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Copyright 2009, John Wiley & Sons, Inc. Chapter 2: The Chemical Level of Organization

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  • Copyright 2009, John Wiley & Sons, Inc.

    Chapter 2:

    The Chemical Level of

    Organization

  • Question

    Of the following functions, the major propose of

    RNA is to

    A. Function in the synthesis of protein.

    B. Transmit genetic information to offspring.

    C. Form the genes of higher organisms.

    D. Act as a pattern or blueprint to form DNA.

    Copyright 2009, John Wiley & Sons, Inc.

  • Question

    In a DNA molecule, adenine always pairs with

    what other nitrogenous base?

    a) Thymine

    b) Cytosine

    c) Guanine

    d) The make up of pairs varies

    Copyright 2009, John Wiley & Sons, Inc.

  • Terms to know

    1. Carbohydrates

    2. Lipids

    3. Phospholipids

    4. Steroids

    5. Proteins

    6. Enzymes

    7. DNA

    8. RNA

    9. ATP

    Copyright 2009, John Wiley & Sons, Inc.

  • Presentation Preview

    Requirements:

    Title slide with your name, date, and period.

    Create one slide for each term

    Include a simple definition of the term (2-3

    sentences)

    Include a picture that helps explain

    Also include the website you received the

    information from.

    Submit on Google Classroom! Copyright 2009, John Wiley & Sons, Inc.

  • Discussion Questions

    1. Explain the function of carbohydrates. Provide several examples of them.

    2. Describe polysaccharides. How does the human body use them?

    3. Explain what a lipid is. Common lipids include triglycerides and

    phospholipids, what are these lipids and what is their function?

    4. Explain what a steroid is. What are their uses in the human body?

    5. What is a protein? What are they made out of? What are they used for?

    6. Explain the function of enzymes. Provide examples of some and what they

    are used for.

    7. What is DNA? What is it made up of? Where do you find it?

    8. What is RNA used for? How is it different from DNA?

    9. Explain what Adenosine Triphosphate (ATP) is. What is it made up of?

    Copyright 2009, John Wiley & Sons, Inc.

  • Discussion Questions 2

    1. Some amateur and professional athletes take anabolic steroids to help them “bulk up” or build strength.

    The health risks of this practice are extensively documented. Apart from health considerations, how do

    you feel about the use of chemicals to enhance athletic performance? Do you think an athlete who takes

    anabolic steroids is cheating, or is the use of such chemicals just part of the preparation required to

    succeed in a competitive sport? Defend your answer.

    2. Given the materials commonly found in a kitchen, explain how one could distinguish between a protein

    and a lipid.

    3. A student is given two unlabeled substances, one a typical phospholipid and one a typical protein. She is

    asked to determine which substance is the protein and which is the phospholipid. The available technique

    in her lab will allow her to determine the elements in each sample. How can she identify each substance?

    4. Explain why heat, pH changes, and other environmental changes can interfere with a protein’s function.

    5. How can a cell make many different kinds of protein out of only 20 amino acids?

    6. A few human enzymes work best at a very low pH of about 2. Where in the body do you think these

    enzymes are located? What kind of enzymes do you think are found here?

    7. Why do phospholipids tend to organize together into a bilayer in an aqueous (water based) environment?

    8. Explain how each of the following food preservation methods would interfere with a microbe’s enzyme

    activity and ability to break down food: canning (heating), freezing, pickling (soaking in acetic acid),

    salting.

    9. A genetic mutation can change the primary structure of a protein. How can this destroy the proteins

    function?

    Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Carbohydrates

    Carbohydrates provide

    most of the energy needed

    for life and include sugar.

    Some carbohydrates are

    used to build structures and

    to generate ATP. Others

    are stored.

    Three types:

    monosaccharides,

    disaccharides, and

    polysaccharides

  • Copyright 2009, John Wiley & Sons, Inc.

    Polysaccharides

    Polysaccharides are the largest carbohydrates and may contain hundreds of monosaccharides.

    The principal polysaccharide in the human body is glycogen, which is stored in the liver or in muscle.

    When blood sugar level drops, the liver hydrolyzes glycogen to yield glucose which is released from the liver into the blood

  • Copyright 2009, John Wiley & Sons, Inc.

    Lipids Lipids, like carbohydrates, contain carbon, hydrogen, and

    oxygen.

    Hydrophobic (do not mix with water)

    Triglycerides are the most plentiful lipids in the body and they

    provide energy.

    Phospholipids are important membrane

    components.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Steroids

    Steroids have four rings of carbon atoms.

    Examples include hormones, vitamins and

    cholesterol.

    cholesterol, with cholesterol serving as an

    important component of cell membrane.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Proteins Constructed from combinations of 20 base amino acids.

    dipeptides formed from 2 amino acids joined by a

    covalent bond (called a peptide bond).

    polypeptides chains can be from 10 to 2000 amino

    acids.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Enzymes = Catalyst

    Catalyst - a

    substance that

    increases the

    rate of a

    chemical reaction

    Enzymes speed

    up chemical

    reactions.

  • Copyright 2009, John Wiley & Sons, Inc.

    DNA

    Deoxyribonucleic acid

    (DNA) forms the genetic

    code inside each cell and

    thereby regulates most of

    the activities that take

    place in our cells

    throughout a lifetime.

    The basic units of nucleic

    acids are nucleotides,

    composed of a nitrogen

    base, sugar, and a

    phosphate group.

  • Copyright 2009, John Wiley & Sons, Inc.

    RNA Structure

    Ribonucleic acid (RNA) relays instructions from the

    genes in the cell’s nucleus to guide each cell’s

    assembly of amino acids into proteins by the

    ribosomes.

    Differs from DNA

    single stranded

    ribose sugar not deoxyribose sugar

    Contains uracil instead of thymine

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Adenosine Triphosphate (ATP)

    Molecule that acts as the temporarymolecular storage of energy

  • Review

    Video Review: http://youtu.be/H8WJ2KENlK0

    Another Review:

    http://www.youtube.com/watch?v=QWf2jcznL

    sY

    Copyright 2009, John Wiley & Sons, Inc.

    http://youtu.be/H8WJ2KENlK0http://www.youtube.com/watch?v=QWf2jcznLsY

  • Question

    Which type of lipid is a major component of cell

    membranes?

    a) Fatty acids

    b) Triglycerides

    c) Vitamin D

    d) Phospholipids

    Copyright 2009, John Wiley & Sons, Inc.

  • Question

    The sequence of amino acids found in a protein

    makes up which level of organization?

    a) Quaternary

    b) Primary

    c) Secondary

    d) Tertiary

    Copyright 2009, John Wiley & Sons, Inc.