c14: microdosimetry in nuclear medicine: emerging importance of auger-electron data
DESCRIPTION
C14: Microdosimetry in nuclear medicine: emerging importance of Auger-electron data Alan Nichols University of Surrey, UK & Manipal University, India. Auger electrons and dosimetry. Cancer Therapy with Auger Electrons: Are We Almost There? - PowerPoint PPT PresentationTRANSCRIPT
January 2013
C14:C14:
Microdosimetry in nuclear medicine:Microdosimetry in nuclear medicine:emerging importance of Auger-electronemerging importance of Auger-electron
datadata
Alan NicholsUniversity of Surrey, UK
& Manipal University, India
January 2013
Cancer Therapy with Auger Electrons: Are We Almost There?
A. I. Kassis, J. Nucl. Medicine 44 (2003) 1479-1481
The Problem of Auger Emitters for Radiological Protection
D. Bingham et al., Radiation Protection Dosimetry 92 (2000)
219-228
Radiotoxicity of Iodine-125 and Other Auger-electron-emitting
Radionuclides: Background to Therapy
S. Adelstein et al., Cancer Biother. Radiopharm. 18 (2003) 301-306
The Electron Spectrum from the Atomic De-excitation of 131Xe
A. Kovalik et al., J. Electron Spectrosc. Relat. Phenom. 95 (1998)
232-254
Auger electrons and dosimetry
January 2013
Immediate and future:
22-26 August 2011, IAEA Headquarters, Vienna, Austria
Intermediate-term Nuclear Data Needs for Medical Applications: Cross Sections and
Decay DataA.L. Nichols, S.M. Qaim and R. Capote Noy
IAEA report INDC(NDS)-0596, September 2011
January 2013
Radionuclide
Requirements Comments
67Ga, 111InAuger electrons may become an issue
Both 67Ga and 111In finding increased application in internal radiotherapy
71GeAuger electrons may become an issue
77BrAuger electrons may become an issue
99Tcm Auger-electron (Ee < 25 keV) and other low-energy electron (Ee < 1 keV) data for microdosimetry
Regularly used for diagnosis, but also increased application in therapeutics
103PdAuger electrons
January 2013
Radionuclide
Requirements Comments
123IAuger electrons Regularly used for diagnosis,
but also increased application in therapeutics
140NdAuger electrons may become an issue
Auger and EC decay; in-vivo generator (140Pr)
178TaAuger electrons may become an issue
Auger and EC decay; in-vivo generator (178W)
193Ptm, 195Ptm Auger electrons may become an issue
Large number of Auger electrons emitted
197HgAuger electrons may become an issue
January 2013
over to Filip and Tibor → C20