Center for Biological and Environmental Nanotechnology(NSEC: EEC-0118007)

Vicki L. Colvin, James M. Tour, Rebekah Drezek, Jennifer West, Jason Hafner, Pedro Alvarez, Qilin Li, Jun Lou, Mason Tomson, John Hutchinson, Carolyn Nichol, Kristen M. Kulinowski (Rice University) , Jay L. Conyers (UT Health Science Center)

Nano Teacher-Training Course Goes the Distance (Hutchinson, Nichol)

Nanotubes Scavenge Free Radicals (Tour, Conyers)

The GoodNanoGuide: A wiki for the safe handling of nanomaterials (Kulinowski)

•VIEW•COMMENT•CONTRIBUTE

http://goodnanoguide.org

•Protected Internet site on occupational practices for the safe handling of nanomaterials•Multiple stakeholders contribute, share and discuss information•Modern, interactive, up-to-date

Nanoparticles Improve Detection of Cancer Cells (Drezek, West, Colvin, Hafner)

Pilot Project To Test Nanoparticle Water Treatment (Alvarez, Colvin, Li, Lou, Tomson)

Creating sustainable nanotechnologies that improve human health and the environment

(a.)

(b.)

(c.)

451-483 nm 483-515 nm 515-547 nm 558-579 nm 590-644 nm

Nanoshell-tagged cancer cells (top) are much easier to detect than unlabelled cells (bottom). Nanotechnology 19 (2008) 315102

• Immunotargeted gold nanoshells used as contrast agents for in vitro two-photon microscopy

• Entire procedure can be done in 10 minutes

• Initial study on missed cancer after surgical resection is planned with MD Anderson Cancer Center

• Ultrashort nanotubes functionalized with derivatives of the phenolic antioxidant, butylated hydroxytoluene (BHT).

• Oxygen radical scavenging ability measured via oxygen radical absorbance capacity (ORAC) assay

• Both nonfunctionalized and BHT derivatized SWCNTs have little or no deleterious effect on cell viability.

Ultrashort nanotube modified to become free-radical scavenger

• 1st known test of nanoparticles in municipal water and wastewater treatment• Test bed will explore (1) using a sand-nanomagnetite in-line filter to remove

arsenic in a well field, and (2) wastewater photo-disinfection with fullerenes• Partnership with Municipal Water and Sewerage Authority of Guanajuato.

Guanajuato, Mexico(UN Heritage, pop. 80,000)

Wastewater Treatment Plant Grad Student Jesse Farrell

• Teacher-training course exposes teachers to fundamental concepts in nanotechnology

• Partnership with CU’s Alliance for Technology, Learning and Society Institute permits course to be offered via videoconference and web.

• Spring 2009 offering reaches 47 teachers in Texas and Colorado

• Additional 6 participate from home via web

Course offered simultaneously in Texas (Nichol, left) and Colorado (Hutchinson, right)

• Audience response system (“clickers”) employed to enhance active learning