bupropion

Reactions 1451 - 11 May 2013 S Bupropion Visual hallucinations in an elderly patient: case report An 81-year-old man experienced visual hallucinations following treatment with bupropion for fatigue associated with multiple sclerosis. The man, who had a history of posttraumatic stress disorder with chronic auditory hallucinations, initiated bupropion 150mg once daily [route not stated] for fatigue associated with multiple sclerosis. His dosage was later increased to 150mg twice daily. He experienced new onset visual hallucinations following dose elevation with exacerbation of auditory hallucinations [duration of treatment to reaction onset not stated]. Bupropion was tapered off, and his visual hallucinations resolved; auditory hallucinations also regressed returning to baseline level. No recurrence of visual hallucinations was reported. Author comment: "Based on his clinical course, it appears that his visual hallucinations were bupropion-induced." Karino S, et al. Bupropion-Induced visual hallucinations in a veteran with posttraumatic stress disorder and multiple sclerosis. Journal of the American Geriatrics Society 61 (Suppl. S1): S29 abstr. A35, Apr 2013. Available from: URL: http://dx.doi.org/10.1111/jgs.12263 - USA 803086428 1 Reactions 11 May 2013 No. 1451 0114-9954/10/1451-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Reactions 1451 - 11 May 2013

SBupropion

Visual hallucinations in an elderly patient: casereport

An 81-year-old man experienced visual hallucinationsfollowing treatment with bupropion for fatigue associated withmultiple sclerosis. The man, who had a history of post-traumatic stress disorder with chronic auditory hallucinations,initiated bupropion 150mg once daily [route not stated] forfatigue associated with multiple sclerosis. His dosage was laterincreased to 150mg twice daily. He experienced new onsetvisual hallucinations following dose elevation withexacerbation of auditory hallucinations [duration of treatmentto reaction onset not stated]. Bupropion was tapered off, andhis visual hallucinations resolved; auditory hallucinations alsoregressed returning to baseline level. No recurrence of visualhallucinations was reported.

Author comment: "Based on his clinical course, it appearsthat his visual hallucinations were bupropion-induced."Karino S, et al. Bupropion-Induced visual hallucinations in a veteran withposttraumatic stress disorder and multiple sclerosis. Journal of the AmericanGeriatrics Society 61 (Suppl. S1): S29 abstr. A35, Apr 2013. Available from:URL: http://dx.doi.org/10.1111/jgs.12263 - USA 803086428

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