characterization of ultrasound elevation beamwidth artefacts for brachytherapy needle insertion...
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Characterization of Ultrasound Characterization of Ultrasound Elevation Beamwidth Artefacts for Elevation Beamwidth Artefacts for
Brachytherapy Needle InsertionBrachytherapy Needle Insertion
Mohammad Peikari
Advisor :Dr. Gabor Fichtinger
Laboratory for Percutaneous SurgerySchool of Computing, Queen’s University, Canada
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Motivation
•All US-guided procedure suffers from section thickness artifacts•Appearance of anatomy and localization of surgical tools affected
•Motivating application is the transrectal ultrasound (TRUS) guided prostate brachytherapy
Gall BladderGall Bladder((arrow points to false artifactarrow points to false artifact))
Figure: http://www.gehealthcare.com/caen
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Achievements
•Nominated for best master research award – IEEE Kingston section 2011
•Journal of Medical Physics 2012 (ISI impact factor = 3.25)•Medical Image Computing and Computer Assisted
Intervention (MICCAI) conference 2011 (peer reviewed conference proceedings)
•International Society for Optics and Photonics (SPIE) 2011 (nominated for best student paper award)
•Patented a variation of the presented device by other members of the group
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Prostate Cancer•Second leading cause of cancer related death •Treatment options:
•Prostatectomy•external beam radiation•Brachytherapy
•Potential advantages of brachytherapy:•Outpatient treatment•Comparable to the other treatment options•Ability to target tumor and avoid healthy tissues
•Potential disadvantages of brachytherapy:•Side effects may vary•Highest quality is hard to achieve
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Prostate Brachytherapy
•Permanent implantation of radioactive seeds under live ultrasound (US) guidance
Figure credited to C. Chao from Perk lab
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Ultrasound
www.en.wikibooks.org and http://www.frca.co.uk
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Treatment Planning
Margin: 3-6 mm
100%100%isodoseisodose
www.oncoprof.net
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Ultrasound Guided Needle Insertion
1-Postate with target implant
location
2-Needle insertion 3-Needle reaches the target
http://www.eecs.berkeley.edu
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Treatment Validation and Plan Update
E. Dehghan et al. “Prostate Implant Reconstruction from C-arm Images with Motion-Compensated Tomosynthesis”,Medical Physics, Vol. 38(10), pp. 5290 – 5302, 2011.
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Procedure
http://www.prostatebrachytherapyinfo.net/PCT21.html
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Section Thickness Artifacts in TRUS
a) Main beam thickness b) Side lobe energies
Side lobe
Main lobe
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Objectives
•Characterization the ultrasound elevation beamwidth
•Generate US beam profile•Compare main beam thickness and side lobe
artifacts•Measure needle tip localization offsets •Recommendations to reduce the effects of these
artifacts
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•Goldstein (Ultrasound, 1981)
•Skolnick (Radiology, 1991)–Compared scan plane and section-thicknesses–Used an inclined surface and a phantom with
multiple filaments 1cm apart in a vertical row–Difference compared to proposed method:
Needs segmentation of the filaments•Richard (Radiology, 1999 )
–Used several inclined surfaces located successively below each other in a phantom
–Difference compared to proposed method :more complex phantom, results only at specific
positions
Prior Work on Beamwidth Artifacts
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Prior Work on Side Lobe Artifacts
•Laing (Radiology, 1982)
–Illustrated the genesis of side lobe artifacts–Employed round plastic container filled with
de-gassed water and a sponge –Compared the effects of main and side lobe
artifacts
•Barthez (Radiology and Ultrasound, 1997)
–Reproduced the artifacts using metallic wires and wooden tongue depressor
–Employed all sorts of US transducer–Shape and intensity varied with US
transducer type
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Beamwidth Measurement
•CD≈Ultrasound beamwith•The US beamwidth is larger when side lobe energies present
around the main lobe
Beamwidth
45⁰ 45⁰
Main beam thickness Main and side lobe beams thickness