case 11
TRANSCRIPT
• 45year male
• Presented with left flank pain
• USG: 9X10 cm mass lesion was noted in the left lumbar retroperitoneal region.
• FNAC- under guidance
• Other investigations: RFT, LFT, routine
biochemical investigations
• Complete hemogram
• USG : retroperitoneal sarcoma
• CT: Liposarcoma
ADRENAL MYELOLIPOMA
Adrenal myelolipoma is a benign tumour.
In 1905 Gierke first described the occurrence of a mass lesion in the adrenal glands.
They were subsequently termed formations myelolipomatoses by Oberling in 1929.
Myelolipomas account for approximately 3 to 5% of allprimary adrenal tumors.
Thought to arise from metaplasia of undifferentiatedstromal cells.
5th to 7th decades of life
Usually solitary
Associations :
with overproduction of dehydroepiandrosterone-
sulphate (DHEAS),
congenital adrenal hyperplasia caused by 21-
hydroxylase deficiency,
congenital adrenal 17 α-hydroxylase deficiency,
Cushing disease,
Conn syndrome,
adrenal insufficiency, and pheochromocytoma.
• Gross: capsulated, lobulated, yellow to red brown depending upon the relative proportion of fat and myeloid cells.
• Microscopy: islands of fat cells intermixed with hematopoietic stem ells, mainly myeloid and erythroid precursors, along with scattered megakaryocytes.
• SURGICAL EXCISION