynnyy

akbar f71f23041511.5222.0740997239210.241.161.26512070nynnynnny

elliot e70f22050100.81.5243.62880886431258.55.71.39314015055yyyynynyn

bilton r59f2154474.51.5232.2454986151119.64.40.893.410013080yynyynynn

revitt w79f24751461.6752.35038904231407.84.50.912.219014070ynnynnnyy

tyrell d60m22581231.9532.34714003941199.53.60.851.912214675ynnynnnyy

wood k66m2125493.91.7530.66122448981088.44.50.763.59012972nnnnynnyy

marshall m59f27521091.6341.02525499641197.62.90.9827912288yynyynnnn

weldon s57f1156101.51.7234.30908599241139.44.51.970.67013966yynnnnnnn

fisher m54f2252175.71.6862.2519841271515.44.31.5618414773nnnnnnnnn

james v59f1322795.81.5142.015701065713784.62.410.67915070ynnynnnyn

gunnee a48m2246127.81.8139.00979823571267.53.60.771.896150100yynynnnnn

wrigley se49f2346128.91.6348.51518687191427.44.71.212.17613070ynnynnnnn

simpson p52m21141165.21.8846.74060660931777.15.31.151.89616796ynnynnnny

mpundu c41m223995.81.829.567901234610410.73.91.061.69313975nnnnnnnnn

terry f57m265195.91.829.59876543211108.24.70.833.88310258nynnynnnn

rooke tm47f224577.21.5731.31972899511009.54.41.291.37113369nnnnnnnnn

okane km57m2849100.91.7333.71312105321208.54.31.054.76414276yynyynnny

frost b68m2244493.51.7331.240602759911410.64.10.822.813722586yynyynnyy

aslam k73f2145962.51.6722.41026928181016.84.41.113.17013668yynyynnny

horne d64m22539801.727.68166089971049.23.81.1137118390ynnynnnyy

roberts s52m2448119.51.7539.02040816331267.34.11.143.19313872yynynnnny

roberts v63f2657100.41.6138.73307356971197.941.1638713465yynynnnnn

scarlett a59m2134690.71.731.3840830451066.940.770.611516386yynynnnnn

newton j52f2646112.51.7238.02731206061157.73.81.111.56214385yynynnnnn

ali a42m253756.71.5423.90791027158863.30.821.98310058nynnynnnn

burditt s49m21138133.71.7643.162448347113711.24.20.84.37717698yynynnnnnnephropathy

tagg j40f25351041.6836.84807256241177.83.91.03266yynyynnnn

oxlade n57f2174096.51.6535.44536271811218.24.31.063.910014060nynnnnnny

timpany s61f235856.71.622.1484375747.64.41.880.78211462nynnnnnnn

neil s65f21451101.41.5542.20603537981247.24.21.221.17515070yynynnnyy

summerfield m35m113490.11.7529.42040816331106.93.90.922.98112570nnnnnnnnn

pryor j73m266795.71.6634.729278561206.73.11.020.99212363yynyynnnn

begum z63f2144974.91.6228.53985672921176.33.81.170.77814377ynnynnnny

wright k36f1251183.41.6729.9042633296918.47.42.311.78313070nnnnnnnnnnephropathy

walton h77m2136470.21.6326.4217697316968.33.71.081.58314244yynynnnnn

buckle h78m2156376.41.6727.39431317011097.95.21.031.610513776ynnynnynn

rayner g53m2350961.7232.44997295841214.93.61.120.812514881yynynynnn

lally r60f295182.51.6231.43575674441049.13.31.530.57716382yynyyynyy

jeffcock js78f2146490.71.5239.25727146811107.93.50.961.99014070yynynnnnn

morgan p69f2125765.61.6723.5218186382947.46.62.1511.57311068ynnynnnnn

goodwin b74f11460621.5426.1426884804867.24.61.6417811877nnnnnnnnn

willyeo p57f2174088.81.6134.25793757961118.34.31.611.112113961nynnyyyyy

bethell a51m274496.61.7133.035805889112114.51.052.210413288yynynnnnn

webster h20m118272.71.8621.01399005678011.43.91.550.57011257nnnnnnnnn

ellis r58m2184081.91.631.99218751099.15.61.232.213016686yynyynnyn

singh a57m2134488.31.6930.91628444381147.55.60.956.312812469nynnynnyn

lee g58m210481001.7333.41240936881267.94.21.152.87315472nynynnnnn

taylor s52f2232946.61.3425.9523279127729.24.92.70.810614855yynynnnnn

gauntley b70m21852100.11.7632.31534090911148.23.91.212.18915971yynynnnyn

hall j67f2105778.21.5831.325108155711513.14.30.972.77917490yynyyynnn

edge l53m2548160.51.7850.65648276731517.35.21.042.97712657nnnnnnnnn

chilvers d19m111865.61.7621.1776859504845.83.51.431.38010060nnnnnnnnn

bramley d69m22049102.51.735.46712802771187.931.090.918114963yynyynyyn

wigley g64m2361107.91.8132.93550257931067.63.60.861.611510874yynyynnny

thackeray t69f276262.61.5227.0948753463868.53.60.981.410213869yynynnnnn

williamson r80m277390.61.6931.721578376111410.84.61.231.717613768ynnynnnyn

khan rn43f283573.31.5331.312742962110410.14.80.814.46414289ynnynnnny

stansall j53f284575.11.5730.46776745511085.94.30.793.67212080yynynnnny

moody j70m2195178.11.7226.39940508381009.92.91.172.38214060yynynnyyn

kennedy m61f225959.11.5624.2850098619928.65.81.052.46217285nynynnnnn

bi z49f249851.5933.622087733911510.24.81.163.15516865nynynnnnn

evans d53m225180.81.6131.1716368967988.43.91.011.68713777yynynnnnn

bickerstaff n39m143570.71.7722.5669507485838.74.51.880.610112866nnnnnnnnn

summers j47f2146117.71.7438.8756771041187.45.21.1517513360nnnnnnnnn

samwell i63f2125185.61.4441.280864197511010.14.21.2529211577nynnnnynn

stones m75f2185766.91.4930.13377775781077.35.11.025.712618791yynynynyy

adnett-revill f73m2106379.31.7625.6004648761009.22.70.941.111611071nynnynnnn

hussain b56m2134379.21.727.40484429071126.33.50.991.48111667yynyynnny

sharpe r51m274488.71.8326.48630893731046.23.91.421.316113370yynynnnnynephropathy

green e59m235684.41.6630.62853824941116.33.91.311.616513070yynyynnny

fatima p56f274996.81.637.81251279.84.70.8416415670yynynnnyy

hall ap64m22143106.71.832.93209876541289.74.40.821.811212062nnynnnnny

mcallen k57m2453102.61.831.66666666671147.43.61.042.39512276nynnnnnyn

hague d75f21263103.41.640.39062513513.38.60.9710.99916380yynyyyynn

lees g71f2145798.61.5740.00162278391168.43.50.73414113359yynyynnnn

buckley m38m2137154.11.7351.48852283741537.14.41.091.611812276nynnnnnnn

khan h58f2154392.91.7331.04012830371218.74.50.961.96112076yynynnnny

murcott b66f216556.41.5423.7814133918896.33.71.131.28612064nynnnnnnn

clancy m74f256980.41.5433.90116377131068.43.71.321.27214687nynnnynyy

pymm pa62m245879.71.727.57785467131037.74.41.09211217391yynynnnyymicroalbuminuria

ayres d71m2215070.91.6526.04224058771048.12.20.661.47414874nynynnnnn

kent p59f212471181.6742.31058840413011.96.81.322.86416479yynyyynny

parkin sj58m21642116.71.7737.249832423613512.66.50.975.98615481yynynnnyy

carr s65f2105590.81.4443.78858024691249.14.21.12.410812555yynynnnny

hussain j49m2544821.6829.0532879819110.58.361.054.48712880yynyynnnn

kidus a31m2823731.6726.1751945211989.86.21.23.17013378nnnnnnnnn

roberts v44f2341120.11.5251.98234072021378.54.70.882.36016189yynynnnnn

hamilton ss34m213382.41.6829.19501133791037.95.40.920.98812272ynnynnnnn

malik r75f2156080.31.5632.99638395791138.93.71.21.66215973yynynynnn

ladva s72m2135958.21.6122.45283746779012.13.90.80.86616879nnnynnnnn

ullah a68m216779.51.6329.92208965341097.42.90.521.411815981yynyynnnyproteinuria

lamb d72m21656111.71.9429.67903071531207.62.40.830.513115475yynynnnyy

matthews i61f2655103.81.5244.927285318613273.51.011.415316981yynynnnynproteinuria

eckhardt a60m2114992.41.7530.17142857141076.95.11.32.19610060yynyyyynyproteinuria

roberts ga81m2166579.81.6728.6134318191068.25.71.721.28013070nnnnnnnyy

parkin g45m25401101.833.95061728411912.66.50.975.99115494yynynnnnn

male

NameagesexDM typeDM durationage osetweightheightBMIWCHbA1ctotal CholHDLTrigcreat(umol/l)sys BPdias BPBP RxStatinfibrateHTNIHDCVAPVDretinopaneuropaeMDRDethnic

Simpson Donald76m2175731.5231.5962603878986.15.41.361.311213460yynynnnny43.6122857143

Hayes Philip62m28541051.7534.28571428571177.66.10.984.110415460ynnyynnnn96.8625

Wigfield Alan42m26361251.7839.45208938271237.63.91.37215571yynynnnnn209.2708333333

Simpson colin81m2117082.11.6430.52498512791105.93.91.022.29917070ynnynnyyy60.1817878788

Smithson harry72m27287.61.7229.61060032451205.84.71.416116070ynnynnnyn45.5084720497

Yafai m73m2274663.91.5128.0250866191057.241.35111712772yynyynnyn45.0085384615arab

Hind george58m21147105.81.6240.3139765281259.52.80.960.68215272yynyynnyy130.134

Reed derek73m2195488.61.7329.603394700810810.32.80.831.316514873yynyyyyyy44.2516727273

Allsebrook godfrey68m2194995.51.6136.84271440151295.22.92.190810060yynynynyy9.3144052863

Fazal Kalsoum72m2195394.31.6235.932022557512893.10.734.19111460yynynynyy86.6730989011pakistani

Staniland stephen50m2173392.81.6932.491859528711410.540.743.88114380yynynnnnn126.8266666667

Brammer roger56m21145761.7524.81632653061016.33.90.774.19713866nynnynynn80.9517525773

Ward david57m22532105.71.6638.35825228631307.85.11.21.816016590yynyynnny67.44320625

khan dawood45m244184.21.7427.81080724011028.85.31.223.27810965yynyynnnn126.1380769231pakistaniproteinuria

singh gucharan59m2164373.21.6626.5640876761067.83.51.071.710312268yynyynnnn70.8050097087

trainor steven40m2535114.81.7637.06095041321299.23.91.211.86511566yynynnnnn217.2369230769

Wallis roger62m21547127.41.8537.22425127831456.64.40.972.49415769yynyynyny130.0293191489

patterson kenneth78m278911.828.08641975311137.14.31.151.318817784ynnynnnyy36.9130851064proteinuria

marshall elsie72m2171115.61.645.156251305.94.51.441.98117074ynnynnnnn119.3677037037

shepard allan36m2432100.91.7134.50634383231155.95.21.225.88314888yynynnnyn155.5075662651

margerrison raymond71m2106191.71.7230.99648458631146.34.11.331.17516877ynnynnnnn103.76772

nortcliff william67m2364105.31.8530.76698319941357.45.11.061.97813386yynyyynny121.2165

ali maqsood61m2154686.51.7727.61020141081088.83.50.751.911014275yynyynynana76.4109545455

thornton peter51m274481.51.4936.71005810551217.14.51.650.810010365yynynnnnn89.21805

priestley colin55m2183795.11.7730.35526189791136.73.40.971.58312871nynnynnnn119.791626506

murdoch philip45m254082.31.7227.819091400810110.95.81.371.48615895ynnynnnnn111.8227325581

campbell asher70m276385.11.5535.42143600421106.74.21.451.79814378yynynynnn74.7664285714

stansall roy59m21445110.11.7535.95102040821318.25.61.52.19717070ynnynnnyn113.085185567

whittaker brian63m2125199.91.8828.26505205981258.53.70.981.86317494yynynynnn150.183

ellis malcolm61m2952152.31.847.00617283951506.43.50.95311314580yynyynnyy130.9645221239proteinuria

grey burnice71m2304198.91.5541.16545265351196.34.60.961.310114786yynynnnnn83.1053762376

smith lesley77m2146361.41.6722.01584854249784.40.912.29414060yynyynyyn50.6158085106

ward james21m2120130.21.8438.45699432891367.95.61.640.77312456nnnnnnnnn261.0599178082

dawson alan73m21063110.31.7436.43149689521297.24.30.881.510113878ynnynnnnn89.9982475248proteinuria

ruban tareq51m2123988.31.7827.86895593991069.43.30.9329513475nynnnnnnn101.7494842105

rajah saleh75m286766.81.6325.1420828785996.540.850.613015870ynnyynnnn41.082

majid nazir71m2145762.11.4828.35098612131068.63.41.181.66713570ynnyynnyy78.6630895522

cox alan69m21851109.31.737.82006920421209.77.20.8517.113014080yyyyynnnn73.4243769231

everitt geoffrey59m2124784.61.6730.33454049981197.65.11.173.927713492yynyynnnn30.4285126354

hussein saffder39m263372.71.7523.73877551029112.83.40.941.87711473nnnnnnnnn117.2924805195

rowbotham ronald74m2215365.71.7122.4684518313958.64.11.011.521112960ynnyynnyy25.2773744076proteinuria

pendall brian62m23329117.21.7936.57813426551228.13.41.350.89611573yynynnnyy117.12675

khan abbas36m253182.91.7327.69888736681035.651.191.78911270nnnnnnnnn119.1524494382

butler james59m2104978.61.7326.26215376391056.17.72.630.913570ynnynnnnn0proteinuria

ellis tony60m215981.91.7227.6838831801103105.916.28916395yynynynnn90.5501123596

khan lalmar59m295099.61.7333.2787597314124114.40.962.38313269yynyynnyy119.556

din zakavath65m2135266.91.6424.87358715051046.54.71.320.78512857nynnnnnyy72.6061764706

chilton alan62m2134976.31.7225.79096809091076.841.010.96214080yynyynnyn118.0680967742

beasley martin49m21633112.81.7935.20489372991256.23.31.181.411677yynynnn0

hurditch john63m2144995.41.8129.11999023231167.440.925.712817281ynnyynnnn70.588546875

khaliq abdul71m2195274.61.6627.07214399771099.951.17212112759nynnynnyn52.3248099174proteinuria

moody adrian49m1292077.21.7525.2081632653887.94.61.82.48611864nnnnnnnyn100.4766976744

edis roy67m166183.81.7627.053202479310610.14.31.451.96411870nnnnnnnny117.56878125

forrest david62m1154787.31.7229.5091941591028.43.920.810112768nynnnnnnn82.9263564356

carr francis73m1363784.41.729.20415224911036.24.41.50.49618277yynyynnnn72.452125

harrison geoffrey74m1551972.21.6925.2792269178888.231.430.715516365nynynnnyy37.8141677419

twyford andrew31m122990.81.8526.53031409791057.44.61.930.48912082yynynnnyy136.7815280899

hannah william57m1282988.51.7130.26572278651077.83.41.430.88512259yynynnnyy106.2937058824

bray robert47m146183.41.6929.20065824031109.57.71.940.713914770ynnynnnyy68.634

aldridge paul60m1174380.21.7227.1092482423946.64.82.130.410912140nynnnnnyn72.400733945

wilson stephen52m11537100.91.831.14197530861218.44.81.921.510013070nynnnnnnn109.21416

spence raymond58m1322676.51.6727.4301696009977.83.20.930.914213066yynynynyy54.3365492958

piper keith57m1441370.21.724.2906574394957.64.31.061.210311354nynnnnyyy69.5797864078proteinuria

lancaster graham66m275974.71.5929.54788180851057.35.10.921.713311274ynyynynnn51.1217593985

saunders terence62m2204265.81.7820.7675798519410.151.1226513070nynnnnnny97.1208

shaibi saleh59m2554821.6729.402273297710974.70.850.97316397yynyynnnn111.9131506849

ellis stephen50m2173392.91.7829.32079282921009.54.50.943.6841370yynyynnyn122.4289285714

stirling brian48m2246891.7628.73192148761016.74.70.921.67613787nnnnnnnnn132.5163157895

watson neil61m2115082.21.8224.81584349721014.63.91.061.36512685nynnnnnny122.8826769231

james stephen51m264564.21.6423.8697204045877.73.80.88111113870ynnynnnyn63.3150810811

bingham peter62m21745102.91.8231.06508875741196.14.61.081.57915080ynnynnnyy124.9648860759

ratcliffe frederick56m2650111.61.834.444444444412310.55.31.481.786180100yynynnnnn134.0757209302

grey oliver75m1126381.11.7227.413466738810711.43.70.650.88815580ynnyynnnn73.6811931818

burkinshaw p60m245694.81.6236.12254229541145.64.61.131.68316880yynyynnny112.3893975904

stuart p44m1143090.71.7828.62643605611046.24.61.371.18912978nnnnnnnnn120.3354606742

bough b72m21755106.11.8232.031155657511783.51.022.215014578yynynynyy59.16136

platts i46m273994.61.7530.88979591841119.37.61.484.77812070nynnynnyn140.2263076923

brown d61m2160104.51.7832.98194672391286.43.71.361.25915678yynynnnyy172.1061864407

thabet s71m2185366.71.6225.41533302859913.35.70.763.68616271yynynnnnn65.8235930233

khan h78m2116782.71.6729.65326831371117.55.21.132.913015168nynnnnnnn48.5130923077

smythe a44m2539128.41.8537.51643535431288.34.30.835.87912070yynyynnnn191.9173670886

holmes b73m2116275.71.7225.5881557599978.241.442.18012969nynnnnnyy77.9804625

khan a53m2183579.41.6529.16437098261037.73.50.68214513667nynnynnyy58.5972

tyrell d60m22581231.9532.34714003941199.53.60.851.912214675ynnynnnyy99.206557377

wood k66m2125493.91.7530.66122448981088.44.50.763.59012972nnnnynnyy94.9642

gunnee a48m2246127.81.8139.00979823571267.53.60.771.896150100yynynnnnn150.64425

simpson p52m21141165.21.8846.74060660931777.15.31.151.89616796ynnynnnny186.263

mpundu c41m223995.81.829.567901234610410.73.91.061.69313975nnnnnnnnn125.4361935484

terry f57m265195.91.829.59876543211108.24.70.833.88310258nynnynnnn117.957

okane km57m2849100.91.7333.71312105321208.54.31.054.76414276yynyynnny160.951265625

frost b68m2244493.51.7331.240602759911410.64.10.822.813722586yynyynnyy60.4405839416

horne d64m22539801.727.68166089971049.23.81.1137118390ynnynnnyy105.3295774648

roberts s52m2448119.51.7539.02040816331267.34.11.143.19313872yynynnnny139.0825806452

scarlett a59m2134690.71.731.3840830451066.940.770.611516386yynynnnnn78.5777478261

ali a42m253756.71.5423.90791027158863.30.821.98310058nynnynnnn82.3447951807

burditt s49m21138133.71.7643.162448347113711.24.20.84.37717698yynynnnnn194.3511818182nephropathy

summerfield m35m113490.11.7529.42040816331106.93.90.922.98112570nnnnnnnnn143.6594444444

pryor j73m266795.71.6634.729278561206.73.11.020.99212363yynyynnnn85.7243152174

walton h77m2136470.21.6326.4217697316968.33.71.081.58314244yynynnnnn65.5397349398

buckle h78m2156376.41.6727.39431317011097.95.21.031.610513776ynnynnynn55.4882285714

rayner g53m2350961.7232.44997295841214.93.61.120.812514881yynynynnn82.18368

bethell a51m274496.61.7133.035805889112114.51.052.210413288yynynnnnn101.6807884615

webster h20m118272.71.8621.01399005678011.43.91.550.57011257nnnnnnnnn153.2931428571

ellis r58m2184081.91.631.99218751099.15.61.232.213016686yynyynnyn63.5418

singh a57m2134488.31.6930.91628444381147.55.60.956.312812469nynnynnyn70.4261484375

lee g58m210481001.7333.41240936881267.94.21.152.87315472nynynnnnn138.1643835616

gauntley b70m21852100.11.7632.31534090911148.23.91.212.18915971yynynnnyn96.8383146067

edge l53m2548160.51.7850.65648276731517.35.21.042.97712657nnnnnnnnn223.0533116883

chilvers d19m111865.61.7621.1776859504845.83.51.431.38010060nnnnnnnnn122.0406

bramley d69m22049102.51.735.46712802771187.931.090.918114963yynyynyyn49.4548342541

wigley g64m2361107.91.8132.93550257931067.63.60.861.611510874yynyynnny87.708626087

williamson r80m277390.61.6931.721578376111410.15.21.32.217413768ynnynnnyn38.4268965517

moody j70m2195178.11.7226.39940508381009.92.91.172.38214060yynynnyyn82.005

evans d53m225180.81.6131.1716368967988.43.91.011.68713777yynynnnnn99.384

bickerstaff n39m143570.71.7722.5669507485838.74.51.880.610112866nnnnnnnnn86.961

adnett-revill f73m2106379.31.7625.6004648761009.22.70.941.111611071nynnynnnn56.3371810345

hussain b56m2134379.21.727.40484429071126.33.50.991.48111667yynyynnny101.024

sharpe r51m274488.71.8326.48630893731046.23.91.421.316113370yynynnnny60.3104906832nephropathy

green e59m235684.41.6630.62853824941116.33.91.311.616513070yynyynnny50.9622545455

hall ap64m22143106.71.832.93209876541289.74.40.821.811212062nnynnnnny89.0563928571

mcallen k57m2453102.61.831.66666666671147.43.61.042.39512276nynnnnnyn110.2572

buckley m38m2137154.11.7351.48852283741537.14.41.091.611812276nynnnnnnn163.8422542373

pymm pa62m245879.71.727.57785467131037.74.71.123.511217391yynynnnyy68.2715892857microalbuminuria

ayres d71m2215070.91.6526.04224058771048.12.20.661.47414874nynynnnnn81.3146351351

parkin sj58m21642116.71.7737.249832423613512.66.50.975.98615481yynynnnyy136.8646744186

hussain j49m2544821.6829.0532879819110.58.35.21.074.78712880yynyynnnn105.4972413793

ladva s72m2135958.21.6122.45283746779012.13.90.80.86616879nnnynnnnn73.7552727273

ullah a68m216779.51.6329.92208965341097.42.90.521.411815981yynyynnny59.6654237288proteinuria

lamb d72m21656111.71.9429.67903071531207.62.40.830.513115475yynynnnyy71.3174656489

eckhardt a60m2114992.41.7530.17142857141076.95.11.32.19610060yynyyyyny94.71proteinuria

roberts ga81m2166579.81.6728.6134318191068.25.71.721.28013070nnnnnnnyy72.388575

parkin g45m25401101.833.95061728411912.66.50.975.99115494yynynnnnn141.2472527473

kidus a31m2823731.6726.1751945211989.86.21.23.17013378nnnnnnnnn139.8158571429

hamilton ss34m213382.41.6829.19501133791037.95.40.920.98812272ynnynnnnn122.0830909091

female

NameagesexDM typeDM durationage onsetweightheightBMIWCHbA1ctotal CholHDLTrigcreat(umol/l)sys BPdias BPBP RxStatinfibrateHTNIHDCVAPVDretinopaneuropaeMDRDethnic

Vickers Mavis60f285290.91.6533.38842975211196.24.11.162.211814183yynynnynn64.4311525424

Furness barbara76f2245263.71.6523.39761248858810.13.61.510.89818373yynynnnyn43.4928

Rafiq maqsood52f264683.61.5136.665058550112111.23.70.843.512016674yynyynnny64.09612pakistani

Rowland doris63f2954110.31.738.16608996541236.13.41.061.49614450yynynnnny92.4951671875

Wood lily74f2393567.51.5129.60396473841226.64.30.971.512212167ynnynnnny38.1778893443

Baker betty75f257062.11.5127.2356475593916.84.21.242.78312262yynynnnny50.845310241

Stott patricia56f2124484.81.5734.40301837811765.51.312.59414881ynyynnnyy79.2266553191

Lang christine50f22481281.7243.26663061111349.73.91.491.66613070yynynnnnn182.4872727273

Hopkins winifred63f2174694.71.6236.08443834781299.43.90.891.77713767yynynnnyy99.00885

Crookes elaine62f21052108.41.7336.21905175581247.52.70.751.26914464yynynnnny128.1146608696

Bailey dorothy55f228271169.55.82.171.512713262ynnynnnyy0afro carri

hatch lilian44f244150.31.5661.76035502961166.53.20.980.76511662nnnnnnnnn232.0816984615

Garner doreen56f255178.21.4835.70124178231187.75.20.93.75913874nynnnnnnn116.4013627119proteinuria

seymour mary61f2164575.61.4834.51424397371047.45.50.913.712313371yynynnnyy50.7654

king pauline73f2469107.11.6539.33884297521229.45.40.954.68417479yyyynnnnn89.3118375

didsbury valerie60f295189.41.7529.19183673471129.551.112.810618375yynynynnn70.5416603774

cooling lesley58f25881.71.6231.13092516381107.64.90.922.36212861yynynnnyy112.971333871

cooper diane66f2165090.41.5239.12742382271279.53.90.894.27815276yynyynnnn89.6663692308

watson ann66f2155193.21.6733.41819355312394.60.982.312812769ynnynnnyy56.332846875

judge mary61f275460.81.3732.3938409079967.24.71.373.58311063nynnnnnnn60.5029590361

wood freda68f2105869.41.5728.155300417998104.91.015.410011060yynynnnny52.241544

begum janat64f2361103.61.5244.84072022161327.93.12.225916486yynyynnyy31.7832proteinuriapakistani

holroyd barbara73f2205381.91.5235.44840720221455.93.61.21.313215570yynynnnyn43.4619102273

bi akhtar49f2292048.81.5221.1218836565928.85.11.123.16113269nynnnnnyn76.1124

bellis shelah54f219351061.641.4062512693.51.121.57510060yynynnnyn127.07704

everitt joan67f2105797.81.6137.73002584781268.33.90.752.69612068yynyynnnn77.752528125

crompton dawn44f2172795.41.5539.70863683661248.95.11.122.675160100nnnnnnnyn127.668096

burns joyce79f2166357.51.622.46093759010.25.41.431.810214570yynynnnyn35.951875

shakespeare christina57f2354103.61.640.4687513766.31.253.118310560ynnyyynny49.1259311475proteinuria

patterson evie73f276688.31.5437.232248271212684.51.790.79515779yynynnnyy65.1082373684

ahmed razina59f2104961.51.5724.950302243510374.60.9246511763nynnynnny80.1255115385

rothwell joan65f2956123.81.648.3593751436.73.71.273.79613055yynyynnnn101.119453125

richards brenda75f27583.41043.51.292.313572yynyyyn0

warren dorothy67f2364113.51.6243.24798049081166.62.71.071.26714268yynyynnnn129.2908992537

jan farooq71f2764741.5530.801248699312212.36.11.012.314070ynnyynn0

frost julie47f2740116.11.6741.62931621791379.25.61.262.56312670nnnnnnnny179.1837642857

hussain luftun32f223056.51.5224.4546398892937.73.40.870.96711868nnnnnnnnn95.2185223881

benton margaret70f2155561.11.5326.101072237210393.71.121.415362yynynnn0

naughton irene34f21024125.91.6247.97286998931278.85.30.992.77015490nnnynnnyn199.3230814286

ahmed fatima70f2155562.91.4928.3320571145986.63.81.1225118490yynynnnyn90.2615

webster evelyn83f297483.91.6132.36757841131105.83.51.040.917995yynyyny0

stacey maureen67f276090.21.635.2343751208.54.81.178311570yynynnnyy82.942160241

wilson carol61f285381.21.6828.76984126981096.95.30.991.95512060ynnyynnny121.9395163636

akhtar shaheen33f213279.81.6628.95921033531165.651.082.25911459nnnnnnnnn151.3068864407

williamson brenda64f285688.91.634.72656251207.23.90.82.98810075ynnyynnnn80.2706386364

dad jamilla60f2174358.51.6322.01814144310111.66.31.133.95510775nnnnnnnnn88.9625454545

white betty69f21257851.6331.992171327513073.71.072.110512045yynyyyyny60.0913571429

freebre lynne31f213084.51.6730.2986840691127.751.052.77012281nnnnnnnnn137.5653964286

gibbings rose61f1372461.71.6223.5101356501836.24.51.680.58712053ynnynnnyy58.5756396552

armitage lorna57f1342366.91.6723.98795223928210.84.51.650.811016070yynynnnyn52.7758895455

akinti sophie35f192677.31.6628.0519669038948.73.60.991.66611473nnnnnnnnn128.5727386364

greene tina39f1152479.31.6329.8468139561998.84.81.940.68712964nnnnnnnnn96.2496913793

hewitt doreen74f2116387.91.5735.66067588951245.23.10.951.77615768yynynnnnn79.8074171053

fish anne47f224599.61.6536.584022038611310.14.11.142.38115577yynynnnnn119.5587333333

modest beverley58f215774.31.629.02343751025.53.80.971.76315070yynynnnnn101.108147619

bi taseem53f2114278.71.5731.92827295221117.83.71.052.76712654yynynnnny106.8422977612proteimuria

khan waqar51f264566.11.6324.87861793821008.25.20.9526113681ynnynnnnn100.8290483607

beardall hilda83f2107348.71.4323.81534549378311.24.10.822.815414252yynyynnnn18.8454769481

needham brenda68f2563100.61.5939.7927297181237.74.91.021.47712080yynyynnyy98.3476051948

briggs rachel33f242975.31.6926.36462308741035.450.983.94913280nnnnnnnnn171.912205102

ellis maureen66f275981.31.5732.9830824781085.84.41.081.86013066yynyynnnn104.832285

farrar sylvia73f2271109.31.6142.16658307941198.94.71.470.87915469nynnnnnnn96.9152031646

benham c57f23541281.7243.26663061111357.34.90.491.57116582yynynnnnn156.4421408451

allen k66f2283881.21.6330.561933079911110.851.9118711365yynynnnyy33.5946545455

jones a66f216568.31.6824.1992630385937.35.70.972.77612769yynynnnny69.5285013158

harrison pauline67f2204768.21.626.640625997.43.91.122.314411753yynynnnyn36.1467104167

beal j66f2105678.31.5433.015685613110473.71.281.17511753nynnynnyn80.771148

kulkani m36f213596.71.6236.846517299212110.361.091.97115270nnnynnnnn148.0899211268

stafford g62f2144885.51.633.398437511213.45.11.551.99515075yynynnnnn73.3941

wildgoose e62f1243849.21.5719.9602417948758.24.92.230.87714570yynynnnyn52.1066337662

beanes j70f2125884.31.6232.12162780061097.13.10.93.38612678yynynnnnn71.7383197674

ludlam g56f265086.21.5436.3467701131195.44.11.241.95813070yynyynynn130.521662069

barrett j68f2204879.61.6728.541718957311892.60.881.24612368yynynnyyy130.2602086957

akhtar shamim51f254672.91.5231.55297783931067.56.41.234.17511769nynnnnnnn90.444114

wilks m27f21261301.650.7812512554.20.990.96912575nnnnnnnnn222.5854347826

begum kaniz61f2253684.21.6530.9274563821177.36.51.542.210113060nnnnnnnyy68.8560089109

hill m46f21135116.11.6443.16627007731108.53.70.873.27813878yynynnnny146.2815346154

kirk m57f11245115.31.6343.396439459512610.64.30.951.98716279yynynnnny115.0037982759

cutts m67f2105773.61.5829.48245473481017.34.30.922.46913366ynnynnnyy81.4096

dronfield j60f21842108.81.7336.352701393311711.46.21.042.68715881yynynnnyy104.5980689655

riley h57f21146881.5138.59479847381256.650.843.412316775yynynnnny62.084

mahmood u71f2155683.41.5733.8350440181136.84.61.212.28712480yynyynnnn69.1544172414

lack m61f135892.41.6733.13134210621017.84.92.21.363140100yynynnnny121.1386

naughton emily70f21159861.6531.58861340681129.44.10.842.79214567ynnynnnnn68.4120652174

dero f74f2175796.71.7232.68658734451099.74.11.78116716277yynyynnyy39.9556293413

akbar f71f23041511.5222.0740997239210.241.161.26512070nynnynnny56.6017615385

elliot e70f22050100.81.5243.62880886431258.55.71.39314015055yyyynynyn52.6932

bilton r59f2154474.51.5232.2454986151119.64.40.893.410013080yynyynynn63.0906975

revitt w79f24751461.6752.35038904231407.84.50.912.219014070ynnynnnyy49.0064368421

marshall m59f27521091.6341.02525499641197.62.90.9827912288yynyynnnn116.8445506329

weldon s57f1156101.51.7234.30908599241139.44.51.970.67013966yynnnnnnn125.825925

fisher m54f2252175.71.6862.2519841271515.44.31.5618414773nnnnnnnnn188.068025

james v59f1322795.81.5142.015701065713784.62.410.67915070ynnynnnyn102.6945683544

wrigley se49f2346128.91.6348.51518687191427.44.71.212.17613070ynnynnnnn161.3632953947

rooke tm47f224577.21.5731.31972899511009.54.41.291.37113369nnnnnnnnn105.7221380282

aslam k73f2145962.51.6722.41026928181016.84.41.113.17013668yynyynnny62.5433035714

roberts v63f2657100.41.6138.73307356971197.941.1638713465yynynnnnn92.9028896552

newton j52f2646112.51.7238.02731206061157.73.81.111.56214385yynynnnnn166.9427419355

tagg j40f25351041.6836.84807256241177.83.91.03266yynyynnnn164.7454545455

oxlade n57f2174096.51.6535.44536271811218.24.31.063.910014060nynnnnnny83.7393225

timpany s61f235856.71.622.1484375747.64.41.880.78211462nynnnnnnn57.111075

neil s65f21451101.41.5542.20603537981247.24.21.221.17515070yynynnnyy106.0137

begum z63f2144974.91.6228.53985672921176.33.81.170.77814377ynnynnnny77.3040019231

wright k36f1251183.41.6729.9042633296918.47.42.311.78313070nnnnnnnnn109.2560096386nephropathy

lally r60f295182.51.6231.43575674441049.13.31.530.57716382yynyyynyy89.6142857143

jeffcock js78f2146490.71.5239.25727146811107.93.50.961.99014070yynynnnnn65.3251633333

morgan p69f2125765.61.6723.5218186382947.46.62.1511.57311068ynnynnnnn66.7057643836

goodwin b74f11460621.5426.1426884804867.24.61.6417811877nnnnnnnnn54.8485384615

willyeo p57f2174088.81.6134.25793757961118.34.31.611.112113961nynnyyyyy63.6839107438

taylor s52f2232946.61.3425.9523279127729.24.92.70.810614855yynynnnnn40.4470415094

hall j67f2105778.21.5831.325108155711513.14.30.972.77917490yynyyynnn75.5486240506

thackeray t69f276262.61.5227.0948753463868.53.60.981.410213869yynynnnnn45.55715

khan rn43f283573.31.5331.312742962110410.14.80.814.46414289ynnynnnny116.1501492188

stansall j53f284575.11.5730.46776745511085.94.30.793.67212080yynynnnny94.87476875

kennedy m61f225959.11.5624.2850098619928.65.81.052.46217285nynynnnnn78.731208871

bi z49f249851.5933.622087733911510.24.81.163.15516865nynynnnnn147.0353181818

summers j47f2146117.71.7438.8756771041187.45.21.1517513360nnnnnnnnn152.588634

samwell i63f2125185.61.4441.280864197511010.14.21.2529211577nynnnnynn74.9032565217

stones m75f2185766.91.4930.13377775781077.35.11.025.712618791yynynynyy36.0821964286

fatima p56f274996.81.637.81251279.84.70.8416415670yynynnnyy132.830775

hague d75f21263103.41.640.39062513513.38.60.9710.99916380yynyyyynn70.9778333333

lees g71f2145798.61.5740.00162278391168.43.50.73414113359yynyynnnn50.446487234

khan h58f2154392.91.7331.04012830371218.74.50.961.96112076yynynnnny130.5640967213

murcott b66f216556.41.5423.7814133918896.33.71.131.28612064nynnnnnnn50.7383581395

clancy m74f256980.41.5433.90116377131068.45.31.371.57214687nynnnynyy77.05335

kent p59f212471181.6742.31058840413011.96.81.322.86416479yynyyynny156.138890625

carr s65f2105590.81.4443.78858024691249.14.21.12.410812555yynynnnny65.9245833333

roberts v44f2341120.11.5251.98234072021378.54.70.882.36016189yynynnnnn200.90328

malik r75f2156080.31.5632.99638395791138.93.71.21.66215973yynynynnn88.0159233871

matthews i61f2655103.81.5244.927285318613273.51.011.415316981yynynnnyn56.0347proteinuria

ADA study cohort

NameagesexDM typeDM durationage osetweightheightBMIWCHbA1ctotal CholHDLTrigcreat(umol/l)sys BPdias BPBP RxStatinfibrateHTNIHDCVAPVDretinopaneuropaeMDRDethnic

Simpson Donald76m2175731.5231.5962603878986.15.41.361.311213460yynynnnny43.6122857143

Hayes Philip62m28541051.7534.28571428571177.66.10.984.110415460ynnyynnnn96.8625

Wigfield Alan42m26361251.7839.45208938271237.63.91.37215571yynynnnnn209.2708333333

Simpson colin81m2117082.11.6430.52498512791105.93.91.022.29917070ynnynnyyy60.1817878788

Smithson harry72m287.61.7229.61060032451205.84.71.416116070ynnynnnyn45.5084720497

Yafai m73m2274663.91.5128.0250866191057.241.35111712772yynyynnyn45.0085384615arab

Hind george58m21147105.81.6240.3139765281259.52.80.960.68215272yynyynnyy130.134

Reed derek73m2195488.61.7329.603394700810810.32.80.831.316514873yynyyyyyy44.2516727273

Allsebrook godfrey68m2194995.51.6136.84271440151295.22.92.190810060yynynynyy9.3144052863

Fazal Kalsoum72m2195394.31.6235.932022557512893.10.734.19111460yynynynyy86.6730989011pakistani

Staniland stephen50m2173392.81.6932.491859528711410.540.743.88114380yynynnnnn126.8266666667

Brammer roger56m21145761.7524.81632653061016.33.90.774.19713866nynnynynn80.9517525773

Ward david57m22532105.71.6638.35825228631307.85.11.21.816016590yynyynnny67.44320625

khan dawood45m244184.21.7427.81080724011028.85.31.223.27810965yynyynnnn126.1380769231pakistaniproteinuria

singh gucharan59m2164373.21.6626.5640876761067.83.51.071.710312268yynyynnnn70.8050097087

trainor steven40m2535114.81.7637.06095041321299.23.91.211.86511566yynynnnnn217.2369230769

Wallis roger62m21547127.41.8537.22425127831456.64.40.972.49415769yynyynyny130.0293191489

patterson kenneth78m2911.828.08641975311137.14.31.151.318817784ynnynnnyy36.9130851064proteinuria

marshall elsie72m2171115.61.645.156251305.94.51.441.98117074ynnynnnnn119.3677037037

shepard allan36m2432100.91.7134.50634383231155.95.21.225.88314888yynynnnyn155.5075662651

margerrison raymond71m2106191.71.7230.99648458631146.34.11.331.17516877ynnynnnnn103.76772

nortcliff william67m2364105.31.8530.76698319941357.45.11.061.97813386yynyyynny121.2165

ali maqsood61m2154686.51.7727.61020141081088.83.50.751.911014275yynyynynana76.4109545455

thornton peter51m274481.51.4936.71005810551217.14.51.650.810010365yynynnnnn89.21805

priestley colin55m2183795.11.7730.35526189791136.73.40.971.58312871nynnynnnn119.791626506

murdoch philip45m254082.31.7227.819091400810110.95.81.371.48615895ynnynnnnn111.8227325581

campbell asher70m276385.11.5535.42143600421106.74.21.451.79814378yynynynnn74.7664285714

stansall roy59m21445110.11.7535.95102040821318.25.61.52.19717070ynnynnnyn113.085185567

whittaker brian63m2125199.91.8828.26505205981258.53.70.981.86317494yynynynnn150.183

ellis malcolm61m2952152.31.847.00617283951506.43.50.95311314580yynyynnyy130.9645221239proteinuria

grey burnice71m2304198.91.5541.16545265351196.34.60.961.310114786yynynnnnn83.1053762376

smith lesley77m2146361.41.6722.01584854249784.40.912.29414060yynyynyyn50.6158085106

ward james21m2120130.21.8438.45699432891367.95.61.640.77312456nnnnnnnnn261.0599178082

dawson alan73m21063110.31.7436.43149689521297.24.30.881.510113878ynnynnnnn89.9982475248proteinuria

ruban tareq51m2123988.31.7827.86895593991069.43.30.9329513475nynnnnnnn101.7494842105

rajah saleh75m286766.81.6325.1420828785996.540.850.613015870ynnyynnnn41.082

majid nazir71m2145762.11.4828.35098612131068.63.41.181.66713570ynnyynnyy78.6630895522

cox alan69m21851109.31.737.82006920421209.77.20.8517.113014080yyyyynnnn73.4243769231

everitt geoffrey59m2124784.61.6730.33454049981197.65.11.173.927713492yynyynnnn30.4285126354

hussein saffder39m263372.71.7523.73877551029112.83.40.941.87711473nnnnnnnnn117.2924805195

rowbotham ronald74m2215365.71.7122.4684518313958.64.11.011.521112960ynnyynnyy25.2773744076proteinuria

pendall brian62m23329117.21.7936.57813426551228.13.41.350.89611573yynynnnyy117.12675

khan abbas36m253182.91.7327.69888736681035.651.191.78911270nnnnnnnnn119.1524494382

butler james59m2104978.61.7326.26215376391056.17.72.630.913570ynnynnnnnproteinuria

ellis tony60m215981.91.7227.6838831801103105.916.28916395yynynynnn90.5501123596

khan lalmar59m295099.61.7333.2787597314124114.40.962.38313269yynyynnyy119.556

din zakavath65m2135266.91.6424.87358715051046.54.71.320.78512857nynnnnnyy72.6061764706

chilton alan62m2134976.31.7225.79096809091076.841.010.96214080yynyynnyn118.0680967742

beasley martin49m21633112.81.7935.20489372991256.23.31.181.411677yynynnn

hurditch john63m2144995.41.8129.11999023231167.440.925.712817281ynnyynnnn70.588546875

khaliq abdul71m2195274.61.6627.07214399771099.951.17212112759nynnynnyn52.3248099174proteinuria

lancaster graham66m275974.71.5929.54788180851057.35.10.921.713311274ynyynynnn51.1217593985

saunders terence62m2204265.81.7820.7675798519410.151.1226513070nynnnnnny97.1208

shaibi saleh59m2554821.6729.402273297710974.70.850.97316397yynyynnnn111.9131506849

ellis stephen50m2173392.91.7829.32079282921009.54.50.943.6841370yynyynnyn122.4289285714

stirling brian48m2246891.7628.73192148761016.74.70.921.67613787nnnnnnnnn132.5163157895

watson neil61m2115082.21.8224.81584349721014.63.91.061.36512685nynnnnnny122.8826769231

james stephen51m264564.21.6423.8697204045877.73.80.88111113870ynnynnnyn63.3150810811

bingham peter62m21745102.91.8231.06508875741196.14.61.081.57915080ynnynnnyy124.9648860759

ratcliffe frederick56m2650111.61.834.444444444412310.55.31.481.786180100yynynnnnn134.0757209302

burkinshaw p60m245694.81.6236.12254229541145.64.61.131.68316880yynyynnny112.3893975904

bough b72m21755106.11.8232.031155657511783.51.022.215014578yynynynyy59.16136

platts i46m273994.61.7530.88979591841119.37.61.484.77812070nynnynnyn140.2263076923

brown d61m2160104.51.7832.98194672391286.43.71.361.25915678yynynnnyy172.1061864407

thabet s71m2185366.71.6225.41533302859913.35.70.763.68616271yynynnnnn65.8235930233

khan h78m2116782.71.6729.65326831371117.55.21.132.913015168nynnnnnnn48.5130923077

smythe a44m2539128.41.8537.51643535431288.34.30.835.87912070yynyynnnn191.9173670886

holmes b73m2116275.71.7225.5881557599978.241.442.18012969nynnnnnyy77.9804625

khan a53m2183579.41.6529.16437098261037.73.50.68214513667nynnynnyy58.5972

tyrell d60m22581231.9532.34714003941199.53.60.851.912214675ynnynnnyy99.206557377

wood k66m2125493.91.7530.66122448981088.44.50.763.59012972nnnnynnyy94.9642

gunnee a48m2246127.81.8139.00979823571267.53.60.771.896150100yynynnnnn150.64425

simpson p52m21141165.21.8846.74060660931777.15.31.151.89616796ynnynnnny186.263

mpundu c41m223995.81.829.567901234610410.73.91.061.69313975nnnnnnnnn125.4361935484

terry f57m265195.91.829.59876543211108.24.70.833.88310258nynnynnnn117.957

okane km57m2849100.91.7333.71312105321208.54.31.054.76414276yynyynnny160.951265625

frost b68m2244493.51.7331.240602759911410.64.10.822.813722586yynyynnyy60.4405839416

horne d64m22539801.727.68166089971049.23.81.1137118390ynnynnnyy105.3295774648

roberts s52m2448119.51.7539.02040816331267.34.11.143.19313872yynynnnny139.0825806452

scarlett a59m2134690.71.731.3840830451066.940.770.611516386yynynnnnn78.5777478261

ali a42m253756.71.5423.90791027158863.30.821.98310058nynnynnnn82.3447951807

burditt s49m21138133.71.7643.162448347113711.24.20.84.37717698yynynnnnn194.3511818182nephropathy

pryor j73m266795.71.6634.729278561206.73.11.020.99212363yynyynnnn85.7243152174

walton h77m2136470.21.6326.4217697316968.33.71.081.58314244yynynnnnn65.5397349398

buckle h78m2156376.41.6727.39431317011097.95.21.031.610513776ynnynnynn55.4882285714

rayner g53m2350961.7232.44997295841214.93.61.120.812514881yynynynnn82.18368

bethell a51m274496.61.7133.035805889112114.51.052.210413288yynynnnnn101.6807884615

ellis r58m2184081.91.631.99218751099.15.61.232.213016686yynyynnyn63.5418

singh a57m2134488.31.6930.91628444381147.55.60.956.312812469nynnynnyn70.4261484375

lee g58m210481001.7333.41240936881267.94.21.152.87315472nynynnnnn138.1643835616

gauntley b70m21852100.11.7632.31534090911148.23.91.212.18915971yynynnnyn96.8383146067

edge l53m2548160.51.7850.65648276731517.35.21.042.97712657nnnnnnnnn223.0533116883

bramley d69m22049102.51.735.46712802771187.931.090.918114963yynyynyyn49.4548342541

wigley g64m2361107.91.8132.93550257931067.63.60.861.611510874yynyynnny87.708626087

williamson r80m277390.61.6931.721578376111410.15.21.32.217413768ynnynnnyn38.4268965517

moody j70m2195178.11.7226.39940508381009.92.91.172.38214060yynynnyyn82.005

evans d53m225180.81.6131.1716368967988.43.91.011.68713777yynynnnnn99.384

adnett-revill f73m2106379.31.7625.6004648761009.22.70.941.111611071nynnynnnn56.3371810345

hussain b56m2134379.21.727.40484429071126.33.50.991.48111667yynyynnny101.024

sharpe r51m274488.71.8326.48630893731046.23.91.421.316113370yynynnnny60.3104906832nephropathy

green e59m235684.41.6630.62853824941116.33.91.311.616513070yynyynnny50.9622545455

hall ap64m22143106.71.832.93209876541289.74.40.821.811212062nnynnnnny89.0563928571

mcallen k57m2453102.61.831.66666666671147.43.61.042.39512276nynnnnnyn110.2572

buckley m38m2137154.11.7351.48852283741537.14.41.091.611812276nynnnnnnn163.8422542373

pymm pa62m245879.71.727.57785467131037.74.71.123.511217391yynynnnyy68.2715892857microalbuminuria

ayres d71m2215070.91.6526.04224058771048.12.20.661.47414874nynynnnnn81.3146351351

parkin sj58m21642116.71.7737.249832423613512.66.50.975.98615481yynynnnyy136.8646744186

hussain j49m2544821.6829.0532879819110.58.35.21.074.78712880yynyynnnn105.4972413793

ladva s72m2135958.21.6122.45283746779012.13.90.80.86616879nnnynnnnn73.7552727273

ullah a68m216779.51.6329.92208965341097.42.90.521.411815981yynyynnny59.6654237288proteinuria

lamb d72m21656111.71.9429.67903071531207.62.40.830.513115475yynynnnyy71.3174656489

eckhardt a60m2114992.41.7530.17142857141076.95.11.32.19610060yynyyyyny94.71proteinuria

roberts ga81m2166579.81.6728.6134318191068.25.71.721.28013070nnnnnnnyy72.388575

parkin g45m25401101.833.95061728411912.66.50.975.99115494yynynnnnn141.2472527473

kidus a31m2823731.6726.1751945211989.86.21.23.17013378nnnnnnnnn139.8158571429

hamilton ss34m213382.41.6829.19501133791037.95.40.920.98812272ynnynnnnn122.0830909091

Vickers Mavis60f285290.91.6533.38842975211196.24.11.162.211814183yynynnynn64.4311525424

Furness barbara76f2245263.71.6523.39761248858810.13.61.510.89818373yynynnnyn43.4928

Rafiq maqsood52f264683.61.5136.665058550112111.23.70.843.512016674yynyynnny64.09612pakistani

Rowland doris63f2954110.31.738.16608996541236.13.41.061.49614450yynynnnny92.4951671875

Wood lily74f2393567.51.5129.60396473841226.64.30.971.512212167ynnynnnny38.1778893443

Baker betty75f257062.11.5127.2356475593916.84.21.242.78312262yynynnnny50.845310241

Stott patricia56f2124484.81.5734.40301837811765.51.312.59414881ynyynnnyy79.2266553191

Lang christine50f22481281.7243.26663061111349.73.91.491.66613070yynynnnnn182.4872727273

Hopkins winifred63f2174694.71.6236.08443834781299.43.90.891.77713767yynynnnyy99.00885

Crookes elaine62f21052108.41.7336.21905175581247.52.70.751.26914464yynynnnny128.1146608696

Bailey dorothy55f228271169.55.82.171.512713262ynnynnnyyafro carri

hatch lilian44f2150.31.5661.76035502961166.53.20.980.76511662nnnnnnnnn232.0816984615

Garner doreen56f255178.21.4835.70124178231187.75.20.93.75913874nynnnnnnn116.4013627119proteinuria

seymour mary61f2164575.61.4834.51424397371047.45.50.913.712313371yynynnnyy50.7654

king pauline73f2469107.11.6539.33884297521229.45.40.954.68417479yyyynnnnn89.3118375

didsbury valerie60f295189.41.7529.19183673471129.551.112.810618375yynynynnn70.5416603774

cooling lesley58f281.71.6231.13092516381107.64.90.922.36212861yynynnnyy112.971333871

cooper diane66f2165090.41.5239.12742382271279.53.90.894.27815276yynyynnnn89.6663692308

watson ann66f2155193.21.6733.41819355312394.60.982.312812769ynnynnnyy56.332846875

judge mary61f275460.81.3732.3938409079967.24.71.373.58311063nynnnnnnn60.5029590361

wood freda68f2105869.41.5728.155300417998104.91.015.410011060yynynnnny52.241544

begum janat64f2361103.61.5244.84072022161327.93.12.225916486yynyynnyy31.7832proteinuriapakistani

holroyd barbara73f2205381.91.5235.44840720221455.93.61.21.313215570yynynnnyn43.4619102273

bi akhtar49f2292048.81.5221.1218836565928.85.11.123.16113269nynnnnnyn76.1124

bellis shelah54f219351061.641.4062512693.51.121.57510060yynynnnyn127.07704

everitt joan67f2105797.81.6137.73002584781268.33.90.752.69612068yynyynnnn77.752528125

crompton dawn44f2172795.41.5539.70863683661248.95.11.122.675160100nnnnnnnyn127.668096

burns joyce79f2166357.51.622.46093759010.25.41.431.810214570yynynnnyn35.951875

shakespeare christina57f2354103.61.640.4687513766.31.253.118310560ynnyyynny49.1259311475proteinuria

patterson evie73f276688.31.5437.232248271212684.51.790.79515779yynynnnyy65.1082373684

ahmed razina59f2104961.51.5724.950302243510374.60.9246511763nynnynnny80.1255115385

rothwell joan65f2956123.81.648.3593751436.73.71.273.79613055yynyynnnn101.119453125

richards brenda75f283.41043.51.292.313572yynyyyn

warren dorothy67f2364113.51.6243.24798049081166.62.71.071.26714268yynyynnnn129.2908992537

jan farooq71f2764741.5530.801248699312212.36.11.012.314070ynnyynn

frost julie47f2740116.11.6741.62931621791379.25.61.262.56312670nnnnnnnny179.1837642857

hussain luftun32f223056.51.5224.4546398892937.73.40.870.96711868nnnnnnnnn95.2185223881

benton margaret70f2155561.11.5326.101072237210393.71.121.415362yynynnn

naughton irene34f21024125.91.6247.97286998931278.85.30.992.77015490nnnynnnyn199.3230814286

ahmed fatima70f2155562.91.4928.3320571145986.63.81.1225118490yynynnnyn90.2615

webster evelyn83f297483.91.6132.36757841131105.83.51.040.917995yynyyny

stacey maureen67f276090.21.635.2343751208.54.81.178311570yynynnnyy82.942160241

wilson carol61f285381.21.6828.76984126981096.95.30.991.95512060ynnyynnny121.9395163636

akhtar shaheen33f213279.81.6628.95921033531165.651.082.25911459nnnnnnnnn151.3068864407

williamson brenda64f285688.91.634.72656251207.23.90.82.98810075ynnyynnnn80.2706386364

dad jamilla60f2174358.51.6322.01814144310111.66.31.133.95510775nnnnnnnnn88.9625454545

white betty69f21257851.6331.992171327513073.71.072.110512045yynyyyyny60.0913571429

freebre lynne31f213084.51.6730.2986840691127.751.052.77012281nnnnnnnnn137.5653964286

hewitt doreen74f2116387.91.5735.66067588951245.23.10.951.77615768yynynnnnn79.8074171053

fish anne47f224599.61.6536.584022038611310.14.11.142.38115577yynynnnnn119.5587333333

modest beverley58f215774.31.629.02343751025.53.80.971.76315070yynynnnnn101.108147619

bi taseem53f2114278.71.5731.92827295221117.83.71.052.76712654yynynnnny106.8422977612proteimuria

khan waqar51f264566.11.6324.87861793821008.25.20.9526113681ynnynnnnn100.8290483607

beardall hilda83f2107348.71.4323.81534549378311.24.10.822.815414252yynyynnnn18.8454769481

needham brenda68f2563100.61.5939.7927297181237.74.91.021.47712080yynyynnyy98.3476051948

briggs rachel33f242975.31.6926.36462308741035.450.983.94913280nnnnnnnnn171.912205102

ellis maureen66f275981.31.5732.9830824781085.84.41.081.86013066yynyynnnn104.832285

farrar sylvia73f2271109.31.6142.16658307941198.94.71.470.87915469nynnnnnnn96.9152031646

benham c57f23541281.7243.26663061111357.34.90.491.57116582yynynnnnn156.4421408451

allen k66f2283881.21.6330.561933079911110.851.9118711365yynynnnyy33.5946545455

jones a66f216568.31.6824.1992630385937.35.70.972.77612769yynynnnny69.5285013158

harrison pauline67f2204768.21.626.640625997.43.91.122.314411753yynynnnyn36.1467104167

beal j66f2105678.31.5433.015685613110473.71.281.17511753nynnynnyn80.771148

kulkani m36f213596.71.6236.846517299212110.361.091.97115270nnnynnnnn148.0899211268

stafford g62f2144885.51.633.398437511213.45.11.551.99515075yynynnnnn73.3941

beanes j70f2125884.31.6232.12162780061097.13.10.93.38612678yynynnnnn71.7383197674

ludlam g56f265086.21.5436.3467701131195.44.11.241.95813070yynyynynn130.521662069

barrett j68f2204879.61.6728.541718957311892.60.881.24612368yynynnyyy130.2602086957

akhtar shamim51f254672.91.5231.55297783931067.56.41.234.17511769nynnnnnnn90.444114

wilks m27f21261301.650.7812512554.20.990.96912575nnnnnnnnn222.5854347826

begum kaniz61f2253684.21.6530.9274563821177.36.51.542.210113060nnnnnnnyy68.8560089109

hill m46f21135116.11.6443.16627007731108.53.70.873.27813878yynynnnny146.2815346154

cutts m67f2105773.61.5829.48245473481017.34.30.922.46913366ynnynnnyy81.4096

dronfield j60f21842108.81.7336.352701393311711.46.21.042.68715881yynynnnyy104.5980689655

riley h57f21146881.5138.59479847381256.650.843.412316775yynynnnny62.084

mahmood u71f2155683.41.5733.8350440181136.84.61.212.28712480yynyynnnn69.1544172414

naughton emily70f21159861.6531.58861340681129.44.10.842.79214567ynnynnnnn68.4120652174

dero f74f2175796.71.7232.68658734451099.74.11.78116716277yynyynnyy39.9556293413

akbar f71f23041511.5222.0740997239210.241.161.26512070nynnynnny56.6017615385

elliot e70f22050100.81.5243.62880886431258.55.71.39314015055yyyynynyn52.6932

bilton r59f2154474.51.5232.2454986151119.64.40.893.410013080yynyynynn63.0906975

revitt w79f24751461.6752.35038904231407.84.50.912.219014070ynnynnnyy49.0064368421

marshall m59f27521091.6341.02525499641197.62.90.9827912288yynyynnnn116.8445506329

fisher m54f2252175.71.6862.2519841271515.44.31.5618414773nnnnnnnnn188.068025

wrigley se49f2346128.91.6348.51518687191427.44.71.212.17613070ynnynnnnn161.3632953947

rooke tm47f224577.21.5731.31972899511009.54.41.291.37113369nnnnnnnnn105.7221380282

aslam k73f2145962.51.6722.41026928181016.84.41.113.17013668yynyynnny62.5433035714

roberts v63f2657100.41.6138.73307356971197.941.1638713465yynynnnnn92.9028896552

newton j52f2646112.51.7238.02731206061157.73.81.111.56214385yynynnnnn166.9427419355

tagg j40f25351041.6836.84807256241177.83.91.03266yynyynnnn164.7454545455

oxlade n57f2174096.51.6535.44536271811218.24.31.063.910014060nynnnnnny83.7393225

timpany s61f235856.71.622.1484375747.64.41.880.78211462nynnnnnnn57.111075

neil s65f21451101.41.5542.20603537981247.24.21.221.17515070yynynnnyy106.0137

begum z63f2144974.91.6228.53985672921176.33.81.170.77814377ynnynnnny77.3040019231

lally r60f295182.51.6231.43575674441049.13.31.530.57716382yynyyynyy89.6142857143

jeffcock js78f2146490.71.5239.25727146811107.93.50.961.99014070yynynnnnn65.3251633333

morgan p69f2125765.61.6723.5218186382947.46.62.1511.57311068ynnynnnnn66.7057643836

willyeo p57f2174088.81.6134.25793757961118.34.31.611.112113961nynnyyyyy63.6839107438

taylor s52f2232946.61.3425.9523279127729.24.92.70.810614855yynynnnnn40.4470415094

hall j67f2105778.21.5831.325108155711513.14.30.972.77917490yynyyynnn75.5486240506

thackeray t69f276262.61.5227.0948753463868.53.60.981.410213869yynynnnnn45.55715

khan rn43f283573.31.5331.312742962110410.14.80.814.46414289ynnynnnny116.1501492188

stansall j53f284575.11.5730.46776745511085.94.30.793.67212080yynynnnny94.87476875

kennedy m61f225959.11.5624.2850098619928.65.81.052.46217285nynynnnnn78.731208871

bi z49f2851.5933.622087733911510.24.81.163.15516865nynynnnnn147.0353181818

summers j47f2146117.71.7438.8756771041187.45.21.1517513360nnnnnnnnn152.588634

samwell i63f2125185.61.4441.280864197511010.14.21.2529211577nynnnnynn74.9032565217

stones m75f2185766.91.4930.13377775781077.35.11.025.712618791yynynynyy36.0821964286

fatima p56f274996.81.637.81251279.84.70.8416415670yynynnnyy132.830775

hague d75f21263103.41.640.39062513513.38.60.9710.99916380yynyyyynn70.9778333333

lees g71f2145798.61.5740.00162278391168.43.50.73414113359yynyynnnn50.446487234

khan h58f2154392.91.7331.04012830371218.74.50.961.96112076yynynnnny130.5640967213

murcott b66f216556.41.5423.7814133918896.33.71.131.28612064nynnnnnnn50.7383581395

clancy m74f256980.41.5433.90116377131068.45.31.371.57214687nynnnynyy77.05335

kent p59f212471181.6742.31058840413011.96.81.322.86416479yynyyynny156.138890625

carr s65f2105590.81.4443.78858024691249.14.21.12.410812555yynynnnny65.9245833333

roberts v44f2341120.11.5251.98234072021378.54.70.882.36016189yynynnnnn200.90328

malik r75f2156080.31.5632.99638395791138.93.71.21.66215973yynynynnn88.0159233871

matthews i61f2655103.81.5244.927285318613273.51.011.415316981yynynnnyn56.0347proteinuria

edis roy67m166183.81.7627.053202479310610.14.31.451.96411870nnnnnnnny117.56878125

forrest david62m1154787.31.7229.5091941591028.43.920.810112768nynnnnnnn82.9263564356

carr francis73m1363784.41.729.20415224911036.24.41.50.49618277yynyynnnn72.452125

aldridge paul60m1174380.21.7227.1092482423946.64.82.130.410912140nynnnnnyn72.400733945

wilson stephen52m11537100.91.831.14197530861218.44.81.921.510013070nynnnnnnn109.21416

grey oliver75m1126381.11.7227.413466738810711.43.70.650.88815580ynnyynnnn73.6811931818

stuart p44m1143090.71.7828.62643605611046.24.61.371.18912978nnnnnnnnn120.3354606742

summerfield m35m113490.11.7529.42040816331106.93.90.922.98112570nnnnnnnnn143.6594444444

bickerstaff n39m143570.71.7722.5669507485838.74.51.880.610112866nnnnnnnnn86.961

spence raymond58m1322676.51.6727.4301696009977.83.20.930.914213066yynynynyy54.3365492958

hannah william57m1282988.51.7130.26572278651077.83.41.430.88512259yynynnnyy106.2937058824

wildgoose e62f1243849.21.5719.9602417948758.24.92.230.87714570yynynnnyn52.1066337662

kirk m57f11245115.31.6343.396439459512610.64.30.951.98716279yynynnnny115.0037982759

lack m61f135892.41.6733.13134210621017.84.92.21.363140100yynynnnny121.1386

weldon s57f1156101.51.7234.30908599241139.44.51.970.67013966yynnnnnnn125.825925

goodwin b74f11460621.5426.1426884804867.24.61.6417811877nnnnnnnnn54.8485384615

james v59f1322795.81.5142.015701065713784.62.410.67915070ynnynnnyn102.6945683544

study male

NameatpidfagesexDM typeDM durationage osetweightheightBMIWCHbA1ctotal CholHDLTrigcreat(umol/l)sys BPdias BPBP RxStatinfibrateHTNIHDCVAPVDretinopaneuropaeMDRDethnic

ward jamesnn21m2120130.21.8438.45699432891367.95.61.640.77312456nnnnnnnnn261.0599178082

kidus ayy31m2823731.6726.1751945211989.86.21.23.17013378nnnnnnnnn139.8158571429

hamilton ssyy34m213382.41.6829.19501133791037.95.40.920.98812272ynnynnnnn122.0830909091

summerfield myy35m113490.11.7529.42040816331106.93.90.922.98112570nnnnnnnnn143.6594444444

khan abbasnn36m253182.91.7327.69888736681035.651.191.78911270nnnnnnnnn119.1524494382

shepard allanyy36m2432100.91.7134.50634383231155.95.21.225.88314888yynynnnyn155.5075662651

buckley mnn38m2137154.11.7351.48852283741537.14.41.091.611812276nynnnnnnn163.8422542373

bickerstaff nnn39m143570.71.7722.5669507485838.74.51.880.610112866nnnnnnnnn86.961

hussein saffderyn39m263372.71.7523.73877551029112.83.40.941.87711473nnnnnnnnn117.2924805195

trainor stevenyy40m2535114.81.7637.06095041321299.23.91.211.86511566yynynnnnn217.2369230769

mpundu cyy41m223995.81.829.567901234610410.73.91.061.69313975nnnnnnnnn125.4361935484

ali ayn42m253756.71.5423.90791027158863.30.821.98310058nynnynnnn82.3447951807

Wigfield Alanyy42m26361251.7839.45208938271237.63.91.37215571yynynnnnn209.2708333333

smythe ayy44m2539128.41.8537.51643535431288.34.30.835.87912070yynyynnnn191.9173670886

stuart pnn44m1143090.71.7828.62643605611046.24.61.371.18912978nnnnnnnnn120.3354606742

khan dawoodyy45m244184.21.7427.81080724011028.85.31.223.27810965yynyynnnn126.1380769231pakistaniproteinuria

murdoch philipny45m254082.31.7227.819091400810110.95.81.371.48615895ynnynnnnn111.8227325581

parkin gyy45m25401101.833.95061728411912.66.50.975.99115494yynynnnnn141.2472527473

platts iyy46m273994.61.7530.88979591841119.37.61.484.77812070nynnynnyn140.2263076923

gunnee ayy48m2246127.81.8139.00979823571267.53.60.771.896150100yynynnnnn150.64425

stirling brianyy48m2246891.7628.73192148761016.74.70.921.67613787nnnnnnnnn132.5163157895

beasley martinyy49m21633112.81.7935.20489372991256.23.31.181.411677yynynnn

burditt syy49m21138133.71.7643.162448347113711.24.20.84.37717698yynynnnnn194.3511818182nephropathy

hussain jyy49m2544821.6829.0532879819110.58.35.21.074.78712880yynyynnnn105.4972413793

ellis stephenyy50m2173392.91.7829.32079282921009.54.50.943.6841370yynyynnyn122.4289285714

Staniland stephenyy50m2173392.81.6932.491859528711410.540.743.88114380yynynnnnn126.8266666667

bethell ayy51m274496.61.7133.035805889112114.51.052.210413288yynynnnnn101.6807884615

james stephenyn51m264564.21.6423.8697204045877.73.80.88111113870ynnynnnyn63.3150810811

ruban tareqyy51m2123988.31.7827.86895593991069.43.30.9329513475nynnnnnnn101.7494842105

sharpe ryy51m274488.71.8326.48630893731046.23.91.421.316113370yynynnnny60.3104906832nephropathy

thornton peteryy51m274481.51.4936.71005810551217.14.51.650.810010365yynynnnnn89.21805

roberts syy52m2448119.51.7539.02040816331267.34.11.143.19313872yynynnnny139.0825806452

simpson pyy52m21141165.21.8846.74060660931777.15.31.151.89616796ynnynnnny186.263

wilson stephenyy52m11537100.91.831.14197530861218.44.81.921.510013070nynnnnnnn109.21416

edge lyy53m2548160.51.7850.65648276731517.35.21.042.97712657nnnnnnnnn223.0533116883

evans dyy53m225180.81.6131.1716368967988.43.91.011.68713777yynynnnnn99.384

khan ayy53m2183579.41.6529.16437098261037.73.50.68214513667nynnynnyy58.5972

rayner gyy53m2350961.7232.44997295841214.93.61.120.812514881yynynynnn82.18368

priestley colinyy55m2183795.11.7730.35526189791136.73.40.971.58312871nynnynnnn119.791626506

Brammer rogeryy56m21145761.7524.81632653061016.33.90.774.19713866nynnynynn80.9517525773

hussain byy56m2134379.21.727.40484429071126.33.50.991.48111667yynyynnny101.024

ratcliffe frederickyy56m2650111.61.834.444444444412310.55.31.481.786180100yynynnnnn134.0757209302

hannah williamyy57m1282988.51.7130.26572278651077.83.41.430.88512259yynynnnyy106.2937058824

mcallen kyy57m2453102.61.831.66666666671147.43.61.042.39512276nynnnnnyn110.2572

okane kmyy57m2849100.91.7333.71312105321208.54.31.054.76414276yynyynnny160.951265625

singh ayy57m2134488.31.6930.91628444381147.55.60.956.312812469nynnynnyn70.4261484375

terry fyy57m265195.91.829.59876543211108.24.70.833.88310258nynnynnnn117.957

Ward davidyy57m22532105.71.6638.35825228631307.85.11.21.816016590yynyynnny67.44320625

ellis ryy58m2184081.91.631.99218751099.15.61.232.213016686yynyynnyn63.5418

Hind georgeyy58m21147105.81.6240.3139765281259.52.80.960.68215272yynyynnyy130.134

lee gyy58m210481001.7333.41240936881267.94.21.152.87315472nynynnnnn138.1643835616

parkin sjyy58m21642116.71.7737.249832423613512.66.50.975.98615481yynynnnyy136.8646744186

spence raymondyy58m1322676.51.6727.4301696009977.83.20.930.914213066yynynynyy54.3365492958

butler jamesyy59m2104978.61.7326.26215376391056.17.72.630.913570ynnynnnnnproteinuria

everitt geoffreyyy59m2124784.61.6730.33454049981197.65.11.173.927713492yynyynnnn30.4285126354

green eyy59m235684.41.6630.62853824941116.33.91.311.616513070yynyynnny50.9622545455

khan lalmaryy59m295099.61.7333.2787597314124114.40.962.38313269yynyynnyy119.556

scarlett ayy59m2134690.71.731.3840830451066.940.770.611516386yynynnnnn78.5777478261

shaibi salehyy59m2554821.6729.402273297710974.70.850.97316397yynyynnnn111.9131506849

singh gucharanyy59m2164373.21.6626.5640876761067.83.51.071.710312268yynyynnnn70.8050097087

stansall royyy59m21445110.11.7535.95102040821318.25.61.52.19717070ynnynnnyn113.085185567

aldridge paulnn60m1174380.21.7227.1092482423946.64.82.130.410912140nynnnnnyn72.400733945

burkinshaw pyy60m245694.81.6236.12254229541145.64.61.131.68316880yynyynnny112.3893975904

eckhardt ayy60m2114992.41.7530.17142857141076.95.11.32.19610060yynyyyyny94.71proteinuria

ellis tonyyy60m215981.91.7227.6838831801103105.916.28916395yynynynnn90.5501123596

tyrell dyy60m22581231.9532.34714003941199.53.60.851.912214675ynnynnnyy99.206557377

ali maqsoodyy61m2154686.51.7727.61020141081088.83.50.751.911014275yynyynynana76.4109545455

brown dyy61m2160104.51.7832.98194672391286.43.71.361.25915678yynynnnyy172.1061864407

ellis malcolmyy61m2952152.31.847.00617283951506.43.50.95311314580yynyynnyy130.9645221239proteinuria

watson neilny61m2115082.21.8224.81584349721014.63.91.061.36512685nynnnnnny122.8826769231

bingham peteryy62m21745102.91.8231.06508875741196.14.61.081.57915080ynnynnnyy124.9648860759

chilton alanyy62m2134976.31.7225.79096809091076.841.010.96214080yynyynnyn118.0680967742

forrest davidnn62m1154787.31.7229.5091941591028.43.920.810112768nynnnnnnn82.9263564356

Hayes Philipyy62m28541051.7534.28571428571177.66.10.984.110415460ynnyynnnn96.8625

pendall brianyy62m23329117.21.7936.57813426551228.13.41.350.89611573yynynnnyy117.12675

pymm payy62m245879.71.727.57785467131037.74.71.123.511217391yynynnnyy68.2715892857microalbuminuria

saunders terenceyy62m2204265.81.7820.7675798519410.151.1226513070nynnnnnny97.1208

Wallis rogeryy62m21547127.41.8537.22425127831456.64.40.972.49415769yynyynyny130.0293191489

hurditch johnyy63m2144995.41.8129.11999023231167.440.925.712817281ynnyynnnn70.588546875

whittaker brianyy63m2125199.91.8828.26505205981258.53.70.981.86317494yynynynnn150.183

hall apyy64m22143106.71.832.93209876541289.74.40.821.811212062nnynnnnny89.0563928571

horne dyy64m22539801.727.68166089971049.23.81.1137118390ynnynnnyy105.3295774648

wigley gyy64m2361107.91.8132.93550257931067.63.60.861.611510874yynyynnny87.708626087

din zakavathnn65m2135266.91.6424.87358715051046.54.71.320.78512857nynnnnnyy72.6061764706

lancaster grahamyy66m275974.71.5929.54788180851057.35.10.921.713311274ynyynynnn51.1217593985

wood kyy66m2125493.91.7530.66122448981088.44.50.763.59012972nnnnynnyy94.9642

edis royyy67m166183.81.7627.053202479310610.14.31.451.96411870nnnnnnnny117.56878125

nortcliff williamyy67m2364105.31.8530.76698319941357.45.11.061.97813386yynyyynny121.2165

Allsebrook godfreyyy68m2194995.51.6136.84271440151295.22.92.190810060yynynynyy9.3144052863

frost byy68m2244493.51.7331.240602759911410.64.10.822.813722586yynyynnyy60.4405839416

ullah ayy68m216779.51.6329.92208965341097.42.90.521.411815981yynyynnny59.6654237288proteinuria

bramley dyy69m22049102.51.735.46712802771187.931.090.918114963yynyynyyn49.4548342541

cox alanyy69m21851109.31.737.82006920421209.77.20.8517.113014080yyyyynnnn73.4243769231

campbell asheryy70m276385.11.5535.42143600421106.74.21.451.79814378yynynynnn74.7664285714

gauntley byy70m21852100.11.7632.31534090911148.23.91.212.18915971yynynnnyn96.8383146067

moody jyy70m2195178.11.7226.39940508381009.92.91.172.38214060yynynnyyn82.005

ayres dyy71m2215070.91.6526.04224058771048.12.20.661.47414874nynynnnnn81.3146351351

grey burniceyy71m2304198.91.5541.16545265351196.34.60.961.310114786yynynnnnn83.1053762376

khaliq abdulyy71m2195274.61.6627.07214399771099.951.17212112759nynnynnyn52.3248099174proteinuria

majid naziryy71m2145762.11.4828.35098612131068.63.41.181.66713570ynnyynnyy78.6630895522

margerrison raymondyy71m2106191.71.7230.99648458631146.34.11.331.17516877ynnynnnnn103.76772

thabet syy71m2185366.71.6225.41533302859913.35.70.763.68616271yynynnnnn65.8235930233

bough byy72m21755106.11.8232.031155657511783.51.022.215014578yynynynyy59.16136

Fazal Kalsoumyy72m2195394.31.6235.932022557512893.10.734.19111460yynynynyy86.6730989011pakistani

ladva syn72m2135958.21.6122.45283746779012.13.90.80.86616879nnnynnnnn73.7552727273

lamb dyy72m21656111.71.9429.67903071531207.62.40.830.513115475yynynnnyy71.3174656489

marshall elsieyy72m2171115.61.645.156251305.94.51.441.98117074ynnynnnnn119.3677037037

Smithson harryyy72m287.61.7229.61060032451205.84.71.416116070