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    Change your life in bigger ways

    This article is fantastic. Read it, READ IT, and

    change how you look at life NOW! I get somany submissions on tumblr from unhappy

    women who want to be successful, this article

    might get you thinking a little differently and

    help you make your drive, health and success

    better.

    Meaning Is Healthier Than Happiness

    People who are happy but have little-to-no

    sense of meaning in their lives have the same

    gene expression patterns as people who are

    enduring chronic adversity.

    EMILY ESFAHANI SMITH

    AUG 1 2013, 8:00 AM ET

    For at least the last decade, the happiness

    craze has been building. In the last three

    months alone, over 1,000 books on happinesswere released on Amazon, including Happy

    Money, Happy-People-Pills For All, and, for

    those just starting out, Happiness for

    Beginners.

    http://ilovewildfox.com/iloveyouwildfox/2013/9/8/change-your-life-in-bigger-wayshttp://www.theatlantic.com/emily-esfahani-smith/http://www.theatlantic.com/emily-esfahani-smith/http://ilovewildfox.com/iloveyouwildfox/2013/9/8/change-your-life-in-bigger-ways
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    One of the consistent claims of books like

    these is that happiness is associated with all

    sorts of good life outcomes, includingmost

    promisinglygood health. Many studies have

    noted the connection between a happy mind

    and a healthy bodythe happier you are, the

    better health outcomes we seem to have. In a

    meta-analysis (overview) of 150 studies on this

    topic, researchers put it like this: Inductions

    of well-being lead to healthy functioning, and

    inductions of ill-being lead to compromised

    health.

    Being happy is about feeling good. Meaning is

    derived from contributing to others or to

    society in a bigger way.

    But a new study, just published in

    the Proceedings of the National Academy of

    Sciences(PNAS) challenges the rosy picture.

    Happiness may not be as good for the body as

    researchers thought. It might even be bad.

    Of course, its important to first

    define happiness. A few months ago, I wrote

    a piece called Theres More to Life Than Being

    http://www.cnbc.pt/jpmatos/03.%20Howel.pdfhttp://www.pnas.org/content/early/2013/07/25/1305419110.shorthttp://www.theatlantic.com/health/archive/2013/01/theres-more-to-life-than-being-happy/266805/http://www.theatlantic.com/health/archive/2013/01/theres-more-to-life-than-being-happy/266805/http://www.pnas.org/content/early/2013/07/25/1305419110.shorthttp://www.cnbc.pt/jpmatos/03.%20Howel.pdf
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    Happy about a psychology study that dug into

    what happiness really means to people. It

    specifically explored the difference between a

    meaningful life and a happy life.

    It seems strange that there would be a

    difference at all. But the researchers, who

    looked at a large sample of people over a

    month-long period, found that happiness is

    associated with selfish taking behavior andthat having a sense of meaning in life is

    associated with selfless giving behavior.

    "Happiness without meaning characterizes a

    relatively shallow, self-absorbed or even

    selfish life, in which things go well, needs and

    desire are easily satisfied, and difficult or

    taxing entanglements are avoided," the

    authors of the study wrote. "If anything, pure

    happiness is linked to not helping others in

    need. While being happy is about feeling good,

    meaning is derived from contributing to others

    or to society in a bigger way. As Roy

    Baumeister, one of the researchers, told me,

    "Partly what we do as human beings is to take

    care of others and contribute to others. This

    http://faculty-gsb.stanford.edu/aaker/pages/documents/SomeKeyDifferencesHappyLifeMeaningfulLife_2012.pdfhttp://faculty-gsb.stanford.edu/aaker/pages/documents/SomeKeyDifferencesHappyLifeMeaningfulLife_2012.pdf
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    makes life meaningful but it does not

    necessarily make us happy.

    The new PNAS study also sheds light on thedifference between meaning and happiness,

    but on the biological level. Barbara

    Fredrickson, a psychological researcher who

    specializes in positive emotions at the

    University of North Carolina-Chapel Hill, and

    Steve Cole, a genetics and psychiatricresearcher at UCLA, examined the self-

    reported levels of happiness and meaning in 80

    research subjects.

    Meaning was defined as an orientation to

    something bigger than the self.

    Happiness was defined, as in the earlier study,

    byfeeling good. The researchers measured

    happiness by asking subjects questions like

    How often did you feel happy? How often did

    you feel interested in life? and How often did

    you feel satisfied? The more strongly peopleendorsed these measures of hedonic well-

    being, or pleasure, the higher they scored on

    happiness.

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    Meaning was defined as an orientation to

    something bigger than the self. They measured

    meaning by asking questions like How often

    did you feel that your life has a sense of

    direction or meaning to it?, How often did

    you feel that you had something to contribute

    to society?, and How often did you feel that

    you belonged to a community/social group?

    The more people endorsed these measures of

    eudaimonic well-beingor, simply put,

    virtuethe more meaning they felt in life.

    After noting the sense of meaning and

    happiness that each subject had, Fredrickson

    and Cole, with their research colleagues,

    looked at the ways certain genes expressedthemselves in each of the participants. Like

    neuroscientists who use fMRI scanning to

    determine how regions in the brain respond to

    different stimuli, Cole and Fredrickson are

    interested in how the body, at the genetic

    level, responds to feelings of happiness andmeaning.

    Coles past work has linked various kinds of

    chronic adversity to a particular gene

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    expression pattern. When people feel lonely,

    are grieving the loss of a loved one, or are

    struggling to make ends meet, their bodies go

    into threat mode. This triggers the

    activation of a stress-related gene pattern that

    has two features: an increase in the activity of

    proinflammatory genes and a decrease in the

    activity of genes involved in anti-viral

    responses.

    You have a forward-looking immune system,

    Fredrickson told me, If you have a long track

    record of adversity, it prepares you for

    bacterial infections. For our ancestors,

    loneliness and adversity were associated with

    bacterial infections from wounds withpredators and fights with conspecifics. On the

    other hand, if you are doing well and having a

    lot of healthy social connections, your immune

    system shifts forward to prepare you for

    viruses, which youre more likely to contract if

    you're interacting with a lot of people.

    What does this have to do with happiness?

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    Cole and Fredrickson found that people who

    are happy but have little to no sense of

    meaning in their livesproverbially, simply

    here for the partyhave the same gene

    expression patterns as people who are

    responding to and enduring chronic adversity.

    That is, the bodies of these happy people are

    preparing them for bacterial threats by

    activating the pro-inflammatory response.

    Chronic inflammation is, of course, associated

    with major illnesses like heart disease and

    various cancers.

    Empty positive emotionslike the kind

    people experience during manic episodes or

    artificially induced euphoria from alcohol anddrugsare about as good for you for as

    adversity, says Fredrickson.

    Its important to understand that for many

    people, a sense of meaning and happiness in

    life overlap; many people score jointly high (or

    jointly low) on the happiness and meaning

    measures in the study. But for many others,

    there is a dissonancethey feel that they are

    low on happiness and high on meaning or that

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    their lives are very high in happiness, but low

    in meaning. This last group, which has the

    gene expression pattern associated with

    adversity, formed a whopping 75 percent of

    study participants. Only one quarter of the

    study participants had what the researchers

    call eudaimonic predominancethat is,

    their sense of meaning outpaced their feelings

    of happiness.

    This is too bad given the more beneficial gene

    expression pattern associated with

    meaningfulness. People whose levels of

    happiness and meaning line up, and people

    who have a strong sense of meaning but are

    not necessarily happy, showed a deactivationof the adversity stress response. Their bodies

    were not preparing them for the bacterial

    infections that we get when we are alone or in

    trouble, but for the viral infections we get

    when surrounded by a lot of other people.

    Fredricksons past research, described in her

    two books, Positivityand Love 2.0, has

    mapped the benefits of positive emotions in

    individuals. She has found that positive

    http://www.theatlantic.com/sexes/archive/2013/01/theres-no-such-thing-as-everlasting-love-according-to-science/267199/http://www.theatlantic.com/sexes/archive/2013/01/theres-no-such-thing-as-everlasting-love-according-to-science/267199/
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    emotions broaden a persons perspective

    and buffers people against adversity. So it was

    surprising to her that hedonistic well-being,

    which is associated with positive emotions and

    pleasure, did so badly in this study compared

    with eudaimonic well-being.

    Its not the amount of hedonic happiness

    thats a problem, Fredrickson tells me, Its

    that its not matched by eudaimonic well-being. Its great when both are in step. But if

    you have more hedonic well-being than would

    be expected, thats when this [gene] pattern

    thats akin to adversity emerged.

    The terms hedonism and eudaimonism bring to

    mind the great philosophical debate, which has

    shaped Western civilization for over 2,000

    years, about the nature of the good life. Does

    happiness lie in feeling good, as hedonists

    think, or in doing and being good, as Aristotle

    and his intellectual descendants, the virtue

    ethicists, think? From the evidence of this

    study, it seems that feeling good is not

    enough. People need meaning to thrive. In the

    words of Carl Jung, The least of things with a

    http://www.theatlantic.com/health/archive/2013/03/the-benefits-of-optimism-are-real/273306/http://www.theatlantic.com/health/archive/2013/03/the-benefits-of-optimism-are-real/273306/
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    meaning is worth more in life than the greatest

    of things without it. Jungs wisdom certainly

    seems to apply to our bodies, if not also to

    ourhearts and our minds.

    And another amazing one from the Economist

    THE Greek founders of philosophy constantly

    debated how best to live the good life. Some

    contended that personal pleasure is the key.

    Others pointed out that serving society and

    finding purpose is vital. Socrates was in the

    latter camp, fiercely arguing that an unvirtuous

    person could not be happy, and that a virtuous

    person could not fail to be happy. These days,

    psychologists tend to regard that point as

    moot, since self-serving hedonic pleasures

    generate the same sorts of good feelings as

    those generated by serving some greater

    eudaimonic purpose. However, a study just

    published in the Proceedings of the National

    Academy of Sciences, by Barbara Fredrickson,

    a psychologist at the University of North

    http://www.theatlantic.com/health/archive/2013/01/theres-more-to-life-than-being-happy/266805/http://www.theatlantic.com/health/archive/2013/01/theres-more-to-life-than-being-happy/266805/
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    Carolina, Chapel Hill, and her colleagues

    suggests Socrates had a point. Though both

    hedonic and eudaimonic behaviour bring

    pleasure, the eudaimonic sort also brings

    health.

    Dr Fredrickson, an expert on positive

    emotions, has long known that happiness

    benefits health and leads to longer lives.

    Similarly, she knows that both hedonic andeudaimonic pleasures generate feelings that

    people describe as happiness. A simple

    syllogism, therefore, suggests happiness does

    indeed bring health and longevity. But,

    because of the overlap between the happiness-

    generating properties of both hedonic andeudaimonic pleasures, she had until she

    conducted this study found it impossible to

    determine whether both are able improve

    physical health and longevity, or whether only

    one of them can.

    To solve the puzzle, she and a team of

    genomics researchers led by Steven Cole of

    the University of California, Los Angeles,

    recruited 84 volunteers for an experiment that

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    examined genes associated with health while

    simultaneously probing happiness in a way

    that would tease apart hedonic and

    eudaimonic well-being. The team interviewed

    participants over the phone to make sure none

    suffered from any chronic illness or disability

    (four were eliminated this way). The rest were

    given online questionnaires in which they were

    asked questions that probed their happiness.

    These included, In the past week how often

    did you feel happy? and, How often did you

    feel satisfied? both of which were intended to

    assess hedonic well being. To assess

    eudaimonic well being they asked questions

    like, In the past week how often did you feel

    that your life had a sense of direction or

    meaning to it? and How often did you feel

    that you had something to contribute to

    society? The answers to these questions

    could score from nought to five points. Nought

    indicated never. Five indicated every day.

    The questionnaires also collected information

    on participants age, sex, race, smoking,

    alcohol consumption and recent symptoms of

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    minor illness, like headaches and upset

    stomachs.

    In addition to the answers to the questions,participants provided the team with a 20cc

    sample of blood. These samples were

    centrifuged to isolate the immune-system cells

    in them, and those cells were then analysed to

    see which genes were active.

    At this, genetic, level, Dr Fredrickson and Dr

    Cole report, the two forms of happiness could

    hardly be more different. In volunteers who

    scored strongly for hedonic well-being and

    weakly for eudaimonic well-being

    inflammation-causing genes were 20% more

    active than average, and genes associated

    with the production of virus-attacking

    antibodies 20% less active. In contrast, in

    those who were the other way round, genes

    associated with the production of interferons

    (proteins that support communication during

    immune-system responses) were 10% more

    active and antibody genes 30% more active.

    Eudaimonic pleasure thus looks as though it is

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    good for the health, while hedonic pleasure is

    bad.

    Of course, these are extreme cases. In thosewho indulge in both forms of pleasure seeking

    the one effect cancels out the other. And it is

    possilbe, at least in theory, that causation runs

    in the opposite direction: people with

    particular patterns of gene expression could

    be healthier and thus, perhaps, take a longerview of life, which might in turn be conducive

    to eudaimonia. But differences of this sort in

    expression patterns within a single cell type

    are usually the result of signals to the cell,

    rather than being endogenouswhich they

    would have to be if they were the underlyingcause. That said, eudaimonia and health-giving

    expression patterns could be independent

    outcomes of some third, unidentified factor.

    Nevertheless, if these molecular results do

    translate into bodily health in the way that

    might be predicted, it suggest Socrates was

    right, and that selfless, public-spirited

    individuals and selfish pleasure-seekers alike

    will receive their rewards and punishments

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    here on Earth, without the need for the threat

    or promise of an afterlife.

    Thanks Sam Y of LA's "All Out Effort" for the

    tip!