cheminform abstract: the structure of a new cardenolide diglycoside and the biological activities of...

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ChemInform 2011, 42, issue 01 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Steroids U 0300 DOI: 10.1002/chin.201135184 The Structure of a New Cardenolide Diglycoside and the Biological Activities of Eleven Cardenolide Diglycosides from Nerium oleander. — Compound (I) is iso- lated as new cardenolide diglycoside from Nerium oleander together with ten known structurally related diglycosides. Their in vitro anti-inflammatory potency, cytotoxicity and multidrug resistance-reversal activity are evaluated. (I) shows moderate effects on calcein accumulation. — (ZHAO*, M.; et al.; Chem. Pharm. Bull. 59 (2011) 3, 371-377 ; Coll. Chem. Chem. Eng., Qiqihar Univ., Qiqihar 161006, Heilongjian, Peop. Rep. China; Eng.) — H. Haber 35- 184

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Page 1: ChemInform Abstract: The Structure of a New Cardenolide Diglycoside and the Biological Activities of Eleven Cardenolide Diglycosides from Nerium oleander

SteroidsU 0300 DOI: 10.1002/chin.201135184

The Structure of a New Cardenolide Diglycoside and the Biological Activities of Eleven Cardenolide Diglycosides from Nerium oleander. — Compound (I) is iso-lated as new cardenolide diglycoside from Nerium oleander together with ten known structurally related diglycosides. Their in vitro anti-inflammatory potency, cytotoxicity and multidrug resistance-reversal activity are evaluated. (I) shows moderate effects on calcein accumulation. — (ZHAO*, M.; et al.; Chem. Pharm. Bull. 59 (2011) 3, 371-377 ; Coll. Chem. Chem. Eng., Qiqihar Univ., Qiqihar 161006, Heilongjian, Peop. Rep. China; Eng.) — H. Haber

35- 184

ChemInform 2011, 42, issue 01 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim