care of client with liver and pancreatic disorder
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Caring for Clients with
Disorders of the Liver,Gallbladder, or Pancreas
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The Livery Functions
y Metabolizes: Glucose, proteins, and fats; Drugs,
chemicals, bacteria, and foreign elements
y Converts glycogen to glucose
y Regulates blood glucose
y Stores vitamins; Forms and excretes bile and
bilirubin
y Synthesizes factors for blood coagulation
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The Liver
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The Liver
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Jaundice
y Results from an abnormally highconcentration of the pigment bilirubin in theblood
y Visible, notably on the skin, oral mucousmembranes, and (especially) sclera
y
Three forms of jau
ndice
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Cirrhosisy Degenerative liver disorder caused by
generalized cellular damagey Pathophysiology and Etiology
y
Irreversibly damaged liver cellsy Consequences of damaged liver cells
y Affects digestion and metabolismy Fluid and electrolyte imbalancesy Impaired ability to metabolize hormones and detoxify
chemicals
y Types: Lannecs, postnecrotic, and biliary
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Cirrhosisy Assessment Findings: Signs and Symptoms
y Clinical manifestations: Compensated anddecompensated
y Chronic fatigue; Anorexia; Dyspepsia; Nausea;Clay-colored stools; Diarrhea
y Constipation; Tea-colored urine; Weight loss;Abdominal discomfort
y Shortness of breath; Nosebleeds; Signs ofincomplete estrogen metabolism in men
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Cirrhosisy Di stic Fi i s
y i r i s , l t sts, , I,r i is t li r sc : Demonstr te li ersenl r ed si e, nodul r confi ur tion, nddistorted lood flow
y Medic l nd ur ic l Managementy o s ecific cure; revents furt erdeterioration;
itamins andnutritional supplements; o
alcohol; dvanced liverdisease: estrict proteinintake; actuloseadministration
y Ursodeoxycholic acid; otassium-sparingantidiuretics; odium intake; latelettransfusion; iver transplantation
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Cirrhosisy Nursing Management
y Monitor vital signs, weight, intake, output, and
abdominal girth; Small mealsy Client response to drug therapy: Change in
mental status; Signs of GI bleed
y Client teaching: Liver disorder; Support groups;Treatment regimen; Home care
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Cirrhosis Complicationsy Portal Hypertension
y Blood backs up in portal systemy Congestion; Pressurey
Treatment: Sodium restriction; Drug therapy;Surgical and nonsurgical shunty Esophageal Varices
y Result of portal hypertensiony Esophageal bleeding: Treatment
y Sclerotherapy; Variceal band ligation;Sengstaken-Blakemore tube
y IV fluids; Blood products
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Cirrhosis
Complications
y Ascitesy Hepatorenal syndrome; Serum protein into
peritoneal cavity
y
Abdominal paracentesis: Procedu
re; Care; Dietand drug therapy
y Hepatic Encephalopathy: CNS manifestation ofliver failure: Coma and death; Increasedammonia levely CNS effects: Disorientation, confusion,
personality changes, and asterixis
y Treatment: Eliminating dietary protein;Removing residual protein; Depleting intestinalmicroorganisms
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Hepatitisy Pathophysiology and Etiology
y Liver inflammation after exposure to drugs or
chemicals, alcohol abu
se, or infectiony Viral infection: A, B, C, D, E, and G
y Hepatitis A: Oral-fecal route
y Hepatitis B, C, D: Chronic persistent; B and C
hepatocellu
lar carcinomay Other types: Autoimmune; Toxic; Drug induced
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Hepatitisy Assessment Findings: Signs and Symptomsy Associated with phases: Incubation; Preicteric,
prodromal, icteric, posticteric phases
y Assessment Findings: Diagnostic Findingsy Serology analysis; Liver biopsy
y Medical and Surgical Management
y Symptomatic treatment; Bed rest; IV fluid;
Vitamins and antiemeticsy Liver transplantation; Immunosuppressives
y Nursing Management
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Liver Tumorsy Abnormal mass of cells in the liver
y Benign or malignant
y Pathophysiology and Etiology: Common livermalignancymetastatic lesion from the breast,lung, or GI tracty Benign liver tumors: Tuberculosis; Fungal and
parasitic infections
y Assessment Findings: Jaundice; RUQ pain; Liverenlargement; Ascites
y Diagnostic Findings: Liver scan,ultrasonography, MRI, or CT scan; Biopsy
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Liver Tumorsy Medical and Surgical Management
y Hepatic lobectomy, cryosurgery, or cryoablation
y
IV chemotherapy or infu
sions directly intohepatic artery; Peritoneum drugs
y Chemotherapy radiation therapy
y Nursing Management
y
Ensu
re client safety and comfort; Su
pportventilation
y Medication administration
y Client and family teaching: Support, referrals
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Nursing Process
y Assessment
y
Diagnosisy lanning
y Implementation
y EvaluationofExpected utcomes
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Gallbladder Disordersy Cholelithiasis: Stones in the Gallbladder
y Choledocholithiasis: Stones located in thecommon bile duct
y Cholecystitis: Inflammation or infection of thegallbladder caused by formation of stones;Chronic or acute
y Pathophysiology and Etiology: Incidence
increases progressively with age: Women,middle age, multiple pregnancies, diabetes,and obesity; Bile stasis, dietary factors,infection; Gallstones impair passage of bile;Gallbladder inflamed; Distended with bile
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Gallbladder Disorders
y Assessment Findings: Signs and Symptoms
y Discomfort: Result of inflammation and contractilespasms; Digestion problems from reduced or absentbile; Swelling; Necrotic gallbladder
y Diagnostic Findings: Cholecystography; CT scan;Ultrasonography; Radionuclide imaging; PTCA;ERCP; MRC
y Medical, Surgical Management: NG tube;
Antibiotics; Parenteral fluids; Low-fat diet;Lithotripsy; Sphincterotomy; Laparoscopic, Opencholecystectomy
y Nursing Management
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Gallbladder Disorders
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Pancreatitis
y Inflammation of the Pancreas; Acute or chronic
y Acute Pancreatitis
y Mild form: Inflammation and edema of the
pancreas
y Severe form: Enzymatic digestion of the pancreas;Necrotic tissue, local and systemic complications
y Pathophysiology and Etiology
y Autodigestion; Swelling of pancreatic duct;Destruction of the pancreas
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Acute Pancreatitis
y Assessment Findings: Signs and Symptoms
y Severe mid- to upper abdominal pain radiating tosides and back; Vomiting
y Frothy and foul-smelling stools; Sign ofsteatorrhea; Increased fat in the stool
y Physical examination
y Diagnostic Findings
y Elevated serum and urine amylase, lipase, andliver enzyme levels
y Elevated blood glucose levels and white bloodcell counts; Low serum electrolyte levels; CT scan;Endoscopic examination
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Acute Pancreatitisy Medical and Surgical Management
y Relieve pain; Reduce pancreatic secretions
y Restore fluid and electrolyte losses
y Treat systemic complicationsy Nasogastric tube administration
y Fluid therapy; IV albumin; Diuretics
y Atropine or other anticholinergics: Reduce the
activity of the vagus nervey IV antibiotic therapy: Prevent localized abscesses
or treat systemic sepsis
y Diet therapy; Surgical intervention
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Acute Pancreatitisy Nursing Management
y Monitor client for life-threatening changes;
Alcohol withdrawaly Perform the prescribed treatment measures: NG
tube, IV fluids
y Perform assessments
y
Report any su
dden changes to physician
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Chronic Pancreatitisy Pathophysiology and Etiology
y Causes: Alcohol, hereditary predisposition,
hyperparathyroidism, autoimmune pancreatitis,trauma, and anatomic abnormalities
y Assessment Findings: Signs and Symptoms
y Digestive disturbances: Flatulence, vomiting,
diarrhea; Dark urine; Secondary diabetes; Light-colored stools; Weight loss
Diagnostic Findings: CT scans, MRI, ultrasound,and endoscopic retrograde study
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Chronic Pancreatitisy Medical and Surgical Management
y Treatments: Abstinence from alcohol, fat-free diet, andcorrection of associated biliary tract disease
y Drug therapy: Meperidine, narcotics, nonopioid methods, andpancrelipase
y Partial or total pancreatectomy
y Nursing Process
y Assessment;
y
Diagnosisy Planning;
y Implementation
y Evaluation of Expected Outcomes
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Pancreatic Cancery May occur in the glands head, body, or tail
y Pathophysiology and Etiology
y Accumulation of malignant cells
y Consequence of tumor development
y Factors that correlate with pancreatic cancer
y Assessment Findings: Signs and Symptoms
y
Leftu
pper abdominal pain; Jau
ndice, anorexia,weight loss; Obstructive jaundice; Pruritus;Ascites
y Diagnostic Findings: Abdominalultrasonography; CT scan; Biopsy
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Pancreatic Cancery Medical and Surgical Management
y Radical pancreatoduodenectomy
y Removes head of the pancreas; Resects the duodenum
and stomach; Redirects flow of secretions fromstomach, gallbladder, and pancreas
y Cholecystojejunostomy: Rerouting of pancreaticand biliary drainage
y Inoperable tumors: Radiation therapy orchemotherapy with 5-fluorouracil
y Nursing Management
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Pancreatic Surgery