cancer in kenya by anne korir

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Nairobi Cancer Registry, KEMRI Cancer in Kenya Presented by: Anne Korir, Head of Nairobi Cancer Registry Kenya Medical Research Institute

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Page 1: Cancer in kenya by anne korir

Nairobi Cancer Registry, KEMRI

Cancer in KenyaPresented

by:

Anne Korir,

Head of Nairobi Cancer Registry

Kenya Medical Research Institute

Page 2: Cancer in kenya by anne korir

Background: Cancer registries in KenyaPopulation-based registries• Two registries have been in existence for more than 10

years• Eldoret Cancer Registry located at MTRH established in 1998• Nairobi Cancer registry at KEMRI established in 2001

• Three registries are in early stages of development• Kisumu Cancer Registry partly funded by NCI• Embu and Nakuru Cancer registries - Grant Challenges Canada

(PAC Kenya)

Hospital-based registries• Moi Teaching & Referral hospital• Agakhan University hospital• Kenyatta National hospital

Page 3: Cancer in kenya by anne korir

Background: Cancer registries in Kenya

• Nairobi PBCR• Covers the Nairobi County a

population of 3.2 million (2009 census)

• Data is collected from over 20 hospitals in Nairobi

• Trained Cancer Registrars or Research Assistants visit the institutions on daily/regular basis to collect the data

Page 4: Cancer in kenya by anne korir

Results (2004-2008)

Distribution of cases registered (2004-2008), by age group and sex.

Page 5: Cancer in kenya by anne korir

Top 10 Male cancers in Nairobi (numbers)

109

109

154

157

192

194

243

293

333

606

0 200 400 600 800 1000

Bone

Larynx

Nasopharynx

Non-Hodgkin lymphoma

Liver

Kaposi sarcoma

Stomach

Large bowel

Oesophagus

Prostate

Top 10 cancers Males (numbers)

Number of cases

Page 6: Cancer in kenya by anne korir

Top 10 Female Cancers in Nairobi (numbers)

97

100

107

115

175

193

242

248

1073

1154

0 500 1000 1500

Brain, nervous system

Kaposi sarcoma

Non-Hodgkin …

Liver

Ovary

Stomach

large bowel

Oesophagus

Cervix uteri

Breast

Top 10 cancers Female (numbers)

Page 7: Cancer in kenya by anne korir

Top 10 Male Cancers (cumulative incidence 0-74)

0.4

0.5

0.5

0.8

0.8

0.9

1.4

1.6

1.8

5.2

0.0 2.0 4.0 6.0 8.0

Non-Hodgkin lymphoma

Mouth

Pancreas

Lung

Larynx

Liver

Stomach

Large bowel

Oesophagus

Prostate

Cum rate(0-74)

Top 10 cancers in males (cumulative incidence 0-74)

The chances or probability of being diagnosed with each of these cancers by age 74

Page 8: Cancer in kenya by anne korir

Top 10 Female Cancers (cumulative incidence 0-74)

0.2

0.3

0.5

0.7

1.1

1.5

1.6

1.9

5.4

6.1

0.0 2.0 4.0 6.0 8.0

Kaposi sarcoma

Brain, nervous system

Non-Hodgkin lymphoma

Liver

Ovary

Stomach

large bowel

Oesophagus

Cervix uteri

Breast

Top 10 cancers in females (cumulative incidence 0-74)

Cum rate (0-74)

Page 9: Cancer in kenya by anne korir

Age specific incidence rates (per 100,000) for major cancers in males

Page 10: Cancer in kenya by anne korir

Age specific incidence rates (per 100,000) for major cancers in females

Page 11: Cancer in kenya by anne korir

Cancer incidence and mortality in Kenya: MaleKenya estimates for year 2012

(GLOBOCAN, 2014)

• Prostate 14.4%; No. of new cases 2527; ASR 31.6/100,000; Mortality 12.6% No. of deaths 1692

• Oesophagus 10.7%; No. of new cases 1872; (ASR 20.5/100,000); Mortality 12.6%; No. of deaths 1692

Kenya 2012All Cases Numbers 40,999 (Male17531, Female 23468) or (41,000 cases annually)All deaths 28,453 per year (Male 13414; Female 15039)

Page 12: Cancer in kenya by anne korir

Cancer incidence and mortality in Kenya: Female

Estimates for year 2012 GLOBOCAN, 2014

• High incidence of both breast and cervix• Cervix 20.5%; No. of new

cases 4802; (ASR 40.1 per 100,000) Mortality 16.3%; No. of deaths 2451

• Breast 19%; No. of new cases 4465; (ASR 38.3 per 100,000); Mortality 13.1%; No. of deaths 1969

Page 13: Cancer in kenya by anne korir

-There is need to advocate for more resources to support cancer registries in the country

Incidence Reports:2000 – 20022004 – 2008Can be accessed at www.afcrn.orgwww.kemri.org

Page 14: Cancer in kenya by anne korir

• In 2011 Nairobi Cancer Registry included HIV data as part of routine data collection.

• A pilot study linking Cancer and HIV was done and results were published in Jan 2014.

Page 15: Cancer in kenya by anne korir

• Demographic and medical information missing/ not recorded in the patient’s notes

• Population boundaries – residence confused with place of birth

• Inadequate institutional support. Personnel, office space, equipment, office supplies

• Limited Funding• Capacity building, technical support• Lack of electronic hospital databases – data

capture is manual hence slow and prone to errors.• Hospitals data collection tools not standardized

• Personnel working in Medical records units not trained, basic tools e.g. ICD 10 coding manuals missing in some facilities

Challenges

Page 16: Cancer in kenya by anne korir

Overcoming some challenges

• Establishment of East Africa Registry Network in 2011

• Later (2012) upgraded to Africa Cancer Registry Network (AFCRN) now 26 members

• Opportunity for technical support (CanReg5)

• Capacity building• Annual meetings – sharing

data and point research work

Page 17: Cancer in kenya by anne korir

Ongoing studies

• Cancer survival studies (Breast, Cervix, Prostate, Oesophagus)

• Breast cancer staging study• Breast cancer biology study• Costing analysis study – to determine the cost of maintaining a population-based cancer registry (funded by CDC)

• Childhood cancer survival study

Page 18: Cancer in kenya by anne korir

Acknowledgement

1Kenyatta National Hospital (KNH) 14Nairobi Women’s hospital

2Nairobi hospital and Oncology Centre 15Metropolitan hospital

3MP Shah hospital 16Jamaa hospital

4Cancer Care Centre 17Gurunanak hospital

5Aga Khan hospital 18Nairobi West hospital

6Karen hospital 19South B hospital

7Mater hospital 20South C Alliance hospital

8Armed Forces Memorial hospital 21Mariakani Cottage hospital

9Nairobi hospice 22Kikuyu Hospital

10St. Mary's hospital 23Civil Registrar of births & deaths

11Nazareth hospital 24UoN Dental School

12Avenue hospital 25Kikuyu hospital

13Texas Cancer Centre 26Lion’s Eye unit

All Hospitals / institutions that contribute to the registry

Page 19: Cancer in kenya by anne korir

Acknowledgement

• KESHO Organizing Committee• Our sponsors – International Agency for Research on

Cancer (IARC)• Africa Cancer Registry Network (AFCRN)