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QuickTime™ and a decompressor are needed to see this picture. Inheritance Pattern Autosomal recessive Needs two parent carriers

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Page 1: Cftr

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Inheritance Pattern

Autosomal recessive

Needs two parent carriers

Page 2: Cftr

Phenotypic Expression

salty skin bad

coughing with phlegm

frequent lung infections

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Page 3: Cftr

Normal Functions

Anion Channel

Absorption and secretion

Page 4: Cftr

Abnormal Functions

Lung is unable to maintain a sterile surface

Cl- conductance stopped

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Locus

Chromosome 7

7q31.2 QuickTime™ and a decompressor

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Medical Concerns and Treatments

Problems in lungs, pancreas, liver, intestines, sinuses, and sex organs

Has no cure

Must be treated in hospitals

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Prevalence

Approximately 30,000 children and adults in the United States

Most common in Caucasians but may affect all races

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Page 8: Cftr

Works Cited

"Cystic Fibrosis - Genetics Home Reference." Genetics Home Reference - Your Guide to Understanding Genetic Conditions. 2011. Web. 04 Jan. 2011. <http://ghr.nlm.nih.gov/condition/cystic-fibrosis>.

"Cystic Fibrosis Foundation – About Cystic Fibrosis." Cystic Fibrosis Foundation - Home. Web. 04 Jan. 2011. <http://www.cff.org/AboutCF/>.

"Cystic Fibrosis Foundation – Frequently Asked Questions." Cystic Fibrosis Foundation - Home. 2009. Web. 04 Jan. 2011. <http://www.cff.org/AboutCF/Faqs/#>.

"Cystic Fibrosis." Google Health. 2010. Web. 4 Jan. 2011. <https://health.google.com/health/ref/Cystic+fibrosis>.

"Cystic Fibrosis Symptoms, Causes, Treatment - How Is Cystic Fibrosis Treated on MedicineNet." MedicineNet.com. 2010. Web. 04 Jan. 2011. <http://www.medicinenet.com/cystic_fibrosis/page5.htm>.

Wine, Jeffrey J. "Cystic Fibrosis." Stanford University. 2003. Web. 04 Jan. 2011. <http://www.stanford.edu/class/psych121/humangenome-CF.htm>.

"Cystic Fibrosis Gene." Oak Ridge National Laboratory. 2003. Web. 04 Jan. 2011. <http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/cftr.shtml>.


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