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Page 1: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:
Page 2: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Chapter 9 Sexual Reproduction and Meiosis

Ultrasound: © Chad Ehlers/Glow Images

Copyright © McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of McGraw-Hill Education.

Page 3: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

What are the 2 forms of reproduction?

Section 9.1 Figure 9.1

1) Asexual2) Sexual

Human family: © Corbis RF; Amoeba reproducing by binary fission: © Carolina Biological Supply

Company/Phototake; Mother cat and kittens: © Jane Burton/Dorling Kindersley/Getty Images

Page 4: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Why Sex?

Section 9.1 Figure 9.2

• Genetic diversity • Increases chance to survive

Page 5: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Semen attack unsuspecting ovum

Page 6: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.11

Pair of homologouschromosomes

Locus

Centromere

Sisterchromatids

One duplicatedchromosome

Homologous chromosomes

Page 7: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Diploid Cells Contain Two Homologous Sets of Chromosomes

Section 9.2 Figure 9.3

Most cells in a sexually reproducing organism have two sets of chromosomes: one from the father and one from the mother.

All karyotype photos: © CNRI/Science Source

Page 8: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Diploid Cells Contain Two Homologous Sets of Chromosomes

Section 9.2 Figure 9.4

Homologous pair:• look alike chromosomes• carry the same sequence of

genes for the same traits • ALLELES different versions

Page 9: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

The photo below shows two chromosomes from one cell. Which statement is true?

A. Both came from theperson’s mother.B. The 1-2 pair is identicalto the 3-4 pair.C. 1 is identical to 2.D. The chromosomes havenot been replicated yet.

1 2 3 4

Flower: © Doug Sherman/Geofile/RF

Page 10: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.12AHaploid gametes (n 23)

Egg cell

Sperm cell

Fertilization

n

n

Meiosis

Ovary Testis

Diploidzygote

(2n 46)2n

MitosisKey

Haploid stage (n)

Diploid stage (2n)Multicellular diploid

adults (2n 46)

Page 12: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Overview

Section 9.3 Figure 9.6Human female karyotype: © James Cavallini/Science Source

Meiosis• scrambles alleles• halves the chromosome number

2n=4 n=2

n=2

MEIOSIS I MEIOSIS II

Page 13: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.12B

A pair ofhomologouschromosomesin a diploidparent cell

A pair ofduplicatedhomologouschromosomes

Sisterchromatids

1 2 3

INTERPHASE MEIOSIS I MEIOSIS II

Page 14: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

In Meiosis, DNA Replicates Once, but the Nucleus Divides Twice

Section 9.4 Figure 9.7

2n=4

All photos © Ed Reschke

Page 15: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

In Meiosis, DNA Replicates Once, but the Nucleus Divides Twice

Section 9.4 Figure 9.7

n=2

All photos © Ed Reschke

Page 16: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.13_3

Cleavagefurrow

Telophase I and Cytokinesis

Page 17: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.13_4

Prophase II Metaphase II Anaphase II

MEIOSIS II: Sister chromatids separate

Sister chromatidsseparate

Haploid daughter

cells forming

Telophase IIand Cytokinesis

Page 18: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Interphase

Page 19: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Prophase I

• Synapsis

• Tetrad formation

• Crossing over

Meiosis I

Page 20: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Generates Variability

Section 9.5 Figure 9.8

During crossing over, two homologous chromosomes exchange genetic material during prophase I.

Meiosis I

Page 21: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.16

Coat-colorgenes

Eye-colorgenes

Brown Black

Meiosis

White Pink

Tetrad in parent cell

(homologous pair of

duplicated chromosomes)

Chromosomes of

the four gametes White coat (c);pink eyes (e)

Brown coat (C);black eyes (E)

EC

ec

e

E

E

ec

c

C

C

Crossing OverWhat are the results for the chromosomes after crossing over?

Meiosis I

Page 22: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.17B_2

Separation of homologous

chromosomes at anaphase I3

C E

C e

Chiasma

c

c

E

e

C E

c e

Crossing OverMeiosis I

Page 23: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.17B_3

Separation of chromatids atanaphase II andcompletion of meiosis

Parental type of chromosome

Recombinant chromosome

Recombinant chromosome

Parental type of chromosome

Gametes of four genetic types

C E

eC

4

Ec

c e

EC

eC

c E

c e

Crossing OverMeiosis I

Page 24: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Metaphase I

• Metaphase plate

• Independent assortment

• 2n 223 => 8 million

Meiosis I

Page 25: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Generates Variability

Section 9.5 Figure 9.9

In independent assortment, chromosome pairs align randomly during metaphase I.

Meiosis I

Page 26: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.15_s1

Possibility A

Two equally probablearrangements ofchromosomes at

metaphase I

Possibility B

Independent AssortmentMeiosis I

Page 27: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.15_s2

Possibility A

Two equally probablearrangements ofchromosomes at

metaphase I

Possibility B

Metaphase II

Independent AssortmentMeiosis I

Page 28: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.15_s3

Possibility A

Two equally probablearrangements ofchromosomes at

metaphase I

Possibility B

Metaphase II

Gametes

Combination 3 Combination 4Combination 2Combination 1

Independent AssortmentMeiosis I

Page 29: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Anaphase I

• Homologous chromosomes separate

• Sister chromatids attached

Meiosis I

Page 30: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Telophase I & Cytokinesis

• Cleavage furrow

• Cell Plate

• 2 cells

• Haploid

• Sister chromatids attached

Meiosis I

Page 31: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Half Time!

• Rest break

• Reformation of nucleus, nucleolus, etc.

• NO MORE DNA Replication!!!

• Temporary, if it occurs at all

Page 32: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Prophase II

• Same as prophase of mitosis

Meiosis II

Page 33: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Metaphase II

• Metaphase plate

• Line up single file

Meiosis II

Page 34: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Anaphase II

• Sister chromatids separate

Meiosis II

Page 35: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Telophase II & Cytokinesis

• 4 cells

• haploid

• variation

Meiosis II

Page 36: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.14

Prophase

Metaphase

Duplicated

chromosome(two sister

chromatids)

MITOSIS

Parent cell

(before chromosome duplication)

Chromosomeduplication

Chromosomeduplication

Site of

crossing

over

2n 4

Chromosomes

align at the

metaphase plate

Tetrads (homologous

pairs) align at the

metaphase plate

Tetrad formed

by synapsis of

homologous

chromosomes

Metaphase I

Prophase I

MEIOSIS I

Anaphase

Telophase

Sister chromatids

separate duringanaphase

2n 2n

Daughter cells of mitosis

No further

chromosomalduplication;

sister

chromatidsseparate during

anaphase II

n n n n

Daughter cells of meiosis II

Daughter

cells ofmeiosis I

Haploid

n 2

Anaphase I

Telophase I

Homologous

chromosomesseparate during

anaphase I;

sister

chromatids

remain together

MEIOSIS II

Page 37: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Produces Human Gametes

Section 9.8 Figure 9.15

Sperm cells form in the testes. Egg cells form in the ovaries.

Sperm contacting egg: © Francis Leroy, Biocosmos/Science Source

Page 38: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Produces Human Gametes

Section 9.8 Figure 9.16

Page 39: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Produces Human Gametes

Section 9.8 Figure 9.17

Page 40: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Spermatogenesis

• Spermatogenesis

• Puberty

• 4 potential sperm

• Acrosome cap

Page 41: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Mature Sperm

Page 42: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Oogenesis

• Oogenesis

• Prior to birth (7 month)• Arrested: Prophase I

• Puberty• Arrested: Metaphase II

• Fertilization• Completion of meiosis

• Polar bodies

Page 43: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Ovum development

Page 44: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Generates Variability

Section 9.5

• Identical twins: embryo splits in two• Each embryo then develops independently

Figure 9.10Identical twins: © Barbara Penoyar/Getty Images RF

Page 45: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Meiosis Generates Variability

Section 9.5

Fraternal twins:two sperm cells fertilize two separate egg cells

Figure 9.10Fraternal twins: © Image Source Black/ Getty Images RF

Page 46: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Many sets of triplets consist of a “pair and a spare;” that is, two identical babies and one non-identical baby. Producing this arrangement requires ___ sperm and ___ eggs.

A. 2 … 2B. 1 … 3C. 3 … 1D. 2 … 3

Flower: © Doug Sherman/Geofile/RF

Page 47: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Karyotyping

Page 48: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Human Karyotypes

Page 49: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.20A_s3

Nondisjunction

MEIOSIS I

MEIOSIS II

Normalmeiosis II

Gametes

Number ofchromosomes

Abnormal gametes

n 1 n 1 n 1 n 1

Nondisjunction

Page 50: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.20B_s3

Normalmeiosis I

MEIOSIS I

MEIOSIS II

Nondisjunction

Abnormal gametes Normal gametes

n 1 n 1 n n

Nondisjunction

Page 51: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Nondisjunction

Page 52: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Nondisjuction & Fertilization

Page 53: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.19A

Trisomy 21

Page 54: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Downs Syndrome & Maternal Age

Page 55: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.23A

Deletion

Duplication

Inversion

Reciprocal translocation

Homologous

chromosomes Nonhomologouschromosomes

Chromosomal Alterations

Page 56: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Figure 8.23B

Chromosome 9

Chromosome 22 Reciprocaltranslocation

“Philadelphia chromosome”

Activated cancer-causing gene

Chromosomal AlterationsReciprocal translocation

Page 57: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Errors Also Occur Within Chromosomes

Section 9.7 Figure 9.14

Mutations in chromosome structure can have major effects on an organism.

Chromosomes: © Addenbrookes Hospital/Science Source

Page 58: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Klinefelter’s Syndrome

Page 59: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Klinefelter’s Syndrome

Page 60: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Turner’s Syndrome

Page 61: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

XYY – Super Male

Page 62: Chapter 9 · Chapter 9 Sexual Reproduction and Meiosis ... The photo below shows two chromosomes ... Section 9.3 Human female karyotype:

Number of chromosomalduplications

Number of cell divisions

Number of daughter cells

produced

Number of chromosomes in

the daughter cells

How the chromosomes line

up during metaphase

Genetic relationship of the

daughter cells to the parent cell

Functions performed in thehuman body

Mitosis Meiosis