chromeleon 7 operational simplicity for the...
TRANSCRIPT
![Page 1: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/1.jpg)
Chromeleon 7 Operational Simplicity for the Laboratory
![Page 2: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/2.jpg)
• Introducing Chromeleon 7 • User Interface • Peak Detection Tools • eWorkflows™ • Interactive Charting • Reporting • Support for Third Party Instrumentation • Summary
Topics
![Page 3: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/3.jpg)
Introducing Chromeleon® 7
• New-generation Chromatography Data System
• “Simply Intelligent”
• Intelligent Functionality - it does everything you need!
• Operational Simplicity™ - everything is fast and easy!
• Simplifies all chromatography processes
![Page 4: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/4.jpg)
Chromeleon® 7 - Operational Simplicity
• Operational Simplicity™ was the core design principle
• Major design rules:
• Minimize number of steps needed to perform any task
• Make all steps easy to understand and easy to use
• Minimize time needed to perform any task
• Major features for Operational Simplicity:
• Modern user interface
• Peak detection and integration tools
• eWorkflows
• Data visualization tools
• Enterprise functionality
![Page 5: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/5.jpg)
USER INTERFACE
![Page 6: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/6.jpg)
User Interface
The Chromeleon User Interface consists of two major parts: • Chromeleon Console • Chromatography Studio
![Page 7: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/7.jpg)
Chromeleon Console
• Designed to provide easy navigation through your data
• Provides quick access to:
• Instruments • Data • eWorkflows
![Page 8: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/8.jpg)
Console – Quick Access to Information
8
Navigation Pane
Category Bars
![Page 9: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/9.jpg)
Thumbnails – Quick Access to Data
• Quick check to see if chromatogram ran properly
• Check for presence / absence of peaks
• Check quality of separations
![Page 10: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/10.jpg)
Instruments - ePanels
Provides access to all instruments on the network
Direct Control of Instrument through controls on ePanel
![Page 11: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/11.jpg)
Chromatography Studio
• Used for All Data Evaluation • Provides access to every object in the sequence:
• Injection List • Instrument Method • Processing Method • Results • Report Template • Spectral Library
• Opens in separate window on task bar – makes working with multiple sequences easy
• Uses new “Ribbon” technology introduced in Microsoft Office 2007
![Page 12: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/12.jpg)
Chromatography Studio
Category Bars
Navigation Pane
Ribbon
![Page 13: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/13.jpg)
13
New Ribbon Interface
• Provides contextual access to commands and options in the Studio
13
![Page 14: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/14.jpg)
PEAK DETECTION COBRA™ Detection Algorithm / SmartPeaks™
![Page 15: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/15.jpg)
Peak Detection
• Most time consuming and tedious task in chromatography process:
• Chromatogram Integration
• Chromeleon 7 introduces two new tools to simplify this process:
• Cobra Peak Detection Algorithm / Wizard
• SmartPeaks Integration Assistant
![Page 16: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/16.jpg)
Peak Detection – Cobra
• Cobra is a new algorithm that:
• Finds peak start and end times accurately and consistently
• Requires minimum number of parameters to reach integration goals
• Cobra Wizard provides:
• Fast, guided way to determine initial detection parameters
![Page 17: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/17.jpg)
Peak Detection – Cobra Wizard
![Page 18: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/18.jpg)
Peak Detection – Cobra Wizard
Start Cobra Wizard
Define the integration range
Select the narrowest peak to be integrated
Select the smallest peak to be integrated
![Page 19: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/19.jpg)
Peak Detection – Cobra Wizard
19
And your integration is done!
![Page 20: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/20.jpg)
Peak Detection - SmartPeaks
• Unique tool for easily reaching your integration goals for unresolved peaks
• Requires no training
• Great example of Operational Simplicity • Process is clear and understandable • Requires only a few steps • Correctly integrates all unresolved peaks in seconds
![Page 21: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/21.jpg)
Peak Detection – SmartPeaks
21
Activate SmartPeaks Wizard
Select area of interest
Select the integration you want
![Page 22: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/22.jpg)
Peak Detection – SmartPeaks
22
And your integration is done!
![Page 23: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/23.jpg)
eWORKFLOWS™
The Ultimate in Operational Simplicity
![Page 24: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/24.jpg)
eWorkflows
• eWorkflows automate all chromatography processes
• Applies to all laboratories, for example: • QA/QC laboratories • Method development laboratories • Research & Development laboratories • Walk-up instrument workflows
• Takes you from Samples to Results in only a few steps
![Page 25: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/25.jpg)
eWorkflows
• An eWorkflow brings together all aspects of a chromatography run: • Instruments which are allowed to run this application • All associated files:
• Instrument Methods • Processing Methods • Reports • Spectral Libraries • Documents with description of method
• Template for sequence name and storage location • Custom Variables • Rules for sequence layout
![Page 26: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/26.jpg)
eWorkflows – A Regulated USP/EP Method
Choose eWorkflow, select instrument, and click “Start”
Enter number of samples, and start position
Sequence is created and can be immediately run
![Page 27: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/27.jpg)
eWorkflows – A Regulated USP/EP Method
• This eWorkflow also:
• Processes all data
• Calculates all results
![Page 28: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/28.jpg)
eWorkflows – From Samples to Results
• eWorkflows take you from Sample to Results in the minimum number of steps
• Fully customizable for any application
• Minimum amount of training required
• Reduces errors and produces results faster
• A new framework for Operational Simplicity
![Page 29: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/29.jpg)
INTERACTIVE CHARTING
![Page 30: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/30.jpg)
Data Visualization
• Interactive Charts for Data Visualization
• Fully customizeable • Templates for the most
common tasks • Available for both on-screen
and printed/exported reports.
![Page 31: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/31.jpg)
Interactive Charting
● Various Chart types
Pie Chart 2D / 3D
Stacked Column 2D / 3D
Scatter Plot
![Page 32: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/32.jpg)
Interactive Charting: Examples
Product Stability
Active Rel.Area % vs. Impurity Rel.Area %.
Query performed on SQL Server database on all data (including historical)
![Page 33: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/33.jpg)
Interactive Charting: Examples
33
Instrument Utilization
![Page 34: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/34.jpg)
Interactive Charting: Examples
34
Column Performance
![Page 35: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/35.jpg)
REPORTING
![Page 36: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/36.jpg)
Spreadsheet Based Reporting • The Excel-like report
environment is both familiar and intuitive.
• If Excel is used for additional calculations they can be included in Chromeleon.
• No data transcription or export to Excel is required.
• Results are generated instantly.
![Page 37: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/37.jpg)
Spreadsheet Based Reporting
Excel-like formulae can be included for custom
calculations
In this case the operator has configured a report to flag out of specification results.
![Page 38: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/38.jpg)
Report Designer - Functions
Many Excel-like functions available – use identical syntax
AVERAGE IF / AND / OR STDEV COUNT SUM LOOKUP etc……
![Page 39: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/39.jpg)
Report Designer – Export Options
1. TXT
2. PDF
3. XLS
![Page 40: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/40.jpg)
SUPPORT FOR THIRD PARTY INSTRUMENTS
![Page 41: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/41.jpg)
Instrument Control
• Chromeleon 7 can control Thermo Scientific LC, GC and IC.
• Chromeleon 7 can control 3rd Party LCs and GCs
• Agilent 1100, 1200, 1260, 1290, G1888, 6850, 6890, 7890
• Waters Acquity, Alliance • Shimadzu LC10, LC2010, LC20
• Chromeleon 6.8 controls over 330 different
modules from 30 different manufacturers. • These drivers are being converted to CM7
![Page 42: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/42.jpg)
Interfacing with 3rd Party Instruments
● Formal Code Exchange agreements with major manufacturers: ● Waters ● Agilent ● CTC ● Shimadzu
● For other manufacturers we rely on openly published codes ● e.g. GSIOC codes for Gilson systems
● For some manufacturers we provide a Driver Development Kit ● Merck Hitachi
42
![Page 43: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/43.jpg)
SUMMARY
![Page 44: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/44.jpg)
Chromeleon 7 – Simply Intelligent
• Contains the Intelligent Functionality needed to generate the result!
• Uses Operational Simplicity™ to minimize the steps and time needed to generate the result!
• Offers state-of-the-art technology: • User Interface with “Ribbon” • COBRA Peak Detection Algorithm & Wizard • SmartPeaks Integration Assistant • eWorkflows – THE framework for Operational Simplicity • Advanced Interactive Charting • Advanced Reporting
• Permits control of multiple vendors equipment from one application.
![Page 45: Chromeleon 7 Operational Simplicity for the Laboratoryapps.thermoscientific.com/.../CM7_Op_Simplicity_Somerset.pdf · 2011. 10. 17. · 7 - Operational Simplicity • Operational](https://reader036.vdocuments.us/reader036/viewer/2022071106/5fe0847f97c5136a9046a7eb/html5/thumbnails/45.jpg)
Chromeleon 7 – Simply Intelligent
Questions?