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2000 other bioactive products other bioactive products U 1300 07 - 225 F-11334s, New Inhibitors of Membrane-Bound Neutral Sphingomyeli- nase. — Five natural products (I), (II), (III) are isolated from Acremonium murorum and found to have inhibitory activity towards magnesium-dependent sphingomyelinase. Derivatives (I) show the best activity due to free hydroxyl groups in the hydroquinone moiety. — (TANAKA, MASAHIRO; NARA, FUTOSHI; YAMASATO, YOKO; ONO, YASUNORI; OGITA, TAKESHI; J. Antibiot. 52 (1999) 9, 827-830; Biosci. Res. Lab., Sankyo Co., Ltd., Shinagawa, Tokyo 140, Japan; EN) 1

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Page 1: ChemInform Abstract: F-11334s, New Inhibitors of Membrane-Bound Neutral Sphingomyelinase

2000 other bioactive products

other bioactive productsU 1300

07 - 225F-11334s, New Inhibitors of Membrane-Bound Neutral Sphingomyeli-nase. — Five natural products (I), (II), (III) are isolated from Acremoniummurorum and found to have inhibitory activity towards magnesium-dependentsphingomyelinase. Derivatives (I) show the best activity due to free hydroxylgroups in the hydroquinone moiety. — (TANAKA, MASAHIRO; NARA,FUTOSHI; YAMASATO, YOKO; ONO, YASUNORI; OGITA, TAKESHI; J.Antibiot. 52 (1999) 9, 827-830; Biosci. Res. Lab., Sankyo Co., Ltd., Shinagawa,Tokyo 140, Japan; EN)

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