chemistry 11.2-glycolysis-–-part-2

15
Chapter 11 (part 2) Regulation of Glycolysis

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Page 1: Chemistry 11.2-Glycolysis-–-part-2

Chapter 11 (part 2)

Regulation of Glycolysis

Page 2: Chemistry 11.2-Glycolysis-–-part-2
Page 3: Chemistry 11.2-Glycolysis-–-part-2

Lactate formation

  

H3C C C

OO

O

NADH NAD

NADH NAD

H3C CH

C

OHO

O

Page 4: Chemistry 11.2-Glycolysis-–-part-2

Cori Cycle

Page 5: Chemistry 11.2-Glycolysis-–-part-2

Alcohol Fermentation

Page 6: Chemistry 11.2-Glycolysis-–-part-2

Free Energy Change in Glycolysis

HexokinasePhosphofructokinase-1

Pyruvate kinase

Page 7: Chemistry 11.2-Glycolysis-–-part-2

Control Points in Glycolysis

Page 8: Chemistry 11.2-Glycolysis-–-part-2

Insulin Induced Exocytosis of Glucose Transporter

Page 9: Chemistry 11.2-Glycolysis-–-part-2

Effect of ATP on PFK-1 Activity

Page 10: Chemistry 11.2-Glycolysis-–-part-2

Effect of ADP and AMP on PFK-1 Activity

Page 11: Chemistry 11.2-Glycolysis-–-part-2

Regulation of PFK by Fructose-2,6-bisphosphate

Page 12: Chemistry 11.2-Glycolysis-–-part-2

Glucagon Regulation of PFK-1 in Liver

Page 13: Chemistry 11.2-Glycolysis-–-part-2

Pyruvate Kinase Regulation

Page 14: Chemistry 11.2-Glycolysis-–-part-2

Other Sugars can

enter glycolysis

Page 15: Chemistry 11.2-Glycolysis-–-part-2