2002 fused pyridine derivatives

fused pyridine derivativesR 0450

29 - 163Reactions of Pyridine Analogues of Aza-o-xylylenes Generated from1,3-Dihydroisothiazolo[4,3-b]pyridine 2,2-Dioxides (Pyridosultams)– Formation of 2:1 Adducts with N-Phenylmaleimide. — Pyrido-sultams generated from 3-amino-2-chloropyridines and alkanesulfonyl chloridesreact with maleimide in a Diels–Alder reaction to give tetrahydronaphthyridinesand further 2:1 adducts. Intramolecular Diels–Alder reaction results in forma-tion of tricyclic (VII) which can be converted to the diazasteroid framework(XI). — (WOJCIECHOWSKI, KRZYSZTOF; KOSINSKI, SZYMON; Eur. J.Org. Chem. (2002) 5, 947-954; Inst. Org. Chem., Pol. Acad. Sci., PL-01-224Warsaw, Pol.; EN)

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