cheminform abstract: ring-closing metathesis of sulfoximine-substituted n-tethered trienes: modular...
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Multi-membered N-heterocyclesR 0690 DOI: 10.1002/chin.201140168
Ring-Closing Metathesis of Sulfoximine-Substituted N-Tethered Trienes: Modu-lar Asymmetric Synthesis of Medium-Ring Nitrogen Heterocycles. — Sulfox-imine-substituted N-tethered trienes, synthesized from the corresponding homoallylic amines, undergo ruthenium-catalyzed ring-closing reaction to give the desired hetero-cycles with high diastereoselectivity. In contrast, ring closure for diene (VII) is only observed adding Ti(O-iPr)4 as co-catalyst. — (MAHAJAN, V.; GAIS*, H.-J.; Chem. Eur. J. 17 (2011) 22, 6187-6195, http://dx.doi.org/10.1002/chem.201003172 ; Inst. Org. Chem., RWTH Aachen, D-52074 Aachen, Germany; Eng.) — S. Adam
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ChemInform 2011, 42, issue 40 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim