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We invite your comments and suggestions about CCR connections.

Please email your feedback to [email protected].

Center for Cancer ResearchNational Cancer Institute | National Institutes of Health | Building 31 Room 3A11 | 31 Center Drive | Bethesda, MD 20892


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Table of Contents

E D I T O R I A L

03 Producing Scientic Synergism

N E W S

04 Introducing More Potent PARP Inhibitors

05 New Agents for Burkitts Lymphoma May Reduce Immunosuppression 06 Newly Identied Mechanism Links Obesity with Breast Cancer

07 Genomic Marker Better Informs Treatment Choices for CRPC

08 Recent CCR Awards

09 Staff News at CCR

10 CECB: Capturing Dynamic Changes in Chromatin

12 Novel Antibody Targets Glypican-3 in Liver Cancer

13 In Conversation: Research Fellow Junfang Ji, Ph.D.

F E A T U R E S

14 Virtual Entity Yields Real-Time Results 18 Training the Next Generation of Cancer Researchers 22 It Starts with a Choice: Cancer Cells and Their Decisions

to Replicate

C O M M E N T A R Y

26 Tackling Drug Resistance Mechanisms in the Stroma

14

Virtual EntityYields Real-TimeResults

FEATURE

18

Training the NextGeneration ofCancer Researchers

FEATURE

22

It Starts witha Choice

FEATURE

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Contributors:

K. Martin, M.S.

C. Schmidt, M.S.

S. Fox, B.A., B.S.W.

A. Wachter, B.A.

L. Brubaker

The mission of CCR is:

To inform and empower the entire cancer research

community by making breakthrough discoveries in

basic and clinical cancer research and by developing

them into novel therapeutic interventions for adults

and children aficted with cancer or infected with HIV.

http://home.ccr.cancer.gov/connections

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CCR connectionsis available online at http://home.ccr.cancer.gov/Connections

Web Sites with More Information about CCR

Center for Cancer Researchhttp://ccr.cancer.gov

Office of the Directorhttp://ccr.cancer.gov/about/OfficeDirector.aspx

Our Newshttp://ccr.cancer.gov/news

Office of Training and Educationhttp://ccr.cancer.gov/careers/OfficeEducation.aspx

Patient Information on Cancer and Clinical Trials

Open NCI Clinical Trialshttp://www.cancer.gov/clinicaltrials/search

How to Refer a Patienthttp://bethesdatrials.cancer.gov/health-care-professionals/index.aspx

NCI Cancer Information Servicehttp://www.cancer.gov/aboutnci/cis1-800-4-CANCER (1-800-422-6237)

Understanding Cancer Serieshttp://www.cancer.gov/cancertopics/understandingcancer

CCR Clinical Cancer Trials in Bethesda, MDhttp://bethesdatrials.cancer.gov

Additional Links

National Cancer Institute (NCI)http://www.cancer.gov

Working at NCIhttp://www.cancer.gov/aboutnci/working

National Institutes of Health (NIH)http://www.nih.gov

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NIH Publication No. 13-6211

Printed June 2013

ccr connections vol. 7, no. 1, 2013

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