1.PRAYER TO BE A NURSE To be a nurse is to walk with God, Along thepath that our Master trod; To soothe the achingsof human pain, To faithfully serve for littlegain, To lovingly do the kindly deed, A cup ofwater to one in need, A tender hand on afevered brow, A word of cheer to those livingnow; To reach the souls through its bodys woeOh, this is the way that Jesus would go.Oh, white-capped nurses with hearts sotrue, Our Great Physician is working throughyou.

2. Adrenergic Agents and Adrenergic BlockersBy Kerry FiteAUTONOMIC NERVOUS SYSTEM AGENTS 3. PARASYMPATHETIC AND SYMPATHETICNERVOUS SYSTEMS 4. ADRENERGIC AGONISTS Function of adrenergics 5. ADRENERGIC AGONISTS (CONTD) Effects of adrenergic receptor sites Alpha1receptors in Vascular tissuesstimulated = Increasescardiac contractility, BP is increased, vasoconstriction, circulation is improved Dilates pupils, decrease salivary gland secretion Increase bladder & prostate contraction Alpha2 = Inhibits norepinephrine release Promote vasodilation and decreased BP DecreaseGI motility and tone 6. ADRENERGIC AGONISTS (CONTD) Effects of adrenergic receptor sites Beta1 Found in the heart Increases cardiac contractility, heart rate Increases BP by effects on the kidneys renin secretion. Beta2 found primarily in the smooth muscleof the lungs Bronchodilation Decrease Gastrointestinal, relax uterine muscle Increases blood flow in skeletal muscles Increases blood glucose because liver releases stored suger Dopaminergic Receptor sites located in the renal system andthe real arteries are dilated when the receptors are stimulated Vasodilation Increases blood flow 7. ADRENERGICS AND DISEASEBeta Agonist are used to treat asthma and chronic obstructive lung disease and manage pregnancyBeta-1 are primarily used in heartBeta -2 Agonist stimulate bronchodilatation in the treatment of lung disease. 8. CLASSIFICATION OF ADRENERGICAGONISTS/SYMPATHOMIMETICS Direct-acting - Endogenous Indirect-acting StimulatesEndogenous Release Mixed-actingEphedrineEpinephrinePrototype Drug 9. CATECHOLAMINES Chemical Structures of a substancethat can produce a sympthomemticresponse Endogenous= norepinepherine epinepherine, dopamine Exdogenous Catacholimines 10. EPINEPHRINE (ADRENALIN) Nonselective Action Alpha1increases the blood pressure Beta1 increases heart rate Beta2 promotes bronchodilation Pharmacodynamics: Frequentlyused in emergencies to treat lifethreatening anaphylaxis IE BeeStings. It is also used as a potentinotropic drug in a CODE. 11. ALBUTEROL (PROVENTIL) Selective Actson beta2-adrenergic receptors Promotes bronchodilation Uses Treatsbronchospasm, asthma,bronchitis, COPD Side effects/adverse reactions Tremors, nervousness, restlessness Dizziness, reflex tachycardia 12. Adrenergic AgonistNursing Process Assessment NusingDX Planning Nursing Interventions Client Teaching Evaluation 13. ADRENERGIC BLOCKERS (ANTAGONIST) Block effects of adrenergic agonistneurotransmitter Block alpha and beta receptor sites 1. Directly by occupying receptors 2. Indirectly by inhibiting release of neurotransmitters epinephrine and norepinephrine, dopamine 14. ALPHA ADRENERGIC BLOCKERS Nonselective Acting Alpha 1 and Alpha 2 are selected Selective Blockers cause vasodilation, decreasesblood pressure. Used to treat BPH and PVD(Raynauds Disease) 15. BETA-ADRENERGIC BLOCKERS Beta-blockers DecreaseBP and Pulse Nonselective beta blockers block1. Blocks beta1 = Decrease BP and Pulse2. Blocks beta2 = Bronchostriction Uses Angina, cardiacdysrhythmias, hypertension, heartfailure, migraine headache prophelaxis 16. NONSELECTIVE BETA BLOCKERS Must be used with extreme caution in COPDand Asthma patients. Although Propranolol is used still used todayit is used sparingly because of the multitudeof side effects. 17. BETA-ADRENERGIC BLOCKERS (CONTD) Nonselective propranolol Contraindications COPD and Asthma Side Effects Weightgain, impotence, decreased libido, Drug interactions Decreased drug effects with NSAIDs, barbiturates, caffeine P R o T O 18. ATENOLOL Beta Adrenergic blocker Contraindicated in Sinus Bradycardia, Heartblock, bronchospasm Treat Hypertension, angina, MI Side effects:Drawsiness, dizziness, depression, weakness, N/D/V leg pain, sexual side effects Adverse Reaction:bradycardia, hypotension, maskinghypoglycemia, 19. ATENOLOL Pharmacokinetics Phamacodynamicsknow 20. THE END