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Page 1: CIHRT Exhibit P-1726 Page 1cihrt.nl.ca/exhibits/June 23 Pritzker Exhibits/P... · Dr. K.P.H. Pritzker 1. POST GRADUATE EDUCATION 2. Rotating Internship.New Mount Sinai Hospital, Toronto

CIHRT Exhibit P-1726 Page 1

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Dr. K.P.H. Pritzker POST GRADUATE EDUCATION 1. 2. Rotating Internship. New Mount Sinai Hospital, Toronto - 1967-68

Assistant Resident, Medicine. New Mount Sinai Hospital, Toronto (Dr. B. Berris) (July 1, 1968 - June 30, 1969) This included three months experience in Clinical Oncology at the Princess Margaret Hospital, Toronto. 3. Pathology Training Program, McGill University (1969 - 72). i) Resident, Pathology, Pathology Institute and Royal Victoria Hospital.

(July 1, 1969 - June 30, 1970) (Dr. R.H. More) Resident, Pathology, Montreal General Hospital (July 1, 1970 - December 30, 1970) (Dr. W.H. Mathews). Resident, Pathology, St. Mary’s Hospital, Montreal (January 1, 1971 - June 30, 1971) (Dr. D.S. Kahn) Chief Resident, Pathology, Montreal General Hospital (July 1, 1971 - June 30, 1972) (Dr. W.P. Duguid)

ii)

iii)

iv)

This training program involved broad experience with surgical autopsy and cytological aspects of Pathology, as well as more limited exposure to Neuropathology, Pediatric Pathology and techniques of electron microscopy. As well, it involved considerable experience teaching Pathology at the under-graduate and resident levels.

LICENSES AND QUALIFICATIONS 1. 2. 3. 4.

Medical Council of Canada (L.M.C.C.C.) College of Physicians and Surgeons of Ontario License 21597 Royal College of Physicians and Surgeons of Canada (F.R.C.P.C) Anatomical Pathology College of American Pathologists - Fellow (FCAP)

1968

1968

1972

1987

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Dr. K.P.H. Pritzker Hospital Appointments 1. Mount Sinai Hospital: Director, Department of Pathology

and Laboratory Medicine Director, Departments of Pathology and Clinical Biochemistry Pathologist-in-Chief Head, Connective Tissue Research Group Staff Pathologist 2. Baycrest Centre for Geriatric Care, Toronto Medical Director, Laboratory Services Baycrest Medical Advisory Council Staff Pathologist 3. Toronto General Hospital Pathologist, Associate Staff 4. Princess Margaret Hospital Consultant 5. North York General Hospital Consultant, Dept. of Clinical Genetics

1994 - 1993-1994 1986 - 1979 - 1972 - 1995- 1995- 1972-1984 1983-1985 1988- 1999-

University of Toronto Appointments 1. Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto Professor* 2. Department of Pathology, Faculty of Medicine, University of Toronto

Associate Lecturer Assistant Professor Associate Professor* Professor*

*Faculty of Medicine and School of Graduate Studies.

1997- 1972-1973 1973-1976 1976-1980 1980-1985 1985-

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Dr. K.P.H. Pritzker 3. Department of Surgery, University of Toronto

Professor 4. Department of Clinical Biochemistry, University of Toronto Professor

University Teaching Responsibilities Participation in:- Undergraduate Medicine, Years II, III, IV Postgraduate Programs: Pathology, Rheumatology, Orthopedic Surgery, General Surgery Rehabilitation Medicine Graduate Programs: Pathology Bone/Mineral Group Centre for Biomaterials Course Director: PAT1016 Pathology of Connective Tissues (School of Graduate Studies)

Faculty of Medicine Pathobiology of Disease: Degeneration in the Articular Skeletal System 1990-2000

1988- 1994-1997

Appointments: Other Universities 1. Collaborating Scientist, Caribbean Primate Research Centre University of Puerto Rico 1988-1999

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Dr. K.P.H. Pritzker Principal Research Interests

Biomineralization: Normal and Pathological Pathogenesis of Degenerative Joint Diseases Pathogenesis of Crystal Deposits in Tissues Connective Tissues as Biomaterials Novel Biomaterials Biomedical Applications of Fullerenes Connective Tissue Neoplasia

Principal Development Interests Laboratory Organization and Direction Biomedical Research Services Translational Research Facilitation Provision of Clinical and Laboratory Genetics Services Bionanotechnology

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Dr. K.P.H. Pritzker LOCAL COMMITTEES MOUNT SINAI HOSPITAL Instructional Media Committee Chairman Library Committee Education Committee Research Advisory Committee Department of Laboratories Review Committee

Biosafety Committee Medical Advisory Council Vice-Chairman

Chairman Planning Advisory Committee

Chairman Medical Records and Communications

Committee - Chairman Budget Committee Credentials Committee

Chairman Joint Conference Committee Board of Directors 1989-1991 Computer Advisory Committee Constitution Committee, Chairman1991-2000 Mount Sinai Hospital Health Report, Advisory Board Gastro-Intestinal Program Planning Musculoskeletal Program Planning 1992-1998 Member, Search Committees (various medical, scientific administration) Perinatal Planning Council Surgical & Perioperative Planning Council Medical Planning Council Academic Community Health Planning Council Order Entry/Results Reporting Task Force Informatics Executive Committee Year 2000 Steering Committee Medical Research Council Executive Management Committee Operations Committee

1973-1986 1975-1980 1974-1980 1975-1980 1978-1983 1981-1982 1981-1983 1986- 1988-1989 1989-1991 1986-1995 1988-1989 1986-1989 1988-1997 1988-1991 1988-1989 1988-2006 1989-1991 1990-1992 1992-1997 1992-1996 1993- 1995-2002 1995-2002 1995-2002 1995-1997 1997 1998-2002 1998-2000 1998-2002 2000- 2000-

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Dr. K.P.H. Pritzker LOCAL COMMITTEES: MOUNT SINAI HOSPITAL continued Peter A. Silverman Centre for International Health, Mount Sinai Hospital/University of Toronto

Executive Committee 2001-2007 Associate Director 2001-2007 Chair, Advisory Committee 2007-

Chinese Advisory Committee 2001-2005 Research Committee 2003- Centres of Excellence 2006

Organizational Excellence Implementation Team Strategic Implementation Team 2006- Co-Chair, Laboratory Medicine and Infection Control, 2006-

Centre of Excellence Senior Leadership Team, Building on the Best: Implementing 2006-

Centres of Excellence MOUNT SINAI SERVICES 2006-

Founder

SAMUEL LUNENFELD RESEARCH INSTITUTE Principal Investigator Member, Research Advisory Committee Working Group on Technology Transfer/

Industrial Liaison Research Council Associate Scientist

FACULTY OF ENGINEERING, UNIVERSITY OF TORONTO Institute of Biomaterials and Biomedical Engineering (IBBME) Executive Committee, formerly known as Centre for Biomaterials Biomaterial Area Programme Planning Committee, Ontario Centre for Materials Research Advisory Board, Dept of Metallurgy and Materials Science Advanced Materials Advisory Committee Graduate Curriculum Committee (IBBME) Advisory Board, Dept. of Materials Science and Engineering, Vice-Chair Working Group on Bionanotechnology

1985-2000 1988-2000 1993- 1998-2001 2000- 1997- 1986-2000 1990-1994 1998-2000 1999- 2000- 2001- 2002-

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Dr. K.P.H. Pritzker FACULTY OF MEDICINE, UNIVERSITY OF TORONTO

Council Member Research Grants Committee " " " Chairman Task Force on Remuneration of Part Time, Staff Bone and Mineral Group, Executive Committee Various M.Sc. and Ph.D. Graduate Student Committees and Examination Committees Search Committees - various Strategic Planning Committee Decanal Promotions Committee Agenda Committee Member of Council, Clinical Sciences Sector Elected Representative, Faculty at Large, LMP Deputy Speaker, Faculty Council

FACULTY OF DENTISTRY, UNIVERSITY OF TORONTO Promotions Committee

1980-1986 1980-1986 1981-1986 1981 1985-1988 1980- 1986- 2000 2002-2005 2004- 2004-2007 2006- 2008- 1992-1998

DEPARTMENT OF PATHOLOGY, FACULTY OF MEDICINE, UNIVERSITY OF TORONTO

Committee on General Pathology 1973-1975 Committee on Musculoskeletal Teaching 1975-1989 Promotions Committee 1976-1979 Awards Committee 1977-1978 Examination Committee 1977-1983 " " Chairman 1981-1983 Coordinator, Musculoskeletal Teaching 1979-1987 Chairman, Remuneration Committee 1982-1987 Executive Committee 1983-1997 Undergraduate Education Curriculum Committee 1985-1987 Chairman, Long Range Planning Committee 1986-1994 J.B. Walter Pathology Teaching Award Committee 1991-1992 Chairman, Distinguished Pathologist Award Committee 1992

Budget Committee 1992-1996

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Dr. K.P.H. Pritzker DEPARTMENT OF LABORATORY MEDICINE AND PATHOBIOLOGY, UNIVERSITY OF TORONTO

Executive Committee 1997- Pathologists-in-Chief Committee 1997- MICHENER INSTITUTE OF APPLIED HEALTH SCIENCES Formerly Toronto Institute of Medical Technology Chairman, Histology Extension Courses

Advisory Committee Committee Member Executive Committee of the Advisory Council Medical Laboratory Technology Vice-Chairman Chairman Board of Governors (ex-officio) Program Director, Clinical Teaching Mount Sinai Hospital Program Advisory Council

ACADEMY OF MEDICINE, TORONTO Membership Committee Nominating Committee Secretary, Section of Pathology Chairman, Section of Pathology Council Member

1974-1977 1977-1978 1978- 1979-1980 1980-1981 1980-1981 1986- 1994 2005- 1975-1978

1976,1978,1985,1986 1977-1978 1978-1979 1977-1979 TORONTO ASSOCIATION OF TEACHING HOSPITAL LABORATORY PHYSICIANS

Chairman 1983-1986 TORONTO COORDINATING COMMITTEE ON REGIONAL GENETIC SERVICES

Member 1991

WOMEN’S COLLEGE HOSPITAL, OSTEOPOROSIS ADVISORY PANEL Member 1993-2000

YORKBIOTECH INC. Drug Development Consortium Planning Committee 2008-

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Dr. K.P.H. Pritzker PROVINCIAL COMMITTEES: ONTARIO MEDICAL ASSOCIATION - SECTION ON LABORATORY MEDICINE

Representative to Laboratory Medicine Manpower Working Party of the Post-Graduate Manpower Conference of Faculties of Medicine (Ontario) Committee 1977 Chairman, ad hoc Committee on Manpower 1979 Nominating Committee 1980-1982, 1995 Tariff Committee 1982-89, 1993-97 Chairman, Professional Practise Committee 1986-1989 Council Member 1989-1996 Secretary 1991-1992 Vice Chairman 1992-1993 Chairman 1993-1994 Past Chairman 1994-1995 Management Committee, Quality Management Program, Laboratory Services (formerly known as the Laboratory Proficiency Testing Program) 1993-2001 MOH/OAML Administration and Policy Review Committee, OMA Representative 1996 QMPLS-Health Canada Genetic Information System Pilot 2002-2004 Operating Strategy, Management Group

ONTARIO ASSOCIATION OF PATHOLOGISTS Nominating Committee 1979, 1981, 1982,

1983, 1984, 1986, 1987, 1996

1999- 2002- ONTARIO HOSPITAL ASSOCIATION Laboratory Services Advisory Committee Member, Ontario Working Group OHA, OMA, MOHLTC Laboratory Physician Human Resources

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Dr. K.P.H. Pritzker ONTARIO MINISTRY OF HEALTH

Toronto Central Group, Laboratory Restructuring Facilitation Process Ontario Provincial Advisory Committee on New Genetic Predictive Technologies

Laboratory Services Subcommittee Implementation Committee on Predictive Cancer Genetics Testing Funding Sub-Committee Transportation Sub-Committee (Chair)

Ontario Advisory Committee on Genetics Newborn Screening Subcommittee

1998-1999 2000-2001 2000-2001 2000-2003 2000-2003 2000-2003 2005-2007 2005-

ONTARIO CANCER TREATMENT AND RESEARCH FOUNDATION Ontario Medical Association Representative Working Party on Funding of CEA and Steroid Receptor Assays 1990-1997 Clinical Biochemistry Committee 1994-1997

ONTARIO CENTRE FOR MATERIALS RESEARCH Biomaterials Program Principal Investigator

WORKPLACE SAFETY & INSURANCE APPEALS TRIBUNAL Appeals Tribunal Medical Assessor

COLLEGE OF MEDICAL LABORATORY TECHNOLOGISTS OF ONTARIO

Regulatory Committee

1988-1996 1994- 2001

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Dr. K.P.H. Pritzker NATIONAL COMMITTEES: CANADIAN ASSOCIATION OF PATHOLOGISTS

Past President President President-Elect Vice-President Secretary-Treasurer Assistant Secretary Committee on Continuing Education Committee on Manpower Committee on Economic Status Delegate, Canadian Medical Association Delegate to World Association of Societies of Pathology (WASP) Delegate, Intersociety Council of Laboratory Medicine of Canada Delegate, Intersociety Pathology Council (U.S.) Delegate, International Liaison Committee of Presidents Chairman, Professional Practice Liaison Committee Chairman, Budget & Finance Committee Chairman, Nominating Committee

Nominating Committee Member, Consortium on Future of Pathology in Canada Member, Steering Committee, Humanities, Pathology Section

CANADIAN SOCIETY OF CYTOLOGY Member, Nominating Committee NATIONAL RESEARCH COUNCIL OF CANADA INSTITUTE FOR MICROSTRUCTURAL SCIENCES

External Advisory Board

1984-1985 1983-1984 1982-1983 1981-1982 1976-1981 1973-1976 1974-1984 1974-1986 1974-1986 1976-1984 1976

1979-1986 1979-1985 1983

1984-1987 1984-1985 1985-1986 1986

1992-1995 2006

1986

2005-2011 INTERSOCIETY COUNCIL OF LABORATORY MEDICINE OF CANADA

Member 1979-86 President 1986-88

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Dr. K.P.H. Pritzker ROYAL COLLEGE OF PHYSICIANS AND SURGEONS OF CANADA Chairman, Laboratory Medicine Specialty Committee 1987-1990 CANADIAN REFERENCE CENTRE FOR CANCER PATHOLOGY Chairman, Board of Directors 1987-1996 Chair, Board of Directors 1996-

formerly Canadian Tumour Reference Centre Member, Soft Tissue Tumour Panel 1979- Chairman, Conjoint Committee for C.T.R.C. 1985

CANADIAN ARTHRITIS SOCIETY Medical and Scientific Committee Research Grants Panel Science Communications Committee Canadian Arthritis Network (Federal Network Centre of Excellence)

Principal Investigator Steering Committee, Preclinical Core Facilities Organizing Committee, International Conference on Preclinical Models of Osteoarthritis

INTERNATIONAL COMMITTEES: UNITED STATES AND CANADA ACADEMY OF PATHOLOGY formerly INTERNATIONAL ACADEMY OF PATHOLOGY (U.S.-Canada Division)

Members Committee 1979-1981 Membership Committee 1983-1986 Musculo-skeletal Pathology Abstract Committee 1987-1991 Council Member 1991-1994 Young Investigator Award Committee 1998-2000

INTERNATIONAL DEVELOPMENT Chair, Pacific Bridge Project President, Pacific Bridge Foundation (Hong Kong) Sino-Judaic Institute, Member InterHealth Canada Limited Member, Special Projects Group Life Member, Hong Kong Museum of Medical Sciences

1992-2004 1996-2003 1996- 1996-1997 1996-

1980-1985 1994-2002 1999- 2001- 2006

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Dr. K.P.H. Pritzker WORLD CONGRESS ON BIOMATERIALS 1996 Steering Committee OSTEOARTHRITIS RESEARCH SOCIETY INTERNATIONAL Co-Chair, Working Group on Osteoarthritis Pathology OSTEOARTHRITIS INITIATIVES (NIH, FDA, OARSI) Workshop Participant, Washington D.C., February 28-29 World Association of Pathology and Laboratory Medicine, Cologne, Germany, November 19-23, 2001 INTERNATIONAL CARTILAGE REPAIR SOCIETY Member, Histologic Endpoint Committee

1990

1998-2006 2000

2001

2002- HONOURS: Government of Canada: Queen’s Silver Jubilee Medal 1977 Japanese Society for the Promotion of Science, Invitation Fellowship 1995 University of Toronto, Department of Laboratory Medicine and 2000

Pathobiology, Distinguished Service Award Canadian Association of Pathologists, 2001 CAP Distinguished Service 2001

Award Karen McGibbon Awards of Excellence 2005

Seymour Schulich Honorariums Mount Sinai Hospital Network of Knowledge Team affiliated with the Peter A. Silverman Centre for International Health

Special Community Presentation: 2006 th Holy Blossom Temple, 150 Anniversary Program,

Edmund Scheuer Presentation, Toronto, Ontario, November 12, 2006

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Dr. K.P.H. Pritzker PROFESSIONAL SOCIETIES: LOCAL Academy of Medicine, Toronto Clinical Research Society of Toronto Toronto Calcium and Bone Club University of Toronto Medical Alumni Society PROVINCIAL Ontario Association of Pathologists Ontario Medical Association NATIONAL Royal College of Physicians and Surgeons of Canada Canadian Association of Pathologists Canadian Biomaterials Society Canadian Society of Cytology Microscopical Society of Canada Canadian Medical Association Canadian Rheumatism Association Canadian NanoBusiness Alliance UNITED STATES Alpha Omega Alpha Honour Medical Fraternity American Society for Bone and Mineral Research American Society of Clinical Pathologists Arthur Purdy Stout Society of Surgical Pathologists The Binford-Dammin Society of Infectious Disease Pathologists College of American Pathologists 1987 - Fellow (FCAP)

Connective Tissue Oncology Society

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Dr. K.P.H. Pritzker INTERNATIONAL International Skeletal Society Osteoarthritis Research Society International Paleopathology Club United States and Canada Academy of Pathology formerly the International Academy of Pathology (U.S.-Canada Division)

International Society for Telepathology, Member European Association for the History of Medicine and Health European Committee on Telepathology, Member Sino-Judaic Institute Hong Kong Museum of Medical Sciences (Life Member) Materials Research Sociey

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Dr. K.P.H. Pritzker MISCELLANEOUS SCHOLARLY JOURNALS

Editorial Board Member Journal of Rheumatology Modern Pathology (USCAP) Pathology Research and Practice,

North and South American Editorial Board North American Regional Editor Executive Editor

European Journal of Experimental Musculoskeletal Research Osteoarthritis and Cartilage 2001 Yearbook of Science & Technology

Consulting Editor McGraw-Hill Encyclopedia of Science and Technology Consulting Editor

Mount Sinai Hospital Foundation Online Health Newsletter Current Rheumatology Reviews The Open Rheumatology Journal

1980- 1992-1995 1992- 1996-1997 1997- 1991-1996 1994-2004 1999- 2001- 2004- 2005- 2007- Reviewer Acta Orthopedica Scandinavicha American Journal of Pathology American Journal of Physical Anthropology Anatomical Record Archives of Oral Biology Archives of Pathology and Laboratory Medicine Arthritis and Rheumatism Biochemistry and Cell Biology Bone and Mineral Cancer Letters Cancer Research Cardiovascular Pathology Connective Tissue Research Crystal Growth and Design Experimental and Molecular Pathology European Journal of Biochemistry Human Gene Therapy Human Pathology IN VITRO Journal of Archaelogical Science

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Dr. K.P.H. Pritzker Reviewer continued Journal of Bone and Joint Surgery Journal of Bone and Mineral Research Journal of Crystal Growth Journal of Microbiology Journal of Otolaryngology (The) Journal of Physical Chemistry Journal of Rheumatology Medical Science Monitor Metabolism, Clinical and Experimental Osteoarthritis and Cartilage Pathology, Research and Practice Scanning Electron Microscopy The Journal of Physical Chemistry Thermochimica Acta

Grant Reviewer Ontario Cancer Treatment and Research Foundation Canadian Arthritis Society Medical Research Council of Canada National Cancer Institute Kroc Foundation Science & Engineering Research Council (Great Britain) Veteran’s Administration, U.S. National Institutes of Health B.C. Health Care Research Foundation Alberta Heritage Foundation for Medical Research Basic Research Foundation, Israel Academy of Sciences and Humanities Sandoz Foundation for Gerontological Research United States-Israel Binational Science Foundation Canadian Blood Services NSERC Material Sciences and Engineering Research Committee Canadian Institutes of Health Research Chinese University of Hong Kong Grants Committee National Medical Research Council, Singapore

1975 1978- 1979-2000 1980- 1981-1982 1983- 1984- 1984- 1986- 1990- 1991- 1995- 1999- 1999- 2000- 2000- 2004- 2006-

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Dr. K.P.H. Pritzker LOCAL ARRANGEMENT COMMITTEES:

American Association of Pathologists/International Academy of Pathology Meeting, Toronto, March 1977 Symposium on Crystal Deposits in Human Disease Toronto, Canada, August 13-14, 1981. Arthur Purdy Stout Society of Surgical Pathologists, Toronto, March 1985. International Academy of Pathology, Toronto, March 1985. Chair, Organizing Committee, Canadian Congress of Laboratory Medicine, Toronto, June 1992. Co-Chair, Organizing Committee, Canadian Connective Tissue Conference, Toronto, June 1996. Ontario Pathologists’ Assistants 1 st Update Meeting, Mount Sinai Hospital, Toronto, November 18, 2006. Opening remarks: Pathology Assistants I Ontario and it New Organization Canadian Association of Pathologists, 58 th Annual Meeting, Toronto, 2007.

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Dr. K.P.H. Pritzker CONSULTANT 1. Working Party of the Canadian Association of Pathologists to the Task Force of the

Requirements Committee on Physical Manpower (Federal Government) 1974-76 Thorne Stevenson Kellogg - Operational Review, Department of Laboratories, University of Alberta Hospital, Edmonton, Alberta, 1985. Ciba-Geigy Inc: (U.S.) Pharmaceutical Division, May 12-13, 1987. Med-Chem Laboratories Limited, 1975 - 1999. Canadian Medical Protective Association (Medico-Legal), 1986 - British Columbia Cancer Control Agency - Operational Review, Department of Pathology, June 26-28, 1991. St. Paul’s Hospital, Vancouver, British Columbia - Operational Review, Department of Pathology, April 8-10, 1992. William Beaumont Hospital, Royal Oak, Michigan - College of American Pathologists Accreditation Inspection, February 25, 1994 Spectral Diagnostics Inc. Member, Scientific Advisory Board, 1996 - 1997

Chiron Inc., Osteoarthritis Program, August 1996 - 2000

Working Ventures Canadian Fund Inc., May 1997 Global Research Network International (GRN), 1997- Millenium Biologics, 1998 B12 Inc., 1999 - C60 Inc., 1999 - Avantec (formerly LEAP Medical), 2000- Viventia Biotech, 2000-

2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17.

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Dr. K.P.H. Pritzker CONSULTANT continued 18. Aurillion Micro Systems, 2005- EXHIBITS SYNOVIAL FLUID ANALYSIS M.L. Russell and K.P.H. Pritzker American College of Physicians Post-graduate Course - Rheumatology, Toronto, 1976 ROUND TABLE MODERATOR ANALYSIS OF JOINT FLUIDS American Society of Cytology 25th Annual Meeting, Toronto, November 3, 1977 MODERATOR DEGENERATIVE ARTHRITIS: RECENT ADVANCES IN PATHOPHYSIOLOGY AND DIAGNOSIS Academy of Medicine/Toronto Pathology Circle, Monday, September 21, 1987 ARTHRITIS International Skeletal Society, San Diego, CA, September 26, 1991 BONE CHANGES IN NON-HODGKIN LYMPHOMA The International Skeletal Society, Toronto, Ontario, August 17, 1993 ISSUES INVOLVED IN LINKING BIOCHEMISTRY AND ULTRASOUND Canadian Symposium on Prenatal Screening, Toronto, Ontario, June 4, 2004

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Dr. K.P.H. Pritzker INVITED PANELIST 1. National Institute of Health (Arthritis Metabolism and Digestive Diseases)/ American Academy of

Orthopedics, Workshop on low back pain, Miami, Florida, December 8-10, 1980. 2. Dahlem Conference "Biological Mineralization", Berlin, Germany, October 18-23, 1981. 3. Comparative Pathology Panel, International Academy of Pathology, Boston, Mass., U.S.A. March 3, 1982. 4. Workshop on Clinical Patterns and Pathologic Features in Osteoarthritis, Kingston, Ontario, Canada, August 13-15, 1982. 5. Gordon Conference on Calcium Phosphates, Plymouth, New Hampshire, June 27 - July 1, 1983. 6. National Institutes of Health, (Arthritis, Metabolism and Digestive Diseases) American Academy of Orthopedic Surgery, Workshop on Osteoarthritis, Warrenton, Virginia, USA, July 21-25, 1985. 7. Conference on Crystal deposition and dissolution in tissues, Lugrin, France, September 26-28, 1985. 8. National Institutes of Health (Arthritis, Metabolism and Digestive Diseases) Workshop on "Infectious Etiology of Early Arthritis", Bethesda, Maryland, USA, November 20-21, 1985. 9. Canadian Sarcoma Group, Terry Fox Workshop, Molecular Biology of Sarcomas, Idlewyld Inn, London, Ontario, December 9-11, 1990 (Organizing Committee).

10. The International Skeletal Society, 14th Annual Refresher Course "Imaging of articular cartilage: Where do we go from here?", Santa Fe, New Mexico, September 10-13, 1997. 11. Mount Sinai Hospital Business Development Committee, Pathology and Laboratory

Medicine Business Strategy Presentation, Toronto, Ontario, January 23, 2003. 12. Canadian Genetics Diseases Network Retreat, "The Evolution of CGDN", Toronto, Ontario,

February 2-3, 2003. 13. Centre for Health Economics and Policy Analysis Roundtable on Policy Issues for New and

Emerging Genetic Services, Sunnybrook Estates, Toronto, Ontario, February 17, 2003.

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Dr. K.P.H. Pritzker INVITED PANELIST continued 14. National Institute of Arthritis and Musculoskeletal and Skin Diseases: Opportunities for Translational

Research on Articular Crystal Deposition Diseases: Gout, CPPD Crystal Deposition Disease, Hydroxyapatite Deposition Arthropathy: A Round Table Discussion, Washington, DC, April 23, 2003.

SITE REVIEWER National Institutes of Health Review: Arthritis Group, Daniel J. McCarty, University of Wisconsin, Milwaukee, Wisconsin, USA. December 10-12, 1986. Bion Science Review for the USRA/NASA/CNES/RSA Program, NASA Ames Research Center, California, December 4-6, 1995. ACADEMIC VISITOR 1. 2. 3. 4. 5. 6. 7. 8. 9. 10.

Department of Pathology, University of Alberta, Edmonton, March 27-29, 1980. Department of Pathology, University of Calgary, Calgary, January 8-10, 1981. Department of Medicine, Universidad de Santiago, Santiago, Chile, April 26-30, 1982. Department of Pathology, Queen’s University, August 15, 1982. Department of Pathology, McGill University, May 9-10, 1983. Faculty of Medicine, University of Puerto Rico, San Juan, Puerto Rico January 31 - February 3, 1984. Department of Pathology, University of Manitoba, December 12-14, 1984. Medical Research Council of Canada Visiting Professor, Departments of Pathology, Medicine and Radiology, University of Western Ontario, London, Ontario, May 22-24, 1985. Departments of Biochemistry and Pathology, Rush Medical School, Chicago, Illinois, USA, September 3-4, 1985. Department of Medicine, Bristol University, Bristol, England, September 24, 1985.

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Dr. K.P.H. Pritzker ACADEMIC VISITOR continued 11. 12. 13. 14. 15. 16. 17. 18.

Department of Pathology, University of Alberta, Edmonton, Alberta, January 8-11, Department of Pathology, University of British Columbia, March 3-4, 1986. Department of Biochemistry, Rush Presbyterian St. Lukes Medical Centre, March 10-11, 1987. Department of Pathology, McMaster University, Hamilton, Ontario, May 29, 1987. Department of Pathology, Hadassah Hospital, Ein Karem, Jerusalem, Israel, March 19, 1989. Department of Structural Chemistry, Weizmann Institute of Science, Rehovot, Israel, March 26, 1989. Bone and Joint Research Unit, The Royal London Hospital Medical College, University of London, London, England, May 21, 1991. Departments of Medicine and Malcolm and Dorothy Coutts Research Institute, University of California, San Diego, La Jolla and San Diego, California, USA, September 24-25, 1991. Herchel Smith Laboratory of Medicinal Chemistry, Addenbrookes Hospital, Cambridge University, Cambridge, England, 14 May 1992. Department of Pathology, University of Hong Kong, 23 October 1992. Departments of Pathology, Beijing Medical University and Peking University Medical College, 26 October 1992. Department of Pathology, Nanjing Medical College and Jiangsu Province Hospital, 27-28 October, 1992. Department of Pathology, Chinese Medical University of Hong Kong, 30 October 1992. Department of Pathology, Zhejiang Medical University, 22 November 1993. Department of Pathology, Second Shanghai Medical University, 23 November 1993. National Yang Ming Medical University, Taipei, Taiwan (R.O.C.), October 20, 1994. Department of Pathology and Laboratory Medicine, University of Puerto Rico, February 28, 1995.

1986.

19. 20. 21. 22. 23. 24. 25. 26. 27.

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Dr. K.P.H. Pritzker ACADEMIC VISITOR continued 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45.

Department of Pathology, Kanazawa Medical University, Kanazawa, Japan, May 15, 1995. Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan, May 19, 1995. Department of Pathology, University of Tokyo, Tokyo, Japan, May 22, 1995. Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan, May 23, 1995. Department of Pathology, Tokyo Jikeikai University School of Medicine, Tokyo, Japan, May 26, 1995. Department of Pathology, Hokkaido University School of Medicine, Sapporo, Japan, May 29, 1995. Departments of Pathology and Orthopedic Surgery, Gunma University School of Medicine, Gunma, Japan, June 3-5, 1995. Sysmex Techno-Center (R & D), TOA Medical Electronics, Kobe, Japan, June 8, 1995. Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, May 7, 1996. Inflammation and Osteoarthritis Biology Research Group, Ciba-Geigy, Summit, N.J., June 4, 1996. Department of Pathology, Univerity of Hong Kong, October 31, 1996. Department of Pathology, Chinese Univeristy of Hong Kong, November 1, 1996. Institut f r Pathologie, Universit t Giessen, Giessen, Germany, June 19, 1998. Department of Orthopedic Surgery and Pathology, Gunma University, Maebashi, Japan, March 3-4, 1999. Department of Pathology, University of Tokyo, Japan, March 5, 1999. Institute of Tropical Medicine, Nagasaki University, Japan, March 8, 1999. Department of Pathology, Kyoto University, Japan, March 10, 1999. Department of Chemistry, Rice University, Houston, Texas, June 1, 2001.

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Dr. K.P.H. Pritzker ACADEMIC VISITOR continued 46. 47.

Department of Bioengineering, University of Washington, Seattle, Washington, October 15, 2001. World Association of Pathology and Laboratory Medicine, Cologne, Germany, November 18, 2001. TNO Prevention & Health Gabius Laboratory, Leiden, Netherlands, November 23, 2001. Department of Pathology, Berne, Switzerland, November 24, 2001. Department of Bioimmunology, M.D. Anderson Hospital, Houston, Texas, USA, January 2002. First McCaig International Symposium on Joint Injury and Repair, University of Calgary, Department of Orthopedic Surgery, March 21-24, 2002. Pfizer Research Laboratories, Groton, Connecticut, USA, July 24-25, 2002.

48. 49. 50. 51. 52. 53. Sysmex Central Research Laboratory, Kobe, Japan, September 4, 2002. 54. Vancouver Coastal Health Authority, Vancouver, BC, February 7, 2003. 55. Department of Pathology, University of Lausanne, Switzerland, May 19, 2003. 56. Department of Pathology, University of Bern, Switzerland, May 20, 2003. 57. Aventis Pharma, Frankfurt-Main, Germany, May 24, 2004. 58. National Institutes of Health Arthritis, Musculoskeletal and Skin Diseases, Washington DC,

June 23, 2004. 59. Department of Human Pathology, University of Tokyo, Tokyo, Japan, September 21, 2005. 60. Japanese Foundation for Cancer Research, Tokyo, Japan, September 21, 2005.

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Dr. K.P.H. Pritzker SHORT COURSE CO-DIRECTOR 1. Metabolic and Degenerative Processes of Bone and Cartilage. International Academy of Pathology,

March 4, 1982, March 16, 1985 and March 10, 1987, March 9, 1989. An Approach to Bone Pathology, Canadian Association of Pathologists, June 1986, 1987, 1988. Practical course on synovial fluid analysis and crystal identification. XVIIIth ILAR Congress of Rheumatology, Barcelona, Spain, July 4-9, 1993. Metabolic bone disease Parts I and II. International Skeletal Society, Singapore, September 28- October 1, 2005.

2. 3. 4. SESSION CHAIRMAN 1. 2. 3.

Experimental Pathology - Canadian Congress of Laboratory Medicine, Montreal, Quebec, 1983. Bone and Soft Tissue Pathology, Canadian Congress of Laboratory Medicine, June 25, 1985. Session B: "Occurrences of biominerals". Conference on: Crystal deposition and dissolution in tissues, Lugrin, France, September 26-28, 1985. Mid west Connective Tissues Conference, Chicago, Illinois, November 15, 1986. Developmental and Bone Pathology, Canadian Congress of Laboratory Medicine, Quebec City, June 16, 1987. Bone and Connective Tissue Pathology, Canadian Congress of Laboratory Medicine, Winnipeg, Manitoba, June 27, 1988. Proffered Papers Session, Canadian Congress of Laboratory Medicine, St. John’s, Newfoundland, June 25, 1990. Proffered Papers Session, "Bone and Soft Tissue", US/CAN Academy of Pathology, Chicago, Illinois, March 18, 1991. Session Co-Chair, "Osteoarthritis and bone pathology of nonhuman and human primates". American Society of Primatologists, Glendon College of York University, Toronto, Ontario, June 19, 1992.

4. 5. 6. 7. 8. 9.

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Dr. K.P.H. Pritzker SESSION CHAIRMAN continued 10. 11. 12. 13.

Scientific Chairman, Ontario Association of Pathologists, Kingston, Ontario, Sept 30, Oct 1-2, 1993. Pathologic Mineralization. Gordon Conference on Calcium Phosphates 1994. Chair, Symposium on Molecular Epidemiology of Cancer. The XX International Congress of the International Academy of Pathology Meeting, Hong Kong, October 11, 1994. Chair, Symposium on Advances in the Molecular Biology of Some Tumours. The 3rd Joint Meeting of International Academy of Pathology (IAP), Chinese Division and Chinese Society of Pathology, CMA. Guangzhou, China, October 16, 1994. Session Chair and Co-organizer. The Arthritis Day, University of Toronto, January 26, 1995. Chair, Symposium on Bone and Soft Tissue Disease. The 4th Congress of Asia Pacific Association of Societies of Pathology, Beijing, China, May 9, 1995. Session moderator. Osteomyelitis, International Skeletal Society, New Orleans, Louisiana, October 17, 1995.

14. 15. 16. 17. Moderator. Diagnostic Services. Discussion leader, Division of Oncologic Pathology Retreat,

Princess Margaret Hospital, Toronto, October 17, 1996. 18. Session Chair "Intravascular Engorgement and the Pathogenesis of Osteoarthritis". Osteoarthritis

Research Society, Singapore, June 8, 1997 19. Plenary Session Chair, The Joint Conference of International Academy of Pathology Chinese

Division and Chinese Society of Pathology, Shanghai, China, October 31, 1997. 20. Co-Chair. OARSI Working Group on Osteoarthritis Histopathology, Florence, Italy, October 16,

1998

21. Session Chair, Consensus Conference on Osteoarthritis, Toronto, Canada, April 21, 2002 22. Session Chair, "Issues involved in linking biochemistry and ultrasound", 2004 Canadian Symposium on Prenatal Screening, June 4, 2004 23. Session Chair on Arthritis, International Cartilage Repair Society, Toronto, Canada, June 15-18,

2002

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Dr. K.P.H. Pritzker SESSION CHAIRMAN continued 24. Session Moderator: Cartilage I, 5 th Combined Meeting Orthopaedic Research Societies of Canada, USA, Japan and Europe, Banff, Alberta, Canada, October 10-13, 2004 25. Session Chair, Natural Occuring Models, CAN, International Conference on Preclinical Models of

Osteoarthritis, Montreal, May 18-19, 2006 26. Session Co-Chair, Breakout Session 3, Analytical methods assessment of structural change

(cartilage, bone, menisci, ligaments, imaging), CAN, International Conference on Preclinical Models of Osteoarthritis, Montreal, May 18-19, 2006

27. Chair, Amgen Canada KRAS Biomarker Pathology Advisory Board Meeting, Toronto Hilton, Toronto, May 23, 2008

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Dr. K.P.H. Pritzker CONNECTIVE TISSUE RESEARCH GROUP Summer Students

Cathy E. Zahn Raymond Viola Margaret Podesta Augustus Leung Daniel Houpt Andrew Kanalec Jordan Herst Barbara Allen Stephen Gawron Sydney Feldman Kerri Palangio Vivienne Ang Francis Li John Kim Erika D’Agatta John Grabher Patricia Harason Don Kim Lynne Molinari Susan Reicheld Steve Tishler Shawn Bader Roberta Veitch Lydia Kim Sonali Patel Teresa Tran Nilupa Kamalina Srinivas Vithoori Robert Krempien Annette Miller Stacey Cheng

* 4 th year project student

1976 1978 1978 1979 1981 1981 1982,1983 1983,1984 1983 1984,1985 1984 1985 1985 1985 1986 1986,1987 1986,1987 1986 1986 1986 1986 1987 1987 1987 1987 1988 1988 1988 1988 1989 1989

Brian Trussler Michael Wong Riyana Babul Dan Nir Yan Lau Joseph Po Nick Sansalone Eilis Hamilton Nusrat Khan Ji-Young Lee Eli Mandel David Morrissey Andrew Pilliar Farid Visram Jaqueline Tsang Brendan C. Dickson Jordan J. Hesse Tanya Monga Syed Naweed Raza Grace So

Tanya Hauck Sonia Ng Jovil Kanampuza Vincent Lau Piotr Malinouski Fanny Provost Irene Liu

1989 1989 1989 1989 1990 1990 1990 1990 1993 1994-1996 1996-1998 1996-1999 1997 1997 1999 2000 2001 2001, 2002 2001 2002, 2003, 2004, 2005* 2006 2003, 2004* 2004, 2006*, 2007 2005*, 2006 2007*, 2008 2007 2007 2008

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Dr. K.P.H. Pritzker Research Fellows Jeffrey Berger, D.D.S. Mark E. Adams, M.D. 1977-1978

1977-1978 (part-time) Post Doc - K.M. Hunter Foundation Arthritis Society Research Fellow - Post Doc - M.Sc., 1980, Dept. of Pathology. - Medical Research Council of Canada, Research Fellow - Starr Medal, University of Toronto - Post Doc - Post Doc - Gerontology Research Council of Ontario Fellow - Post Doc - M.Sc., Starr Medal, University of - Medical Research Council of Canada, - Starr Medal, University of Toronto - Arthritis Soc. Fellowship - declined - M.Sc.

Ron Goldberg, M.D. Roland DiGregorio, B.Sc. Joanne Ch teauvert, B.Sc.

1984

1984-1986 1985-88 Fellowship

1985-1986 1986-1988

- Clinical Fellow - Post Doc - M.Sc., Edward Christie Stevens Fellowship - M.Sc. 1990. Edward Christie Stevens - University of Toronto Open Fellowship Ian Katz, M.D. Sushila Lucas, B.Sc.

- Robin Sullivan Memorial Prize - Fellow - M.Sc.

Richard C. Renlund, D.V.M. Rita A. Kandel, M.D. 1979-1980

1981-1982 Cleo Rogaku, M.D. Graeme K. Hunter, Ph.D. David Hogan, M.D., FRCPC Edward D. Simmons, M.D.

1981-1982 1983-1985 1983-1984 1983-1984 1985-1986 Toronto 1983-1984 Research Fellow

Brian Alpert, M.D. 1983-1985

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Dr. K.P.H. Pritzker Cameron Huckell, M.D. Sarah Keating, M.D., FRCPC 1986-1987

1987-1988 - Fellow - Graham Campbell Fellowship in Pathology and Bacteriology, University of Toronto - Ontario Ministry of Health Research Fellowship - M.Sc. - Fellow - Fellow - M.Sc. - Ph.D. - Ph.D. - Ontario Graduate Scholarship 1996 - M.Sc. - Medical Research Council Studentship - M.Sc. - Ph.D.

Isadore Lieberman, M.D. David Lyons, M.D., FRCPC Angela Acito, B.Eng. Yan Xu, M.D. Harpal Gahunia, B.Sc., M.Sc. Ph.D. Silvia Luca

1987-1988 1988-1990 1989-1991 1988-1993 1989-1999 1993-1997

Glenn Joiner 1997-1999 Ross Baker, M.Sc. 1999-2001 Jennifer Waddell, M.Sc. Riva Black Pauline So Las Heras, Facundo Kanampuza, Jovil

1999-2002 2003-2005 2003-2005 2004- 2006-

- M.Sc. - M.Sc. - M.Sc. - Ph.D. - M.Sc.

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Dr. K.P.H. Pritzker Post-Doctoral Fellows Tak Lam, Ph.D. Tetsuya Shinozaki, MD, DMSc Yu, Chi

1989-1990 1991-1993 2000-2003 VISITING SCIENTISTS Osman Sencer, M.Sc. August-October 1981 Head, Division of Electron Microscopy

Faculty of Medicine University of Ankara Ankara, Turkey. Department of Rheumatology University of Santiago Santiago, Chile. Department of Pathology West China University of Medical Sciences Chengdu, Sichuan Province People’s Republic of China Sandoz and Centre Universitaire de Moncton Ecole de nutrition et d’ tudes familiales Hoffman-LaRoche Co. Department of Pathology Carmel Hospital P.O.B. 7222 Haifa 34362, Israel Department of Pathology Yang-Pu District Tumor Hospital 335 Ping-Liang Road Shanghai, People’s Republic of China

Javier Basualdo, M.D. 1985 - 1986

Yao Xian Ying, M.D. 1988 - 1989

Pricille Mass , Ph.D. 1989 (6 months)

Irit Elmalah, M.D. Jan. 1990 - June 1991

Qiao Rui-Fang, M.D. Apr. 1990 - Sept. 1991

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Dr. K.P.H. Pritzker VISITING SCIENTISTS Huang, Xiaoyuan, M.D. Sept. 1990 -June 1992 Department of Pathology

Beijing Institute of Traumatology & Orthopaedics Beijing Ji Shui Tan Hospital Beijing 100035, Peoples Republic of China or 9 Gong Yu, No. 24, Qing Hua University Beijing 100084, People’s Republic of China Department of Pathology Shanghai Second Medical University 280 Sough ChongQiang Road Shanghai, 200025, People’s Republic of China Department of Oncology Affiliated Union Hospital FuJian Medical University FuZhou 350001, China Professor, Department of Pathology Shanghai Second Medical University 280 South Chongqing Road Shanghai 200025, China Director of Pathology Jiangsu Province Hospital (The First Affiliated Hospital of Nanjing Medical University) Nanjing 210029, China Chairman, Department of Oral Pathology College of Stomatology West China University of Medical Sciences Chengdu, Sichuan 710044, China RuiJin Hospital Shanghai Second Medical University 280 South Chongqing Road Shanghai, China

Yao, Shen M.D. Sept. 1992 - Feb. 1994

Cai, Jian-chun, M.D. March 1995 - July 1996

Wang, Rui-nian, M.D. July 1995-January 1996

Fan, Qin-he, M.D. February 96 -January 1997

Lu, Yong, M.D. November 97 - March 1999

Jiang, Cao-yang, M.D. December 97 - July 1999

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Dr. K.P.H. Pritzker VISITING SCIENTISTS Zhao, Yun, M.D. August 2000 - January 2001

Department of Obstetrics & Gynecology Beijing People’s Hospital/Beijing Medical University 11 Xi Zhi Men South Street Beijing, 100044, P.R. China Deputy Director, Hospital Administration Shanghai Second Medical University 280 South Chongqing Road Shanghai, China Deparment of Obstetrics & Gynecology Beijing People’s Hospital/Beijing Medical University 11 Xi Zhi Men South Street Beijing 100044 P.R. China

Wang, Ju-fang September - November 2001

Liang, Meiying August 2002 - March 2003

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 1. Pritzker KPH: Malignant tumours in transplant recipients.

i) 27i me Congr s: Association de M decins de Laboratoire du Qu bec, Montebello, Qu bec, June 17, 1971.*

ii) Canadian Association of Pathologists Annual Meeting, Saskatoon, Saskatchewan, June 21, 1971. Czitrom A, Gross A, Langer F, Pritzker KPH: Assessment of the cellular and humoral response to experimental bone allografts. Canadian Orthopedic Research Society, St. John’s, Newfoundland, June 23, 1974. Gross A, Luk SC, Langer F, Pritzker KPH: Allografted articular cartilage - a histopathological study. Canadian Orthopedic Research Society, St. John’s, Newfoundland, June 24, 1974.* Langer F, Czitrom A, Gross A, Pritzker KPH: Immunogenicity of bone allografts. Canadian Orthopedic Research Society, St. John’s, Newfoundland, June 24, 1974. Koven I, Pritzker KPH, Liswood A: The interstitial tissue barrier: a component of poor capillary flow. Royal College of Physicians and Surgeons of Canada,Winnipeg, Manitoba, January 24, 1975. Degenerative processes in the intervertebral discs. Refresher Course for Practising Pathologists, University of Toronto, Toronto, February 15, 1975.* Czitrom A, Langer F, Gross A, Luk SC, Pritzker KPH. Virus induced osteosarcoma in rats - an experimental model for the study of human osteosarcomas. Orthopedic Research Society (USA), San Francisco, California, March 1, 1975. Koven IH, Pritzker KPH, Lo S: The liver sinusoid barrier during low flow: Its Correction by Hyaluronidase. The 10th Congress of the European Society for Experimental Surgery, Paris, France, April 1975. Koven IH, Pritzker KPH, Liswood A, Lo S: Interstitial tissue barrier during low flow: Its Correction by Hyaluronidase. First World Congress for Microcirculation, Toronto, June 14, 1975. Urowitz EP, Czitrom A, Langer F, Gross A, Pritzker KPH: Immunogenicity of msv-m induced rat osteosarcoma. Canadian Orthopedic Research Society, Ottawa, Ontario, May 23, 1975. Czitrom A, Langer F, Gross A, Luk SC, Pritzker KPH: Virus induced experimental osteosarcoma - development of a model for human tumours. Societ Internationale de Chirurgie Orthop dique Traumatologie, XIII World Congress, Copenhagen, Denmark, July 1975.

2. 3. 4. 5. 6. 7. 8. 9. 10. 11.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 12. Houpt JB, Langer F, Gross A, Pritzker KPH: Allotransplantation of joint surfaces in the treatment of

osteonecrosis of the medial femoral condyle. American Rheumatism Association, New Orleans, Louisiana, June 5, 1975. Pritzker KPH: The pathogenesis of intervertebral disc degeneration. The Ontario Association of Pathologists, Toronto, October 3, 1975.* Pritzker KPH: Cellular events in intervertebral disc involution and degeneration. Interurban Arthritis Club, Toronto, October 18, 1975. Langer F, Gross A, Houpt JB, Pritzker KPH: Immunology of human cartilage transplants. Interurban Arthritis Club, Toronto, October 18, 1975. Pritzker KPH, Houpt JB: Pathology of spontaneous osteonecrosis of the knee. Annual Meeting of the Royal College of Physicians and Surgeons of Canada, Quebec City, January 23, 1976. West M, Langer F, Gross AE, Urowitz E, Pritzker KPH: In vitro studies in cell-mediated immunity in patients following allogenic joint transplantation. Canadian Orthopedic Research Society, Montreal, Quebec, March 13, 1976. Czitrom A, Langer F, Gross AE, Pritzker KPH, West M, Urowitz E: Immunotherapy of a virus-induced experimental osteosarcoma. Canadian Orthopedic Research Society, Montreal, Quebec, March 13, 1976. Pritzker KPH, Luk SC: Apatite associated arthropathies. Scanning Electron Microscopy 1976 Workshop on Techniques for Particulate Matter Studies in the S.E.M., Toronto, April 19, 1976.* Pritzker KPH: Cellular events in intervertebral disc degeneration. American Rheumatism Association, Chicago, Illinois, June 11, 1976.* Pritzker KPH: Aging and degeneration in the lumbar intervertebral discs: histological and histochemical studies. International Society for the Study of the Lumbar Spine. Southampton, Bermuda, June 23, 1976.* Pritzker KPH, Phillips H, Luk SC, Koven IH, Kiss A, Houpt JB: Pseudogout pseudotumor of the temporomandibular joint. Canadian Association of Pathologists, Halifax, Nova Scotia, June 29, 1976. Pritzker KPH: Pathophysiology of tissue injury in rheumatic diseases. American College of Physicians Post Graduate Course: Selected Topics in Rheumatology, Toronto, September 8, 1976.*

13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 24. Pritzker KPH, Langer F, Gordon AS, Starkman SP: Scapulo-peroneal dystrophy. Canadian Congress of

Neurological Sciences, Winnipeg, Manitoba, October 13, 1976. Pritzker KPH, Gross AE, Langer F, Luk SC, Houpt JB: Articular cartilage allotransplantation: histological studies. XI International Congress of the International Academy of Pathology, Washington, DC, October 20, 1976. Pritzker KPH: Osteoarthritis - pathology and pathogenesis. University of Toronto Postgraduate Course on the Arthritides for Physical Therapists, Toronto, October 23, 1976.* Pritzker KPH, Zahn CE, Nyburg SC, Luk SC, Houpt JB: Crystal ultrastructure and the pathogenesis of gout and pseudogout. Annual Meeting of the Royal College of Physicians and Surgeons of Canada, Toronto, January 27, 1977. Fam AG, Stein J, Pritzker KPH, Little AH: Hydroxyapatite arthropathy: a clinical study of 11 "probable" cases. Annual Meeting of the Royal College of Physicians and Surgeons of Canada, Toronto, January 28, 1977 and XIV International Congress of Rheumatology, San Francisco, California, June 28, 1977. Pritzker KPH, Nyburg SC: Intervertebral disc calcifications in the elderly: calcium pyrophosphate: dihydrate arthropathy. International Academy of Pathology, Toronto, March 16, 1977 and Canadian Congress of Laboratory Medicine, Hamilton, Ontario, June 28, 1977. Goldberg M, Noyek AM, Pritzker KPH: Laryngeal granuloma secondary to gastroesophageal reflux. Canadian Otolaryngological Society, Montebello, Quebec, June 2, 1977. Ziv I, Langer F, Halloran P, Pritzker KPH, Gross AE: Studies on the immunogenicity of allograft bone. Canadian Orthopedic Research Society, Toronto, June 13, 1977. Vozis EE, Pritzker KPH: Islet cell tumour of childhood - a case report with ultrastructural study. Canadian Congress of Laboratory Medicine, Hamilton, Ontario, June 27, 1977. Pritzker KPH: The clinicopathological spectrum of calcium pyrophosphate dihydrate arthropathy. Ontario Association of Pathologists, London, Ontario, September 30, 1977.* Pritzker KPH, Nyburg SC, Adams ME, Cheng P-T: The mystery of pyrophosphate arthropathy. Meeting in Honour of Professor R.H. More, Montreal, Quebec, October 14, 1977.*

25. 26. 27. 28. 29. 30. 31. 32. 33. 34.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 35. Pritzker KPH, Nyburg SC, Adams ME, Cheng P-T: Calcium pyrophosphate dihydrate crystal synthesis in

cell free gels. 29th Annual Interurban Arthritis Society Meeting, Buffalo, New York, September 24, 1977. Adams ME, Pritzker KPH, Nyburg SC, Cheng P-T: Ultrastructural approaches to the diagnosis of apatite arthropathy. 29th Annual Interurban Arthritis Society Meeting, Buffalo, New York, September 24, 1977. Pritzker KPH, Nyburg SC, Cheng P-T, Adams ME: The search for apatite arthropathy. Royal College of Physicians and Surgeons of Canada, Vancouver, BC, January 26, 1978.* Pathogenesis of gout and pseudogout. VII Panamerican Congress of Rheumatology, Bogota, Columbia, June 19, 1978.* Greyson ND, Houpt JB, Pritzker KPH, Rosen P: Bone scanning in diagnosis of spontaneous osteonecrosis of the knee. Canadian Association of Rheumatology, Toronto, Ontario, May 4, 1978. Postnikoff IM, Pritzker KPH: Hereditary angioneurotic edema: maternal mortality case. VII International Meeting of the International Association of Forensic Sciences, Witchita, Kansas, May 22, 1978. Gross AE, Langer F, Rorabeck CH, Blackstein M, Pritzker KPH: Large fragment osteochondral allotransplantation. The Canadian Association of Clinical Surgeons and Ontario University Surgeons, Toronto, June 1978.* Gordon AS, Pritzker KPH, Berris B, Britt BA: Malignant hyperthermia is more common than we think. IV International Congress of Neuromuscular Diseases, Montreal, Quebec, September, 1978. Pritzker KPH, Adams ME, Cheng P-T, Nyburg SC: Calcium pyrophosphate dihydrate crystal formation in gels and solutions. Royal College of Physicians and Surgeons of Canada, Montreal, Quebec, February 8, 1979.* Fam AG, Little AH, Gertzbein S, Pritzker KPH: Cholesterol associated synovitis: a clinico-pathologic study of eight patients. Royal College of Physicians and Surgeons of Canada, Montreal, Quebec, February 8, 1979. Cheng P-T, Pritzker KPH: Calcium pyrophosphate chemistry and calcium pyrophosphate dihydrate crystal arthropathy. Calcium and Bone Club, Toronto, February 20, 1979.*

36. 37. 38. 39. 40. 41. 42. 43. 44. 45.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 46. Brock RM, Langer F, Gross AE, Pritzker KPH, Houpt JB: Fresh allograft joint resurfacing with small and

large fragments. American Academy of Orthopedic Surgeons, San Francisco, California, U.S.A., February, 1979. Pritzker KPH, Cheng P-T, Nyburg SC, Adams ME: Micro-x-ray diffraction: definitive crystal identification in tissue sections. International Academy of Pathology, San Francisco, California, March 6, 1979. Cheng P-T, Nyburg SC, Omar SA, Pritzker KPH: Crystallography in clinical and experimental studies of calcium pyrophosphate crystal formation. American Crystallographic Association, Honolulu, Hawaii, March 27, 1979. Pritzker KPH, Cheng P-T, Omar SA, Khoury M, Nyburg SC: Calcium pyrophosphate crystal formation in gels: Cartilage as a gel.3lst Annual Interurban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 7, 1979. Cheng PT, Pritzker KPH: The physical chemistry of pseudogout. 31st Annual Interurban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 76, 1979. Application of scanning and transmission electron microscopy, x-ray energy spectroscopy and x-ray diffraction to calcium pyrophosphate crystal formation in vitro. Scanning Electron Microscopy, 1979, Washington, DC, April 18, 1979. Pritzker KPH, Adams ME, Cheng P-T, Omar SA, Cruikshank B: Black synovium. Canadian Congress of Laboratory Medicine, Quebec, Quebec, June 18, 1979. Lambert JR, Luk SC, Pritzker KPH: Lipofuscinosis of the ileum in Crohn’s disease. Canadian Congress of Laboratory, Quebec, Quebec, June 18, 1979. Pritzker KPH, Renlund RC, Cheng P-T: Calcium pyrophosphate crystal arthropathy in femoral heads. International Academy of Pathology, New Orleans, Louisiana, February 26, 1980. Pritzker KPH: Crystalline arthropathies: what’s new in old joints. 37th Annual Meeting, American Geriatric Society, Chicago, Illinois, U.S.A., April 16, 1980.* Pritzker KPH, Cheng P-T, Omar SA, Nyburg SC: Articular cartilage as a model gel for the study of calcium pyrophosphate crystal formation. Royal College of Physicians and Surgeons of Canada and the Canadian Rheumatism Association, Ottawa, Ontario, June 5, 1980.

47. 48. 49. 50. 51. 52. 53. 54. 55. 56.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 57. Arbetman RA, Pritzker KPH: Post-traumatic dysplasia of bone. Canadian Congress of Laboratory Medicine, St. John’s, Newfoundland, June 23, 1980.

Renlund RC, Pritzker KPH, Cheng P-T, Read DH, Harrington DD: Calcium stearate crystals in canine liver and adrenal gland. Canadian Congress of Laboratory Medicine, St. John’s, Newfoundland, June 24, 1980. Pritzker KPH: Crystal identification in pathologic tissues. Ontario Society of Medical Technologists, Toronto, September 24, 1980.* Sweet JM, Cheng P-T, Pritzker KPH: Oxalate crystals in granulomas, subclinical oxalosis? Ontario Association of Pathologists, 43rd Annual Meeting, Kingston, Ontario, September 26, 1980. (O.A.P. Prize for Best Resident Paper). Arbetman R, Gordon AS, Bilbao JM, Pritzker KPH: Midline meningeal mass: a manifestation of myeloproliferative malignancy. Ontario Association of Pathologists, 43rd Annual Meeting, Kingston, Ontario, September 26, 1980. Pritzker KPH: Crystalline arthropathies - 1980. University of Ottawa, Ottawa, Ontario, October 3, 1980.* Tenenbaum J, Pritzker KPH, Gross AE, Cheng P-T, Renlund RC: The effects of intra-articular corticosteroids on articular cartilage. Symposium on: Inflammatory Aspects of Osteoarthritis, Palm Air, Florida, October 23, 1980.* Cheng P-T, Pritzker KPH: Renal calculi analysis by x-ray diffraction. Calcium and Bone Club, Toronto, October 28, 1980.* Cheng P-T, Drop SW, Miller DR, Pittaway AL, Porter CJ, Pollard S, Pritzker KPH: Comparison of chemical and spectroscopic methods in renal analyses: an interhospital study. Toronto Society of Clinical Chemists, April 16, 1980. Houpt JB, Alpert B, Lotem M, Greyson ND, Pritzker KPH, Langer F, Gross A: Spontaneous osteonecrosis of the medial tibial plateau. American Rheumatism Association, Northeastern Regional Meeting, New York, N.Y., November 14, 1980.* Cheng P-T, Pritzker KPH, Tausch J, Pittaway A, Millard J: Analytical scanning electron microscopy and x-ray microdiffractometry of renal calculi using etched plastic sections. Scanning Electron Microscopy/1981, Dallas, Texas, USA, April 16, 1981.

58. 59. 60. 61. 62. 63. 64. 65. 66. 67.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 68. Pritzker KPH, Gross AE, Houpt JB: Femoral condyle osteonecrosis. International Academy of Pathology, Chicago, Illinois, U.S.A., March 3rd, 1981.

Houpt JB, Alpert A, Greyson ND, Pritzker KPH, Gross AE: The clinical spectrum of spontaneous osteonecrosis of the knee. 33rd Annual Inter Urban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 4, 1981. Cheng P-T, Pritzker KPH: The importance of magnesium ions in calcium pyrophosphate crystal formation. 33rd Annual Inter Urban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 4, 1981. Tenenbaum J, Pritzker KPH: Hydrolysis of phosphate-containing substrates in degenerative arthritis. 33rd Annual Inter Urban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 4, 1981. Wilkinson S, Houpt JB, Pritzker KPH, Gross AE: Bilateral avulsions of quadriceps tendons. 33rd Annual Inter Urban Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, April 4, 1981. Cheng P-T, Pritzker KPH: The effect of calcium and magnesium ions on calcium pyrophosphate crystal formation. Clinical Research Society of Toronto, Toronto, May 9, 1981. Geddie W, Berry W, Pritzker KPH: Selective type ii muscle fibre injury in myophosphorylase deficiency (McArdle’s Disease). Canadian Congress of Laboratory Medicine, Toronto, June 16, 1981. Sheman SL, Freeman JL, Alberti TW, Holgate R, Pritzker KPH: Ossifying hemangioma of maxilla and ethmoid sinuses. 35th Annual Meeting, Canadian Otolaryngological Society, Sherbrooke, Quebec, June 17, 1981. Renlund RC, Pritzker KPH: Effects of intra-articular hyaluronidase on articular tissues: a light and electron microscopic study. 1st International Symposium on Hyaluronidase, Rotterdam, Netherlands, June 18, 1981. Houpt JB, Alpert B, Greyson ND, Lotem M, Pritzker KPH, Gross AE: Natural history of spontaneous osteonecrosis of the knee. 15th International Congress of Rheumatol, Paris, France, June 25, 1981.* Pritzker KPH, Cheng P-T: Clinical pathologic aspects of crystal deposits. Symposium on Crystallography in the Health Sciences: Crystalline Deposits in Human Tissues, Toronto, Canada, August 13, 1981.*

69. 70. 71. 72. 73. 74. 75. 76. 77. 78.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 79. Cheng P-T, Adams ME, Nyburg SC, Pritzker KPH: Effect of various ions on calcium pyrophosphate crystal formation. Symposium on Crystallography in the Health Sciences: Crystalline Deposits in Human Tissues, Toronto, Canada, August 14, 1981.*

Sweet JM, Pritzker KPH, Cheng P-T: Calcium oxalate crystals in granulomas. Symposium on Crystallography in the Health Sciences: Crystalline Deposits in Human Tissues, Toronto, Canada, August 13, 1981. Tenenbaum J, Kandel RA, Pritzker KPH: Alkaline phosphatase and pyrophosphatase activity in articular cartilage. American Rheumatism Association, Northeastern Regional Meeting, Montreal, Qu bec, October 23rd, 1981. Cheng P-T, Houpt JB, Tagliabracci L, Pritzker KPH: Effect of pH in biomineralization. Calcium and Bone Club, Toronto, November 24, 1981. Pritzker KPH: Chondrocalcinosis and calcium pyrophosphate arthropathy. Forum Club, Toronto, December 5, 1981.* Kliman M, Gross A, Pritzker KPH, Greyson D: Osteochondritis of the hallux sesamoid bones. American Orthopaedic Foot Society Inc., New Orleans, USA, January 26, 1982. Langer F, Gross AE, Pritzker KPH: Scientific basis for joint allografting. American Academy of Orthopaedic Surgeons, New Orleans, USA, January 26, 1982.* Pritzker KPH: Comparative pathology of calcium pyrophosphate dihydrate crystal arthropathy. International Academy of Pathology, Boston, Mass., USA, March 3, 1982.* Cheng P-T, Pritzker KPH, Kandel RA, Reid A: Analytical scanning and transmission electron microscopy and x-ray microdiffractometry of calcium pyrophosphate dihydrate crystal deposits in tissues. Scanning Electron Microscopy 1982, Anaheim, California, USA, April 27, 1982. Pritzker KPH: Functional morphology of synovial joints. Medio Articular Normal Y Patalogico. Artroscopia, Universidad de Chile, Santiago, Chile, April 26, 1982.* Pritzker KPH: Cartilage and synovial pathology in osteoarthritis. Medio Articular Normal Y Patalogico. Artroscopie, Universidad de Chile, Santiago, Chile, April 27, 1982.* Pritzker KPH: Synovial and cartilage pathology in rheumatoid arthritis. Medio Articular normal Y Patalogico. Artroscopia, Universidad de Chile, Santiago, Chile, April 28, 1982.*

80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 91. Pritzker KPH: Pathologic aspects of crystal associated arthritis Medio Articular Normal Y Patalogico. Artroscopia, Universidad de Chile, Santiago, Chile, April 29, 1982.*

Pritzker KPH: Experimental approaches to calcium pyrophosphate dihydrate crystal arthropathy. Medio Articular Normal Y Patalogico. Artroscopia, Universidad de Chile, Santiago, Chile, April 29, 1982.* Pritzker KPH: Osteonecrosis: a heterogenous clinical and pathologic disease process. Sociedad Chilena de Rheumatologia, Santiago, Chile, April 27, 1982.* Pritzker KPH: Joint and bone transplantation. Grand Rounds, Hospital Del Salvador, Santiago, Chile, April 30, 1982.* Pritzker KPH: Pathological calcification of articular cartilage. Symposium on Mineralization, Faculty of Dentistry, University of Toronto, May 28, 1982.* Cheng P-T, Pritzker KPH, Tagliabracci L, Millard J, Reid A: Crystal and stone analysis. Canadian Society of Clinical Chemists, Toronto, Canada, June 16, 1982.* Kandel RA, Pritzker KPH, Langer F, Gross AE: The pathology of massive osseous grafts. Canadian Congress of Laboratory Medicine, Vancouver, BC, June 21, 1982.

Geddie WA, Stone RA, Pritzker KPH: Mesenchymoma of the liver, a borderline malignancy. Canadian Congress of Laboratory Medicine, Vancouver, BC, June 22, 1982.

Pritzker KPH: The general pathology of calcium pyrophosphate crystals. Department of Pathology, Queen’s University, Kingston, Ontario, August 13, 1982.*

92. 93. 94. 95. 96. 97. 98. 99. 100. Pritzker KPH, Renlund RC, Cheng P-T: Which comes first - osteoarthritis or crystals. Workshop on

Clinical Patterns and Pathologic Features in Osteoarthritis, Kingston, Ontario, August 13-15, 1982.* 101. Pritzker KPH: Which comes first - osteonecrosis or osteoarthritis? Workshop on Clinical Patterns and

Pathologic Features in Osteoarthritis, Kingston, Ontario, August 13-15, 1982.* 102. Gordon AS, Pritzker KPH, Britt BA: The caffeine contracture test in unexplained elevations of SEM

creatinine kinase (CK). 5th International Congress on Neuromuscular Diseases, Marseille, France, September 15th, 1982.

103. Kandel RA, Cheng P-T, Pritzker KPH: Apatite synovitis. Ontario Association of Pathologists, Peterborough, Ontario, September 24th, 1982.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 104. Tenenbaum J, Sukenik S, Houpt JB, Pritzker KPH: Synovial fluid lactate in acute crystal-associated arthropathy. American Rheumatism Association, Northeastern Regional Meeting, Boston, Massachusetts, October 28 & 29, 1982. 105. Tenenbaum J, Rogakou C, Pritzker KPH: Lapine articular chondrocytes in long term culture:

morphologic features. American Rheumatism Association, Northeastern Regional Meeting, Boston, Massachusetts, October 28 & 29, 1982. 106. Renlund RC, Kandel RA, Cheng P-T, Rapley WA, Mehren KG, Pritzker KPH: Calcium pyrophosphate

dihydrate crystal deposition disease with concurrent skeletal hyperostosis in a barbary ape (Macaca sylvanus). Annual Convention of the American Association of Zoo Veterinarians, New Orleans, Louisiana, November 12, 1982. 107. Cheng P-T, Pritzker KPH: Pyrophosphate phosphate ion interaction and the pathogenesis of

chondrocalcinosis (CPPD) and HA crystal deposition diseases. Inter-Urbain Arthritis Society Meeting, Niagara-on-the-Lake, Ontario, November 13, 1982. 108. Kandel RA, Ganel A, Langer F, Gross AE, Pritzker KPH: Histopathology of osteoarticular shell allografts. International Academy of Pathology, Atlanta, Georgia, March 1, 1983. 109. Kandel RA, Pritzker KPH, Langer F, Gross AE: The histopathology of large bone transplants.

American Academy of Orthopaedic Surgeons, Fiftieth Annual Meeting, Anaheim, California, March 12, 1983. 110. Cheng P-T, Pritzker KPH, Oreopoulos DR: Heterogeneity of renal stones from patients on peritoneal dialysis. IInd International Conference on Urinary Stones, Singapore, February 9, 1983. 111. Ultrastructure of renal stones from patients on peritoneal dialysis. Scanning Electron Microscopy /1983, Dearborn, Michigan, April 21, 1983. 112. Saldanha CF, Deitel M, Thomson DA, Patterson MC, Pritzker KPH: Pink urine in morbidly obese

patients after surgery. Clinical Research Society of Toronto, April 23, 1983. 113. Pritzker KPH: Crystal deposition disease 1983. Montreal General Hospital, Montreal, May 9, 1983.* 114. Reid AD, Cheng P-T, Grynpas MD, Pritzker KPH: Application of electron diffraction to crystal

identification of pathologic tissue. Microscopical Society of Canada, Chalk River, Ontario, May 9, 1983.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 115. Padmore RF, Silverstein E, Langer F, Mock D, Bedard YC, Pritzker KPH: Osseous and peripheral giant

cell granulomas in Paget’s disease. Canadian Association of Pathologists and VIIIth International Congress of Cytology, Quebec, Quebec, June 20, 1983.

116. Kandel RA, Renlund RC, Pritzker KPH: Hyaluronidase arthropathy - a new model for osteoarthritis. Canadian Association of Pathologists and VIIIth International Congress of Cytology, Quebec,Quebec, June 20, 1983.

117. Bushell MB, Halperin PF, Pritzker KPH: Cyclosporin a - a study of its effect on orthotopic bone transplantation in mice. Canadian Orthopaedic Research Society,Quebec, Quebec, June 5, 1983.

118. Rogakou CC, Tenenbaum J, Hunter GK, Langer F, Pritzker KPH: Long term monolayer culture of articular chondrocytes. Canadian Arthritis Research Society, Quebec, Quebec, June 5, 1983.

119. Hunter GK, Rogakou CC, Pritzker KPH: .Extracellular matrix synthesis by articular chondrocytes and synovial fibroblasts. 42nd Annual Symposium, Society for Developmental Biology, Irvine, California, USA, June 22, 1983.

120. Pritzker KPH: Calcium formation in pathologic states. Gordon Conference on Calcium Phosphates, Plymouth, New Hampshire, June 28, 1983.* 121. Cheng P-T, Pritzker KPH: Effect of fluoride on calcium phosphate crystal deposition. Gordon

Conference on Calcium Phosphates, Plymouth, New Hampshire, June 28, 1983.* 122. Cheng P-T, Pritzker KPH: Effects of temperature, solution Ca/P ratio and ionic strength on the

formation of calcium phosphate crystal phases. Symposium on Crystal Formation from Solutions, American Chemical Society Annual Meeting, Washington, DC, August 28 - September 2, 1983.

123. Pritzker KPH: Experimental pathology of calcium pyrophosphate dihydrate crystal deposition disease. Warner-Lambert Research Institute, Sheridan Park, Mississauga, Ontario, September 21st, 1983.* 124. Hunter GK, Cheng P-T, Grynpas MD, Pritzker KPH: Crystal growth in collagen gels - a model system

for cartilage calcification. 41st International Pittsburgh Diffraction Conference and 3rd Canadian Crystallography Conference (Joint meeting), Toronto, Ontario, October 5-7, 1983.

125. Simmons ED, Grynpas MD, Carnes D, Pritzker KPH: Use of bone density fractionation to study mineral changes in a rate model for osteoporosis. Orthopaedic Research Day, Division of Orthopaedics, University of Toronto at Mount Sinai Hospital, October 15, 1983.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 126. Saldanha CF, Deitel M, Thompson DA, Patterson MC, Pritzker KPH: Pink urine in morbidly obese

patients following operation. American College of Surgeons, Atlanta, Georgia, USA, October 17, 1983. 127. Pritzker KPH: Degenerative arthropathies in man and monkeys. Department of Anatomy, University of

Puerto Rico, School of Medicine, San Juan, Puerto Rico, January 30, 1984.* 128. Gross AE, Kandel R, Ganel A, Langer F, Pritzker KPH: Analysis of the histopathology of failed fresh

osteochondral allografts. 51st Annual Meeting of the American Academy of Orthopedic Surgeons, Atlanta, Georgia, USA, February 9, 1984. 129. Pritzker KPH, Cheng P-T, Reid AD: Calcium pyrophosphate crystal arthropathy - ultrastructural studies. International Academy of Pathology, San Francisco, California, USA, March 13, 1984. 130. Hunter GK, Grynpas MD, Cheng P-T, Pritzker KPH: Inhibition of cartilage calcification by proteoglycan. 4th Annual East Coast Connective Tissue Society Meeting, University of Connecticut, Farmington, Connecticut, USA, March 23, 1984. 131. Pritzker KPH, Hunter GK, Grynpas MD, Cheng P-T: Crystal growth in collagen gels - a model system

for the pathological calcification of cartilage. Clinical Research Society of Toronto, Toronto, March 24, 1984. 132. Simmons ED, Grynpas MD, Pritzker KPH, Harrison JE: Effects of fluoride on bone mineral. Clinical

Research Society of Toronto, Toronto, March 24, 1984. 133. Pritzker KPH, Cheng P-T: Pathogenesis of pyrophosphate arthropathy. Calcium and Bone Club, Toronto, Toronto, March 27, 1984.* 134. Cheng P-T, Pritzker KPH: Alternating crystallisation - a proposed mechanism for lamellar structure

formation in renal stones. Urolithiasis Research - 1984, Garmish-Parkentechen, Germany, April 7, 1984. 135. Grynpas MD, Landis WJ, Boyce WC, Pritzker KPH: Milk of calcium: a structural study. Scanning

Electron Microscopy 1984, Philadelphia, Pennsylvania, USA, April 18, 1984. 136. Cheng P-T, Reid AE, Millard J, Pritzker KPH: Ultrastructural studies of crystal-organic matrix relations

in renal stones. Scanning Electron Microscopy 1984, Philadelphia, Pennsylvania, USA, April 18, 1984.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 137. Simmons ED, Grynpas MD, Pritzker KPH, Harrison JE: Fluoride-induced changes in bone mineral.

Canadian Orthopedic Research Society, Winnipeg, Manitoba, June 10, 1984. 138. Hunter GK, Grynpas MD, Cheng P-T, Pritzker KPH: Inhibition of cartilage calcification by

proteoglycan: role of carboxyl groups. Gordon Conference on Proteoglycans. Plymouth, New Hampshire, USA, June 12, 1984.* 139. Pritzker KPH, Hunter GK: Proteoglycan and the age-dependence of pyrophosphate arthropathy.

Canadian Congress of Laboratory Medicine, Halifax, Nova Scotia, June 26, 1984. 140. Grynpas MD, Simmons ED, Pritzker KPH, Harrison JE: Effects of fluoride on bone. Gordon

Conference on Bone and Teeth Kimball Union, New Hampshire, USA, July 18, 1984.* 141. Reid AD, Grynpas MD, Pritzker KPH, Harrison JE: Structural changes induced by fluoride in rat bones.

Conjoint Meeting of Electron Microscopic Society of America/Microscopical Society of Canada, Detroit, Michigan, USA, August 15, 1984. 142. Cheng P-T, Grynpas MD, Pritzker KPH: Ultrastructural and analytical studies of amorphous calcium

phosphates, pyrophosphates and phosphate-pyrophosphate complexes. 13th Congress of the International Union of Crystallography, Hamburg, Germany, August 17, 1984.

143. Cheng P-T, Reid AD, Pritzker KPH: Ultrastructural studies of the organic matrix in kidney stones from children. 3rd Asia-Pacific Conference on Electron Microscopy, Singapore, August 24, 1984. 144. Hunter GK, Allen BL, Pritzker KPH: Effect of cartilage proteoglycan on hydroxyapatite formation in

collagen gels. Second International Conference on the Chemistry and Biology of Mineralized Tissues, Gulf Shores, Alabama, USA, September 9, 1984.

145. Pritzker KPH, Cheng P-T, Hunter GK, Grynpas MD, Kessler MJ, Renlund RC: In vitro and in vivo models of calcium pyrophosphate crystal formation. Second International Conference on the Chemistry and Biology of Mineralized Tissues, Gulf Shores, Alabama, USA, September 14, 1984.*

146. Pritzker KPH, Kessler MJ, Turnquist J, Renlund RC: Osteoarthritis and CPPD deposition disease in free ranging rhesus monkeys. American Rheumatism Association, Eleventh Northeastern Regional Meeting, Toronto, Ontario, October 26, 1984.

147. Hunter GK, Grynpas MD, Pritzker KPH: Role of proteoglycan in the pathogenesis of pyrophosphate arthropathy. American Rheumatism Association, Eleventh Northeastern Regional Meeting, Toronto, Ontario, October 26, 1984.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 148. Pritzker KPH: Articular and skeletal disease in aging Rhesus monkeys. University of Puerto Rico, San Juan, Puerto Rico, November 15, 1984.*

Pritzker KPH: Calcium pyrophosphate crystal arthropathy, test tubes, monkeys and man. Department of Pathology, University of Manitoba, Winnipeg, Manitoba, December 13, 1984.* Pritzker KPH: Crystal associated disease. Department of Pathology, University of Manitoba, St. Boniface Hospital, Winnipeg, Manitoba, December 14th, 1984.* Simmons ED, Grynpas MD, Pritzker KPH: Bone mineral changes in aging human cortical bone. Orthopedic Research Society, Las Vegas, Nevada, USA, January 22, 1985. Alpert B, Grynpas MD, Pritzker KPH: Qualitative changes in subchondral bone mineral in osteoarthritis. Orthopedic Research Society, Las Vegas, Nevada USA, January 22, 1985. Renlund RC, Pritzker KPH, Kessler MJ: Rhesus primates (Macaca mulatta) as a model for calcium pyrophosphate dihydrate crystal deposition disease. International Academy of Pathology, Toronto, Ontario, March 12, 1985. DiGregorio R, Pritzker KPH, Harrison J, Cheng P-T: Inhibitive effects of fluoride on soft tissue calcification. Clinical Research Society of Toronto, Toronto, Canada, March 23, 1985. Cheng P-T, DiGregorio R, Holmyard DP, Pritzker KPH: Minimization of calcium phosphate loss during aqueous processing by saturating aqueous reagents with hydroxyapatite. Canadian Microscopical Society, Fredericton, New Brunswick, May 19, 1985. Pritzker KPH: The pathology of degenerative arthritis of the spine. Department of Radiology, University of Western Ontario, London, Ontario, May 22, 1985.* Pritzker KPH: The pathology of crystal associated disease. Department of Pathology, University of Western Ontario, London, Ontario, May 23, 1985.* Pritzker KPH: Apatite and other odd crystal arthropathies. Department of Rheumatology, University of Western Ontario, London, Ontario, May 23, 1985.* Pritzker KPH: Recent advances in calcium pyrophosphate crystal arthropathy. Department of Pathology, University of Western Ontario, London, Ontario, May 24, 1985.*

149. 150. 151. 152. 153.

154. 155.

156. 157. 158. 159.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 160. Grynpas MD, Pritzker KPH, Hancock RGV: Neutron activation analysis of bulk and trace elements in

bones using a slowpoke reactor 2nd International Symposium on the Biology and Toxicology of metals using Nuclear Analytical Methods. National Laboratory, Long Island, NY, May 24, 1985. Alpert B, Grynpas MD, Pritzker KPH: Properties of subchondral bone mineral in osteoarthritis. Canadian Orthopedic Research Society, Hamilton, Ontario, June 2, 1985. Grynpas MD, Pritzker KPH, Kessler MJ: Cortical bone aging in free ranging Rhesus monkeys. American Society of Primatologists, Niagara Falls, New York, USA, June 2, 1985. Pritzker KPH, Kessler MJ, Renlund RC, Turnquist J: Degenerative arthritis in aging Rhesus Macaques. Tepperman. American Society of Primatologists, Niagara Falls, New York, USA, June 2, 1985.* Simmons ED, Grynpas MD, Pritzker KPH: Mineralization profile: a sensitive indicator of bone mineral pathology. Canadian Congress of Laboratory Medicine, Edmonton, Alberta, June 24, 1985. Cheng P-T, Pritzker KPH: Thermodynamics/kinetics of de novo calcium phosphate formation. Gordon Research Conference on Calcium Phosphates, Plymouth, New Hampshire, June 24, 1985.* Pritzker KPH: The pathology of cartilage calcification: degenerative disorders. Canadian Congress of Laboratory Medicine, Edmonton, Alberta, June 25, 1985.* Cheng P-T, Hunter GK, Pritzker KPH: In vitro inhibition of calcium pyrophosphate dihydrate crystal formation. Gordon Conference on Calcium Phosphates, Plymouth, New Hampshire, USA, June 26, 1985.* Grynpas MD, Pritzker KPH, Simmons ED, Hancock RV, Harrison JE: Is fluoridated bone different from non-fluoridated bone? IV International Conference on Matrix Vesicles, Cambridge, England, July 5, 1985. Tenenbaum HC, Holmyard D, Palangio K, Pritzker KPH: Osteogenesis in vitro: an ultrastructural study. IV International Conference on Matrix Vesicles, Cambridge, England, July 4, 1985. Deitel M, Thompson DA, Saldanha CF, Patterson MC, Pritzker KPH, Wlodarczyk S: Pink urine in morbidly obese patients following stapling gastroplasty. American College of Nutrition, Blacksburg, Virginia, USA, July 22, 1985. Pritzker KPH: Calcium pyrophosphate crystal arthropathy: from proteoglycans to primates. Departments of Biochemistry and Pathology, Rush Presbyterian St. Lukes Medical Center, September 4th, 1985.*

161. 162. 163. 164. 165. 166. 167.

168.

169. 170.

171.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 172. Pritzker KPH: Current theories of pathogenesis of calcium pyrophosphate crystal formation in tissues.

Conference on: Crystal Deposition and Dissolution in Tissues. Lugrin, France, September 28, 1985.* Pritzker KPH: Infectious etiology of early arthritis: pathophysiology and tissue approach to laboratory diagnosis. National Institutes of Health. Workshop on Infectious Etiology of Early Arthritis, Bethesda, Maryland, USA, November 20, 1985.* Grynpas MD, Cheng P-T, Tenenbaum HC, Pritzker KPH, Harrison JE: Is fluoridated bone different from non-fluoridated bone? The Osteoporosis Society of Canada and the Medical Advisory Board, Queen Elizabeth Hospital, Toronto, November 9, 1985.* *Pritzker KPH: Calcium pyrophosphate crystal arthropathy: model for pathological biomineralization Department of Pathology, University of Alberta, Edmonton, Alberta, January 10, 1986. Pritzker KPH: Biomineralization: from apatite to zoos. Department of Pathology, University of British Columbia. Vancouver, British Columbia, March 3, 1986.* Di Gregorio R, Pritzker KPH, Cheng P-T, Harrison JE: A proposed mechanism for nephrocalcinosis in the rat. Clinical Research Society of Toronto, April 4, 1986. Gross AE, Langer F, Pritzker KPH, Kandel R: A clinical and histological analysis of failed fresh osteochondral allografts. 42nd Annual Meeting of Canadian Orthopedical Association, Edmonton, Alberta, June 3, 1986. Fam AG, Schumacher HR, Clayburne G, Sieck M, Mandel N, Pritzker KPH: A comparison of 5 preparations of synthetic monosodium urate crystals (MSUC). American Rheumatism Association Annual Scientific Meeting, New Orleans, June 3-7, 1986. Katz I, Pritzker KPH, Grynpas MD: Qualitative bone mineral changes in osteoporosis. American Soc for Bone and Mineral Research, Anaheim, California, June 1986. Tallon J, Langer F, Pritzker KPH: Mixed osteoblastoma, giant cell tumor and aneurysmal bone cyst - a distinctive tumour? Canadian Congress of Laboratory Medicine, Kingston, Ontario, June 24, 1986. Manowski Z, Blackstein M, Fernandes B, Pritzker KPH: Morphologic evidence of tumour regression following chemotherapy for primary breast carcinoma. Canadian Congress of Laboratory Medicine, Kingston, Ontario, June 24, 1986. Vieth R, Kessler MJ, Pritzker KPH: Effect of age on vitamin D metabolites in serum in Cayo Santiago Rhesus Macaques. American Society of Primatology, Austin, Texas, June 30, 1986.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 184. Katz I, Pritzker KPH, Grynpas MD: Qualitative bone mineral changes in osteoporosis.

American Society for Bone and Mineral Research, Anaheim, California, June 1986. Kessler MJ, Turnquist JE, Pritzker KPH: Reduced prevalence and severity of degenerative joint diseases of the knee in caged Rhesus monkeys. XIth Congress of the International Primatological Society, Gottingen, FR Germany, July 20-25, 1986. Pritzker KPH: The Practice of Pathology in Canada - 1986. College of American Pathologists Meeting, Inn on the Park, Toronto, August 1, 1986.* Pritzker KPH, Ch teauvert J, Grynpas MD: Calcium, phosphorus, magnesium and sulphur content of osteoarthritic cartilage. The Royal College of Physicians and Surgeons of Canada, 1986 Annual Meeting, Toronto, September 24, 1986. Fam AG, Schumacher HR, Clayburne G, Sieck M, Mandel N, Pritzker KPH: A comparison of 5 preparations of synthetic monosodium urate crystals (MSUC). American Rheumatology Association, Northeastern Regional Meeting, Boston, Massachusetts, October 7th, 1986. Katz I, Pritzker KPH, Grynpas MD: Qualitative bone mineral changes in osteoporosis. 33rd Annual Meeting, Orthopaedic Research Society, January 19-22, 1987, San Francisco, California. Grynpas MD, Pritzker KPH, Kessler MJ: Age related bone changes in Rhesus monkeys. 33rd Annual Meeting, Orthopaedic Research Society, January 19-22, 1987, San Francisco, California. Pritzker KPH: Chondrocytes, chondrons, calcium, and calcification. Rush-Presbyterian-St. Luke’s Medical Center, Department of Biochemistry, Chicago, March 10, 1987.* Cheng P-T, Pritzker KPH, Richards J, Holmyard D: Artificial calculi and factitiously induced calculi in humans. Scanning Electron Microscopy 1987, Hamilton, Ontario, May 8, 1987. Pritzker KPH, Cheng P-T, Grynpas MD, Holmyard DP: Crystal associated diseases: roles of scanning electron microscopy in diagnosis. Scanning Electron Microscopy 1987, Hamilton, Ontario, May 8, 1987.* Grynpas MD, Pritzker KPH: Bones Lie. R.G.V. Hancock, 52nd Annual Meeting of the Society for American Archaeology, Toronto, May 1987.* Pritzker KPH: The diagnosis of bone and soft tissue tumors: problems and prospects. Musculo-skeletal Society Toronto, Mount Sinai Hospital, May 22, 1987.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 196. Pritzker KPH: Soft tissue and bone tumors/selected problems - slide seminar. Department of Pathology,

McMaster University, Hamilton, Ontario, May 29, 1987.* Fam AG, Schumacher HR, Clayburne G, Sieck M, Mandel N, Pritzker KPH: A comparison of 5 preparations of synthetic monosodium urate crystals (MSUC). American Rheumatism Association, Washington, DC, USA, June 9, 1987. Huckell CB, Grynpas MD, Pritzker KPH: Ageing and osteoporosis in free-ranging Rhesus monkeys. Canadian Orthopaedic Research Society, London, Ontario, June 29, 1987. Keating SL, Pritzker KPH: The role of lysozyme in articular cartilage. Canadian Congress of Laboratory Medicine, Quebec, Quebec, June 13-17, 1987. Pritzker KPH: Pathology 2037: mos or chaos. Ontario Association of Pathologists 50th Annual Meeting, Toronto, Ontario, September 18, 1987.* Keating SJ, Pritzker KPH, Gross AE: The pathology of long-standing massive osseous grafts. Ontario Association of Pathologists, Toronto, Ontario, September 18, 1987. Grynpas MD, Katz I, Pritzker KPH: Bone quality and bone quantity in osteoporosis. International Symposium on Osteoporosis, Copenhagen, Denmark, October 2, 1987.* Bayley TA, Harrison JE, Josse RG, Murray TM, Sturtridge W, Williams C, Patt N, Goodwin S, Pritzker KPH, Fornasier V: The relationships between fluoride effects on bone histology, bone mass and bone strength. International Symposium on Osteoporosis, Copenhagen, Denmark, October 2, 1987. Pritzker KPH: How should residents learn about hospital planning and management? - The laboratory physician viewpoint. Royal College of Physicians and Surgeons of Canada, Health and Public Policy Committee Invitational Conference, Bristol Place Hotel, Toronto, January 22, 1988.* Cheng P-T, Bader SM, Pritzker KPH, Grynpas MD: Fluoride affects trabecular bone more than cortical bone. 34th Annual Meeting, Orthopaedic Research Society, Atlanta, Georgia, February 1-4, 1988. Keating SJ, Pritzker KPH, Gross AE: The pathologic features of long-term massive osteochondral grafts. International Academy of Pathology, Chicago, Illinois, March 1, 1988. Pritzker KPH: Histopathology of allografts. Allografts in Orthopaedic Surgery: Banking and Clinical Applications, Department of Surgery, University of Toronto, Toronto, May 19, 1988.* Keating SJ, Pritzker KPH: The autopsy diagnosis of short-rib polydactyly syndrome type 1. Canadian Congress of Laboratory Medicine, Winnipeg, Manitoba, June 27, 1988.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 209. Lieberman I, Bogoch E, Pritzker KPH: Subchondral bone changes in the femoral heads of patients with

rheumatoid arthritis. 22nd Canadian Orthopaedic Research Society, Ottawa, June 1988. Pritzker KPH: Mineralizing mechanisms in ageing articular tissue relevance to rotator cuff degeneration. International Symposium on Rotation Cuff, University of Ottawa, September 22, 1988.* Kandel RA, Pritzker KPH, Cruz TF: Effect of fetal bovine serum and interleukin 1 on collagenase and proteoglycan production by bovine chondrocytes. Royal College of Physicians and Surgeons of Canada, Ottawa, September 24, 1988. Ch teauvert J, Grynpas MD, Kessler M, Pritzker KPH: Spontaneous osteoarthritis in a rhesus monkey population. Joint Meeting of Canadian Rheumatism Association/American Rheumatism Association, North East Section, Ottawa, September 24, 1988. Bayley TA, Muler C, Harrison J, Basualdo J, Sturtridge W, Josse R, Murray TM, Pritzker KPH: The long term treatment of steroid osteoporosis with fluoride. International Workshop of Fluoride and Bone, Niagara-on-the-Lake, Ontario, October 13, 1988.* Pritzker KPH, Grynpas MD, Harrison JE: Observed versus predicted concentrations of bone fluoride in osteoporotic patients: implications for assessment of fluoride effect. International Workshop of Fluoride and Bone, Niagara-on-the-Lake, Ontario, October 13, 1988.* Murray TM, Harrison JE, Bayley TA, Josse RG, Sturtridge WC, Chow R, Budden F, Laurier L, Pritzker KPH, Kandel R, Vieth R, Strauss A, Goodwin S: Fluoride treatment: Dose, age, and other clinical factors in the osteogenic response. International Workshop of Fluoride and Bone, Niagara-on-the-Lake, Ontario, October 12, 1988.* Pritzker KPH, Grynpas MD, Brown RD: Bone quality and bone kinetics in cyclic osteoporosis. 3rd International Conference on the Chemistry and Biological of Mineralized Tissues, Chatham, Massachusetts, October 16-21, 1988.* Kandel RA, Pritzker KPH, Cruz TF: Regulation of chondrocyte collagenase production. Midwest Connective Tissue Workshop, Chicago, IL, November 11, 1988. Cruz TF, Pritzker KPH, Kandel RA: Signal transduction mechanisms involved in the regulation of chondrocyte collagenase production. Midwest Connective Tissue Workshop, Chicago, IL, November 11, 1988. Keating S, Pritzker KPH: The production of lysozyme by chondrocytes. Midwest Connective Tissue Workshop, Chicago, IL, November 11, 1988.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 220. Pritzker KPH, Ch teauvert J, Grynpas M, Renlund R, Turnquist J and Kessler MJ: Rhesus Macaques as an experimental model for degenerative arthritis. Presented in part: 50th Anniversary Meeting

Commemorating Establishment of Cayo Santiago Rhesus Monkey Colony, San Juan, Puerto Rico, December 5, 1988.* Grynpas MD, Huckell CB, Pritzker KPH, Hancock RGV, Kessler MG: Bone mineral and osteoporosis in aging Rhesus monkeys. 50th Anniversary Meeting Commemorating Establishment of Cayo Santiago Rhesus Monkey Colony, San Juan, Puerto Rico, December 5, 1988.* Renlund DVM, Pritzker KPH, Kessler MJ: Calcium pyrophosphate dihydrate crystal deposition disease: a common disease of aging human and non-human primates. United States/Canadian Academy of Pathology, San Francisco, CA, March 6, 1989.* Tornos C, Silva E, Pritzker KPH, El-Naggar A: Calcium oxalate crystals in breast biopsies: the missing microcalcifications. United States/Canadian Academy of Pathology, San Francisco, CA, March 6, 1989. Keating S, Pritzker KPH: Aneurysmal bone cysts containing chondroid bone. United States\Canadian Academy of Pathology, San Francisco, CA, March 7, 1989. Pritzker KPH, Holmyard D, Slomovic A, Heathcote JG: The calcification of band keratopathy. The XXI European Symposium on Calcified Tissues, Jerusalem, Israel, March 14, 1989. Grynpas MD, Alpert B, Lieberman IH, Pritzker KPH: Changes in bone mineralization in osteoarthritis. The XXI European Symposium on Calcified Tissues, Jerusalem, Israel, March 14, 1989. Pritzker, KPH: Calcium pyrophosphate arthropathy. Department of Pathology Hadassah Hospital Ein Karem, Jerusalem, Israel, March 19, 1989.* Cruz T, Pritzker KPH, Kandel RA: Regulation of collagenase production: role of protein kinase C. Bat Sheva Seminar, Methods of Cartilage Research, Nof Ginosaur, Israel, March 22, 1989. Grynpas MD, Ch teauvert JMD, Pritzker KPH: Chemical analysis of osteoarthritic cartilage. Bat Sheva Seminar, Methods of Cartilage Research, Nof Ginosaur, Israel, March 23, 1989.* Pritzker KPH, Keating S: Detection of lysozyme in articular cartilage by in situ hybridization. Bat Sheva Seminar, Methods of Research in Cartilaginous Tissues. Nof Ginosaur, Israel, March 23, 1989.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 231. Pritzker KPH, Ch teauvert JMD, Kessler MJ: Prospects for the Rhesus primate spontaneous arthritis as a model degenerative arthritis. Bat Sheva Seminar, Methods of Research in Cartilaginous Tissues, Nof Ginosaur, Israel, March 24, 1989.*

Pritzker KPH, Ch teauvert JMD, Grynpas MD: Morphometric analysis of osteoarthritic cartilage. Bat Sheva Seminar, Methods of Cartilage Research, Nof Ginosaur, Israel, March 23, 1989. Grynpas MD, Ch teauvert JMD, Kessler MJ, Pritzker KPH: Morphometric studies of the articular cartilage of Rhesus Macaques with spontaneous osteoarthritis. 23rd Annual Meeting of the Canadian Orthopaedic Research Society, Research 37, Sheraton Centre, Toronto, May 28, 1989. Rudan JF, Keating S, Pritzker KPH, Farine I, Czitrom A, Gross A: Knee menisci allotransplantation: an experimental study using a rabbit model. 23rd Annual Meeting of the Canadian Orthopaedic Research Society, Research 35, Sheraton Centre, Toronto, May 28, 1989. Pritzker KPH, Xu Y, Cruz TF. Comparative analysis of phosphatase activity on dissolution of calcium pyrophosphate dihydrate crystals. Gordon Research Conference on Calcium Phosphates, Newport, Rhode Island, July 26, 1989.* Xu Y, Cruz TF, Pritzker KPH: Role of pyrophosphatase activity on dissolution of calcium pyrophosphate crystals. Gordon Research Conference on Calcium Phosphates, Newport, Rhode Island, July 26, 1989.* Murray TM, Rao LG, Ly H, Pritzker KPH, Kandel R, Derzko C, Tong J, Sturtridge W, Messner H: Generalized osteonecrosis following bone marrow transplantation. American Society of Bone and Mineral Research, Montreal, Quebec, September 9, 1989. Pritzker KPH: Degenerative changes in cartilage and cartilage grafts. Ontario Centre for Materials Research, Kingston, Ontario, December 8, 1989.* Cruz TF, Pritzker KPH, Kandel R: Effect of Interleukin 2 and phorbol esters on chondrocyte cultures. Orthopaedic Research Society, New Orleans, Louisiana, February 4-8, 1990. Kandel R, Petilycky M, Dinarello C, Minden M, Pritzker KPH, Cruz TF: Effect of IL 6 on collagenase and proteoglycan production by chondrocytes. Orthopaedic Research Society, New Orleans, Louisiana, February 4-8, 1990. Pritzker KPH: The Canadian Health Care Systems - Are they the answer? American Pathology Foundation Seminar, Tampa, Florida, February 9th, 1990.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 242. Pritzker KPH: Advances in the study of crystal formation an therapeutic possibilities, present and future.

Symposium on "Crystal Arthropathies". Panamerican Congress of Rheumatology, Guadalajara, Mexico, March 14, 1990.* Keating S, Wunder J, Andrulis I, Czitrom A, Bell R, Pritzker KPH: MDR1 gene expression in soft tissue tumours as measured by the polymerase chain reaction. United States and Canadian Academy of Pathology. Boston, Massachusetts, USA, March 5, 1990. Pritzker KPH: Advances in tetracycline labelling of bone. Bone and Mineral Group, University of Toronto, Toronto, May 22, 1990. Howarth D, Cruz T, Pritzker KPH, Kandel RA: Intracellular calcium changes in bovine chondrocytes and synovial fibroblasts. Canadian Congress of Laboratory Medicine, St. John’s, Newfoundland, June 25, 1990. Pritzker KPH: Postgraduate pathology education: past, present and future. Residency Section, Canadian Association of Pathologists, St. John’s, Newfoundland, June 23, 1990.* Pritzker KPH: Acute viral infection paralyzing a pathology department. Canadian Congress of Laboratory Medicine, St. John’s, Newfoundland, June 26, 1990. Pritzker KPH, Mendes M, Grynpas MD, Mullen JBM: Video microscopy densitometry of fluorescent bone labels. 22nd International Hard Tissue Seminar, Sun Valley, Idaho, USA, August 8th, 1990. Pritzker KPH, Ch teauvert JMD, Grynpas MD, Kessler MJ: Osteoarthritic cartilage morphometry. 22nd International Hard Tissue Seminar, Sun Valley, Idaho, USA, August 9th, 1990. Pritzker KPH: Synovial reactions to joint prosthetic products. Nu International Hard Tissue Seminar, Sun Valley, Idaho, USA, August 9th, 1990. Pritzker KPH: New insights into CPPD crystal deposition disease. 59th Annual Meeting, Royal College of Physicians and Surgeons of Canada/Canadian Rheumatism Association, Toronto, September 15, 1990.* Grynpas MD, Pritzker KPH, Very JM, Mertz B: Changes in mineralization profiles due to long term administration of APD in the dog. Third International Symposium on Osteoporosis and Consensus Development Conference Copenhagen, Denmark October 14-20, 1990. Howarth D, Cruz T, Pritzker KPH, Kandel RA: Intracellular calcium changes in bovine chondrocytes and synovial fibroblasts. John Cole Memorial Residents’ Competition, Women’s College Hospital, Toronto, February 18, 1991.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 254. Pritzker KPH, Huang X, Keating SJ: Peripheral mixed osteoblastoma. United States/Canadian

Academy of Pathology, Chicago, March 18, 1991. Kandel RA, Howarth D, Pritzker KPH, Cruz TF: Calcium ionophore A23187 increases gelatinase production by synovial fibroblasts. Orthopaed Research Society, Anaheim, CA, March 4-7, 1991. Cruz TF, Peplinsky B, Pritzker KPH, Kandel RA: Tyrosine phosphorylation of a 36 Kd protein correlates with the inhibition of collagenase production by chondrocytes. Orthopaedic Research Society Meeting, Anaheim, CA, March 4-7, 1991. Grynpas MD, Holmyard D, Pritzker KPH: Bone mineral quality in biopsies of osteoporotic patients treated with fluoride. XXII nd European Symposium on Calcified Tissues, Vienna, Austria, March 12, 1991. Xu Y, Cruz T, Pritzker: The potential role of alkaline phosphatase in dissolution of calcium pyrophosphate dihydrate crystals in articular cartilage. Clinical Research Society of Toronto Annual Meeting, Toronto, April 13, 1991. Pritzker, KPH: Bone biology for the oncologist. Calcium and Cancer: Bone-Related Complications of Malignancy, Faculty of Medicine Continuing Education, University of Toronto, Sunnybrook Health Science Centre, April 26, 1991.* Fam AGH, Pritzker KPH: Acute calcific periarthritis in scleroderma. American College of Rheumatology Northeast Meeting. Newport, Rhode Island, May 1-5, 1991. Pritzker KPH: Histopathology of osteoarthritis in humans and monkeys. International Workshop on Articular Cartilage and Osteoarthritis, Wiesbaden, Germany, May 15, 1991.* Pritzker KPH: Towards a solution for calcium pyrophosphate dihydrate crystal arthropathy. The Royal London Hospital Medical College, Bone and Joint Research Unit, May 17, 1991.* Kim S, Shinozaki T, Pilliar RM, Grynpas MD, Pritzker KPH: Calcium phosphate fibres for biodegradable implants. Canadian Biomaterials Society Annual Conference, Queen’s University, Kingston, Ontario, August 9-11, 1991. Pritzker KPH, Murray TJ: Multifocal bone necrosis restricted to osteocytes. Canadian Congress of Laboratory Medicine, Vancouver, B.C., June 27, 1991. Gahunia HK, Lemaire C, Cross, Grynpas MD, Pritzker KPH: Magnetic resonance imaging of the knee joint of Rhesus monkey: assessment of cartilage quality in osteoarthritis. 10th Annual Scientific Meeting of the Society of Magnetic Resonance in Medicine, San Francisco, CA, August 10-16, 1991.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 266. Pritzker KPH: Recent advances in the pathogenesis of calcium pyrophosphate dihydrate crystal arthropathy. Department of Medicine, University of California, San Diego, La Jolla, California, USA,

September 24, 1991.* Cerroni A, Pritzker KPH, Turnquist JE, Kessler MJ, Melbye FJ: Spontaneous malformations of the vertebral column in Patas monkeys. Canadian Association of Physical Anthropology, 19th Annual Meeting, Hamilton, Ontario, October 31, 1991. Xu Y, Pritzker KPH, Cruz TF: The potential of alkaline phosphatase in dissolution of calcium pyrophosphate dihydrate crystals in articular cartilage. 31st Meeting of the American Society for Cell Biology, Boston, Massachusetts, USA, December 8-12, 1991. Pritzker KPH, Xu Y, Cruz TF: Alkaline phosphatase: a novel therapeutic strategy for calcium pyrophosphate dihydrate crystal dissolution in cartilage. Connective Tissue Research J, 4th International Conference of chemistry and biology of mineralized tissues. Coronado, California, February 5-9, 1992.* Grynpas MD, Acito A, Kasra M, Renlund R, Pritzker KPH: The effect of pamidronate (APD) administration on canine bone. ICCRH Meeting, Florence, Italy, April 1992. Pritzker KPH: Magnetic resonance imaging of cartilage in human and Rhesus Macaque osteoarthritis. Herchel Smith Laboratory of Medicinal Chemistry, Addenbrookes Hospital, Cambridge University, Cambridge, England, May 14, 1992.* Gahunia HK, Lemaire C, Grynpas MD, Cross A, Kessler MJ, Pritzker KPH: Osteoarthritis in rhesus macaques. Assessment of cartilage matrix quality by quantitative magnetic resonance imaging. 19th ESOA Symposium, Symposium on Joint Destruction in Arthritis and Osteoarthrosis, Noordwijkerhout, The Netherlands, May 24-27, 1992. Gahunia H, Pritzker, KPH: Spontaneous degenerative osteoarthritis in Rhesus Macaques: Analytical magnetic resonance imaging studies. American Society of Primatologists, York University, Toronto, Ontario, June 19, 1992.* Grynpas MD, Gahunia H, Pritzker KPH: Cartilage collagen in Rhesus degenerative arthritis. American Society of Primatologists, York University, Toronto, Ontario, June 19, 1992. Gahunia H, Pritzker, KPH: Spontaneous osteonecrosis of the femoral condyle: a disease affecting both Rhesus and Man. American Society of Primatologists, York University, Toronto, Ontario, June 19, 1992.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 276. Pritzker KPH: Pathology requirements for teaching hospitals in the 1990’s. Canadian Congress of

Laboratory Medicine 1992, Toronto, Ontario, June 23, 1992.* Shinozaki T, Xu Y, Pritzker KPH: Features of calcium pyrophosphate dihydrate (CPPD) crystal dissolution by alkaline phosphatase. Gordon Research Conference on Calcium Phosphates. Salve Regina College, Newport, RI, USA, July 20-24, 1992.* Xu Y, Pritzker KPH, Cruz T: Dissolution of calcium pyrophosphate dihydrate crystals by chondrocyte alkaline phosphatase in articular cartilage. Gordon Research Conference on Calcium Phosphates. Salve Regina College, Newport, RI, USA, July 20-24, 1992.* Gahunia HK, Lemaire C, Grynpas MD, Cross A, Kessler MJ, Pritzker KPH: Assessment of cartilage degeneration by analytical magnetic resonance imaging. 11th Annual Scientific Meeting of the Society of Magnetic Resonance in Medicine, Berlin, Germany, August 8-15, 1992. Babyn PS, Kim HK, Cross A, Lemaire CS, Pritzker KPH, Gahunia HK: Magnetic resonance imaging of the articular-epiphyseal cartilage complex in the foreseen proximal femoral epiphysis during maturation. Scientific Meeting of the Society of Magnetic Resonance in Medicine, Berlin, Germany, August 8-15, 1992. Grynpas MD, Holmyard D, Pritzker KPH: Bone mineral quality in biopsies of fluoride treated osteoporotic patients. 6th International Congress of Bone Morphometry 1992, Lexington, Kentucky, USA, October 4 - 9, 1992. Mendes M, Pritzker KPH: Optimizing multiple fluorochrome bone histodynamic markers. 6th International Congress of Bone Morphometry 1992, Lexington, Kentucky, USA, October 8, 1992.* Pritzker KPH: CPPD deposition disease: a pathologist’s view. American College of Rheumatology, Atlanta, GA, USA, October 12, 1992.* Pritzker KPH: Osteoarthritis: What can monkeys teach man? University of Hong Kong, Hong Kong, October 23, 1992.* Gahunia H, Lemaire C, Kessler MJ, Pritzker KPH: Analytical magnetic resonance imaging and cartilage water quality: studies on the Rhesus Macaque osteoarthritis model. Mid-West Connective Tissue Meeting, Chicago, Illinois, USA, October 23-24, 1992. Pritzker KPH: Biomineralization disorders in the aged: osteoporosis and calcium pyrophosphate arthropathy. Department of Pathology, The Chinese Medical University of Hong Kong, October 30, 1992.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 287. Pritzker KPH: The future of laboratory practice. University of Ottawa, Department of Pathology,

November 20, 1992.* Pritzker KPH: Primate arthritis. Arthritis Day, University of Toronto, December 1, 1992.* Berkovitch, Laxer RM, Matsui D, Fritzler MJ, Hedden D, Pilavdzic D, Koren G, Klein J, Templeton DM, Pritzker KPH, Olivieri NF: Analysis of adverse rheumatologic effects of iron chelators in patients with homozygous beta thalassemia (HBT). American Society of Hematology 34th Meeting. Anaheim, CA, December 4-8, 1992. Pritzker KPH, Gahunia HK, Kessler MJ: Rhesus Macaque osteoarthritis: cartilage water quality. First International Congress of the Osteoarthritis Research Society, Paris, France, December 10 - 13, 1992. Babyn P, Kim H, Lemaire C, Pritzker KPH, Cross A, de Nanassy J: High resolution magnetic resonance imaging of porcine articular-epiphyseal complex maturation. Orthopedic Research Society, San Francisco, February 1993. Kim HKW, Babyn PS, Hasiewicz K, Pritzker KPH, Foster FS: High resolution imaging of articular cartilage using ultrasound backscatter microscopy. Orthopedic Research Society, San Francisco, February, 1993. Pilavdzic D, Olivieri NF, Pritzker KPH: Synovial pathology in -thalassemia. United States and Canadian Academy of Pathology, New Orleans, LA, March 16, 1993. Pritzker KPH: Osteoarthritis and calcium pyrophosphate dihydrate crystal deposition disease: a pathologist’s perspective. 12th Annual Meeting of the Paleopathology Association, Toronto, Canada, April 14, 1993.* Babyn P, Kim H, Pritzker K, de Nanassy J, Lemaire C: High resolution imaging of the articular epiphyseal cartilage complex with ischemic damage. Society of Pediatric Radiology. Seattle, Washington, May 12-15, 1993. Kim S, Shinozaki T, Pilliar RM, Grynpas MD, and Pritzker KPH: Enzymatic degradation of calcium metaphosphate glasses - The effects of Ca/P ratios. Canadian Biomaterials Society. Hamilton, Ontario, June 3, 1993. Solez K, Bernier V, Cullen J, Daya D, Gray G, Haegert D, Kalra J, Mikhael N, Pritzker K, Silver M, Sweet J, Waldorf V: The image of pathology: economics, recruitment, training and practice. Report on the future of pathology and laboratory medicine in Canada. Consortium Nucleus Committee. Canadian Association of Pathologists, 44th Annual Meeting. Banff, Alberta, June 26-30, 1993.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 298. Fernandes B, Abbott D, Pritzker K, Musclow E, Ray P and Atkinson J: Improved laboratory

systemization in Haematology. Canadian Association of Pathologists, 44th Annual Meeting. Banff, Alberta, June 26-30, 1993.* Schumacher HR, Pritzker K, Terkeltaub R, Mizraji M: Crystal identification, formation, dissolution, and associated inflammation. XVIIIth ILAR Congress of Rheumatology. Barcelona, Spain, July 4-9, 1993.* Pritzker K: Calcium pyrophosphate crystal formation, deposition, and dissolution. XVIIIth ILAR Congress of Rheumatology. Barcelona, Spain, July 4-9, 1993.* Pritzker K: Enfermedades por depositos de cristales y el patologo. XVIIIth ILAR Congress of Rheumatology. Barcelona, Spain, July 4-9, 1993.* Dieppe P, Watt I, Pritzker KPH: Calcium pyrophosphate deposition disease, a process not a disease. The International Skeletal Society, 20th Annual Refresher Course, Toronto, Ontario, August 18-21, 1993.* Fernandes B, Abbott D, Pritzker K, Musclow E, Ray P, Atkinson J: Evaluation of the Sysmex HS-302 "Total Hematology System". The 38th Annual Scientific Meeting of The Royal College of Pathologists of Australia, Perth, Australia, Sept 27-Oct 1, 1993. Boerner S, Pritzker KPH: Sarcomas in Paget’s Disease of Bone. Ontario Association of Pathologists, 56th Annual Meeting, Kingston, Ontario, September 30, October 1, 2, 1993. Guo W, Kim S, Grynpas MD, Pritzker KPH, Pilliar RM: Calcium Polyphosphate Fibres for Composite Biomaterials - Degradation Studies. The 20th Annual Meeting of the Society for Biomaterials, Boston, MA, April 5-9, 1994. Pritzker KPH: Joint Pathology with Special Reference to Temporomandibular Joint. Faculty of Dentistry, University of Toronto, March 24, 1994.* Grynpas MD, Renlund R, Pritzker KPH: The localization of pamidronate (APD) in bone. Second Workshop on Bisphosphonates. From the laboratory to the patient. Davos, Switzerland, April 14-17, 1994. Grynpas MD, Holmyard D, Nespeca R, Pritzker KPH: Bone mineralization and histomorphometry from biopsies of patients treated with fluoride. Scanning Microscopy International, Toronto, Ontario, May 7- 12, 1994.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 309. Shinozaki T, Pritzker KPH: Implications of alkaline phosphatase pyrophosphatase activity: Intracellular

functions of alkaline phosphatase. The 9th Annual Orthopedic Research Meeting of the Japanese Orthopedic Association. Kobe, Japan, October 1994.* Lim KKT, Kessler M, Pritkzer K, Dieppe PA: Nodal swellings and osteoarthritis in the finger joints of elderly monkeys. British Society of Rheumatology. England, October 1994 Pritzker KPH: Pacific Bridge Project. An Introduction. The XX International Congress of the International Academy of Pathology. Hong Kong, October 11, 1994.* Pritzker KPH: Advances in the Biology of Osteoporosis. The 3rd Joint Meeting of the International Academy of Pathology (IAP) Chinese Division & Chinese Society of Pathology, CMA. Guangzhou, China, October 16, 1994.* Pritzker KPH: Advances in the Biology of Soft Tissue and Bone Tumours. The 3rd Joint Meeting of the International Academy of Pathology (IAP) Chinese Division & Chinese Society of Pathology, CMA. Guangzhou, China, October 16, 1994.* Pritzker KPH: Pacific Bridge Project. Molecular Epidemiology of Cancers in Asian Populations. Cancer Centre of the Department of Pathology. National Yang Ming University. Taipei, Taiwan, October 20, 1994.* Lim KKT, Kessler M, Pritzker K, Dieppe PA: Osteoarthritis of the hand in a non human primate. Second International Osteoarthritis Research Society Congress, Orlando, Florida, December 1994. Babyn P, Gahunia HK, Harasiewicz K, Foster FS, Kim HKW, Pritzker KPH: Ultrasound backscatter microscopy (UBM) of normal and osteoarthritic articular cartilage at 50 MHz. Second International Osteoarthritis Research Society Congress, Orlando, Florida, December 1994.

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313.

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317. Pritzker KPH, Gahunia H, Babyn P, Lemaire C, Kessler MJ: Assessment of osteoarthritis staging: Severity correlation between radiographic imaging and pathology. Second International Osteoarthritis Research Society Congress, Orlando, Florida, December 1994.*

318. Gahunia HK, Lemaire C, Babyn P, Cross A, Kessler MJ, Pritzker KPH: Qualitative and quantitative analysis of osteoarthritic cartilage lesions using magnetic resonance imaging. Second International Osteoarthritis Research Society Congress, Orlando, Florida, December 1994.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 319. Grynpas MD, Renlund R, Pritzker KPH: The effect of pamidronate in a new model of immobilization in

the dog. XIIth International Conference on Calcium Regulating Hormones. Melbourne, Australia. February 14-19, 1995. Pritzker KPH and Rothschild B: Ankylosing Spondylosis with Disc Calcifications. Paleopathology Club. United States and Canada Academy of Pathology. Toronto, Ontario, March 12, 1995.* Pritzker KPH: Bone tumors with giant cells: Pathogenesis, Pathology and Prognosis. Bone and Soft Tissue Disease Symposium. The 4th Congress of the Asia Pacific Association of Societies of Pathology, Beijing, China, May 9, 1995.* Pritzker KPH: Osteoporosis: Biology and Laboratory Assessment. Department of Pathology, Kanazawa University, Kanazawa, Japan, May 15, 1995.* Pritzker KPH: Osteoporosis: Disorder of Bone Mineralization. Department of Pathology, University of Tokyo, Tokyo, Japan, May 22, 1995.* Pritzker KPH: Sarcomas: Dilemmas of Diagnosis. Department of Pathology, Kyushu University, Kyushu, Japan, May 23, 1995.* Pritzker KPH: The future of Canadian Pathology and Laboratory Medicine: Towards a Patient Centred Paradigm for Diagnostic Biology. Special Joint Meeting organized by the Japanese Association of Pathologists, the Japanese Society of Pathology, The Japanese Division of IAP, the College of Clinical Pathology and the University of Tokyo. Department of Pathology, Tokyo Jikeikai University School of Medicine, Tokyo, Japan, May 26, 1995.* Pritzker KPH: Osteoarthritis: The rhesus macaque model and its relation to human osteoarthritis.

Department of Pathology, Hokkaido University School of Medicine, Sapporo, Japan, May 29, 1995.* Pritzker KPH: Alkaline phosphatase: potential molecular therapy for crystal arthropathy. Departments of Pathology and Orthopedic Surgery, Gunma, Japan, June 5, 1995.* Pritzker KPH: Laboratory Systemization in Canada. Sysmex TOA Medical Electronics, Techno-Center (R & D), Kobe, Japan, June 8, 1995.* Pritzker KPH: Biology of Bone. Congress of the "Sociedad Chilena de Osteologia", Santiago, Chile, August 4-5, 1995.* Pritzker KPH: Osteoporosis and Osteoarthritis. An Antagonistic Relation? Congress of the "Sociedad Chilena de Osteologia", Santiago, Chile, August 4-5, 1995.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 331. Shinozaki T, Pritzker KPH: Alkaline phosphatase, pyrophosphatase activity, and calcium pyrophosphate

dihydrate crystal dissolution. Fifth International Conference on the Chemistry and Biology of Mineralized Tissues, Kohler, Wisconsin, October 22-27, 1995 Pritzker KPH, Lee J-Y, Mendes M: Tetracycline surfaces can exceed osteoid surfaces: Implications for bone mineralization. Fifth International Conference on the Chemistry and Biology of Mineralized Tissues, Kohler, Wisconsin, October 22-27, 1995 Wang R-n, Cai, J-c, Hiruki T, Pritzker KPH, Redston M, Bapat BV: Microsatellite instability in gastric carcinomas in China. 85th Annual Meeting of the United States and Canadian Academy of Pathology, Washington, D.C., March 23-29, 1996 Fan Q-h, Allen PW, Pritzker KPH: Spindle cell hemangioendothelioma. Ontario Association of Pathologists, 59th Annual Meeting, Toronto, Ontario, June 7-8, 1996 Agur A, Y cel Y, McKee N, Salonen D, Ashby P, Pritzker KPH: Selective fatty infiltration of the soleus and medial head of gastrocnemius muscles. American Association of Clinical Anatomists. Omaha, Nebraska, June 12-14, 1996. Pritzker KPH: Innovative Changes in Ontario Laboratories. The people issues, quality of service issues, quality of test results. Clinical Laboratory Management Association Trillium Chapter, Durham Board of Education Centre, Whitby, Ontario, October 18, 1996.* McKee N, Agur A, Yucel Y, Salonen D, Ashby P, Pritzker KPH: Selective fatty replacement of gastrocnemius and soleus muscles. 42nd Annual Meeting of the Plastic Surgery Research Council, Galveston, Texas, February 26 - March 1, 1997. Gahunia KH, Lemaire C, Konyer NB, Babyn PS, Kim HKW, Pritzker KPH: High resolution magnetic resonance imaging of reconstituted articular cartilage. Proceedings of the International Society for Magnetic Resonance in Medicine. Fifth Scientific Magnetic Resonance in Medicine, Vancouver, BC, April 12-18, 1997. Volume 2, p. 1035. Gahunia KH, Harasiewicz K, Lemaire C, Konyer NB, Kim HKW, Foster SF, Babyn PS, Pritzker KPH: High resolution magnetic resonance imaging of interleukin-1 treated reconstituted articular cartilage: Comparison with high frequency ultrasound imaging and histology. Proceedings of the International Society for Magnetic Resonance in Medicine. Fifth Scientific Magnetic Resonance in Medicine, Vancouver, BC, April 12-18, 1997. Volume 2, p. 1034. Gahunia HK, Lemaire C, Pritzker KPH: Magnetic resonance imaging of reconstituted articular cartilage. Third Canadian Connective Tissue Conference, Queen’s University, Kingston, Ontario, May 23-24, 1997.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 341. Holmyard DP, Shinozaki T, Pritzker KPH: FE-SEM examination of calcium pyrophosphate dihydrate

crystal dissolution. 24th Annual Meeting of the Microscopical Society of Canada, Edmonton, Alberta, June 4-7, 1997. Pritzker KPH: Cancer Genetics Amongst Chinese in Hong Kong, China and Canada. Canadian Chamber of Commerce, Hong Kong, June 6, 1997.* Gahunia HK, Harasiewicz K, Foster SF, Kessler MJ, Pritzerk KPH: High frequency ultrasound imaging of normal and osteoarthritic rhesus macaque knee joints. Third International Osteoarthritis Research Society Meeting, Singapore, June 7-9, 1997. Gahunia HK, Harasiewicz K, Lemaire C, Foster SF, Pritzker KPH: Interleukin-1 induced damage to reconstituted articular cartilage: Assessment by magnetic resonance and ultrasound imaging. Third International Osteoarthritis Research Society Meeting, Singapore, June 7-9, 1997. Gahunia HK, Lemaire C, Pritzker KPH: Reconstituted articular cartilage: Characterization by magnetic resonance imaging. Third International Osteoarthritis Research Society Meeting, Singapore, June 7-9, 1997. Peters WJ, Pritzker KPH, Smith DC, Ibanez D, Fornasier V: Calcification of 404 silicone-gel breast implant capsules. Canadian Society of Aesthetic, Cosmetic, Plastic Surgery Annual Meeting, Vancouver, BC, September 1997. Pritzker KPH: In vitro MR and ultrasound imaging of cartilage. The International Skeletal Society Meeting, Santa Fe, New Mexico, September 10-13, 1997.* Harasiewicz KA, Gahunia HK, Lemaire C, Konyer NB, Kim HKW, Babyn PS, Pritzker KPH, Foster FS: Ultrasound biomicroscopy and magnetic resonance imaging of reconstituted articular cartilage. 1997 IEEE International Ultrasonics Symposium, Toronto, Ontario, October 5-8, 1997. Pritzker KPH: Osteoporosis biology - current advances. 110 th Anniversary Celebration Scientific Congress of the University of Hong Kong, Hong Kong, October 24-26, 1997.*

Pritzker KPH: Cartilage pathology: arthritis and transplantation. IV Joint Conference of the International Academy of Pathology Chinese Division and Chinese Society of Pathology, CMA, Shanghai, October 28-31, 1997.* Pritzker KPH: Better, faster, cheaper: quality trends in Canadian health care, Shanghai Second Medical University, Shanghai, October 30, 1997.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 352. Pritzker KPH: Towards integrated health systems in Canada, Yangpu Health Bureau, Shanghai, October 30, 1997.*

Peters WJ, Pritzker KP, Smith DC, Fornasier V, Lugowski SS: Capsular calcification in saline gel breast implant capsules - a 19-year study. American Society for Aesthetic Plastic Surgery, Los Angeles, California, May 1998. Pritzker KPH: Recent advances in calcium pyrophosphate crystal arthropathy. Institut f r Pathologie, Universit t Giessen, June 19, 1998.* Pritzker KPH: rhIGF-1 effects on articular cartilage histology. Chiron Technologies Inc., Emeryville, California, October 3, 1998.* Pritzker KPH: Histopathological grading of osteoarthritis. International, Florence, Italy, October 15-17, 1998.* Osteoarthritis Research Society

353.

354. 355. 356. 357. Peters WJ, Pritzker KP, Smith DC, Fornasier V: Capsular calcification associated with silicone gel and

saline breast implants. Research Forum. American Society for Plastic and Reconstructive Surgery, Boston, Mass. October 1998. Liu R, O’Connell M, Johnson K, Pritzker K, Mackman N, Terkeltaub R: Activation of both NF-kB and the map kinase ERK1/2 (P44/42) are essential for urate crystal (UC) and CPPD crystal-induced expression of the chemokine IL-8 in monocytes. American College of Rheumatology 1998 National Scientific Meeting, San Diego, CA, November 8-12, 1998. Johnson K, Moffa A, Pritzker K, Chen Y, Goding J, Terkeltaub R: Up-regulation of PC-1 immediately prior to the onset of hydroxyapatite deposition is essential for osteoblasts to effectively mineralize their matrix. American College of Rheumatology 1998 National Scientific Meeting, San Diego, CA, November 8-12, 1998. Pritzker KPH: Pathogenesis of osteoarthritis: New perspectives. Gunma University, Department of Orthopedic Surgery, Maebashi, Japan, March 3, 1999.* Pritzker KPH: Cartilage repair and regeneration !recent advances. University of Tokyo International Symposium: Recent advances in pathological research on some interesting diseases, Tokyo, Japan, March 5, 1999.* Wolfgang GHI, Seely L, Pike M, Hsyu P, Novicki D, Horvath C, Myers SL, Pritzker K: Efficacy and safety of recombinant human insulin-like growth factor (rhIGF-1) in a canine model of osteoarthritis. Society of Toxicology Meeting, New Orleans, March 14-18, 1999.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 363. Haber GB, Pritzker KPH, Cirocco M, Mendes MG, Parisien K, Renlund RC, Kortan PK: P 32

impregnated radioactive expandable metal stent in a dog model. 1999 Annual Meeting, Digestive Diseases Week, Orlando, Florida, May 16-19, 1999. Sali A, Favaloro JM, Pritzker K, Terkeltaub R, Goding JW: Germline detection of the nucleoside triphosphate pyrophosphohydrolase (NTPPPH) plasma cell membrane glycoprotein 1 (PC-1) produces abnormal calcification of periarticular tissues. International Ecto-ATPase meeting, Brussels, Belgium, June 1999. Pritzker KPH: Workshop on standardization of osteoarthritis histopathology, 4 th World Congress of the Osteoarthritis Research Society International, September 16-19, 1999, Vienna, Austria.* Pritzker KPH: Insulin-like growth factor effects on articular cartilage morphology and morphometry in model osteoarthritis. International Cartilage Repair Society, 3 rd Symposium, Gothenburg, Sweden, April 27-29, 2000. Baker RE, Gahunia HK, Vieth R, Pritzker KPH: A novel articular cartilage molecule: Time course of Dimethyldifuropyrone release from cartilage with acid hydrolysis. Sixth Canadian Connective Tissue Conference, Laval University, QuJbec City, QuJbec, May 25-27, 2000. Waddell JE, Pritzker KPH, Boynton EL: A comparison of the cytokine levels of failed total hip patients tonormal donors. Society for Biomaterials, Paper # 216, St. Paul, Minnesota, April 2001. Pritzker KPH: The Genetics Revolution - Implications for Medical Laboratory Technologists, College of Medical Laboratory Technologists of Ontario, Toronto, Ontario, April 5, 2001.* KPH Pritzker: Mark Adams: The Toronto Years. Mark Adams Memorial Lecture, Canadian Connective Tissue Conference, Mount Sinai Hospital, Toronto, May 25-26, 2001.* Pritzker KPH: Muscle pathology and rheumatic diseases. Teaching Sessions on Myositis and Myopathy, Sunnybrook and Women’s College Health Sciences Centre, September 26, 2001.* Pritzker KPH, Mullen B, Monga T, Hesse J: Some pathology applications requiring computer science. University of Toronto, Dept. of Communication Science, October 26, 2001.* Pritzker KPH: Medical and industrial models of laboratory service delivery, Insight Conference, The Old Mill, Toronto, December 11-12, 2001.* Waddell J, Pritzker KPH, Boynton EL: Inflammatory cytokine response to polyethylene particles in two patient populations. Orthopedic Research Society, Dallas, Texas, USA, February 9, 2002.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 375. Pritzker KPH: Osteoarthritis pathology: key research directions. First McCaig International Symposium on Joint Injury and Repair, University of Calgary, Department of Orthopedic Surgery, Emerald Lake, Alberta, March 23-24, 2002.*

Waddell JE, Pritzker KPH, Boynton EL: The use of cytokines as a predictive factor for elevated inflammatory responses. Society for Biomaterials, Tampa, Florida, April 2002. Pritzker KPH: General pathology of osteoarthritis. OA Consensus Conference, Toronto, April 2002.* La Scala GC, Yeung I, Mendes M, Addison PD, Eccles C, Guibord B, Marshall A, Scott S, Pritzker KPH, Pang CY, Neligan PC, Forrest CR: Hemodynamic and histopathologic investigation of the mechanism of radiation-induced craniofacial bone growth inhibition with and without cytoprotection in the infant New Zealand rabbit orbito-zygomatic complex (OZC). Plastic Surgery Research Council 47 th Annual Meeting, Boston, MA, April 17-20, 2002. Pritzker KPH: Pathogenesis of osteoarthritis: new perspectives. Osteoarthritis Consensus Conference, Toronto, Ontario, April 19-21, 2002.* Moridani MY, Pritzker KPH, Hoffman BR, Bromberg IL: Vitamin B12 absorption test in healthy human subjects. 53 rd Annual Meeting, Canadian Association of Pathologists, Calgary, Alberta, May 18- 23, 2002. La Scala GC, Yeung I, Leong I, Mendes M, Addison PD, Pritzker KPH, Pang CY, Neligan PC, Forrest CR: Hemodynamic and histopathologic investigation of the mechanism of radiation-induced craniofacial bone growth inhibition with and without cytoprotection in the infant New Zealand rabbit orbito- zygomatic complex (OZC). Canadian Society of Plastic Surgeons, Saint John, NB, June 12-25, 2002. Pritzker KPH: Calcium pyrophosphate dihydrate crystal arthropathy: a therapeutic challenge. Pfizer Research Laboratories, Groton, Connecticut, USA, July 24-25, 2002.* Pritzker KPH: Dimethyl-difuro-pyrone (DDP): an osteoarthritis biomarker? Pfizer Research Laboratories, Groton, Connecticut, USA, July 24-25, 2002.* Pritzker KPH: Clinical Laboratory Challenges 2007. 5 th Sysmex Scientific Seminar, Shanghai, China, September 6, 2002.* Pritzker KPH: Defining Osteoarthritis and Determining its Natural History. Canadian Arthritis Network, Calgary, Alberta, September 26, 2002.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 386. La Scala GC, Yeung I, Leong I, Mendes M, Addison PD, Pritzker KPH, Pang CY, Neligan PC, Forrest

CR: Hemodynamic and histopathologic investigation of the mechanism of radiation-induced craniofacial bone growth inhibition with and without cytoprotection in the infant New Zealand rabbit orbito- zygomatic complex (OZC). ASPS/PSEF/ASMS Scientific Meeting, San Antonio, Texas, November 3, 2002. Doria AS, Babyn PS, Crawley A, Noseworthy M, Pritzker KPH, Salter RB: Understanding the Functional Angiogenic Process in an Antigen-Induced Arthritis Model: Correlative BOLD MR Imaging (fMRI) of the Stages of Synovitis along the Time Course of the Disease. 45 th Annual Meeting of the Society for Pediatric Radiology, Philadelphia, PA, USA, 2002. Doria AS, Babyn PS, Crawley A, Noseworthy M, Pritzker KPH, Salter RB: Understanding the Functional Angiogenic Process in an Antigen-Induced Arthritis Model: Correlative BOLD MR Imaging (fMRI) of the Stages of Synovitis along the Time Course of the Disease. 10 th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, HA, USA, 2002. Kellenberger C, Doria AS, Babyn PS, Jong R, Pritzker KPH, Rogers M, Mendes M, Harasiewicz K, Holowka S, Mohanta A, Trayner T, Ancona M, Kharchakdjian R, Foster S, Burns P, Kent G, Salter R: New horizons in angiogenic-related imaging methods for characterization of the cause (synovitis) and consequence (cartilage degeneration) of arthritis in an antigen-induced experimental model: a linkage between anatomic and functional imaging. 39 th Annual Congress of the European Society of Paediatric Radiology, Bergen, Norway, 2002. Doria AS, Babyn PS, Crawley A, Noseworthy M, Pritzker K, Salter RB: Understanding the Functional Angiogenic Process in an Antigen-Induced Arthritis Model: Correlative BOLD MR Imaging (fMRI) of the Stages of Synovitis along the Time Course of the Disease. Caffey Award (Basic Science young Investigator Award at SPR 2002), 88 th Annual Meeting of the Radiological Society of North America, Chicago, IL, USA, 2002. Doria AS, Babyn PS, Harasiewicz K, Jong R, Pritzker KPH, Foster S: Ultrasound biomicroscopy for visualization of articular cartilage abnormalities of the knee in an antigen-induced arthritis model. 88 th Annual Meeting of the Radiological Society of North America,Chicago, IL, USA, 2002. Doria AS, Babyn PS, Harasiewicz KA, Rogers M, Foster S, Pritzker KPH: Ultrasound biomicroscopy for visualization of articular cartilage abnormalities of the knee in an antigen-induced arthritis model. Radiological Society of North America, December, 2002.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 393. Doria AS, Babyn PS, Mendes M, Jong ., Pritzker KPH, Foster FS: Articular Cartilage

Abnormalities of the Knee in an Antigen-Induced Arthritis Model: Diagnostic Efficacy of 40MHz Ultrasound Biomicroscopy (UBM). 45 th Annual Meeting of the Society for Pediatric Radiology, San Francisco, CA, USA, 2003. Doria AS, Babyn PS, Harasiewicz K, Rogers M, Jong R, Pritzker K, Foster FS: Ultrasound Biomicroscopy for Characterization of Articular Cartilage Abnormalities of the Knee in an Antigen-Induced Arthritis Model. 45 th Annual Meeting of the Society for Pediatric Radiology San Francisco, CA, USA, 2003. Doria AS, Babyn PS, Noseworthy M, Jong R, Mendes M, Pritzker KPH: Dynamic Contrast- Enhanced MRI (dMRI) Quantification of Synovium Microcirculation in Antigen-Induced Arthritis. 45 th Annual Meeting of the Society for Pediatric Radiology, San Francisco, CA, USA, 2003. Pritzker KPH: Regional Laboratory Service Planning. Vancouver Coastal Health Authority, Vancouver, BC, February 7, 2003.* Pritzker KPH: Preclinical Laboratory Services. Department of Pathology, University of Lausanne, Switzerland, May 19, 2003.* Pritzker KPH: SARS and the Single Hospital, Department of Pathology, University of Bern, Switzerland, May 20, 2003.* Pritzker KPH: Responding to the Unknown: SARS and the Hospital Laboratory. College of American Pathologists Conference 2003, San Diego, CA, September 14, 2003.* Pritzker KPH, Lavery S, Mendes MG: Histopathologic grading of experimental osteoarthritis. OARSI World Congress 2003, Berlin, Germany, October 12-15, 2003. Pritzker KPH: Bringing genomic markers to practice in clinical settings. Keystone Symposia, Genomic Biomarkers Impact on Drug Discovery and Clinical Practice (F1), Santa Fe, New Mexico, January 26-30, 2004.* Doria AS, Gahunia H, Jong R, Babyn P, Pritzker KPH, Foster FS: Multimodal imaging of cartilaginous lesions of the knee: comparison among macroscopy, MRI, US biomicroscopy (UBM) and histology. The Society of Pediatric Radiology Annual Meeting, Savannah, Georgia, April 28- May 1, 2004. Chiang LY, Pritzker KPH: Synthesis and biological effect of phenolic pyrrolinofullerene derivatives. 205 th Meeting of the Electrochemical Society, San Antonio, Texas, May 9-13, 2004.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 404. Yu C, Canteenwala T, Chiang LY, Pritzker KPH, Wilson BC: Evidence for singlet oxygen

generation from irradiated hydrophilic micelle-like hexa(sulfobutyl)fullerene (FC 4 S). Fullerene Symposium, Electrochemical Society Annual Meeting, San Antonio, Texas, May 10, 2004. So P, Pritzker KPH: Endogenous inhibitors of alkaline phosphatase and calcium pyrophosphate crystal deposition disease. (Poster) Canadian Connective Tissue Conference, St. Michael’s College, University of Toronto, Toronto, Canada, May 28-30, 2004. Chiang LY, Yu C, Canteenwala T, Halder M, Pritzker KPH, Wilson B: Photodynamic effect of hydrophilic C60=derived nanostructures for catalytic antibacteria/virus applications. ICMS 2004 Conference, Australia, 2003. Pritzker KPH: Spontaneous osteoarthritis in monkeys and man. International Program, National Institute of Arthritis, National Institutes of Health, Washington DC, June 23, 2004.* Chiang LY, Yu C, Canteenwala T, Halder M, Pritzker KPH, Wilson B: Photodynamic effect of hydrophilic C 60 -derived nanostructures for catalytic antibacterial/virus applications. International Conference of Science and Technology of Synthetic Metal 2004, Australia, July 2004. Johnson J-A, Hoffman B, Chitayat D, Winsor E, Pritzker KPH: First trimester screening (FTS) in the detection of down syndrome. SMFM 25th Annual Scientific Meeting 2004. Pritzker KPH: The future history of Canadian pathology. 55 th Annual Meeting of the Canadian Association of Pathologists, Montreal, Canada, July 3-7, 2004.* Sochett E, Makitie O, Doria AS, Mendes MG, Pritzker KPH: Bone histomorphometry in children with suspected secondary and idiopathic juvenile osteoporosis. Am Soc Bone Miner Res 26 th Annual Meeting, Seattle, Washington, USA, October 1-5, 2004. Chiang L, Hauck T, Pritzker KPH: Molecular self-assemblyof highly two-photon absorptive fullerene-diphenylaminofluorene dyads. Materials Research Society, Boston, Massachusetts, USA, November 30 December 4, 2004. Pritzker KPH, So P: Osteoarthritis and calcium pyrophosphate dihydrate crystal arthropathy. 9 th World Congress of the Osteoarthritis Research Society International, December 2-5, 2004. Mendes M, Rogers M, Pritzker KPH: Cartilage image analysis: preanalytical considerations. Image Analysis and In Vivo Pharmacology, Roskilde, Denmark, April 7-9, 2005.* Pritzker KPH, Mendes M: Osteoarthritic cartilage histologic features: image analysis criteria. Image Analysis and In Vivo Pharmacology, Roskilde, Denmark, April 7-9, 2005.*

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 416. Grynpas M, Makitie O, Pritzker KPH, Sochett E: The use of bone quality parameters in bone

biopsies of children with primary osteoporosis. Third International Conference on Children’s Bone Health, Sorrento, Italy, May 11-14, 2005. Chiang L, Pritzker KPH, Wilson B: Self-assembled amphiphilic two-photon absorptive diphenylaminofluorene-C60 vesicles for delivery. 207 th Meeting of the Electrochemical Society, Quebec City, Canada, May 15-20, 2005. So P, Pritzker KPH: Amino acids as endogenous inhibitors of alkaline phosphatase: implication for calcium pyrophosphate dihydrate crystaldeposition disease. Canadian Connective Tissue Conference, Montr al, Qu bec, May 27-28, 2005. Grynpas M, Makitie O, Pritzker KPH, Sochett E: Patterns of mineralization in children with secondary and syndrome associated osteoporosis. European Calcified Tissue Conference and International Bone and Mineral Society 2005, Geneva, Switzerland, June 25-29, 2005. Hauck TS, Padmawar PA, Canteenwala T, Pritzker KPH, Chiang LY: Characterization of chemically grafted carbon nanotubes by EELS spectroscopy. Photonics North, Toronto, Canada, Sept. 12-14, 2005. So G, Karotki A, Verma S, Hauck TS, Wilson B, Pritzker KPH, Chiang L: Singlet oxygen production by amphiphilic C60 derivatives and its correlation to cell cytotoxicity in vitro. Photonics North, Toronto, Canada, Sept. 12-14, 2005. Pritzker KPH: OARSI Osteoarthritis Cartilage Pathology Grading System: Development and Implementation. International Skeletal Society, Singapore, Sept. 28-Oct. 1, 2005.* Chiang L, Pritzker KPH, Wilson B: Two-photon absorption approach toward biophotonic application of amphiphilic fullerene-fluorene adducts. Symposium "Fullerenes and Carbon Nanotube Based Materials in Medicine and Biology" of the 209th Meeting of The Electrochemical Society, Adams Mark Denver Hotel, Denver, Colorado, May 7 - May 12, 2006. Pritzker KPH: Why animal models of osteoarthritis? CAN, International Conference on Preclinical Models of Osteoarthritis, Montreal, May 18-19, 2006. Pritzker KPH: Nonhuman primate models of osteoarthritis. CAN, International Conference on Preclinical Models of Osteoarthritis, Montreal, May 18-19, 2006.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 426. Las Heras F, Inman RD, Tsui F, Pritzker KPH: Chondrocyte morphology supports ank mice as an animal model for osteoarthritis (poster presentation). CAN, International Conference on

Preclinical Models of Osteoarthritis, Montreal, QC, May 18-19, 2006. Las Heras F, Pritzker KPH, Colgan TJ: Chordoma arising in a mature cystic teratoma of the ovary. 57 th Annual Meeting of the Canadian Association of Pathology, St. John’s, NL, July 15-19, 2006. (poster presentation) Las Heras F, Safir O, Gross AE, Pritzker KPHP: Cartilage transplantation pathology: features of graft failure and survival. 26 th Congress of the International Academy of Pathology, Montreal, QC, September 16-21, 2006. (poster presentation) Las Heras F, Inman R, Tsui F, Pritzker KPH: Ank/Ank mouse, an osteoarthritis model. 2006 World Congress on Osteoarthritis, December 7-10, 2006, Prague, Czech Republic. (podium presentation) Osteoarthritis and Cart 14(Suppl B 2006): pS147, December 2006. Gahunia HK, Doria AS, Babyn PS, Houpt JB, Pritzker KPH: Secondary osteonecroosis in the pediatric knee joints: radiologic characteristics. 2006 World Congress on Osteoarthritis, December 7-10, 2006, Prague, Czech Republic. (poster presentation) Osteoarthritis and Cart 14(Suppl B 2006): pS44, December 2006. Verma S, So G, Karotki A, Pritzker KPH, Wilson B, Chiang L: Biophotonic application of amphiphilic fullerene-fluorene adducts. 211 th Meeting of the Electrochemical Society, Chicago, Illinois, USA, May 6-10, 2007. (poster presentation) Las Heras F, Inman R, Tsui F, Pritzker KPH: Articular cartilage morphometrics: chondrocytes, matrix domains and calcification. Image Analysis and in vivo Pharmacology Meeting, Roskilde, Denmark, April 12-14, 2007. Las Heras F, Kim W, Kellett CF, Safir O, Backstein D, Gross AE, Pritzker KPH: Osteochondral allograft transplantation: histopathology of graft failure and survival. The Canadian Orthopaedic Association 62 nd Annual Meeting, Halifax, Nova Scotia, June 1-3, 2007. (poster presentation) Las Heras F, Inman RD, Tsui FL, Pritzker KPH: Cartilage hypertrophy: morphometric findings in an arthritis mouse model. Canadian Arthritis Network 2007 Annual Scientific Conference, Halifax, Nova Scotia, October 11-13, 2007. (poster presentation) Gross AE: Long-term results of fresh osteochondral allografts for posttraumatic knee defects. Musculoskeletal Transplant Foundation Fifth International Symposium, Vancouver, British Columbia, October 11-13, 2007.

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Dr. K.P.H. Pritzker SCHOLARLY ADDRESSES 436. Las Heras F, Inman RD, Tsui F, Pritzker KPH: Chondrocyte hypertrophy in ank-/ank- mice:

implications for osteoarthritis. OARSI World Congress on Osteoarthritis 2007, Fort Lauderdale, Florida, December 6-9, 2007. Las Heras F, Bubbar V, Amato D, Gross AE, Pritzker KPH: Gaucher disease: bone histomorphology after enzyme replacement therapy. USCAP 97 th Annual Meeting, Denver, Colorado, March 1-7, 2008. Bahrami A, Haaland DA, Churchill DN, Pritzker KPH, Adachi JD: Oncogenic osteomalacia: a case report and review of the literature. Canadian Rheumatology Association Annual Meeting and Workshop, Mont Tremblant, Quebec, March 5-8, 2008. Nussbaum EL, Mazzulli T, Pritzker KPHP, Las Heras F, Lilge L: Effects of low intensity laser light on wound healing in the rat. 2008 Biomedical Optics (BIOMED) Topical Meeting, Hilton St. Petersburg Bayfront, St. Petersburg, Florida, USA, March 16-19, 2008.* Biessels P, Mudumba S, Kahama A, Ding S-F, Ling M, Lea P, Wang S, Azad A, Pritzker K, Keystone E. A novel anti-citrullinated peptide antibody assay using a four-analyte multiplexed QuantiSpot rheumatoid arthritis test system. The Oak Ridge Conference, Oak Ridge, California, USA, April 17, 2008. Pritzker KPH, Las Heras F, Bubar V, Amato D, Gross AE: Gaucher Disease: Bone histomorphology after ERT. LSD Club 2008, Genzyme Canada, Metropolitan Hotel, Toronto, May 1, 2008 Gross AE, Kim W, Las Heras F, Backstein D, Safir O, Pritzker KPH: Fresh osteochondral allografts for posttraumatic knee defects: long-term follow-up. Combined Meeting of the American Orthopaedic Association and the Canadian Orthopaedic Association, Quebec City, June 4-7, 2008. (podium presentation)*

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Dr. K.P.H. Pritzker * Invited

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Dr. K.P.H. Pritzker PUBLICATIONS 1. 2. Pritzker KPH: Tumor antigens. University of Toronto Medical Journal 42:151-153, February 1965.

Pritzker KPH: Medical education: the legacy of Abraham Flexner. University of Toronto Medical Journal 44:224-226, April 1967. Johnson GE, Pritzker KPH: The influence of the dopa decarboxylase inhibitor Ro-4-4602 on the urinary excretion of catecholamines in cold-stressed rats. Journal of Pharmacology and Experimental Therapeutics 152:432-438, 1966. Pritzker KPH, Huang SN, Marshall KG: Malignant tumors following immunosuppressive therapy. Canadian Medical Association Journal 103: 1362-1365, 1970. Pritzker KPH, Suh A, Huang SN: Neoplasia in renal transplant recipients. Letter to Editor, C.M.A.J. 107:1059-1062, 1972. Kahn DS, Pritzker KPH: The pathophysiology of bone infection. Clinical Orthopedics and Related Research 96:12-19, 1973. Langer F, Czitrom A, Gross A, Langer F, Pritzker KPH: The immunogenicity of fresh and frozen allogeneic bone. Journal of Bone and Joint Surgery 57A:216-220, 1975. Koven IH, Stubbs R, Pritzker KPH, Liswood A, Lo S: Interstitial tissue barrier during low flow: its correction by Hyaluronidase. Proceedings of the First World Congress for Microcirculation, Toronto, June 1975. Plenum Press 1975. KPH Pritzker: Committee on Physician Manpower. Manpower requirements - anatomical pathology. Report of the Working Party in Pathology to the Requirements. Ministry of National Health and Welfare, 1976. Pritzker KPH, Luk SC: Apatite associated arthropathies: preliminary ultrastructural studies. Scanning Electron Microscopy 493-500, 1976. Pritzker KPH, Phillips H, Luk SC, Koven IH, Kiss A, Houpt JB: Pseudotumor of temporomandibular joint: destructive calcium pyrophosphate dihydrate arthropathy. Journal of Rheumatology 3(1):70-81, 1976. Czitrom A, Pritzker KPH, Langer F, Gross AE, Luk SC: Virus-induced osteosarcoma in rats. Journal of Bone and Joint Surgery 58A:303-308, 1976.

3. 4. 5. 6. 7. 8. 9. 10. 11. 12.

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Dr. K.P.H. Pritzker PUBLICATIONS 13. Urowitz EP, Czitrom A, Langer F, Gross AE, Pritzker KPH: Immunogenicity of virus-induced rat osteosarcoma. Journal of Bone and Joint Surgery 58A:308-311, 1976.

Rosen PS, Pritzker KPH, Greenbaum J, Holgate RC, Noyek AM: Synovial chondromatosis affecting the temporomandibular joint. Arthritis and Rheumatism 20:736-740, 1976. Noyek AM, Holgate RC, Fireman SM, Rosen PS, Pritzker KPH: The radiologic findings in synovial chondromatosis (chondrometaplasia) of the temporomandibular joint. Journal of Otolaryngology 6(3):45-48, 1977. Kovacs K, Horvath E, Pritzker KPH, Schwartz ML: Pituitary growth hormone cell adenoma with cytoplasmic tubular aggregates in the capillary endothelium. Acta Neuropathologica 37:77-79, 1977. Pritzker KPH: Aging and degeneration in the lumbar intervertebral disc. Orthopaedic Clinics of North America 8(1):65-77, Jan. 1977. Bruni J, Bilbao JM, Pritzker KPH: Myopathy associated with amyloid angiopathy. Canadian Journal of Neurological Sciences 77-80, February 1977. Pritzker KPH, Gross AE, Langer F, Luk SC, Houpt JB: Articular cartilage transplantation. Human Pathology 8(6):635-651, Nov. 1977. Bruni J, Bilbao JM, Pritzker KPH: Vascular amyloid in the aging central nervous system. Canadian Journal of Neurological Sciences 4:239-244, 1977. Pritzker KPH, Zahn CF, Nyburg SC, Luk SC, Houpt JB: The ultrastructure of urate crystals in gout. Journal of Rheumatology 5:7-28, 1978. Goldberg M, Noyek AM, Pritzker KPH: Laryngeal granuloma secondary to gastro-esophageal reflux. Journal of Otolaryngology 7:196-202, 1978. Trokoudes KM, Walfish PG, Holgate RC, Pritzker KPH, Schwartz ML, Kovacs K: Sellar enlargement with hyperprolactinemia and a Rathke’s pouch cyst. Journal of the American Medical Association 240:471-473, 1978. Pritzker KPH, Cheng P-T, Adams ME, Nyburg SC: Calcium pyrophosphate dihydrate crystal formation in model hydrogels. Journal of Rheumatology 5(4):469-473, 1978. Postnikoff IM, Pritzker KPH: Hereditary angioneurotic edema: an unusual case of maternal mortality. Journal of Forensic Sciences 2:473-478, 1979.

14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25.

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Dr. K.P.H. Pritzker PUBLICATIONS 26. Fam AG, Pritzker KPH, Stein JL, Houpt JB, Little AH: Apatite-associated arthropathy: a clinical study

of 14 cases and of 2 patients with calcific bursitis. Journal of Rheumatology 16:461-471, 1979. Cheng P-T, Nyburg SC, Adams ME, Pritzker KPH: Beta-calcium disodium pyrophosphate tetrahydrate. Crystal Structure Communications 8:313-317, 1979. Halloran PF, Ziv I, Lee EH, Langer F, Pritzker KPH, Gross AE: Orthotopic bone transplantation in mice: 1. Technique and assessment of healing. Transplantation 27:414-419, 1979. Omar SA, Cheng P-T, Nyburg SC, Pritzker KPH: Application of scanning and transmission electron microscopy, x-ray energy spectroscopy and x-ray diffraction to calcium pyrophosphate crystal formation in vitro. Scanning Electron Microscopy 645-750, 1979. Cheng P-T, Pritzker KPH, Adams ME, Nyburg SC, Omar SA: Calcium pyrophosphate dihydrate crystal formation in aqueous solutions. Journal of Rheumatology 7(5):609-616, 1980. Pritzker KPH, Adams ME, Cheng P-T, Omar SA, Cruickshank B: Black synovium: a consequence of intraarticular gold therapy. Arthritis and Rheumatism 23:496-504, 1980. Czitrom A, Pritzker KPH: Simple bone cyst causing collapse of the articular surface of the femoral head and incongruity of the hip joint - a case report. Journal of Bone and Joint Surgery 62A:842-845, 1980. Vozis EE, Pritzker KPH: Pancreatic islet cell tumour of childhood. Canadian Medical Association Journal 122:435-438, 1980. Lambert JR, Luk SC, Pritzker KPH: Brown bowel syndrome in Crohn’s Disease. Archives of Pathology and Laboratory Medicine 104:201-205, 1980. Pritzker KPH: Pathogenesis de la gota y la pseudogota (The pathogenesis of gout and pseudogout). Seminarios de Reumatologia, Ediciones Lerner, 1980 Bogata, Capitulo 8:83-93. Noyek AM, Pritzker KPH, Greyson ND: Familial Warthin’s tumour: 1. Its synchronous occurrence in mother and son. 2. Its association with cystic oncocytic metaplasia of the larynx. Journal of Otolaryngology 9:90-96, 1980. Cheng P-T, Pritzker KPH, Nyburg SC: Alpha calcium disodium pyrophosphate tetrahydrate. Acta Crystallographica 36(B):921-924, 1980

27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37.

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Dr. K.P.H. Pritzker PUBLICATIONS 38. Pritzker KPH: Crystal-associated arthropathies: what’s new in old joints. Journal of American

Geriatric Society 28:439-445, 1980. Fam AG, Pritzker KPH, Little AH, Cheng P-T: Cholesterol crystals in osteoarthritic joint effusions. Journal of Rheumatology 8:273-280, 1981. Pritzker KPH, Desai SD, Patterson MC, Cheng P-T: Calcite sputum lith. American Journal of Clinical Pathology 75:253-257, 1982 Czitrom AZ, Langer F, Gross AE, Urovitz EP, Pritzker KPH: The biology, pathology and immunology of a virus induced rat osteosarcoma. I. Biological behaviour and histopathology. International Orthopaedics (SICOT) 4:157-165, 1980. Czitrom AA, Langer F, Gross AE, Urovitz EP, Pritzker KPH: The biology, pathology and immunology of a virus induced rat osteosarcoma. II. Immunological studies. International Ortopaedics (SICOT) 4:167-175, 1980. Pritzker KPH, Cheng P-T, Omar SA, Nyburg SC: Calcium pyrophosphate crystal formation in model hydrogels. II. Hyaline Articular Cartilage as a Gel. Journal of Rheumatology 8(3):451-455, 1981. Srigley J, Lambert CD, Bilbao JM, Pritzker KPH: Spinal cord infarction secondary to intervertebral disc embolism. Annals of Neurology 9:296-301, 1981. Pritzker KPH, Fam AG, Omar SA, Gertzbein SD: Experimental cholesterol crystal arthropathy. Journal of Rheumatology 8:281-290, 1981. Cheng P-T, Pritzker KPH. Effect of heat on crystals. Arthritis and Rheumatism 24:637-638, 1981. Kandel RA, Pritzker KPH, Bedard YC: Symmetrical fibro-osseous dysplasia of rib - post-traumatic dysplasia? Histopathology 5:651-658, 1981. Cheng P-T, Pritzker KPH: The effect of calcium and magnesium ions on calcium pyrophosphate crystal formation in aqueous solutions. Journal of Rheumatology 8(5):772-782, 1981. Tenenbaum J, Pritzker KPH, Gross AE, Cheng P-T, Renlund RC: The effects of intraarticular corticosteroids in articular cartilage. Seminars in Arthritis and Rheumatism 9(supplement 1):140-141, 1981. Cheng P-T, Pritzker KPH, Tausch J, Pittaway A, Millard J. Analytical scanning electron microscopy and x-ray microdiffractometry of renal calculi using etched plastic sections. Scanning Electron Microscopy/1981, III:163-168, 1981.

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Dr. K.P.H. Pritzker PUBLICATIONS 51. Wilkinson S, Houpt JB, Pritzker KPH, Gross AE: Avulsion of quadriceps tendons in a patient with an

unusual deforming arthritis and varied skin lesions. Journal of Rheumatology 8:983-988, 1981. Freeman JL, Shemen JL, Alberti PW, Holgate R, Pritzker KPH, Noyek AM: Ossifying capillary hemangioma of the maxillary and ethmoid sinuses. A case report. Journal of Otolaryngology 10:481-492, 1981. Pritzker KPH: Crystals in human disease - the state of the art. Journal of Rheumatology 8(6):1000-1003, 1981. Kandel RA, Pritzker KPH, Bilbao JM, Gordon AS: Extramedullary haematopoiesis simulating parasagittal meningioma. Canadian Journal of Neurological Sciences 9:49-51, 1982. Lotem M, Alpert B, Houpt JB, Greyson ND, Pritzker KPH, Langer F, Gross AE: Spontaneous osteonecrosis of the medial tibial plateau. Journal of Rheumatology 9:81-90, 1982. Langer F, Pritzker KPH, Gross AE, Shapiro II: Giant cell tumour associated with trauma. Clin. Orthop. 164:245-248, 1982. Pritzker KPH, Renlund RC, Read DH, Cheng P-T, Harrington DD. Adrenal and hepatic calcium stearate crystal deposits in dogs fed a thiamine deficient diet. Am. Journal of Veterinary Research 43:1481-1488, 1982. Rubin L, Pritzker KPH, Cheng P-T, Fam A: Multiple-crystal acute polyarthritis. Annals of the Rheumatic Diseases 42(2):213-215, 1983. Renlund RC, Kandel RA, Cheng P-T, Rapley WA, Mehren KG, Pritzker, KPH: Calcium pyrophosphate dihydrate crystal deposition disease with concurrent vertebral hyperostosis in a barbary ape. Arthritis and Rheumatism 26(5):682-687, 1983. Gross AE, McKee NH, Pritzker KPH, Langer F: Reconstruction of skeletal deficits at the knee - a comprehensive osteochondral transplant program. Clinical Orthopaedics 174:96-106, 1983. Reid AD, Cheng P-T, Grynpas MD, Pritzker KPH: Application of electron diffraction to crystal identification of pathologic tissue. Proceed. of Microscopical Society of Canada 54-55, 1983. Pritzker KPH, Renlund RC, Cheng P-T. Which comes first - crystals or osteoarthritis? A study of surgically removed femoral heads. J Rheumatol Suppl 9:38-39, 1983. Pritzker KPH: Which comes first - osteonecrosis or osteoarthritis? J Rheumatol Suppl 9:53-54, 1983. Cheng P-T, Pritzker KPH: Solution Ca/P ratio affects calcium phosphate crystal phases. Calcified Tissue International 35(4-5):596-601, 1983.

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Dr. K.P.H. Pritzker PUBLICATIONS 65. Cheng P-T, Pritzker KPH, Kandel RA, Reid A: Analytical scanning and transmission electron

microscopy and x-ray microdiffractometry of calcium pyrophosphate dihydrate crystal deposits in tissues. Scanning Electron Microscopy 369-377, 1983. Lipson RA, Kawano H, Halloran PF, McKee NH, Pritzker KPH, Langer F: Vascularized limb transplantation in the rat. I. Results with syngeneic grafts. Transplantation 35(4):293-299, 1983. Lipson RA, Kawano H, Halloran PF, Pritzker KPH, Langer F: Vascularized limb transplantation in the rat. II. Results with allogeneic grafts. Transplantation 35(4):300-304, 1983. Kliman ME, Gross AE, Pritzker KPH, Greyson ND: Osteochondritis of the hallux sesamoid bones. Foot and Ankle 3(Jan-Feb), 1983. Cheng P-T, Pritzker KPH: Pyrophosphate, phosphate ion interaction: effects on calcium pyrophosphate and hydroxyapatite crystal formation in aqueous solutions. Journal of Rheumatology 10(5):769-777, 1983. Houpt JB, Pritzker KPH, Alpert B, Greyson MD, Gross AE: Natural history of spontaneous osteonecrosis of the knee - a review. Seminars in Arthritis and Rheumatism 13(2):212-227, Nov. 1983. Pritzker KPH: Clinical manifestations of calcium pyrophosphate dihydrate crystal deposition disease. Geriatric Med Today 2:101-108, 1983. Cheng P-T, Reid A, Millard J, Pritzker KPH, Khanna R, Oreopoulos DG: Ultrastructural studies of renal stones from patients on continuous ambulatory peritoneal dialysis. Scanning Electron Microscopy 4IV:1939-1946, 1983. Saldanha CF, Deitel M, Thompson DA, Patterson MC and Pritzker KPH: Pink urine in morbidly obese patients following operation. American Surgical Forum XXXIV:175-178, 1983. Cheng P-T, Pritzker KPH, Oreopoulos DR: Heterogeneity of renal stones from patients on peritoneal dialysis.IN: Urinary Stone Proceedings of IInd International Conference on Urinary Stones, Singapore, February 9, 1983, Churchill-Livingston pp. 318-323, 1984. Kandel RA, B dard YC, Pritzker KPH, Luk SC: Lymphoma - presenting as an intramuscular small cell malignant tumour. Cancer 53(7):1586-1589, 1984. Kandel RA, Pritzker KPH, Langer F, Gross AE: The pathologic features of massive osseous grafts. Human Pathology 15(2):141-146, Feb. 1984.

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Dr. K.P.H. Pritzker PUBLICATIONS 77. Deitel M, Thompson DA, Saldanha CF, Ramshaw PJ, Patterson MC, Pritzker KPH: "Pink Urine" in

morbidly obese patients following gastric partitioning. Canadian Medical Association Journal 13(8):1007-1011, 1984. Renlund RC and Pritzker KPH: Malignant fibrous histiocytoma involving the digit in a cat. Veterinary Pathology 21(4):442-444, 1984. Reid AD, Grynpas MD, Pritzker KPH and Harrison JE: Structural changes induced by fluoride in rat bones. Proceedings of Electron Microscopy Society of America 718-719, 1984. Peters WJ, Kaddourah I and Pritzker KPH: Massive soft tissue chondroma of the hand. Annals of Plastic Surgery 14(6):545-547, 1985. Tepperman PS, Hilbert L, Peters WJ, Pritzker KPH: Heterotopic ossification in burns. Journal of Burn Care and Rehabilitation 5:283-287, 1985. Peters WJ and Pritzker KPH: Massive heterotopic ossification in breast implant capsules. Aesthetic Plastic Surgery 9(1):43-45, 1985. Cheng P-T, Reid AD and Pritzker KPH: Ultrastructural studies of crystal-organic matrix relations in renal stones. Scanning Electron Microscopy I:201-207, 1985. Grynpas MD, Landis WJ and Pritzker KPH: Milk of calcium: a structural study. Scanning Electron Microscopy IV:1765-1770, 1984. Hogan DB and Pritzker KPH: Synovial fluid analysis - another look at the mucin clot test. Journal of Rheumatology 12(2):242-244, 1985. Hunter GK, Rogakou CC and Pritzker KPH: Extracellular matrix synthesis by articular chondrocytes and synovial fibroblasts in long-term monolayer culture. Biochemica et Biophysica Acta 804(4):459-465, 1984. Pritzker KPH, Cheng P-T, Hunter GK, Grynpas MD, Kessler MJ and Renlund RC: In vitro and in vivo models of calcium pyrophosphate crystal formation. Chemistry and Biology of Mineralized Tissues, Ed. W.T. Butler, Ebsco Media Inc., Birmingham, Alabama, USA, pp. 381-384, 1985. Cheng P-T, Di Gregorio RC, Holmyard DP and Pritzker KPH: Minimization of calcium phosphate loss during aqueous processing by saturating aqueous reagents with hydroxyapatite. Proceedings of Microscopical Society of Canada 66-67, 1985.

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Dr. K.P.H. Pritzker PUBLICATIONS 89. Cheng P-T and Pritzker KPH: Alternating crystallization - a proposed mechanism for lamellar

structure formation in renal stones. Urolithiasis and Related Research, Plenum Publishing Corp. Ed. P.O. Schwille, E.H. Smith, 919-222, 1985. McDermott AGP, Langer F, Pritzker KPH, Gross AE: Fresh small-fragment osteochondral allografts: long term follow-up study on the first 100 cases. Clinical Orthop & Rel Res 197:96-102, 1985. Kandel RA, Gross AE, Ganel A, McDermott AGP, Langer F, Pritzker KPH: Histopathology of failed osteoarticular shell allografts. Clin Orthop & Rel Res 197:103-110, 1985. Bayne O, Langer F, Pritzker KPH, Houpt J, Gross AE: Osteochondral allografts in the treatment of osteonecrosis of the knee. Orthop Clinics of NA 16(4):727-740, 1985. Gross AE, Langer F, McKee W, Czitrom A and Pritzker KPH: A comprehensive orthopedic transplant unit. Transplantation Today 2:38-44, 1985 and Greffes de l’appareil locomoteur, eds Dominique Poitout et al, Masson, Paris, 127-131, January 1987. Buckspan MB, Skeldon SC, Klotz PG and Pritzker KPH: Epidermoid cysts of the testicle. J of Urology 134(5):960, 1986. Egerdie RB, Buckspan MB, Klotz PG, Steinhardt MI, Pritzker KPH: Bilateral multilocular renal cysts. J Urol 135(2):346-348, February 1986. Kessler MJ, Turnquist JE, Pritzker KPH, London WT: Reduction of passive extension and radiographic evidence of degenerative knee joint diseases in cage-raised and free-ranging aged Rhesus monkeys (Macaca Mulatta) J Medical Primatology 15(1):1-10, 1986. Renlund RC, Pritzker KPH, Kessler MJ: Rhesus monkey (Macaca Mulatta) as a model for calcium pyrophosphate dihydrate crystal deposition disease. J Medical Primatology 15(1):11-16, 1986. Kandel RA, Cheng P-T, Pritzker KPH: Localized apatite synovitis of the wrist. J of Rheumatology 13:667-669, 1986. Pritzker KPH: Calcium pyrophosphate crystal arthropathy: a biomineralization disorder. Human Pathology 17(6):543-545, June 1986. Tenenbaum HC, Holmyard D, Palangio K, Pritzker KPH: An ultrastructural study of bone formation in vitro. In: Cell Mediated Calcification and Matrix Vesicles, ed. Yousuf Ali, Elsevier Science, p. 321, 1986.

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Dr. K.P.H. Pritzker PUBLICATIONS 101. Tenenbaum HC, Palangio KG, Holmyard DP, Pritzker KPH: An ultrastructural study of osteogenesis

in chick periosteum in vitro. Bone 7(4):295-302, 1986. Grynpas MD, Simmons ED, Pritzker KPH, Hancock RV, Harrison JE: Is fluoridated bone different from non-fluoridated bone. In: Cell mediated calcification and matrix vesicles, Ed. by Y. Ali, Elsevier Science, 409-414, 1986. Kandel RA, Cheng P-T, Pritzker KPH: Localized apatite synovitis of the wrist. J of Rheumatology, 13(3):667-669, 1986. Hunter GK, Nyburg SC, Pritzker KPH: Hydroxyapatite formation in collagen gelatin and agarose gels. Collagen and Related Research 6(3):229-238, 1986. McDermott AGP, Langer F, Pritzker KPH, Gross AE: Fresh small-fragment osteochondral allografts: long term follow-up study on the first 100 cases. 1986 Year Book of Orthopaedics, 176- 178, November, 1986. Pritzker KPH, Ch teauvert JD, Grynpas MF: Osteoarthritic cartilage contains increased calcium, magnesium and phosphorus. J of Rheumatol 14(4):806-810, 1987. Hunter GK, Grynpas MD, Cheng P-T and Pritzker KPH: Effect of glycosaminoglycans on calcium pyrophosphate crystal formation in collagen gels. Calc Tiss Int. 41(3):164-170, 1987. Oakeshott RD, Farine I, Pritzker KPH, Langer F, Gross AEA: A clinical and histological analysis of failed fresh osteochondral allografts. J Bone and Joint Surgery (British Volume) 69(B):502-508, May 1987. Grynpas MD, Pritzker KPH, Hancock RGV: Neutron activation analysis of bulk and selected trace elements in bones using a low flux slowpoke reactor. Biological Trace Elements Research, 13:333- 334, 1987. Cheng P-T, Pritzker KPH, Richards J, Holmyard D: Fictitious calculi and human calculi with foreign nuclei. Scanning Microscopy 1(4):2025-2032, 1987. Grynpas MD, Cheng P-T, Pritzker KPH: Dissolution of calcium pyrophosphate crystals by free radicals generated by neutron irradiation. J. Rheumatol 14(5):1073-1074, 1987. Grynpas MD, Katz I, Pritzker KPH: Bone quality and bone quantity in osteoporosis. In: "Osteoporosis 87" ed. by C. Christiansen, J.S. Johansen, B.J. Riis, Osteopress, Copenhagen, 1:364- 366, 1987.

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Dr. K.P.H. Pritzker PUBLICATIONS 113. Bayley TA, Harrison JE, Josse RG, Murray TM, Sturtridge W, Williams C, Patt N, Goodwin S,

Pritzker KPH, Fornasier V: The relationships between fluoride effects on bone histology, bone mass and bone strength. In: "Osteoporosis 87"ed. by C. Christiansen, J.S. Johansen, B.J. Riis, Osteopress, Copenhagen, 2:865-867, 1987. Vieth R, Kessler MJ, Pritzker KPH: Serum concentrations of vitamin D metabolites in Cayo Santiago Rhesus Macaques. American J Med Primatol. 16:349-357, 1987. Cheng P-T, Pritzker KPH: Inhibition of calcium pyrophosphate dihydrate crystal formation: effects of carboxylate ions. Calcified Tissue International 42(1):46-52, 1988. Pritzker KPH, Cheng P-T, Renlund RC: Calcium pyrophosphate crystal deposition in hyaline cartilage. Ultrastructural analysis and implications for pathogenesis. Journal of Rheumatology 15(5):828-835, 1988. Cheng P-T, Pritzker KPH: Ferrous (Fe++) but not ferric (Fe+++) ions inhibit de novo formation of calcium pyrophosphate dihydrate crystals: Possible relationships to chondrocalcinosis and hemochromatosis. Journal of Rheumatology 15(2):321-324, 1988. Grynpas MD, Simmons ED, Carnes D, Gundberg C, Pritzker KPH: Bone mineral in the castrated rat model of osteopenia. Journal of Orthopaedic Research 5(4):586-591, 1988. Pritzker KPH, Cheng P-T, Grynpas MD, Holmyard D: Crystal associated diseases: the role of scanning electron microscopy in diagnosis. Scanning Microscopy 2(3):1471-1478, 1988. Cheng P-T, DiGregorio RC, Li F, Pritzker KPH: Analytical and ultrastructural studies of dietary nephrocalcinosis in rats. Proceedings of 4th Asia-Pacific Conference and Workshop on Electron Microscopy, Bangkok, APEM: 741-746, 1988. Walfish PG, Pollard A, Pritzker KPH: Diagnosing and managing hyperparathyroidism: exclude other causes of hypercalcemia. Diagnosis 5:77-109, October 1988. Rubenstein JD, Pritzker: Crystal associated arthropathies. Amer J Radiol 152(4):685-695, 1989. Grynpas MD, Huckell B, Pritzker KPH, Hancock RGV and Kessler, MJ: Bone mineral and osteoporosis in aging Rhesus monkeys. Puerto Rico Health Sciences J 8(1):197-204, 1989. Hancock RGV, Grynpas MD and Pritzker KPH: The abuse of bone analyses for archaeological dietary studies. Archaeometry 31(2):169-179, 1989. Pritzker KPH, Chateauvert J, Grynpas M, Renlund R, Turnquist J and Kessler MJ: Rhesus Macaques as an experimental model for degenerative arthritis. Puerto Rico J Health Sciences 8(1):99-102, 1989.

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Dr. K.P.H. Pritzker PUBLICATIONS 126. Keating, SJ, Eyre DR, Pritzker KPH: Short rib polydactyly syndrome type I: An autopsy approach to

diagnosis of chondrodysplasias. Modern Pathology 2(5):427-432, 1989. Chateauvert JMD, Pritzker, KPH, Kessler MJ, Grynpas MD: Spontaneous osteoarthritis in rhesus macaques. I. Chemical and biochemical studies. J. Rheumatology 16(8):1098-1104, 1989. Chateauvert JMD, Grynpas MD, Kessler MJ, Pritzker, KPH: Spontaneous osteoarthritis in rhesus macaques: II. Characterization of disease and morphometric studies. J. Rheumatology 17(1):73-83, 1990. Lambert RGW, Becker EJ, Pritzker KPH: Tumoral calcium pyrophosphate dihydrate crystal arthropathy affecting temporomandibular joint. Skeletal Radiol 19:139-141, 1990. Murray TM, Harrison JE, Bayley TA, Josse RG, Sturtridge WC, Chow R, Budden F, Laurier L, Pritzker KPH, Kandel R, Vieth R, Strauss A and Goodwin S: Fluoride treatment of postmenopausal osteoporosis. Age, renal function and other clinical factors in the osteogenic response. J Bone and Mineral Res 5(suppl. 1):S27-35, March, 1990. Bayley TA, Muller C, Harrison J, Basualdo J, Sturtridge W, Josse R, Murray TM, Pritzker KPH, Vieth R, Goodwin S, Strauss A: The long-term treatment of steroid osteoporosis with fluoride. J Bone and Mineral Res 5(suppl. 1):S157-61, March, 1990. Bayley TA, Harrison JE, Murray TM, Josse RG, Sturtridge W, Pritzker KPH, Strauss A, Vieth R, Goodwin S: Fluoride-induced fractures: relation to osteogenic effect. J Bone and Mineral Res 5(suppl. 1):S217-22, March, 1990. Vieth R, Kessler MJ, Pritzker KPH: Species differences in the binding kinetics of 25-hydroxyvitamin D 3 to vitamin D binding protein. Canadian J Physiol & Pharmacol 68(10):1368-71, October 1990. Cruz TF, Mills G, Pritzker KPH, Kandel RA: Inverse correlation between tyrosine phosphorylation and collagenase production by chondrocytes. Biochem J 269(3):717-21, 1990. Kandel RA, Petilycky M, Dinarello C, Minden M, Pritzker KPH and Cruz TF: Comparison of the effect of Interleukin 6 and Interleukin 1 on collagenase and proteoglycan production by chondrocytes. J Rheumatol 17(7):953-57, 1990.

Kandel RA, Pritzker KPH, Mills G, Cruz TF: Fetal bovine serum inhibits chondrocyte collagenase production: interleukin 1 reverses this effect. Biochem Biophys Acta 1053(2-3):130-34, 1990. Tornos C, Silva, El-Naggar A, Pritzker KPH: Calcium oxalate crystals in breast biopsies: the missing microcalcifications. Amer J Surg Pathol 14(10):961-968, 1990.

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Dr. K.P.H. Pritzker PUBLICATIONS 138. Keating SJ and Pritzker KPH: The source of lysozyme in chick embryo cartilage. Methods in Cartilage Research. Section 8, 49:194-196, 1990.

Grynpas MD, Chateauvert JMD, Pritzker KPH: Determining the elemental composition of articular cartilage: a comparison between human and non-human primates. Methods in Cartilage Research. Section 10, 60:248-251, 1990. Pritzker KPH, Chateauvert J, Grynpas MD, Kessler MJ: Studies of naturally occurring degenerative arthritis in Rhesus Macaques as a model for degenerative arthritis in man. Methods in Cartilage Research. Section 13, 78:341-342, 1990. Xu Y, Cruz T, Cheng P-T, Pritzker KPH: Effects of pyrophosphatase on dissolution of calcium pyrophosphate dihydrate (CPPD) crystals. J Rheumatol 18(1):66-71, 1991. Simmons Jr. ED, Pritzker KPH, Grynpas MD: Age-related changes in the human femoral cortex. J Orthopaedic Res Soc 9(2):155-167, 1991. Pritzker, KPH: Posttraumatic cartilage hypertrophy: edema or repair? Editorial. J Rheumatol 18(3):314-315, 1991. Fam AG, Schumacher Jr MD, Pritzker KPH: Crystal-induced arthritis. Royal College of Physicians & Surgeons Annals 24(5):321-322, 1991. Grynpas MD, Pritzker KPH, Very JM, Mertz B. (1990) Changes in mineralization profiles due to long term administration of APD in the dog. In: "Osteoporosis 90" ed. by C. Christiansen, Osteopress, Copenhagen, 1358-1360, 1991. Grynpas MD, Alpert I, Katz I, Lieberman I, Pritzker KPH: Subchondral bone in osteoarthritis. Calcified Tissue International 49(1):20-26, 1991. Xu Y, Cruz TF, Pritzker KPH: Alkaline phosphatase dissolves calcium pyrophosphate dihydrate crystals. J Rheumatol 18(10):1606-1610, 1991. Fam AG, Schumacher HR Jr, Clayburne G, Sieck M, Mandel NS, Cheng P-T, Pritzker KPH: A comparison of five preparations of synthetic monosodium urate monohydrate (MSUM) crystals. J Rheumatol 19(5):780-787, 1992. Fam AG, Pritzker KPH: Acute calcific periarthritis in scleroderma. J Rheumatol 19(10):1580-85, 1992. Howarth D, Pritzker KPH, Cruz TF, Kandel RA: Calcium ionophore A23187 stimulates production of a 144 kDa gelatinase. J Rheumatol 20(1):97-101, 1993.

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Dr. K.P.H. Pritzker PUBLICATIONS 151. Mendes M, Pritzker KPH: Optimizing multiple fluorochrome bone histodynamic markers. Bone 14(3):537-543, 1993.

Hunter GK, Holmyard DP, Pritzker KPH: Calcification of chick vertebral chondrocytes grown in agarose gels: a biochemical and ultrastructural study. J Cell Science 104(Pt 4):1031-1038, 1993. Pritzker KPH: Crystal formation and dissolution. Revista Espanola de Reumatologia 20(Suppl 1):97- 98, 1993. Pritzker KPH: Calcium pyrophosphate crystal formation, deposition, and dissolution. Revista Espanola de Reumatologia 20(Suppl 1):244, 1993. Mass PG, Weiser H, Pritkzer KPH: Effects of modifying dietary protein in the presence and absence of vitamin B 6 , on the regulation of plasma calcium and phosphorus levels - positive impact of yeast Saccharomyces Cerevisiae. Internat. J. Vit. Nutr. Res. 63(1):47-55, 1993. Pritzker KPH: Intra-osseous Thrombosis in Osteoarthritis: Association or Causation? Osteoarthritis and Cartilage 1:207-208, 1993. Fernandes BJ, Abbott D, Pritzker KPH, Musclow E, Ray P, Atkinson J: Advanced Laboratory Systemization Utilizing the HS-302 TM . Sysmex Journal International 3(2): 154-159, 1993. Harasiewicz KA, Kim HKW, Babyn PS, Pritzker KPH, Foster FS: Ultrasound backscatter microscopy of articular cartilage in vitro. Proceedings of IEEE Ultrasonics Symposium 2:981-984, 1993. Pritzker KPH: Animal models for osteoarthritis: processes, problems and prospects. Annals of the Rheumatic Diseases 53(6):406-420, June 1994. Xu Y, Pritzker KPH, Cruz TF: Characterization of chondrocyte alkaline phosphatase as a potential mediator in the dissolution of calcium pyrophosphate dihydrate crystals. The Journal of Rheumatology 21(5):912-919, 1994. Berkovitch M, Laxer RM, Inman R, Goren G, Pritzker KPH, Fritzier MJ, Olivieri NF: Arthropathy in thalassaemia patients receiving deferiprone. Lancet 343: 1471-1472, 1994. Pritzker KPH: Calcium pyrophosphate dihydrate crystal deposition and other crystal deposition diseases. Current Opinion in Rheumatology 6:442-447, 1994. Mass PG, Pritzker KPH, Mendes MG, Boskey AL, Weiser H: Vitamin B 6 deficiency experimentally- induced bone and joint disorder: microscopic radiographic and biochemical evidence. British Journal of Nutrition 71(6):919-932, 1994.

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Dr. K.P.H. Pritzker PUBLICATIONS 164. Shinozaki T, Pritzker KPH: Implications of alkaline phosphatase pyrophosphatase activity:

Intracellular functions of alkaline phosphatase. J Jpn Orthop Assoc 68:545-551, 1994. Pritzker KPH: Gout and The Gullible. Editorial. The Journal of Rheumatology 21:12, 1994. Grynpas MD, Gahunia HK, Yuan J, Pritzker KPH, Hartmann D, Tupy JH: Analysis of collagens solubilized from cartilage of normal and spontaneously osteoarthritic rhesus monkeys. Osteoarthritis and Cartilage 2:227-234, 1994. Grynpas MD, Holmyard DP, Pritzker KPH: Bone mineralization and histomorphometry in biopsies of osteoporotic patients treated with fluoride. Cells and Materials 4(3):287-297, 1994. Shinozaki T, Xu Y, Cruz TF, Pritzker KPH: Calcium pyrophosphate dihydrate (CPPD) crystal dissolution by alkaline phosphatase: Interaction of alkaline phosphatase on CPPD crystals. The Journal of Rheumatology 22(1):117-123, 1995. Juzen Medical Society Award, Kanazawa University. Khan AA, Ahmed MM, Pritzker KPH: Osteoporosis associated with pregnancy. Case report and review. Endocrine Practice 1(4):236-238, 1995. Gahunia HK, Lemaire C, Babyn PS, Cross AR, Kessler MJ, Pritzker KPH: Osteoarthritis in rhesus macaque knee joint: Quantitative magnetic resonance imaging tissue characterization of articular cartilage. J Rheumatol 22:1747-1756, 1995. Shinozaki T, Pritzker KPH: Polyamines enhance calcium pyrophosphate dihydrate crystal dissolution. J Rheumatol 22:1907-1912, 1995. Grynpas MD, Kasra M, Renlund R, Pritzker KPH: The effect of pamidronate in a new model of immobilization in the dog. Bone 17(4):2255-2325, 1995. Gahunia HK, Babyn P, Lemaire C, Kessler MJ, Pritzker KPH: Osteoarthritis staging: Comparison between magnetic resonance imaging, gross pathology and histopathology in the rhesus macaque. Osteoarthritis and Cartilage 3:169-180, 1995. Kim HKW, Babyn PS, Harasiewicz KA, Gahunia HJK, Pritzker KPH, Foster FS: Imaging of immature articular cartilage using ultrasound backscatter microscopy at 50 MHz. J Orthopedic Research 13(6):963-970, 1995. Babyn P, Kim HKW, Lemaire C, Gahunia HK, Cross A, DeNanassy J, Pritzker KPH: High- resolution magnetic resonance imaging of normal porcine cartilagenous epiphyseal maturation. J Magn Reson Imaging 1:172-179, 1996.

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Dr. K.P.H. Pritzker PUBLICATIONS 176. Shinozaki T, Pritzker KPH: Regulation of alkaline phosphatase: Implications for calcium

pyrophosphate dihydrate crystal dissolution and other alkaline phosphatase functions. J Rheumatol 23:677-683, 1996. Lim KKT, Kessler MJ, Pritzker KPH, Turnquist JE, Dieppe PA: Osteoarthritis of the hand in nonhuman primates: A clinical, radiographic, and skeletal survey of Cayo Santiago rhesus macaques. J Med Primatol 25:301-308, 1996. Duncan M, Crawshaw GJ, Mehren KG, Pritzker KPH, Mendes M, Smith DA: Multicentric hyperostosis consistent with fluorosis in captive fruit bats (Pteropus Giganteus, P.Poliocephalus, and cRousettus Aegyptiacus). Journal of Zoo and Wildlife Medicine 27(3):325-338, 1996. Ghazavi MT, Pritzker KPH, Davis AM, Gross AE: Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee. Journal of Bone and Joint Surgery 79B(6):1008-1013, 1997. Andrulis IL, Bull SB, Blackstein ME, Sutherland DA, Mak C, Sidlofsky S, Pritzker KPH, Hartwick RW, Hanna W, Lickley L, Wilkinson R, Qizilbash A, Ambus U, Lipa M, Weizel HE, Katz A, Baida M, Mariz S, Stoik G, Da Camara P, Strongitharm D, Geddie W, McCready D. for the Toronto Breast Cancer Study Group. neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. J. Clin. Oncol. 16(4);1340-1349, 1998. Shinozaki T, Watanabe H, Takagishi K, Pritzker KPH: Allotype immunoglobulin enhances alkaline phosphatase activity: Implications for the inflammatory response. J Lab and Clin Med 132;320-328, 1998. Babyn PS, Kim HKW, Gahunia HK, Lemaire C, Salter RB, Fornasier V, Pritzker KPH: MRI of the cartilaginous epiphysis of the femoral head in the piglet hip after ischaemic damage. J Magn Reson Imaging 8(3);717-723, 1998. Peters WJ, Pritzker KP, Smith DC, Fornasier V, Holmyard D, Lugowski S, Kamel M, Visram F: Capsular calcification associated with silicone breast implants: Incidence, determinants, and characterization. Annals of Plastic Surgery 41(4):348-360, December 1998. Bapat B, Noorani H, Cohen Z, Berk T, Mitri A, Gallie B, Pritzker KPH, Gallinger S, Detsky A: Cost comparision of predictive genetic testing versus clinical screening for familial adenomatous polyposis. Gut 44:698-703, 1999. Gur E, Chiodo AA, Neligan PC, Pang CY, Mendes M, Pritzker KPH, Neligan PC, Shpitzer T, Forrest CR: The vascularized pig fibula bone flap model: Effects of multiple segmental osteotomies on growth and viability. Plast Reconstr Surg 103(5):1436-1442, 1999.

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Dr. K.P.H. Pritzker PUBLICATIONS 186. Johnson K, Moffa A, Chen Y, Pritzker KPH, Goding J, Terkeltaub R: Matrix vesicle plasma cell

membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells. Journal of Bone and Mineral Research 14(6):883-892, 1999. Peters W, Smith D, Lugowski S, Pritzker KPH: Simaplast inflatable breast implants: Evaluation after 23 years in situ. Plast Reconstr Surg 104(5):1539-1544, October 1999. Zhao YF, Mendes M, Symington JM, Listrom RD, Pritzker KPH: Experimental Study of Bone Growth Around a Dental Implant After Surgibone Grafting. Int J Oral Maxillofac Implants 14(6): 889-897,1999. Liu R, O!Connell M, Johnson K, Pritzker K, Mackman N, Terkeltaub R: Extracellular signal- regulated kinase 1/extracellular signal-regulated kinase protein kinase signaling and activation of activator protein 1 and nuclear factors play central froles in interleukin-8 expression stimulated by monosodium and calcium pyrophosphate crystals in monocytic cells. Arth & Rheum 43(5): 1145-1155, May 2000. Peters W, Smith D, Lugowski S, Pritzker KPH, Holmyard D: Calcification properties of saline- filled breast implants. Plastic & Reconstr Surg 107(2): 356-363, Feb. 2001

Joiner GA, Bogoch ER, Pritzker, KP, Buschmann MD, Chevrier A, Foster FS: High frequency acoustic parameters of human and bovine articular cartilage following experimentally-induced matrix degradation. Ultrason Imaging 23(2): 106-116, April 2001. Johnson K, Hashimoto S, Lotz M, Pritzker KPH, Goding J, Terkeltaub R: Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase (PDNP) family member plasma cell membrane glycoprotein-1 (PC-1) is a marker and pathogenic factor for knee meniscal cartilage matrix calcification. Arth & Rheum 44(5): 1071-1081, May 2001. Johnson K, Hashimoto S, Lotz M, Pritzker KPH, Terkeltaub R: Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. Amer J Path 159(1): 149-163, July 2001. Modi G, Vieth R, Hon J, Pritzker KPH: Good laboratory practice: Internal benchmarking for proficiency testing performances. Can J Med Lab Sc 63: 98-101, 2001 O’Donovan D, Lescala G, Yeung I, Zeman V, Mendes M, Leong I, Pritzker KPH, Pang CY, Neligan P, Forrest CR: Development of cytoprotective strategies for the prevention of radiation induced craniofacial bone growth inhibition in an infant rabbit model. Craniofacial Surgery 9: 101- 103, 2001.

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Dr. K.P.H. Pritzker PUBLICATIONS 196. Gahunia HK, Lough A, Vieth R, Pritzker KPH: A cartilage derived novel compound DDP (2,6-dimethyldifuro-8-pyrone): Isolation, purification and identification. J Rheum 29(1): 147-153, Jan. 2002.

Gahunia HK, Vieth R, Pritzker KPH: Novel fluorescent compound (DDP) in calf, rabbit and human articular cartilage and synovial fluid. J Rheum 29(1): 154-160, Jan. 2002 McGoveran BM, Pritzker KPH, Shasha N, Price J, Gross AE: Long-term chondrocyte viability in a fresh osteochondral allograft. J Knee Surg 15(2): 97-100, Spring 2002 Li Chris, Cantor WJ, Nili N, Robinson R, Fenkell L, Tran YL, Whittingham HA, Tsui W, Cheema AN, Sparkes JD, Pritzker KPH, Levy DE, Strauss BH: Arterial repair after stenting and the effects of GM6001, a matrix metalloproteinase inhibitor. J Amer College Cardio 39(11): 1825-1858, June 5, 2002 Pritzker KPH: Cancer biomarkers: easier said than done. Clin Chem 48(8): 1147-1150, Aug. 2002 Mainil-Varlet P, Aigner T, Brittberg M, Bullough P, Hollander A, Hunziker E, Kandel R, Nehrer S, Pritzker K, Roberts S, Stauffer E: Histological assessment of cartilage repair: A report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS). J Bone Joint Surg 85-A(Suppl 2): 45-57, 2003 Goss PE, Qi S, Josse RG, Pritzker KPH, Mendes M, Hu H, Waldman SD, Grynpas MD: The steroidal aromatase inhibitor exemestane prevents bone loss in ovariectomized rats. Bone 34(3): 384-392, March 2004 Pritzker KPH, Azad A: Genomic biomarkers for cancer assessment: Implementation challenges for laboratory practice. Clin Biochem 37: 642-646, July 2004. Goss PE, Qi S, Cheung AM, Hu H, Mendes M, Pritzker KPH: Effects of the steroidal aromatase inhibitor exemestane and the non-steroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. Clin Canc Res 10: 5717-5723, September 2004. Pritzker, KPH: Nonhuman primate seronegative arthritis: probability values for valuable science in a case report. (Editorial) Jour Rheum 31(11): 2102-2103, November 2004. Goss PE, Qi S, Cheung AM, Hu H, Mendes M, Pritzker KPH: The selective estrogen receptor modulator SCH 57068 prevents bone loss, reduces serum cholesterol and blocks estrogen-induced uterine hypertrophy in overiectomized rats. J Steroid Biochem Mol Biol 92: 79-87, September 2004.

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Dr. K.P.H. Pritzker PUBLICATIONS 207. Verma S, Hauck T, El-Khouly ME, Padmawar PA, Canteenwala T, Pritzker K, Ito O, Chiang LY: Self-assembled photoresponsive amphiphilic diphenylaminofluorene-C60 conjugate vesicles in

aqueous solution. ACS Journal "Langmuir" 21(8): 3267-3272, April 12, 2005. Liu-Bryan R, Pritzker KPH, Firestein GS, Terkeltaub R: TRL2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation.

J Immuno 174(8): 5016-5023, Apr 15, 2005. Yu C, Canteenwala T, El-Khouly ME, Araki Y, Chiang LY, Wilson BC, Ito O, Pritzker KPH: Efficiency of singlet oxygen production from nanospheres of molecular micelle-like photodynamic sensitizers hexa(sulfo-n-butyl)[60]fullerenes (FC 4 S). J of Materials Chemistry 15: 1857-1864, May 14, 2005. So G, Karotki A, Verma S, Hauck TS, Wilson B, Pritzker KPH, Chiang LY: Singlet oxygen production by amphiphilic C 60 derivatives and its correlation to cell cytotoxicity in vitro. International Society for Optical Engineering, Photonics North, Sept 12, 2005. Hauck TS, Padmawar PA, Canteenwala T, Pritzker KPH, Chiang LY: Characterization of chemically grafted carbon nanotubes by EELS spectroscopy. International Society for Optical Engineering, Photonics North, Sept 12, 2005. Yu C, Canteenwala T, Chiang LY, Wilson B, Pritzker KPH: Photodynamic effect of hydrophilic C 60- derived nanostructures for catalytic antitumoral antibacterial application. Synthetic Metals 153: 37-40, Sept 21, 2005. Verma S, Padmawar PA, Hauck T, Canteenwala T, Chiang LY, Pritzker KPH: Synthesis of water- soluble highly two-photon responsive [60]fullerene-diphenylaminofluorene chromophore dyads. J Macromol Sci Pure Appl Chem 42: 1497-1505, Nov 2005. Pritzker KPH, Azad A: Bringing biomarkers to clinical practice. Clinical Lab International 25: 24- 26, Nov 2005. Pritzker KPH, Gay S, Jimenez SA, Ostergaard K, Pelletier J-P, Revell PA, Salter D: Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis and Cartilage 14: 13- 29, Jan 2006. (noted as one of the 10 most downloaded articles from the journal ScienceDirect between Jan. and Mar. 2006) So G, Karotki A, Verma S, Pritzker KPH, Wilson B, Chiang LY: Comparison of singlet oxygen generation efficiency between water-soluble C 60 -diphenylaminofluorene conjugates and molecular micelle-like FC 4 S. J of Macromol Sci 43: 1-9, 2006.

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Dr. K.P.H. Pritzker PUBLICATIONS 217. Doria AS, Noseworthy MD, Oakden W, Moineddin R, Rayner T, Tassos V, Engelberts D, Pritzker KPH, Rogers M, Jong R, Babyn PS: Dynamic contrast-enhanced MRI quantification of synovium

microcirculation in experimental arthritis. Am Jour Roentgenology 186: 1165-1171, April 2006. Doria AS, Kharshafian R, Moineddin R, Mohanta A, Zhong A, Mendes M, Pritzker KPH, Jong R, Burns P: Contrast-enhanced triggered harmonic sonography for assessment of periarticular hemodynamic changes in experimental arthritis. Pediatric Radiology 36(12): 1242-1251, December 2006. Maury AC, Safir O, Las Heras F, Pritzker KPH, Gross AE: Twenty-five year chondrocyte viability in fresh osteochondral allograft: a case report. J of Bone & Joint Surg Am 89(1): 159- 165, January 2007. Las Heras F, Pritzker KPH, Colgan TJ: Chordoma arising in a mature cystic teratoma of the ovary: a case report. Path Res and Prac 203(6): 467-471, June 2007. So PPL, Tsui FWL, Vieth R, Pritzker KPH: Inhibition of alkaline phosphatase by cysteine: implication for calcium pyrophosphate dihydrate crystal deposition disease. J Rheum 34(6): 1313- 1322, June 2007. Wang J, Wang C, Tsui HW, Las Heras F, Cheng EY, Iscore N, Chiu B, Inman RD, Pritzker KPH, Tsui FWL: Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation. Exp Cell Res 313:4120-4129, 2007 Hough TA, Polewski M, Johnson K, Cheeseman M, Nolan PM, Vizor L, Rastan S, Boyde A, Pritzker KPH, Hunter AJ, Fisher EMC, Terkeltaub R, Brown SDM: A novel mouse model of autosomal semi-dominant adult Hypophosphatasia has a splice sute mutation in the tissue non- specific alkaline phosphatase gene Akp2. J Bone & Mineral Res, 22(9):1397-1407, September 2007.

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Dr. K.P.H. Pritzker PUBLICATIONS IN PRESS: Pritzker KPH: Crystal deposition in joints: prevalence and relevance for arthritis. J Rheum 2008

PUBLICATIONS SUBMITTED: Gross AE, Kim W, Las Heras F, Backstein D, Safir O, Pritzker KPH: Fresh osteochondral allografts for posttraumatic knee defects: long-term follow-up. Clinical Orth & Related Research Las Heras F, Pritzker KPH, Tsui HW, Chiu B, Tsui F, Inman RI: Cellular events associated with joint ankylosis: morphometric and immunohistochemical studies in the ank/ank mouse. Am College of Rheum Lau KHV, Anandakathir R, Pritzker KPH, Chiang LY: Solvent and concentration-dependent aggregation study of C 60 dyads and multiads onnonlinear photonic properties. JMS Tsui FWL, Wang J, Wang C, Tsui HW, Cheng EY, Chiu B, Iscove N, Pritzker KPH, Inman RD: Mean corpuscular volume in experimental and clinical spondylitis. J Clinical Investigation

PUBLICATIONS IN PREPARATION: Baker RE, Dickson BC, Veith R, Pritzker KPH: The fluorescent molecule, dimethyldifuropyrone, is formed during acid-catalyzed hydrolysis of articular cartilage glycosaminoglycans. Gahunia HK, Babyn P, Kessler MJ, Pritzker KPH: Spontaneous osteonecrosis of the knee (sonk) in rhesus monkeys. Gahunia HK, Lemaire C, Babyn P, Kim HDW, Pritzker KPH: High resolution magnetic resonance imaging of bovine articular cartilage. J Skeletal Radiology. Molto JE, Sheldrick P, Babyn P, Rothschild B, Pritzker KPH: Cancer in a Romano-Christian period child skeleton from Dakhleh, Egypt. Wang J, Tsui HW, Beier F, Pritzker KPH, Inman RD, Tsui FWL: ANKH mutations in chondrocalcinosis affect chondrocyte differentiation and different aspects of PPi/Pi metalbolism. J Clin Invest

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Dr. K.P.H. Pritzker BOOK CHAPTERS 1. Matthews JL, Arnott HJ, Brown WE, Dosch W, Hascall VS, Hautmann R, Krampitz GP, Munzenberg KJ, Pritzker KPH, Prockop DJ, Schenk RK, Watanabe N, Young RA: Structure, properties and

function of mineralized tissue components, Group report. In Biological Mineralization and Demineralization, (ed. G.H. Nancollas), Life Sciences Report #23, Dahlem Konferenzen 1982, pp. 327-348, Berlin, Heidelberg, New York: Springer-Verlag. Gross AE, McKee NH, Langer F, Pritzker KPH: Surgical techniques and clinical experience with articular allografts at the knee. In: Osteochondral Allografts, (ed. G.E. Friedlaender), Little, Brown and Company, 1983, p. 289-298. Pollard A, Pritzker KPH, Grynpas MD: Disorders of calcium, magnesium, and bone metabolism, Chapter 17. In: Applied Biochemistry of Clinical Disorders, 2nd edition. (Gornall AG et al, ed). Lippincott, Chapter 17, pp 403-419, 1986. Pritzker KPH: Articular-skeletal system, muscle, fat and other connective tissues. In: Functional endocrine pathology. (Asa S, Kovacs K et al, eds). Blackwell Scientific Publications, Cambridge, MA, USA 1991: Chapter 26, pp 699-723. Pritzker KPH: Connective tissue. In: Encyclopedia of Human Biology, Volume 2. (Dulbecco R et al, eds). Academic Press Inc., San Diego, CA, USA, 1991: pp 639-648. Pritzker KPH: Cartilage histopathology in human and Rhesus Macaques osteoarthritis. In: Articular Cartilage and Osteoarthritis. (Kuettner KE, Schleyerbach R, Hascall VC, Peyron JG eds). Raven Press, Chapter 33, pp 473-485, 1992. Gahunia HK, Lemaire C, Cross AR, Babyn P, Kessler MJ, Pritzker KPH: Osteoarthritis in Rhesus Macaques: assessment of cartilage matrix quality by quantitative magnetic resonance imaging. In: Joint Destruction in Arthritis and Osteoarthritis. (W.B. van den Berg et al eds). Birkhauser Verlag Basel, 1993, AAS39, pp 255-259. Pritzker KPH: Biomineralization and Calcification. In: Encyclopedia of Human Biology. (Renato Dulbecco, ed), Academic Press, San Diego, CA, 1997, 2nd edition, Vol. 1, pp. 797-807. Pritzker KPH: Connective Tissue. In: Encyclopedia of Human Biology. (Renato Dulbecco, ed),Academic Press, 1997, 2nd edition, San Diego, CA, Vol. 3, pp. 11-20. Pritzker KPH: Pathology of Osteoarthritis. In: Osteoarthritis. (Eds. Brandt KD, Doherty M, Lohmander S), Oxford University Press, 1998, pp 50-61. Pritzker KPH: Calcium pyrophosphate crystal formation and dissolution. In: Calcium Phosphates in Biological and Industrial Systems. (Amjad Z, ed.) Kluwer Academic Publishers, Boston, 1998: Chapter 12, pp. 277-301.

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Dr. K.P.H. Pritzker BOOK CHAPTERS 12. Pritzker KPH: The articular-skeletal system: Muscle, fat and other connective tissues. In: Functional

Endrocine Pathology, 2nd Edition, (Kovacs K, Asa S, eds.), Blackwell Science Inc., Cambride, MA, Chapter 26, 1998:699-723. Pritzker KPH, Kessler MJ: Diseases of the musculoskeletal system. In: Nonhuman Primates in Biomedical Research: Diseases, (Bennett BT, Abee C, Henrickson R, eds.), Academic Press Inc., San Diego, Volume II, Chapter 11, 1998:415-459. Fornasier V, Pritzker KPH, Bridge JA: Desmoplastic fibroma of bone. In: Pathology & Genetics: Tumours of Soft Tissue and Bone, (Fletcher CDM, Unni KK, Mertens F, eds.), International Agency for Research on Cancer Press, Lyon, France, Chapter 12, 2002: 288. Pritzker KPH: Pathology of Osteoarthritis. In: Osteoarthritis, 2 nd Edition. (Brandt KD, Doherty M, Lohmander S, eds.), Oxford University Press, Chapter 5, 2003:49-58.

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Dr. K.P.H. Pritzker ABSTRACTS 1. Koven IH, Pritzker KPH, Liswood A: The interstitial tissue barrier: a component of poor capillary flow. Annals at the Royal College of Physicians and Surgeons 8:82, 1975.

Houpt JB, Langer F, Gross AE, Pritzker KPH: Allotransplantation of joint surfaces in the treatment of osteonecrosis of the medial femoral condyle. Arthritis and Rheumatism 18:405, 1975. Czitrom A, Langer F, Pritzker KPH: Virus-induced osteosarcoma in rats: an experimental model for the study of human osteosarcomas. Journal of Bone and Joint Surgery 57A:583, 1975. Pritzker KPH, Houpt JB, Gross AE, Langer F: Pathology of spontaneous osteonecrosis of the knee (S.O.N.K.). Journal of Rheumatology, 3, p. 106, 1976. Annals of the Royal College of Physicians and Surgeons of Canada 9:44, 1976. Gordon AS, Starkman SP, Pritzker KPH, Langer F: Scapulo-peroneal "dystrophy". Canadian Journal of Neurological Sciences 3:150, 1976. Pritzker KPH: Cellular events in intervertebral disc degeneration. Arthritis and Rheumatism 19:817, 1976. Pritzker KPH, Gross AE, Langer F, Luk SC, Houpt JB: Articular cartilage allotransplantation: histological studies. Proceedings of the XI International Congress, International Academy of Pathology, Washington, D.C., p. 203, 1976. Pritzker KPH, Zahn CE, Nyburg SC, Luk SC, Houpt JB: Crystal ultrastructure and the pathogenesis of gout and pseudogout. Annals of the Royal College of Physicians and Surgeons of Canada 10:97, 1977. Fam A, Stein J, Pritzker KPH, Little H: Hydroxyapatite arthropathy: a clinical study of 11 "probable" cases. Annals of the Royal College of Physicians and Surgeons of Canada 10:99, 1977. Pritzker KPH, Nyburg SC: Intervertebral disc calcifications in the elderly: calcium pyrophosphate dihydrate arthropathy. Laboratory Investigation 36:358, 1977. Czitrom A, Langer F, Gross AE, Pritzker KPH, West M, Urovitz EP: Immunotherapy of a virus induced experimental osteosarcoma. Orthopedic Transactions 1:30, 1977. Adams ME, Pritzker KPH, Nyburg SC, Cheng P-T: The search for apatite arthropathy. Annals of the Royal College of Physicians and Surgeons 10:92, 1978. Pritzker KPH: The pathology of gout and pseudogout. VII Congreso Panamericano de Reumatologia Resumenes, 1978.

2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.

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Dr. K.P.H. Pritzker ABSTRACTS 14. Gordon AS, Pritzker KPH, Berris B, Britt BA: Malignant hyperthermia is more common than we think.

Proceedings of the IVth International Congress on Neuromuscular Diseases Montreal, September 1978. Pritzker KPH, Adams ME, Cheng P-T, Nyburg SC: Calcium pyrophosphate dihydrate crystal formation in gels and solutions. Annals of the Royal College of Physicians and Surgeons of Canada 12:93, 1979. Fam AG, Little AH, Gertzbein S, Pritzker KPH: Cholesterol associated synovitis: a clinico-pathological study of eight patients. Annals of the Royal College of Physicians and Surgeons of Canada 12:94, 1979. Pritzker KPH, Cheng P-T, Nyburg SC, Adams ME: Micro x-ray diffraction: definitive crystal identification in tissue sections. Laboratory Investigation 14:42, 1979. Cheng P-T, Nyburg SC, Omar SA, Pritzker KPH: Crystallography in clinical and experimental studies of calcium pyrophosphate crystal formation. Proceedings of the American Crystallographic Association, March 1979. Pritzker KPH, Renlund RC, Cheng P-T: Calcium pyrophosphate crystal arthropathy in femoral heads. Laboratory Investigation 42:144, 1980. Pritzker KPH, Cheng P-T, Omar SA, Nyburg SC: Articular cartilage as a model gel for the study of calcium pyrophosphate crystal formation. Annals of the Royal College of Physicians and Surgeons of Canada 13:169, 1980. Houpt JB, Alpert A, Lotem M, Greyson ND, Pritzker KPH, Langer F, Gross AE: Spontaneous osteonecrosis of the medial tibial plateau. Clinical Research 29:158A, 1981. Pritzker KPH, Gross AE, Houpt JB: Femoral condyle osteonecrosis. Laboratory Investigation 44:53A, 1981. Houpt JB, Alpert B, Greyson ND, Lotem M, Pritzker KPH, Gross AE: Natural history of spontaneous osteonecrosis of the knee. Revue du Rhumatisme, numero special 912, June 1981. Pritzker KPH, Cheng P-T: Clinical pathologic aspects of crystal deposits. Journal of Rheumatology 8:1004, 1981.

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Dr. K.P.H. Pritzker ABSTRACTS 25. Sweet J.M., Pritzker KPH, Cheng P-T: Calcium oxalate crystal deposits in granulomas. Journal of

Rheumatology 8:1006, 1981. Cheng P-T, Adams ME, Nyburg SC, Pritzker KPH: Effect of various ions on calcium pyrophosphate crystal formation. Journal of Rheumatology 8:1015, 1981. Cheng P-T, Pritzker KPH, Tagliabracci L, Millard J, Reid A: Crystal and stone analysis. Clinical Biochemistry 15:96, 1982. Kliman ME, Gross AE, Pritzker KPH, Greyson ND: Osteochondritis of the hallux sesamoid bones. Orthopaedic Transactions 6:184, 1982. Kandel RA, Gamel A, Langer F, Gross AE: The histopathology of osteoarticular shell allografts. Laboratory Investigation 48(1):42A, 1983. Pritzker KPH, Cheng P-T and Reid AD: Calcium pyrophosphate crystal arthropathy: ultrastructural studies. Laboratory Investigation 50:30, 1984. Cheng P-T and Pritzker KPH: Alternating crystallisation - a proposed mechanism for lamellar structure formation in renal stones. Urological Research 12:92, 1984. Simmons ED, Grynpas MD, Pritzker KPH and Harrison JE: Fluoride induced changes in bone mineral. Orthopaedic Transactions, 1984. Cheng P-T, Reid AD and Pritzker KPH: Ultrastructural studies of the organic matrix in kidney stones from children. Proceedings of the 3rd Asia-Pacific Conference on Electron Microscopy, Singapore, August 29 - September 2, 1984, pp. 310 - 313. Gross AE, Ganel I, Langer F, Pritzker KPH, Krensky R, Kandel RA, McDermott AGP: Analysis of the histopathology failed fresh osteochondral allografts. Orthopedic Transactions 8:399, 1984. Hunter GK, Grynpas MD, Pritzker KPH: Role of proteoglycan in pathogenesis of pyrophosphate arthropathy. Clinical Science 33:777A, 1985. Hunter GK, Allen BL, Cheng P-T, Pritzker KPH: Effect of cartilage proteoglycan on hydroxyapatite formation in collagen gels. Chemistry and Biology of Mineralized Tissues. Ed. W. Butler, Ebsco Media Inc., p. 424, 1985. Renlund RC, Pritzker KPH, Kessler MJ: Rhesus primates (Macaques Mulatta) as a model for calcium pyrophosphate dihydrate crystal deposition disease. Laboratory Investigation 52:55A, 1985. Pritzker KPH, Kessler MJ, Renlund RC, Turnquist J, Tepperman PF: Degenerative arthritis in aging Rhesus Macaques. American J of Primatology 8:358, 1985.

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Dr. K.P.H. Pritzker ABSTRACTS 39. Grynpas MD, Pritzker KPH, Kessler MJ: Cortical bone aging in free-ranging Rhesus monkeys.

American J of Primatology 8:341, 1985. Deitel M, Thompson DA, Saldanha CF, Patterson MC, Pritzker KPH: Pink urine in morbidly obese patients following stapling gastroplasty. J. American College of Nutrition 4:359, 1985. Alpert B, Grynpas MD and Pritzker KPH: Qualitative changes in subchondral bone mineral in osteoarthritis. Transactions of the 31st meeting of the Orthopaedic Research Society, Las Vegas, January 1985, p. 77. Vieth R, Kessler MJ, Pritzker KPH: Effect of age on vitamin D metabolites in serum in Cayo Santiago Rhesus monkeys macaques. Am J Primatol 10:437, 1986. Pritzker KPH, Chateauvert J, Grynpas MD: Calcium, phosphorus, magnesium and sulphur content of osteoarthritic cartilage. Clinical and Investigative Medicine 9:A159, 1986. Katz I, Pritzker KPH and Grynpas MD: Qualitative bone mineral changes in osteoporosis. Orthopaedic Research Society Transactions, 33rd Annual Meeting 12:263, 1987. Huckell CB, Grynpas MD, Pritzker KPH: Ageing and osteoporosis in free ranging Rhesus monkeys. 21st Annual Meeting of the Canadian Orthopaedic Research Society, London, Ontario, June 1987, no. 29. Fam AG, Schumacher HR, Clayburne G, Sieck M, Mandel N and Pritzker KPH: A comparison of 5 preparations of synthetic monosodium urate crystals (MSUC). Arthritis & Rheumatism 30 (4), 1987. Cheng P-T, Bader SM, Pritzker KPH, Grynpas MD: Fluoride affects trabecular bone more than cortical bone. Transactions of the 34th Annual Meeting, Orthopaedic Research Society 13:371, 1988. Grynpas MD, Pritzker KPH and Kessler MJ: Age related bone changes in Rhesus monkeys. Orthopaedic Transactions Research Society 13:533, 1988. Keating SJ and Pritzker KPH: The autopsy diagnosis of short-rib polydactyly syndrome type 1. Canadian Congress of Laboratory Medicine, Winnipeg, Manitoba, June 27, 1988, p.58. Lieberman I, Bogoch E, Pritzker KPH, Grynpas MD: Subchondral bone changes in the femoral heads of patients with rheumatoid arthritis. 22nd Canadian Orthopaedic Res. Society, Ottawa, Ontario, June 1988. Kandel RA, Pritzker KPH, Cruz TF: Effect of fetal bovine serum and interleukin 1 on collagenase and proteoglycan production by bovine chondrocytes. Arthritis & Rheumatism, 1988 Regional Meetings of the American College of Rheumatology, 32:(1 Supplement):R17 #B29N, January 1989.

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Dr. K.P.H. Pritzker ABSTRACTS 52. Chateauvert JD, Grynpas MD, Kessler M, Pritzker KPH: Spontaneous osteoarthritis in a Rhesus

monkey population. Arthritis & Rheumatism, 1988 Regional Meetings of the American College of Rheumatology, 32:(1 Supplement):R7 #14N, January 1989. Keating SJ, Pritzker KPH: Aneurysmal bone cysts containing chondroid bone. Investigation, Annual Meeting Abstracts, 60(1):46A, #271, January, 1989. Laboratory 53.

54. Renlund RC, Pritzker KPH, Kessler MJ: Calcium pyrophosphate dihydrate crystal deposition disease: a common disease of aging human and non-human primates. Laboratory Investigation, Annual Meeting Abstracts, 60(1):78A, #461, January, 1989. Tornos C, Silva EG, El-Naggar A, Pritzker KPH: Calcium oxalate crystals in breast biopsies: the missing microcalcifications. Laboratory Investigation, Annual Meeting Abstracts, 60(1):97A, #596, January, 1989. Grynpas MD, Alpert B, Lieberman IH, Pritzker KPH: Changes in bone mineralization in osteoarthritis. Calcified Tissue International, The XXI European Symposium on Calcified Tissue, 44(Supp):S82, 1989. Pritzker KPH, Holmyard D, Slomovic A & Heathcote JG: The calcification of band keratopathy. Calcified Tissue International, The XXI European Symposium on Calcified Tissue 44(Supp):S78, 1989. Keating S, Wunder J, Andrulis I, Czitrom A, Bell R, Pritzker K: MDR1 gene expression in soft tissue tumours as measured by the polymerase chain reaction. Modern Pathology 3(1):#293 pp 51A, 1990. Bayley TA, M ller C, Harrison J, Basualdo J, Sturtridge W, Josse R, Murray TM, Pritzker KPH: The long term treatment of steroid osteoporosis with fluoride. J Bone and Mineral Res 5(suppl. 1):S227, March, 1990. Pritzker KPH, Grynpas MD, Harrison JE: Observed versus predicted concentrations of bone fluoride in osteoporotic patients: implications for assessment of fluoride effect. J Bone and Mineral Res 5(suppl. 1):S235, March, 1990. Fam AGH, Pritzker KPH: Acute calcific periarthritis in scleroderma. American College of Rheumatology Northeast Meeting. Arthritis Rheumatol 34(Suppl):R41, 1991. Grynpas MD, Holmyard D, Pritzker KPH: Bone mineral quality in biopsies of osteoporotic patients treated with fluoride. Calcified Tissue International (Abstracts: 22nd European symposium on Calcified Tissues, Vienna, Austria, March, 1991) 48(Suppl):168, 1991.

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Dr. K.P.H. Pritzker ABSTRACTS 63. Pritzker KPH, Huang X, Keating SJ: Peripheral mixed osteoblastoma. United States/Canadian

Academy of Pathology, Chicago, March 18, 1991, Laboratory Investigation 64(1):8A #35, January, 1991. Xu Y, Cruz T, Pritzker KPH: The potential role of alkaline phosphatase in dissolution of calcium pyrophosphate dihydrate crystals in articular cartilage. J Cell Biol 115(3)Part 2:471a, November 1991. Pritzker KPH, Xu Y, Cruz TF: Alkaline phosphatase: a novel therapeutic strategy for calcium pyrophosphate dihydrate crystal dissolution in cartilage. Connective Tissue Research J, 4th International Conference of chemistry and biology of mineralized tissues. 27(2-3):185, 1992. Kessler MJ, Pritzker KPH: Osteoarthritis and bone pathology of nonhuman and human primates. American J of Primatol 27 (1), #38, 1992. Pilavdzic D, Olivieri NF, Pritzker KPH: Synovial pathology in -thalassemia. Modern Pathology, 6(1): #36, 1993 and Laboratory Invest 68(1):10A #36, 1993. HONOURABLE MENTION. Society of Ultrastructural Pathology. Lim KKT, Kessler M, Pritzker K, Dieppe PA: Osteoarthritis of the hand in a non human primate. Osteoarthritis and Cartilage 2(Suppl 1), #28, 1994. Babyn P, Gahunia HK, Harasiewicz K, Foster FS, Kim HKW, Pritzker KPH: Ultrasound backscatter microscopy (UBM) of normal and osteoarthritic articular cartilage at 50 MHz. Osteoarthritis and Cartilage 2(Suppl 1), #29, 1994. Pritzker KPH, Gahunia H, Babyn P, Lemaire C, Kessler MJ: Assessment of osteoarthritis staging: Severity correlation between radiographic imaging and pathology. Osteoarthritis and Cartilage 2(Suppl 1), #31, 1994. Gahunia HK, Lemaire C, Babyn P, Cross A, Kessler MJ, Pritzker KPH: Qualitative and quantitative analysis of osteoarthritic cartilage lesions using magnetic resonance imaging. Osteoarthritis and Cartilage 2(Suppl 1), #41, 1994. Wang R-n, Cai J-c, Hiruki T, Pritzker KPH, Redston M, Bapat BV: Microsatellite instability in gastric carcinomas in China. Laboratory Investigation 74(1):382, 1996 and Modern Pathology 9(1):382, 1996. Pritzker KPH, Lee, J-Y, Mendes M: Tetracycline surfaces can exceed osteoid surfaces: Implications for bone mineralization. Connective Tissue Research 35(1-4):296[350], 1996. Shinozaki T, Pritzker KPH: Alkaline phosphatase, pyrophosphatase activity, and calcium pyrophosphate dihydrate crystal dissolution. Connective Tissue Research 35(1-4):300[354], 1996.

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Dr. K.P.H. Pritzker ABSTRACTS 75. Holmyard DP, Shinozaki T, Pritzker KPH: FE-SEM examination of calcium pyrophosphate dihydrate crystal dissolution. Proceedings of Microscopical Society of Canada, 24:86-87, 1997.

Kessler MJ, Pritzker KPH: Naturally-occurring musculoskeletal diseases of aging nonhuman primates. American Journal of Primatology, 42(2):121, 1997. Gahunia HK, Karasiewicz K, Foster SF, Kessler MJ, Pritzker KPH: High frequency ultrasound imaging of normal and osteoarthritic rhesus macaque knee joints. Osteoarthritis and Cartilage, 5(Suppl. A):109, 1997. Gahunia HK, Harasiewicz K, Lemaire C, Foster SF, Pritzker KPH: Interleukin-1 induced damage to reconstituted articular cartilage: Assessment by magnetic resonance and ultrasound imaging. Osteoarthritis and Cartilage, 5 (Suppl. A):110, 1997. Gahunia HK, Lemaire C, Pritzker KPH: Reconstituted articular cartilage: Characterization by magnetic resonance imaging. Osteoarthritic and Cartilage, 5(Suppl. A): 111, 1997. Liu R, O!Connell M, Johnson K, Pritzker KPH, Mackman N, Terkeltaub R: Activation of both NF-kB and the map kinase ERK1/2 (p44/42) are essential for urate crystal (UC) and CPPD crystal-induced expression of the chemokine IL-8 in monocytes. 41(9 suppl.):#1953, pp S358, September 1998. Johnson K, Moffa A, Pritzker KPH, Chen Y, Goding J, Terkeltaub R: UP-regulation of PC-1 immediately prior to the onset of hydroxyapatite deposition is essenial for osteoblasts to effectively mineralize their matrix. 41(9 suppl.):#1227, pp S237, September 1998. Wolfgang GHI, Seely L, Pike M, Hsyu P, Novicki D, Horvath C, Myers SL, Pritzker K: Efficacy and safety of recombinant human insulin-like growth factor (rhIGF-1) in a canine model of osteoarthritis. Toxicological Sciences 48(1S):174, 1999. Sali A, Favaloro JM, Pritzker KPH, Terkeltaub R, Goding JW: Germline deletion of the nucleoside triphosphate pyrophosphohydrolase (NTPPPH) plasma cell membrane glycoprotein 1 (PC-1) produces abnormal calcification of periarticular tissues. International Ecto-ATPase Meeting, Brussels, Belgium, June 1999. Gahunia HK, Tupy J, Vieth R, Pritzker KPH: Effect of interleukin-1 on collagen, collagen crosslinks and proteoglycan content of reconstituted articular cartilage. Osteoarthritis and Cartilage, 7 (Suppl. A): 47, September 1999.

76. 77. 78. 79. 80. 81. 82. 83.

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Dr. K.P.H. Pritzker ABSTRACTS

85. Gahunia HK, Vieth R, Pritzker KPH: A novel articular cartilage biochemical marker: chemical characterization. Osteoarthritis and Cartilage, 7 (Suppl. A): 90, September 1999. Gahunia HK, Vieth R, Pritzker KPH: Presence of cartilage marker-1 in bovine and lapine. Osteoarthritis and Cartilage, 7 (Suppl. A): 91, September 1999. Johnson K, Hashimoto S, Pritzker KPH, Lotz M, Terkeltaub R: Central role of plasma cell membrane glycoprotein-1 (PC-1) in the pathogenesis of meniscal CPPD deposition disease (CPPD-DD) of the knee. ACR 63rd Annual Scientific Meeting, Hynes Convention Center, Boston, Massachusetts, November 13-17, 1999. Pritzker KPH, Ostergaard K, Salter D: Towards standardization of osteoarthritis histopathology: terminology, topology and technology. Osteoarthritis and Cartilage, 8(Suppl.B):S17, October 2000. Tupy JH, Pritzker KPH: A novel cartilage derived compound, 2,5-dimethyldifuro-8-pyrone (DDP), in human osteoarthritic synovial fluid. Osteoarthritis and Cartilage, 9(Suppl.B):p S36, October 2001. Tupy JH, Baker R, Pritzker KPHP: 2,6-dimethyldifuro-8-pyrone (DDP) is associated with cartilage chondroitin sulphate. Osteoarthritis and Cartilage, 9(Suppl.B):p S36, October 2001. Waddell J, Pritzker KPH, Boynton E: Inflammatory cytokine response to polyethylene particles in two patient populations. Orthopedic Research Society, Dallas, Texas, February 9, 2002. Moridani MY, Pritzker KPH, Hoffman BR, Bromberg IL: Vitamin B12 absorption test in healthy human subjects. (Poster) May 2002 Laboratory Medicine Congress, Calgary, Alberta; University of Toronto Department of Laboratory Medicine and Pathobiology Research Day Graduate Students’ Poster Session, April 12, 2002; Clinical Biochem, 35(2):p160, 2002. Pritzker KPH, Laverty SP, Mendes MG: Histopathologic grading of experimental osteoarthritis. Osteoarthritis & Cartilage 11(Suppl A): pS9, 2003. Pritzker KPH, So P: Osteoarthritis and calcium pyrophosphate dihydrate crystal arthropathy. 9 th World Congress of the Osteoarthritis Research Society International, December 2-5, 2004, Chicago, Illinois, USA; Osteoarthritis and Cartilage, 12(Suppl B): pS51, 2004. So P, Pritzker KPH: Amino acids as endogenous inhibitors of alkaline phosphatase: implication for calcium pyrophosphate dihydrate crystal deposition disease. 11th Annual Canadian Connective Tissue Conference, May 26-28, 2005, Ecole Polytechnique de Montr al, Qu bec. Las Heras F, Pritzker KPH, Colgan TJ: Chordoma arising in a mature cystic teratoma of the ovary. Canadian Association of Pathologists Meeting, July 15-19, 2006, St. John’s, Newfoundland, Canada. Path Res & Practice 202(11): p817, 2006. (poster presentation)

86. 87.

88. 89. 90. 91. 92.

93. 94. 95. 96.

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Dr. K.P.H. Pritzker ABSTRACTS 97. Las Heras F, Safir O, Gross A, Pritzker KPH: Cartilage transplantation pathology: features of graft

failure and survival. XXVI Congress of the International Academy of Pathology, September 16-21, 2006, Montreal, QC, Canada. Mod Path 19(S3): p5, Sept 2006. Las Heras F, Inman R, Tsui F, Pritzker KPH: Ank/Ank mouse, an osteoarthritis model. 2006 World Congress on Osteoarthritis, December 7-10, 2006, Prague, Czech Republic. Osteoarthritis and Cart 14(Suppl B 2006): pS147, December 2006. Gahunia HK, Doria AS, Babyn PS, Houpt JB, Pritzker KPH: Secondary osteonecroosis in the pediatric knee joints: radiologic characteristics. 2006 World Congress on Osteoarthritis, December 7-10, 2006, Prague, Czech Republic. Osteoarthritis and Cart 14(Suppl B 2006): pS44, December 2006.

98. 99. 100. Verma S, So G, Karotki A, Pritker KPH, Wilson B, Chiang L: Biophotonic application of amphiphilic fullerene-fluorene adducts. 211 th Meeting of the Electrochemical Society, Chicago, Illinois, USA, May 6- 10, 2007. (poster presentation) 101. Lau V, Anandakathir R, Pritzker K, Tan L-S, Urbas A, Chiang LY: Solvent and concentration-dependent

morphological study of starburst c 60 diphenylaminofluorene adducts. Sukant Tripathy Annual Memorial Symposium 2007, Lowell, Massachusetts, USA, November 30, 2007.

102. Las Heras F, Bubbar V, Amato D, Gross AE, Pritzker AE: Gaucher Disease: bone histomorphology after enzyme replacement therapy. United States and Canadian Academy of Pathology, March 1-7, 2008. Laboratory Investigation 88(Suppl 1):p13A, January 2008.

SUBMITTED ABSTRACTS none

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Dr. K.P.H. Pritzker PATENTS US PATENT No. 6,696,578 (Applied June 1998) Entitled "Difuropyrone Derivatives" 1998-1999 Cartilage Marker-1 (CM-1) Harpal Gahunia, Kenneth Pritzker, Reinhold Vieth 2,6 - Dimethyl-Difuro-8-Pyrone and related compounds U.S. PATENT APPLICATION No. 20040038946 and PCT Patent Published Patent Application No. WO0180898 (Applied April 27, 2001) Entitle "Fullerene-based Drugs Targeted to Bone" Lon Wilson, Uri Sagman, Kelly Gonzales, Kenneth Pritzker Fullerene-based Drugs Targeted to Bone

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Dr. K.P.H. Pritzker Grants and Contracts Information will be provided upon request.

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