cheminform abstract: first efficient preparation of enantiopure 10-bromofenchone: the key...
TRANSCRIPT
2002 terpenes
terpenesU 0200
02 - 197First Efficient Preparation of Enantiopure 10-Bromofenchone: TheKey Intermediate to C10-Substituted Fenchone-Derived ChiralSources. — Commercially available (1R)-fenchone (I) is converted inthree steps with 78% overall yield into enantiopure 10-bromofenchone (VI).The synthesis involves two consecutive Wagner–Meerwein rearrangementsof the fenchone skeleton. — (GARCIA MARTINEZ, ANTONIO; TESOVILAR, ENRIQUE; GARCIA FRAILE, AMELIA; DE LA MOYA CERERO,SANTIAGO; LORA MAROTO, BEATRIZ; Tetrahedron Lett. 42 (2001) 37,6539-6541; Dep. Quim. Org., Fac. Cienc. Quim., Univ. Complutense, E-28040Madrid, Spain; EN)
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