catalyst magazine v 4.2

F09/W10

V 4.2Catalyst

Fall 2009/Winter 2010 Volume 4 • Issue 2

COLLEGE OF CHEMISTRY • U N I V E R S I T Y O F C A L I F O R N I A , B E R K E L E Y

Bringing it all back hometo Berkeley

A lab of her ownNew worlds for NMRPulling the veil from Mars

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all text and photos by michael barnesunless otherwise noted.

for online versions of our publicationsplease see: chemistry.berkeley.edu

© 2009, College of Chemistry, University of California,

Berkeley

COLLEGE OF CHEMISTRYUNIVERSITY OF CALIFORNIA, BERKELEY

deanRichard A. [email protected]

chair, department of chemistryMichael A. [email protected]

chair, department of chemical engineeringJeffrey A. [email protected]

acting assistant deanMindy Rex

510/642.9506; [email protected]

principal editorMichael Barnes


contributing editorKaren Elliott


alumni relations directorCamille M. Olufson


circulation coordinatorDorothy I. Read


designAlissar Rayes Design

printingUniversity of California Printing Services

Catalyst

ON THE COVER

The scientific artwork of Ming Hammond,assistant professor of chemistry, graces thisissues’s cover. For more on Hammond andher work with RNA, see page 6.

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Fall 2009 /Winter 2010Volume 4 • Issue 2

c o n t e n t s

3 DEAN’S DESK

4 CHEMISTRY NEWS

5 CHEMICAL ENGINEERING NEWS

6 FACULTY PROFILE

8 NEW WORLDS FOR NMR10 A VERY GOOD YEAR

14 ROLLING THE DICE

18 SPECIAL FEATURE: MARINER MISSION

20 NEW & NOTABLE

22 CLASS NOTES

24 IN MEMORIAM

29 ANNUAL REPORT

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College of Chemistry, UC Berkeley

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Fall 2009/Winter 2010 Catalyst

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d e a n ’ s d e s k

Students stop to chat on their way to class inPimentel Hall, named for beloved chemistryprofessor George C. Pimentel, who died in 1989(see page 18 for more on his work).

In past columns, I have described ourplans to renew our undergraduate teachingfacilities and curriculum. I’m happy toreport that, with initial funding in hand,we were able to move forward with renova-tions in the Hildebrand Student LearningCenter and Library, and we are nearingcompletion of three new presentationrooms for student discussions, seminarsand group meetings. The next phase of ourinitiative will involve renovating theundergraduate teaching laboratories anddeveloping an undergraduate advisingfacility.

The College is also pursuing federalresources for major new facilities andresearch projects. We have submitted alarge proposal to the National Institute of Standards and Technology to create theBerkeley Center for Attosecond Science, a complex of renovated laboratories inHildebrand Hall. Under the co-direction of professors Stephen Leone and DanielNeumark, the BCAS will be a world-classlaboratory for research into the fundamentaldynamics of electron motion in atoms andmolecules on the ultra-ultrafast time scaleof attoseconds.

We have also submitted a proposal to theNational Institutes of Health to establishthe Berkeley Single Cell Chemical Biology

New facilities for exploring thefrontiers of knowledge

Core Facility. Consisting of renovated labspace for cell biology, probe synthesis andcellular microscopy, the complex willenable researchers to understand livingcells on the molecular level. Co-directed by professors Matthew Francis andChristopher Chang, the facility will fostercollaboration among faculty membersfrom several academic departments.

We are progressing on the establishmentof the Berkeley Synthetic Biology Institute(SBI). The goal of the SBI is the productionof new biological components and systemsthat serve society’s needs. Building uponthe success of conventional biotechnology,synthetic biology is the next generation ofgenetic engineering, with the capacity todesign and produce cells, tissues, and ultimately even organisms with speciallytailored properties.

Inspired by the pioneering work of chemicalengineering professor Jay Keasling, theSBI is a collaborative effort between UCBerkeley, the California Institute forQuantitative Biosciences (QB3) and theLawrence Berkeley National Laboratorythat promises to sustain Berkeley’sinternational leadership in this importantnew field.

The College of Chemistry continues toexplore the frontier of knowledge andremains one of the world’s most dynamiccenters for scientific education and research.

RICHARD A. MATHIESDean and Gilbert N. Lewis Professor

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You are probably becoming somewhatimmune to news about the demise of theUniversity of California. Serious problemsremain, but as Mark Twain might havesaid, the news of the university’s death isgreatly exaggerated. We are ever vigilant,and we are finding workable solutions tothe budgetary strains.

There has been some good news, too. LastAugust, late on a Friday evening, I took onefinal look at my email and found a messagefrom a reporter from Inside Higher Ed. Hehad requested an interview with me for astory he was doing on job placement ratesfor female chemistry Ph.D. students (insidehighered.com/news/2009/08/17/chemistry).

My initial reaction was to erect a wallaround my weekend, but I decided to seewhat he had on his mind. The reporter hadattended the American Chemical Society(ACS) meeting in Washington, DC, andhad seen some very compelling data

presented by ACS board member ValerieKuck, a chemist who had worked in bothacademia and industry. The data showedthat among women earning chemistry

Ph.D. degrees, those from Berkeley hadthe most success in landing tenure-trackjobs at leading universities.

The numbers were stunning (and inciden-tally, quite good for our male students aswell). Kuck focused on women who obtainedPh.D. degrees between 1994 and 2003.She found that 54 percent of those hired, atotal of 63, came from just 12 top universi-ties. In that group, Berkeley’s star shonevery brightly—21 of the 63 hires werefrom Berkeley. Next closest were Caltechwith 7 and MIT with 6.

Women who completed a Berkeley postdocalso did well. Kuck noted, “I don’t havedirect evidence, but I have to believe thatthe environment at Berkeley is different. Ifwe look at the top six schools, why is it thatBerkeley all by itself can place almost half ofthe pool of women that got jobs? Somethingis going on.”

The reporter asked me what I thought wasgoing on. I admitted that, like Kuck, I did

not have direct data,but I commented onwhat I have seen inmy eight years atBerkeley (four ofthem as chair). Imentioned that wehave a critical massof female studentsand that our loftyranking sets a toneof quality for all. Ibelieve that our ded-ication to our publicmission adds anotherlevel of difference.But I think most

important is that our facult expect all students to thrive and succeed and that we convey that message to all of our students.

Perfection or close to it—right? Wrong!Although our female graduates are suc-cessful on the job market, our departmenthas had less success in attracting femaleapplicants trained by other institutions.The shortage of women in our facultyapplicant pool continues to dismay me.However, we have been successful recentlyin hiring talented female chemists, primarilyby selecting from among our own formerstudents and postdocs.

Our last two appointments were MichelleChang, who was formerly a postdoc in thelab of chemical engineer Jay Keasling, andMing Hammond, who was Paul Bartlett’sfinal Ph.D. student. In addition, Ting Xu,who earned her Ph.D. at UMass Amherst,holds a primary appointment in materialsscience and engineering and a jointappointment in chemistry.

These successes give me hope that we arebuilding some momentum toward moreequal gender representation, but only con-stant vigilance will keep us moving forward.So indeed, I am very pleased by recenttrends—but there remains much to be done.

by michael a. marletta

MICHAEL A. MARLETTAChair, Department of Chemistry, Joel B. HildebrandDistinguished Professor and Aldo DeBenedictisDistinguished Professor

Good news in the midst of many concerns

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Jim (not his real name) came strolling intomy office one morning. An alumnus show-ing up at my door is not unusual, thoughin Jim’s case the timing was interesting. Iwas staring at my computer screen, wonder-ing about the teaching and GSI (GraduateStudent Instructor) assignments for thecoming academic year.

Jim explained that he wanted to tell me howmuch he appreciated his time at Berkeley,some decades ago. We mused for a fewminutes about the people and times thatmarked his undergraduate studies. I knewseveral of his favorite professors, and weshared a few laughs. His next commentcaught me off-guard.

“You know, Professor Reimer, I really appre-ciated that my professors were involved inresearch. Their involvement in really bigideas, ideas way beyond our classroom,was thrilling.”

“But,” I said, “didn’t it bother you thatthere was little individual attention givento you from your professors?”

Jim did not even hesitate in his response.“I had the best GSIs ever. They wereincredibly smart and always available.”

The unsung heroes of teaching in ChemEare our graduate students. Their onemoment of recognition comes at our firstcolloquium of the academic year, duringwhich we present outstanding GSI awards.This ceremony is marked by public read-ings of excerpts from the written nomina-tions provided by our undergraduates andfaculty. These excerpts often tell of topicsmade clear, the un-confounding of difficultconcepts, and the time and care given tothe needs of individual students. It is notunusual to hear testimonies about howgood teaching changed lives.

And why should it not be so? Our graduatestudents have achieved every possiblemeasure of academic success in their under-graduate programs, as measured by grades,test scores, internships and research expe-riences. Reading the application files forour graduate program is humbling: oneoften finds that, in addition to the usualacademic successes, our applicants areaccomplished poets, writers, artists andmusicians. In recent years they haveshowed increasing commitment to causesthat bring science and engineering to chil-dren and youth, the disadvantaged and to non-governmental organizations.

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In short, our graduate students areremarkable.

They are well prepared for teaching. Allfirst-time GSIs attend a day-long teachingtraining session sponsored by the campus,and they are required to take a semester-long course in how to teach engineering.During this course, they study theories oflearning and the crafting of teaching ses-sions while they undergo the scrutiny oftheir peers in mini-teaching sessions.

Everyone knows that physician trainingincludes an internship with experienceddoctors in a clinical setting. The GSI posi-tion is part of our analogy to the medicalinternship: having demonstrated under-standing of the course material, havingstudied and practiced the theory of teaching,the graduate students work closely withour faculty in a mentor relationship whenthey serve as GSIs for our courses.

I have tremendous respect and admirationfor our graduate students. They serve onthe front lines of teaching engineering:leading discussion sections, holding officehours and helping to interpret the resultsof lab experiments. Jim got it exactly right.Berkeley’s winning combination pairsvisionary faculty members with extraordi-nary emerging scholars who have the talentand time for hands-on teaching.

by jeffrey a. reimer

JEFFREY A. REIMERChair, Department of Chemical Engineering, Warren and Katharine SchlingerDistinguished Professor

The unsung heroesof teaching

The winners of the 2007-08 Berkeley Teaching Effectiveness Award pose with Graduate DivisionDean Joe Duggan. Winners include ChemE GSI Ladan Foose (front left, in green), and Chemistry GSINicholas Stephanopoulos (rear, third from left).

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f a c u l t y p r o f i l e

Ming Hammond was the final graduatestudent of retiring Berkeley chemistry professor Paul Bartlett. In 2005, after com-pleting her Ph.D., she gave away the labequipment, turned off the lights and lockedthe door behind her. She departed the BayArea for a postdoctoral position at YaleUniversity.

Four years later, her postdoc complete,Hammond returned to the College ofChemistry, walked into an empty lab, turnedon the lights and began ordering equipmentas the chemistry department’s newestassistant professor.

Born Ming Chen in 1978 in Taipei, Taiwan,Hammond came to the United States withher parents in 1984. After living for a fewyears near relatives in Baton Rouge, LA,the family settled in Owings Mills, MD.Hammond’s father still works nearby as acivil engineer for one firm and her motherworks as a CAD (computer aided design)technician in a competing civil engineeringfirm. “We learned to enjoy eating crawfishwhen we lived in Louisiana and blue crabsonce we moved to Maryland,” saysHammond.

In high school, Hammond enjoyed herbiology and chemistry classes, includingher AP chemistry class. Her experience wasunique. Many U.S. high schools have beenforced to abandon laboratory instructiondue to budget cuts. But Hammond’s highschool chemistry teacher had taught at thelocal community college, and he gave heraccess to the chemistry labs there. By thetime she was ready for college, Hammondhad caught the bug for lab work.

Hammond entered Caltech in Pasadena, CA,in 1996. She studied chemistry and beganher research career as an undergraduate inthe group of professor Barbara Imperiali.While at Caltech, Hammond was chosen to

be a member of the first class of BeckmanScholars, a national program funded by theArnold and Mabel Beckman Foundationdesigned to encourage undergraduateresearch. Hammond graduated with a B.S.in chemistry in 2000.

Hammond’s undergraduate research projectin the Imperiali group, “Exploring thestructure of the eukayotic enzyme oligosaccharyl transferase via a localizedcross-linking reaction,” was part of aresearch program to produce chemicalprobes and inhibitors to better understandprotein glycosylation, a series of enzymaticprocesses which links sugars to proteins.In particular, reactions that link sugars to nitrogen atoms in the amino acidasparagine are important in biology. TheseN-linked glycans have major roles in mostliving organisms.

Although her undergraduate chemistryresearch was blossoming, physics was a bittougher. In her first year, says Hammond,“I was in the section for the unfortunatefreshmen who entered Caltech withouthaving already taken calculus-based physics.

But I had a good TA, so I made it through.”

Even as an undergraduate, Hammond wasbeing drawn into UC Berkeley’s orbit. WhenImperiali, her undergraduate researchadvisor, moved to MIT in 1999, Hammondspent that summer in Cambridge, MA, finishing her Beckman Scholars researchproject. On a particularly fateful day, mem-bers of the Imperiali group drove to a clambake at the summer home of another MITprofessor, JoAnne Stubbe.

Ming Hammond returns to theDepartment of Chemistry

A L A B O F H E R O W N

The Department of Chemistry's newest assistant professor, Ming Hammond, unpacks equipment as she sets upher lab in Lewis Hall. Hammond earned her chemistry Ph.D. at Berkeley with Paul Bartlett and returns to thedepartment after completing her postdoc at Yale University.



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“Inhibitors for protein-protein interactionshave potential as new medications, but sofar they remain elusive targets.”

Says Bartlett, “Ming Hammond was thefinal student to study for a Ph.D. in mygroup—number 63. The phrase that leapsimmediately to mind when asked for acharacterization of her is, ‘They save the bestfor last.’ Even as a student she demonstratedan amazing facility in synthetic chemistry,biochemical analysis, and computation—whatever it took to address the problem athand.”

According to Hammond, “Becoming aone-person research group had someadvantages. I sat in on the Ellman andFrancis group meetings, and I interacted alot with the other research groups on myfloor, especially the Bertozzi group.Carolyn Bertozzi ended up being my thesiscommittee chair.”

As a postdoctoral fellow at Yale, working inthe lab of biochemist Ronald Breaker,Hammond helped analyze a critical RNAmolecule that functions as a Boolean logicgate to control the expression of a metabolicgene in bacteria.

“People used to think that the genome waslike a data tape,” says Hammond. “Thedata were transcribed from DNA to messen-ger RNA and fed to ribosomes to produce

new proteins. Now we real-ize that the genome is more like acomputer program that controls how

genetic information is expressed.Some really interesting and sophisticatedcontrols of the genomic program are

enacted at the RNA level.”

For example, Hammond is interested insplicing regulation, or the way that introns(the non-coding segments of RNA) areremoved, while exons (the segments thatcode for proteins) are spliced together. “Ifsplicing is misregulated, the result can beerrors in the way proteins are built, andthat may lead to disease,” she says.

Says Hammond’s mentor Bartlett, “Ming’stour of duty as a postdoc outside Berkeleyenabled her to develop an even broader setof skills in molecular biology. I am enthu-siastic that she is back here, because ourcross-disciplinary outlook at Berkeley is agreat match for the type of research programthat she wants to pursue. I have no doubtthat her work will bring exciting and unex-pected results and be a terrific asset to thestudents here.”

As a Berkeley chemistry professor,Hammond foresees continuing her workon RNA gene control elements, with afocus on how these elements work in plants.“We are trying to understand the chemicalinteractions that drive RNA-based generegulation, with an eye toward applyingthat knowledge to the discovery of ‘naturalinteractors’ and to the design of ‘artificialinteractors’ with improved functional prop-erties. Our research questions require usto bring to bear tools from the fields ofmolecular biology, synthetic chemistry andbioinformatics.”

Hammond imagines her lab as “a place fordiscoverers and tinkerers, with an emphasison computational discovery and experimentalvalidation. I am very happy to be here,” shecontinues. “It’s already beginning to feellike home again.”

Stubbe is a former member of the Collegeof Chemistry advisory board who earnedher Ph.D. at Berkeley in 1971 and recentlywon the 2009 National Medal of Science.Hammond carpooled with Michelle Chang,an MIT grad student who in 2007 joined theBerkeley chemistry faculty. Chang marriedone of Hammond’s teaching assistants atCaltech, Chris Chang, who is now aBerkeley chemistry associate professor.

Five days after graduating from Caltech,Hammond married her college sweetheart,Mark Hammond, who had also graduatedfrom Caltech with a B.S. in 2000. Hisdegree was in engineering and applied sci-ence, and he works as a software engineer.

Ming Hammond joined Bartlett’s researchgroup at UC Berkeley in the fall of 2000.The group emphasized the application oforganic synthesis to biological problems, witha focus on the synthesis and study of enzymeinhibitors and metabolic intermediates.

For her dissertation, “Development andevaluation of beta-strand peptide mimics asinhibitors of protein-protein interactions,”Hammond worked in collaboration withBaruch Harris and Wendell Lim of UCSF.She earned her Ph.D. in bioorganicchemistry in 2005. “Protein-protein inter-actions play a key role in virtually everyprocess of living systems,” says Hammond.

d

Left: Arabidopsis seedlings growing ona solid media.

Above: An X-ray crystal structure of theRNA-based riboswitch that specificallybinds S-adenosylmethionine (SAM).

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INGHAMMOND



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n e w w o r l d sfor

berkeley chemists enhance the biomedical potential of NUCL EAR MAGNET I C R E SONANCE

P I N E S / W E M M E R

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Some technologies have so many practical applications and have become so wide-spread that we tend to forget they haven’t been with us all that long. Laptops, cell phones andthe Internet are good examples.

For many scientists, another example is nuclear magnetic resonance spectroscopy. NMR is basedon a characteristic of neutrons and protons called spin. It was well into the 20th centurybefore scientists who explored the strange new world of quantum mechanics began to ponderthe implications of spin.

It wasn’t until after WWII that simple NMR spectroscopy became possible, helped along bywartime developments in radar and other radio frequency applications. In the 1970s NMRtechniques were perfected to study solids. The application of NMR to proteins and othercomplicated biological molecules did not become routine until the 1980s.

Today we take for granted NMR techniques that have become indispensable for chemists,chemical engineers, materials scientists and biologists. Yet these techniques are roughly thesame age as the Berkeley grad students and postdocs who are using them.

Despite its roots in quantum mechanics, NMR has become a bread-and-butter tool that ispractical, reliable and mathematically tractable. Visiting a modern NMR facility is somethinglike watching an Olympic figure skating competition. It all seems so easy that we overlook theyears of hard work and practice that went into its perfection.

Some of that hard work has taken place in Berkeley’s College of Chemistry, in the researchgroups of chemistry professors Alex Pines and David Wemmer. Pines came to Berkeley in1973 and quickly became one of the world’s most creative leaders in the field of solid stateNMR. Wemmer was Pines’s second graduate student, and he returned to Berkeley and joinedthe faculty in 1985 as an expert in using NMR to decipher the complex structure of proteins.

About 10 years ago, the two colleagues began to work together to use the inert gas xenon toincrease signal strength in NMR and extend its usefulness in the realm of medical imaging.Pines and Wemmer are developing new techniques that someday may become as valuable androutine as NMR is today.

by michael barnes


Fertile soils and gentle rains do not develop the character of wine.Nor does a carefree youth necessarily develop the character of a scien-tist. Difficult growing conditions can allow good scientists, like goodwines, to deepen their character and continue to develop subtletiesfor many decades.

For both wine and science, 1945 was a vintage year. In theBordeaux region of France, frost, drought, heat and the hardships ofWWII led to a small harvest, but one that would produce exceptionalwines. In the same year, Felix Bloch at Stanford and Edward M. Purcellat Harvard independently developed the basic techniques of nuclearmagnetic resonance, a feat for which they would share the NobelPrize in Physics in 1952.

1945 was notable for another reason. In that year Berkeleychemistry professor Alex Pines, who would become a seminal figurein the development of NMR, was born in Tel Aviv. His parents hadmet in Egypt during WWII, where they both fought with the BritishArmy against the Germans in North Africa.

Pines’s father Michael, born in Warsaw, had fled his home inthe Baltic city of Vilnius as the Nazis rose to power in the 1930s. Hesettled in Southern Rhodesia, a British colony in Africa, and servedin WWII as part of the Rhodesian Brigade. Pines’s mother Neimalived in Palestine, where she joined the British Women’s AuxiliaryAir Force.

When Pines was four months old, his family returned toSouthern Rhodesia. Pines was raised in the city of Bulawayo, located20 degrees below the equator. It is the second largest city inZimbabwe, the name taken by the former colony when it achieved fullindependence in 1980. Bulawayo sits on a high rolling plain or veldat an altitude of 4,500 feet, giving it a moderate sub-tropical climate.

“My father started a produce store with his brother Simon thatis still in business today,” says Pines. “I remember the huge Africanavocados at the store, so big you could eat them with a tablespoon.I had devoted parents, three younger brothers and a circle of friendsfrom school.” Pines played chess and practiced the piano, excellingat both in national competitions. Although the location was unusual,in some ways he had a typical 1950s suburban childhood.

What made the household unique were the intellectual talentsof Pines’s parents, many of which were passed on to their four sons.“My father had pursued law and mathematics but was excludedfrom further study by anti-Semitic restrictions,” says Pines. “He wasa brilliant mathematician and chess player—for many decades hewas the national champion of the Federation of Rhodesia andNyasaland.” His chess mentors included Akiba Rubinstein, one ofthe world’s best players in the early decades of the 20th century.Rubinstein believed that had Pines’s father been able to stay inEurope, he could have been a great Grandmaster.

Says Pines, “My father was an intimidating presence at thechessboard—chain-smoking, staring with a piercing gaze.Although I am quite a good chess player myself, and I was theunder-21 champion at our local club, I was never able to beat him.Not once.”

Pines’s mother was a talented musician who sang, played thepiano and gave concerts in Bulawayo. She made the Pines home acenter of classical music performances. From her, Pines inheritedhis musical abilities. He was a gifted pianist as a child who audi-tioned for London’s Trinity College at age 15.

Bulawayo was a temporary home for an eclectic group of peoplewho were escaping the devastation of WWII and the dismantling ofGreat Britain’s colonial empire. Among their circle of friends thePines family counted the author Doris Lessing, who won the NobelPrize for Literature in 2007. Best-selling Scottish author AlexanderMcCall Smith, creator of the The No. 1 Ladies’ Detective Agency novels,was born in Bulawayo in 1948. Chess world champion Max Euwevisited Bulawayo, stayed at the Pines home, and played chess withhis host and other local masters.

Southern Rhodesia’s geographical isolation did not protectPines from the epidemic of polio that swept across the globe duringthe 1950s. The Salk vaccine had just become available, and Pineshad received two of the four shots when he contracted polio at age11. As Pines recollected in a 1999 interview, “I was disabled forquite a while and spent many months in a convent isolation ward,subsequently recovering almost completely. I recall the isolation


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A very good year A L E X P IN E S on wine, chess and chemistry


C ch fro to ch m Is pa


f e a t u r e

and uncertainty as quite traumatic. Only the love and support of myfamily made it at all bearable.”

It was an important observation for a young man who wouldbe torn between his mathematical and musical talents as he soughthis path in life. It was not math or music, but scientific research thathad produced the vaccine that had saved him. Yet science per se hadnot been enough—the human connection mattered, too. Later in hislife, Pines’s devotion to both science and the human connection—his regard for both research and teaching—would become a hallmarkof his career.

By age 15, Pines was growing restless. The world of Europeansin Southern Rhodesia was a small one. While other former coloniesin Africa were granted independence, Southern Rhodesia remaineda segregated state dominated by a white minority government. Overtime, the country would become more like South Africa, its neighborto the south. As Pines matured, life in a segregated society weighedmore heavily on him.

In 1961, at an age when most young people are settling intohigh school and dreaming of learning to drive a car, Pines left home,enrolling in an agricultural high school in Israel. “My family didn’thave enough money to send me to a conventional boarding school,”he says, “so I got up at 4:00 a.m. to milk cows and do other farm


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labor in exchange for room and board. Fortunately, I have a good earfor languages, because I arrived not knowing any Hebrew—Englishwas my native language.”

The school lacked instruction in higher math, physics andchemistry. Pines studied these subjects on his own and passed anexternal matriculation exam with an outside examiner sent from TelAviv. His test results allowed him to enroll in the Hebrew Universityof Jerusalem. But the multi-talented student still wasn’t sure what tostudy—law, math, science? The answer came in the form of a book,Linus Pauling’s classic, The Nature of the Chemical Bond, first pub-lished in 1939.

“Pauling’s book was a profound influence,” says Pines, “literallythe catalyst that allowed me to see how chemistry brought together therigor of mathematics, the beauty of music, the prospect of scientificprogress. After reading Pauling, I knew I wanted to do chemistry.”

Pines left Israel for a new adventure in a new country—a Ph.D.program at MIT in Cambridge, MA. Ironically enough, among allhis choices, only UC Berkeley’s College of Chemistry had notaccepted him.

At MIT, it didn’t take long for Pines to find his way to the lab ofJohn Waugh. Pines still recalls their first meeting. “When I toldWaugh I was interested in joining his group, Waugh, who was also

Clockwise from above: Alex Pines sets up a classicchess opening in his Stanley Hall office. A 1945 Bordeauxfrom Chateau Calon-Ségur, the bottle of wine presentedto Pines on his 60th birthday. Pines playing piano in hischildhood home of Bulawayo, Southern Rhodesia, andmilking a cow as an agricultural high school student inIsrael. Pines’s father Michael at the chessboard in apainting by artist Udi Peled.

Time reversal and violation of the spin-temperature hypothesis

Cross polarization and proton-enhanced NMR of dilute spins in solids

NMR studies of molecular struc-ture and dynamics of liquid crystals

Multiple-quantum spectroscopyand selective high n-quantum excitation

Berry’s phase and gauge kinemat-ics in magnetic resonance

Iterative quantum control of spins

Zero-field NMR and MRI by magnetic field cycling

SQUID detection of NMR and MRI at ultralow magnetic fields

Amplification of magnetic resonance with a laser magneto -meter and remote detection

Laser polarization and develop-ment of a xenon-based biosensor

Imaging of heterogeneous catalysiswith enhancement by parahydrogen

Microfluidics and NMR/MRI on a chip

P INES ’ S GREATEST H I TS


associated with the MIT Research Electronics Lab, handed me a circuitboard and instructed me to find a postdoc to help build a singlesideband amplifier circuit. So that’s what I did.”

“At that time,” says Pines, “Waugh’s lab was the center of theworld of high-resolution NMR. He was doing spectacular work onsolid state NMR, just as the related techniques of magnetic resonanceimaging (MRI) were being developed. For a budding scientist, itwas an incredibly exciting place to be.”

In the words of National Institutes of Health NMR scientist(and Pines lab alumnus) Robert Tycko, “Around that time, Waugh’sgroup included Ulrich Haeberlen, Michael Mehring, Bob Griffinand others who went on to become world leaders in various areas ofmagnetic resonance. But even in that illustrious group, Alex Pines’sbrilliance, creativity, and strength of personality stood out.”

Waugh’s group was extending the use of NMR to solids. Thisled Pines to attempt to detect carbon-13, an isotope that should,under the right conditions, yield a precise NMR signal. Unlike theabundant isotope carbon-12 which is “spin silent,” or magneticallyinactive, the relatively rare carbon-13 (only about one percent of nat-urally occurring carbon) will produce an NMR signal.

Pines learned how to use a series of radio frequency pulses toalign or polarize the spin states of the protons in hydrogen and thentransfer this polarization to carbon-13, greatly amplifying its signal.Along with Waugh and fellow student Michael Gibby, Pines co-authored a paper on the technique that appeared in 1973 in theJournal of Chemical Physics. To date, the article has been cited 1,985times—one of the most highly cited papers in the scientific litera-ture on NMR.

“I was very fortunate to have worked with John Waugh,” saysPines. “He is a great scientist and a great person.” Pines completedhis Ph.D. at MIT in 1972 and came to UC Berkeley for a prestigiousMiller Fellowship with physicist and NMR pioneer Erwin Hahn.However, the College of Chemistry, not wanting to miss a secondchance to attract him, persuaded Pines to join its faculty instead,where he has been a professor ever since. “Thankfully, Erwin Hahntook the change of plans in stride, and he has continued to be amentor and colleague all these years,” says Pines.

Having traveled from Africa to the Middle East and then toNorth America, Pines found a home in Berkeley, and his careerquickly blossomed. Even though he lacked the experience of a post-doctoral appointment, he set up a working lab and earned tenure inthree years.

Says Pines, “Solid state NMR became a huge success, withmany talented practitioners.” Today, chemists, chemical engineersand materials scientists routinely use NMR hardware that incorpo-rates concepts first developed in Pines’s lab.

“After several years, the point came where I began to feel thatthe field had matured and was dominated by a new generation,including many of my former students who had become tenuredprofessors. I was waking up in the mornings without new ideas in

solid state NMR.” Never one to jump on a bandwagon, Pines recog-nized that even though he had participated in creating the solidstate NMR bandwagon, it was time for something new.

With the same restless spirit that had propelled Pines across theglobe earlier in his life, he set out to explore new areas in NMR. Successin this new journey would require both a profound understandingof the nature of NMR, and a creative vision of what innovative appli-cations were possible.

“The real beauty of NMR,” says Pines, “is that unlike otherspectroscopy techniques, with NMR you can see inside bits of matter,including living organisms, without interfering with their chemistry.And with NMR, the information comes directly from the moleculesthemselves. The disadvantage of NMR is its low sensitivity. NMRinterrogates molecules with relatively low-energy radio waves, andraising the signal intensity requires huge, powerful magnets.”

The Pines group set out to harness the strengths of NMR whileovercoming its weaknesses. “We are seeking the best of both worlds,”says Pines, “the fidelity and penetration of NMR with the sensitivityof optical spectroscopy techniques.”

Vikram Bajaj is a postdoc in the Pines lab. Like Pines, heearned his Ph.D. in chemistry at MIT. When asked why he chose towork with the Pines lab, he summarized its accomplishments thisway: “Alex has contributed significantly to at least three areas ofNMR. First, in the NMR of solids, he has developed some of thebasic tools by which structural and chemical information can beteased from the interactions experienced by spins in the solid state.Second, some of his most elegant work has probed the fundamentalquantum mechanics and quantum statistics of ensembles of nuclearspins, including methods for their coherent control. Finally, Alexhas helped developed many applications of NMR, including zero-fieldNMR, portable NMR, the use of hyperpolarization in chemistry,biology and medicine, and recently, the combination of MRI withmicrofluidics.”

In 1984, two of Pines’s mentors, John Waugh and ErwinHahn, won the Wolf Prize, an international award that in chemistryand physics is second only to the Nobel Prize in prestige. Seven yearslater, in 1991, it was Pines’s turn. He shared the Wolf Prize in chemistrywith Richard Ernst because, according to the award committee, he,“while still a graduate student, helped engineer in 1972 (togetherwith John Waugh) one of the most important revolutions in modernNMR.…His later works in Berkeley have continued to profoundlyinfluence modern NMR spectroscopy.”

In 2002, Pines was appointed a foreign member of the RoyalSociety, the United Kingdom’s equivalent of the U.S. NationalAcademy of Sciences. He won the Russell Varian Award in 2008,the highest award given by the European NMR research communityto one of its own. Pines cherishes most these two awards, alongwith the Wolf Prize and honorary doctorates from the universitiesof Paris and Rome.


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In 2005, Pines’s life and career were celebrated at a Symposiumof the 4th Alpine Conference on Solid State NMR in Chamonix,France, held in honor of his 60th birthday. But there the award wasof a different nature. At the conference, a rare 1945 Bordeaux fromthe Château Calon-Ségur was uncorked. Like Pines’s research, ithad aged well over the years, developing complexities and subtletieswith time.

One of the many speakers at the conference was Berkeleyphysicist Erwin Hahn, Pines’s long-time mentor and friend. SaysHahn, “Whenever something new comes along, Alex sees theimplications before anyone else. He is a great thinker with a goodoverview of how to integrate new discoveries over a wide range ofapplications. He is a star attraction for students, especially postdocs.He has been a fountain of inspiration for the NMR community. I find him continually refreshing and always on the ball.”

Throughout his career, Pines has never lost sight of the humandimension of his scientific pursuits—mentoring and teaching hisstudents. In 1986, he won Berkeley’s highest teaching honor, the

Distinguished Teaching Award. He has spearheaded the developmentof the undergraduate chemistry curriculum, has regularly taughtundergraduate chemistry courses and is currently working on theeChem project, a series of videotaped chemistry demonstrations,lectures and quizzes that can be used for online instruction.

Pines credits his research group and collaborators for all of hisachievements. In 2000, he was the College of Chemistry’s commence-ment speaker. At the end of his speech, he summarized what he hadlearned from decades spent pursuing scientific knowledge. Hequoted Ta’anit, one of the central texts of the rabbinic literature:

Harbe lamad’ti mirabotai, umichaverai yoter mirabotai, umitalmidai yoter mikulam

“From my teachers have I been enlightened, more from my colleagues, but most have I learned from my pupils.”

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Right: College of Chemistry demonstration specialistLonnie Martin and Pines filming on the set of theeChem educational project.

Below: A diagram showing atoms of hyperpolarizedxenon as they are depolarized inside a cryptophanecage. The xenon acts as a contrast agent to enhancethe NMR signal.

“The real beauty of NMR is that unlike other spectroscopytechniques, with NMR you can see inside bits of matter,including living organisms, without interfering withtheir chemistry.”


It’s now more than a quarter-century since Berkeley chemistryprofessor Dave Wemmer first came to Berkeley. Although he joinedthe College of Chemistry faculty in 1985, he originally came to thecampus in 1974 and left four years later, the second student of AlexPines to complete his Ph.D.

The paths of Wemmer and Pines diverged for several years,both in terms of geography and research interests, but in the lastdecade, their paths have come together again, thanks to the collab-orative environment of the new Stanley Hall and to some usefulproperties of the inert gas xenon.

Born in 1951 in Sacramento, CA, Wemmer graduated fromhigh school in 1969 and attended Sacramento City College in hisfreshman and sophomore years. Like many of California’s collegestudents today, he transferred from community college to theUniversity of California after two years, graduating from the Daviscampus in 1973.

“When I was at Sacramento City College,” says Wemmer, “Ireally enjoyed chemistry and math, and I transferred to Davis as amath major. But I discovered there is a huge difference betweenlower and upper division math. Lower division math is more prac-tical, about solving problems. Upper division math is more abstract,and I found myself less drawn to that type of mathematics.Meanwhile, I had been enjoying my chemistry classes, so I addedchemistry as a major and graduated with a double major in mathand chem.”

Wemmer started graduate school in chemistry at UC Berkeleyin January 1974. He had worked with NMR as an undergraduate,and when he met Pines, something clicked. Wemmer’s Ph.D. thesis,“Some double resonance and multiple quantum NMR studies insolids,” was part of the growing literature on the application ofNMR to solids, a topic pioneered by the Pines group. There was nosign yet of the pending revolution in NMR techniques that wouldtake Wemmer in the direction of studying biological molecules.

Although he filed his dissertation officially in 1979, Wemmerleft in 1978 for a postdoctoral appointment in Dortmund, Germany,with physicist Michael Mehring. “I had taken some German in highschool and college,” says Wemmer, “but for the first three months,it was tough to understand the people around me.” After a yearoverseas, Wemmer decided to jump back into the job market in the

United States. He landed a job at Stanford University as a staffmember in the solution NMR facility, where he helped researchersconduct studies in the emerging field of biological NMR.

“In grad school in the Pines lab,” says Wemmer, “we built ourown equipment, so I was strong in instrumentation. At Stanford, theyneeded help with hardware, but over time I became more interestedin the applications to biomolecules. I was in the right place at theright time. The field was starting to explode, due in part to the workof Swiss scientist Kurt Wüthrich.”

Wüthrich, who had been a postdoc at Berkeley with the college’sRobert Connick in 1965-67, spent two years at Bell Labs andreturned to Zurich, Switzerland, in 1969. There he worked out theprinciples of how to systematically apply NMR to complex proteinsand other biomolecules, and a new field was born. Wüthrich wonthe 2002 Nobel Prize in Chemistry for his research.

Wemmer left Stanford in 1983 for an academic appointment asan assistant professor of chemistry at the University of Washington,where he stayed for three years. In 1985, with support fromBerkeley biophysical chemists John Hearst and Ignacio Tinoco,Wemmer joined the College of Chemistry faculty.

“John and Nacho liked the idea of having an expert in the bio-logical applications of NMR on the faculty,” says Wemmer. “If Istayed at UW, I was pretty sure I would get tenure, but it was muchless of a sure thing at Berkeley. For me the difference between thetwo schools was clear-cut, and I wanted to be in the best place to doresearch. So I took my chances and returned to Berkeley.”

As NMR began to be applied to determine the structure of evermore complex proteins, techniques were needed to expand beyondthe typical one-dimensional spectra of that era. In one-dimensionalNMR, the output is a line graph with characteristic peaks at certainfrequencies that help determine the composition of the sample.“That works for relatively simple compounds,” says Wemmer, “butnot for large complicated biological molecules like proteins andDNA. For these biomolecules, we absolutely need the higher reso-lution and higher information from two-dimensional NMR.”

Two-dimensional NMR shares similarities with topologicalmaps. From the Bay Area, you can scan the horizon north-to-southand detect a few prominent peaks on the horizon—Mt. Tamalpais,Mt. Diablo and the ridgeline of the coastal hills. But as you head


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Rolling the diceDAV ID WEMMER on the rise of biological nmr



east, you are initially confronted by the solid gray band of theSierras, where the peaks seem so tightly compressed together thatyou can’t tell one from another.

Yet when you fly over the Sierras in an airplane, you can makeout how the peaks are spread out along both the north-south andeast-west directions. A topological map shows the locations of allthe peaks in two dimensions and indicates the intensity of the peaks(their altitude), as well.

Says Wemmer, “Two-dimensional NMR creates a topo map ofa protein’s characteristics, allowing you to discriminate features inmuch greater detail. A protein has a structure with a main trunk orbackbone, and many branches. NMR tells you about the environ-ment of the chemical bonds in proteins, and where nuclei are posi-tioned along a branch.

“Using a technique called Nuclear Overhauser Effect you canalso measure how far nuclei are apart in physical distance, even if

they are not on the same branch. If a protein is folded, the nuclei ofamino acids that are far apart along a branch can lie very close toeach other in space, and this distance can be determined by usingNuclear Overhauser Effect Spectroscopy, or NOESY.”

Today computers can take the results from multi-dimensionalNMR and NOESY and reconstruct the structure of very complexproteins of more than 50 kiloDaltons (which contain 50,000 gramsper mole, or about 500 amino acids). The analysis of these complexbiomolecules requires NMR spectrometers like those available inthe Stanley Hall NMR facility. The largest of these superconductingNMR magnets uses over 60 miles of wire, is cooled to two degreesabove absolute zero through the evaporative cooling of liquid helium,and produces a magnetic field of 21 Tesla, or 400,000 times as strongas that of the planet Earth.

Wemmer works closely with Jeff Pelton, the manager of theNMR facility. Pelton earned his Ph.D. with Wemmer and began

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Above: Chemistry professor David Wemmer at the con-trols in the Stanley Hall NMR facility. Behind him is thelargest NMR magnet on campus, which is cooled toapproximately two degrees above absolute zero andcapable of producing a magnetic field of 21 Tesla,400,000 times more powerful than that of planet Earth.

Right: Wemmer in the early 1970s as a graduate stu-dent in the research group of Alex Pines.

Above: The Wemmer research group usesNMR , X-ray crystallography and other bio -physical techniques to detail the conformationof complex proteins.

Below: A xenon atom trapped in a cryptophanecage has been attached to a linker that makes itwater-soluble. Various ligands can be fine-tunedto bind the caged xenon to specific proteins,including unique cancer proteins, to allowtumors to be detected using NMR.

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managing the facility after a postdoc at the National Institutes ofHealth and a position as a staff scientist at Lawrence BerkeleyNational Laboratory. Wemmer is also a faculty scientist at LBNL.

Says Wemmer, “Although it is an essential tool, my group’sresearch is not confined to NMR. We do structural biology usingNMR in conjunction with other techniques like X-ray crystallographyand mass spectroscopy. We also collaborate with other groups thatwould like to apply NMR to their structural biology problems.”

Over the past few years most of the group’s studies of proteinshave focused on those involved in regulation of genetic expression.Several of these proteins are transcription factors, which are struc-tures that recognize DNA and help assemble the other proteinsnecessary for transcription. During transcription, genetic informationfrom DNA is transferred to messenger RNA to begin the process ofcreating new proteins.

Among these transcription factors are response regulators thatinclude a DNA-binding domain. The Wemmer group studies thestructure and mechanisms of these response regulators from theextreme thermophilic bacteria Aquifex aeolicus using a combinationof NMR spectroscopy, X-ray crystallography and other biophysicaltechniques. Says Wemmer, “Aquifex aeolicus naturally occurs inwater from geothermal pools and is happy to live at 85 degreesCelsius. Its proteins are very robust at room temperature, and thatmakes it a good candidate to study.”

In particular, the Wemmer group studies the structure andfunction of a set of proteins that regulate the start of transcription,called sigma54 activators. The researchers investigate the structureof individual domains, the structural requirements for function andDNA-binding activity. “In bacteria,” says Wemmer, “these proteinsbind near the beginning of gene sequences in the DNA and pullthe ‘starter cord’ on RNA polymerase that activates transcription,creating messenger RNA. But how do these proteins bind to DNA,and what signals them to pull the starter cord? That’s what we aretrying to understand.”

Another area of interest for the Wemmer lab is metabolomics,the systematic analysis of products of cellular reactions. “Basically,”says Wemmer, “you feed sugar to bacteria and trace where it goes.There are lots of metabolic pathways—how much goes througheach one? There is tremendous interest in harnessing metabolicpathways in bacteria by using synthetic biology techniques to producenew drug candidates and biofuels. Yet we really don’t understandthe metabolic pathways as well as we could.”

Wemmer cites as an example the work of Sydney Kustu, aBerkeley professor of plant and microbial biology, who recentlydiscovered a previously unknown metabolic pathway in E. coli thatallows it to consume its own DNA nucleotides when starved fornitrogen. “That’s like burning your house for warmth if you arefreezing,” says Wemmer, “but E. coli has the pathway to do it. Thisis the most extensively studied organism in biology, and its genomehas been fully sequenced for years. Yet no one saw this coming. We

are working with the Kustu group to identify the chemical productscreated by this pathway.”

“A major advantage of NMR-based techniques in biology andmedicine is that they do not require radioactive materials,” saysWemmer. One of the most famous studies of plant metabolism wasthe work of Berkeley chemist Melvin Calvin, who won the NobelPrize in Chemistry in 1961 for his photosynthesis research. LBNLhad developed techniques to produce sufficient quantities ofradioactive carbon-14 for research, and Calvin used the isotope totrace how plants take up carbon dioxide to produce carbohydrates.

“Today,” says Wemmer, “we could do the same experimentwithout relying on radioactivity. The standard form of carbon,carbon-12, is not radioactive. It is also ‘spin-silent,’ which meansthat it is magnetically inactive and can’t be detected using NMRtechniques. However, carbon-13, which is not radioactive, can bedetected using NMR technology. We could feed plants carbon dioxideenriched with carbon-13 and recreate Calvin’s Nobel Prize-winningexperiments with NMR, using no radioactivity at all.”

Because NMR interrogates the spin-states of nuclei, a processthat doesn’t affect the chemistry, it can be used as a non-invasivebiosensor to monitor biological processes within the body. Thepotential of NMR biosensors is the topic that brought together theresearch of Wemmer and that of Alex Pines, his former researchdirector.

“About 10 years ago,” says Wemmer, “Alex Pines and I werediscussing hyperpolarized xenon, which then was being used forNMR analysis of surfaces. We wondered if hyperpolarized xenonwould leave enough of a trace of ‘spin flips’ that we could use it todetect binding pockets in proteins.”

Pines and Wemmer needed an adaptor molecule to makexenon interact with targets of interest, and so they consulted withchemistry colleague Peter Schultz (now a professor at the ScrippsResearch Institute near San Diego, CA). “Although he warned us itwould take a lot of work,” says Wemmer, “Schultz had a postdocstart on creating an artificial binding pocket for xenon. The effortwas a success, and the Schultz group created a cryptophane cage,capable of trapping a single xenon molecule, with an attached link-ing arm that made the cage water-soluble.”

Since then, Wemmer and Pines have worked with the researchgroups of colleagues Jean Fréchet, and most recently, Matt Francis,to create ligands that will bind the xenon cages to specific targets inthe body, including certain proteins that are unique to cancer cells.

“Xenon has lots of advantages,” says Wemmer. “There is nonaturally-occurring xenon in the body to interfere with the biosensor.The hyperpolarization creates a very strong signal, and unlike X-raybased techniques like CAT scans, a doctor could monitor thesebiosensors frequently without any risk to the patient. Since it is anoble gas, xenon is chemically inert inside the body, although forreasons not well understood, its binds to nerve receptors, giving itmild anesthetic properties.”


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One likely application for the xenon biosensors will be to mon-itor the effectiveness of cancer chemotherapy. Continues Wemmer,“Cancer is not just one disease—even lung cancer can be caused byseveral different cancers, each of which will respond to treatmentdifferently. A xenon biosensor could bind to particular types ofproteins secreted by certain cancer cells, and the sensors could bemonitored over the course of several days or weeks to detect theshrinkage of even very small tumors. We continue to work with thePines group to develop the xenon biosensors, and we hope to startexperiments in living cells soon.”

The Wemmer group’s interdisciplinary approach to itsresearch is no accident. Interaction between researchers from manydifferent Berkeley departments and other UC campuses was part ofthe design of the California Institute for Quantitative Biosciences (QB3),housed in Stanley Hall. Says Wemmer, “QB3 has been a great success.I can interact with chemists, biochemists and biophysicists withoutleaving the building. Plus, the Pines group is just downstairs.”

John Kuriyan, a QB3 colleague in the chemistry department, istaking advantage of Wemmer’s expertise. Kuriyan is analyzing thestructural basis for resistance to imatinib, an important anti-cancerchemotherapy agent. According to his website, “The only way toobtain definitive insights into these conformational transitions is likelyto be through the use of nuclear magnetic resonance, and this is a

major goal of our future work in collaboration with David Wemmer.”Says Kuriyan, “Dave Wemmer has made me appreciate how

useful NMR is for determining protein structure. It helps that hereat QB3, we have one of the nation’s best NMR facilities, and managerJeff Pelton has been invaluable. I’m looking forward to continuingour work with Pelton and the Wemmer group.”

In 1985, Wemmer had needed to make a decision—stick witha sure thing, or roll the dice and try for a higher, but riskier payoff.Wemmer rolled the dice.

It was a good bet. At Berkeley, the biological applications ofNMR and Wemmer’s career have both flourished, due in part to thespecialized facilities Wemmer helped create.

“Back in 1985, I made the right call when I decided to comeback to Berkeley. The combined resources of the college, LBNL andQB3 are hard to beat. And Stanley Hall has become a special placeon a special campus.”

Perhaps Wemmer’s choice is not so surprising. Scientists areby nature explorers and risk-takers. The world that Wemmerexplores, the intricate structures of biological molecules like DNAand complex proteins, is still a world full of mysteries. Solving thosemysteries, and creating a better understanding of that world, willcontinue to yield tremendous benefits for humanity.

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The Wemmer and Pines research groups have developed a technique for using hyperpolar-ized xenon gas as an NMR contrast agent. Chemical exchange saturation transfer (CEST)starts with xenon gas that has had its spin-states aligned (hyperpolarized). When trappedin a cryptophane cage and subjected to a burst of radio frequency energy, the hyperpolar-ized state is reversed. Eventually, a cloud of depolarized xenon builds up around the cageand yields a shifted resonant frequency when interrogated with NMR. If the cyptophanecage is linked to a protein that is unique to cancer or another disease, NMR techniquescan be used as very precise diagnostic tools.

“A major advantage of NMR-based techniques in biology and medicine is that they do not require radioactive materials.”



18

The NASA bureaucrats weren’t quite surewhat to make of this young rag-tag group.The clashes between JPL’s managers andPimentel were relentless. In early 1968,Pimentel sent a letter to a NASA adminis-trator. Never one to mince words, Pimentelfiercely protected the independence of hisyoung team:

“We are again encountering the abrasiverecurrence of the perennial and understand-able difficulty JPL has in accommodating itsrather rigid management procedures to anindividualistic, independent and highly com-petent University research group. They wouldbe much more comfortable with a more submissive organization producing an instru-ment of far less capability and correspond-ingly fewer new problems to be solved.”

At the top, Pimentel and the JPL managerslearned to work together. In the trenches, theIRS team found the JPL engineers and tech-nicians far more enthusiastic and willing tohelp, and the IRS team relied on theirexpertise.

Mariner 6 encountered Mars on July 31, 1969,while Mariner 7 reached the planet fivedays later on August 5. Aboard Mariner 6,the cryostat unfortunately failed to cool thelong-wavelength sensor, making it inoperable,although the short-wavelength sensor wasunaffected. But on Mariner 7, both detectorsworked flawlessly. The elation of the teamwhen the Mariner 7 IRS began cooling wasrecorded in a NASA documentary (avail-able at marinermars69.weebly.com/nasa-videos.html).

The IRS team confirmed the presence ofwater ice in the southern polar ice cap, alongwith frozen CO2. They also detected higherconcentrations of frozen water at the edge ofthe cap, but could not confirm the presenceof ammonia, methane or other organiccompounds.

The Mariner IRS data set remains unique,not only because of the quality of the instru-ments, but because the team did theirhomework—extensive, well-documentedtests with an identical instrument in the lab,calibrated with mineral and gas samplessimilar to those likely to be found on Mars,tested in a simulated Martian environment.

At the time, however, the procedures forarchiving the data tapes had not beenworked out. Although some informationwas transferred to microfiche, during thefollowing years the NASA funding driedup, members of the Mariner IRS groupdisbanded and moved on to other careers,and the data tapes were relegated to a stor-age locker and forgotten.

The story of the Mariner missions mighthave ended there, except for the arrival of afinal and unexpected member of the MarinerIRS team, a kindred spirit whom the othershad never met. That’s because at the timeshe was just entering elementary school.

Laurel Kirkland is not the sort of personwho gives up easily. Born in the Houston,TX, area in 1962, Kirkland joined the U.S.Coast Guard after completing high school.She worked first as a diesel mechanic andlater as an electrician.

After her tour of duty was completed, sheworked in shipyards in Virginia beforereturning to Houston, where she enrolledat Rice University and earned a degree inplanetary geophysics in 1994. As a Ph.D.in geophysics at Rice, she began her thesisresearch on the mineral composition of thesurface of Mars.

“One day—it must have been in 1995,” saysKirkland, “I was looking through somearticles, and I saw a graph from an infraredspectrometer of the Martian surface. I couldtell it was a very good instrument from the

Pulling the veil from MarsM A R I N E R M I S S I O N

Forty years ago, Berkeley’s Mariner 6/7 IRS group sent a uniqueinfrared spectrometer to Mars

Clock prepa (l. to Don R Ken H the M officeLaure tapes availa In a r Pime proof Maps Marin the so prese

In the early 1960s, Berkeley chemistry pro-fessor George Pimentel forged a reputationas a leader in the area of infrared spectro -scopy. His research group included KennethHerr, a talented instrumentalist who wasdesigning a new interference-filter spectro -meter. Together they won a grant from NASAto develop a prototype of an instrumentthat was accepted in 1966 for the MarinerMars missions.

NASA balked at a grad student being des-ignated a principal co-investigator. Herrhunkered down and wrote his thesis in sixweeks, and he became the director of theproject’s day-to-day activities. The Marinerinfrared spectrometer (IRS) was designed bya team hand-picked by Pimentel and Herr.The team built the instruments with helpfrom the Berkeley Space Sciences Laboratory(SSL), the NASA Jet Propulsion Laboratory(JPL) in Pasadena, CA, and the college shops.

The most controversial aspect of the MarinerIRS would prove to be its active coolingsystem. Pimentel and Herr wanted to recordthe long-wavelength infrared data with thehighest signal-to-noise ratio possible. Thatrequired a detector that would only functionat extremely low temperatures, far lowerthan the spectrometer’s other infrared sensor, a short-wavelength detector thatwas cooled by radiating heat into space.

The design of the cooling system fell to LesHughes, an undergrad physics major whohad been making ends meet by working ata drug store while building oscilloscopes athome. Hughes saw a job posting at the UCBerkeley employment office and contactedHerr and Pimentel, who agreed that talentand enthusiasm were more important thanformal training and experience. Hughesdesigned a cryostat system that used pressur-ized nitrogen and hydrogen to cool thelong-wavelength detector to 22 degreesabove absolute zero.



19decoded. The tapes were old and brittle, butshe found a solution to that problem atTexaco, where she was interning. Likemany oil companies, Texaco occasionallyneeded to recover geological data fromfragile older tape. Texaco generously paidfor the IRS data to be handled by special-ists who used a low-speed, low-tensiontape drive to successfully read the tapes.

With the data transferred, Kirkland realizedshe faced yet another obstacle. “All we hadwere zeros and ones,” she says. “The tapeswere not in a standard format. Without thedetails of how the data were coded, it wouldbe almost impossible to reconstruct.”

By that time, Kirkland was in touch withHerr, project scientist Paul Forney andother former members of the IRS team.Don Stone, the IRS missions’ data techni-cian, was working with Herr at AerospaceCorporation in Los Angeles. Stone volun-teered to fly out to Houston, and Aerospaceagreed to pay his costs.

“All those years later, he still rememberedthe data format,” says Kirkland. “We were

sitting in the Rice library, using an old Unixwork station. Don had worked out how tointerpret the format and graph the results.As soon as the graphs popped up, I couldsee the CO2 spectral lines. Don’s memory,patience, and computer skills were amazing.”

Kirkland not only wrote her dissertation withthe IRS data, she helped complete partiallywritten articles with the group members,wrote new articles herself, and ensured thatthe data were properly archived for otherresearchers’ use.

Kirkland now works with Herr at AerospaceCorporation. Recently, the Mariner 6/7 IRSgroup gathered at the Berkeley SSL fortheir 40th anniversary reunion. Kirklandwas there, as she had been 10 years earlierat the 30th reunion. “I’m sorry I never gotto meet George Pimentel,” she says. “Hedied before I became interested in theMariner missions. In some ways we dothings fancier now, but the Mariner 6/7missions were the first to pull the veil fromMars—they were the ones that took usfrom not having a clue what was there to a pretty good idea what Mars is all about.”

precision of the graph—in the same wayyou can spot a good camera by the qualityof the photos it takes.”

The graph that Kirkland saw that day hadbeen generated with data from the 1969Mariner 6 and 7 missions to Mars. Excitedby the possibility of using the Mariner IRSdata for her thesis, Kirkland was stunnedwhen she learned that most of the IRS datafrom the missions were missing.

Like a detective in a mystery story, Kirklandset out to find the data. George Pimentelhad died in 1989, but Kirkland found animportant ally in Jeanne Pimentel, George’swidow, who had donated his papers to theBerkeley campus’s Bancroft Library.

In late 1996 Kirkland contacted JeannePimentel, and a few months later they foundthe missing data tapes in a dusty, darkbasement storage area of UC’s MarchantBuilding in Berkeley. The tapes, along withprototypes of the instrument, had been sit-ting in storerooms for over two decades.

Kirkland shipped several cases of tapes toHouston, where she set about having them

s p e c i a l f e a t u r e

Clockwise from above: The Mariner IRS teamprepared the instrument for its 1969 flight: (l. to r.) Wayne Morris, Harry Gee, Ken Herr,Don Renfro and Jim Shand. Ken Herr and George Pimentel discuss plans forthe Mariner mission in Pimentel’s Hildebrandoffice.Laurel Kirkland in 1997 with the Mariner datatapes. She restored the data and has made itavailable to other researchers. In a recent photo, Dean Richard Mathies, JeannePimentel and Les Hughes examine the college’sproof test model of the Mariner IRS. Maps of Mars reveal the scan paths for theMariner 6 and 7 missions. Mariner 7 scannedthe southern Martian ice cap, revealing the presence of water ice.



20

LBNL NUCLEAR SCIENCE DIVISION

JBEI

Don’t FRET overbroken polymersFluorescent proteins couldone day help identify micro-scopic cracks and damage inpolymer materials, allowingthem to be monitored to prevent failure in load-bearingapplications such as in aero-space and biomedical devices.ChemE professor DouglasClark and colleagues encasedtwo fluorescent proteinsinside two halves of a protec-tive protein shell and embed-ded them into a polymermatrix. How far the twohalves of the shell are pulledapart affects the fluorescence resonance energy transfer(FRET) of the two proteins.Monitoring the fluorescencecould indicate where thepolymer is being deformedor cracked.

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Superheavy element 114 confirmed: a stepping stone to the island of stabilityFor decades nuclear scientists have searched for an island of stability amongnotoriously short-lived artificial elements. Now researchers at the LawrenceBerkeley National Laboratory’s Nuclear Science Division (NSD) and UC

Berkeley have made a step forward in the quest by confirming the production ofthe superheavy element 114, 10 years after a group in Russia at the Joint Institute

for Nuclear Research in Dubna first claimed to have made it.

Professor of Chemistry Heino Nitsche, head of the Heavy Element Nuclear andRadiochemistry Group in NSD and Ken Gregorich, a senior staff scientist in NSD, led theteam that independently confirmed the production of the new element, which was firstpublished by the Dubna Gas Filled Recoil Separator group.Microbe metabolism

harnessed to produce fuelMicrobes such as the yeast we commonly usein baking bread and fermenting beer are nowbeing engineered to produce the next generationof biofuels. Jay Keasling, professor of chemicalengineering and CEO of the Joint BioEnergyInstitute (JBEI), is leading a team of scientistsin an effort to manipulate the chemistry withinbacteria so they will produce fuel from sugar.

At JBEI, one of three research centers set up by the Department of Energy for the researchand development of biofuels, Keasling is usingsynthetic biology techniques involving chemistry, genetic engineering and molecular biology. Foundational work being done at the Synthetic Biology Engineering ResearchCenter (SynBERC), where Keasling is director,will underpin the research at JBEI. SynBERC is funded by the National Science Foundation.



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Gene transcribing machine takes halting,backsliding trip along the DNAThe body’s nanomachines that read our genes don’t run as smoothly as previously thought, according to a new study by Berkeley researchersin the group of chemistry professor Carlos Bustamante (Ph.D. ’81,Biophysics; Postdoc ’82). When these nanoscale protein machinesencounter obstacles as they move along the DNA, they stall, often forminutes, and even backtrack as they transcribe DNA that is tightlywound to fit inside the cell’s nucleus. The Berkeley researchers devel-oped an optical tweezers assay to directly watch individual nanoscaleprotein machines as they move along single molecules of DNA. Themeasurements are reported in the July 31 issue of the journal Science.

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New images capture cell’s ribosomes at workChemistry professor Jamie Cate and co-workers have for the first time captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take ingenetic instructions and amino acids to churn out proteins.

Ribosomes, which number in the millions in a single human cell, have long been considered the “black boxes” in molecular biology. “We know what goes in and what comes out of ribosomes, but we’reonly beginning to learn about what is going on in between,” said Cate.

“Inside the ribosome, antibiotics and viruses are using chemistry toeither fight or promote disease,” said Cate, who conducted the workwith research specialist Wen Zhang and graduate student Jack Dunkle,both co-lead authors of the study, in his lab at UC Berkeley. “But whatsort of chemistry? The short answer is that we still have a lot to learn.Once we find out, that knowledge could lead to more effective antibi-otics, or new treatments against devastating diseases like hepatitis C.”

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Gold solution for enhancing nanocrystalelectrical conductanceIn a development that holds much promisefor the future of solar cells made fromnanocrystals, and the use of solar energy toproduce clean and renewable liquid trans-portation fuels, researchers at the LawrenceBerkeley National Laboratory (LBNL) havereported a technique by which the electricalconductivity of nanorod crystals of the semi-conductor cadmium-selenide was increased100,000 times.

“The key to our success is the fabrication ofgold electrical contacts on the ends of cadmium-selenide rods via direct solution phase-growthof the gold tips,” says Paul Alivisatos, Berkeleychemistry professor and the newly-appointeddirector of LBNL, who led this research.“Solution-grown contacts provide an intimate,abrupt nanocrystal-metal contact free of sur-factant, which means that, unlike previoustechniques for adding metal contacts, ourspreserves the intrinsic semiconductor characterof the starting nanocrystal.”

Chris Chang wins AstraZeneca Award Professor of Chemistry Chris Chang has won the2009 AstraZeneca Excellence in Chemistry Award.Chang was selected by a team of AstraZeneca seniorscientists, in consultation with world-leading aca-demic scientists. The award includes a $50,000unrestricted research grant intended to foster contin-ued growth and development of research programs.

BERKELEY CHEMISTRY

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Dear Alums,Once again, it has been a busy fall! The AlumniAssociation’s fall activitiesgot off to an early andenergetic start with theSenior Class dinner onSeptember 9. Now in its

second year, this event kicks off both thesenior year and the growing Senior ClassCampaign.

The college’s participation in HomecomingWeekend was a big success, including acontinental breakfast and an overflowingcrowd for the lecture by chemistry profes-sor Richmond Sarpong on October 3.

Our Free Radicals group (1964–79) com-bined their annual event with a CampaignKickoff on October 30. College lecturerMark Kubinec gave the group a sneak pre-view of a new online eChem curriculum.The Free Radicals have set an endowedprofessorship and renovations to theundergraduate labs as their campaign goals.

More than 150 friends, alums and facultymembers attended the AIChE reception inNashville, TN, on November 11, and weheld the Alumni of the G. N. Lewis Eraluncheon on November 19.

Please check the website (chemistry.berkeley. edu/alumni) for the latest news from youralumni association. We hope to see you soon.

Go Bears!

Berni J. Alder (M.S. ChemE) isamong nine eminent researchersto receive the 2009 National

Medal of Science, the highest honorbestowed by the United States governmenton scientists, engineers and inventors fortheir outstanding contributions to scienceand engineering. A retired physicist fromLawrence Livermore National Laboratory(LLNL), Alder is widely regarded as thefounder of molecular dynamics, a computersimulation used to study motions andinteractions of atoms over time. Whileworking on his Ph.D. at Caltech, he andcomputer designer Stan Frankel developeda computer technique, now known as theMonte Carlo method, for calculating resultsfrom random sampling. His subsequentwork at the newly-established LawrenceLivermore lab led to publication of his pioneering work on molecular dynamics.In 1963, Alder helped found the UC DavisDepartment of Applied Science.

Henry M. Neumann (Ph.D.Chem) retired this year from thefaculty of Georgia Institute of

Technology in Atlanta. He makes his homein Decatur.

Max J. Kalm (Ph.D. Chem) andhis wife, Lila, enjoy retirementat Bentley Village in Naples, FL,

where he serves on their resident council

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’48and sales and marketing committee. Healso writes articles to promote both BentleyVillage and Junior Achievement of SWFlorida and is a member of Bentley’s men’sgolf association. Before retirement heworked for Schering-Plough in New Jersey.

In July, Edwin T. Strom (M.S.Chem) was among the 162 fellows selected from the

American Chemical Society’s 154,000members to be named inaugural AmericanChemical Society Fellows, chosen for “trueexcellence in their contributions to thechemical enterprise coupled with distinctiveservice to ACS or to the broader world ofchemistry.” He was also elected Chair-Electof the American Chemical Society Divisionof the History of Chemistry. Strom serves asan adjunct professor at the University ofTexas, Arlington, where he teaches organicand polymer chemistry. He and his wife,Charlotte, make their home in Dallas.

Frederick M. Peterson (B.S.ChemE) is president of ProbeEconomics Inc in Hanover, NH,

providing clients with chemical industryplanning, forecasting and consulting services.

After 35 years in the engineering/construction industry withFluor and Jacobs, where he

started as a process engineer, Richard C.Delaney (B.S. ChemE) retired as an engi-neering group manager. He now enjoys “a life of golf and leisure” in Indio, CA.

JoAnne Stubbe (Ph.D. Chem)was awarded the prestigiousNational Medal of Science this

year for her work on enzymes involved inDNA replication and repair. A professor ofchemistry and biology at MIT, Stubbe waselected to the National Academy of Sciencesin 1992. She has served on the College ofChemistry Advisory Board and will be thecollege’s 2010 commencement speaker.

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—REBECCA ZUCKERMANPh.D.’00, Chem

Chair, Chemistry & Chemical EngineeringAlumni Association Steering Team

Free Radicals Alumni Event and Campaign Kickoff: (l.) Mark Wegner (Ph.D. ’77, Chem) chats with Tom(M.S. ’73, Chem E) and Marty De Jonghe in the remodeled Bixby Commons.(r.) Kirk Lao (B.S. ’09, ChemE) and Baljit Kaur (B.S. ’11, ChemE) enjoy the balmy weather and great foodat the 2nd annual senior class dinner.

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Sabrina G. Sobel (Ph.D. Chem)continues to serve as a full pro-fessor and chair of the chemistry

department at Hofstra University inHempstead, NY.

Last May, Daniel J. Sullivan(Postdoc Chem) took the positionof manager of the failure analysis

lab at ISE Labs in Fremont, CA, whichoffers analytical services, including X-ray,acoustic and optical microscopy, de-capsu-lation, and cross-sections. Early this year,he and his wife, Christie, welcomed adaughter, Cashel, to the family. He alsoruns a business called Earwig Enterprisesand has recently published a new cardgame, “Go Knights! Go Dragons!,” whichis on sale at game stores and at earwig.net.Another game still available from Earwigis, “Infection: A light-hearted and educa-tional game of human afflictions.”

In summer 2008, Jeffrey S.Kieft (Ph.D. Chem) was promoted to associate professor

with tenure at the University of ColoradoDenver School of Medicine. In October2008, he was named director of theirBiomolecular Structure Program, and thisSeptember, he began his appointment as aHoward Hughes Medical Institute EarlyCareer Scientist. He and his wife, Birgit,live in Denver.

A senior research scientist formicroelectronics technology atLord Corporation in Cary, NC,

Sara N. Paisner (Ph.D. Chem) was electedpresident of the International Microelectronicsand Packaging Society (IMAPS) CarolinasChapter in June 2009. Before joining LordCorp, she worked at GE’s Global ResearchCenter, focusing on developing new mate-rials for the electronics industry. At Lord,she leads projects to develop the company’snext generation of thermal interface gels,greases and adhesives for the microelec-tronics industry. She is also an activemember of the American Association for

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the Advancement of Science, the AmericanChemical Society and Iota Sigma Pi.

Since earning his Ph.D. in bio-engineering from the Universityof Pennsylvania in spring 2009,

Richard K. Tsai (B.S. ChemE) has beendoing postdoctoral research in Penn’sDepartment of Chemical and BiochemicalEngineering. He and his wife, Joy Lee,make their home in Philadelphia.

Having worked as a researchassociate in UCSF’s CellCulture Facility since last year,

Theresa N. Canavan (B.S. ChemBio) is veryexcited about being accepted to their Classof 2013 M.D. program.

Jesse Dashe (B.S. ChemBio) is in his secondyear of medical school at UC San Diego.

Michael E. Grass (Ph.D. Chem) starteddoing postdoctoral research in September2008 at Lawrence Berkeley National lab’sAdvanced Light Source division.

Kihoon Kim (B.S. '03 Chem; Ph.D)remained at Berkeley after graduation topursue a Ph.D. in comparative biochem-istry, conducting research in the field ofinfectious diseases and antiviral therapy.

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He then accepted a position as senior con-sultant with Entrue Consulting Partners inSeoul, South Korea, where he is currentlyworking in areas of corporate finance andstrategic transactions of major corpora-tions, both inside and outside Korea.

Amanda B. Marciel (B.S. ChemBio) isdoing graduate work in biophysics at theUniversity of Illinois.

Eric J. Shen (B.S. ChemE) has taken a posi-tion as an associate process engineer withValero Energy Corp in Martinez, CA.

Chelsea I. Teall (B.S. ChemE) is working asa failure analysis engineer at SunPowerCorp in Richmond, CA.

Benjamin D. Weil (B.S. Chem and EECS) isin the Materials Science M.S./Ph.D. pro-gram at Stanford University.

Tawni T. Koutchesfahani (M.S.ChemE) is in the OperationalDevelopment Program at Baxter

Healthcare Corp’s Bioscience Division andmakes his home in San Diego, CA.

Joseph J. Zakzeski (Ph.D. ChemE) is in theNetherlands doing postdoctoral research ininorganic chemistry at Utrecht University.

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Free Radicals Alumni Event and Campaign Kickoff: College demonstration specialist Lonnie Martinburns a donut in liquid oxygen while alums estimate the wattage of the resulting light.

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Friends of thecollege

MARINA BOUDART

Marina Boudart passed away on May 18,2009. The wife of Michel Boudart, a lecturer in our chemical engineeringdepartment and the William M. KeckProfessor of Chemical Engineering,Emeritus, at Stanford, she was an artist in many media and active in the StanfordUniversity Women’s Club. Besides Michel,she is survived by their daughter, threesons, and five grandchildren.

HUBBARD C. “BARD” HOWE, JR.

Hubbard C. “Bard” Howe,Jr. (B.S. ’50, BusinessAdministration), a closefriend of the College ofChemistry, died onOctober 2, 2009, one dayafter his 81st birthday. At

the time of his death, he was serving onthe UC Berkeley Foundation Board ofTrustees and was a member of theUniversity’s Benjamin Ide Wheeler Societyand “Bears in the Mountains.” He was particularly interested in the potential ofbiochemical engineering and syntheticbiology, and he asked for “homeworkassignments” in that field from our faculty.Bard and his wife, Gene, generously estab-lished and funded the College of Chemistry’sHubbard Howe Jr. DistinguishedProfessorship in Biochemical Engineering,currently held by Professor Jay Keasling.They have also contributed to the supportof chemical biology in the college, as well asto the Haas School of Business. A formerpartner of Clayton, Dubilier and Rice, aprivate equity firm, Bard also had been a managing partner of the NevadaManagement Group and had served on theboards of some 60 companies, many of

which had been financially troubled beforehe turned them around. He was an avidtennis player, sailor, fisherman and hunter.When Gene called to give us the news of hispassing, she stressed how important Cal hadbeen to Bard. In addition to Gene, Bard issurvived by his three sons and their families.

AlumniEldor R. Lehfeldt (B.S. ChemE)passed away on May 24, 2007.

We recently learned fromShulamis “Shelly” Bickoff (B.A.’40, PoliSci), the widow of

Emanuel “Mel” Bickoff (B.S. Chem), thathe passed away on November 18, 2001.

Clair A. Weast (B.S. Chem; Ph.D. ’43,Agricultural Chem), who made his career inthe food science and technology industry,passed away on April 27, 2009. He is sur-vived by a daughter, five granddaughters,seven great-grandchildren, and three great-great-grandchildren, and was preceded indeath by his wife, Elsie (M.S. ’40, Food &Nutrition Science), and one daughter.

Charles A. “Charlie” Anderson(B.A. Chem) earned an M.B.A.from Harvard Business School.

His career included positions as assistantprofessor of business at Harvard, VP ofMagna Power Tool Company, associatedean and professor of business administra-tion at Stanford Business School, VP offinance of Kern County Land Company,president and CEO of two of KCL’s sub-sidiaries, and president and CEO of SRIInternational, from which he retired in1980. Besides obtaining his private pilotlicense and enjoying barbershop quartetmusic, he served on numerous boards,including the Kansai Research Institute of

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Kyoto, Japan, and the UC BerkeleyInternational House. He also devoted timeto Lucille Salter Packard Children’sHospital and the Board of Directors ofCalifornia State Chamber of Commerce,among other volunteer public service. Hepassed away on April 17, 2009, precededin death by his wife, Betty, and survived bythree children, four grandchildren, andthree great-grandchildren.

Thomas H. Schultz (B.S. ’34; Ph.D. Chem)made his career with the U.S. Departmentof Agriculture and, in retirement, was awelcome guest at G.N. Lewis Era AlumniLuncheons. He passed away on June 1,2009, survived by his wife of 72 years,Florence (B.A. ’36), his son, Roger (B.S.’66, Mech Eng), two granddaughters, andtwo great-granddaughters.

Lowell V. Coulter (Ph.D. Chem)was a group leader on theManhattan Project and taught

briefly at the University of Idaho beforejoining Boston University’s chemistry fac-ulty where he served for over 35 years. Aschemistry chair at BU in the early ’60s, hegreatly expanded the department and builtits research programs. His own research inthe area of thermodynamic properties ofcompounds known as clathrates earnedhim election to the American Associationfor the Advancement of Science. He retiredin 1977. A supporter of the College ofChemistry, he died on May 2, 2009, prede-ceased by his wife, Leona, and survived bytheir daughter and son, four grandchildrenand two great-grandchildren.

Jacklyn B. “Jacky” Melchior (B.S. Chem)passed away on July 18, 2009. An East Bayresident, she and her late husband NortenC. Melchior (B.S. ’44, Ph.D. ’46, Chem) wereCollege of Chemistry supporters and regularand welcome attendees at college events.

A Long Beach resident for 78 years, Lee F.Warner (B.S. Chem) served as a radar tech-nician in World War II followed by a 35-

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year career at Shell Chemical. He died onJune 1, 2009, survived by Kay, his wife of62 years.

During his WWII Navy servicein the South Pacific, Victor M.Burkman (B.S. Chem) survived

the sinking of the Hornet. After medicalschool at Northwestern, he joined GlyerMedical Group in Mountain View, CA,where he practiced family medicine for 35years. In retirement, he traveled as a ship’sdoctor and became an award-winningmulti-media artist. He passed away onJanuary 20, 2009, survived by his wife,Virginia, a daughter, and two grandchildren.

William H. Taplin III (B.A. Chem), a resi-dent of Twain Harte, CA, passed away onMay 28, 2009.

Jacklyn T. “Jackie” Bort (B.S.Chem) and her husband, JosephP. “Joe” Bort (B.S. ’39, EECS;

JD ’42), raised three children in the EastBay, where she was an active volunteer inthe Berkeley Public Schools and the BoyScouts and Girl Scouts. She was a long-time active member of the ChristianScience Church of Berkeley and of manycivic organizations. Joe died in 1995, andJackie passed away on May 14, 2009, sur-vived by two sons, one daughter, and sixgrandchildren.

A veteran of the Manhattan Project,Gerhart Friedlander (Ph.D. Chem) madehis career at Brookhaven NationalLaboratory (BNL) where he was head of the chemistry department. His collabora-tive, pioneering research on how high-energy particles cause nuclear reactionslaid the groundwork for computer-generatedcalculations of nuclear reaction mechanisms,which form the basis for theoretical modelsstill in use today. He co-authored the classictextbook, Nuclear and Radiochemistry, andhe was the first editor-in-chief of ScienceSpectra. After retirement in 1981, Friedlander

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remained active at Brookhaven, mostnotably to form a BNL team that collabo-rated with European researchers on theGallex experiment, for which a Nobel Prizewas awarded to Brookhaven team memberRaymond Davis Jr. in 2002. Friedlanderpassed away on September 6, 2009, prede-ceased by his first wife, Gertrude Maas,and survived by Barbara Strongin, his wifeof 28 years, two daughters from his firstmarriage, four stepchildren, four grand-children, six step-grandchildren, and twogreat-grandchildren.

Victor P. Van Der Sterre (B.A. Chem) ofMillbrae, CA, passed away on March 10,2009.

After working on molecularspectroscopy with G. N. Lewis,Robert V. Nauman (Ph.D. Chem)

did postdoctoral research from 1947 to1953 with Peter Debye at Cornell andtaught briefly at the University of Arkansas,before joining the chemistry faculty atLouisiana State University, Baton Rouge,where he spent his career. He passed awayon April 25, 2009, survived by his wife,Jean, two daughters, two sons, and sixgrandchildren.

Herschel D. Davis (B.S. Chem)worked as a consulting archae-ologist and made his home in

Palm Desert, CA, where he died on March2, 2009. He is survived by his wife, Nancy,and a daughter.

Berton H. Wilson (B.S. ChemE) made hiscareer in petroleum refining at Chevronand, as part of the implementation of histanker fuel conservation program, traveledwith their shipping fleet. He lived inKensington, CA, and passed away on April11, 2009, survived by his wife, Patricia, sixsons, two daughters, eleven grandchildren,and one great-grandchild.

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Thomas C. Beiseker (B.A. Chem)worked at General DynamicsConvair after graduation and

went on to co-found Data-Design Laboratoriesin Ontario, CA. The company, which laterrelocated to Rancho Cucamonga, workedwith the submarine-launched Polarisstrategic weapons system and providedpersonnel and training to the subsequentPoseidon and Trident programs. He diedon August 12, 2009, at his home inChesterfield, MO, survived by his wife,Ethel, two children, five grandchildren, andeight great-grandchildren.

Escaping Nazi Germany in themid-1930s, Lieselotte J. “Lilo”(Kamm) Templeton (B.S. ’46,

Ph.D. Chem) came with her family to livein the Bay Area on the advice of her uncle,Otto Stern, the Nobel Prize-winning physi-cist who had spent a sabbatical here yearsearlier. After earning her doctorate, Lilo didresearch into techniques for explosivesdetection, working with chemistry profes-sors William Gwinn and Chester O’Konski,as well as for the Department of MaterialsScience and Engineering. She later con-ducted joint research with her husband,Professor Emeritus David H. Templeton(Ph.D. ’47, Chem), using X-ray diffractionat various wavelengths to determine crystalstructures of large, complex molecules, forwhich they were jointly awarded the A. L.Patterson Award. The strategies and tech-niques they developed have benefitted thefield of crystallography and the area ofresearch concerned with determining com-plex protein structures. In addition to theirscientific contributions, Lilo and Davidgenerously contributed to the well-being ofthe college and graciously attended numer-ous alumni and donor events. Her familygave us the news of her passing onOctober 10, 2009, at the age of 91. In addition to her husband, she is survived bytheir two children, Diana Killen and AlanTempleton. All who knew this remarkablewoman will miss her.

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John M. Boyles (B.S. Chem)worked as a chemist at Chevronin Richmond, CA. He passed

away on May 16, 2009, in Silver SpringsTownship, PA, predeceased by his wife,Nadya, and survived by two daughters andthree grandchildren.

We recently learned that AlbertT. Bottini (B.S. Chem) died onFeb. 3, 2002, in Davis, CA.

After earning his Ph.D. in chemistry atCaltech, he joined the UC Davis chemistryfaculty, where he made his career. He issurvived by his wife, Marilyn, three sons,and eight grandchildren.

Emil J. Volcheck Jr. (Ph.D.Chem), a supporter of theCollege of Chemistry, made his

34-year career with DuPont, primarily infabrics, retiring as manager of the DuPontExperimental Station in Wilmington, DE.In retirement he avidly pursued astronomyand computing as hobbies and laterexpanded these interests into communityservice. He managed the Mount CubaAstronomical Observatory, hosting and lec-turing at its Public Nights and overseeing aresearch effort on the observation of whitedwarf stars. He founded the Main LineComputer Users Group (MLCUG) and ranthe "Computer Forum” at the WestChester, PA, Area Senior Center. Volcheckdied on January 24, 2009, survived by hiswife, Diana, two sons, and a daughter.

Before starting college, WalterM. Gibson (Ph.D. Chem) hadalready worked as a shepherd,

done stunts for Western movies, andplayed saxophone in a dance band. In1958, he went to work for Bell TelephoneLaboratories in New Jersey, where he didgroundbreaking research in semiconductordetectors, radiation effects, and ion chan-neling, which led to the success of theTelstar satellite. In 1976, he took a positionas the chairman of the physics departmentat SUNY Albany, where he also served as

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acting vice president for research, dean ofgraduate studies, and the director of theCenter for X-Ray Optics. After retiring, heco-founded X-ray Optical Systems in EastGreenbush, NY, and served as its chieftechnology officer until his death on May15, 2009. A College of Chemistry supporter,he is survived by his wife, Alice, five children,20 grandchildren, and four great-grand-children, and is predeceased by a daughter.

Teresa (Nakahara) Appel (B.S.Chem) worked for more than 20years as a chemist for Anamet

Laboratories while raising two children withher husband, Bruce Appel (B.S. ’58, Chem).After 30 years in Berkeley, they retired toLa Jolla, CA, enjoying 15 years of travel andtime with grandchildren. She passed awayon June 9, 2009, survived by Bruce, theirtwo children and four grandchildren.

During his career at Stauffer inRichmond, CA, Don R. Baker(Ph.D. Chem) patented many

inventions and co-authored and editednumerous books on the synthesis andchemistry of agrochemicals. He died April24, 2009, predeceased by his first wife andsurvived by his wife, Shirlee, eight children,25 grandchildren, and three great-grand-children.

During his interesting and varied careerRichard M. Lessler (M.S. ’54, Ph.D. Chem)worked at Lawrence Livermore lab, theU.S. Nuclear Regulatory Commission, theUnited Nations, Bechtel, TRW, AerospaceCorporation, and, most recently, theEnvironmental Protection Agency in SanFrancisco. He and his wife Lillian, who survives him, have made generous provi-sions for the future creation of the RichardM. and Lillian Lessler Endowed Chair inChemistry. He passed away on August 12,2009.

Following graduation, David E.Breen (B.S. Chem) spent severalyears in the U.S. Navy and, in

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1969, moved with his wife, Marjorie, toMassachusetts where he worked as a pro-fessional safety engineer at Factory MutualResearch Corp., Harvard University,Northrop Grumman, and, most recently,Mitre Corp. They retired to Wellfleet, MA,in 1998 where he was on the Board ofHealth. He died on March 10, 2009, and issurvived by his wife.

Peter Sheldrick (Ph.D. Chem)dedicated his career to the studyof herpes viruses and is best

known for a fundamental discovery hemade at the Institut Pasteur in France thatbecame a foundation for all molecularanalyses of these viruses. He made hishome in France, and we recently learnedthat he passed away on January 7, 2008.

William “Bill” Breivogel (Ph.D.Chem) served on the chemistryfaculty of Chipola College in

Marianna, FL, for over 20 years. He diedon January 19, 2009, survived by his wife,Carmen, two children, and three grandchil-dren.

At the California Department ofPublic Health Services inBerkeley, Howard S. Okamoto

(M.S. Chem) made many contributions asa research scientist, including analyticalmethods that have been adopted by theEPA. He passed away on May 16, 2009,survived by wife, Charlene, a son, and agranddaughter.

Gregory D. Granger (B.S.ChemE) died on July 21, 2009.He earned a law degree from

McGeorge School of Law in Sacramento,CA, and practiced law in the Los Angelesarea. At the time of his death, he was a solepractitioner in The Granger Law Firm inNewport Beach, CA. Preceded in death byhis mother, he is survived by his father andstepmother, one sister, four brothers, andhis three children.

compiled by dorothy read

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Date

Name

UC Berkeley degree(s)

Degrees from other institutions

Spouse/Partner’s name

Home address (New info? )

Work or school (New info? )

Preferred mailing address: Home Work

Preferred email address: Home Work

Name and address of someone who will always know how to contact you:

FOR CLASS NOTESTell us your news: recent promotions, family additions, an exciting trip . . .

I grant permission for the use of this information in College of Chemistry publications and the alumni directory

I do not grant such permission

I want to join the Alumni Association (it’s free!) and receive announcements

I want to help by:

Participating in future planning for the association

Planning events in my area (with the assistance of the college)

I am interested in participating in the following:

Lectures or Symposia Career Networking Social Events

title first name middle name last name previous name

degree(s) year department

street

city state zip phone email

street

name of organization academic department or company division

city state zip phone email

street city state zip phone email

signature granting permission

name relationship

position job function start date

CatalystAlumni Questionnaire

chemistry.berkeley.edu

FOR OFFICE USE ONLY

DR AA

DE CR

CN

degree year dept/major

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university of california berkeleyCollege of ChemistryCollege Relations and Development420 latimer hall #1460berkeley, ca 94720-1460

f i r s tc l a s spostageh e r e

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annual report ’09

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all colors are fading, classes are in full swing and our increased enrollment shows that studentsrecognize the chemical sciences as the portal to a wide variety of careers in science, engineering andmedicine. While the seemingly never-ending budget challenges continue to demand our attention, wehave nonetheless worked together in the College of Chemistry to advance a number of projects aimed

at improving teaching, research and facilities. I want to express my thanks to the numerous alumni, parents, friends, faculty and staff who are recognized in this annual report for their support. I feel a deepsense of gratitude knowing that support from our constituents is something we can always count on.

The College continues to provide fertile ground for the advancement of bold new instruction and researchideas in the chemical sciences. As we look toward the future and the exciting possibilities ahead, I find a great sense of satisfaction knowing that you support us. As an alum and parent of a newly admitted student said recently, “In times like these, you know who your friends are.” I’m proud to count you amongour friends.

SOURCES OF PRIVATE FUNDS

Individuals $1.35 M 26.9%

Corporations/Corporate Foundations $2.52 M 50.2%

Private Foundations/ $1.15 M 22.9%Nonprofit Organizations

Total $5.02 M 100%

USES OF PRIVATE FUNDS [ENDOWMENT]

Chairs $0.52 M 72.2%

Student Support $0.12 M 16.7%

Unrestricted $0.03 M 4.2%

Research $0.04 M 5.5%

Capital $0.01 M 1.4%

Total $0.72 M 100%

USES OF PRIVATE FUNDS [OPERATING]

Research $2.63 M 61.2%

Student Support $0.59 M 13.7%

Unrestricted $0.74 M 17.2%

Capital $0.34 M 7.9%

Total $4.30 M 100%

22.9%50.2%

26.9%

16.7%

4.2%5.5%

17.2%

7.9%

1.4%

13.7%61.2%

72.2%

f i n a n c i a l s

2009of private givinga n n u a l r e p o r t

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CumulativeClubs

CaliforniaBenefactors

$1,000,000 and more.

AnonymousNorbert C. and Florence M.Brady

Dr. and Mrs. Nirmal ChatterjeeChen Yu-HowT. Z. and Irmgard ChuAldo DeBenedictis EstateDr. Melvin J. Heger-Horst TrustMr. and Mrs. Hubbard C.Howe, Jr.

Gunawan JusufRoss McCollum TrustJean Mosher PitzerPitzer Family FoundationDr. and Mrs. Warren G.Schlinger

Ann E. Shiffler EstateDr. and Mrs. James R. TretterRobert Tsao

The Blue andGold Society

$500,000 to $999,999.

AnonymousLarry and Diane BockChen He TungDr. James O. Clayton EstateWarren E. CliffordGus D. DoroughHenry F. Frahm EstateRichard M. and Lillian LesslerIrma McCollum TrustDr. Reid T. Milner TrustBeatrice Thomas EstateMarie W. Woodward Estate

The 1868 Society

$100,000 to $499,999.

Anonymous (5)Mary ArnettUsman AtmadjajaLeo A. Berti EstateBud BlueThelma Buchanan EstateSunney Ignatius ChanChng Heng TiuMrs. Antonio T. ChongRobin D. Clark and Mary Mackiernan

Chester W. Clark EstateFrank and Janice DelfinoDrs. Thomas J. Dietsche andLaura J. Dietsche

Dr. Sam H. EletrWilliam and Janet GerhardtSuhargo GondokusumoG. Douglas and Regina GouldProf. and Mrs. John E. HearstProf. Darleane C. and Dr. Marvin Hoffman

Robert and Yasuko IkedaStephen T. Isaacs and Kathryn Macbride

Harold and Mary Ella JohnstonKiong Yo KianEngr. Joseph L. Koo andHelen C. Koo, M.D.

Prof. Daniel E. Koshland, Jr.Joseph M. and Dorothy K.Kunkel

Lee Sheng PengAnnie L. LiLiem Sioe LiongWesley and Elizabeth LindsayEstate

Tony K. and Louisa LingLie Shiong TaiProf. Bruce H. Mahan EstateMr. and Mrs. Alan C.Mendelson

Dr. and Mrs. Joon S. MoonDr. Robert N. NoyceS. M. “Jack” OlsenMarjorie Pape Crandall PearceJonathan S. PowellDr. Mochtar RiadyMilton H. and Ethel M. RitchieKlaus and Mary AnnSaegebarth

Patricia M. SchreterMr. and Mrs. John W. Scott, Jr.William H. ShifflerDr. Charles E. Stehr and Mrs. Dorothy H. Stehr

Tan Keong ChoonHenry K. TomMrs. Theodore VermeulenDoris H. Welles EstateEka Tjipta WidjajaCharles R. Wilke EstateEugene T. C. Wu

Annual GivingClubsGifts received in 2008–2009

The LewisAssociates

$50,000 and more.

Anonymous (2)T. Z. and Irmgard ChuGus D. DoroughDrs. David S. Gee and Caryn C. Q. Lum

Mr. and Mrs. Alan C.Mendelson

Pitzer Family Foundation

The LatimerAssociates

$10,000 to $49,999.

AnonymousDr. Nirmal and Mrs. EllenChatterjee

Robin D. Clark and MaryMackiernan

Warren E. CliffordDean and Becky DraemelWilliam and Janet GerhardtVic and Faye GuntherDavid G. KarrakerDavid E. KeplerEd KimDonald M. Leslie EstateRichard M. and Lillian LesslerArturo MaimoniGus Malmquist EstateDean Richard and Mrs. Jo Anne Mathies

Carlos and Patricia NuilaPatricia M. SchreterProf. David and Dr. LieselotteTempleton

The GiauqueAssociates

$5,000 to $9,999.

Charles E. and MarianneAuerbach

Prof. Paul A. Bartlett and Dr. Yumi Nakagawa

Edwin D. BeckerNorman BonnerArdra C. BrodaleTim and Valerie BruemmerSunney Ignatius ChanRonald L. ClendenenWilliam A. DanielsThomas and Martha De JongheFrank G. Delfino


30

donors to the college The first three donor clubs listed—the

California Benefactors, the Blue and Gold Society and the 1868 Society—are cumulative clubs.

Donors’ lifetime giving to the College of Chemistry determines their club level. The remaining clubs

are annual—the club level shows each donor’s giving during the 2008-2009 year.

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 30

annual report ’09

31

Drs. Thomas J. Dietsche andLaura J. Dietsche

Pete Dragovich and Pei-Pei Kung

Julianne Elward-BerryRocky L. Freel and Nancy Skilling

Dr. and Mrs. Theodore H.Geballe

Gene I. IwamotoProf. Harold and Mrs. Mary Ella Johnston

Dr. and Mrs. Andrew KaldorChi-Tzu KaoEdward F. KleinmanLaRoc and Linda KovarProf. Stephen R. Leone andDr. Mary K. Gilles

David Lieu, M.D., M.B.A.

Gary and Irene MasadaCurtis Lee MunsonAlbert NarathDaniel and Ellen NeumarkProf. Heino Nitsche and Ms. Martha Boccalini

Louise Lyon Quenon andMichel Quenon

Prof. Jeffrey A. and Ms. Karen B. Reimer

Ann E. Shiffler EstateTonny and Fay SoesantoDr. Charles E. and Mrs. Dorothy H. Stehr

Barbara A. TenenbaumProf. Don and Mrs. RosemaryTilley

Michael G. ValentineWillard M. Welch

The SeaborgAssociates

$2,500 to $4,999.

Anonymous (2)Ronald J. and Sue A. BanducciJohn H. BirelyJohn B. BushDanny ChenRobert ChinnJohn F. HeilJoseph R. HomlerHerbert HooperVictor W. T. HuangKiyoshi and Irene KatsumotoStanley KellyWilliam A. KleschickVirginia and Frank Lew

Tim MontgomeryHerb NelsonJoan Friedman Newmark andRichard Newmark

William R. ParrishProf. Norman and Mrs. PaulaPhillips

Darwin and Donna PoulosProf. and Mrs. John M.Prausnitz

Frank and Annette RahnKlaus and Mary AnnSaegebarth

Steven SciamannaJane N. ScottSher G. SinghEric R. SirkinMr. and Mrs. John R. SkinnerClinton D. and Sharon SnyderRichard M. TeeterBruce T. VermeulenRaymond VermeulenRita Wieland

The WilkeAssociates

$1,000 to $2,499.

Profs. Juana V. and AndreasAcrivos

Keith Alexander, Ph.D.Mr. and Mrs. Myron AndrewsDennis P. BauerRichard Behrens, Ph.D.William Benjamin, Ph.D.Prof. Robert and Ms. WendyBergman

Prof. Harvey W. BlanchM. Robert BlumR. R. BreckenfeldMichelle BrodaleRichard BrodzinskyMarilee BrooksDavid and Donna BrownCharles Buse

benefits of private giving

THE TONG AWARDCalvin Huynh was born and raised in San Jose. He’s an undergraduate working with the researchgroup of Chris Chang, where he is developing new sensors for detecting H2O2 in living cells. Heplans on attending a graduate program in pharmacy after his graduation from Berkeley in thespring of 2010.

The James Y. and Harriet P. Tong Chemistry Award encourages outstanding undergraduateresearch. The award was established by Ohio University Professor Emeritus James Y. Tong (B.S. ’50,M.S. ’51, Chem) and his wife Harriet, who met each other at the UC Berkeley International House.

Calvin Huynh

“The Tong Award allowed me tocontinue my research duringthe summer of 2009, throughwhich I have been able to growintellectually and develop myunderstanding of the role ofhydrogen peroxide in normalphysiology and diseased states.”

15574_1.p31.32.crx_Layout 1 12/11/09 12:11 PM Page 31

William H. CalkinsProf. Joseph and Mrs. SusanCerny

Edmund ChambersDavid ChanS. Kumar and UmaChandrasekaran

Yuenyee M. ChengFannie ChongDr. Tung-Jung ChuangProf. Robert and Dr. FrancesConnick

Robert S. CrowderEric DarmstaedterThomas and Cynthia DelfinoWalter and Eleanor DongClelland R. DownsMarissa DrouillardHelen M. ElliottWalton EllisGail G. Engerholm

June S. EwingVirginia and Larry FaithSteven and Terri FantaziaWilliam E. FogleJennifer FujiiShun C. FungMan K. GoWataru and Tuyet GoishiCharles and Karen GossG. Douglas and Regina GouldJoan T. GreenElaine and Arnold GrossbergFanqing GuoEric HaasDr. David R. HansenProf. Charles B. HarrisBarry P. HartProf. Clayton Heathcock andDr. Cheri Hadley

Joel Hill

Robert P. HohmannWilliam and Hoi-Ying HolmanRichard W. HymanYasuko IkedaMark J. and Alice H. IsaacsonErnest JacobsonStephen and ElizabethJohnson

Darren C. JonesJohn Jost, Jr.Gary and Patricia KaiserDr. Max J. KalmPaul H. KasaiProf. Hyun Yong KimProf. and Mrs. C. Judson KingDr. and Mrs. Fred KirbyKevin A. KlotterHenry F. KoopmannP. G. KoskyJ. Clark Lagarias

James and Barbara LagoPeter W. LeeSoo-Ying LeeRobert and June LindquistDayna and Peter LucasDick and Myra LynchScott and Annette LynnProf. Samuel and Mrs. LydiaMarkowitz

Prof. Michael Marletta andMs. Margaret Gutowski

Michael McCormick, M.D.Alison McLeanThomas J. MeyersRichard D. NewmanKenneth OttesonSunil PatelChin-Tzu PengDr. Donald D. PhillipsLlad PhillipsJeanne PimentelJacob PlattnerJohn A. RaganDavid L. RehderJohn L. RobbinsDavid B. SableMarcia SableProf. Richard Saykally and Ms. Chris Read

Fritz and Karen SchaeferGeorgieanna L. ScheuermanBill SchriverWilliam and Virginia SchultzGary P. SchwartzManesh and Margarita ShahKaren and Scott SibbettRonald E. SilvaRandy SnurrJeffrey P. Solar and Rosalyn Furukawa

Mike Solomon and Ellen LeeMrs. Judith and Prof. GaborSomorjai

George and MaradelSonnichsen

Linn SpechtThomas M. StachelekPeter J. StangBruce E. and Susan J.Stangeland


32


THE DORSEY AWARDBorn in Honolulu, HI, Jane Wang graduated from Caltech with a B.S. in chemistry,where her mentor was Robert Grubbs, 2005 Nobel laureate in chemistry and College ofChemistry Advisory Board member. As a member of the research group of Dean Toste,she explores new avenues of research that use organic and organometallic chemistry totackle problems in biochemistry and material science.

The Andrew D. Dorsey MemorialAward was established by David andKlara Dorsey to honor the memory oftheir son Andrew, a chemistry graduatestudent who died suddenly of a brainhemorrhage in August 2001.

Jane Wang

“Teaching as a graduate studentinstructor at Berkeley has been areally unique experience, and I think it’s wonderful that the DorseyAward supports us in this area!”

15574_1.p31.32.crx_Layout 1 12/11/09 12:11 PM Page 32

Donna R. SterlingMs. Carolyn North and Prof. Herbert L. Strauss

Prof. Andrew Streitwieser andMs. Joyce Hessel

Michael J. Sullivan and Ellie Y. Yieh

J. and K. SuryaBruce Gerald SzczepankiewiczKong-Heong TanAnne Friend ThacherHuijun TianCurtis M. TongCharles C. TranHarvey S. TropConstantine TsonopoulosDale E. Van SickleMrs. Theodore VermeulenJames P. Vokac and Stacey T. Baba

Andrew WangRaymond Chiu and Stephanie Wang

Kathleen M. Welsh, M.D.David and Joanne WemmerKeith R. WestcottRobert Wilhelm and Sun Hee Wilhelm

Roger G. and Molly W. WilliamsGar Lok WooFrank WoolardStephen WorlandSung C. and Gia K. YiSteve YoungWilliam R. Young

The Calvin Club

$500 to $999.

Anonymous (3)Arthur and Frances AbramsonCarlo and Barbara AlesandriniProf. Paul and Mrs. NicoleAlivisatos

Steven M. BachrachMichael L. BarryNader BayatMarvin and Judith Brafman

annual report ’09

33

Timothy, Susan and ThorBreece

Matthias BremerMichael J. BuckleyLucinda F. Buhse and Steven A. Kinsley

Joel BurleyMichelle and Jeffrey ChangAndrew Y. ChengJ. Peter and Nancy L. ClarkJohn W. ColletteDonald R. ColvinPeter Connolly and Pauline Ting

John E. CriderMatthew Shane CroughanSheryl and Kenneth DahlTimothy and Suzanne DevittRonald DickensonRochelle and Robert DreyfussArthur K. DunlopWilliam E. DunnRudolph H. DyckVictor and Louise EnglemanNicholas A. FedrickGeorge A. FiskMichael and Mary FlaughProf. Graham Fleming andMs. Jean McKenzie

Stanley W. FongPhilip R. FriedelFriends of Eric AbramsonScholarship Fund

Drs. Thomas R. Gadek andKatherine Neldner

Frank P. GayMichael B. GentzlerWalter M. GibsonGrant W. HaddixMr. and Mrs. SoonKap HahnMarlin D. HarmonyScott J. HeckerDuane HeymanToshiaki HinoDennis and Dale HirotsuKeelung HongJudy C. Huang and Ken A. Nishimura

David R. and Karen W.Johnson

Prof. Jay D. KeaslingJack KellyChung-Pai KimProf. Sung-Hou and Mrs. Rosalind Kim

Andrei W. KonradiDeanne C. KrenzJessica LamRich LawtonMarc and Tsun-Tsun LevinMark T. LewellynEdward S. LewisJames W. Lewis and Dale A. Roche

Kwang-Chi and Shin-ShinLiang

Wes LiangArnold A. LiebmanDavid A. LightnerRichard M. Lim and Terate B. Nalukas

Nelson LinPeter and Rachel LipowiczMr. and Mrs. Henry LooXiaojun Ma and Xiaodong WuJane and Michael MacDonaldMary M. MaderProf. Bruce H. Mahan EstateCraig MarkeyThomas A. Massaro, M.D.Dr. Eugene D. McCarthyJames A. McHughRon MeekerDrake and Jayne MichnoMichael J. MillerCapt. Peter W. MillerLingfung MokPaul E. MorrisroeEstella K. MyselsAllen NgDouglas NgKenneth T. NgoDavid A. O’BrienEdward John PalkotGarry Lain George PartonJoe and Ann PeaseDavid B. PhillipsJoan and Rich PhillipsAndrew RamelmeierGurdeep S. Ranhotra

Elmer and Helen ReistWilliam G. RixeyJoel W. RosenthalArnold and Janice SeiduleStephen and Lila ShainHenry B. SinclairGerald SmolinskySouthern CaliforniaEngineering AlumniAssociation

David F. StarksDavid SternMark and Nancy StoyerJack D. SwanburgJames S. SymanskiSugihiko TadaMasato and Miyeko TanabeThe Tellers FamilyProf. Ignacio Tinoco and Dr. Bibiana Onoa

Petra N. TurowskiEmil Volcheck, Jr. FamilyLeigh M. WarrenKaren M. WebsterMark Wegner and Mary KornCharles W. WeiGreg WentDr. Richard J. WilcoxPhillip A. WilmarthRay WonWilliam Allen WoodFonda B. WuKatsumi YamamotoSachio YamamotoEric Pao Yan YangJianbo Zhang and Shiyi Ren

The Tobias Club

$250 to $499.

Christina C. AlmendralaAnonymous (2)Daniel and Shelley ArensonBurke and Carole BakerKaren Jernstedt and Jim Barkovich

Bruce N. BastianStacey Bent and Bruce Clemens

donors to the college

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 33

Klaas BergmannSteven and Sandra BernasekConstantine G. BoojamraMarie T. Borin, Ph.D.John and Claire BoursalianLawrence J. BowermanJohn J. BrodbeckGina BuccellatoWilliam H. BuchanJames D. BurkeC. Hackett BushwellerHalbert H. CarmichaelMichael F. CarolanFrank D. CervantesJoseph and Sara ChanPhilip L. ChanEdward Robert ChanezonChu-An ChangShih-Ger (Ted) ChangShiuan ChenMarina M. ChinLeland J. ChinnMichelle Claffey and Stephane Caron

Maria T. ClarkRonald N. ClazieGeoffrey K. CooperHarold CotaRobert and Debora Couey

Dr. Calvin J. CurtisChristopher DateoJed E. DavidowStephen G. DiMagnoStephen E. DinizoGalen DowntonDr. Lawrence H. DuboisCarol DunbarMichael J. DuretLois J. DurhamProf. Jon and Mrs. Pam EllmanKenneth G. FeltonElisa FernandesBruce A. Firestone, Ph.D.Ian FisherReyes M. FragosoTim FrederickPete FullertonKent FungNorman L. GarfieldMarjorie M. GasserPeter GatesWilbur Y. W. Lew and Bertha M. Gee-Lew

David J. GodbeyAbraham GoldhaarSamuel L. GrahamJoseph M. GreendorferWilliam Guilford

Lara A. GundelPaul H. GuscioraWilliam GuthrieGuenter HafelingerDavid J. HartDerek J. HeiRobert and Ellen HemptonDr. and Mrs. Frank HernandezFrank HershkowitzRobert HickmanDon HildenbrandJason HoElvin L. and Donna I. HoelRichard and Patricia HoffMei-Shel HonRichard HonnellR. F. HumphreysWilliam Y. JaPaul J. JansenJack JewPatricia A. JonesMichael J. KaufmanEsayas KelkileBrian D. KelleyJohn KindsvaterEdward L. KingJames A. KleinProf. Judith KlinmanCamey Ku

Howard LacheenKaren W. LaiStephen M. LambertBart LarrenagaFrances LeeDaniel LevaTraci A. and Timothy A. LewisSteve and Helen LimGlenn LipscombDr. Francis J. LovasGuowen Lu and Zheng ZhangRobert LundinPatricia D. MackenzieJon MaienscheinGregory S. Girolami and Vera V. Mainz

Kevin McAleaPatrick McGrathKenneth E. MeekerProf. and Mrs. Howard C. MelJohn G. MengsholRichard L. MersonMichael MilosDavid W. MorelandSean P. MullenRichard J. Nagle, Jr.John B. NashJames W. NeelyHarry T. (Tom) Nelson


34


Lewis Associates$50,000 and more

(formerly California Associates)

Named for Gilbert Newton

Lewis, the college’s first dean.

Latimer Associates$10,000-$49,000

(formerly Berkeley Associates)

Named for Wendell Latimer,

professor of chemistry.

Giauque Associates$5,000-$9,999

(formerly Gold Sproul Associates)

Named for Nobel laureate and

chemistry professor William F.

Giauque.

Seaborg Associates$2,500-$4,999

(formerly Blue Sproul Associates)

Named for Nobel laureate

and chemistry professor

Glenn Seaborg.

College of Chemistry Annual Donor Clubs

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 34

Frederic T. Selleck, Ph.D.John L. ShaferStephen ShapiroAnita J. ShawYaoming ShiDonald and Carmen ShiosakiProf. Kevan ShokatJerry Richard ShuperAb Siadati, M.D.Hugh C. SilcoxJohn A. SmegalJoseph P. SmithTravis L. SmithShinji and Masuko SonedaDrew V. SpeerJulie StewartNeil C. StipanichDr. John B. SwartzJeffrey TaneJerome H. and Selma E.Targovnik

David G. TaylorDavid and DeborahThompson

John F. ThompsonKen TokunagaTracy Phuong Tuyet Tram, M.D.Richard UnderwoodJung Ku and Tetsuo Uno

Dr. David R. NethawayNancy NoremJohn J. O’BrienJohn F. O’ConnellCamille and Jim OlufsonOgbemi and Cecilia OmateteStephen ONeilKent OpheimKeith PangJames PapanuAxel Helmut PaulSundiep (Tehara) PhanseRichard C. Pilger, Jr.Bava PillayAustin and Marjorie PrindleFrank T. ProchaskaRoland QuongJack M. RademacherProf. Clayton RadkeRonald RatcliffeMindy Rex and JohnDischinger

Neil Lawrence RickerJames A. RoeFerenc and Diane RosztoczyProf. Harry N. and Mrs. Jane L.Scheiber

Erika Schneider, Ph.D.Alan and Gail Searcy

Jack Van Den BogaerdeDrs. Robert and Susanne E.Vandenbosch

James and Jennifer VarleyErich R. VorpagelDeane Stefan WalkerTimothy P. WalkerLisa WangSheldon A. WeberFred and Cristel WemerCharles T. WhiteHeather D. WhitleyJames D. WillettJack WongRichard F. WormsbecherRobert ZahlerWilliam T. ZimmermanPaul F. Zittel

The HildebrandClub

$100 to $249.

Abhay Acharekar andNirupama Pujare

Dr. Raul E. AcostaJohn E. Adams

Jeffrey and Tracy AdkinsRodel and Beverly AgresorAnonymous (4)Dr. and Mrs. David AltmanJames and Jacqueline AmesAllan AndersonEdward and Florence AoyagiEvan and Mary AppelmanDr. John D. ArenivarMorris and Stephanie ArgyleDon W. ArnoldDr. John Arnold and Ms. Jennifer Shaw

Frank and Lucille AsaroLucienne AshJ. William AubrySteven C. AvanzinoSamuel D. BaderDouglas J. BamfordElizabeth Hodgins BartkyCraig P. BaskinRussell H. and Carolyn C. BattDr. David Beach and Ms. Roxana Beach

James R. BeckJohn Bedbrook and Pamela Dunsmuir

Gay BellRobert and Jackie Bellerose

annual report ’09

35

ciates)

Wilke Associates$1,000-$2,499

(formerly Robert Gordon Sproul

Associates)

Named for Charles Wilke, pro-

fessor of chemical engineering.

Calvin Club$500-$999

(formerly Sather Gate Club)

Named for Nobel laureate and

chemistry professor Melvin

Calvin.

Tobias Club$250-$499

(formerly Carillon Club)

Named for chemical engineering

professor Charles Tobias.

Hildebrand Club$100-$249

(formerly Campanile Club)

Named for chemistry professor

Joel Hildebrand.

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 35

Janet E. BercovitzMarina BerdichevskyCarl M. BerkeRichard N. BiagioniJacob BigeleisenPaul BigeleisenRyan BisePaul D. BisioRobert BittmanMary Frances BlackwellPatty and Bill BlantonTodd A. BlumenkopfRichard BodenJerome V. BootsGeorge A. and Syble F. BoswellDavid E. BreenRobert J. BreuerLeo D. BrownSandra M. BrownEdward BruggemannFrederick L. Burnett IIICarol J. BurnsGary P. BurnsKristina M. BurowThomas and Eileen BuschingCharles Nicholas BuserJohn H. BushwellerProf. and Mrs. Elton J. CairnsJames L. CaleyMark CamenzindWayne M. CamirandJonathan O. CarlsonJohn P. CarrEmily A. CarterDavid C. CastagnolaJames L. ChaoRoger and Eileen ChaoMu Jung ChenGrant ChinCollette ChingYong-Hwee ChuaDick T. CoKenneth E. CoatesF. Warren ColvinMorgan P. ConradMary M. ConwayDavid and Abbey CookFred F. CoonsJohn F. Cooper

Paul A. CorneliusTucker CoughlenKerry CrayEfren and Maribel CuevasDavid L. CullenRichard C. and Janet L.Cummings

Bo CurryChollada DarakanandaDavid C. DarwinDrs. Cameron and Jean DaschPravin and Jyoti DattaniDr. Jefferson C. Davis, Jr.Kenneth E. De BruinJohn and Nancy DevincenziShyamal P. DharmasenaHenk DijongCharles Do, M.D.

Phuong Nhu Sy DongMichelle Christine DouskeyDenis and Donna DrapeauSteven F. DruryDoug EdwardsErnest Ehnisz, Jr.David J. EllisMark R. EtzelJohn FaberaStephen FallingEric FallonHeather FanSimon Fang and Jie LongMaria Fardis, Ph.D., M.B.A.Jim and Nina FarjadiPeter and Sharon FedkiwJ. Leonard FickDwight A. Fine

Milton FingerBrian FischerJay and Leslie FishmanWarren W. FlackFred and Helen FongBruce M. ForemanGirard (Jerry) FosterMary M. FoxElizabeth FrancoisValerie Jue FrancuzLoyd D. FrashierAllen H. FrederickCraig S. FrialCharles R. GahrEthan C. GallowayTerry GallowayDon GartnerSteven and Hillary Garwin


36


THE DOW EXCELLENCE IN TEACHING AWARDJarred Ghilarducci was born in Bakersfield, CA, and earned his B.S. in chemical engineering atUCLA. As a Berkeley chemical engineering graduate student, he studies rational catalyst designwith professors Alex Katz and Enrique Iglesia.

The Dow Excellence in Teaching Award is anannual gift from the Dow Chemical Companyto recognize outstanding graduate studentinstructors in the Department of ChemicalEngineering.

Jarred Ghilarducci

“Getting to work closely with the studentshas made being a GSI the most rewardingexperience I’ve had at Cal. I often drewfrom my own experiences as an under-grad to help my students avoid the samepitfalls I once encountered. Although thestudents have been my real inspiration, itis nice to have my hard work recognizedby Dow.”

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 36

Ted and Deborah GermrothKevin R. Geurts and Angela R. Smith

Peter GiannousisJack T. GilmoreGary M. GoncherJudson E. GoodrichMark and Valerie GoodwinBruce A. GordonDaniel M. GoreckiGeorge W. GothHarold and MargaretGranquist

Ronald W. GrantBeth and Timothy GraselLaura GreenfieldRuth GrimesCharles E. "Ched" GrimshawWilliam A. GuilloryRobert GuntherHari B. GuptaWilliam R. HaertleHowell A. HammondRobert W. HandAndrew HarautuneianJohn and Angela HarderGeorge L. Hardgrove, Jr.J. Ronald HargreavesWilliam and Janet HargreavesEverette HarrisIan HarrisSteven Leopold Hartford,M.D., Ph.D

Tom HarveyMichal and Timothy HawkAuda K. HaysZesheng He and Yuelan ZhouJames and Jeannine HealySue HeinemannMax and Audrey HelixAdam HellerRay and Cathy HellerRobert T. HendricksRobert W. HermsenLloyd HilePaul V. HinmanEric HintsaHansel HoRobert B. Holden

annual report ’09

37

donors to the collegeAl and Juli HongJi Sun and Myeongsook HongDavid W. HooverLimin HsuehChung-hwa HuangE. Kenneth HuletJohn T. HuntPenny L. HunterJohn and Louisa HwaAnthony T. IavaroneDenise C. Jamin HaniseeMr. and Mrs. Thomas J. JarvisCraig JensenRonald JensenJohn A. JensvoldJon A. JohnsenAudrey JohnsonGary and Ann JohnsonPatricia W. and Russell L.Jones

Eileen M. JulianShee Lup JungDrs. John and Kristy JurchenAndreas V. KadavanichRichard A. KahlstromJames S. KaneAbdul R. KassirAlexis I. KaznoffAndrea L. KeatonEric R. KeimEllen KickHabtemariam T. KifleJohn S. KillianKathleen V. KilwayChung Wha KimAndrew KindlerTodd KindorfBaldwin KingJeffrey L. KlausAlice N. S. KoArkady and Lyudmila KokishTrudy KongAlan and Tracy KoretskyKenneth KrausMarvelle E. KrenzKamala R. KrishnaShailaja KrishnamurthyPaul J. KrusicSamuel S. Kurita and Mary Anita Long

Alex and Maria KutasHeemun KwackHarrison and Jeong Ok KwonJustin KwongCam-Mi LaRandel and Sheralin LaffertyFelix S. C. LaiJohn R. LaiEdward D. LallyLarry P. LamArnold LambWilliam E. LambertLee LatimerWilliam J. LawrenceLuong H. and Sophie L. LeChristina J. LeeChun-Yue LeeCindy LeeJess and Kiet-Nghi LeeMarianne AsaroM. K. Carol LeeTerrance Y. LeeAllen and Phyllis LefohnTheodore J. LeiteregJames R. LemleyProf. and Mrs. William A.Lester, Jr.

Albert C. H. LeungCissy LeungKeith LeungTak LeungDr. William G. LightBernard Joseph Lilly, Jr.Chee M. LimHong and Uong LimJames LimJack LinJon and Ren-Chih LinDr. and Mrs. T. Joseph LinTim LinNancy J. LinckManfred LindnerDavid LindsayNorma B. LinskyBenjamin T. LiuPamela LiuYan and Yvonne LiuDavid A. LloydZhi-Heng Loh

Harold R. LohrDr. Wayne D. LukeKa LumXuan Hung and Van Gia LyLuzviminda and RamonitoMac

Tom Mac PheeKhorshed MadanRajinder K. MahendrooBen and Kazako MakishimaDoug MandelNolan MangelsonW. Paul MartinCon and Mary McCormickDr. William R. McDonellJames W. McFarlandAnne E. McGuireKeith and Liz McLaughlinTanya and Michael McManusAshish J. MehtaShu-Hua MengJohn Mersch IIIJ. Hoyt MeyerRichard Michelman and Karen Meyer

Alwin S. MilianDonald G. MillerRichard R. MillerProf. and Mrs. William H.Miller

G. MitraBarbara and Dennis MorrellShawn J. MorrisseyLester R. MorssEarl M. MortensenRobert MortlockJim MuirheadRobert and Susan MullenBarry T. MurpheyThomas F. MurphyDr. and Mrs. Louie A. NadyTatsuhiko and MihokoNakashige

Masato NakashimaMarshall Douglas NelsonMadeline M. NettoThomas W. NewtonKing T. NgSteve Ng and Lynn Tangudtaisuk

15574_1.28_45_Layout 1 12/9/09 1:08 PM Page 37

Yu Sim NgFelix G. NganTuan Ngoc NguyenJiu X. NiKendall Novoa-TakaraTeiichiro OgawaMiles OkinoTimothy and Bobbi OlsonHoward K. OnoPatrick J. OrmeTim OwensJames OziomekSpyridon PapadakisRudolph PariserDr. Christopher C. ParksAlan D. PasternakColonel Douglas A. PattersonCharles W. PaulCharles PaulsonChih-Yuan and Shiau-ShiauPei

Arnold Leo B. PenedaCharles and Marilyn PerrinJaan PestiDr. Eric C. PetersFrederick M. Peterson, Ph.D.Leonidas PetrakisPaul A. PetruzzelliJason PloegerMatthew PlunkettJ. Kenneth PoggenburgMax Y. PongGary and Lily PoonDr. J. Winston PorterKristala Jones PratherMax PrayElisabeth M. PriceSusan PugliaDavid RabbDonald L. RaimondiChakkodabylu and SukanyaRamesha

Tom and Betty RansohoffStephen and Greta RegisterManfred G. ReineckeRichard A. ReinhardtEdgar and Rowena ReyesAntonio J. RiccoJed Richardson

Alice and Rudolph RicoJohn and Annette RiordanGene RobertsPatrick A. RodgersMark RoebuckDavid P. RogersLois V. RolandGerry RollefsonEsther H. RoseAlbert J. RothmanRobert J. RothwaySteven P. Rucker and Rebecca L. Hoff

David S. RumschitzkiEdna (Sugihara) SakaiRobert E. SantiniProf. Richmond SarpongAlexander SassiRob ScarrowRobert A. ScherrerFrancis and Phoebe SchmitzJoseph SchohnNick R. SchottJoshua A. SchrierPeter SchubartStephen E. SchwartzGretchen M. SchwenzerWilliam J. ScottRichard SearleJohn M. Seelig and Helen Zelt-Seelig

Pi-teh ShenLillian R. ShepherdGeorge S. SheppardAlbert E. SherwoodMartin D. ShetlarJames S. ShirkRobert D. SimpsonWade and Avril SiskKin and Monita SiuMyron SiuElliott B. SlamovichArthur C. SmithMichael E. SmithMercedes SniderSabrina G. SobelLee G. SobotkaSteven G. SogoJohn E. Sohn

Harry and Margaret SpencerCarla St. Laurent, M.D.William L. StanleyVirginia StarkRaymond C. StewartJoel A. StinerSteven and Gloria StoltzElaine Blatt StonerMichael S. StoryManolis StratakisPieter StroeveE. Thomas StromWarren C. StuebenLouis S. StuhlJohn P. SullivanChris TaggeJames Takasugi and Karen Brown

Gordon TamSarah Luchansky and Kian TanFred TanakaTony TangMarc E. TarraschJames G. TaylorReema K. ThaljiKlaus H. TheopoldJack ThomasKimberly and Kenneth ThomasJeffrey TomConnie C. TongLee Karl Jan TongPaul TongProf. Dirk TraunerMichael TrenaryGail A. TrimbleJames H. TsaiKao-Tai and Nancy TsaiNoel H. TurnerJohn P. UnikMelvin C. VailNikhil and Manisha VaraiyaDavid L. Wagger, Ph.D.Frederick T. WagnerGregory J. WagnerJennifer S. WakitaAlexander K. C. WangBennet M. WangFrancis T. WangHsu-Kun Wang

Stanley WangRobert WaterhouseMark Weidenbaum and Lisa Berke

Robert F. WeimerRobert B. WelchWilliam J. WelchDwight D. WellerPeter H. WendschuhDr. William C. WernauCarolyn A. WesterdahlDavid WhitmoreGina WhitneyJames Thor WilliamsRichard Q. WilliamsPeter B. WilsonThomas and Betty WinfieldStephen F. WolfDaryl B. WongEric K. WongPatrick WongRichard L. C. WongSharon M. WongMabel Lowe WooBarbara A. WoodBenjamin and Nichole WoodKevin D. and Virginia M.Woodburn

J. D. WordieRonald WrightAlbert H. WuBo YangWeidong YangZhen-Yu YangPaul C. J. YehShan J. YehAnissa and Gary YeungKenneth and Nicole YiJackson YuMarsha Yuan and Michael Chaisanguanthum

Petros D. ZavitsanosJenny ZhuZai Xin Zhu and Ya Hua WangRobert D. Zimmerman


38


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The Honor Roll

$1 to $99.

Joselle AbagatMarc J. AdlerKevin L. AlexanderDr. Habib AminPhyllis and Larry AndersonAnonymous (4)David ArnostiZaid A. AstarabadiRobert and Yadja BacherLeif M. BacklundKyoung Y. BaekJoseph K. BaileyStan BarnettEdward M. BarrishGeorge H. BatchelderBrian and Lori BeaudoinDean BenderRonald S. BesserOnita BhattasaliYashodhan BhaweJoleine M. BigcasRichard W. BorryGregory B. BoursalianDale C. BowyerJonathan H. BoyceR. E. BozakMitchell C. BrennerRob BroekhuisSteven BrombergCharles R. BrownHarmon and Elizabeth BrownWilliam H. BrownMark A. BurlingameBruce A. CapronRonald M. CarnJohn W. CarrozAda Woo and Joe CarsonDonald A. CassRobert P. ChambersErik ChandraAngela Y. ChangMary Pin ChangJonathan D. Chapple-SokolJohn J. ChenPei-Shiun ChenYung Cheng

Mr. and Mrs. Thomas J. C.Chew

Mark and Dora ChienGary and Charissa ChockTracey ChowHan S. ChuehJanis K. ChunRobert D. ClayMary E. CliffordJames L. ColeJohn B. Collins, Ph.D.Rosemary M. ConradKyla D. CookVirginia CornishDouglas H. CortezWilliam M. CwirlaSean DabelHoward E. Davis, Jr.Jacob M. DavisColonel Oak H. DeBergAndrew and Carol DeGracaCelicia D. DellaBeatrice A. DimpflJames R. DouglassIrena DragojevicRonald P. DruckerDavid P. DuberowTam Thi Ngoc DuongJohn W. and Marlene JensenEastman

Robert E. and SuzanneEmberton

Kin Eng and Gail Escalona-Eng

Felicia A. EtzkornWinny A. FamWatson FearingH. G. FeatherstonaughA. Edward FennJack FinneyGeorge FitzgeraldGeorge M. FohlenHenry FongErik M. FreerJanet FrickCraig GatesJ. Daniel GezelterEdward GillanMichael D. GillespieGwen M. Ginley

David GlueckAlex GoretskyGail L. GrayMichael L. GreenfieldFrank GreerXun GuJondi GumzKenneth and Carol HamiltonNeil S. HanabusaJohn E. HansonProf. and Mrs. Robert A.Harris

Jennifer A. HartKathleen HengBruce Michael HenkinKay and Theresa HerbertJames and Shih-Min HollandVu P. HongDavid HornerNancy Johnsen Horton andJohn Douglas Horton

Yoko Hsueh ShiraiChae Sim HuangChu Liang HuangCynthia HuangCamden R. HubbardKyung HughSabrina HuynhMary Lee HydeUgonna IhenachoBrian Aki IkkandaJanice S. JavierJonathan N. JaworskiSriharsha JayantiMichael and Elizabeth JellenTiffany JenVivian JiangFranklin and Rose JinBrian JohnstonBerardo JuradoTimothy B. KarpishinNa Young KimMatthew Cameron KinneRoland KoestnerStanley KoshanTawni KoutchesfahaniGeorgina Garbutt KratzerCynthia KriegerFrank B. Krivohlavek

James H. KruegerRomesh KumarDouglas S. KuramotoDenis and Linda KurtY. R. KwanPeggy McMahan LareauJohn F. LathropTsun Yin LauCliff A. LayAmy S. LeeDonald W. LeeMartin and Nailin LeeStacy LeeYoon Sup LeeColin W. LeesAndrew S. LemoffJoshua LeonardWai Man LeongGabriella LestariAnita LeungJason LewisJohn D. LeybaMichelle Kong and Jun LiXue LiThomas and Janet LichtermanConnie LimJin-Ping LimElaina LinGene C. LinJie Hua LinKevin Guangcheng LiuShaoyong and Tong LiuLisa Lobree and Cameron Abrams

Ann L. LongLarry Loomis-PriceThomas J. LoweryEric LuCharles LudvikAlfred LyantoRichard A. MacPhailSussie MahFrank A. MahlerAnil MallyaJoseph J. MarlinHelen and John MatthewsFrank and Catherine McCarthyKaren and Steven McDonaldBarry and Donna McElmurry

annual report ’09

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Glen A. RogersDobbie L. RoisenPeter R. RonyMichael W. RoweSanford A. SafronCleo SalisburyDiane and Andy SantamariaRebecca and Matthew ScheckVinod K. ShahCharlton ShenTae Soo ShinSara and Bakthan SingaramHarmeet SinghSteven W. SintonJames T. SlamaShepard J. SmithlineFerry and Melani SoendjojoAaron Bradley SolinTimothy SpenceSusan StantonSarah G. StewartElise C. StoneBryan StubbertJoel SusskindDebra M. SuzukiJon T. SwansonRobert and Linda SwoffordVazken TashinianGeoffrey A. TheissJoel A. ThorntonTalar TokatlianCharlotte H. TranHenry Hiep TranMichael and Susan TranquillaDale TrowbridgeVictor and Susan TsaiFamily of Margaret M.(Schultz) Tsiang

Michael W. TsiangRicardo UnikelMarijke H. C. Van SpykMathias van ThielPaul VerderberDavid J. VieiraDiana N. VietMary F. VondrakMichael A. WalkerPam Wang

Ken WatermanClayton A. WebbAdam Z. WeberJohn B. Wheeler, Jr.Donald W. Whisenhunt, Jr.Ralph E. WhiteClaire M. WoodburnAdam and Shannon WoolleyCindy Hsin-I WuDavid Tai-Wei WuPei-Hua WuAlexander L. XenakisLei G. XingLiub-Chii Yang ChenLaura YeeRonald YehAlbert Fu-Ding YenGeibao YinKrystine Nichole YuJohn ZelinskyRay R. ZhangJohn and Renate Zinn

Tributes

Gifts have been received inhonor of:

Prof. Paul A. BartlettProf. Robert G. BergmanProf. Harvey W. BlanchMr. Samuel W. CalvertProf. Joseph Cerny, Jr.Dr. Michael D. Grimes, DPMProf. Charles B. HarrisProf. Clayton H. HeathcockProf. Harold S. JohnstonProf. C. Judson KingDr. Deanne C. KrenzProf. Emeritus Scott LynnDean Richard A. MathiesMrs. Camille OlufsonProf. John M. PrausnitzProf. Richard J. SaykallyMrs. Jane L. ScheiberProf. Gabor A. SomorjaiProf. Andrew Streitwieser Jr.

Jonathan McLeodRichard T. MeyerAlbert and Loretta MonacoTerry MoodyKarl T. MuellerSarah MullinsWilliam MurrayMarcel W. NathansRandy P. NeislerNorman T. NelsonCaroline NguyenKristine A. NolinJames and GeorgianaNygaard

Jodie M. NygaardHiroko OhtaniJon and Susan OkadaRobert OllerMarjorie OlsonJacqueline OrbonMorton OrentlicherWilliam H. OrttungBruce W. PagePriya S. ParikhDilworth Y. ParkinsonChristine K. PayneLibbie S. PelterQiQi PengMerritt H. PetersonJoseph P. PhillipsJohn and Judi PohlWilliam Polik and Joanne Stewart

Morgan PonderBing T. PoonPatrick J. PurcellHaibo QiJesse Qi and Jimei TianGuohua Mao and Jie QianChristina L. QuigleyLeila A. G. RanisCraig L. ReederPatrick J. ReillyRonald and Monica ReimerGordon and Sharon RenkesKeith RickertGary E. RitcheyGerald and Maureen RitterGary L. Robison


40

donors to the collegeGifts have been received inmemory of:

Mr. Samuel AbrahamsMr. Eric B. AbramsonDr. Ian R. BartkyMr. E. Morse BlueDr. Benjamin P. C. BoussertDr. Gary E. BrodaleProf. Melvin CalvinAlicia M. CervantesProf. William G. DaubenMr. Peter Di MuroProf. Alan S. FossMr. LeRoy G. GreenProf. William D. GwinnDr. Heinz HeinemannMs. Lina Hirzel-WirzDr. Robert H. IwamotoMs. Margaret JorgensonProf. George JuraDr. Frank Howard KratzerMr. Daniel J. LucasProf. David N. LyonWilliam H. McAdamsProf. Emeritus Donald S.Noyce

Dr. Axel R. OlsonProf. Eugene E. PetersenProf. George C. PimentelProf. Kenneth S. PitzerDr. Paul B. PlouffeProf. Henry RapoportDr. Charles B. RolandDr. Robert ScarboroughDr. Thomas H. SchultzProf. Glenn T. SeaborgDr. Ashraf ShalabyDr. Deepak K. SharmaProf. Mitchel ShenClayton Conner ShepherdMr. George D. SniderMrs. Ann StewartProf. Emeritus Charles W.Tobias

Dr. Himanshu B. VakilMrs. Theodore VermeulenProf. Theodore VermeulenDr. Emil J. Volcheck, Jr.

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annual report ’09

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AlumniAssociationSteering TeamGilbert T. Basbas, B.S. ’04,ChemE

Gordon G. Chu, B.S. ’03,ChemE

Laurie J. Dockter, B.A. ’71,Chem

Dean C. Draemel, B.S. ’70,M.S. ’75, ChemE

Marissa Drouillard, B.S. ’00,Chem

Mark W. Ellsworth, Ph.D. ’93,Chem

Lara A. Gundel, Ph.D. ’75,Chem

Deanne C. Krenz, B.S. ’94,Chem

Lawrence B. Perry, B.S. ’56,ChemE

Daisy Y. Quan, B.S. ’47, ChemSteven F. Sciamanna, B.S. ’79,Ph.D. ’86, ChemE

Lucinda A. Vejar, B.S. ’85,Chem

Rebecca Zuckerman, Ph.D.’00, Chem

Alumni EraVolunteers

The following have volun-teered their time to theAlumni Association’s “eragroups.”

G. N. LEWIS ERA: 1945 ANDEARLIER

G. Douglas Gould, B.S. ’42Chem

CUPOLA ERA: 1946-1963

Frank G. Delfino, B.S. ’51ChemE

E. Kenneth Hulet, Ph.D. ’53Chem

David N. Lyon, Ph.D. ’48Chem

Mary F. Singleton, M.S. ’59Chem

volunteerscollege advisory boardJohn H. AbelesMedVest Inc.

William BanholzerThe Dow Chemical Company

Paul F. BryanPh.D. ’85, ChemEChevron Technology Ventures

Sunney I. ChanB.S. ’57, ChemE; Ph.D. ’61, ChemCaltech (emeritus)

Nirmal ChatterjeeM.S. ’68, Ph.D. ’71, ChemEAir Products and Chemicals, Inc.(retired)

Carl P. DeciccoBristol-Myers Squibb

Sam H. EletrPh.D. ’68, ChemPopulation Genetics

Stephen P. FodorPost-doc ’91, ChemAffymetrix Inc.

Richard A. GottschoLam Research Corporation

Christopher A. HaskellBayer HealthCare Pharmaceuticals

Victoria F. HaynesB.A. ’69, ChemRTI International

Herbert H. HooperPh.D. ’90, ChemEAmpersand Ventures

F. Emil JacobsExxonMobil Research andEngineering Company

M. Ross JohnsonPostdoc ’71, ChemParion Sciences, Inc.

Yuan T. LeePh.D. ’65, ChemAcademia Sinica and UC Berkeley(emeritus)

Richard A. LernerScripps Research Institute

John H. MarkelsPh.D. ’93, ChemEMerck & Company

Gary M. MasadaB.A. ’66, ChemChevron Corporation (retired)

Alan MendelsonLatham & Watkins, LLP

Terry J. RosenPh.D. ’85, ChemAmgen

Charles V. ShankUC Berkeley, LBNL (emeritus)

Darlene SolomonAgilent Technologies

James A. TrainhamB.S. ’73, Ph.D. ’79, ChemESundrop Fuels, Inc.

R. Stanley WilliamsM.S. ’76, Ph.D. ’78, ChemHewlett-Packard Company

Steven D. YoungPh.D. ’82, ChemMerck Research Laboratories

Sheila W. Yeh, B.S. ’80, Ph.D.’85, Chem

YOUNG ALUMNI: 2000 ANDBEYOND

Stephen Chan, B.S. ’01 ChemEMarissa Drouillard, B.S. ’00Chem

Rebecca Zuckerman, Ph.D.’00 Chem

FundraisingVolunteers

The following assisted theCollege in fundraisingefforts in 2008–2009.

Keith Alexander, B.S. ’78,Ph.D. ’83, ChemE

John Brauman, Ph.D. ’63,Chem

J. Peter Clark, Ph.D. ’68,ChemE

Dean C. Draemel, B.S. ’70,M.S. ’75, ChemE

Tarric El-Sayed, Ph.D. ’87,ChemE

John Hecht, Ph.D. ’99,ChemE

Joon S. Moon, Ph.D. ’64,ChemE

Curtis Munson, B.S. ’76,Ph.D. ’85, ChemE

Janet Tamada, Ph.D. ’89,ChemE

Rodney Thompson, Ph.D. ’86,ChemE

Bill Young, Ph.D. ’67, Chem

THE FREE RADICALS: 1964–1979

Laurie J. Dockter, B.A. ’71 ChemRobert P. Hohmann, B.S. ’78ChemE

Curtis L. Munson, B.S. ’76,Ph.D. ’85 ChemE

Carolyn M. Orelli, B.S. ’70Chem

Steven F. Sciamanna, B.S. ’79,Ph.D. ’86 ChemE

Bruce E. Stangeland, Ph.D. ’67ChemE

THE CHEMILLENNIUMS:1980–1999

Marilee M. Brooks, M.S. ’88ChemE

Paul V. Burke, B.S. ’81 ChemEGrace F. Chou, Ph.D. ’88ChemE

Daisy J. Du Bois, Ph.D. ’94Chem

Mark W. Ellsworth, Ph.D. ’93Chem

Maria S. Fardis, Ph.D. ’98Chem

Thomas R. Gadek, Ph.D. ’86Chem

Deanne C. Krenz, B.S. ’94Chem

Susan M. Miller, Ph.D. ’83Chem

Walter H. Moos, Ph.D. ’82Chem

Alyssa L. Roche, B.S. ’87ChemE

Steven F. Sciamanna, B.S. ’79,Ph.D. ’86, ChemE

Michael M. H. Yang, B.S. ’92Chem & ChemE

Dean (B.S. ’70,M.S. ’75, ChemE)and BeckyDraemel enjoythe Dean’sDinner, heldannually at TheFaculty Club.

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Industrial FriendsProgram

Membership in the Collegeof Chemistry IndustrialFriends Program is open toany firm, regardless of size orlocation. Annual support of$25,000 or more can comein the form of unrestrictedfunds, departmental fellow-ship funds, start-up fundsfor non-tenured faculty, sup-port for facilities or researchfunds for tenured faculty.

3MAbbott LaboratoriesAgilent TechnologiesAir Products and ChemicalsAmgen, Inc.Arkema, Inc.AstraZenecaBayer HealthcarePharmaceuticals

Bristol-Myers SquibbCanon Inc.Chevron CorporationCrystalGenomicsDow Chemical CompanyDuPontEli Lilly and CompanyGeneral Motors CorpGenentech, Inc.Gilead SciencesGlaxoSmithKlineHitachiHonda R&D Americas, Inc.Johnson & JohnsonLam Research CorporationMerck & CompanyNovartis, Inc.

Procter & Gamble CompanyRobert Bosch CorporationRoche Palo AltoRohm and Haas CompanySchlumbergerShowa Denko K. K.SpectraWattToyobo America, Inc.Tyco Electronics

Gifts of $100,000and moreAmerican Cancer SocietyAgilent TechnologiesAmgen, Inc.Bristol-Myers SquibbCamille and Henry DreyfusFoundation

Dow Chemical CompanyGilead SciencesLam Research CorporationNovartis, Inc.Q-ChemRoche Palo Alto

Gifts of $50,000 to$99,000Abbott LaboratoriesAstraZenecaChevron CorporationDuPontEli Lilly and CompanyGenentech Inc.HitachiHonda R&D Americas Inc.Robert Bosch Corporation

SpectraWattTyco Electronics

Gifts of $25,000 to$49,000American Chemical Society,Division of OrganicChemistry

Arkema Inc.CrystalGenomicsMerck & CompanySchlumbergerShowa Denko K. K.Toyobo America, Inc.

Gifts up to $24,999American Chemical Society,Division of MedicinalChemistry

Bayer HealthcarePharmaceuticals

Centre Europeen de CalculAtomique et Moleculaire

Clorox CompanyDaiichi-Sankyo Co. Ltd.Dainippon Sumitomo PharmaCo, Ltd.

Eastman Chemical CompanyExxonMobilGenencor, A Danisco DivisionGiauque Scientific Papers Fdn.GlaxoSmithKlineIntel CorporationJSR CorporationKLA Tencor CorporationNewry Corp.Organic Syntheses, Inc.

Pfizer, Inc.PowervisionProcter & Gamble CompanyRohm and Haas CompanyRoyal Society of ChemistryTakasago InternationalCorporation

U.S. Civilian Research &Development Foundation

Matching Gifts3M Foundation, Inc.AccentureAgilent TechnologiesAir Products and Chemicals,Inc.

Altria Inc.Applera Corp. BASF CorporationBaxter HealthcareBeckman Coulter Bridgestone/Firestone TrustFund

Bristol-Myers SquibbCBI FoundationChevron CorporationCiscoClorox Company FoundationConocoPhillipsDow Chemical USAEli Lilly & CompanyEsterline Technologies C0rp.ExxonMobil FoundationFair IsaacFidelity FoundationGenencorGenentechGeneral Electric FoundationGeneral Motors Foundation


42

corporate, foundation andorganizational gifts It is our pleasure to acknowledge the

many companies and other organizations that continue to invest in the college’s future. These

donations represent a major source of funding for our graduate, research and teaching programs.

Contributions for 2008–09 are listed below.

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GlaxoSmithKlineHess CorporationHospiraIBM CorporationIFF FoundationIntel FoundationJohnson Controls FoundationLam Research Corp.Lockheed MartinLubrizol

Lyondell Chemical Co.MedtronicMenasha Corp FoundationMerckMicrosoftMillipore FoundationMonsanto FundMRW & AssociatesNorthrop Grumman CorpOSIsoft

Pacific Gas & ElectricPepsiCoPfizer Inc.Pharmacia & UpjohnFoundation

Pioneer Hi-Bred InternationalPNM FoundationProcter & Gamble FundRaytheon Company

Science Applications Int’l.Shell Oil Company FoundationSun MicrosystemsTakedaTektronix FoundationValero Energy CorporationWashington Group FoundationWells FargoWyeth (American Home Products)

annual report ’09

(rear, l. to r.) Chevron’s Rebecca Brafman (B.S. ’00, ChemE), ChemEchair Jeff Reimer and Chevron’s Alyssa Roche (B.S. ’87, ChemE)pose with the winners of the Chevron Scholarship in ChemicalEngineering, (front, l. to r.) Cindy Xu, Liliana de la Paz and Fei Chu.

Dean Richard Mathies presents Steve Lindsay of Lam Research witha plaque to express Berkeley’s gratitude for a generous gift to set upa Lam Research Chair in Semiconductor Processing. (l. to r.) Prof.Tsu-Jae King Liu, Jeff Marks, Dean Richard Mathies, DraganPodlesnik, Steve Lindsay, Mark Retzer, Prof. David Graves, TamaraCroyts, Shail Kumar, Dave Hemker.

Bob Lamoreaux, instructional support manager for the College ofChemistry, inspects equipment and software given by AgilentTechnologies with Chris Hahn, a graduate student instructor inChem 4 and member of Professor Peidong Yang’s research group.

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ad B th in co


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forms of givingbenefits for the college—and for the donors

Many different kinds of gifts can benefit bothyou and the University. Some of them canoffer particular estate planning advantages,including income for life. Our professionalstaff would be pleased to discuss these giftvehicles with you; however, the Universityurges you also to consult your attorney orfinancial advisor.

If you wish your gift to benefit the college,any legal documents or instructions shouldspecify that the gift is for the College ofChemistry (or the Department of Chemistryor the Department of Chemical Engineering)at the University of California, Berkeley.

CA SH Checks should be made payable to the UC Berkeley Foundation (UCBF),with a notation designating the name ofthe fund. Gifts to memorial funds shouldbe made payable to the specific fund.Contributions may also be made with your Visa or MasterCard credit card byphone (510/642.9506), or online at givetocal.berkeley.edu/chem/.

S ECUR I T I E S In most cases, gifts ofappreciated securities may be deducted atfull market value as of the date you makethe gift, and the donor does not have to paycapital gains taxes. Gifts of appreciatedstock are most easily handled by the UCBerkeley Foundation and should not be soldprior to transfer. You or your broker maycontact Acting Assistant Dean Mindy Rexin the college (510/642.9506) or Ms. SylviaWorthington, Securities Steward inUniversity Relations (510/642.4123), for

further information. Stock can often betransferred electronically. If you wish togive a gift of depreciated stock, you shouldfirst sell it and give the proceeds to theFoundation. You can then use the loss tooffset any gains and also claim a charitablededuction.

R EA L E S TAT E Gifts of real property maybe deeded to UC Berkeley for the benefit ofthe College of Chemistry, providing signifi-cant tax advantages to the donor in mostcases. It is also possible to deed a propertyto the University and continue to occupy itfor life.

L I F E I NCOME G I F T S A number ofoptions are available by which you maytransfer assets to a trust (to be managedeither by the University or a trustee of yourchoosing) and receive income for yourselfand/or a designated beneficiary for life, aswell as immediate tax benefits. The collegeultimately receives the trust property.

B EQUES T S A fixed amount or a per-centage of your estate may be designatedfor the benefit of the College of Chemistryin your will or living trust.

MATCH ING G I F T S Hundreds offirms match their employees’ (and some-times retirees’) contributions on a 1:1, 2:1or even 3:1 basis. If your company has sucha policy, forms—hard copy or electronic—to assure that your gift will be matched can be obtained from your personnel oremployee relations office. Matching giftsare added to your individual gift in determining the donor club to which you belong.

giving to the college of chemistry

college fundsTHE ANNUAL FUND provides essen-tial monies that can be used, at the discretionof the dean or of the chairs, to meet needsthat are not supported by the state budget.These unrestricted funds are particularlyvaluable because of their flexibility. Theannual fund is vital for financing ongoingprograms and special projects.

ENDOWED FUNDS provide a perma-nent source of income to meet the needsof faculty and students in perpetuity.

MEMOR I A L FUNDS commemorateindividuals while benefiting the collegeand the departments of chemistry andchemical engineering. Donations may also be given to the annual fund in memory or in honor of an individual,and the college will notify the family that a contribution has been made.

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archive

In a five-page letter to NASAadministrator John E. Naugle, dated January 16, 1968,Berkeley chemistry professor George Pimentel defendsthe group of young researchers building the Marinerinfrared spectrometer and argues for the necessity of thecontributions of outside scientists to NASA missions.

THE REPORT OF PRIVATE GIVINGCOLLEGE OF CHEMISTRY 2008–2009

The preceding report acknowledges all donors to the College of Chemistryfrom July 1, 2008 through June 30,2009. We have made every attempt to include all donors accurately. We apologize for any errors or omissionsand would appreciate hearing fromyou with any comments or correctionsregarding this publication.

acting assistant deanMindy Rex

director of annual giving and corporate and foundation relations

Nancy Johnsen Horton

director of alumni relationsCamille Olufson

development services managerDorothy Isaacson Read

For further information about giving to theCollege of Chemistry, please contact

College Relations and DevelopmentCollege of Chemistry #1460University of California, BerkeleyBerkeley, CA 94720-1460Phone: 510/642.9506Fax: 510/642.4419Email: [email protected]

15574_1.28_45_Layout 1 12/9/09 1:09 PM Page 45

Catalystuniversity of california berkeleyCollege of Chemistry420 latimer hall #1460berkeley, ca 94720-1460

Upcoming 2010 Alumni Events

Cupola Era Alumni Luncheon Date TBA Watch for a separate mailing in late January/early

February for the Cupola Era alumni event. This eraincludes friends and alumni from the graduating years1946–63.

Cal DayApril 17 This annual campus-wide open house has some-

thing for everyone! As the date draws closer, checkout berkeley.edu/calday for the complete listing ofevents and programs.

SpringfestApril 29 6:00–7:30 p.m.

Jupiter Beerhouse, 2181 Shattuck Ave. BerkeleyWe hope that you will join us as we celebrate our 2010graduating undergraduate and graduate students! Asthe time approaches, check out our homepage at chem-istry.berkeley.edu/alumni/events.html for more details.This is a complimentary event, and reservations are notrequired.

Nanotechnology ForumsDate TBA Berkeley Nanotechnology Forum

The Berkeley Nanotechnology Forum 2010 (BNF 2010)features leading scientists, entrepreneurs and academ-ics presenting their views on the current achievementsand future opportunities in the field of nanotechnology.For more information, visit nanoclub.berkeley.edu.

Upcoming Seminars and LecturesGo to the College of Chemistry’s website atchemistry.berkeley.edu and select Seminars and Eventsto view the college’s seminar calendar.

+ For alumni events, visit chemistry.berkeley.edu/alumni/events.html

background image: rayograph courtesy of michelle douskey

nonprofit org.u.s. postage paiduniversity of california

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catalyst magazine v 4.2

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