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    How Cells Reproduce

    Chapter 8

    Part 2

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    8.6 Sexual Reproduction and Meiosis

    Two modes of reproduction: asexual and sexual

    Asexual reproduction Reproductive mode by which offspring arise from

    one parent and inherit that parents genes only

    Offspring of asexual reproduction are clones

    Clone

    A genetically identical copy of an organism

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    Sexual Reproduction

    Offspring of sexual reproduction vary in shared

    traits

    Sexual reproduction

    Reproductive mode by which offspring arise from

    two parents and inherit genes from both

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    Inheriting Chromosome Pairs

    Offspring of most sexual reproducers inherit

    pairs of chromosomes, one of each pair from the

    mother and the other from the father

    Except for a pair of nonidentical sex

    chromosomes, the members of a chromosome

    pair have the same length, shape, and set ofgenes these are homologous chromosomes

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    Chromosome Pairs

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    Variation in Traits

    Sexual reproduction mixes up alleles from two

    parents, resulting in new combinations of alleles(and traits) in offspring

    Variations in allele combinations are introduced

    during meiosis

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    Meiosis Halves the Chromosome Number

    Meiosis occurs in immature reproductive cells(germ cells) of sexually reproducing eukaryotes,forming male and female haploid gametes

    Gamete

    Mature, haploid reproductive cell

    Haploid (n)

    Having one of each type of chromosomecharacteristic of the species

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    Meiosis Halves the Chromosome Number

    Meiosis sorts the chromosomes into new nuclei

    twice (meiosis I and meiosis II)

    Duplicated chromosomes of a diploid nucleus

    (2n) are distributed into four haploid nuclei (n)

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    Meiosis I and Meiosis II

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    each chromosome in the cell pairswith its homologous partner

    then the partners separate

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    Gamete Formation

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    Reproductive organsof a human male

    testis(where sperm

    originate)

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    Reproductive organsof a human female

    ovary(where eggs

    develop)

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    Animation: Reproductive organs

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/gamete_producing.html
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    Animation: Sperm formation

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/sperm_formation.html
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    Animation: Egg formation

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/egg_formation.html
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    8.7 Meiosis

    In meiosis, two nuclear divisions halve the

    parental chromosome number

    Meiosis I Meiosis II

    Meiosis shuffles parental combinations of

    alleles, introducing variation in offspring

    Crossing over in prophase I

    Random assortment in metaphase I

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    Crossing Over

    Crossing over is recombination between

    nonsister chromatids of homologous

    chromosomes which produces new

    combinations of parental alleles

    Crossing over

    Homologous chromosomes exchangecorresponding segments during prophase I of

    meiosis

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    Fig. 8-11b, p. 148

    crossover

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    Animation: Crossing over

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/crossover.html
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    Fig. 8-10b, p. 147

    5 Prophase II 6 Metaphase II 7 Anaphase II 8 Telophase II

    There is no DNAreplication between thetwo nuclear divisions.

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    Fig. 8-10b, p. 147Stepped Art

    one pair of homologouschromosomes

    plasmamembrane

    spindlemicrotubules

    nuclear envelopebreaking up

    centrosome

    There is no DNAreplication between

    the two nucleardivisions.

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    Animation: Crossover review

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/crossover_review.html
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    Animation: Meiosis I and II

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/meiosis_I_and_II.html
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    Gamete Formation in Animals

    Germ cells in the reproductive organs of animals

    give rise to sperm or eggs

    Sperm

    Mature male gamete

    Egg

    Mature female gamete, or ovum

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    8.9 When Control is Lost

    The cell cycle has built-in checkpoints that allow

    problems to be corrected before the cycle

    advances

    Checkpoint gene products are gene expression

    controls that advance, delay, or block the cell

    cycle in response to internal and externalconditions

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    Checkpoint Genes

    BRCA genes are tumor suppressor geneswhose products normally repair broken DNA

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    8.10 Impacts/IssuesRevisited

    The HeLa cell line was established more than 50

    years ago without Henrietta Lacks knowledge or

    consent

    Today, consent forms are required to take tissue

    samples, and it is illegal to sell ones own organsor tissues

    Digging Into Data:

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    HeLa Cells Are a Genetic Mess

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    Video: ABC News: Genetically modified

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    cancer fighters

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/Cancer_Fighters.html
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    Video: ABC News: Blood test for lung

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    cancer

    http://localhost/var/www/apps/conversion/tmp/scratch_5/videos_animations/Lung_Cancer.html
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