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Page 1: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Cell BoundariesCell Boundariesand Human and Human

HealthHealth

Page 2: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Why is water balance so Why is water balance so important in cells?important in cells?

Among the poor Among the poor and especially in and especially in developing developing countries, diarrhea countries, diarrhea is a major killer. is a major killer.

Page 3: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Why is water balance so Why is water balance so important in cells?important in cells?

4 billion cases of 4 billion cases of diarrhea yearly diarrhea yearly

2.2 million deaths -2.2 million deaths -many under the many under the age of 5age of 5

That’s 4 deaths That’s 4 deaths every minuteevery minute

Page 4: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

How do diarrheal diseases How do diarrheal diseases spread?spread?

The Story of Cholera

Page 5: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

http://picasaweb.google.com/dmeyer1usa/AfricaTrip2007/photo#5132143011588101730

Page 6: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 7: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

http://abandoned-orphaned.typepad.com/photos/uncategorized/2007/08/01/matharesewagerut.jpg

Page 8: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Why is there an increase in Why is there an increase in diarrheal diseases after natural diarrheal diseases after natural

disasters?disasters?

Page 9: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Pakistan - FloodingPakistan - Flooding

Page 10: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Haiti - EarthquakeHaiti - Earthquake

Page 11: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Indonesia - TsunamiIndonesia - Tsunami

Page 12: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Philippines - TyphoonPhilippines - Typhoon

What happens next?What happens next?

What are the biggest concerns of the What are the biggest concerns of the medical community?medical community?

Page 13: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

http://upload.wikimedia.org/wikipedia/commons/thumb/d/db/Vibrio_cholerae_01.jpg/800px-Vibrio_cholerae_01.jpg

http://microbewiki.kenyon.edu/images/a/a8/V_cholerae.jpg

Page 14: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

http://www.msf.org/source/countries/africa/angola/2006/cholera_tent.jpg

Page 15: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

To understand why diarrheal To understand why diarrheal disease can be so deadly – disease can be so deadly –

you have first have to you have first have to understand how healthy cells understand how healthy cells

manage water balance manage water balance

Page 16: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

http://www.medicalook.com/systems_images/Digestive_System.jpg

Page 17: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 18: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Cell MembraneCell Membrane

Page 19: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Moving in & out of cells by Moving in & out of cells by OSMOSISOSMOSIS

WaterWater molecules move from an area of molecules move from an area of high concentration to an area of low high concentration to an area of low concentration through a concentration through a semipermeable* semipermeable* membranemembrane

Does not require extra energyDoes not require extra energy

* Also called “* Also called “selectively permeableselectively permeable””

Page 20: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Effects of Osmosis on Blood CellsEffects of Osmosis on Blood Cells

Page 21: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Water Balance in CellsWater Balance in CellsWater Water

Outside CellOutside CellWater Inside Water Inside

CellCellWhich Way Which Way Will Water Will Water

Move?Move?

SameSame SameSameWater flow is Water flow is equal in and equal in and

out of cellout of cell

Less WaterLess Water More WaterMore Water Net water flow Net water flow out of cellout of cell

More WaterMore Water Less WaterLess Water Net water flow Net water flow into cellinto cell

Page 22: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Effect of Osmosis on Blood CellsEffect of Osmosis on Blood Cells

Page 23: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Body

Intestinal Lumen

Intestinal Cells

Salt

Salt

Salt

Page 24: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Salt

Salt

Salt

Salt

Salt

Page 25: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Skin

The Body Our Model System

Conical Tube

Dialysis Tube

Intestine

Page 26: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

One Dialysis Tube per Group

Conical Tube

= water

= salt

Control

One set-up/ClassExperimental

One set-up/Lab Group

Page 27: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 28: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 29: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Salt Solution Water

Page 30: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

What happened to the What happened to the dialysis tube with Salt? dialysis tube with Salt?

Why?Why?

Page 31: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Salt Solutio

n

Water

Water

Water

Water

OsmosisOsmosis

Page 32: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

How does your How does your experiment explain experiment explain cholera diarrhea?cholera diarrhea?

Page 33: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

Salt

Salt

Salt

Salt

SaltNet Flow of Water Net Flow of Water

Page 34: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

How would you treat the How would you treat the patient using osmosis?patient using osmosis?

Page 35: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 36: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

SaltSugar

SaltSugar

SaltSugar

SaltSugar

Page 37: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

SaltSugar

SaltSugar

SaltSugar

SaltSugar

SaltSugar

SaltSugar

SaltSugar

Net Flow of WaterNet Flow of Water

Page 38: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major

How do diarrheal diseases How do diarrheal diseases spread?spread?

The Story of CholeraThe Story of Cholera

Page 39: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major
Page 40: Cell Boundaries and Human Health. Why is water balance so important in cells? Among the poor and especially in developing countries, diarrhea is a major