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    Case report : Gastroenteritis

    PRESENTED BY

    ADE IRMA 070100054

    SRI WAHYUNI 070100076

    SUPERVISOR : Prof. dr. Atan Baas Sinuhaji, Sp.A(K)

    PEDIATRIC DEPARTEMENT

    HAJI ADAM MALIK GENERAL HOSPITAL2011

    1

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    Definition Gastroenteritis

    Diarrhoea is the passage of unusually loose or

    watery stools, usually at least three times in a

    24 hour period. However, it is the consistency

    of the stools rather than the number that is

    most important. Frequent passing of formed

    stools is not diarrhoea (WHO, 2005).

    2

    WHO. The Treatment of Diarrhoea: a Manual for Physicians and Other Senior Health

    Workers 2005.

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    Epidemiology

    3Farthing et al. Acute Diarrhea. World Gastroenterology Organisation, 2008;

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    Inverse association between coverage rates of oral rehydration

    solution (ORS) use and rates of mortality from diarrhoea in

    various countries.

    4Farthing et al. Acute Diarrhea. World Gastroenterology Organisation, 2008;

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    Etiology

    Causes of diarrhoea with acute onset includethe following:

    Infections

    Drug-induced

    Food allergies or intolerances

    Disorders of digestive/absorptive processes

    Chemotherapy or radiation-induced enteritis

    Vitamin deficienciesGuandalini S. Diarrhea. Available from: http://emedicine.medscape.com/article/928598-followup[Accesed 23

    February 2011].

    5

    http://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followup
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    Infectious causes of acute diarrhoea in

    developed countries

    Viruses

    Rotavirus - 25-40% ofcases

    Norovirus - 10-20% of

    cases Calicivirus - 1-20% of

    cases

    Astrovirus - 4-9% ofcases

    Enteric-type adenovirus -2-4% of cases

    Bacteria

    Campylobacter jejuni - 6-8% of cases

    Salmonella - 3-7% of

    cases E Coli - 3-5% of cases

    Shigella - 0-3% of cases

    Y enterocolitica - 1-2% ofcases

    C difficile - 0-2% of cases

    Vibrio parahaemolyticus -

    0-1% of cases V cholerae - Unknown

    Aeromonas hydrophila -0-2% of cases

    Parasites

    Cryptosporidium - 1-3% of cases

    G lamblia - 1-3% ofcases

    6Guandalini S. Diarrhea. Available from: http://emedicine.medscape.com/article/928598-followup [Accesed 23 February 2011].

    http://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followup
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    Classification

    which lasts several hours or days: the main danger is dehydration;weight loss also occurs if feeding is not continued;

    Acute watery diarrhoea (including cholera)

    Bloody and mucous present. The main dangers are damage of theintestinal mucosa, sepsis and malnutrition

    Acute bloody diarrhoea (Dysentry )

    which lasts 14 days or longer

    Persistent Diarrhoea

    Main dangers are severe systemic infection, dehydration, heart failureand vitamin and mineral deficiency

    Diarrhoea with severe malnutrition (marasmus orkwashiorkor):

    7

    WHO. The Treatment of Diarrhoea: a Manual for Physicians and Other Senior Health Workers.2005.

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    Feces from humans or animals containing pathogenic microbes

    or their toxins

    food fluids fingers

    Ingestion of organism and/ or toxin

    Organisms multiply and toxinproduced but infection remain in GI

    tract

    Organism invade or toxins absorbed

    dissemination

    Symptoms ofsystemic

    infection ex.

    Fever etc.

    DIARE

    Pathogenesis of diarrhoea 8

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    Pathophysiology

    9

    Silbernagl S and Lang F. Color Atlas of Pathophysiology. New York: Thieme, 2009;

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    10https://reader009.{domain}/reader009/html5/0426/5ae1c46babdad/5ae1c472cad85.png

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    Diagnosis

    History : askpresence of blood in the

    stool; duration of diarrhea; number of

    watery stools per day; number ofepisodes of vomiting etc.

    Physical examination: look and feel

    Take temperature

    11

    WHO. The Treatment of Diarrhoea: a Manual for Physicians and Other Senior Health Workers

    2005.

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    Look and Feel

    12WHO. The Treatment of Diarrhoea: a Manual for Physicians and Other

    Senior Health Workers 2005.

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    Laboratory

    Completeblood count

    Electrolyte Anal swabCulture

    stool

    Immuno

    assay

    13

    Guandalini S. Diarrhea. Available from: http://emedicine.medscape.com/article/928598-followup [Accesed 23

    February 2011].

    http://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followup
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    Differential Diagnose

    Appendicitis

    Intussuception

    Crohn disease

    Irritable bowel syndrome

    14

    Guandalini S. Diarrhea. Available from: http://emedicine.medscape.com/article/928598-followup [Accesed 23 February 2011].

    http://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followuphttp://emedicine.medscape.com/article/928598-followup
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    Treatment

    ORS, iv infusionZn

    Nutrition

    Vitamin A

    Antibiotic

    Probiotic

    15WHO. The Treatment of Diarrhoea: a Manual for Physicians and Other Senior HealthWorkers.2005.

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    16

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    17

    Ionic composition of intravenous infusion solutions

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    Prevention

    Water, sanitation, and hygiene:

    Safe food:

    Cooking eliminates most pathogens from foods

    Exclusive breastfeeding for infants

    Weaning foods are vehicles of enteric infection.

    Micronutrient supplementation: the effectiveness

    of this depends on the childs overall immunologic

    and nutritional state; further research is needed.

    vaccines

    18Farthing et al. Acute Diarrhea. World Gastroenterology Organisation, 2008;

    CASE REPORT

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    CASE REPORT

    19

    7-months-old girl

    (BW: 7kg & BH: 70cm)

    February 13th 2011

    diarrhea

    Since 3 days ago

    The frequency is 10times in a day

    The volume glass

    every time diarrheaIn feces the water ismore than the dregs

    Mucus (+)

    Blood (+)

    Vomitiing

    The frequency is 3times in a day

    The volume 20 ccfor each time

    vomiting

    the contents ofvomite is that what

    she ate and drank

    Fever

    Since since oneweek ago

    high temperature

    Fever lowered with

    antipyretic

    Seizure (-)

    shiver (-)

    recurrent fever (+)since birth

    Wormsinfection

    Weight loss (+)

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    20

    Patient was born spontaneously

    aided by a midwife

    cried immediately at birth

    Cyanosis (-)

    History of birth

    fever (-), hypertension (-), diabetes mellitus(-),drugs(-)

    used the herbal medicine while two monthspregnancy (used for abortion)

    Patient is the fifth child

    mother age is 32 years old

    History ofmaternal

    conditions

    0-2 months : Breast feed and cow milk 2 monthsnow : breast feed, cow milk and

    porridgeAte history

    BCG (+), Polio (three times), Hepatitis B (two

    times), DPT (two times).

    History of

    immunization

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    PHYSICAL EXAMINATION

    Generalized Status:

    Body weight : 7 kg

    Body height : 70 cm

    BW/ BH : 82,3% (mild malnutrition)

    Sensorium : Compos Mentis Body Temperature: 38,2 oC

    Anemic (-)

    Icteric (-)

    Cyanotic (-)

    Oedem (-)

    Dyspnoe (-)

    21

    Light reflexes (+/+)

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    22

    Light reflexes (+/+)

    Isochoric pupiloric,

    pale on inferior palpebrals conjunctival (-/-)

    sunken eyes (+)

    Examination of the ear, mouth and nose cannotbe found any abnormalities.

    Head

    Lymph node enlargement (-)Neck symmetrical fusiform.

    Heart rate was 132 bpm, regular, murmur (-)

    Respiratory rate 40 tpm regular, ronchi (-)

    Chest Soft and tenderness,

    peristaltic was increased

    the liver and spleen was unpalpable,

    turgor slow to return.Abdominal

    Pulse was 132 bpm, regular, pressure andvolume were normal

    acral was warm.

    Blood pressure was 90/60 mmHg

    Extremities

    Female. No abnormalitiesUrogenital

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    Working Diangnosis

    Gastroenteritis with mild-moderate

    dehydration.

    23

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    Management

    IVFD RL 75cc/kgBB/4hours 130 cc 130

    gtt/i micro

    Paracetamol 3 x 100 mg (pulv)

    Breast feed + porridge diet of 700 ccal with 96

    gram of protein

    24

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    Investigation Plan

    Complete Blood Count

    Electrolit

    Ad random glucoseRenal function test

    Liver function test

    25

    L b t i Fi di (D b 13th 2010) f P t l Cli i

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    Laboratorium Findings (December 13th 2010) from Patology Clinic

    Adam Malik General Hospital

    26

    Test

    Result Normal Value

    Hemoglobin (Hb)

    Erytrocyes (RBC)

    Leucocytes (WBC)

    Hematocrit

    Thrombocyte (PLT)

    MCV

    MCH

    MCHC

    RDW

    Complete Blood Count

    10.50 g%

    4.82 x 106/mm3

    11.00 x 103/ mm3

    33.20 %

    456 x 103/ mm3

    68.80 fL

    21.80 pg

    31.70 g%

    15.70 %

    11.1-14.4

    3.71-4.25

    6.0-17.5

    35-41

    217-497

    82-100

    24-30

    28-32

    14.9-18.7

    Neutrophil

    Lymphocyte

    Monocyte

    Eosinophil

    Basophil

    Cell Count

    37.80 %

    47.10 %

    12.90 %

    0.12 %

    2.040 %

    37-80

    20-40

    2-8

    1-6

    0-1

    Sodium

    Potassium

    Chloride

    Ad random glucose

    Electrolit

    133

    3,4

    90

    Carbohydrate metabolism

    104.00 mg\dl

    135-155

    3.6-5.5

    96-106

    < 200

    Follow Up Date 14/2/2011

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    Follow Up Date 14/2/2011

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    S : Diarrhea (+), the frequency is 7 times in a day, in feces the water is more than the

    dregs

    O: Consciousness: Compos Mentis T: 37.7oC, BW: 7kg, BH: 70cm, BW/ BH: 82,3%

    Head : Eyes: Light reflexes (+/+), isochoric pupil, pale inferior palpebralsconjunctiva (-/-), Ears and Nose: no, Mouth: dry mouth (+)

    Neck : Lymph node enlargement (-)

    Chest : Symmetrical fusiformic, retraction (-),

    HR: 126 bpm, regular, murmur (-)

    RR: 38 tpm, regular, ronchi(-).

    Abdomen : Soft and terderness, normal peristaltic. No liver and spleen enlargement.

    Extremities : Pulse 126 bpm, regular, Pressure/Volume: adequate, warm acral

    BP: 90/60 mmHg

    Urogenital : Female, no abnormalitites

    A: Gastroenteritis without dehydration.

    P : IVFD D5% NaCl 0.225%: 30 gtt/i microParacetamol 3 x100 mg (pulv)

    porridge 700 ccal with 14 gram of protein

    Follow Up Date 15/2/2011

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    Follow Up Date 15/2/2011

    28

    S : Diarrhea (+), the frequency is 3 times in a day, the volume 20 cc everytime

    diarrhea , in feces the water is more than the dregs

    O: Consciousness: Compos Mentis T: 36.8oC, BW: 8kg, BH: 70cm, BW/ BH: 94.12%

    Head : Eyes: Light reflexes(+/+), isochoric pupil, pale inferior palpebrals

    conjunctiva (-/-), Ears, Nose, Mouth: no abnormalities

    Neck : Lymph node enlargement (-)

    Chest : Symmetrical fusiformic, retraction (-),

    HR: 140 bpm, regular, murmur (-)

    RR: 4 tpm, regular, ronchi(-).

    Abdomen : Soft and terderness, normal peristaltic. No liver and spleen enlargement.Extremities : Pulse 140 bpm, regular, Pressure/Volume: adequate, warm acral,

    BP: 90/60 mmHg

    Urogenital : Female, no abnormalitites

    A: Gastroenteritis without dehydration.

    P : IVFD D5% NaCl 0.225%: 30 gtt/i microParacetamol 3 x100 mg (pulv)

    Zink 1x20 mg

    porridge 700 ccal with 14 gram of protein

    Follow Up Date 16/2/2011

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    Follow Up Date 16/2/2011

    29

    S : Diarrhea (+), the frequency is 4 times in a day, the volume 20 cc everytime

    diarrhea , in feces the water is more than the dregs

    O: Consciousness: Compos Mentis T: 37.4oC, BW: 8kg, BH: 70cm, BW/ BH: 94.12%

    Head : Eyes: Light reflexes(+/+), isochoric pupil, pale inferior palpebrals

    conjunctiva (-/-), sunken eyes (-), Ears and Nose: no abnormalities,

    Mouth: dry mouth (+)

    Neck : Lymph node enlargement (-)

    Chest : Symmetrical fusiformic, retraction (-),

    HR: 132 bpm, regular, murmur (-)

    RR: 52 tpm, regular, ronchi(-).Abdomen : Soft and terderness, normal peristaltic. No liver and spleen enlargement.

    Turgor fast return (+)

    Extremities : Pulse 132 bpm, regular, Pressure/Volume: adequate, warm acral,

    BP: 100/60 mmHg

    Urogenital : Female, no abnormalititesA: Gastroenteritis without dehydration.

    P : IVFD D5% NaCl 0.225%: 30 gtt/i micro

    Paracetamol 3 x100 mg (pulv)

    Zink 1x20 mg

    porridge 700 ccal with 14 gram of protein

    Oralit 50-100 cc/each time diarrhea

    Follow Up Date 17/2/2011

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    Follow Up Date 17/2/2011

    30

    S : Diarrhea (+), the frequency is 4 times in a day, in feces the water and dregs were the

    same, mucus (+), blood (-).

    O: Consciousness: Compos Mentis T: 38oC, BW: 8kg, BH: 70cm, BW/ BH: 94.12%

    Head : Eyes: Light reflexes(+/+), isochoric pupil, pale inferior palpebrals

    conjunctiva (-/-), sunken eyes (-), tears (+). Ears, Nose, and Mouth: no

    abnormalities

    Neck : Lymph node enlargement (-)

    Chest : Symmetrical fusiformic, retraction (-),

    HR: 152 bpm, regular, murmur (-)

    RR: 40 tpm, regular, ronchi (-).Abdomen : Soft and terderness, normal peristaltic. No liver and spleen enlargement.

    Turgor fast return (+)

    Extremities : Pulse 152 bpm, regular, Pressure/Volume: adequate, warm acral,

    BP: 100/60 mmHg

    Urogenital : Female, no abnormalititesA: Gastroenteritis without dehydration.

    P : IVFD D5% NaCl 0.225%: 30 gtt/i micro

    Paracetamol 3 x100 mg (pulv)

    Zink 1x20 mg

    porridge 700 ccal with 14 gram of protein

    Oralit 50-100 cc/each time diarrhea

    Laboratorium Findings (December 17th 2010) from Patology Clinic

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    Laboratorium Findings (December 17 2010) from Patology Clinic

    Adam Malik General Hospital

    31

    Test

    Result Normal Value

    Hemoglobin (Hb)

    Erytrocyes (RBC)

    Leucocytes (WBC)

    Hematocrit

    Thrombocyte (PLT)MCV

    MCH

    MCHC

    RDW

    Complete Blood Count8.80 g%

    3.97 x 106/mm3

    9.21 x 103/ mm3

    26.30 %

    404 x 103

    / mm3

    56.20 fL

    22.20 pg

    33.50 g%

    17.40 %

    11.1-14.4

    3.71-4.25

    6.0-17.5

    35-41

    217-49782-100

    24-30

    28-32

    14.9-18.7

    Neutrophil

    Lymphocyte

    Monocyte

    Eosinophil

    Basophil

    Cell Count23.80 %

    53.50 %

    20.20 %

    1.80 %

    0.700 %

    37-80

    20-40

    2-8

    1-6

    0-1

    Electrolit

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    32

    Sodium

    Potassium

    Chloride

    Ad random glucose

    Total bilirubin

    Direct bilirubin

    ALP

    SGOT

    SGPT

    Ureum

    Creatinine

    Uric acid

    ColorConsistency

    Blood

    Mucus

    Worm egg

    Amoeba

    Red blood cells

    White blood cells

    137

    2.0

    108

    Carbohydrate metabolism

    86.80 mg\dl

    Liver function test

    0.23 mg/dl

    0.09 mg/dl

    83 U/L

    24 U/L

    10 U/L

    Renal function test

    8.00 mg/dl

    0.23 mg/dl

    1.7 mg/dl

    Anal swab

    YellowWatery

    Negative

    Negative

    Negative

    Negative

    0-1

    0-1

    135-155

    3.6-5.5

    96-106

    < 200

    < 1

    0-0.2

    < 462

    < 32

    < 31

    < 50

    0.17-0.42

    < 5.7

    Negative

    Negative

    Negative

    Negative

    Di i

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    Discussion

    33

    Theory Case

    Diarrhea is the passage of unusuallyloose or watery stools, usually at least

    three times in a 24 hour period.

    However, it is the consistency of the

    stools rather than the number that is

    most important

    the patient was admitted with chiefcomplain diarrhea and the frequency is

    10 times in a day with the water is

    more than the dregs.

    Acute diarrhea is thus defined as an

    episode that has an acute onset and lasts

    no longer than 14 days

    the patient has acute diarrhea because

    he has diarrhea for 7 days

    A child with diarrhea should be assessedfor dehydration. In some dehydration,

    we must look at the condition (restless,

    irritable), sunken eyes, thirsty and

    eagerly to drink, and feel the skin pinch

    that goes back slowly

    the patient was restless, has sunkeneyes, thirsty and eagerly to drink.

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    Theory Case

    Replacement of fluid and electrolytes

    is the most important to treat diarrhea.

    This patient, general supportive care

    should include IVFD RL

    75cc/kgBB/4hours

    The children usual diet should be

    continued during diarrhea and

    increased afterwards. Food should

    never be withheld and the child's

    usual foods should not be diluted.

    Breastfeeding should always be

    continued.

    The patient continued to has

    breastfeeding addition with porridge

    diet of 700 ccal with 96 gram of

    protein

    By giving zinc as soon as diarrhea

    starts, the duration and severity of the

    episode as well as the risk of

    dehydration will be reduced

    On February 15th 2011, the patient got

    zinc for the first time.

    34

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    Summary

    It has been reported that a case of a 7-months-old

    girl diagnosed as gastroenteritis with mild-

    moderate dehydration. The diagnosis was

    established based on history taking, clinical

    manifestation, and laboratory finding. Thetreatment of this patient are IVFD D5% NaCl

    0.225%, Paracetamol, Zink, Oralit, and diet

    (porridge) 700 ccal with 14 gram of protein. The

    patient has been recovered after get medicationfor 4 days in Adam Malik General Hospital and

    was controlled at Adam Malik General Hospital

    gastroentererology polyclinic.35

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    36