cheminform abstract: dynamic combinatorial libraries: new opportunities in systems chemistry

1

ChemInform 2011, 42, issue 17 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Organic chemistry Z 0200 DOI: 10.1002/chin.201117219 Dynamic Combinatorial Libraries: New Opportunities in Systems Chemistry — [110 refs.]. — (HUNT, R. A. R.; OTTO*, S.; Chem. Commun. (Cambridge) 47 (2011) 3, 847-858, http://dx.doi.org/10.1039/c0cc03759a ; Stratingh Inst. Chem., Univ. Groningen, NL-9747 AG Groningen, Neth.; Eng.) — R. Langenstrassen 17- 219

Upload: rosemary-a-r-hunt

Post on 11-Jun-2016

213 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

TRANSCRIPT

Page 1: ChemInform Abstract: Dynamic Combinatorial Libraries: New Opportunities in Systems Chemistry

Organic chemistryZ 0200 DOI: 10.1002/chin.201117219

Dynamic Combinatorial Libraries: New Opportunities in Systems Chemistry — [110 refs.]. — (HUNT, R. A. R.; OTTO*, S.; Chem. Commun. (Cambridge) 47 (2011) 3, 847-858, http://dx.doi.org/10.1039/c0cc03759a ; Stratingh Inst. Chem., Univ. Groningen, NL-9747 AG Groningen, Neth.; Eng.) — R. Langenstrassen

17- 219

ChemInform 2011, 42, issue 17 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

High Throughput Screening of Combinatorial Libraries for

Phenotype-information-phenotype cycle for deconvolution of ... · Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex

Combinatorial Preconditioners for Finite Element …primage.tau.ac.il/libraries/theses/exeng/free/2188664.pdfcombinatorial preconditioning of nite-element matrices. In particular,

Encoded Combinatorial Libraries - · PDF fileCombinatorial Chemistry Combinatorial chemistry is the systematic and repetitive covalent assembly of reactant molecules to create a diverse

Combinatorial Chemistry. Synthesis of many structures (diversity) combinatorial technology, combinatorial library molecular diversity What is Combinatorial

Combinatorial Security Testing: Combinatorial Testing Meets

Al-Mustansiriya University · DETECTION, PURIFICATION, AND ANALYSIS: Detection, analysis, and purification of combinatorial libraries places high demands on existing analytical techniques

Combinatorial Peptide and Nonpeptide Libraries...Immobilization and Derivatization of Dicarboxylic Acids and Their Derivatives 44 Ring Closure Reactions 46 Heterocyclic Compounds:

Combinatorial Libraries of Synthetic Peptides as a Model ... › Papers › 2010publication_peptidelibraries.pdfAnal. Chem. 2010, 82, 6559–6568 10.1021/ac100910a 2010 American Chemical

Used extensively in relation with drug discovery Principle of Combinatorial Chemistry ◦ Generation of Compound Libraries from Molecular Building blocks

ChemInform RxnFinder

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding

Protein exPression & AnAlysis Application note · 2017. 9. 14. · tein synthesis for functional screening of large combinatorial libraries. Firstly, iVtt offers substantial time

D9 Drug design Compound libraries Combinatorial and parallel chemistry The use of computers Modifications for polarity Chiral synthesis

Review - PNASScheme of how peptide combinatorial libraries can be constructed using the light-directed, spatially addressable parallel chemical synthetic approachdevelopedbyFoder et

HPLC Combinatorial Libraries

PSEUDO-DYNAMIC COMBINATORIAL LIBRARIES: A …digitool.library.mcgill.ca/thesisfile85059.pdf · PSEUDO-DYNAMIC COMBINATORIAL LIBRARIES: A RECEPTOR-ASSISTED COMBINATORIAL CHEMISTRY

Combinatorial Libraries of Synthetic Peptides as a Model ...€¦ · Combinatorial Libraries of Synthetic Peptides as a Model for Shotgun Proteomics Brian C. Bohrer, †Yong Fuga

NMR-based screening of combinatorial libraries to target

Combinatorial Generation - 1stWorks1stworks.com/ref/RuskeyCombGen.pdf · Combinatorial Generation Combinatorial Generation Combinatorial Generatio ombinatorial Generation Combinatorial

Encoded Combinatorial Libraries - Department of Chemistry€¦ · Asp GG AA CCG GCA GAGA Lys AAGG CGA CGA GACG Phe CGGC GCA ACG CAGG Ala GCCG TGC GTG CG AA ... For combinatorial chemistry

The Path to Platinum: The Evolution of Human Combinatorial Antibody Libraries (HuCAL€¦ · · 2017-03-25The Evolution of Human Combinatorial Antibody Libraries ... S G V T T K

One-bead-one-structure combinatorial libraries · One-Bead-One-Structure Cornbinatorial Libraries Kit S. Lam Arizona Cancer Center and Department of Medicine University of Arizona

Fluorous Synthesis and Separation - Sigma-Aldrich · combinatorial libraries by solution-phase parallel synthesis. ... Modern Solvents in Organic Synthesis; P. Knochel, ... Products

Combinatorial Libraries of Synthetic Peptides as a Model for ......Combinatorial Libraries of Synthetic Peptides as a Model for Shotgun Proteomics Brian C. Bohrer, †Yong Fuga Li,‡

COMBINATORIAL CHEMISTRY AND DYNAMIC COMBINATORIAL CHEMISTRY

Fast Descriptor Calculation for Combinatorial Libraries Geoff Downs & John Barnard Sheffield, UK

Liquid-phase combinatorial synthesis › content › pnas › 92 › 14 › 6419.full.pdf · combinatorial libraries. In essence what we have done is apply "liquid-phase" synthesis

Open Access CSgator:kanjintegratedkwebkplatformk forjcompoundksetkanalysis · 2019. 3. 4. · Parkjet al. J Cheminform Pagek6kofk8 currentlackofenoughcompound-targetdataevenafter

CELL-TARGETED RIBOSOME-INACTIVATING PROTEINS DERIVED … · CELL-TARGETED RIBOSOME-INACTIVATING PROTEINS DERIVED FROM PROTEIN COMBINATORIAL LIBRARIES ... 1.4.3 Ribosome Display and

The importance of understanding ligand-binding sites in ... · Validated Targets Combinatorial Chemistry Libraries + = Ligand-Receptor Complexes THE “DOCKING ” PROBLEM Computed

Comprehensive Solutions for Purification and Analysis of Combinatorial Libraries

Synthesis and Metrology of Combinatorial Materials Libraries€¦ · in discussion with combinatorial materials science ... analysis Integration with theory, databases, standards,

Combinatorial libraries: strategies and methods for …...Discovery chemistry: stage 1 • High Throughput Screening (HTS): – Rapid, automated screening of compounds for specific

Combinatorial Peptide and Nonpeptide Libraries