cell division 2
DESCRIPTION
TRANSCRIPT
Edited by Hasimah Azit
The form of cell divisioncell division by which gametes, gametes, with halfhalf the number of chromosomes, chromosomes, are produced.
Diploid (2n) Diploid (2n) haploid (n)haploid (n)
MeiosisMeiosis is sexual reproduction.sexual reproduction.
Two divisionsTwo divisions (meiosis I meiosis I and meiosis meiosis IIII).
Sex cells Sex cells divide to produce gametesgametes (sperm or egg)(sperm or egg).
GametesGametes have halfhalf the # of chromosomeschromosomes.
Occurs only in gonads (testes or Occurs only in gonads (testes or ovaries).ovaries).
Male: spermatogenesisMale: spermatogenesisFemale: oogenesisFemale: oogenesis
MeiosisMeiosis is similar to mitosismitosis with some chromosomal differences.
2n=46
humansex cell
diploid (2n)
n=23
n=23
meiosis I
n=23
n=23
n=23
n=23
sperm
haploid (n)
meiosis II
Similar to mitosismitosis interphase.
ChromosomesChromosomes replicate (S phase).(S phase).
Each duplicated chromosomechromosome consist of two identical sister chromatidschromatids attached at their centromerescentromeres.
CentrioleCentriole pairs also replicate.
NucleusNucleus and nucleolusnucleolus visible.
nuclear membrane
nucleolus
cell membrane
chromatin
Cell division Cell division that reduces the chromosomechromosome number by one-half.one-half.
four phasesfour phases:a.a. prophase Iprophase Ib.b. metaphase Imetaphase Ic.c. anaphase Ianaphase Id.d. telophase Itelophase I
Longest and most complex phase Longest and most complex phase (90%).(90%).
ChromosomesChromosomes condense. SynapsisSynapsis occurs: homologous homologous
chromosomes chromosomes come together to form a tetradtetrad.
TetradTetrad is two chromosomeschromosomes or four chromatidschromatids (sister and nonsister chromatids).
Homologous chromosomes
sister chromatids sister chromatidsTetrad
Pair of chromosomeschromosomes (maternalmaternal and paternalpaternal) that are similar in shape and size.
Homologous pairs (tetrads) (tetrads) carry genes controlling the same inherited traits.
Each locuslocus (position of a gene) (position of a gene) is in the same position on homologues.
Humans have 23 pairs of homologous homologous chromosomes.chromosomes.
a. 22 pairs of autosomesautosomesb. 01 pair of sex chromosomessex chromosomes
Paternal Maternal
eye color locus
eye color locus
hair color locus
hair color locus
Crossing over (variation) Crossing over (variation) may occur between nonsister chromatidschromatids at the chiasmatachiasmata.
Crossing overCrossing over: segments of nonsister chromatidschromatids break and reattach to the other chromatidchromatid.
Chiasmata (chiasma) Chiasmata (chiasma) are the sites of crossing overcrossing over.
nonsister chromatids
chiasmata: site of crossing over
variation
Tetrad
XX chromosome - female XY chromosome - male
centriolesspindle fiber
asterfibers
Shortest phaseShortest phase TetradsTetrads align on the metaphase platemetaphase plate. INDEPENDENT ASSORTMENT OCCURS:INDEPENDENT ASSORTMENT OCCURS:
1. Orientation of homologous pair to poles is random.2. Variation3. Formula: 2n
Example:Example: 2n = 42n = 4then then n = 2 n = 2
thusthus 2 22 2 = 4 = 4 combinationscombinations
metaphase plate
OR
metaphase plate
Homologous chromosomes Homologous chromosomes separate and move towards the poles.
Sister chromatids Sister chromatids remain attached at their centromerescentromeres.
Each pole now has haploidhaploid set of chromosomeschromosomes.
CytokinesisCytokinesis occurs and two haploid daughter cells are formed.
No interphase II No interphase II (or very short - no more DNA DNA replicationreplication)
Remember: Meiosis II Remember: Meiosis II is similar to mitosismitosis
same as prophaseprophase in mitosismitosis
same as metaphasemetaphase in mitosismitosis
metaphase platemetaphase plate
same as anaphaseanaphase in mitosismitosis sister chromatids separatesister chromatids separate
Same as telophasetelophase in mitosismitosis. Nuclei form. CytokinesisCytokinesis occurs.
Remember:Remember: four haploid daughter four haploid daughter cells cells produced.produced.
gametes = sperm or egggametes = sperm or egg
2n=4
sex cell
diploid (2n)
n=2
n=2
meiosis I
n=2
n=2
n=2
n=2
sperm
haploid (n)
meiosis II
MEIOSIS
Important to population as the raw Important to population as the raw material for material for natural selectionnatural selection..
Question:Question:What are the three sexual What are the three sexual
sources ofsources ofgenetic variation? genetic variation?
1. crossing over (prophase I)1. crossing over (prophase I)
2. independent assortment 2. independent assortment (metaphase I)(metaphase I)
3. random fertilization3. random fertilization
Remember: variation is good!
The fusion of a spermsperm and eggegg to form a zygotezygote.
A zygote is a fertilized egg
n=23egg
sperm n=23
2n=46zygote
mitosis meiosis