camh12057

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Taming the adolescent mind: a randomised controlled trial examining clinical efficacy of an adolescent mindfulness-based group programme Lucy Tan 1,2 & Graham Martin 2 1 Department of Psychiatry, Principal Clinical Psychologist, Tan Psychological Services, RBWH, Herston Rd, Brisbane, Queensland, Australia. E-mail: [email protected] 2 Psychiatry, The University of Queensland, Brisbane, Queensland, Australia. Background: Mindfulness interventions with adolescents are in the early stages of development. This study sought to establish efficacy of a mindfulness-based group intervention for adolescents with mixed mental health disorders. Method: One hundred and eight adolescents (ages 1318) were recruited from community mental health clinics and randomised into two groups (control vs. treatment). All participants received treat- ment-as-usual (TAU) from clinic-based therapists independent of the study. Adolescents in the treatment con- dition received TAU plus a 5-week mindfulness-training programme (TAU+Mi); adolescents in the control group received only TAU. Assessments including parent/carer reports were conducted at baseline, postinter- vention and 3-month follow-up. Results: At postintervention, adolescents in the mindfulness condition experi- enced significant decrease in mental distress (measured with the DASS-21) compared to the control group (Cohen’s d = 0.43), and these gains were enhanced at 3-month follow-up (Cohen’s d = 0.78). Overall outcomes at 3 months showed significant improvement for adolescents in the mindfulness condition; in self-esteem, mindfulness, psychological inflexibility and mental health, but not resilience. Parents/carers also reported sig- nificant improvement in their adolescent’s psychological functioning (using the CBCL). Mediation analyses concluded mindfulness mediated mental health outcomes. Conclusions: Increase in mindful awareness after training leads to improvement in mental health and this is consistent with mindfulness theory. The mindful- ness group programme appears to be a promising adjunctive therapeutic approach for clinic-based adoles- cents with mental health problems. Key Practitioner Message ‘Taming the Adolescent Mind’ mindfulness-based programme is efficacious adjunctive treatment Mindfulness mediates mental health outcomes in this study The young people in this study improved in mental health Improvements were sustained postintervention and up to 3 months Keywords: Mindfulness; children; adolescents; psychological flexibility; mediation; clinical efficacy; RCT design; mental health Introduction The popularity of mindfulness-based psychotherapies is growing exponentially. There is general consensus in the literature that mindfulness is a learned skill that enhances self-management of attention (Baer, 2003; Bishop et al., 2004; Kabat-Zinn, 1994; Segal, Williams, & Teasdale, 2002). Mindfulness-based therapies seek to develop mindful attention using a variety of meditative exercises and activities and are generally effective in reducing anxiety, stress and depressive symptoms in adults (Baer, 2003). However, researchers are just beginning to explore the feasibility, acceptability and effectiveness of this approach for children and adoles- cents (Biegel, Brown, Shapiro, & Schubert, 2009). For some adolescents daily activities present many potential stressors. Some stress is an expectable response to stressful situations, but excess anxiety and challenges may interfere with the adolescents ability to cope. This results in attentional biases (Ehrenreich & Gross, 2002), cognitive distortions, emotional lability (Mineka & Gilboa, 1998) and physiological hyperarousal (Joiner et al., 1999). Research shows that 75% of chronic adult mental disorders rst present before the age of 25 years (Burns, Morey, Lagelee, Mackenzie, & Nicholas, 2007; Kessler et al., 2007). While patients may seek professional help in the rst year of symptom onset, many delay seeking initial consultation (Boydell, Gladstone, & Volpe, 2006) or do not seek help at all (Andrews, Henderson, & Hall, 2001). Evidence-based psychotherapies such as cognitive-behavioural therapy are moderately effective in treating a wide range of child- hood mental health issues, particularly anxiety prob- lems, but may be limited in their strength and © 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health. Published by John Wiley & Sons Ltd, 9600 Garsington Road, Oxford OX4 2DQ, UK and 350 Main St, Malden, MA 02148, USA Child and Adolescent Mental Health 20, No. 1, 2015, pp. 49–55 doi:10.1111/camh.12057

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Taming the adolescent mind: a randomisedcontrolled trial examining clinical efficacy of anadolescent mindfulness-based group programme

Lucy Tan1,2 & Graham Martin2

1Department of Psychiatry, Principal Clinical Psychologist, Tan Psychological Services, RBWH, Herston Rd, Brisbane,Queensland, Australia.E-mail: [email protected], The University of Queensland, Brisbane, Queensland, Australia.

Background: Mindfulness interventions with adolescents are in the early stages of development. This studysought to establish efficacy of a mindfulness-based group intervention for adolescents with mixed mentalhealth disorders. Method: One hundred and eight adolescents (ages 13–18) were recruited from communitymental health clinics and randomised into two groups (control vs. treatment). All participants received treat-ment-as-usual (TAU) from clinic-based therapists independent of the study. Adolescents in the treatment con-dition received TAU plus a 5-week mindfulness-training programme (TAU+Mi); adolescents in the controlgroup received only TAU. Assessments including parent/carer reports were conducted at baseline, postinter-vention and 3-month follow-up. Results: At postintervention, adolescents in the mindfulness condition experi-enced significant decrease in mental distress (measured with the DASS-21) compared to the control group(Cohen’s d = 0.43), and these gains were enhanced at 3-month follow-up (Cohen’s d = 0.78). Overall outcomesat 3 months showed significant improvement for adolescents in the mindfulness condition; in self-esteem,mindfulness, psychological inflexibility and mental health, but not resilience. Parents/carers also reported sig-nificant improvement in their adolescent’s psychological functioning (using the CBCL). Mediation analysesconcluded mindfulness mediated mental health outcomes. Conclusions: Increase in mindful awareness aftertraining leads to improvement in mental health and this is consistent with mindfulness theory. The mindful-ness group programme appears to be a promising adjunctive therapeutic approach for clinic-based adoles-cents with mental health problems.

Key Practitioner Message

• ‘Taming the Adolescent Mind’ –mindfulness-based programme is efficacious adjunctive treatment

• Mindfulness mediates mental health outcomes in this study

• The young people in this study improved in mental health

• Improvements were sustained postintervention and up to 3 months

Keywords: Mindfulness; children; adolescents; psychological flexibility; mediation; clinical efficacy; RCT design;mental health

Introduction

The popularity of mindfulness-based psychotherapies isgrowing exponentially. There is general consensus inthe literature that mindfulness is a learned skill thatenhances self-management of attention (Baer, 2003;Bishop et al., 2004; Kabat-Zinn, 1994; Segal, Williams,& Teasdale, 2002). Mindfulness-based therapies seek todevelop mindful attention using a variety of meditativeexercises and activities and are generally effective inreducing anxiety, stress and depressive symptoms inadults (Baer, 2003). However, researchers are justbeginning to explore the feasibility, acceptability andeffectiveness of this approach for children and adoles-cents (Biegel, Brown, Shapiro, & Schubert, 2009).

For some adolescents daily activities present manypotential stressors. Some stress is an expectable

response to stressful situations, but excess anxiety andchallenges may interfere with the adolescent’s ability tocope. This results in attentional biases (Ehrenreich &Gross, 2002), cognitive distortions, emotional lability(Mineka & Gilboa, 1998) and physiological hyperarousal(Joiner et al., 1999). Research shows that 75% ofchronic adult mental disorders first present before theage of 25 years (Burns, Morey, Lagelee, Mackenzie, &Nicholas, 2007; Kessler et al., 2007). While patients mayseek professional help in the first year of symptomonset, many delay seeking initial consultation (Boydell,Gladstone, & Volpe, 2006) or do not seek help at all(Andrews, Henderson, & Hall, 2001). Evidence-basedpsychotherapies such as cognitive-behavioural therapyare moderately effective in treating a wide range of child-hood mental health issues, particularly anxiety prob-lems, but may be limited in their strength and

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.Published by John Wiley & Sons Ltd, 9600 Garsington Road, Oxford OX4 2DQ, UK and 350 Main St, Malden, MA 02148, USA

Child and Adolescent Mental Health 20, No. 1, 2015, pp. 49–55 doi:10.1111/camh.12057

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durability. Mean treatment effect sizes (Cohen’s d) areapproximately d = 0.30, suggesting only modest effec-tiveness (Weisz, Jensen-Doss, & Hawley, 2006), whichmay not be lasting. Furthermore, Emslie, Mayes,Laptook, and Batt (2003) argued that childhood depres-sion and anxiety is often more contextual in nature thanin adults. As such innovative, nontraditional interven-tions may be required to augment traditional therapies(Hammen, Rudolph, Weisz, & Burge, 1999).

This study aimed to extend the research on the use ofmindfulness training with a psychologically symptom-atic adolescent population within community mentalhealth clinics. Using the Taming the Adolescent Mind(TAM) mindfulness treatment programme (described inTan & Martin, 2012a), a randomised controlled trial(RCT) was undertaken comparing treatment-as-usualand mindfulness treatment (TAU+Mindfulness) to a con-trol group receiving treatment-as-usual (TAU). Based onconsiderable research with adults, it was hypothesisedthat compared to the control condition, participants inthe TAM intervention would show greater improvementsin mental health (reduction in stress, depression, anxi-ety and cognitive inflexibility) and an increase in self-esteem and resiliency compared to the control group.External validation (i.e., parental reports) of the adoles-cents’mental health functioning was collected. A furtheraim of this study also examined whether changes inmindfulness mediated the changes in the primary out-comes (i.e., mental health symptoms).

Method

ParticipantsParticipants were recruited from three public community childand adolescentmental health clinics in amajor east-coast city ofAustralia. They had been approached by their case managers orhad responded to posters been placed around clinic campuses.Inclusion criteria included primary psychiatric diagnoses, with-out prior mindfulness training. Exclusion criteria were intellec-tual impairment, organic brain syndromes, chronic substanceabuse, acute suicidality and psychosis. Both the Ethics Com-mittees for Human Research at the Royal Children’s Hospitaland theUniversity Of Queensland approved the study protocol.

The sample was predominantly female (75%) which is repre-sentative of consumers who present at these clinics. Age rangedfrom 13 to 18 years (M = 15.40 years, SD = 1.55 years). Over-all, 69% of all participants were not onmedication.

Sample sizeTo detect whether mindfulness mediated mental health out-comes, sample size was estimated from the results of a poweranalysis performed on G*Power (available on-line) using med-ium effect size estimates from recent meta-analytic reviews ofMindfulness-based stress reduction programme (Grossman,Niemann, Schmidt, & Walach, 2004). This yielded a minimumtotal of 40 participants required for each group.

RandomisationParticipants were randomly allocated to two groups. Adoles-cents allocated to the control group (TAU) were advised therewould be an opportunity to attend mindfulness training at alater stage. Adolescents allocated to the experimental group(TAU+Mindfulness) continued with usual care and receivedmindfulness training. All participants and their parents/carerscompleted questionnaires over 3 time points (pre-, postinter-vention and 3-month follow-up). All participants received a $20gift card at the end of 3 months when all questionnaires hadbeen returned.

Treatment-as-usual (TAU)As per clinic practice, all adolescents were screened by a multi-disciplinary mental health clinician and diagnosed by a childand adolescent psychiatrist. Usual psychiatric care focused onappropriate clinical intervention for Axis 1 mental health diag-noses as identified by the International Classification of Dis-eases, Tenth edition (World Health Organization, 2008).Standard care provided in clinics comprised a mix of medica-tion, family therapy, expressive play therapy and manualisedcognitive-behavioural therapy that included psychoeducation,relapse prevention, coping with unpleasant thoughts, increas-ing pleasant activities scheduling, problem solving skills, goalsetting and crisis management. Participants in the TAU armwere informed they would be able to receive mindfulness inter-vention at a later stage.

MeasuresDepression Anxiety Stress Scale – short version (DASS-21; Lovi-bond & Lovibond, 1995) consists of three subscales assessingsymptoms of depression, anxiety and stress. Adolescents rateitems on a 3-point scale (0 = did not apply to 3 = most of thetime). DASS-21 has high internal consistency (Cronbach’sa = .80–.91); yields meaningful discrimination of the currentstate and change in states over time (Lovibond & Lovibond,1995). Confirmatory factor analysis has shown distinct depres-sion, anxiety and stress factors, as well as a general distress fac-tor (Henry & Crawford, 2005).

Rosenberg Self-Esteem Scale (Rosenberg, 1965) is a 10-itemself-report of adolescent self-esteem. Responses are rated on a4-point scale (1 = strongly agreed to 4 = strongly disagree)relating to overall feelings of self-worth or self-acceptance. It hashigh reliability, test–retest correlations are in the range of.82–.88 and Cronbach’s a is in the range of .77–.88 (Blascovich& Tomaka, 1993; Rosenberg, 1986). It has good reliability andvalidity across a large number of different sample groups.

Resiliency Scales for Children and Adolescents (RSCA;Prince-Embury, 2006) is a 64-item instrument with three self-report scales: Sense of Mastery Scale (which measures opti-mism, self-efficacy and adaptability); Sense of RelatednessScale (which measures trust, support, comfort and tolerance);and Emotional Reactivity Scale (which measures sensitivity,recovery and impairment). Item responses are rated on a 4-point scale (0 = never, 4 = almost always). Internal consisten-cies of the RSCA global scale for adolescents are in the range ofCronbach’s a = .92–.96 (Prince-Embury, 2006). It yields a totalResiliency score.

Avoidance and Fusion Questionnaire for Youth (AFQ-Y8 shortversion; Greco, Lambert, & Baer, 2008). Adolescents rateresponses to the eight items on a 4-point scale (0 = not at all trueto 4 = very true). High scores on the scale indicate greater psy-chological inflexibility characterised by high levels of experien-tial avoidance.

Children’s Acceptance and Mindfulness Measure (CAMMshort version; Greco, Smith, & Baer, 2011) comprises 10 itemsand assesses the adolescent’s self-report on mindfulnessawareness. Adolescents rate their responses on a 4-point scale(0 = never true, 4 = always true). The CAMM items assess threefacets of mindfulness in children and adolescents: (a) ‘Observ-ing’ involves the degree to which adolescents notice or attend tointernal phenomena (thoughts, feelings and bodily sensations),(b) ‘Acting with awareness’ refers to present moment awarenessand (c) ‘Accepting without judgment’ entails nonjudgmentalawareness and openness to experiencing a full range of internalevents.

The Child Behaviour Checklist (CBCL; Achenbach, 1999) wasdesigned to obtain, from parents or carers, multiaxial data onemotional and behavioural problems, social and academic com-petencies in children and adolescents. The CBCL consists of113 problem-behaviour items identifying mental health prob-lems in three general areas: ‘Internalising problems’ (includingwithdrawn, anxious/depressed, somatic complaints sub-scales), ‘Externalising problems’ (antisocial or undercontrolled

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.

50 Lucy Tan & Graham Martin Child Adolesc Ment Health 2015; 20(1): 49–55

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behaviours, including delinquency and aggression subscales)and ‘Total problems’ (overall mental health problems).

Taming the Adolescent Mind mindfulness-basedinterventionThe same group facilitator throughout the 2-year RCT deliveredthe TAM mindfulness-based protocol. The TAM interventionhas been previously described in detail by Tan and Martin(2012a). The 5-week adolescent programme ensured it wasdevelopmentally appropriate. The protocol was designed tomake mindfulness as accessible as possible to young peoplethrough simple sensory exercises, for example, the use of visualand tactile exercises of ‘describing’ and ‘judging’ as well asdirecting attention. A total of seven groups (with a minimum offour and a maximum of 12 participants per group) were con-ducted. A separate 1-hr precourse session for parents andcarers was delivered, providing the rationale of the treatment,attendance and outlining homework expectations.

Results

ParticipationA total of 108 participants were approached andassessed for eligibility, of these 91 participants met crite-ria after accounting for initial screening and completionof consent forms. Further attrition resulted in a finaltotal of 80 participants enrolled in the trial. Details ofparticipation flow are presented in Figure 1 (CONSORTguidelines; see Schulz, Altman, & Moher, 2010). In thetreatment condition, participants were considered tohave dropped out if they missed two sessions out of fiveof the TAM classes and failed to reply to follow-up con-tact. All participants who missed a previous week’s ses-sion were followed up by phone and offered additionalmake-up time at the following session, 18% overall(n = 8) receiving make-up sessions. The majority of par-

ticipants who missed sessions had valid reasons (exam-inations, sick, scheduling problem). Make-up sessionsinvolved a half hour one-on-one session before the startof the session.

To ensure comparability between the two groups aseries of t-tests were conducted on all preinterventionpsychological measures. No variables (with exception ofthe resiliency score) reached significance indicating theeffectiveness of randomisation.

Statistical analysesThe effect of the intervention was examined for eachvariable using mixed model analyses with time (time1 = preintervention, time 2 = postintervention and time3 = 3-months follow-up), and group as the independentvariable. Dependent variables were mental health out-comes (DASS-21), self-esteem (Rosenberg self-esteemquestionnaire), resiliency (RSCA-resiliency scales),mindfulness (CAMM), psychological inflexibility (AFQ)and parent/carer’s report of their adolescent’s behavio-ural problems (CBCL total). Each analysis used group asthe between-subject variable (two levels: TAU+Mindful-ness and TAU) and time as the within-subjects variable(three levels: time 1, time 2, time 3). An alpha of .05 wasused for all tests.

The main effects of group were examined to estimatethe overall difference in outcomes between the twogroups. The time by group interactions were examinedto see if changes in outcomes over time differed betweenthe two groups. If the interaction was significant thesewere followed up using post hoc tests to investigate sig-nificant differences between time points, that is, betweenpre- and postintervention, and between preinterventionand follow-up. Overall results are depicted in Table 1.

Mental health outcomesTests of between-subjects effects for group showed thatTAU+Mindfulness participants had improved signifi-cantly, achieving lower DASS-21 total scores overallcompared to control group participants, F(1,78) = 4.64,p = .034, gp

2 = .06. In addition, there was a significanttime by group interaction, which indicated the reductionin DASS-21 total scores over time differed between thegroups, F(2,156) = 9.79, p < .001, gp

2 = .11. Post hoctests of between-subject contrasts for time by groupinteractions showed that at time 1 (baseline) partici-pants in both groups scored similarly in psychologicaldistress. However, by time 2 TAU+Mindfulness partici-pants improved significantly with a decrease in theirpsychological distress, F(1,78) = 5.93, p = .017,gp

2 = .08. This improvement was maintained andreached greater significance at follow-up, F(1,78) = 16.51, p < .001, gp

2 = .18 when compared withparticipants in the control group.

Self-esteemTests of between-subjects effects for group showed thatself-esteem in the treatment group had improved signifi-cantly compared to control group participants, F(1,78) = 6.92, p = .01, gp

2 = .08. In addition, there was asignificant time by group interaction, which indicatedthat the increase in self-esteem scores over time differedbetween the groups, F(2,156) = 6.73, p = .002,gp

2 = .08. Post hoc tests of between-subject contrastsfor time by group interactions showed that at time 1

Enrolment

Randomised (n = 91)

10 did not meet inclusion criteria.

7 disinterested.

Allocation

46 assigned to TAU+Mi3 dropped out before intervention (scheduling, relocation, employment)

1 dropped out @ session one

45 assigned to TAU6 failed to return forms

(2 withdrew, 4 no response)

2 dropped out (disinterested)

43 analysed for study 37 analysed for study

Time 1 Baseline/Pre intervention

Time 2 Post intervention

Time 3

Follow-up

Assessed for eligibility (N = 108)

Figure 1. CONSORT diagram of participants through the study

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.

doi:10.1111/camh.12057 Clinical efficacy of adolescent mindfulness-based group programme 51

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participants in both groups scored similarly in psycho-logical distress. At time 2, there was no significant differ-ence between the groups, F(1,78) = 2.69, p = .11,gp

2 = .03. However by time 3, self-esteem of participantsin the treatment group had improved significantly com-pared with the control group, F(1,78) = 10.85, p = .001,gp

2 = .12.

ResiliencyTests of between-subjects effects for group showed thatat Time 1 there was a significant difference in the resil-iency scores between the two groups, with treatmentgroup participants achieving a higher score, F(1,78) = 60, p = .007, gp

2 = .09. No significant effect wasfound for time by group interaction, F (2,156) = 55.75,p = .137, gp

2 = .03.

Psychological inflexibilityTests of between-subjects effects for group showed thatpsychological inflexibility in the treatment group hadimproved significantly when compared to control groupparticipants, F(1,78) = 3.97, p = .05, gp

2 = .05. In addi-tion, there was a significant time by group interactionwhich indicated the decrease in psychological inflexibil-ity scores over time differed between the groups, F(2,156) = 12.23, p < .001, gp

2 = .14. Post hoc tests ofbetween-subject contrasts for time by group interactionsshowed that at time 1 participants in both groups scoredsimilarly in psychological inflexibility. By time 2 therewas a significant difference between the groups, F(1,78) = 9.57, p = .003, gp

2 = .11. At follow-up, partici-pants in the treatment group maintained improvementand the difference was significant when compared withcontrol group, F(1,78) = 18.73, p < .001, gp

2 = .19.

Parents’ report – CBCL Total scoreTests of between-subjects effects for group showed thatthere was a significant difference in how the parents ofthe two groups reported of their adolescent’s overall psy-chological functioning, F(1,78) = 11.71, p = .001,gp

2 = .13. Parents in the treatment group reportedimprovement in the adolescents. In addition, there was asignificant time by group interaction which indicated thedecrease in problem scores over time differed betweenthe groups, F(2,156) = 7.48, p = .001, gp

2 = .09. Posthoc tests of between-subject contrasts for time by groupinteractions showed that at time 2 there was no signifi-cant time by group effect, F(1,78) = 1.91, p = .17,

gp2 = .03. However at time 3, parents in the treatment

group reported a significant improvement in their ado-lescents in psychological functioning compared withcontrol group parents, F(1,78) = 10.84, p = .001,gp

2 = .12.

Mindfulness changesTests of between-subjects effects for group showed thatmindfulness scores in the treatment group hadimproved significantly achieving higher scores whencompared to control group participants, F(1,78) = 5.33,p = .024, gp

2 = .06. In addition, there was a significanttime by group interaction which indicated that theincrease in mindfulness scores over time differedbetween the groups, F(2,156) = 18.17, p < .001,gp

2 = .19. Post hoc tests, estimated by tests of between-subject contrast for time by group interactions, showedthat at preintervention participants in both groupsscored similarly in mindfulness scores. After interven-tion, the treatment group participants attained signifi-cantly higher mindfulness score, F(1,78) = .17.14,p < .001, gp

2 = .18, and also at follow-up, F(1,78) = .34.49, p < .001, gp

2 = .31. Effect sizes were inthe moderate range (ES = .18–.31).

Mediating effects of changes in mindfulnessTo test the hypothesis that changes in mindfulnesswould mediate mental health changes, meditationalanalyses were undertaken (Baron & Kenny, 1986). Forthe first step in the test of mediation, the independentvariable (treatment group) accounted for a significantproportion of the variability in the dependent variable(change in mental health scores – DASS-21 total), via asimple linear regression analysis. A decrease in mentalhealth symptoms (i.e., improvement) in mental healthscores was significant (standardised b = �.42, p < .001),establishing that there was an effect that may be medi-ated (see Figure 2).

In step 2 of the analysis, a regression was conductedto determine whether the initial independent variable(i.e., treatment) was associated with change in the medi-ator (i.e., mindfulness). A significant effect of treatmentgroup on mindfulness change was observed (standar-dised b = .55, p < .001). In step 3 of mediation analysis,change in the mediator (mindfulness) must predictchange in the dependent variable (mental health) whencontrolling for the independent variable (group). Theresult of this was significant (standardised b = �.42,

Table 1. Comparingmeans and standard deviations of study variables over time

Variables

TAU TAU+Mi p (time 9 group)

Time 1 Time 2 Time 3 Time 1 Time 2 Time 3Time 1–

2Time 1–

3

Mental health 68.43 (24.26) 69.24 (27.61) 65.78 (26.75) 67.07 (25.98) 57.62 (26.02) 44.33 (27.91) .017** <.001***Mindfulness 17.22 (8.63) 16.03 (8.37) 16.24 (7.80) 16.58 (5.60) 20.37 (5.67) 22.79 (7.35) <.001*** <.001***Resiliency 31.27 (9.59) 31.68 (10.35) 31.49 (9.86) 36.30 (8.91) 35.74 (9.50) 38.81 (10.79) .542 .210Psychological Inflexibility 17.59 (7.19) 18.05 (7.21) 17.78 (6.75) 17.58 (7.69) 14.84 (6.98) 12.14 (7.53) .003** <.001***Self-esteem 11.03 (5.25) 11.30 (4.73) 10.86 (4.50) 11.84 (4.90) 13.70 (5.14) 16.07 (8.35) .105 <.001***CBCL total 68.35 (10.15) 66.41 (8.35) 67.46 (7.94) 62.60 (9.78) 60.63 (10.63) 57.60 (9.04) .171 .001***

p = for time 9 group contrasts, SD in parentheses, time 1 = preintervention, time 2 = postintervention, time 3 = 3-month follow-up.**Significant p < .05.***Significant p < .01.

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.

52 Lucy Tan & Graham Martin Child Adolesc Ment Health 2015; 20(1): 49–55

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p < .001). Finally, results indicated the effect of treat-ment group on mental health change was reduced andbecame statistically not significant (standardisedb = �.19, p = .11) when mindfulness was entered intothe model, establishing that mindfulness change com-pletely mediated the impact of treatment group on men-tal health change.

Discussion

The TAM group therapy was developed as an interven-tion for adolescents with mixed clinical mental disor-ders. The TAM aimed to enhance self-management ofregulating attention to improve affect regulation by pro-moting mindfulness, decentring from problematicthoughts and emotions and increasing social–emotionalawareness or resiliency in adolescents with clinical men-tal health problems. This study is the first randomisedcontrolled trial using an age-appropriate mindfulnessmeasurement to assess a manualised TAM mindfulnesstreatment programme to ameliorate multiple symptomsof mental health distress in a clinical cohort. Our resultsdemonstrate that levels of mindfulness increased signifi-cantly from pre- to posttherapy and pre- to follow-up,with effect sizes in the small to moderate range. This isan important study given previous empirical investiga-tions did not include formal mindfulness measure-ments. Our study enhances and strengthens the body ofempirical findings through inclusion of formal mindful-ness measurements.

Results of this RCT of manualised mindfulness inter-vention for adolescents with mixed mental health diag-noses were very encouraging. Across all but one primaryoutcome (resiliency) TAU+mindfulness was superior toTAU. These gains were maintained or even enhanced at3-month follow-up. As predicted, increases in mindful-ness were shown to completely mediate the relationshipbetween mindfulness intervention and improvement inmental health improvement. Our findings are importantbecause they provide support for a central tenet of mind-fulness-based treatment approach – that by regulatingattention and awareness we can improve coping andmental health through a process of reperceiving, andincreased acceptance, regardless of the emotional con-tent (Shapiro, Carlson, Astin, & Freedman, 2006). Tan

and Martin (2012b) have previously shown that highscores for mindfulness are related to fewer mental healthsymptoms. Focused awareness brings attention to thepresent moment (either good or bad), so the adolescentmight become more aware of life stress and experiences.Active acceptance leads to acknowledgement of a diffi-cult situation and dealing with it constructively. Assuch, active acceptance is a form of emotion-focusedcoping and positively related to mental health (Nakam-ura & Orth, 2005). While this expectation is almostuniversally believed, there has been limited empiricalevidence for the claim in an adolescent clinical popula-tion. This is the first study to report evidence for theassociation with an adequate sample in an adolescentclinical context.

The significant reductions in psychological inflexibilityfound for the treatment group may also explain changesin attention and acceptance processes hypothesised tooccur as a result of mindfulness practice. Mindfulnesspractice attempts to cultivate nonjudgmental, moment-to-moment awareness to inner, as well as external stim-uli. The development of this skill may result in the abilityto shift and redirect attention to the present momentrather than being ‘fused’ with thinking about past orfuture experiences.

Given the documented relationship between mindful-ness practice and stress (Kabat-Zinn, 1990; Kabat-Zinn,Lipworth, & Burney, 1985; Sethi, 1989), depression(Segal et al., 2002), anxiety (Kabat-Zinn et al., 1992;Semple, Reid, & Miller, 2005), psychological inflexibilityand acceptance (Hayes & Fieldman, 2004; Lau &McMain, 2005; Linehan, 1993) in adults, it is notablethat the TAU+Mindfulness arm in this study of adoles-cent sample was associated with improvement in overallmental health distress. A significant strength of thisstudy was the inclusion of parent/carer reports. Parentsin the TAU+Mindfulness arm reported significantimprovement in their adolescents compared to parentsin the control group with a large between-group effectsize (gq

2 = .13).A nonsignificant effect was found for resiliency in this

study. No reasons can be put forward to explain the ini-tial difference between our randomised groups – espe-cially given similar scores on other measures atpreintervention. The authors are unaware if the RSCAtest is sensitive to clinical change; this limitation mayrequire future investigation using a more sensitive mea-surement of resiliency.

Resilience is viewed as the capacity of an individual tomobilise health-sustaining resources from a myriadsources – family, community and culture. Anecdotally,adolescents in mental health services believe that to sur-vive, it is important that one is self-reliant, and notdepend on or trust others. Cauce, Felner, and Primavera(1982) have demonstrated that positive external connec-tions or resources to self are important variables in ado-lescent resiliency, but of equal importance is theadolescent’s perception of that support, their ability torecognise, seek and utilise the support; all importantinteractive processes which contribute to adolescentresiliency. As such, there may be a sleeper effect; moretime may be required in follow-up, beyond the 3 monthsused in this study to establish improved resilience.Given there are no other comparative adolescent studiesavailable, further research is warranted to examine the

Group assignment

(TAU vs TAU+Mi)

Change in mental health (DASS-21)

β = -.42, p < .001

Group (TAU vs TAU+Mi)

Change in mental health (DASS-21)

Change in mindfulness

β = -.19, p = .11

β = .55, p < .001 β = .42, p < .001

Figure 2. Mindfulness changes mediate mental health outcomes

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.

doi:10.1111/camh.12057 Clinical efficacy of adolescent mindfulness-based group programme 53

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efficacy and effectiveness of mindfulness treatment onadolescent resiliency.

LimitationsA primary limitation of this study is the reliance on self-report measures, subject to both bias and social desir-ability. These factors were not controlled for in thisstudy. Social desirability is the tendency for persons toreport what the examiner or therapist expects of them,instead of what they might report to be their ‘real’ situa-tion. However, according to Corrigan and Shapiro (2010)this effect may be reduced by permitting participants tocomplete study measures anonymously, using observa-tions or reports by outside party and randomised con-trolled trial. Although this study was randomised,allowing participants to complete clinical measuresanonymously may be practically and ethically problem-atic as these adolescents present with moderate tosevere mental health disorders require proper psychiat-ric care and follow-up. Neither the adolescents nor theirparents necessarily know what each self-report measureactually measures, as measures are administered as asuite. We would argue that even if participants wereshowing early social desirability response bias, eleva-tions in mindfulness scores might not necessarily havebeen sustained from posttreatment to follow-up timepoints, when initial enthusiasm for (or from) the trainingmay have diminished.

A second limitation in the study is the lack of dataexamining the possibility of facilitator effect. As the sameclinician conducted all group interventions, it may beargued that participants improved in mental health out-comes due to a ‘zealous and engaging’ facilitator.Although this may be plausible, it is unknown how longa facilitator effect on intervention lasts. McCowan, Nev-ille, Crombie, Clark, and Warner (1997) examined thisissue in a process and outcome study of childhoodasthma and found that the effect of a facilitator lasts onlyfor the period of intervention. In this study, participantsin the treatment condition continued to improve in theirmental health long after the intervention had ceased,and this result was statistically significant. A final argu-ment to support the fact that real change occurred overtime is that parents did not receive any part of the mind-fulness intervention and acted as external reporters.

These possible limitations must be weighed againstthe overall strengths of this research programme. Ourstudy contributes to the literature supporting the effi-cacy of mindfulness intervention for adolescents withmixed mental health disorders by: (a) including ran-domisation and a control group undertaken in natural-istic setting. Moreover, the sample studied wasappropriate to the hypothesis being tested, thus leadingto results appropriately generalisable, (b) Smith, Glass,and Miller (1980) have highlighted that the internalvalidity of outcome studies and effect sizes are highlycorrelated. In this study, sample size calculation wasundertaken a priori, ensuring the sample size was ade-quate, reducing the probability of error and enhancinginternal validity; (c) This study utilised a comprehensiveassessment battery with validated age-appropriate mea-sures, especially establishing mindfulness changeswhich previous studies neglected; (d) Obtaining collat-eral reports and observations from third parties (i.e.,parents/carers) over time, adding external validity and

credibility to the study and (e) Evaluating a prescribed,manualised mindfulness intervention. All of theseprovide important initial steps in identifying an effica-cious treatment programme.

Clinical implicationsThe study presented results demonstrating the effi-cacy of a 5-week session mindfulness-based interven-tion for adolescents with mental health disorders.This programme is one of the few supported byempirical evidence, and for which actual mindfulnesschanges were measured, and follow-up data collected.Results suggested that the majority of adolescentswho completed the intervention reported improve-ments in mental health functioning. These improve-ments were confirmed by third-party reports. Finally,the small-group format and its short duration sug-gest that TAM is a useful adjunctive option forenhancing psychological health for distressed adoles-cents. As such its cost-effectiveness warrants furtherresearch.

Acknowledgements

The authors thank the Children’s Hospital of Queensland, Divi-sion of Child and YouthMental Health Services for their supportin this study. No external funding was received for this work.The authors have declared that they have no competing orpotential conflicts of interest.

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Accepted for publication: 27 January 2014Published online: 28 February 2014

© 2014 The Authors. Child and Adolescent Mental Health © 2014 Association for Child and Adolescent Mental Health.

doi:10.1111/camh.12057 Clinical efficacy of adolescent mindfulness-based group programme 55