cancer in the primary care setting theodore pollock, do, facoi june 21, 2012 1

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Cancer in the Primary Care Setting Theodore Pollock, DO, FACOI June 21, 2012 1

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Cancer in the Primary Care SettingTheodore Pollock, DO, FACOI

June 21, 20121

Leading Causes of Death, 2007

Source: CA Cancer J Clin 60:277, 2010.

© 2011 Rising Tide

Probability of Developing Cancer

Source: CA Cancer J Clin 60:277, 2010.

© 2011 Rising Tide

©2010 Rising Tide, Kft. All rights reserved. 4

Cancer in the Office

• Moles• Lymph Nodes• Weight Loss• Fever• Leukocytosis

©2010 Rising Tide, Kft. All rights reserved.

• Definition of Melanoma - A form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines.

• Estimated New Cancer Cases & Deaths from Melanoma in the U.S. in 2012

– New Cases: 76.250– Deaths: 9,180

5

The Mole

©2010 Rising Tide, Kft. All rights reserved.

• History– Exposure– Recent Change– Bleeding– Pregnancy

6

The Mole

©2010 Rising Tide, Kft. All rights reserved.

• Physical Exam– Margins– Ulcer– Lesions in Transit– Lymphadenopathy

• Biopsy

7

The Mole

©2010 Rising Tide, Kft. All rights reserved.

• History– Co-Existing Factors– Fever– Weight Loss

8

Lumps

©2010 Rising Tide, Kft. All rights reserved.

• Physical– Location

• Matted

– Consistency• Rubbery• Rock Hard

– Painful

9

Lumps

©2010 Rising Tide, Kft. All rights reserved.

• Temporal Factors• Coexisting Factors

– Diarrhea– Fevers– Diabetes– Meals-on-Wheels

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Weight Loss

©2010 Rising Tide, Kft. All rights reserved.

• CDC Definition of Fever– Temperature of 100°F or higher in the absence of

antipyretics.

• Temporal Factors– Infection

• Rigors

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Fever

©2010 Rising Tide, Kft. All rights reserved.

• Infection• Inflammatory Disease• Leukemia• Lymphoma• Renal Cell

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Differential Diagnosis

©2010 Rising Tide, Kft. All rights reserved.

• CBC• Differential Diagnosis

– Infection– Leukamoid Reaction– Neoplastic– N/A

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Leukocytosis

©2010 Rising Tide, Kft. All rights reserved.

• HGB• Platelets• Differential

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Neoplastic

©2010 Rising Tide, Kft. All rights reserved.

• Differential Diagnosis– CLL– CML– MDS / AML– Leukamoid Reaction

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Questions

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