case testimony of the participation of one particular laboratory to the european research programmes...
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Case Testimony of the Participation of One Particular Laboratory
to the European Research Programmes in Life Sciences (4th and 5th Frameworks)
Prof. Dr. ir. Jean Swings
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1. Laboratory of Microbiology at Ghent University • Research group • BCCM/LMG Bacteria Collection
2. Projects in the 4th and 5th EU Research Framework • Projects and research teams • Life of a project • Outputs and excitements • Our Italian partners
3. Difficulties & Frustrations4. How to proceed in the 6th Framework ?
Overview
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Laboratory of MicrobiologyLaboratory of MicrobiologyGhent UniversityGhent University
http://lmg.rug.ac.be
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GHENT UNIVERSITY - FACULTY OF SCIENCESGHENT UNIVERSITY - FACULTY OF SCIENCESLABORATORY OF MICROBIOLOGYLABORATORY OF MICROBIOLOGY
RESEARCH GROUPS
TEACHINGTEACHING UNIVERSITY STUDENTS IN BIOLOGY, BIOTECHNOLOGY, BIOCHEMISTRY
RESEARCHRESEARCH on CLASSIFICATION, PHYLOGENY, IDENTIFICATION AND TYPING OF BACTERIA, related to ECOLOGY, BIODIVERSITY,
BIOTECHNOLOGY • Rhizosphere bacteria (N2-fixers), plant pathogenic bacteria
• Bacillus and allied groups • Lactic acid bacteria (probiotics) • Drinking water systems • Antarctic mats, fresh waters, tropical soils • Biodegradation of bioplastics, xenobiotics • Horizontal gene transfer • Bacteria from clinical, veterinary and industrial environments
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GHENT UNIVERSITY - FACULTY OF SCIENCESGHENT UNIVERSITY - FACULTY OF SCIENCESLABORATORY OF MICROBIOLOGYLABORATORY OF MICROBIOLOGY
BCCM™/LMG BACTERIA COLLECTION
PRESERVATIONPRESERVATION and DISTRIBUTIONDISTRIBUTION of BACTERIAL CULTURES
SERVICESSERVICES
RESEARCHRESEARCH • Taxonomy, phylogeny, classification, identification and typing of bacteria from clinical, veterinary and industrial environments • Data mining • Standardization, automation / robotisation • Quality control
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GHENT UNIVERSITY - FACULTY OF SCIENCESGHENT UNIVERSITY - FACULTY OF SCIENCESLABORATORY OF MICROBIOLOGYLABORATORY OF MICROBIOLOGY
The BCCM™/LMG BACTERIA CULTURE COLLECTIONBACTERIA CULTURE COLLECTION
holds holds 20.000 named strains, 20.000 named strains, representing 1.800 species :representing 1.800 species :
Plant pathogenic or plant associated bacteriaPlant pathogenic or plant associated bacteria
Bacteria of medical or veterinary importanceBacteria of medical or veterinary importance
Bacteria of marine originBacteria of marine origin
Various groups of potential biotechnological interestVarious groups of potential biotechnological interest
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Programme Participating countries Runningtime
Topic
ECLAIR B, UK, D 01/90-12/93 Bacterial polyester plasticsFAR EL, B, E 02/91-01/93 Hatcheries for mediterranean marine fishAIR B, UK, F, DK, E, S 11/92-03/96 Fish pathogenic VibrioENV B, S, I, D 02/93-01/95 Physical weathering and bioreceptivity study on building
stonesHCM-NW D, B, F, UK, NL, E 12/93-11/95 Microbiological diversity networkAIR B, D, CH, I 12/93-01/97 Biodegradability of bioplasticsAIR EL, B, S 04/94-03/97 Hygiene and disease prevention in fish larvicultureSTD3 B, CN, UK, EC 06/94-05/97 Bacterial diseases in penaeid shrimp hatcheriesINTAS B, D, RU, UA 06/95-06/96
04/97-03/98Microbiology of objects of cultural heritage and art
FAIR IRL, UK, B 02/97-10/99 Risk assessment of antimicrobial agent use in aquacultureFAIR EL, NL, D, B, I, IRL 09/97-08/00 Enterococci in food fermentationsINCO-DC D, B, MA, TR 12/97-06/01 Drinking water treatment for nitrate and pesticide removalINCO-DC B, UK, BR, CL 01/98-12/00 Improvement of scallop production in rural areasE&C D, E, A, B 04/98-03/00 Microbial communities of mural paintingsFAIR D, B, CH, I 06/98-05/01 Biopolymer-natural fibre-compositesBIOTECH B, D, NL, UK, I, F, E 11/98-10/00 Biodiversity of microbial mats in AntarcticaEVK E, AU, B, FIN, D, I 01/00-12/03 Molecular microbiology as conservation strategy for cultural
assetsQOL IRL, A, F, UK, B, D 09/01-08/04 Anti-listerial activity of microbial consortia from cheese.INCO-DEV UK, B, VN, MY, TH, I 01/02-12/04 Antimicrobial resistance associated with Asian aquacultureQOL B, D, F, NL 01/02-12/05 Biosafety of probiotic lactic acid bacteria for consumption
Projects in the 4th and 5th EU Research Frameworks
20 projects with partners from 25 countries
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“Micro-organisms are everywhere”
• Antibiotic resistance• Probiotics• Microflora of cheeses• New bioactive compounds from Antarctic micro-organisms• Aquaculture related microbiological problems• Bioplastics and biodegradable composites• Microbiological characterization of drinking water systems• Biodeterioration of cultural heritage
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Setting up a EU project was the most exciting part of it, particularly as a coordinator
The initial enthousiasm was very inspiring
Project Life
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Project Life
waiting for evaluation results
project execution
prep
arat
ion
final reportspublicationsother output
5-6 years
meetings
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• Kick-off meetings : always euphoric, not to be underestimated• Project meetings (+extra meetings)• Reports• Exchanges of scientists / technicians• Scientific successes & failures• Publications and presentations• New ideas —> new contacts —> new proposals
Project Life
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In total the Laboratory of Microbiology, RUG has secured :
from EU Frameworks 4 and 5 programmes
over 3’000’000 euro
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Publications (total LMG)Publications (total LMG)
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Project publications
0123456789
1011
1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001
Projects runningPublications
>50 in peer reviewed international journals
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Succession of projects : an example on bioplastics
ECLAIRBacterial polyester plastics
1990-1993
AIRBiodegradability testing of bioplastics
1993-1997
FAIRBiocomposites
1998-2001
INCODrinking water treatment using bioplastics
1997-2001
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The end of the project
• Final report• Publications• Human contacts often remain• Other outputs:
- collections of micro-organisms- databases (sequences, properties)- PhD theses
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Excitements
• Planning phase• Approval• Kick-off• Exchange of materials• Putting together the data (puzzle)• Publishing together• Meeting again at other occasions
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Other positive sides
• Involvement and training of PhD students & postdocs• Personal contacts• Interdisciplinarity as a professional enrichment• Deepening of own expertise• Requirement to collaborate and communicate• My participation in the EU evaluation panel on projects, thematic networks & mobility was a very positive experience
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Our Italian Partners
Programme Organization City Main contactENV University Trieste L. NimisAIR, FAIR University Bologna M. ScandolaFAIR Company Orbassano A. PipinoFAIR University Verona F. DellaglioFAIR Company Busche d.C. B. AttorniFAIR Research institute Thiene A. LombardiBiotech Company Gerenzano F. MarinelliEVK University Messina C. UrziINCO Company Genova B. Bertone
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We greatly appreciate our Italian partners for :
• scientific excellence
• trustworthiness
• enthousiasm
• loyalty
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Difficulties
Several difficulties arose during the execution of some projects, with the coordinator, with the other partners, others (industrial partners, EU), e.g.
• important cuts in the budget• coordinator got ill, was replaced only after months• coordinator was not coordinating• participants doing less than promised• late reports (and thus late reimbursement of costs)
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Frustrations
1. The unacceptable low success rate upon application: so many excellent proposals were turned down
2. Scientists need more flexibility to deal with the scientific problems that arose, but also with the coordination and management problems
3. Unsolved aspects, e.g. how to deal with :• intellectual proprietary rights• companies or SME’s• the aftermath of a project
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Conclusions
1. EU projects were a EU success story
2. The participation in EU projects is seen as a proof of quality of the research group
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And now … to the heart of the matter:
How to proceed in the 6th Framework ?