2001 biochemical syntheses, microbiological syntheses

biochemical syntheses, microbiological synthesesO 0035

07 - 035Asymmetric Reduction of Ketones by Geotrichum candidum in thePresence of Amberlite XAD, a Solid Organic Solvent. — In theAmberlite XAD-7/H2O biphasic system, simple aliphatic and aromatic ketonesare reduced by G. candidum to the corresponding (S)-alcohols in excellentenantiomeric excesses. The stereoselectivity of the microbial reduction iseffectively controlled by the hydrophobic polymer, whereas in its absence onlylow enantioselectivities are observed. — (NAKAMURA, KAORU; FUJII,MIKIO; IDA, YOSHITERU; Perkin 1 (2000) 19, 3205-3211; Inst. Chem. Res.,Kyoto Univ., Uji, Kyoto 611, Japan; EN)

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