chemistry org/inorg 32 pp catalog for uk

Organic & Inorganic Chemistry

Access a World of New and Best-Selling Organic and Inorganic Chemistry Books & Products

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Reactions, Mechanisms, and Structure

7th Edition

March’s Advanced Organic Chemistry

Michael B. Smith

Organic ChemicalsIndustrial

HAROLD A. WITTCOFF • BRYAN G. REUBEN • JEFFREY S. PLOTKIN

THIRD EDITION

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NATALIA V. PLECHKOVA

KENNETH R. SEDDON

IonicLiquids

UNCOILEDCritical Expert Overviews

High Temperature Experiments in Chemistry and Materials Science

Ketil Motzfeldt

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Bioactive Heterocyclic Compound ClassesPharmaceuticals and Agrochemicals

TWO-VOlUmE SET

Clemens lamberth, Jürgen Dinges, Editors

Filling a gap in the market, this two-volume set is the first to present important developments in this area of chemistry as it relates to pharma-ceuticals and agrochemical pesticides. Each concise chapter covers one class of heterocycles and includes structural

formulas of important market products, characteristics of biologi-cal activity, structure-activity relationships, alternative syntheses, metabolic pathways, and more. It’s a handy one-stop reference for researchers in academia and industry, and for those with career aspi-rations in the field of pharmaceutical and agrochemical chemistry.

Hardcover 670 pp 2012 ISBN 978-3-527-32993-9 €229.00/£205.00/CAD $363.00/USD $330.00

Bioactive Heterocyclic Compound ClassesPharmaceuticals Jürgen Dinges, Clemens lamberth, Editors


Bioactive Heterocyclic Compound ClassesAgrochemicalsClemens lamberth, Jürgen Dinges, Editors


Spin-Crossover MaterialsProperties and Applicationsmalcolm A. Halcrow, Editor

Spin-Crossover Materials is your guide to recent developments in spin-crossover research, including the multidisciplinary nature of this rapidly expanding field. Here, editor Halcrow, an expert in the field, examines a wide range of topics including:

• Spin-crossover in mononuclear, polynuclear and polymeric complexes

• Structure: function relationships in molecular spin-crossover materials

• Charge-transfer-induced spin-transitions

• Reversible spin-pairing in crystalline organic radicals

• Spin-state switching in solution

• Spin-crossover compounds in multifunctional switchable materials and nanotechnology

• Physical and theoretical methods for studying spin-crossover materials.

A valuable resource for academic researchers working in the field of spin-crossover materials and also on topics related to crystal engi-neering, solid-state chemistry and physics, and molecular materials.


Malcolm A. HalcrowEDITOR

SPIN-CROSSOVER MATERIALSPROPERTIES AND APPLICATIONS

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Accelerate your research with access to Wiley Online Books in Organic Chemistry React ions, Pr inc ip les, and Techniques

P R A C T I C A L S Y N T H E T I C

O R G A N I C C H E M I S T R Y

E d i t e d b y

S t é p h a n e C a r o n

Editors Philip A. Gale and Jonathan W. Steed

Concepts

Techniques

Molecular Recognition

Supramolecular Catalysis, Reactivity and Chemical Biology

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Supramolecular Materials Chemistry

Soft Matter

Nanotechnology

SupramolecularChemistry From Molecules to Nanomaterials

1

Heterocyclic Chemistryat a GlanceSecond EditionJohn A. JouleKeith Mills

Enzyme Catalysis in Organic Synthesis Third, Completely Revised and Enlarged Edition

Edited by K. Drauz, H. Gröger, O. May

Volume 1

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GrapheneSynthesis, Properties, and PhenomenaC. n. R. Rao, Ajay K. Sood, Editors

Get quick access to a balanced overview of the fascinating molecule graphene and its potential applications in chem-istry, materials science, nanoscience, physics, and engineering.


GrapheneEdited by C. N. R. Rao and A. K. Sood

Synthesis, Properties, and Phenomena

Efficient Preparation of Fluorine CompoundsHerbert W. Roesky

Your definitive guide to creating fluorine-based compounds and the materials of tomorrow. Learn how to safely handle fluorine in the preparation of innovative new materials with valu-able new properties with this definitive manual to creating and understanding the reaction mechanisms integral to a wide variety of fluorine compounds. Coverage includes preparation of el-emental fluorine; synthesis methods for

exotic inorganic fluorides with varied applications; introduction of fluorine into compounds via electrophilic and nucleophilic reactions; direct fluorination of organic compounds with elemental fluorine; and more.


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Quinone MethidesS. E. Rokita

Quinone methides have cationic and anionic centers, providing an advanta-geous ability to react with both nucleo-philes and electrophiles. These reactive intermediates are of particular interest and have found wide applications in or-ganic synthesis. Featuring contributions from world-renowned leaders in the field, Quinone Methides covers a broad range of topics, including theoretical treatment, generation and detection of the intermediates, characterization, and

applications in chemistry and biochemistry (including biological reactivity).


Characterization of Solid Materials and Heterogeneous CatalystsTWO-VOlUmE SET

michel Che, Jacques C. Vedrine, Editors

This excellent handbook addresses everything there is to know about the many important characterization techniques covered. Clearly struc-tured into three parts according to the type of analytical technique, the chapters cover the most important parameters readers need to know in order to correctly interpret the spec-

tra, the experimental conditions, all the steps during the chemical reaction, and applications of the main catalysts. In addition, this ref-erence discusses the advantages and disadvantages of each specific technique, backed by experimental data and considerations, as well as specific application areas. It’s a must-have for everybody working in chemistry, analytics, materials science, and solid state physics.


Volume 1

Characterization of Solid Materials and Heterogeneous Catalysts

Edited by Michel Che and Jacques C. Védrine

From Structure to Surface Reactivity

The Chemistry of HeterocyclesTHiRD, COmplETEly REViSED AnD EnlARGED EDiTiOn

Theophil Eicher, Siegfried Hauptmann, Andreas Speicher

This classic is now completely revised and updated, with about 35 percent new content. The proven ordering system arranged in accor-dance with the ring size of the het-erocycles has been retained, while the important chapter, “Problems and their Solutions”, has been re-structured and enhanced with up-

to-date scientific exercises, resulting in a great tool for self-testing and exams. In addition, a new chapter on condensed heterocycles is included, as are a helpful index of name reactions and a chapter on nomenclature. With nearly 1,000 new literature citations, this remains a brilliant gateway to modern heterocyclic science.







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Chemistry of Love and Sexmadalena m. m. pinto

When the chemistry between two people is right, it’s right. But it may not be random. This book looks beyond romance to explore the chemical under-pinnings of what attracts one person to another, examining chemical phenom-ena and the molecules associated with endogenous hormonal mechanisms and brain neurotransmission—the basis of many emotions associated with love, passion, and sex. Chemistry of Love and

Sex demonstrates how these variables interact and play upon each other during varying phases of human relationships. External factors that may influence love and sex, such as pharmaceuticals, cosmetics, and food are also considered.

Paperback 120 pp 2013 ISBN 978-3-90639-068-0 €22.90/£18.99/CAD $37.95/USD $34.95

Chemistry of Love and Sex

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Microwaves in Organic SynthesisAntonio De la Hoz, André loupy, Editors

3RD EDiTiOn TWO-VOlUmE SET

Get coverage of everything you need to know about micro-wave technology for synthe-sis, from the best equipment to nonthermal effects, from solid-support reactions to catalysis. Completely revised and updated, with half of the authors completely new to the project, this comprehensive work is clearly divided into

four parts: fundamentals, methodology, combination of enabling technologies, and applications. Also new to this edition are chapters on on-line monitoring; flow chemistry; combination with ultrasounds and; natural products, including multicomponent reactions.


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Letters to a Young ChemistAbhik Ghosh, Editor

Letters to a Young Chemist for students and professionals alike opens a unique window into the real world of chemistry. Entertaining, informative, and full of hon-est and inspiring advice, it will serve as a helpful guide throughout your educa-tion and career. Written with a humor-ous touch by some of today’s leading chemists, this book presents missives to Angela, a fictional undergraduate consid-ering a career in chemistry. The different

chapters offer a mix of fundamental principles, contemporary issues, and challenges for the future.


Heterocyclic ChemistryFiFTH EDiTiOn

John A. Joule, Keith mills

This fifth edition of Heterocy-clic Chemistry maintains the principal objective of earlier editions: to teach the fundamen-tals of heterocyclic reactivity and synthesis in a way that is under-standable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate

courses and chemists at all levels working with heterocyclic com-pounds. This fully updated edition features extensive use of color to highlight changes in structure and bonding during reactions. It also contains new chapters and sections on heterocycles in medicine, isotopically labeled heterocycles, and solid-phase chemistry, among others.



Metals in MedicineJames C. Dabrowiak

Metals in Medicine explains the funda-mental chemical reasoning behind the action of metal-based drugs for treating and diagnosing disease. It examines the bonding concepts related to metallo-drugs, agents, and substances interac-tions, plus much more. The book also outlines the steps from drug discovery to the marketplace. Included is a supple-mentary website with downloadable

PowerPoint slides, feature boxes, references, bibliographies, and end-of-chapter problems and exercises.








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6

Metal-Organic FrameworksDesign and Applicationleonard R. macGillivray, Editor

Metal-organic frameworks represent a new class of materials that may solve the hydrogen storage problem associated with hydrogen-fueled vehicles. In this first definitive guide to metal-organic frame-work chemistry, explore state-of-the-art developments in this promising technology for alternative fuels. Providing professors, graduate and undergraduate students,

structural chemists, physical chemists, and chemical engineers with a historical perspective, as well as the most up-to-date develop-ments by leading experts, this must-have book examines structure, symmetry, supramolecular chemistry, surface engineering, metal-organometallic frameworks, properties, and reactions.


Mirror-Image AsymmetryAn Introduction to the Origin and Consequences of Chirality James p. Riehl

Written at an introductory level, Mirror-Image Asymmetry provides an overview of the importance and consequences of asymmetry from the atomic and molecular world of physics and chemistry to the or-ganisms and structures that we see in our macroscopic world. Rich with up-to-date examples and theories, the text’s numer-

ous drawings of chiral molecules help lend insight as to why nature may have selected on isomer over another and will inspire scientists in chemistry, biology, physics, and drug discovery in their syntheses of new compounds.


Design and Application

Edited by Leonard R. MacGillivray

Metal-Organic Frameworks

MIRROR-IMAGEASYMMETRY

James P. Riehl

A N I N T R O D U C T I O N T O T H E O R I G I N A N D C O N S E Q U E N C E S O F C H I R A L I T Y

The Group 13 Metals Aluminium, Gallium, Indium and ThalliumChemical Patterns and PeculiaritiesSimon Aldridge, Anthony J. Downs

This book provides an up-to-date review of group 13 metals. In effect, it is a much needed update of the seminal reference Chemistry of Aluminium, Gallium, Indium and Thallium, but differs in its greater preoc-cupation with the chemistry of the elements

and their compounds. The book covers new facts, developments, and applications in the context of more general patterns of physical and chemical behavior, particularly the main growth areas, including the chemistry of lower formal oxidation states, and cluster chemistry, among others.


Editors | SIMON ALDRIDGE | ANTHONY J. DOWNS

THE GROUP 13 METALS ALUMINIUM, GALLIUM, INDIUM AND THALLIUMChemical Patterns and Peculiarities

Nitrene and Nitrenium IonsDaniel E. Falvey, Anna D. Gudmundsdottir, Editors

VOlUmE Six

Explore the role of reactive interme-diate nitrene and nitrenium ions in chemistry and biochemistry, especially in DNA-damaging processes. A broad range of topics is covered, including ultrafast studies, computational studies, behavior in aqueous solution, electronic structures, and reactions with aromatic compounds. This valuable resource will empower you to better understand and expand their synthetic utility.


W I L E Y S E R I E S O N R E A C T I V E

I N T E R M E D I A T E S I N C H E M I S T R Y

A N D B I O L O G Y

Steven E. Rokita, Series Editor

NITRENE AND

NITRENIUM IONS

Edited by Daniel E. Falvey and Anna D. Gudmundsdottir

V O L U M E S I X

Metal-Organic FrameworksApplications from Catalysis to Gas StorageDavid Farrusseng, Editor

A must for every scientist in the field, this work was penned by an international and interdisciplinary team of leading experts from both academia and industry, who report on the wide range of hot applications for MOFs, discussing both the advantages and limits of the material. The resulting

overview covers everything from catalysis and H2 and CH4 storage and gas purification to drug delivery and sensors. A partial list of top-ics includes thermodynamic methods for prediction of gas separa-tion in flexible frameworks: separation and purification of gases by MOFs: the manufacture of MOF thin films on structured supports for separation and catalysis: the separation of xylene isomers: and much, much more.


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Pharmaceutical Process Chemistry for SynthesisRethinking the Routes to Scale-Uppeter J. Harrington

Expand your knowledge of process patents for “blockbuster” drugs. Providing insights about process route selection, choice of reagents, and reaction conditions, Pharma-ceutical Process Chemistry for Synthesis guides process chemists in identifying best

processes for manufacturing blockbuster drugs as they lose patent protection. Highlighting strategies and methodology useful for expe-diting research and development, the book also takes on a refresh-ingly objective perspective and is essential for process chemists.


Pharmaceutical Process Chemistry

for SynthesisR E T H I N K I N G T H E

R O U T E S T O S C A L E - U P

P e t e r J . H a r r i n g t o n





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Structural Methods in Molecular Inorganic ChemistryDavid Rankin, norbert mitzel, Carole morrison

Discover how you can better interpret experimental data, decipher the mate-rial published in modern journals of inorganic chemistry, and make sound decisions about what techniques will be the most useful in solving particular structural problems. Throughout this text, a strong connection is made

between theoretical topics and the real world of practicing chem-ists. Each chapter concludes with problems and discussion ques-tions. Following a general introduction to the tools and concepts in structural chemistry, topics include computational chemistry, nuclear magnetic resonance spectroscopy, electron paramagnetic resonance spectroscopy, and more. Case histories illustrate how chemists have applied a broad range of structural techniques to interpret and understand chemical systems.



INORGANICCHEMISTRYA WILEYTEXTBOOKSERIES

DAVID W. H. RANKINNORBERT W. MITZELCAROLE A. MORRISON

STRUCTURAL METHODS IN MOLECULARINORGANIC CHEMISTRY

Modern Methods in Stereoselective Aldol ReactionsRainer mahrwald, Editor

Take advantage of this ready refer-ence that provides a systematic over-view of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, includ-ing vinylogous Mukaiyama-aldol reactions and substrate-controlled

aldol reactions, as well as asymmetric induction in aldol additions. Furthermore, new developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. All of these methodologies are presented in the context of their deployment in the total synthesis of natural products.


Modern Methods in Stereoselective Aldol Reactions

Edited by Rainer MahrwaldnEW nEW

Aldrich® Chemistry and John Wiley & Sons are pleased to announce the winner of the EROS Best Reagent Award 2012

About the winner – Bruce H. LipshutzBruce Lipshutz has been at UC Santa Barbara since 1979. Much of his career has been focused on developing new reagents and technologies that have broad appeal in the synthetic community, many of which are now, or will soon be, commercially available. The group’s efforts have, in part, shifted with an emphasis on “green chemistry”. As winner of the EROS Best Reagent Award 2012, Bruce Lipshutz receives a $10,000 cheque and will present an EROS Award Lecture at Wayne State University, Detroit, USA in October 2012.

About the reagent[(R)-(-)-DTBM-SEGPHOS]CuH • [(S)-(+)-DTBM-SEGPHOS]CuH Aldrich Catalog: 762458/762938 • CAS: 566940-03-2/210169-40-7

The reagent is a catalyst which can be used in homogeneous or heterogeneous form and it has been applied to a number of copper-catalyzed asymmetric reductions, hydrosilylations, and reductive aldol reactions. The article on the Award winning reagent by Bruce H. Lipshutz and co-workers Danielle M. Nihan and Benjamin R. Taft was published in EROS in March 2009.

These reagents are available to purchase through Aldrich.com.

About the EROS Best Reagent AwardSponsored by Aldrich® Chemistry and John Wiley & Sons, the EROS Best Reagent Award was created to honour the work of the authors to the online edition of Encyclopedia of Reagents for Organic Synthesis [EROS and e-EROS] which launched in April 2001. Updated every year with around 200 new or updated articles, these contributions from carefully selected synthetic chemists ensure that this collection of reagents and catalysts remains a primary source of information for chemists at the bench.

Award Committee:David Crich, Wayne State University, USAPhilip Fuchs, Purdue University, USAAndré Charette, Université de Montréal, CanadaTomislav Rovis, Colorado State University, USALeo Paquette, Ohio State University, USAGary Molander, University of Pennsylvania, USAPeter Wipf, University of Pittsburgh, USA

For more information about EROS and the EROS Best Reagent Award visit wileyonlinelibrary.com/ref/eros

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8

Practical Microwave Synthesis for Organic ChemistsStrategies, Instruments, and ProtocolsC. Oliver Kappe, Doris Dallinger, Shaun murphree

The use of microwaves to control and speed up chemical reactions has within only a few years revolutionized the organic synthesis laboratory, because the instru-mentation is cheap and easily adapted to existing protocols. With just the right

level of detail for beginners, this book combines basic facts with tried-and-tested protocols, allowing quick mastery of the technique for chemists who don’t have the time to read through hundreds of pages of text before starting their first microwave experiment.

Hardcover 310 pp 2009 ISBN 978-3-527-32097-4 ˆ 65.00/£55.00/CAD $99.00/USD $90.00

Excel for ChemistsA Comprehensive Guide

THiRD EDiTiOn

E. Joseph Billo

“Excel for Chemists should be part of any aca-demic library offering courses and programs in chemistry. There is no other book on the market that deals so thoroughly with the application of Excel for analyzing chemical data.”—Choice

Chemists across all disciplines use Excel to record data in tabular form, but few have learned to take full advantage of the program. Featuring clear step-by-step instruction, Excel for Chemists shows how to use the scientific calculating power of Excel to perform a variety of chemical, biochemical, physical, en-gineering, biological, and medicinal calculations. Includes a CD-ROM for both Mac and Windows containing many useful spreadsheet templates, macros, and other tools.

Paperback w/CD-ROM 760 pp 2011 ISBN 978-0-470-38123-6 €53.90/£40.50/CAD $65.95/USD $59.95

THIRD EDITION

E. Joseph Billo

A Comprehensive Guide

EXCELfor Chemists

®

IncludesCD-ROM

Ordered Mesoporous MaterialsDongyuan Zhao, ying Wan, Wuzong Zhou

In an in-depth and systematic man-ner, this work outlines the step-by-step synthesis, synthesis mecha-nism, characterization, morphology control, hybridization, and applica-tions of mesoporous molecular sieves. In so doing, it also examines silicates, metal-doped silicates, non-silicates, and organic-inorganic hybrids. While the emphasis here is on synthesis, the authors also

discuss characterization and applications ranging from catalysis and biochemistry to optics and the use of ordered mesoporous materials as templates for nanomaterial synthesis. Both the fundamentals as well as the latest research results are covered, making this work a handy reference for researchers and newcomers to the field alike.


The Rare Earth ElementsFundamentals and ApplicationsDavid A. Atwood

Explore the the basic chemistry—particularly inorganic chemistry—of the lanthanoid elements. This work explores the similarity of the group 3 elements, Sc, Y, La, the group from which the lanthanoids originate, and the group 13 elements, particularly aluminum. Coverage also demon-strates how the lanthanoid elements relate to other, more common, ele-

ments in the periodic table. The occurrence and mineralogy of the el-ements, with a focus on structural features observed in compounds, is also explained. For convenience, the majority of the chapters are organized by the oxidation state of the elements, Ln(0), Ln(II), Ln(III), and Ln(IV). Part of the EIBC Book Series


Perspectives on Structure and Mechanism in Organic ChemistrySECOnD EDiTiOn

Felix A. Carroll

A must-have resource for that clearly explains the basic physical organic chemistry necessary to understand the synthetic applications. A definitive and easy-to-understand text for students and professionals in organic chemistry, this second edition is updated throughout with

modern concepts, revised references, and additional study questions to improve and guide student understanding. New topics include density functional theory, enhanced coverage of organometallic reagents, the effect of solvent on organic reactions, and much more.


Dongyuan Zhao, Ying Wan, and Wuzong Zhou

OrderedMesoporous Materials

Visit the online Encyclopedia of Inorganic and Bioinorganic Chemistry atwww.wileyonlinelibrary.com/ref/eibc

The Rare Earth Elements

EditorDavid A. Atwood

Fundamentals and Applications

FELIX A. CARROLL

Perspectives on

Structure and Mechanismin Organic Chemistry

S E C O N D E D I T I O N

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Asymmetric Synthesismathias Christmann, Stefan Bräse, Editors

Stay up to date on the latest developments in asymmetric synthesis and selected ap-plications in natural product synthesis, chemical industry, and materials science with cov-erage of a broad range of topics in all important areas, including metal catalysis, organocatalysis, physical organic chemistry, and analytical chemistry. Following a foreword by Nobel laureate E. J. Corey, the illustrious group of

international authors provides you with the latest research highlights.



Patent Strategy for Researchers and Research ManagersTHiRD EDiTiOn

H. Jackson Knight

Patent Strategy introduces researchers to patent applica-tions and patent portfolios. With minimum use of legal jargon, it provides the techni-cal professional with the assistance and advice they require to understand the legal complexities that they may encounter before and during a patent application. This updated edition was expanded to keep pace with recent

developments and addresses global issues surrounding intellectual property. Including new information on topics such as software and biotechnology, it covers techniques that can be used by readers to protect their work.

Hardcover 256 pp 2013 ISBN 978-0-470-05774-2 €77.90/£60.00/CAD $99.00/USD $90.00 Paperback 264 pp 2013 ISBN 978-0-470-05775-9 €35.90/£27.50/CAD $50.00/USD $45.00

for researchers and research Managers

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Patent strategy

tHird Edit ion

Introduction to Strategies for Organic Synthesislaurie S. Starkey

For those new to the field of organic synthesis, let this work be your guide. Introduction to the Strategies of Organic Syn-thesis covers the practical skills of making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. An excellent primer, it incorporates a review of each organic reaction before looking at the same reac-tion from a synthetic chemist’s

point of view. It’s written to help readers feel comfortable with the retrosynthetic analysis of a target molecule and aims to foment a secure understanding of organic chemistry reactions overall. Perfect as a text for graduate-level synthesis coursework and research or as a reference for those who need to refresh their knowledge of the subject.


Solvents and Solvent Effects in Organic ChemistryFOURTH EDiTiOn

Christian Reichardt, Thomas Welton

“. . . it is well worth the time of every organic chemist to read this book and learn how solvents influence the myriad phenomena of organic chemistry. It is also a superb refer-ence book . . . with the largest bib-liography on solvents and solvent effects . . . every practicing organic chemist should either own a copy or have access to one.”—R. Pagni, Journal of Chemical Education

Retaining its proven concept, the handbook is completely updated and contains 15 percent more content, including new chapters:

“Solvents and Green Chemistry,” “Classification of Solvents by Their Environmental Impact,” and “Ionic Liquids.” From the contents:

• Solute-Solvent Interactions

• Classification of Solvents

• Solvent Effects on the Position of Homogeneous Chemical Equilibria, on the Rate of Homogeneous Chemical Reactions, and on Absorption Spectra of Organic Compounds

• Empirical Parameters of Solvent Polarity.

Hardcover 718 pp 2011 ISBN 978-3-527-32473-6

€159.00/£130.00/CAD $253.00/USD $230.00

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10

Encyclopedia of Radicals in Chemistry, Biology and MaterialsFOUR-VOlUmE SET

Chryssostomos Chatgilialoglu, Armido Studer, Editors

In recent years, free radicals have come to play an important role in various disciplines, from organic synthesis to biology and medicine to materials science. And now, for the first time, this four-volume work examines free radicals within an interdisciplin-ary and multidisciplinary context, connecting structural character-

istics and chemical properties to their applications in different areas of chemistry and related disciplines. It covers not only basic concepts and chemical synthesis, but also touches on free radicals in materials and the life sciences. The reader will find a balanced offering of topics related to free radicals that cover, for example, their role in proteomics, genomics, and lipidomics as well as their enormous potential in syn-thesis and technology.


Ionic Interactions in Natural and Synthetic MacromoleculesAlberto Ciferri, Angelo perico, Editors

A comprehensive examination of ionic interactions in macro-molecules, this book addresses the conventional treatments of fixed charges, including screening and condensation by mobile ions. The interaction of ions with less polar sites on the macromolecule and the origin of the lyotropic are extensively addressed. Complex micellar organizations involving charged macromolecules (e.g., DNA) and

low-molecular-weight ampholytes and strong protein associations are covered. The contribution of electrostatic and hydrophobic interaction to the stability of proteins and other supramolecular structures are also analyzed, and there are chapters on applications such as deioniza-tion and cosmetic formulation.


Green Techniques for Organic Synthesis and Medicinal ChemistryWei Zhang, Berkeley Cue, Editors

Take advantage of this essential resource on green chemistry that presents an overview of the established and emerging tech-niques in green organic chemistry, highlighting their applications in medicinal chemistry. First you’re introduced to the toxicology of organic chemicals, their environ-mental impact, and the concept

of green chemistry before covering a variety of green catalytic tech-niques, including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Next, a series of new techniques assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise) and ap-plications of green chemistry concepts and special techniques for medicinal chemistry are covered.


GREEN TECHNIQUES FOR ORGANIC SYNTHESIS AND

MEDICINAL CHEMISTRY

EDITORS

WEI ZHANGBERKELEY W. CUE

Fieser and Fieser’s Reagents for Organic Synthesis Volumes 1-27, and Collective Index for Volumes 1-22, SetTse-lok Ho

‘”Highly recommended . . . lots of succinct, practical information on recent developments . . . in a format that is easy to use.“—Journal of the American Chemical Society, for the previous edition

The well-respected and ever-pop-ular Fieser and Fieser series on reagents for organic synthesis pro-vides concise descriptions, good structural formulas, and selected

examples of applications—providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references, and more. The reagents are consid-ered in alphabetical order by common usage names.

Each volume in the series is also available for separate purchase. For more information, visit us online at www.wiley.com.


€2790.00/£2167.00/CAD $3575.00/USD $3250.00

Fiesers’Reagents for

Organic Synthesis

VOLU ME 27

TSE-LOK HO







11

Molecular Orbitals and Organic Chemical ReactionsREFEREnCE EDiTiOn

ian Fleming

This new student edition serves, in a sense, as a second edition of the author’s influ-ential earlier book, Frontier Orbitals and Organic Chemical Reactions, but has been completely rewritten with much more on molecular orbital theory itself and on the effect of orbital interactions on the structures of organic molecules. There is also more on the theories behind hard and

soft acids and bases, and a whole chapter on the stereochemistry of fundamental organic reactions.


Molecular Orbitals and Organic Chemical ReactionsSTUDEnT EDiTiOn



Organic Synthesis Using Transition MetalsSECOnD EDiTiOn

Roderick Bates

Organic Synthesis Using Transition Metals, Second Edition, considers the ways in which transition metals, as catalysts and reagents, can be used in organic synthesis. It concentrates on the bond-forming reactions that set transition metal chemistry apart from classical organic chemistry. For this second edition, the text has been

extensively revised and expanded to reflect the significant improve-ments and advances in the field, as well as the large number of new transition metal-catalysed processes that have come to prominence in the last 10 years, the extraordinary progress in coupling reactions using designer ligands, catalysis using gold complexes, and C-H activation. Each chapter is extensively referenced and provides a convenient point of entry to the research literature.



ORGANIC SYNTHESISUSING TRANSITION METALS

Second Edition

Roderick Bates

Dynamic Combinatorial ChemistryJoost n. H. Reek, Sijbren Otto, Editors

DCC is a new and exciting topic in organic chemistry/supramolecular chemistry. The first book to explain the basis and applications of this promising discipline, Dynamic Combinatorial Chemistry gathers together a veritable who’s who of the field, covering catalyst, sensors, polymers, ligands, receptors—all in this one-stop reference that is suitable for organic chem-ists, catalytic chemists, polymer chemists,

biochemists, and physical chemists.


Organic SynthesesCollective Volume XIC. K. Zercher

A hands-on reference for professionals and students in organic and medicinal chemistry, this compilation of revised editions of Annual Volumes 80 through 84 continues the tradition of providing information on significant and interesting procedures with demonstrated utility in or-

ganic synthesis. Following precedent, there is no central theme, but the procedures can be organized into four categories: (1) asymmetric syntheses, chiral auxiliaries, and chiral ligands; (2) reactions that are promoted by metals or proceed via organometallic intermediates; (3) cycloaddition reactions; (4) valuable synthetic transformations and building blocks.


€159.00/£122.00/CAD $215.00/USD $195.00

Information Retrieval: SciFinder®

SECOnD EDiTiOn

Damon Ridley

This fully revised edition of the only companion guide to SciFinder gives practical advice on maximiz-ing one’s effectiveness with the program. It summarizes the various databases and explains how to take advantage of SciFinder’s unique search and analyze options, shows how to apply scientific method to information retrieval, and details how to search for chemical struc-

tures and chemical reactions. Essential for anyone who uses chemi-cal information in academic or industry, this latest edition addresses the major new release of SciFinder in 2008, which includes a Web interface for the first time.



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Hypercarbon ChemistrySECOnD EDiTiOn

George A. Olah, G. K. Surya prakash, Robert E. Williams, Kenneth Wade, Árpád molnár

Diminishing petroleum supplies, regulatory problems, and environmental concerns constantly challenge chemists to rethink and redesign the industrial applications of hydrocarbons. Edited by Nobel Prize win-ner George Olah and hydrocarbon expert Árpád Molnár, this completely revised and expanded second edition provides

an unparalleled contemporary assessment of the field, presenting basic concepts, current research, and future applications. It includes a new section on the chemical reduction of carbon dioxide—focus-ing on catalytic, ionic, electrocatalytic, photocatalytic, and ezymatic reductions— as well as a new chapter on new catalysts and activation methods, combinatorial chemistry, and environmental chemistry.



HYPERCARBONCHEMISTRY

George A. Olah

G. K. Surya Prakash

Robert E. Williams

Kenneth Wade

Árpád Molnár

Bioinorganic PhotochemistryGrazyna Stochel, Zofia Stasicka, malgorzata Brindell, Wojciech macyk, Konrad Szacilowski

Bioinorganic Photochemistry seeks to explain the interaction of select enzymes and proteins with light—most familiarly, photosynthesis—and presents a significant challenge to chemists in many areas. Bioin-organic Photochemistry offers a thorough overview of this important and exciting area of research, covering fundamental principles and concepts, and illustrating

the applications in biological, medical, and environmental science. Written as a go-to guide for all those involved in the investigation or development of bioinorganic photochemical processes, the book can also serve as a key text for advanced courses in inorganic chemistry.


Modern Heterocyclic ChemistryFOUR-VOlUmE SET

Julio Alvarez-Builla, Juan Jose Vaquero, José Barluenga, Editors

No doubt about it, this two-volume hand-book is the go-to reference for information pertaining to the huge field of heterocyclic compounds. An up-to-date source of high-quality information, it’s a must for everyone working in this field, whether in industry or academia. Including only the important

facts about each heterocyclic compound class, the handbook is more complete and easier to use than the various book series that cur-rently dominate the market, but still provides comprehensive cover-age of all aspects that a chemist needs to know: synthesis, structure, and chemical and physical properties.


€599.00/£490.00/CAD $743.00/USD $810.00

Organo Main Group ChemistryKin-ya Akiba

This vital resource book captures the essential scope of organic chemistry of all main group elements and cov-ers all main group elements dealing with syntheses and reactions of their organic compounds. While organic compounds of second row elements centered at carbon are the major components of animals and plants, those of the third row and below are also important and have unique roles, which this book discusses. Since main group chemistry has been traditionally

classified as a part of inorganic chemistry, this book establishes the scope of organic chemistry as it relates to main group elements.


Organo Main

Group Chemistry

K i n - y a A k i b a

Industrial Organic ChemicalsTHiRD EDiTiOn

Harold A. Wittcoff, Bryan G. Reuben, Jeffery S. plotkin

Learn how the majority of industrial organic chemicals and polymers are derived from seven major building blocks produced from petroleum and natural gas. You’ll get quick access to the chemistry of these building-block chemicals and their derivatives, and learn about how they are manufac-tured, as well as their uses and eco-nomic importance, and the associated

environmental concerns. The emergence of new companies such as INEOS, Formosa Plastics, LyondellBasell, and SABIC is covered, as is the growth of the chemical industry in China, India, the Middle East, and Russia. A new “Green” chapter that covers renewables, chemi-cals, and fuels is included.


Organic ChemicalsIndustrial

HAROLD A. WITTCOFF • BRYAN G. REUBEN • JEFFREY S. PLOTKIN

THIRD EDITION

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Ionic Liquids UnCOILedCritical Expert OverviewsKenneth R. Seddon, natalia V. plechkova, Editors

Ionic liquids are becoming widely rec-ognized as solvents for green synthesis because they have no measurable vapor pressure and show significant improve-ments in reaction rate, yield, and selec-tivity. Based on the work of prominent chemists from around the world, Ionic Liquids presents articles on topics at the forefront of ionic liquids research that represent a cross-section of the many

aspects of this burgeoning field. Topics covered are of academic and industrial interest, ranging from applied to theoretical, synthetic to analytical, in the fields of biotechnology, electrochemistry, process engineering, and nanotechnology.


Edited by

NATALIA V. PLECHKOVA

KENNETH R. SEDDON

IonicLiquids

UNCOILEDCritical Expert Overviews

Computational Organic ChemistrySteven m. Bachrach

This text introduces computational model-ing methods used as standard tools by organic chemists for finding, rationalizing, and predicting structure and reactivity of organic molecules. Moreover, it helps the reader develop a feel for the correct tool to use in the context of a typical problem in structure, activity, or reactivity. Topics discussed include simple molecular prop-erties, pericyclic reactions, carbenes and radicals, anion chemistry, solvent effects, and more.


Organometallic Compounds of Low-Coordinate Si, Ge, Sn and PbFrom Phantom Species to Stable CompoundsVladimir ya. lee, Akira Sekiguchi

Until recently, the low-coordinate com-pounds of the heavier elements of group 14 were known only as transient, unstable species that were difficult to isolate. Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb describes the chemistry of this exciting new class of organometallics, with an emphasis on

their major similarities and differences with the analogous species in organic chemistry. This book is an essential guide to this emerg-ing class of organometallic reagents for researchers and students in main group, organometallic, synthetic, and silicon chemistry.


VLADIMIR Ya. LEE | AKIRA SEKIGUCHI

From Phantom Species to Stable Compounds

Organometallic Compounds of Low-Coordinate Si, Ge, Sn and Pb

Making Chemistry RelevantStrategies for Including All Students in a Learner-Sensitive Classroom EnvironmentSharmistha Basu-Dutt, Editor

Stemming from a series of National Sci-ence Foundation grants and initiatives, this book presents a unique collection of strategies that are effective in chemistry classrooms. Featuring chapters from chemistry professors and research groups from a wide variety of research universi-ties, the book discusses chemistry con-cepts including environmental chemistry,

chemistry laboratory research, and forensics, among others. The cov-erage takes a cognitive constructivism approach, casting the teacher as a facilitator for students constructing solutions to problems.


Strategies for Including All Students in a

Learner-Sensitive Classroom

Environment

E D I T E D BY

S H A R M I ST H A BAS U - D U T T

MAKING CHEMISTRY RELEVANT

MAKING CHEMISTRY RELEVANT

Design and Strategy in Organic SynthesisStephen Hanessian, Simon Giroux, Bradley l. merner

This long-awaited textbook adopts a refreshingly unique approach and is writ-ten by one of the world’s leading organic chemists. Following an introductory look at the concept of synthesis, the text goes on to discuss sources of enantiomerically pure compounds, the Chiron approach, locating the various substructures, syn-

thesis with the various precursors, and computer-aided synthesis. The whole is rounded off by an appendix with selected transforma-tions of amino acids, carbohydrates, hydroxyacids, and terpenes. A must-have source of first-class information for everyone working in organic synthesis.



Design and Strategy in Organic Synthesis

Stephen Hanessian, Simon Giroux, and Bradley L. Merner

From the Chiron Approach to Catalysis

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14

Phosphorus(III) Ligands in Homogeneous CatalysisDesign and Synthesispaul C. J. Kamer, piet W. n. m. van leeuwen, Editors

Address the design and synthesis of a comprehensive compilation of P(III) ligands for homogeneous catalysis. You’ll not only focus on the well-known traditional ligands that have been explored by catalysis

researchers, but also promising ligand types that have traditionally been ignored mainly because of their challenging synthesis. Each ligand class is accompanied by detailed and reliable synthetic pro-cedures. Often the rate-limiting step in the application of ligands in catalysis is the synthesis of the ligands themselves, which can often be very challenging and time consuming.


Phosphorus(III) Ligandsin Homogeneous Catalysis

EditorsPaul C. J. KamerPiet W. N. M. van Leeuwen

Design and Synthesis

Applied Homogeneous CatalysisArno Behr, peter neubert

Adopting a didactic approach at an ad-vanced, master’s level, this concise textbook provides an array of questions and answers and features numerous industrial case stud-ies and examples, with references for further, more detailed reading and to the latest peer-reviewed articles at the end of each chapter. A significant feature is the book’s treatment of more recently developed catalytic pro-

cesses and their applications in the pharmaceutical and fine chemical industries, with an indication of their present and future commercial impact. Written by a dedicated lecturer with a wealth of experience in industry, this is an invaluable tool for practicing chemical engineers and chemists who need to advance their education in this vibrant and expanding field.


Organometallics in SynthesisTHiRD mAnUAl

manfred Schlosser

Your essential resource for all synthetic organic chemists. The content and topics covered are completely new to this edition, with an eye toward providing the most use-ful and practical reference on organometal-lics for practicing researchers. Background information about the organometallic class,

the various methods of preparing organometallic compounds, and their use in synthetic reactions are coupled with mechanistic consid-erations and future research opportunities for each organometallic class. Interspersed throughout are practical examples of the prepara-tion of organometallics, and their applications in organic synthesis are all thoroughly referenced.


Organometallics in SynthesisThird Manual

Edited ByManfred Schlosser

C

Fe

Pd

Si+Sn

Mg+Zn

Li+Na+K

Radionuclides in the EnvironmentDavid Atwood, Editor

Students, graduate students, research-ers, professionals, and environmentalists working in and with institutions creating radionuclides, such as nuclear power plants and nuclear medicine departments, will find this book to be of particular interest. With re-newed interest in radioactive elements due to recent discussions on nuclear power

plants and wide use of elements in nuclear medicine, this book is an important addition to the Encyclopedia of Inorganic Chem-istry, which so far has not covered radioactive elements. Contain-ing contributions by key experts, all the information is presented in a systematic style. Part of the EIBC Book Series


Biocatalysis and Biomolecular EngineeringChing T. Hou, Jei-Fu Shaw, Editors

Bringing together current advances and in-depth reviews of bio-based industrial products and agricultural biotechnology, Biocatalysis and Biomolecular Engineering examines the recent energy and food crises and points out the importance of using bio-based products from renewable resources and agricultural biotechnology. Exploring the use of most modern tools, such as

molecular engineering on plants, to solve these issues, as well as the methods employed, global experts show how development of the sustainable manufacturing industry is critical for the future wellness of our planet.


Innovative Catalysis in Organic SynthesisOxidation, Hydrogenation, and C-X Bond Forming Reactionspher G. Andersson, Editor

Authored by a European team of experts, this book compiles innovative approaches for C-X bond forming processes frequently applied in organic synthesis. It covers all key types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as

well as mechanistic and computational studies. Special attention is focused on the improvement of efficiency and sustainability of im-portant catalytic processes, such as selective oxidations, hydrogena-tion, and cross-coupling reactions. The result is a valuable resource for both advanced researchers in academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds using novel catalytic systems.


Innovative Catalysis in Organic Synthesis

Edited by Pher G. Andersson

Oxidation, Hydrogenation, and C-X Bond Forming Reactions

Radionuclidesin the Environment

EditorDavid A. Atwood

Visit the online Encyclopedia of Inorganic Chemistry atwww.mrw.interscience.wiley.com/eic/ EIC Books

Edited by

CHING T. HOUJEI-FU SHAW

Biocatalysisand

BiomolecularEngineering

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Practical Synthetic Organic ChemistryReactions, Principles, and TechniquesStéphane Caron, Editor

A must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields, Practical Synthetic Organic Chemistry provides the user with practical knowledge to assist in the planning and execution of synthetic reactions in the laboratory. Organized classically by

reaction type, the work selects the most reliable and useful reactions and provides the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. The text provides information on the basics of the reaction, the syn-thetic procedure(s), mechanism, and scope of the reaction.


MacrocyclesConstruction, Chemistry and Nanotechnology ApplicationsFrank Davis, Séamus Higson

Macrocycles is an essential introduction to this important class of molecules, covering their synthesis, their chemistry, how they can be used as nanotechnology building blocks, and their applications. A wide range of structures synthesized over the past few

decades are noted, from the simpler cyclophanes and multi-ring aromatic structures to vases, bowls, cages, and more complex multi-ring systems and 3D architectures such as pumpkins, interlocking chains, and knots. Some of the molecular classes covered include simple ring compounds, three-dimensional aliphatic carbon struc-tures, annulenes, multi-ring aromatic structures, porphyrins and phthalocyanines, cyclophanes, crown ethers, cryptands, spherands, and many more.



React ions, Pr inc ip les, and Techniques

P R A C T I C A L S Y N T H E T I C

O R G A N I C C H E M I S T R Y

E d i t e d b y

S t é p h a n e C a r o n

MacrocyclesConstruction, Chemistry and Nanotechnology Applications

FRANK DAVIS | SEAMUS HIGSON

The Power of Functional Resins in Organic SynthesisFernando Albericio, Judit Tulla-puche, Editors

Since work-up procedures in industry are both time- and energy-consuming processes, the interest in solid phases for industrial pur-poses is very high. For this reason, fast and simple synthesis has become a major focus of research over the last few years. While many books cover solid phase synthesis and

combinatorial synthesis, this guide is unique in exclusively covering the other aspects of solid-phase synthesis. As such, it covers virtually everything you need to know—from supported reagents to scaven-gers resins, and the synthesis of natural products.


Biomimetic Organic SynthesisTWO-VOlUmE SET

Erwan poupon, Bastien nay, Editors

As biomimetic organic synthesis gains in recognition, practioners will need to learn central key definitions, general concepts, and strategies. Here, natural product synthe-sis is classified according to main biosyn-thetic pathways (i.e., terpenes, alkaloids, polyketides) and the focus is on biomemtic efforts towards the total synthesis of natural

products. Biomimetic Organic Synthesis covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry. A first-of-its-kind, this two-volume set will help you devise clear strategies and utilize them as everyday tools. A timely reference for a topic on the forefront of organic science.

Hardcover 1024 pp 2011 ISBN 978-3-527-32580-1 €349.00//£285.00/CAD $517.00/USD $470.00

Solid-Phase Organic SynthesisConcepts, Strategies, and Applicationspatrick H. Toy, yulin lam, Editors

You’ll get a thorough overview of the field of solid-phase organic synthesis. Coverage focuses on fundamentals of heteroge-neous supports in the synthesis of organic molecules and explains the use of a solid material to support and thereby facilitate organic synthesis. Chapters are divided into two sections; the first introduces some

general concepts and strategies, while the second presents specific examples of the solid-phase synthesis of various classes of organic molecules.


Molecular EncapsulationOrganic Reactions in Constrained SystemsUdo H. Brinker, Jean-luc mieusset, Editors

The inclusion of small guest molecules within suitable host compounds results in constrained systems that imbue novel properties upon the incarcerated organic substrates. Supramolecular tactics are becoming widely employed and this treatise spotlights them. Often, the impact of encap-sulation on product formation is substantial.

The use of constrained systems offers the means to steer reactions along desired pathways. A broad overview of various supramolecu-lar approaches aimed to manipulate chemical reactions are featured.


Organic Reactions in Constrained Systems

EDITORS | UDO H. BRINKER | JEAN-LUC MIEUSSET

MOLECULAR ENCAPSULATION









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EsterificationMethods, Reactions, and Applications

SECOnD EDiTiOn

Junzo Otera, Joji nishikido

“. . . Otera’s book does a good job, concisely covering the esterification methodology literature from 1990 to 1999, and that survey will be useful to synthetic organic chemists. . . .”

—Angewandte Chemie

Bringing together articles and information spread throughout journals, magazines, and the like, this text is your convenient, one-stop guide to this very important

chemical reaction. Following an apt introduction, the book goes on to discuss methodology before addressing synthetic and industrial applications—the latter being a new focus in this completely revised, updated, and extended second edition. The value of this handy refer-ence is further enhanced by an accompanying CD-ROM database. A must-have tome for organic, natural products, and catalytic chemists, as well as those working in industry, of for lecturers in chemistry.


€149.00/£130.00/CAD $237.00/USD $215.00

Organic Chemistry—Breakthroughs and PerspectivesKuiling Ding, li-xin Dai, Editors

Get a top-notch, compact overview of the most important develop-ments organic chemistry has seen over the last ten years. You’ll survey, in one complete, self-con-tained volume, the major develop-ments in both established fields as well as totally new areas, with topics ranging from catalysis and total synthesis of natural products to C-H activation, organocatalysis,

supramolecular chemistry, and more. Bringing together contribu-tions from an international group of leading experts, it includes personal commentaries in each chapter with authors providing important insight into their own research.



Volume 1

Organic Chemistry – Breakthroughs and Perspectives

Edited by Kuiling Ding and Li-Xin DaiPractical Methods for Biocatalysis and Biotransformations 2 John Whittall, peter Sutton, Editors

Practical Methods for Biocatalysis and Biotransformations, Volume 2, focuses on the practical applications of enzymes and strains of microorganisms that are readily obtained or derived from culture collec-tions. The sources of starting materials and reagents, hints, tips, and safety advice (where appropriate) are given to ensure, as far as possible, that the procedures are

reproducible. Comparisons to alternative methodology are given, and relevant references to the primary literature are cited. This second volume concentrates on new techniques and new enzyme families that have been reported since the first. Up-to-date protocols and industry examples are used to describe the function of biocata-lysts in cutting-edge applications developed by leading academic and industrial research groups.


Biocatalysis and Biotransformations 2

Practical Methods for

Editors John Whittall | PEtEr W. Sutton

Steroid Chemistry at a GlanceDaniel lednicer

When most people hear the word “steroid,” they think of the type abused in sports. But those steroids comprise only a single small portion of a large collection of compounds found throughout legal, commercially avail-able drugs. Based on the highly successful and reader-friendly at-a-glance approach—integrated, self-contained double-page spreads of text and illustrations—this information-packed book delivers a concise

overview of the main principles and reactions of steroid chemistry. It includes history, nomenclature, properties, natural sources, synthe-sis, and so much more.



SteroidChemistryat a GlanceDaniel Lednicer

Boronic AcidsPreparation and Applications in Organic Synthesis, Medicine, and Materials

SECOnD EDiTiOn TWO VOlUmE SET

Dennis G. Hall, Editor

“. . . this excellent book deserves to be on the bookshelf of all synthetic chemists, whether in discovery or process chemistry.”—Organic Process Research & Development Journal

Following the huge success of the first edition, this completely updated edition is expanded by almost 50 percent. The world-renowned chemistry professor Dennis Hall is joined by a group of top authors to cover all modern aspects of boronic acid derivatives in one comprehensive handbook.


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Organic ReactionsVOlUmE 78

Scott E. Denmark

Your comprehensive resource on organic reactions, written by world-renowned ex-perts with extensive hands-on experience in the field. Each reaction is fully refer-enced to the primary literature, and tables containing all possible examples of the reactions under consideration are included.


Volume 79Hardcover 688 pp 2013 ISBN 978-1-118-50941-8

€129.00/£100.00/CAD $164.95/USD $149.95

Volume 80Hardcover 544 pp 2013 ISBN 978-1-118-51308-8

€129.00/£100.00/CAD $164.95/USD $149.95

ORGANIC

REACTIONS

Editors

BITTMAN

BOGER

CHARETTE

DENMARK

FARINA

HERGENROTHER

JOHNSON

MARTINELLI

McCOMBIE

MONTGOMERY

PHILLIPS

J. PRESS

L. PRESS

ROVIS

WEINREB

WIPF

Volume 78

Drug TruthsDispelling the Myths About Pharma R&DJohn l. lamattina

“An insider’s account of the reality of the drug discovery process—revealing it to be more risky, complicated and expensive than many critics sug-gest. Chapter by chapter, LaMattina addresses the common misconceptions about the pharmaceutical industry—setting the record straight.”— Kansas City InfoZine

“Along with a careful dissection of each false claim and a presentation of the overwhelming evidence that disproves it, LaMattina offers fascinating explanations of the way drug development and government approval function—relying not on clever rhetoric, but on scientific fact and reliable evidence to support his claims; all the while remaining realistic about the industry’s limitations.”—Medical News Today


Catalysismatthias Beller, Albert Renken, Rutger A. van Santen, Editors

Covers all the essential principles and makes use of case studies to illustrate the importance of catalysts in the chemical industry. The authors are all top-flight, with expertise in science, writing, and in teaching. And here they deliver an instructive, future-oriented work that is decidedly application-oriented. Among the many topics explored:

catalysis in perspective, concepts and methods, the chemistry of catalytic reactivity, catalytic conversions, catalyst synthesis and materials, experimental methods, reactor devices and operation, the design of catalytic systems/processes, and future perspectives.


CatalysisEdited by Matthias Beller, Albert Renken and Rutger A. van Santen

From Principles to Applications

Progress in Inorganic Chemistry VOlUmE 57

Kenneth D. Karlin, Editor

“This series is distinguished not only by its scope and breadth, but also by the depth and quality of the reviews.”

—Journal of the American Chemical Society

This acclaimed series from Wiley affords inorganic chemists and materials scientists a forum for critical, authoritative evaluations of advances in every area of the disci-pline. Volume 57 continues to report recent advances with a significant,

up-to-date selection of contributions from internationally recognized researchers. The chapters of this volume are devoted to the follow-ing topics: mechanisms of water oxidation catalyzed by ruthenium coordination complexes; biomimetic and nonbiological dinuclear Mx+-complex catalyzed alcoholysis reactions of phosphoryl transfer reactions; photoactivated DNA cleavage and anticancer activity of 3d-metal complexes; and more.


Modern Tools for the Synthesis of Complex Bioactive Molecules Janine Cossy, Stellios Arseniyadis, Editors

An overview of the new technolo-gies that have revolutionized organic chemistry and allowed easy access to complex bioactives, this book brings modern synthetic techniques and bioactives together. The synthesis of structurally complex molecules has become a real challenge for the syn-thetics community. The development of innovative methodologies enabling control of the exact connectivity of

the atoms within a molecule and setting correct three-dimensional arrangements are of particular interest for these practitioners. Combining representative experimental procedures for particular methods, this book explores this exciting field and addresses the latest technical developments.


MODERN TOOLSFOR THE

SYNTHESIS OF COMPLEXBIOACTIVE MOLECULES

Edited by

JANINE COSSY AND STELLIOS ARSENIYADISWith a Foreword by Nobel Laureate EI-ICHI NEGISHI

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Inorganic ExperimentsTHiRD EDiTiOn

J. Derek Woollins, Editor

Modern spectroscopic techniques and current research topics make this an incomparable resource for undergradu-ate and graduate students, presenting a fascinating approach to inorganic chemistry by providing experiments that resemble real research. As a result, students learn to think in a research-ori-ented fashion and to research together in a group. The experiments have been

thoroughly tested and safety instructions are included, while hazard-ous substances are replaced by less harmful ones. This new edition also has a special focus on environmentally friendly experiments.


Electron Flow in Organic ChemistryA Decision-Based Guide to Organic Mechanisms

SECOnD EDiTiOn

paul H. Scudder

Take advantage of a chemistry text that contains an array of useful tools rarely offered to undergraduates. Electron Flow in Organic Chemistry contains flow charts you can use as decision maps, correlation matrices that show all possible interactions, examples of simplified energy surfaces that can

be used as problem space maps, and more. All of which will help you develop a knack for organic chemistry, elevate your ability to approach and solve complex problems, and tackle methods of analysis that are valuable in and portable to other fields. This revised second edition builds on and improves the legacy of the first edi-tion’s unique decision-based approach to teaching/learning organic chemistry.

Paperback 448 pp 2013 ISBN 978-0-470-63804-0 €43.90/£33.50/CAD $54.95/USD $49.95Microgel SuspensionsFundamentals and ApplicationsAlberto Fernandez-nieves, Hans Wyss, Johan mattsson, David A. Weitz, Editors

Providing a vital link between chemistry and physics on the nanoscale, this book offers concise coverage of the entire topic in five major sections, beginning with synthesis of microgel particles and con-tinuing with their physical properties. The phase behavior and dynamics of resulting

microgel suspensions feature in the third section, followed by their mechanical properties. It concludes with detailed accounts of numer-ous industrial, commercial, and medical applications.


Chemistry and Biology of Artificial Nucleic Acidsmartin Egli, piet Herdewijn, Editors

The nucleic acid structure, as originally de-fined by the Watson-Crick double helix, has been expanded into an entire landscape of new structures adopted by artificial pairing systems. Countless strategies have been developed for the chemical synthesis of these modified nucleic acids. There is hardly another area in bioorganic chemis-try that has contributed so much to biology

throughout the last decades. This book combines the contributions of many of the major players in this research field, and covers the synthesis of sugar-, base-, and backbone-modified nucleic acids, their structural characteristics studied by X-ray crystallography, and NMR in solution as well as their chemical and biological properties.


Chemistry and Biology of Artificial Nucleic Acids

Martin Egli, Piet Herdewijn (Eds.)

Zeolites and CatalysisSynthesis, Reactions and ApplicationsJiri Cejka, Avelino Corma, Stacey Zones, Editors

This indispensable two-volume handbook covers everything on this hot research field. The first part deals with the synthesis, modification, characterization, and ap-plication of catalytic active zeolites, while the second focuses on such reaction types as cracking, hydrocracking, isomerization,

reforming, and other industrially important topics. Edited by a highly experienced and internationally renowned team with chapters writ-ten by the who’s who of zeolite research.


Zeolites and Catalysis Synthesis, Reactions and Applications

Edited by Jirí Cejka, Avelino Corma, and Stacey Zones

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PAUL H. SCUDDER

SECOND EDIT ION

ELECTRON FLOW IN ORGANIC CHEMISTRY

A DECISION-BASED GUIDE TO ORGANIC MECHANISMS

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19

Green Chemistry in the Pharmaceutical Industrypeter Dunn, Andrew Wells, michael T. Williams, Editors

Edited by three of the world’s leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all as-pects of green chemistry in the pharma-ceutical industry, from simple molecules to complex proteins, and from drug dis-covery to the fate of pharmaceuticals in

the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin, and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally friendly processes.


Steroid DimersChemistry and Applications in Drug Design and DeliverySatyajit Sarker, lutfun nahar

Keep up to speed with this overview of the chemistry and applications of steroid dimers of natural and synthetic origins. You’ll get easy-to-follow synthetic protocols for various classes of important dimeric ste-roids, source details, valuable spectroscop-ic data and depiction of unique structural features of natural steroidal dimers, and

the structure-activity-relationships (SARs) of some pharmacologi-cally active dimeric steroids. Topics covered include introduction to steroid dimers, synthesis and chemistry of noncyclic and cyclic ste-roid dimers, and naturally occurring steroid dimers (cephalostatins, ritterazines and crellastatins, and more).


Steroid DimersChemistry and Applications in Drug Design and Delivery

Lutfun Nahar | Satyajit D. Sarker

ChemosensorsPrinciples, Strategies, and ApplicationsBinghe Wang, Eric V. Anslyn, Editors

Chemosensors—organic molecules de-signed to bind and sense small molecules or metal ions—function as molecular-level sensors that generate a signal upon bind-ing. Chemosensors: Principles, Strategies, and Applications compiles information on sensor design in a single, accessible source.

It provides a comprehensive background on chemosensors and their synthesis, design, and applications for detecting biological and metal molecules. The text highlights applications in drug discovery and catalysis that have not been as well-covered elsewhere, making this an indispensable source of information.


Green Chemistry and CatalysisRoger A. Sheldon, isabel Arends, Ulf Hanefeld

“This book is the clear choice for any chemi-cal professional or graduate student seri-ously interested in the emerging field of green chemistry.”—Journal of the American Chemical Society

The first book to focus on catalytic processes from the viewpoint of green chemistry! Written by Roger A. Sheldon and his coworkers, this is an indispensable

resource for scientists looking to improve catalysis in both college and industry.


Wiley Series in Drug Discovery and Development Binghe Wang, Series Editor

Edited by Binghe Wang and Eric V. Anslyn

Rare Earth Coordination ChemistryFundamentals and ApplicationsChun-Hui Huang

Although several books have been published in this field, there is not an advanced book focusing on coordination chemistry with systematic introduction of basic knowledge, application technology, and the latest devel-opments. With this book, readers will gain proficiencies in systematic basic aspects and the latest development of applications of rare

earth coordination chemistry.


Name Reactions in Heterocyclic Chemistry IIJie Jack li, Editor

“. . . is not only an indispensable resource for senior undergraduate and graduate students . . . but also a good reference for all chemists interested in the chemistry of heterocyclic com-pounds. . . .”—Drug Development and Industrial Pharmacy, for the first edition

“. . . a major contribution to the field and is highly recommended.” —Journal of Medicinal Chemistry, for the first edition

Coauthored by Nobel laureate, E. J. Corey, this edition builds on the first, updating previous reactions or adding new three-, four-, five-, and six-membered heterocycles. Each section includes a description of the reaction, the historical perspective, a mechanism for the reac-tion, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and references to the current primary literature.


Wiley Series on Comprehensive Name ReactionsJie Jack Li, Series Editor

JIE JACK LI

Edited by

JIE JACK LI

NAME REACTIONS

inin

NAME REACTIONS

HETEROCYCLIC CHEMISTRY II

FOREWORD BY E. J. COREY








20

Molecular SwitchesSECOnD EDiTiOn, TWO-VOlUmE SET

Ben l. Feringa, Wesley R. Browne, Editors

“. . . a comprehensive and up-to-date insight . . .” —Chemistry & Industry for the first edition

Covering principles and applica-tions, this highly acclaimed book brings you everything you need to know about molecular switches: a hot topic in the nano world. The major classes of molecular switch-es, including catenanes, rotaxanes,

and azobenzenes, together with polymer and biomolecular switching systems and DNA-based switches, are covered. Completely revised and expanded to cover the very latest advance and developments, this handbook will benefit all readers interested in one of the most innovative areas in chemistry today.


Encyclopedia of Inorganic ChemistryFiVE-VOlUmE SET

Robert A. Scott

This five-volume set comprises the latest developments in the field and adds new topics and broadens the scope of the existing Encyclopedia. The first volume surveys the physical methods used to characterize inorganic compounds and materials. The second volume addresses the hot-topic area of inorganic nanomaterials. The third focuses on computational methods used in inorganic, and especially in bioinorganic chemistry. The fourth volume adds the dimension of radiochemistry and especially considers the fate of radionuclides in the environment. And the fifth volume concentrates on inorganic chemistry as a basic science for the technological development of new fuel cells and batteries. Each volume in the set is also available for independent purchase.


March’s Advanced Organic ChemistryReactions, Mechanisms, and Structure

SEVEnTH EDiTiOn

michael B. Smith

The definitive resource for students and professionals in the field, the seventh edition of March’s Advanced Organic Chemistry endures as a must-have resource for the planning and execution of synthetic reactions. Each chapter has been updated to reflect the most recent reaction information, with references to both

the primary and review literature. Heavily revised throughout, this edition brings this exemplary guide right up to the present. It clearly explains the theories and examples relating to hundreds of new reac-tions, covering each in clear detail.


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Reactions, Mechanisms, and Structure

7th Edition

March’s Advanced Organic Chemistry

Michael B. Smith






21

GalectinsAnatole A. Klyosov, Zbigniew J. Witczak, David platt, Editors

Following a general introduction to the subject, this first-of-its-kind text covers galectins’ structure and functions, li-gand specificity, and molecular mecha-nisms of action, along with the other roles galectins play in tumor growth and cancer, fibrosis, inflammation, and immunity. It then examines the effect galectins have on cell migration, an-giogenesis, and chemoresistance, and describes new approaches to designing galectin inhibitors.


Handbook of Reagents for Organic SynthesisReagents for Silicon-Mediated Organic Synthesisphilip l. Fuchs, Editor

Over the last three decades the impor-tance of organosilicon chemistry has opened a number of new synthetic strategies. This is the first handbook to compile essential silicon-containing reagents and make use of the leading reagent database e-EROS. The book’s

focus is on three key synthetic approaches with the greatest impact: use of silicon as a “temporary tether” by unifying a reactive pair of functional groups and taking advantage of their template-biased intramolecular cyclization; the specific use of the silane functional-ity as a hetero t-butyl group, sometimes referred to as the use a “fat proton”; and the use of the Brook rearrangement as an “anion relay stratagem.”


To see the complete collection of organic reagents online visit:

www.wileyonlinelibrary.com/ref/eros

Handbook of Reagents for Organic Synthesis

Reagents forSilicon-MediatedOrganic Synthesis

Edited by Philip L. Fuchs

Organic Chemistry I as a Second Language™Translating the Basic Concepts

SECOnD EDiTiOn

David R. Klein

An excellent guide to the subject that helps readers better understand fundamental principles, solve problems, and focus on what they need to know to succeed.


Dynamic Combinatorial Chemistry In Drug Discovery, Bioorganic Chemistry, and Materials Science Benjamin l. miller, Editor

This is your single-source reference for building structure libraries and design-ing compounds. You are presented an overview of dynamic combinatorial chemistry (DCC) and fragment-based library methods and how to apply them to the problems of lead generation for drug discovery and molecular recogni-

tion. Chapters cover basic theory, approaches to binding in proteins and small molecules, molecular recognition, catalyst discovery, click chemistry, SAR by NMR, and analytical chemistry challenges.


Modern Gold Catalyzed SynthesisA. Stephen K. Hashmi, F. Dean Toste, Editors

With its impressive features, gold has added another facet to organic catalysis. Focusing on homogeneous catalysis, this book also covers the main ap-plications in heterogeneous catalysis. Following a look at the gold-catalyzed addition of heteroatom nucleophiles to alkynes, this monograph goes on to dis-cuss gold-catalyzed additions to allenes

and alkenes, gold-catalyzed benzannulations, and cycloisomerization and rearrangement reactions, as well as oxidation and reduction reactions. The whole is finished off with a section on gold-catalyzed aldol and related reactions and the application of gold-catalyzed reactions to natural product synthesis.


Modern Gold Catalyzed Synthesis

Edited by A. Stephen K. Hashmiand Dean F. Toste


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22

Chemical BiologyLearning through Case StudiesHerbert Waldmann, petra Janning, Editors

“The approach taken by the editors is straightforward and easy to compre-hend, since the methods and tech-niques are introduced by examples from actual research projects.”

—Angewandte Chemie

For those with a penchant for hands-on learning, this first book to adopt a problem-based approach to chemical biology teaches the true

basics of the subject by way of illustrated everyday case studies. The editors’ extensive experience in writing textbooks and their close relationships to the authors ensure that the contributions here are presented in a uniform and highly motivating fashion. Each chapter introduces a different biological problem taken from everyday lab work, so that readers learn how to think for themselves in order to solve problems in biology by using powerful techniques and tools taken from actual practice.


Organic Crystal EngineeringFrontiers in Crystal EngineeringEdward R. T. Tiekink, Editor

Organic Crystal Engineering reviews of topics in organic crystal engineering that will be of interest to all researchers in molecular solid-state chemistry. Special-ist reviews, written by internationally recognized researchers, drawn from both academia and industry, cover topics including crystal structure prediction features, polymorphism, reactions in the solid-state, designing new arrays, and

delineating prominent intermolecular forces for important organic molecules.


Modeling of Molecular Propertiespeter Comba, Editor

With its comprehensive coverage of important research fields in molecular and materials science, this comprehen-sive guide to molecular modeling is a must-have for all organic, inorganic, and anyone interested in applied theoretical and computational chemistry. It covers methods for small chemical to large biological molecules and materials. The 28 chapters, written by an international

group of experienced theoretically oriented chemists, are grouped into four parts: Theory and Concepts; Applications in Homogeneous Catalysis; Applications in Pharmaceutical and Biological Chemis-try; and Applications in Main Group, Organic, and Organometallic Chemistry. The various chapters include concept papers, tutorials, and research reports.


Cumulenes in Click ReactionsHenri Ulrich

Cumulenes in Click Reactions presents a comprehensive list of cumulene systems and their reactions, with an emphasis on their “click-like” nature. Following an in-troduction to the chemistry of cumulenes, the chapters are structured according to the number of carbon atoms in the system. Written by a well-known expert in the field, Cumulenes in Click Reactions is an essential guide for researchers and advanced students in academia and

research working in synthetic organic, inorganic, and bioorganic chemistry.


Ionic Liquids in Biotransformations and OrganocatalysisSolvents and Beyondpablo Domínguez de maría

Ionic Liquids in Biotransformations and Organocatalysis is the first book to provide a multidisciplinary approach and overview of the fundamentals of ionic liquids and their interaction with proteins in diverse applications such as paint additives, reactive gas trans-port, nanomaterials synthesis, and hydrogen storage. It also examines

the different roles that ionic liquids can play: as solvents used to dis-solve other compounds; as co-catalysts in reactions to help increase product yield; or as additives to help create desired properties in various chemical products. Moreover, this book lays the foundation and demonstrates the potential of this technology through the inclu-sion of examples in every chapter.









23

Experiments in Green and Sustainable ChemistryHerbert W. Roesky, Dietmar Kennepohl, Editors

“Herbert Roesky has done us and the international chemistry community a big favor by translating his latest contribution in this area into English.”

—Angewandte Chemie International Edition

Written by the author of the award-winning Chemische Kabinettstücke, this book demonstrates more than 80 enjoyable, impressive, and some-times almost unbelievable chemical

experiments for the classroom, lecture hall, or home. Every experi-ment is explained in full and has been tested several times such that the successful reproduction is guaranteed. Grouped into several cycles—water, the color blue, the color red, soles, and self-organi-zation—the topics are perfect for experimental lectures or school projects. Detailed illustrations and the lively writing style make this book attractive to every reader interested in chemistry, leaving you spellbound and educated at the same time.


The Chemist’s Companion Guide to Patent LawChris p. miller, mark J. Evans

Written by an individual with experience as both a chemist and a patent attorney, The Chemist’s Companion Guide to Patent Law covers everything the student or working chemist needs to know about patentability, explaining important concepts of patent law (such as novelty, nonobviousness, and freedom-to-operate) in easy-to-understand terms. Through abun-dant examples taken from case law as well as real-world situations with

which a researcher might be faced, this book provides readers with a better understanding of how to protect the value of their findings.


New Strategies in Chemical Synthesis and CatalysisBruno pignataro, Editor

Penned by the most talented young chemists in Europe, this engaging work takes readers to the forefront of discovery as it tackles today’s frontier issues in materials science, nanosci-ence, and chemistry. Covers the most recent results of European research in areas including the self-assembly of compounds, nanomaterials, and molecular machines, all based on a selection of leading young scientists par-

ticipating in the 2010 European Young Chemists Award competition. In addition, the authors provide state-of-the-art insights into their respective fields of research and preview future directions.


New Strategies in Chemical Synthesis and Catalysis

Edited by Bruno Pignataro

Molecules at WorkSelfassembly, Nanomaterials, Molecular Machinery Bruno pignataro, Editor

Penned by the most talented young chemists in Europe, this en-gaging work takes readers to the forefront of discovery as it tackles today’s frontier issues in materials science, nanoscience, and chem-istry. Coverage offers accounts of the most recent results of Euro-pean research in areas including the self-assembly of compounds,

nanomaterials, and molecular machines, all based on a selection of leading young scientists participating in the 2010 European Young Chemists Award competition. In addition, the authors provide state-of-the-art insights into their respective fields of research and preview future directions.


Molecules at Work

Edited by Bruno Pignataro

Selfassembly, Nanomaterials, Molecular Machinery






24

Burger’s Medicinal Chemistry, Drug Discovery and DevelopmentEiGHT-VOlUmE SET SEVEnTH EDiTiOn

Donald J. Abraham, David p. Rotella

Now in its seventh edition, Burger’s Medicinal Chemistry, Drug Discovery and Development provides an estab-lished, recognized, authoritative, and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for medicinal chemists and pharmaceu-

tical professions has been thoroughly updated and expanded across eight volumes to incorporate the entire process of drug develop-ment (preclinical testing, clinical trials, etc.) alongside the traditional strengths in medicinal chemistry and drug discovery.


Burger’s Medicinal Chemistry, Drug Discovery and Development

E d i t e d b y D o n a l d J . A b r a h a mD a v i d P. R o t e l l a

SEVENTH EDIT ION

Handbook of MetalloproteinsVOlUmES 4 & 5 TWO-VOlUmE SET

Albrecht messerschmidt

The latest two volumes in this acclaimed series present detailed de-scriptions of the most exciting newly discovered metalloproteins, including those involved in Alzheimer’s disease; those essential in understanding the function of nerves and muscles; and those involved in blood clotting, pho-tosynthesis, and metal ion transport

and storage. Researching the structure and function of metallopro-teins is one of the biggest challenges in modern biological chemistry, and several Nobel Prizes have been awarded to researchers working in this field, including coeditor Robert Huber in 1988.


Risk Management Applications in Pharmaceutical and Biopharmaceutical Manufacturing Hamid mollah, Harold Baseman, mike long

This book explores both the theory and practice of risk management and provides the background, tools, and applications of risk management in pharmaceutical and biologics manu-facturing and operations. It includes many specific examples of use of RM for biological and pharmaceuti-

cal product manufacture. The book also includes useful references and a bibliography for the reader who wishes to gain additional knowledge in the subject. This book helps both industry as well as regulatory agencies to implement compliant and effective risk management approaches and includes case studies to help with understanding.


Risk ManagementApplications in Pharmaceutical

and Biopharmaceutical Manufacturing

Edited by

A. HAMID MOLLAH

MIKE LONG

HAROLD BASEMAN

Supramolecular ChemistryFrom Molecules to Nanomaterials

EiGHT-VOlUmE SET

Jonathan W. Steed, philip A. Gale

Supramolecular Chemistry is the first major reference to link supramolecular chemistry and nanotechnology. Here, a global team of experts presents an overview of the concepts and techniques of modern supramolecular chemistry, demonstrating how these paradigms evolve into nanoscale

systems chemistry, nanotechnology, materials science, and beyond. Breaking down the barriers between synthetic chemistry and ma-terials science, the authors explain the fundamental concepts and provide invaluable practical guidance on the applications and limita-tions of modern instrumental techniques for addressing molecular and materials-based problems. The eight-volume print set is richly illustrated with an average of three images per page and features fully indexed articles and a glossary of key terms.



www.wiley.com/email

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25

Linker Strategies in Solid-Phase Organic Synthesispeter Scott, Editor

Linker Strategies in Solid-Phase Organic Synthesis takes the reader through the evolution of linker units from their genesis in solid-supported peptide chem-istry to the cutting-edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy-to-follow chapters written by experts in their respective

fields that together constitute a comprehensive guide to linker technology while simultaneously serving as a handbook of synthetic transformations that are now possible on solid supports.


Asymmetric Synthesis of Natural ProductsSECOnD EDiTiOn

Ari m. p. Koskinen

Asymmetric Synthesis of Natural Products, Second Edition, introduces readers to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, includ-ing the theory and applications of individual asymmetric reactions. This is followed by chapters on each

of the major individual classes of natural products, their structures, biosynthesis, and interrelationships. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikimic acid derivatives, and alkaloids. For this second edition, the text has been thoroughly updated and expanded and includes new discussions and examples covering atom and redox economies, practical aspects, and environmental awareness. Organocatalysis has also been fully integrated into this new edition.



NanoparticlesFrom Theory to Application

SECOnD EDiTiOn

Günter Schmid, Editor

“Gunter Schmid, the editor of Nanoparticles, is successful in securing the participation of prominent leading experts; he also excels in integrating the chapters in such a way that there is no disjointedness between the differ-ent topics, which is a great advantage for the reader.”—ChemPhysChem

“. . . this book is useful for chemists interested in novel methods of wet-chemical nanoparticle synthesis, [and] also for anyone looking for an introduction into the understanding of the electrical, optical, and magnetic properties of nanoparticles.”—Particle Characterization & Particle Systems


Biocatalysis for Green Chemistry and Chemical Process DevelopmentJunhua (Alex) Tao, Romas Joseph Kazlauskas, Editors

Focusing exclusively on biocatalytic pro-cesses, this book provides a comprehensive overview of green chemistry applications of enzyme-driven transformations for a wide range of industries. The first three introduc-tory chapters overview recent technological advances in enzymes and cell-based trans-formations, and green chemistry metrics

for synthetic efficiency. The remaining chapters are directed to case studies in biotechnological production of pharmaceuticals (small molecules, natural products, and biologics), flavors, fragrance and cosmetics, fine chemicals, value-added chemicals from glucose and biomass, and polymeric materials.


Asymmetric synthesis of natural Products

Ari m.P. Koskinen

second edition

Aromaticity and Other Conjugation EffectsRolf Gleiter, G. Haberhauer

Aromaticity and Other Conjugation Effects focuses on the fundamental concepts of bond theory, delocaliza-tion, aromaticity, and mesomerism, helping readers to understand this challenging part of their chemical education by way of self-study. It pro-vides key knowledge and covers es-sential topics and concepts required of chemistry students of all levels.

Thorough yet stimulating, the book also supplies a framework for understanding properties in view of structure, spectra, and reactivity of many organic molecules.



Rolf Gleiter, Gebhard Haberhauer

Aromaticity and Other Conjugation EffectsWith a Foreword by Roald Hoffmann

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26

Orbital Interactions in ChemistrySECOnD EDiTiOn

Thomas A. Albright, Jeremy K. Burdett, myung-Hwan Whangbo

Orbital Interactions in Chemistry delivers sound coverage of organic, or-ganometallic, inorganic, and solid state chemistry, demonstrating how common orbital situations arise through the whole chemical spectrum. This latest edition features a new chapter on cur-

rent concepts in solid state chemistry, examples of recent advances in the field, more detailed information on trends in the periodic table, expanded information on the mechanics of group theory, and a new chapter on metals.

Hardcover 840 pp 2013 ISBN 978-0-471-08039-8 €149.00 /£113.00/CAD $186.95/USD $169.95

ORBITAL INTERACTIONS IN CHEMISTRY


T. A. Albright J. K. Burdett

M.-H. Whangbo

Chemistry and Analysis of RadionuclidesLaboratory Techniques and MethodologyJukka lehto, xiaolin Hou

Radionuclides are atoms that are un-stable and radioactive, but can used for treating cancers and tumors. Written by chemists for chemists, this is a compre-hensive guide to the important radio-nuclides as well as techniques for their separation and analysis. It introduces nuclear chemists and radiation chem-

ists to the important laboratory techniques and methodologies in the field, providing practical instructions on how to handle nuclear waste and radioactivity in the environment.


Chemistry and Analysis of Radionuclides

Jukka Lehto and Xiaolin Hou

Laboratory Techniques and Methodology

Handbook of Biological Dyes and StainsSynthesis and Industrial ApplicationsR. W. Sabnis

Presenting an up-to-date library on over 200 dyes and stains, this user-friendly handbook is the first to include dyes and stain’s CAS registry number, chemi-cal abstract index name, and melting point. Organized alphabetically by chemical names, Handbook of Biologi-cal Dyes and Stains covers the safety,

toxicity, and adverse effects of dyes and stains on human, animals, and the environment, as well as staining, biological, and industrial applications. With the popular use of dyes and stains, this is a must-have reference book for scientists, professors, and students.


HANDBOOK OF BIOLOGICAL DYES

AND STAINSSY N T H E S I S A N D I N D U ST R I A L A P P L I CAT I O N S

R. W. SABNIS

Fine ChemicalsThe Industry and the Business

SECOnD EDiTiOn

peter pollak

Fine Chemicals is a comprehensive reference for one of the most exciting and challenging segments of the modern chemical industry and a practical guide for developing and succeeding in the multi-billion-dollar fine chemicals business. The book is divided into three parts: The Fine Chemicals Industry, with

definitions, products, technologies, facilities, costs, and management aspects; The Business, covering the market, customers, and market-ing; and Outlook, consisting of changes in the offer/demand scenario, the role of emerging companies in Asia (especially China and India), and a forecast of market changes.


FINE CHEMICALSThe Industry and the Business

SECOND EDITION

Peter Pollak

Supramolecular Soft MatterApplications in Materials and Organic ElectronicsTakashi nakanishi

Supramolecular Soft Matter aptly addresses molecular design and synthesis, as well as the development of smart molecular assem-blies, for organic electronic systems. It identi-fies promising concepts for the successful development of organic/polymeric electron-ics with real-world applications. Unlike other books on the subject, this one is not simply

a compilation of current trends in supramolecular soft matter, but a solid, hands-on guide—written by leading researchers—that will help readers understand and manipulate the electronic properties of supramolecular soft materials for use in organic electronic devices such as photovoltaics and field-effect transistors.


Supramolecular Soft MatterApplications in Materials and Organic Electronics

Edited byTakashi Nakanishi

Design of Heterogeneous CatalystsNew Approaches Based on Synthesis, Characteriza-tion and ModelingUmit S. Ozkan, Editor

This long-awaited reference is the first to focus on the availability of characterization techniques that can examine surface reac-tions at the molecular level. As such, it offers practical examples from a wide array of fields where catalyst design has been based on

new insights and understandings and presents such modern and important topics as self-assembly, nature-inspired catalysis, the nano-scale architecture of surfaces, and theoretical methods. With its inclusion of all the useful and powerful tools for the rational design of catalysts, this is truly a must-have book for every researcher in the field.


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27

Catalysis Without Precious MetalsR. morris Bullock, Editor

Retaining selectivity and improving cost effectiveness—the dream come true of every chemist.

Written for chemists in industry and academia, this ready reference and handbook summarizes recent progress in the field—the development of new catalysts that do not require precious metals. The research presented in this book points the way to how new

catalysts may ultimately supplant the use of precious metals in some types of reactions and highlights the challenges remaining in the development of catalysts that do not require precious metals.


Catalytic Asymmetric Conjugate ReactionsArmando Cordova, Editor

This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conju-gate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid, and base catalysis.

There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules.


Inorganic SynthesesVOlUmE 35

Thomas Rauchfuss, Editor-in-Chief

The Inorganic Syntheses series provides all users of inorganic substances with detailed and foolproof procedures for the preparation of important and timely compounds. It includes complete, up-to-date procedures involving important in-organic substances; and contains subject, contributor, and formula indexes, along with valuable information on transition organometallic compounds, includ-ing species with metal-metal cluster

molecules. This provides an essential working reference for inorganic, organic, organometallic chemists, and materials scientists in industry and academia.


www.wiley-vch.de

Gijsbertus de W

ithStructure, D

eformation, and

Integrity of Materials

1

This fi rst integrated approach to thermomechanics deals equally with the atomic scale, the mesoscale of microstructures and morphology, as well as the macroscopic level of actual components and workpieces for applications. With some 85 examples and 150 problems, it covers the three important material classes of ceramics, polymers, and metals in a didactic manner. The renowned author surveys mechanical material behavior at both the introductory and advanced level, providing read-ing incentive to both students as well as specialists in such disciplines as materials science, chemistry, physics, and mechanical engineering. Backed by fi ve appendices on symbols, abbreviations, data sheets, mate-rials properties, statistics, and a summary of contact mechanics.

Volume I: Fundamentals and ElasticityA. Overview � Constitutive BehaviourB. Basics � Mathematical Preliminaries � Kinematics � Kinetics � Thermodynamics � C, Q and S Mechanics � Structure and BondingC. Elasticity � Continuum Elasticity � Elasticity of Structures � Molecular Basis of Elasticity � Microstructural Aspects of Elasticity

Gijsbertus de With is full professor in materials science and head of the Laboratory of Materials and Interface Chemistry, Eindhoven University of Technology, the Netherlands. He graduated from Utrecht University and received his Ph.D in 1977 from the University of Twente on the structure and charge distribution of molecular crystals. His research inter-ests include the chemical and mechanical processing as well as the thermomechanical behaviour of materials. He is a member of the advisory board of the J. Eur. Ceram. Soc. and the recently founded Coating Science International Confer-ence.

Volume 1 of 2

Edited by R. Morris Bullock

Catalysis Without Precious Metals

www.wiley-vch.de

Gijsbertus de W

ithStructure, D

eformation, and

Integrity of Materials

1

This fi rst integrated approach to thermomechanics deals equally with the atomic scale, the mesoscale of microstructures and morphology, as well as the macroscopic level of actual components and workpieces for applications. With some 85 examples and 150 problems, it covers the three important material classes of ceramics, polymers, and metals in a didactic manner. The renowned author surveys mechanical material behavior at both the introductory and advanced level, providing read-ing incentive to both students as well as specialists in such disciplines as materials science, chemistry, physics, and mechanical engineering. Backed by fi ve appendices on symbols, abbreviations, data sheets, mate-rials properties, statistics, and a summary of contact mechanics.

Volume I: Fundamentals and ElasticityA. Overview � Constitutive BehaviourB. Basics � Mathematical Preliminaries � Kinematics � Kinetics � Thermodynamics � C, Q and S Mechanics � Structure and BondingC. Elasticity � Continuum Elasticity � Elasticity of Structures � Molecular Basis of Elasticity � Microstructural Aspects of Elasticity

Gijsbertus de With is full professor in materials science and head of the Laboratory of Materials and Interface Chemistry, Eindhoven University of Technology, the Netherlands. He graduated from Utrecht University and received his Ph.D in 1977 from the University of Twente on the structure and charge distribution of molecular crystals. His research inter-ests include the chemical and mechanical processing as well as the thermomechanical behaviour of materials. He is a member of the advisory board of the J. Eur. Ceram. Soc. and the recently founded Coating Science International Confer-ence.

Volume 1 of 2

Armando Córdova

Catalytic AsymmetricConjugate Reactions

Volume 35

Thomas B. Rauchfuss,Editor-in-Chief

INORGANICSYNTHESES

CarbohydratesTools for Stereoselective Synthesismike martin Kwabena Boysen, Editor

Comprehensive in scope and closing the gap in current litera-ture, this timely book presents carbohydrate tools as chiral auxiliaries, reagents, complex ligands, and organocatalysts, to-gether with details of their prep-aration, as well as their success-ful application in stereoselective synthesis. Carbohydrates covers the synthesis of carbohydrate

tools and discusses examples of a broad range of different reactions compared to those obtained with the best conventional methods. An indispensable source no organic chemist should be without.


The Power of Functional Resins in Organic SynthesisFernando Albericio, Judit Tulla-puche, Editors

Since work-up procedures in industry are both time- and energy-consuming processes, the interest in solid phases for industrial purposes is very high. For this reason, fast and simple synthesis has become a major focus of research over the last few years. While many books cover solid phase synthesis and combinatorial synthesis, this guide is unique in exclusively

covering the other aspects of solid-phase synthesis. As such, it cov-ers virtually everything you need to know--from supported reagents, to scavengers, resins, and the synthesis of natural products








28

Organic SynthesisStrategy and Controlpaul Wyatt, Stuart Warren

Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart War-ren’s best seller, Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of com-pounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesizing

compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems by either finding an alternative strategy or by controlling any estab-lished strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry, and functional group strategy.



Workbook for Organic SynthesisStrategy and Control


Organic SynthesisThe Disconnection Approach

SECOnD EDiTiOn

Stuart Warren, paul Wyatt

Organic Synthesis: The Disconnection Ap-proach is the long-awaited second edition of a classic textbook, the first to provide a structured course in retrosynthesis—now an important technique used by genera-tions of organic chemists. Now fully revised

and updated with a modern look, it reflects 25 years of advances in organic synthesis, with the addition of new examples and synthetic pathways. Additional material has been added to take the student to the level required by the best-selling sequel, Organic Synthesis: Strategy and Control, and the later chapters have extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.



Workbook for Organic SynthesisThe Disconnection Approach

SECOnD EDiTiOn

This accompanying workbook provides a comprehen-sive graded set of problems to illustrate and develop the themes of each of the chapters in Organic Synthe-sis: The Disconnection Approach, Second Edition.


Fragments of Fullerenes and Carbon NanotubesDesigned Synthesis, Unusual Reactions, and Coordination Chemistrymarina A. petrukhina, lawrence T. Scott, Editors

This book is the first of its kind to reflect upon the intense and rapidly growing interest in open geodesic polyaromatic molecules, specifically focusing on their synthesis and reactivity in metal-binding re-actions. The book broadly covers all aspects related to the fullerene fragment chemistry:

current synthetic techniques, description of the available members of this new family, molecular geometry, and trends in the solid-state packing, as well as extensions into physical properties and new buckybowl-based molecules and materials.


Fragments of Fullerenesand Carbon Nanotubes

Edited by

MARINA A. PETRUKHINALAWRENCE T. SCOTTWith a Foreword by the Nobel Laureate

Professor Harold W. Kroto

How to Write a Successful Science ThesisThe Concise Guide for StudentsWilliam E. Russey, Hans Friedrich Ebel, Claus Bliefert

This handy guide from the best-selling author team of The Art of Scientific Writing shows how you can achieve maximum benefit with relatively little effort. Based on a proven concept that assumes no special talent for writing, the book will be of great

value to both native and nonnative speakers of English. The treat-ment is rich in examples and challenging problems (with solutions provided in an appendix), applicable either in conjunction with a course or for self-study.


The Art of Scientific WritingFrom Student Reports to Professional Publications in Chemistry and Related Fields

SECOnD EDiTiOn

H. F. Ebel, C. Bliefert, W. E. Russey

“A wealth of information contained in a single book of manageable proportions. Students reporting on a simple laboratory experiment and their teachers preparing a paper or lecture will both find this book a constant companion.”

—European Science Editing

“Publish or Perish!” Your introduction and guide to all techniques a good scientific writer needs to master in order to ensure your work gains broad attention. From established researchers to aspiring students, you’ll find this tome to be an invaluable resource to help you improve your technical writing skills. The Art of Scientific Writing emphasizes writing techniques, accurate expression, adherence to accepted standards, and above all, clarity.













29

High Temperature Experiments in Chemistry and Materials ScienceKeith motzfeldt

Now you can conduct dozens of ex-periments that underpin research into materials, including thermodynamics, kinetics, and various physical, chemi-cal; and modelling techniques. This lively how-to includes an introduction to high-temperature research, basic design of high-temperature furnaces, temperature measurement, radiation pyrometry, refractory materials in the

laboratory, vacuum in theory and practice, the design of vacuum furnaces and thermobalances, and more. With highly detailed instrument illustrations and an emphasis on the control and mea-surement of the fundamental properties of temperature, pressure, and mass, this is a highly practical guide that easily translates to academic or industrial labs.


High Temperature Experiments in Chemistry and Materials Science

Ketil Motzfeldt

Anion Coordination ChemistryKristin Bowman-James, Antonio Bianchi, Enrique García-Espana, Editors

Written by the international anion co-ordination experts, this book includes all the recent advances in this emerg-ing interdisciplinary field. Compre-hensive in approach, it covers topics ranging from molecular structures, synthetic strategies, crystallographic, and other analytical aspects to the role in essential biochemical and

biological processes in various applications. An attractive resource for all researchers with an interest in supramolecular chemistry.

Table of Contents: • History of Anion Coordination Chemistry • Anion Coordination Topography • Synthetic Strategies • Template Synthesis • Crystallographic Aspects of Anion Coordination • Theoretical Aspects of Anion-Pi Interactions • Biopolyanion Recognition • Ion Channels • Fluorescent Sensors • Applications.


Anion Coordination Chemistry

Edited by Kristin Bowman-James, Antonio Bianchi, Enrique García-España

Searching for Molecular SolutionsEmpirical Discovery and Its Futureian S. Dunn

Comparing empirical discovery methods for biologically relevant molecules with serendipi-tous discovery and rational design, this compre-hensive book highlights the general approach to empirical discovery, discussing its advantages and disadvantages. In addition to providing a wide-ranging and logical look at experimental

methods for discovery of biologically relevant molecules, the book also includes sections on pragmatic molecular discovery, finding useful natural molecules, empirical methods, directed evolution, high-throughput synthesis and screening, rational molecular design, empirical versus rational design, and the limits of empirical methods.

Hardcover w/Website 458 pp 2010 ISBN 978-0-470-14682-8 €105.00/£80.50/CAD $141.00/USD $128.00

SEARCHING FOR MOLECULAR SOLUTIONS

Empirical Discovery and Its Future

I a n S . D u n n

A Practical Guide to Magnetic Circular Dichroism SpectroscopyW. Roy mason

The book is a technical guide aimed at chem-ists and spectroscopists (graduate students and professionals) that presents a concise de-scription of magnetic circular dichroism (MCD) spectroscopy and how it has advanced the interpretation of molecular electronic spectra. This work in particular calls attention to the added dimension of how experimental MCD

spectra adds important information to that gathered from traditional absorption spectroscopy.


Interested in adopting a Wiley title for a course?

To request an examination copy or if you have any questions please contact your local Wiley

representative.

Don’t know your sales representative?Go to www.wiley.com/college/rep

or in the U.S. call us at 1.800.CALL.WILEY (225.5945) and

choose the desk copy option.

U.S. Call: 800.CALL.WILEY • Canada Call: 800.567.4797 Europe/ROW Call: +44 1243 843294

Attention Instructors!

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www.wiley.com/college/rep


30

Modern Drug SynthesisJie Jack li, Douglas S. Johnson, Editors

Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007) is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of pro-cess synthesis versus the discovery synthetic

route, Modern Drug Synthesis features authoritative coverage by dis-tinguished editors and authors (some chapter authors are the actual inventor of the drug) of 20 different drug molecules.


Modern Drug

Synthesis

E d i t e d b y

J i e J a c k L iD o u g l a s S . J o h n s o n

Greener Fischer-Tropsch Processes for Fuels and Feedstockspeter m. maitlis, Arno de Klerk

Add this comprehensive and up-to-date over-view of these titular processes, with coverage ranging from the basic science to commercial issues, to your shelf. In addition to the chemi-cal and industrial side of Fischer-Tropsch syn-thesis, this monograph deals with process economics as well as such green concepts as

sustainability and environmental care. The result is a practical refer-ence for researchers and engineers working on fuel processing or fuel cell technologies in industry, as well as a great introductory book for graduate courses in chemistry and chemical engineering.


Greener Fischer-Tropsch Processes

Edited by Peter M. Maitlis, Arno de Klerk

for Fuels and Feedstocks

Surfactants from Renewable Resourcesmikael Kjellin, ingegärd Johansson, Editors

Most surfactants today are readily biodegrad-able and low-toxic to the aquatic environ-ment—the two criteria for green surfactants. However, there is still interest in finding more renewable sources for surfactants and there are ways of making the building blocks for these surfactants from natural sources. This text focuses on bio-based products that

have the potential to improve sustainability of natural resources and environmental quality, while competing on an economic level, and brings together, in one source, information on new biodegradable surfactants with safer properties for modern industrial formulations.


Supported Ionic LiquidsRasmus Fehrmann, Anders Riisager, marco Haumann, Editors

First of its kind within a very hot field of topic, Supported Ionic Liquids introduces SILP materials and the fundamentals. This debut book dis-cusses ionic liquids, porous supports, syntheses, and characterization, and features an important case study sec-tion highlighting applications within the catalytic production of:

• Bulk chemicals

• Fine chemicals

• Environmental processes

• Biotechnology

• Energy production

• And gas separation.

In addition, each case study features the most significant authors available describing the underlying research. A final section of con-cluding remarks addresses the perspectives and outlook.


Supported Ionic Liquids

Edited by Rasmus Fehrmann, Anders Riisager and Marco Haumann

Fundamentals and Applications

The Bioinorganic Chemistry of ChromiumJohn Vincent

Take a critical look at what the biochemical data indicate about chromium’s role in the body and the biological mechanisms of its toxicol-ogy. Topics covered include:

• What do we know about the bio-chemical roles and mechanisms of chromium?

• Is chromium an essential element in the mammalian diet?

• Is chromium(III) effective as a nutraceutical, a therapeutic agent, and as a supplement in animal feed?

• What is the biochemistry behind the toxicology of chromium(III) and chromium(VI): the mechanisms of metabolism, genetic and epigenetic effects, and disruption of cell signalling?

• What are the current chromium(VI) policies and positions from regulatory agencies?


The

BioinorganicchemisTry of

John B. Vincent

chromium

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Aldrich® Chemistry and John Wiley & Sons are pleased to announce the winner of the EROS Best Reagent Award 2012

About the EROS Best Reagent AwardSponsored by Aldrich® Chemistry and John Wiley & Sons, the EROS Best Reagent Award was created to honour the work of the authors to the online edition of Encyclopedia of Reagents for Organic Synthesis [EROS and e-EROS] which launched in April 2001. Updated every year with around 200 new or updated articles, these contributions from carefully selected synthetic chemists ensure that this collection of reagents and catalysts remains a primary source of information for chemists at the bench.

Award Committee:

David Crich, Philip Fuchs, André Charette, Tomislav Rovis, Leo Paquette, Gary Molander, Peter Wipf

For more information about EROS and the EROS Best Reagent Award visit wileyonlinelibrary.com/ref/eros

Bruce H. Lipshutz University of California, Santa Barbara, California, USA

For the reagent [(R)-(–)-DTBM-SEGPHOS]CuH • [(S)-(+)-DTBM-SEGPHOS]CuH Aldrich Catalog: 762458/762938 • CAS: 566940-03-2/210169-40-7

The reagent is a catalyst which can be used in homogeneous or heterogeneous form and it has been applied to a number of copper-catalyzed asymmetric reductions, hydrosilylations, and reductive aldol reactions. The article on the Award winning reagent by Bruce H. Lipshutz and co-workers Danielle M. Nihan and Benjamin R. Taft was published in EROS in March 2009.

These reagents are available to purchase through Aldrich.com.

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Instant Access to Over 200,000 Reactions

Scott E. Denmark, Editor-in-Chief ISBN 978-0-471-26418-7

Organic Reactions is a comprehensive collection of important synthetic reactions, together with a critical discussion

of the reaction, and tables that organize all published examples of the reactions. The publication process entails a

comprehensive peer-review process, ensuring the high quality and attention to detail for which this series is noted.

Every volume published since 1942 is available online and fully integrated into the Wiley Online Library. You can

search the full text, as well as browse, to find reactions you want alongside all the supporting information you need

to inform your own experimental work.

For more information, visit wileyonlinelibrary.com/db/or or call 800.245.6217.

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