brown cv - astmh · web view2009 invited participant, vivax malaria research: 2009 and beyond....

1CURRICULUM VITAE

Name: BROWN, Graham Vallancey MB BS(Melb), FRACP, MPH(Harvard), PhD(Melb), FAFPHM, FACTM, FAAHMS, AM

Date of Birth: 6th May, 1946

University and professional Training:1970 MB BS University of Melbourne, Bachelor of Medicine & Bachelor of Surgery

(First Class Hons Med)1974 MRACP Member, Royal Australasian College of Physicians1983 PhD University of Melbourne1978 MPH Harvard University School of Public Health1978 FRACP Fellow of the Royal Australasian College of Physicians 1983 FAFPHM Fellow of the Australian Faculty of Public Health Medicine

FACTM Fellow of the Australasian College of Tropical Medicine2015 FAAHMS Fellow of the Australian Academy of Health and Medical Sciences

Research and Clinical Interests . Malaria vaccine development. Cell biology of malaria. Cytoadherence and antigenic variation of Plasmodium falciparum. Field studies of acquisition of immunity to malaria. Clinical infectious diseases surveillance of diseases in travellers. Mathematical modelling of infectious diseases. Global health

Current positions

Professor Emeritus, University of MelbourneChair Executive Committee, and Vice-Chair, Board Roll Back Malaria (RBM) Partnership

Positions held:

1974-1975 Relieving Specialist Paediatrician/Physician, Public Health Department, Papua New Guinea.

1975-1977 Lecturer in Medicine, University of Dar Es Salaam, Tanzania.1978-1981 Senior Research Officer, The Walter and Eliza Hall Institute of Medical

Research, Melbourne.1979-1984 Visiting Associate (Medical) Royal Melbourne Hospital.1981-1983 Research Fellow, The Walter and Eliza Hall Institute of Medical Research.1983 Acting Professor of Medicine, University of Papua New Guinea.1984 Senior Research Fellow, The Walter and Eliza Hall Institute of Medical

Research.1985 Assistant Physician, Royal Melbourne Hospital.1987 Honorary Assistant Physician, AIDS Service, Royal Melbourne Hospital.1989 Physician, Royal Melbourne Hospital.1989-2001 Principal Research Fellow, The Walter and Eliza Hall Institute of Medical

Research. 1990 Special Study Leave - University of Oxford, Institute of Molecular Medicine 1991-2006 Head, Infectious Diseases Service, Royal Melbourne Hospital1992-1997 Head, Immunoparasitology Unit, The Walter and Eliza Hall Institute of

Medical Research1996-2006 Head, Victorian Infectious Diseases Service, Royal Melbourne Hospital1997-3/99 Head, Division of Infection and Immunity, The Walter and Eliza Hall

Institute of Medical Research

21992 Senior Associate (Associate Professor), Department of Medicine, Royal

Melbourne Hospital1994 Professor/Director, Infectious Diseases and International Health, Royal

Melbourne Hospital/University of Melbourne/The Walter and Eliza Hall Institute of Medical Research

1999 Visiting Professor, University of Virginia, Charlottesville, USA (Special Study Leave)

1999-2007 Head, Department of Medicine (RMH/WH), University of Melbourne. James Stewart Professor of Medicine

2001- Professorial Associate, Division of Infection and Immunity, The Walter and Eliza Hall Institute of Medical Research

2003-2007 Head, Centre for Clinical Research Excellence in Infectious Diseases at RMH (NHMRC-supported Programme)

2005 Interim Director, Nossal Institute for Global Health, University of Melbourne2010 Visiting Professor, Centre for International Health Research, University of

Barcelona (January – April)2006- Foundation (First) Chair in Global Health, University of Melbourne2006-2014 First Director, Nossal Institute for Global Health, University of Melbourne

Some Contributions to the Community

1996-1998 Committee Member, Overseas Service BureauHonorary Medical Advisor and Board Member, Overseas Service BureauCouncil, Australian Volunteers International

2000- Member, Commonwealth Panel of Experts for Crisis Management (CAPE), Emergency Management Australia

2000-2003 Member, Ministerial Advisory Committee on AIDS, Hepatitis C and Related Diseases (MACAHRD)

2000-2003 Member of Clinical Trials and Research Committee (CTARC) of the Australian National Council on AIDS, Hepatitis C and Related Diseases (ANCAHRD)

2001-2006 Member, Genetics Advisory Committee, Department of Human Services 2001-2006 Member, Executive Committee of the Arthritis Foundation of Victoria Centre

for Rheumatic Diseases2002-2003 Chair, Working Party, Guidelines for the Management of HIV Infected

People who Knowingly or Recklessly Risk Infecting Others, Department of Human Services, Victoria

2002-2004 Editorial Advisory Committee Member, Special Report of the Chief Medical Officer, Department of Health and AgeingMember, Victorian Advisory Committee on Infection Control (VACIC), Department of Human Services

2004-2007 Member, Advisory Board, National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Westmead, NSW

2004-2007 Chair, Greek Fund for Arthritis Research at the Royal Melbourne Hospital2004 Convenor, Healthy Relations: Should global health be on the foreign affairs

agenda. The Alfred Deakin Innovation Lectures, Melbourne2005 National Influenza Pandemic Action Committee (NIPAC), Department of

Health and Ageing and the National Health and Medical Research Council2005-2006 Member, Victorian Medicines Advisory Committee, Department of Quality

and Safety, Department of Human Services (University Representative)2006-2008 Member, Genetic Services Development Committee, Department of Human

Services, Victoria2006 Thinking Games: Exercise your mind- Creating our own future. City of

Melbourne

32006 Avian Influenza: Impact, solution and readiness. Asialink, University of

Melbourne.2007-2010 Member, Asia Australia Mental Health Advisory Council, University of

Melbourne2008 Invitee, Australia 2020 Summit, (Co-chair Sub-group Health Inequalities)

Parliament House, Canberra2010 Guest Speaker, Victorian Infection and Immunity Network 2010 Invited

Participant, The White Ribbon Alliance for Safe Motherhood Australia, The Prime Minister’s Lodge, Canberra

2010 Invited speaker, Trinity Grammar Leadership Recognition Dinner

Many talks to community groups

Service to the ProfessionMember, State Committee Royal Australasian College of PhysiciansCo-opted Examiner for Fellowship of the Royal Australasian College of Physicians

1991-1997 Honorary Secretary, Asia Pacific Committee, Royal Australasian College of Physicians.

1987-1999 Member, Asia Pacific Committee, Royal Australasian College of Physicians2001 Member, Scientific Advisory Board, Macfarlane Burnet Centre for Medical

Research2000 Council, Australasian Society for Infectious Diseases2001-2002 Director, Victorian Clinical Genetics Services Limited2001- Member, Advisory Committee, Clinical Epidemiology and Health Service

Evaluation Unit, Royal Melbourne Hospital2001-2010 Chair, Scientific Advisory Board, Queensland Institute of Medical Research,

Brisbane2001- Director, Australian International Health Institute, University of Melbourne2001- Advisory Board, Centre for International Child Health, Royal Children’s

Hospital2001-2007 Chair, Murdoch Children's Research Institute Career Grants Committee2002-2007 Victorian Nosocomial Infection Surveillance Coordinating Centre Advisory

Committee2002-2008 Member, Scientific Advisory Council, Melbourne Health2004- Member, WEHI/RMH Clinical Advisory Group2006- Member, Health and Development Alliance2008 Member, Melbourne Health Research Advisory Council

Local publications and newspaper articlesProfessor Graham Brown reflects on his career in infectious diseases.Medical Journal of Australia. 196:C5-C5. 2012Games rivals but health partners. The Age, 15th August 2008A preventable shame. The Age, 16th January 2009

Contributions to National Science1986 Member, Scientific Committee, Saramane Pty Ltd. (Past Chairman)1996-1998 Member, Regional Grants Interview Committee, NHMRC1999-2000 Chair, Discipline Panel, NHMRC1996-1997 NHMRC Representative, Consultative Committee for the Australian Centre

for International and Tropical Health and Nutrition1996-1998 Member, Regional Grants Interview Committee (NHMRC)1999-2000 Chair, Discipline Panel, National Health and Medical Research Council

41998 Committee Member. Third Quinquennial Report by an External Committee to

the Board of the Menzies School of Health Research, Darwin2001-2010 Chair, Scientific Advisory Board, Queensland Institute of Medical Research,

Brisbane2001-2010 Member, Appointments and Promotions Committee, Queensland Institute of

Medical Research, Brisbane2000-2003 Member, Clinical Trials and Research Committee (CTARC) of the Australian

National Council on AIDS, Hepatitis C and Related Diseases (ANCAHRD)2002-2003 Chair, NHMRC Grants Review Panel 2b-Microbiology2003-2004 Member, NHMRC Centres of Clinical Research Excellence Committee2004-2007 Chair, Expert Advisory Group on Antimicrobial Resistance (EAGAR),

NHMRC2004-2007 Member, Advisory Board, National Centre for Immunisation Research and

Surveillance of Vaccine Preventable Diseases, NSW2005 Inaugural Symposium, Nossal Institute for Global Health, Melbourne2006 Chair, Centres of Clinical Research Excellence Grants Review Committee.

NHMRC2006 Member, National Clinical Research Steering Committee to oversee the

development of a National Clinical Research Framework, Office for Science and Medical Research (OSMR), NHMRC

2006-2009 Member, Executive Committee, Australian Cancer Grid, Department of Innovation, Industry and Regional Development, DIIRD. Consortium of the Molecular Medicine Informatics Model (MMIM)

2007- Member, Medical Advisory Board, Sylvia and Charles Viertel Charitable Foundation, ANZ Trustees Philanthropy Partners

2007 Participant, Malaria Reference Group, AusAID2007-2011 Member, Australian Government Advisory Committee, WHO Collaborating

Centre for Reference and Research on Influenza2008 Member, Expert Commentator Panel, NHMRC2008 Participant, Malaria Reference Group, AusAID, Honiara2008 Keynote Speaker: High Flyers Think Tank 2008, Australian Academy of

Sciences. “Preventative health: Science and technology in prevention and early detection of disease”

2009 Participant, Malaria Reference Group, AusAID, Vanuatu2010 Participant, Malaria Reference Group, AusAID, Brisbane2011 Participant, Malaria Reference Group, AusAID, Brisbane2012 Invited Speaker, Australasian Vaccines and Immunotherapeutics Development

Conference, Brisbane

Contributions to International Science1987 World Health Organization Tropical Diseases Research Centre, Ndola1987 Rockefeller Foundation Great Neglected Diseases Meeting, Kenya1987 Fifth meeting of the Papua New Guinea Malaria Collaborative Programme1988 Steering Committee, Applied Field Research in Malaria (WHO/TDR

Programme), World Health Organization, Brazil1988 Steering Committee Meeting, FIELDMAL, World Health Organization1988 Reviewer, Kenya Malaria Research Programme for the Centres for Disease

Control, Atlanta, Georgia, USA1989 Steering Group Working Meeting IMMAL/FIELDMAL, World Health

Organization, Geneva1990 Steering Committee Meeting, Applied Field Research in Malaria, World

Health Organization, Geneva1991 Reviewer, Medical Research Council of Great Britain, The Gambia

51991 Member, Steering Committee for Applied Field Research in Malaria

(FIELDMAL), UNDP World Bank/WHO Special Program for Research and Training in Tropical Diseases (TDR).

1993 Reviewer, Duke University-Tanzania Collaborative Program Review, Ifakara, Tanzania

1994 Participant, Informal Consultation on Research Priorities for the Integrated Management of the Sick Child in the South-East Asian and Western Pacific Regions, World Health Organization, Hanoi, Vietnam

1994 Working visit, Discussions with Eijkman Institute for Molecular Biology and US Naval Medical Research Unit No 2, Jakarta, Indonesia

1995 Convener and Chairman, Malaria Task Force Working Group Meeting, World Health Organization, Geneva

1996 Chair, Steering Committee, IMMAL Special Program for Research and Training in Tropical Diseases. World Health Organization, Chiang Mai, Thailand

1998 Chairman, Steering Committee, Vaccine Discovery Research, World Health Organization, Geneva, Switzerland

1996 Chair, Steering Committee on the Immunology of Malaria (IMMAL), UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases

1995-1996 Member, Steering Committee, Vaccines against Malaria, UNDP/World Bank/World Health Organization Special Programme for Research and Training in Tropical Diseases

1996-1999 Board Member, World Federation of Parasitologists1997-2000 Chair, Steering Committee Vaccine Discovery Research (VDR),

UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases

1998-2003 Member, Strategic Advisory Council, Bill and Melinda Gates Children’s Vaccine Program, Program of Appropriate Technology in Health, Seattle, Washington

1999- Site Director, GEOSENTINEL Program for Global Surveillance of Infectious Diseases

2002- Malaria Advisory Committee, Initiative for Vaccine Research (IVR), World Health Organization

2002-2009 Scientific Consultants Group, USAID Malaria Vaccine Development Program, USA

2009- Chair, Scientific Consultants Group, USAID Malaria Vaccine Development Program, USA

2002-2007 Member, Malaria Vaccine Advisory Committee, (MALVAC) World Health Organization

2003 Assessment Committee, International Collaborative Research Grants Scheme, NHMRC/Wellcome Trust

2006 Member, Study Committee, Institute of Medicine (IOM) of the National Academies. Review of the US Army Medical Research and Material Command Malaria Vaccine Research Program.

2006- Scientific Advisory Board, US Military Infectious Diseases Research Programs (MIDRP).

2007- Chair, External Advisory Committee KEMRI -Wellcome Programme, Kenya2008- Chair, Malaria Vaccine Advisory Committee, (MALVAC) World Health

Organization2008 Co-Chair WHO Scientific Forum on Malaria vaccines: Understanding Current

and Future data from Clinical Trials - Scientific, Regulatory and Public Health Expectations

2008 Chair, Rational Design of Children’s Malaria Vaccine Consultation workshop, Washington DC

62009 Member, Advisory Board, Asia Pacific Malaria Elimination Network

(APMEN)2010 Board Member, Roll Back Malaria (RBM) Partnership (Research and

Academia constituency)2010 Invited Speaker, Joint International Tropical Medicine Meeting and

international Malaria Colloquium 2010, Bangkok Thailand2011 Invitee, WHO-UNAIDS Vaccine Advisory Committee meeting on Challenges

in the development of Vaccines against HIV, TB and Malaria (Istanbul)2011 Member Scientific Review Committee ICGEB New Delhi2011 Member, Steering Committee, Malaria Elimination Scientific Alliance 2012 Chair MALVAC Scientific Forum: “Accelerating Development of Second

Generation Malaria Vaccines2012-2016 Chair Executive Committee, and Vice-Chair, Board Roll Back Malaria (RBM)

Partnership 2012 Malaria 2012 Conference (AusAID) Member technical Advisory Group, and

Session Chair2016 Chair, Scientific Consultants Group, USAID Malaria Vaccine Development

Program, USA

Editorial Responsibilities1996-2001 Co-Editor, Acta Tropica1996 Member, Publications Committee, International Society of Travel Medicine

Contribution to Debate on Ethics in ScienceScientific Secretary, Ethics Committee, The Walter and Eliza Hall Institute of Medical ResearchMember, Ethics Committee, Royal Melbourne Hospital.

2001 Convenor, Dean’s Lecture Series Ethics Symposium. “Ethics of international and clinical practice”, Melbourne, VIC

2002 Convenor, Dean’s Lecture Series Ethics Symposium. “Cloning and embryonic stem cell research: Does Australia need a moratorium?” Melbourne, VIC

2003 Convenor, Dean’s Lecture Series Ethics Symposium. “Who pays for lunch – a conflict of interest” Melbourne

2004 Convenor, Dean’s Lecture Series Ethics Symposium. “A question of ethics – who decides?” Melbourne, VIC

2005 Convenor, Dean’s Lecture Series Ethics Symposium. “Designer babies: are we going too far?” Melbourne, VIC

2006 Convenor, Dean’s Lecture Series Ethics Symposium. “End of life decisions – do advanced care directives work?”

Honours and Awards1970 Stirling Prize for Surgery1971 Wall Award for Junior RMO (Royal Melbourne Hospital)1990 Australian Academy of Science/Australian Academy of Technological

Sciences/Royal Society Exchange Programme1992 The Eric Susman Prize, Royal Australasian College of Physicians2001 Inaugural Royce Abbey Oration, Rotary Club of Melbourne-Latrobe Inc2005 Presidential Oration, Australasian Society of Infectious Diseases2006 Innovation in Information Technology, Victorian Public Healthcare Award,

Department of Human Services“Guidance DS: A web-based computerised decision support system to facilitate implementation and governance of clinical guidelines and better use of medicines - Melbourne Health”

2007 The Chairman’s Award of Melbourne Health Outstanding leadership and excellence in their chosen field.

72008 Ashdown Oration, Australian College of Tropical Medicine, Asia Pacific

International Conference on Travel Medicine, 2008 Fellowship, Queensland Institute of Medical Research2010 Member, Order of Australia2011 Lifetime Achievement Award (Minister of Health, State of Victoria)2014 Brownless Medal of the Melbourne Medical School (University of Melbourne)2015 RMH Research Hall of Fame inductee2015 Elected to Fellowship Australian Academy of Health and Medical Sciences

Postgraduate and Undergraduate Teaching and Assessment1996- Lecturer and Examiner for Medical Undergraduate students, University of

MelbourneLecturer and Examiner Postgraduate Trainees (Royal Australasian College of Physicians)

1996- Examiner for Fellowship of the Royal Australasian College of PhysiciansMember, Task Force Semester 5 of New Curriculum in Medicine, University of Melbourne

1999-2005 Chair, Board of Examiners, 4th Year (Semester 8/9) Medicine, University of Melbourne

2004-2005 Chair, Board of Examiners, Final year (Semester 12) Medicine, University of Melbourne

Student Supervision (not including post-doctoral fellows of the laboratory)1987 PhD, Dr Beverley-Ann Biggs1996 MD, Dr Tom Kotsimbos

MD, Dr James McCarthyMMed, Dr Sheila Baingana

1996 PhD, Dr Stephen Rogerson (awarded Chancellor’s Prize for PhD thesis)1997 BMedSci, Mr T Syme (co supervised with Dr L Schofield)1998 MD, Dr F Bowden2000 BSc (Hons), Ms Dianna Moir2001 AMS, Mr Greg Kelly

BSc (Hons), Ms Jessica Salmon, Ms Emily Mann2002 AMS, Ms Sandra Hallamore2003 PhD, Dr James Beeson (awarded Neil Hamilton Fairley Fellowship and Premiers

Award)2004 PhD, Ms Rintis Noviyanti2007 PhD, Ms Emily Mann2010 PhD, Dr Benjamin Cowie (co supervised with Professor H Kelly)2010 PhD, Dr Leon Worth (co supervised with Assoc Prof Jim Black) 2010 PhD, Dr Jack Richards (co supervised with Dr James Beeson) 2007 PhD, Dr Kylie Horne (Principal supervisor Dr Stephen Rogerson) 2008 PhD, Dr Doug Johnson (Principal supervisor Dr Joe Torresi) (PhD in progress)2008 PhD, Ms Caroline Chua (co supervised with Dr Philippe Boeuf) 2009 PhD, Dr Justin Denholm (Principal supervisor Dr Emma McBryde)2009 PhD, Mr Keovathanak Khim (co supervised with Dr Peter Annear) 2014 PhD, Ms Shamista Selvarajah (co-supervised with Dr Mike Duffy)2011 PhD, Ms Gabrielle Josling (co-supervised with Dr Mike Duffy)2014 PhD Dr Geoffrey Quail (Co-supervisor Professor Joy Damousi)2016 PhD Mr Andrew Teo (Co-supervisor Professor Stephen Rogerson)2016 PhD in progress Ms Jingyi Tang (Co-supervised with Dr Mike Duffy and Dr

Michaela Petter)

Trainee Specialists in Infectious Diseases

Michelle Ananda-Rajah Harin Karunajeewa Anna Pierce

8Narin Bak Tom Kotsimbos Jack RichardsKirsty Buising Lyn-Li Lim Kasha SinghPat Charles Sharon Lewin David SmallwoodBen Cowie Christopher MacIsaac Karin ThurskyJulian Elliott Caroline Marshall Steven TongMichelle Giles Daniel O’Brien Paul VintonMargaret Hellard Mark Page Ian WoolleyGrant Jenkins Anton Peleg Leon WorthDoug Johnson Marc Pellegrini Raina MacIntyre

Some Local, National and International PresentationsInternational Conferences1987 Lecture, Malaysia-Singapore Congress of Medicine, Kuala Lumpur1988 Invited Speaker, Joint IMMAL/FIELDMAL Steering Working Group Meeting,

World Health Organization, Geneva1988 Working visit, Centre for Vaccine Development, University of Maryland, Baltimore,

USA1989 UCLA Symposium, Parasites, Molecular Biology, Drug and Vaccine Design,

California, USA1990 Site visit, Kilifi Coastal Research Unit (KEMRI – Wellcome Laboratories), 1990 Participant, VII International Congress of Parasitology, Paris1990 Invited Speaker, Molecular Parasitology Club, London1990 Invited Speaker, American Society of Tropical Medicine and Hygiene, New Orleans1990 Invited Speaker, V-NOW Symposium on Genetic Variation of Malaria Parasites,

Leiden1990 Invited Speaker, University of Stockholm, Stockholm1991 Invited Speaker, American Tropical Medicine and Hygiene Meeting, Boston1991 Invited Participant, SEAMEOTROPMED Meeting on Containment of Drug Resistant

Malaria, Bangkok1992 Invited Speaker, Annual Scientific Meeting, Royal Australasian College of Physicians

in conjunction with the Australasian Society of Infectious Diseases1992 Participant, Molecular Parasitology Meeting, John D and Caterhine T MacArthur

Foundation Consortium, Woods Hole, Massachusetts1992 Participant, XIIIth International Congress for Tropical Medicine and Malaria,

Bangkok1993 Invited Speaker, Papua New Guinea Institute of Medical Research Jubilee

International Colloquium, Madang1993 Participant, Australian Society of Parasitology Annual Meeting, Queensland1994 Invited Speaker and Session Chairman, VIIIth International Congress of Parasitology,

Izmir, Turkey1994 Invited Speaker, World Health Organization Meeting, Biotechnology and World

Health: Vaccines and other medical products produced by genetic engineering. Review of risks and benefits. Geneva

1995 Keynote Speaker, Workshop Conference of the Indonesian Association of Internal Medicine, Manado, Indonesia

1995 Invited Speaker, Institute of Medicine, National Academy of Sciences USA, Workshop on Malaria Vaccines. Vaccines against Malaria - Hope in a Gathering Storm. Washington DC, USA

1995 Invited Speaker, Second Asia-Pacific Conference on Medical Genetics, Jakarta, Indonesia

1995 Invited Speaker, A Nobel Minisymposium at the Nobel Forum. The molecular background to severe malaria. Stockholm, Sweden

1995 Site visit, Malaria Vaccine Epidemiology and Evaluation Project, Papua New Guinea1995 Site visit, Eijkman Institute of Molecular Biology and US Naval Medical Research

Unit, Jakarta, Indonesia1996 Invited Speaker, 26th Congress of the International Society of Haematology,

Singapore

91996 Invitee, First Annual Tropical Meeting, Wellcome Trust Centre for Clinical Tropical

Medicine, Liverpool, UK1997 Committee Symposium Speaker, 20th International Congress of Chemotherapy,

Sydney1997 Invited Speaker, Commonwealth Partnership in Medicine: Progress and Promise.

Edinburgh, UK1997 Chairman, Steering Committee Meeting, IMMAL Special Program for Research,

Training and Tropical Diseases, World Health Organization, Geneva Switzerland1997 Member, Scientific Working Group on Vaccine Discovery Research, World Health

Organization, Geneva Switzerland1997 Member, Scientific Working Group on Vaccines for Malaria, World Health

Organization, Geneva Switzerland1997 American Society for Tropical Medicine and Hygiene Conference, Orlando, Florida1998 International Conference on Emerging Infectious Diseases in the Pacific Rim, Bali,

Indonesia1998 Site visit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia1999 TDR Meeting on Malaria and Schistosomiasis Vaccine Research in Asia,

UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Manila, Philippines

2000 Invited Speaker, First Joint Scientific Meeting, Royal Australasian College of Physicians and the Royal College of Physicians Thailand

2001 Invited Speaker, Second Advanced Course in Vaccinology, Annecy, France.2002 Invited Participant, Malaria Liver Stage Antigen (LSA) Meeting, Rockville,

Maryland, USA. 2003 Session Chair, Invited Speaker, 13th European Congress of Clinical Microbiology and

Infectious Diseases, Glasgow, UK 2003 Invited Participant, Global Vaccine Research Forum, Seoul, Korea2003 Invited Participant, Regional Scientific Meeting of Malaria Vaccine Researchers,

World Health Organization, Mozambique2004 Invited Speaker, 11th International Congress on Infectious Diseases, Cancun, Mexico. 2004 Invited Speaker, The Fifth Princess Chulabhorn International Science Congress,

Bangkok, Thailand2005 Participant, International Society for Travel Medicine, Lisbon Portugal2005 Invited Speaker, NHMRC Centre for Clinical Research Excellence Workshop,

Canberra 2005 Invited Speaker, Malaria Vaccine Technology Roadmap (TRM), MIM Pan-African

Malaria Conference, Yaoundé, Cameroon 2005 Invited Participant, Update of development of vaccines against vivax malaria.

MALVAC, World Health Organization, Cali, Columbia2005 University Representative, U21 Health Research Planning Workshop, University of

Virginia, Charlottesville, USA2007 Invited Speaker, Malaria Symposium and the Establishing of the Indonesian Malaria

Research Network, Jakarta2007 Invited University Representative, APRU World Institute Workshop “The Role of

Universities in Addressing Emerging Public Health Threats in the Asia Pacific Region, Peking University

2007 Invited Participant, Joint WHO/EU Meeting. Update on development of vaccines against malaria in pregnancy (MiP) and Plasmodium vivax. Barcelona, Spain

2007 Chair, WHO Malaria Vaccine Advisory Committee Meeting, Barcelona, Spain2007 Invited Participant, Malaria Gordon Conference, Oxford, UK2007 Invited Speaker, Malaria Vaccines for the World, Royal Society of London2007 Invited Participant, Rural Health Challenges in Resource Poor Countries: Developing

the Research Agenda, The Wellcome Trust, London2007 Invited Participant, Bill and Melinda Gates Foundation Malaria Forum, Seattle

Washington2008 Invited University Representative, U21 Workshop and Symposium, Dublin, Ireland

102008 Chair, WHO Malaria Vaccine Advisory Committee Meeting, Geneva, Switzerland2008 Invited Participant, High-level Consultation on Scaling up research and learning for

better health, World Health Organization, Divonne-les-Bains, France2008 Invited Participant and member of Scientific Advisory Committee, Global Vaccine

Research Forum and parallel satellite symposia, World Health Organization, Institut Pasteur, Paris, France

2009 Invited Participant, Vivax malaria research: 2009 and beyond. Panama Canal, Panama

2009 Chair, Scientific Forum: Progress and challenges with whole-organism malaria vaccines. World Health Organization, Senegal, Dakar

2009 Chair, Vaccine Advisory Committee (MALVAC), World Health Organization, Senegal, Dakar

2009 Invited Participant, Consortium of Universities for Global Health Annual Meeting, Bethesda, Washington

2009 Member, Scientific Advisory Board, US Military Infectious Diseases Research Programs, Washington DC

2009 Facilitator, Integration Strategies Consultative Group, malERA Integration Strategies (GATES), Ghana

2010 Invited Participant, malERA Zenith Week Meeting, Washington DC2010 Co-Chair, Transmission Blocking Vaccines Workshop, Bethesda, Maryland 2010 Invited Participant, Second meeting of the Disease Reference Group on Malaria

(DRG1) Meeting, World Health Organization, London2010 Invited Participant, International Congress of Parasitology ICOPA XII, Melbourne2010 Participant, Consortium of Universities for Global Health, University of Washington,

Seattle2010 Temporary Advisor, Scientific Forum: Measures of efficacy of anti-malaria

interventions against malaria transmission, World Health Organization, Geneva2010 Invited Participant, Second meeting of the GMP/IVR Joint Technical Expert Group

on malaria vaccines in pivotal phase 3 trials and beyond. World Health Organization, Geneva

2010 Chair, Vaccine Advisory Committee (MALVAC), World Health Organization, Geneva

2010 Keynote Speaker: Joint International Tropical Medicine Meeting/Malaria Colloquium, Bangkok

2010 Board Member, Nineteenth RBM Partnership Board Meeting, Lusaka, Zambia2011 Invited Speaker, The Australasian Society for Infectious Diseases Annual Scientific

Meeting, Lorne2011 Session Chair The Bill & Melinda Gates Foundation Malaria Forum, Seattle,

Washington, USA.2011 Board Member, Nineteenth RBM Partnership Board Meeting, WuXi, China2012 Chair, Malaria Vaccine Advisory Committee (MALVAC), World Health

Organization, Geneva2012 Chair, Scientific Forum, World Health Organization, Geneva2012 Board Member, Twentieth RBM Partnership Board Meeting, Lausanne, Switzerland2012 Board Member, Twenty-first RBM Partnership Board Meeting, Dakar, Senegal2012 - present Chair, Executive Committee, and Vice-Chair Board Roll Back Malaria

Partnership.2014 Plenary Speaker Asia-Pacific Travel Health Conference

Local Conferences2001 Australian Society for Infectious Diseases, Melbourne2002 Australian Society for Microbiology Annual Scientific Meeting, Melbourne2004 International Symposium on Human Rights in Public Health: Research and Practice,

Melbourne

112006 Invited participant, Health and Development Alliance, A Symposium to build on

post-tsunami lessons. Monash University, Melbourne2006 Invited speaker, Specialist Medical Aid Symposium, Royal Australasian

College of Surgeons, Melbourne2008 Invited speaker, Australian Society for Microbiology, Melbourne2008 Invited speaker, Australian Rheumatology Association (Victoria

Branch) Annual Scientific Meeting, Melbourne2009 Invited speaker, Towards the MDGs: “More money for health, more

health for the money”, AusAID Seminar, Canberra2011 Invited speaker Global Health Forum (AMA Doctors in Training

Subdivision)2012 Keynote Lecture The evolving role of the Doctor. Future Med

Melbourne. AMSA2012 Keynote Lecture RMH Academic Symposium “Outcomes Research”

National Conferences1986 International Congress of Parasitology, Brisbane1987 Royal Australasian College of Physicians Meeting, Broadbeach, Queensland1997 Plenary Speaker, XIVth International Congress of Nephrology, Sydney2000 Plenary Speaker, 7th PHAA Immunisation Conference, Surfers Paradise, Queensland2001 Orphan Vaccines: Bridging the Gap, Palm Cove, Cairns, QLD2001 12th World Congress of Neurosurgery, Sydney, NSW2004 Participant, Australasian Society for Infectious Diseases, Alice Springs, NT2005 President’s Address, Australasian Society for Infectious Diseases, Busselton, Western

Australia2005 Convenor, The Alfred Deakin Innovation Lectures. Healthy relations: Should global

health be on the foreign affairs agenda? Melbourne2006 Participant, 37th PHAA Annual Conference Sydney, Tackling the determinants of

health from the bush to Bondi.2006 Chairmanager, 23rd NRL Workshop on Serology, Melbourne2006 Invited Speaker, Pandemic Preparedness and Response Forum, Sydney2007 Chair, 2nd National Immunisation Workshop, University of Sydney2007 Invited Speaker, The Way Forward, Chronic Disease Self-Management in Australia,

Melbourne2007 Invited Speaker, Building the Clinical Research Profession, Clinical Research

Excellence 07, Melbourne2007 Plenary Speaker, 9th Australian Palliative Care Conference, Melbourne2007 Invited Speaker, RBWH Health Care Symposium. New horizons in

health care. Royal Brisbane Hospital2008 Plenary Speaker, Clinical Research Excellence 08, Brisbane2008 Plenary Speaker, Challenges of global health session. Australasian

Research Management Society (ARMS), Hobart2008 Invited Speaker, Australian Society for Microbiology Annual

Scientific Meeting, Melbourne2009 Member, Moderated panel session. Clinical Research: Expanding

Australia’s place in the world. Clinical Research Excellence 09, Melbourne

2010 Capacity Building Grant Conference, Mt Eliza2012 Plenary Lecture 4th Australasian Vaccines and Immunotherapeutics

Development Meeting, BrisbaneOther Invited Seminars/Committees1990 John Radcliffe Hospital, Oxford, UK

Liverpool School of Tropical Medicine and Hygiene, Liverpool, UK

12London School of Hygiene and Tropical Medicine, London UK

1993 Steering Committee, Applied Field Research in Malaria (FIELDMAL). UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR)

1993 Steering Committee, Immunology of Malaria (IMMAL) UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR)

1993 Member, International Review Committee, Duke University, Tanzania Collaborative Review Programme

1994 Chairman. Informal consultation on research priorities for the integrated management of the sick child in South-East Asia and Western Pacific Regions. World Health Organization, Hanoi, Vietnam.

1997 Chair, Scientific Workshop on Vaccines and Diagnostics for Malaria and Schistosomiasis, World Health Organization, Guangzhou, China

2000 Karolinksa Institute, Sweden (Thesis opponent)Eijkman Institute for Molecular Biology, Jakarta, Indonesia

2007 Member, Institute Scientific Advisory Board, Kenya Medical Research Institute/Wellcome Trust Research Programme

2009 Chair, Institute Scientific Advisory Board, Kenya Medical Research Institute/Wellcome Trust Research Programme

2009 Invited Member, Site Visit Committee, Department of Parasitology and Mycology, Pasteur Institut, Paris

2011 Member Scientific Advisory Board review of the US Military Malaria Vaccine Program

Local Committees1999- Interim Board Member, Bio21 Australia Ltd2001- Member, Executive Committee of the Arthritis Foundation of Victoria Centre for

Rheumatic Diseases2001-07 Chair, Career Grants Committee, Murdoch Children’s Research Institute2002- Member, Board of Directors, Australian International Health Institute2002- Advisory Committee, Victorian Nosocomial Infection Surveillance Coordinating

Centre (VICNISS), Department of Human Services2002- Member, Scientific Advisory Committee, Bio21 Australia Ltd2002-07 Advisory Board, Leadership Program, University of Melbourne2003- Governor, Royal Melbourne Hospital Foundation2004- Member, Clinical Advisory Group, The Walter and Eliza Hall Institute/Royal

Melbourne Hospital Medical Curriculum Committee, University of MelbourneChair, Strategy and Development Committee, Australian International Health Institute, University of Melbourne

2006-07 Member, Heads’ Development and Support Program Reference Group, University of Melbourne

Organisation of local, national and international meetings2000 Organizing Committee, Molecular Approaches to Malaria, Lorne2004 Organizing Committee, Molecular Approaches to Malaria, Lorne2008 Organizing Committee, Molecular Approaches to Malaria, Lorne

Grants/Contracts Awarded1996-1999 National Health and Medical Research Council block funding to The Walter and

Eliza Hall Institute of Medical Research1996–2005 Australia-Indonesia Medical Research Initiative, AusAID $1.8m1995 Coinvestigator, Strengthening immunization and malaria control in Vietnam.

AusAID $3.6m2001-2003 Molecular analysis of interaction of P.falciparum infected erythrocytes.

NHMRC Project 145699. $570,000

132002-2005 The molecular basis of host-pathogen interactions. NHMRC Program Grant

215201. $11,540,0002003-2007 Centre for Clinical Research Excellence in Infectious Diseases. NHMRC

CCRE 219275 $2,000,0002005-2009 Capacity Building Grant in Population Health Research, Mathematical

modelling for improved planning of infectious disease control policy. NHMRC 358425 $3m

2006-2010 Host parasite interactions: Disease, pathogenesis and control. NHMRC Program Grant 406601 Brown (CIB) $13,500,000 (in association with AF Cowman, BS Crabb, E Handman, MJ McConville, GI McFadden, L Schofield, TP Speed)

2006 Infrastructure grant, (third stage) Australian Cancer Grid, Department of Innovation, Industry and Regional Development, DIIRD. Consortium of the Molecular Medicine Informatics Model (MMIM) ($11,000,000)

2007 Live Cell Imaging Facility – Inflammation, brains, cancer and malaria. Ian Potter Foundation #20070545 $100,000

2007-2012 Intermittent preventive treatment with azithromycin-containing regimens for the prevention of malarial infections and anaemia and the control of sexually transmitted infections in pregnant women in Papua New Guinea. Bill & Melinda Gates Foundation, Global Health Program; European Union Framework Programme 7. Rogerson SJ, Mueller, Siba P, Menendez C. (Co investigators: Beeson J, Brown G, Davis T, Karunajeewa H, Gaita L, Mola G, Zimmerman P.) USD $2,440,886

2008-2010 Transcriptional control of antigenic variation in the malaria parasite Plasmodium falciparum. ARC Discovery Project DP0879293. MF Duffy, GV Brown. $294,606

2011-2013 Are alternative-histones important regulators of transcription in Plasmodium falciparum? ARC Discovery Project DP110100483. MF Duffy, AT Papenfuss, GV Brown, Z Bozdech, MS Kobor. 2011 $130,000; 2012 $130,000; 2013 $100,000.

2011-2013 Identifying malaria PfEMP1 proteins that elicit antibodies associated with protection from cerebral malaria. NHMRC Project 1007954. MF Duffy, A Papenfuss, T Theander, SJ Rogerson, GV Brown. $478,307

2011-2013 Appropriate Health Diagnostic Tools for developing countries using mobile phones and inexpensive sensors. Science and Industry Endowment Fund (SIEF) CSIRO Research Grants. Black J, Bruenig M, Trowell S, Day N, Brown G, Woodrow G, Furman S, Sonenberg E, Palaniswami M, Khandoker A, $ 430,000

2012-2014 Immunity to malaria in pregnancy NHMRC Project Grant 1024441 Rogerson S, Brown GV $532,987.50

Patents1984-Expression of P. Falciparum Polypeptides from Cloned cDNA. DJ Kemp, RL

Coppel, RB Saint, RF Anders, GV BROWN, AF Cowman, GF Mitchell. International PCT/AU84/00016; Australia Patent No. 569722 (granted 1987); Europe 0,134,799 (granted 1993); Greece 81750 (granted 1984); Hong Kong 1182/93 (granted 1993)

1989-Antigens of Plasmodium Falciparum. DJ Kemp, RL Coppel, RB Saint, AE Bianco, RF Anders, GV BROWN, AF Cowman, GF Mitchell. International PCT/AU85/00223; Great Britain 2176191 (granted 1989); United States Continuation 5126 264 (granted 1992); Divisional continuation 08/203748 (filed Dec 1995); Europe 0193568 (granted 24/03/93); Hong Kong 1326/93 (granted 1993)

Publications:

14Books: 1. Therapeutic Guidelines. A manual to assist in the rational purchase and

prescription of drugs. Upunda G, Yudkin J, BROWN G. (1980) African Medical and Research Foundation.2. Guidelines to Drug Usage. Upunda G, Yudkin J, BROWN GV. (1983) Macmillan Press, London.3. Protecting Australia from Communicable Diseases: Everybody’s Business. (2004) A Special Report of the Chief Medical Officer. Department of Health and Ageing (BROWN GV, Editorial Advisory Committee Member).

1. Brookfield DS, Liston WA, BROWN GV, (1977) Use of spironolactone in the prevention of acute mountain sickness of Kilimanjaro. East African Med J 54:689-691.

2. BROWN GV, Liston WA, Brookfield DS, (1977) Spironolactone in acute mountain sickness. Lancet I:855.

3. BROWN GV, Howard RJ, Stace, JD, Mitchell GF. (1979) Short term in vitro cultivation of malaria parasites in Papua New Guinea for preparation of biosynthetically labelled parasite antigens. Papua New Guinea Med J 22:37-42.

4. Knopf PM, BROWN GV, Howard RJ, Mitchell GF. (1979) Immunoprecipitation of biosynthetically labelled products in the identification of antigens of murine red cells infected with the protozoan parasite, Plasmodium berghei. Aust J Exp Biol Med Sci 57:603-615.

5. BROWN GV, Battye FL, Howard RJ. (1980) Separation of stages of Plasmodium falciparum infected cells by means of a fluorescence activated cell sorter. Am J Trop Med Hyg 29:1147-1149.

6. Chen P, Lamont G, Elliott T, Kidson C, BROWN G, Mitchell G, Stace J, Alpers M. (1980) Plasmodium falciparum strains from Papua New Guinea: Culture characteristics and drug sensitivity. South East Asian J Trop Med Publ Hlth 11:435-440.

7. BROWN GV, Anders RF, Stace JD, Alpers MP, Mitchell GF. (1981) Immunoprecipitation of biosynthetically-labelled proteins from different Papua New Guinea Plasmodium falciparum isolates by sera from individuals in the endemic area. Parasite Immunol 3:283-298.

8. Howard RJ, BROWN GV, Smith PM, Mitchell GF, Stace JD, Alpers MP, Wember M, Schauer R. (1981) Studies on malaria in Papua New Guinea. Comparison of the surface glycoproteins on red blood cells from infected and uninfected individuals. Parasitology 83:357-372.

9. BROWN GV, Coppel RL, Vrbova H, Grumont RJ, Anders RF. (1982) Plasmodium falciparum: Comparative analysis of erythrocyte stage dependent protein antigens. Exp Parasitol 53:279-284.

10. Mitchell GF, Anders RF, BROWN GV, Handman E, Roberts- Thomson IC, Chapman CB, Forsyth KP, Kahl LP, Cruise KM. (1982) Analysis of infection characteristics and antiparasite immune responses in resistant compared with susceptible hosts. Immunol Revs 61:137-188.

11. BROWN GV, Anders RF, Mitchell GF, Heywood PF. (1982) Target antigens of purified human immunoglobulins which inhibit growth of Plasmodium falciparum in vitro. Nature 297:591-593.

12. Coppel RL, Cowman AF, Kemp DJ, BROWN GV, Anders, R.F. (1983) Recombinant DNA approaches to the study of parasites. Proceedings of the 25th SEAMEO TROPMED Seminar. (Mak JW, Yong HS, eds). Kuala Lumpur Seameo Tropmed Inst Med Research p.159-169.

1513. BROWN GV, Nossal GJV. (1983) World Endemic Disease: Costs and potential fiscal

benefits of medical research. In: Biomedical Institutions, Biomedical Funding and Public Policy. (Fudenberg H ed). Plenum Press, p.115-149.

14. BROWN GV, Anders RF, Knowles G. (1983) Differential effect of immunoglobulin on the in vitro growth of several isolates of Plasmodium falciparum. Infect Immun 39:1228-1235.

15. BROWN GV, Stace JD, Anders RF. (1983). Specificities of antibodies boosted by acute Plasmodium falciparum infection in man. Am J Trop Med Hyg 32:1221-1228.

16. Kemp DJ, Coppel RL, Cowman AF, Saint, R.B, BROWN GV, Anders RF. (1983) Expression of Plasmodium falciparum blood stage antigens in Escherichia coli: detection with antibodies from immune humans. Proc Natl Acad Sci USA 80:3787-3791.

17. Anders RF, BROWN GV, Edwards A. (1983) Characterization of an S antigen synthesized by several isolates of Plasmodium falciparum. Proc Natl Acad Sci USA 80:6652-6656.

18. Coppel RL, Cowman AF, Lingelbach KR, BROWN GV, Saint RB, Kemp DJ, Anders RF. (1983) Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids. Nature 306:751-756.

19. Kemp DJ, Coppel RL, Cowman AF, Saint RB, BROWN GV, Alpers MP, Mitchell GF, Anders RF. (1984) Polyclonal antibodies to monoclonal antigens: antibodies to polypeptides expressed from cloned genes as reagents for the analysis of antigens from Plasmodium falciparum and other parasites. In: Molecular Biology of Host Parasite Interactions. (Agabian B, Eisen H eds.). Alan R Liss, New York, pp 229-238.

20. Coppel RL, Anders RF, BROWN GV, Cowman AF, Lingelbach KR, Saint RB, Mitchell GF, Kemp DJ. (1984) Detection and analysis of Plasmodium falciparum antigens expressed in Escherichia coli. In: Molecular Parasitology August T ed), Academic Press, New York, pp103-115.

21. Gero AM, BROWN GV, O'Sullivan WJ. (1984) Enzymes of pyrimidine biosynthesis in different intra-erythrocytic stages of P.falciparum. In. Malaria. Proceedings of a Conference to Honour Robert H Black. (Bryan JH, Moodie PM, eds) Australian Government Publishing Service, Canberra pp 39-47.

22. BROWN GV, Anders RF, Alpers MP, Mitchell GF. (1984) Parasite diversity and the human antibody response to Plasmodium falciparum. In Malaria. Proceedings of a Conference to Honour Robert H Black. (Bryan JH, Moodie PM, eds). Australian Government Publishing Service, Canberra pp161-167.

23. Anders RF, BROWN GV. (1984) Characterization of an S antigen of several isolates of Plasmodium falciparum growing in continuous culture. In Malaria. Proceedings of a Conference to Honour Robert H. Black. (Bryan JH, Moodie PM eds). Australian Government Publishing Service, Canberra pp 174-179.

24. Coppel RL, BROWN GV, Mitchell GF, Anders RF, Kemp DJ. (1984) Identification of a cDNA clone encoding a mature blood stage antigen of Plasmodium falciparum by immunization of mice with bacterial lysates. EMBO J 3:403-407.

25. Stahl H.D, Coppel RL, BROWN GV, Saint RB, Lingelbach KR, Cowman AF, Anders RF, Kemp DJ. (1984) Differential antibody screening of cloned Plasmodium falciparum sequences expressed in Escherichia coli. Procedure for isolation of defined antigens and analysis of human antisera. Proc Natl Acad Sci USA 81:2456-2460.

26. BROWN GV, Anders RF, Coppel RL, Saint, R.B, Cowman AF, Stahl, H.D, Lingelbach KR, Mitchell GF, Alpers MP, Kemp DJ. (1984) The expression of Plasmodium falciparum bloodstage antigens in Escherichia coli. Phil Trans R Soc Lond B307:179-187.

1627. Kazura JW, Spark R, Forsyth K, BROWN GV, Heywood P, Peters P, Alpers M.

(1984) Parastilogic and clinical features of Bancroftian filariasis in a community in East Sepik Province, Papua New Guinea. Am J Trop Med Hyg 33:1119-1123.

28. Coppel RL, Cowman AF, Anders RF, Bianco, AE, Saint RB, Lingelbach KR, Kemp DJ, BROWN GV. (1984) Immune sera recognize on erythrocytes a Plasmodium falciparum antigen composed of repeated amino acid sequences. Nature 310:789-791.

29. Anders RF, Coppel RL, BROWN GV, Saint RB, Cowman AF, Lingelbach KR, Mitchell GF, Kemp DJ. (1984) Plasmodium falciparum complementary cDNA clones expressed in Escherichia coli encode many distinct antigens. Mol Biol Med 2:177-191.

30. Gero AM, BROWN GV, O'Sullivan WJ. (1984) Pyrimidine de novo synthesis during the life cycle of the intraerythrocytic stage of Plasmodium falciparum. J Parasitol 70:536-541.

31. Cowman AF, Coppel RL, Saint RB, Favaloro J, Crewther PE, Stahl HD, Bianco AE, BROWN GV, Anders RF, Kemp DJ. (1984) The ring-infected erythrocyte surface antigen (RESA) polypeptide of Plasmodium falciparum contains two separate blocks of tandem repeats encoding antigenic epitopes that are naturally immunogenic in man. Mol Biol Med 2:207-221

32. Cowman AF, Saint RB, Coppel RL, BROWN GV, Favoloro J, Crewther PE, Culvenor JG, Bianco AE, Stahl HD, Mitchell GF, Kemp DJ, Anders RF. (1985) Repeat structures in protein antigens of asexual erythrocyte stages of Plasmodium falciparum. In: Modern Approaches to Vaccines: Molecular and Chemical Basis of Resistance to Viral, Bacterial and Parasitic Diseases, (Lerner R and Chanock R eds). Cold Spring Harbor Laboratory. pp.13-18.

33. Stahl HD, Crewther PE, Anders RF, BROWN GV, Coppel RL, Bianco AE, Mitchell GF, Kemp DJ. (1985) Interspersed blocks of repetitive and charged amino acids in a dominant immunogen of Plasmodium falciparum. Proc Natl Acad Sci USA 82:543-547.

34. Cowman AF, Saint RB, Coppel RL, BROWN GV, Anders RF, Kemp DJ. (1985) Conserved sequences flank variable tandem repeats in two S antigen genes of Plasmodium falciparum. Cell 40:775-783.

35. Coppel RL, Saint RB, Stahl HD, Langford CJ, BROWN GV, Anders RF, Kemp DJ. (1985) Plasmodium falciparum: Differentiation of isolates with DNA hybridization using antigen gene probes. Exp Parasitol 60:82-89.

36. Kemp DJ, Corcoran LM, Coppel RL, Stahl HD, Bianco AE, BROWN GV, Anders RF. (1985) Size variation in chromosomes from independent cultured isolates of Plasmodium falciparum. Nature 315:347-350.

37. Saul A, Cooper J, Ingram L, Anders RF, BROWN GV. (1985) Invasion of erythrocytes in vitro by Plasmodium falciparum can be inhibited by a monoclonal antibody directed against an S antigen. Parasite Immunol 7:587-593.

38. Forsyth KP, Spark R, Kazura J, BROWN GV, Peters P, Heywood P, Dissanayake S, Mitchell GF. (1985) A monoclonal antibody based immunoradiometric assay for detection of circulating antigen in Bancroftian filariasis. J Immunol 134:1172-1177.

39. Coppel RL, Favaloro JM, Crewther PE, Burkot TR, Bianco AE, Stahl HD, Kemp DJ, Anders RF, BROWN GV. (1985) A blood stage antigen of Plasmodium falciparum shares determinants with the sporozoite coat protein. Proc Natl Acad Sci USA 82:5121-5125.

40. BROWN GV, Culvenor JG, Crewther PE, Bianco AE, Coppel RL, Saint RB, Stahl HD, Kemp DJ, Anders RF. (1985) Localization of the ring infected erythrocyte surface antigen (RESA) of Plasmodium falciparum in merozoites and ring infected erythrocytes. J Exp Med 162:774-779.

1741. Stahl HD, Kemp DJ, Crewther PE, Scanlon D, Woodrow G, BROWN GV, Bianco

AE, Anders RF, Coppel RL. (1985) Sequence of a cDNA encoding a small polymorphic histidine and alanine rich protein from Plasmodium falciparum. Nucleic Acids Res 13:7837-7846.

42. Anders RF, Shi PT, BROWN GV, Stahl HD, Favaloro JM, Bianco AE, Crewther PE, Coppel RL, Leach, SJ, Kemp DJ. (1985) Immune recognition of repeat structures in malaria antigens. In: The Immune Recognition of Protein Antigens. (Laver WG, Air GM eds). Current Communications in Molecular Biology, Cold Spring Harbour Laboratory, pp193-197.

43. Anders RF, BROWN GV, Coppel RL, Stahl HD, Bianco AE, Favaloro JM, Crewther PE, Culvenor JG, Kemp DJ. (1985) Potential vaccine antigens of the asexual blood stages of P.falciparum. In: Develop Biol Standards, Vol.62, Diagnostics and Vaccines for Parasitic Diseases, (Tiru M, Hennessen W, eds). S Karger, Basel. pp.81-89.

44. Coppel RL, Cowman AF, Kemp DJ, BROWN GV, Anders RF. (1985) Recombinant DNA and Parasitology. In: Applications of Genetic Engineering to Research in Tropical Disease Pathogens with Special Reference to Plasmodia. A Laboratory Manual of Selected Techniques. (Paynim S, Wilairat P, Yuthavong Y, eds). UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, pp.11-25.

45. BROWN GV, Kemp DJ, Coppel RL, Crewther PE, Culvenor JG, Anders RF. (1986) Antigens of the asexual stages of Plasmodium falciparum. International Symposium on Malaria, Rio de Janeiro, Brasil. Mem Int Oswaldo Cruz. Vol. 81, Suppl. II, pp.63-68.

46. Coppel RL, BROWN GV, Langford CJ, Bianco AE, Stahl HD, McIntyre P, Corcoran LM, Woodrow G, Favaloro J, Crewther PE, Mitchell GF, Anders RF, Kemp DJ. (1986) Production of asexual blood stage antigens. In: Proceedings of the Asia and Pacific Conference on Malaria: Practical Considerations on Malaria Vaccines and Clinical Trials, Hawaii (Siddiqui W ed). University of Hawaii, pp 293-308.

47. Coppel RL, Saint RB, Cowman AB, Culvenor JG, BROWN GV, Anders RF, Kemp DJ. (1986) Soluble antigens of the asexual blood stages of Plasmodium falciparum. In: Proceedings of the Asia and Pacific Conference on Malaria: Practical Considerations on Malaria Vaccines and Clinical Trials, Hawaii (Siddiqui W ed). University of Hawaii, pp185-193.

48. Bianco AE, Battye FL, BROWN GV, (1986) Plasmodium falciparum: Rapid quantification of parasitemia in fixed malaria cultures by flow cytometry. Exp Parasit 62:275-282.

49. Kemp DJ, Coppel RL, Stahl HD, Bianco AE, Corcoran LM, McIntyre P, Langford CJ, Favaloro JM, Crewther PE, BROWN GV, Mitchell GF, Culvenor JG, Anders RF. (1986) Genes for antigens of Plasmodium falciparum. Parasitology 91:S83-108.

50. Stahl HD, Bianco AE, Crewther PE, Anders RF, Kyne AP, Coppel RL, Mitchell GF, Kemp DJ, BROWN GV. (1986) Sorting large numbers of clones expressing Plasmodium falciparum antigens in Escherichia coli by differential antibody screening. Mol Biol Med 3:351-368.

51. Anders RF, Shi PT, Scanlon DB, Leach SJ, Coppel RL, BROWN GV, Stahl HD, Kemp DJ. (1986) Antigenic repeat structures in proteins of Plasmodium falciparum. In: Synthetic Peptides as Antigens. CIBA Foundation Symposium 119, (Porter R, Whelan J, eds). John Wiley and Sons, Chichester. pp 164-175.

52. Corcoran LM, Forsyth KP, Bianco AE, BROWN GV, Kemp DJ. (1986) Chromosome size polymorphisms in Plasmodium falciparum can involve deletions and are frequent in natural parasite populations. Cell 44:87-95.

1853. Crewther PE, Bianco AE, BROWN GV, Coppel RL, Stahl HD, Kemp DJ, Anders RF.

(1986) Affinity purification of human antibodies directed against cloned antigens of Plasmodium falciparum J Immunol Meths 86:257-264.

54. Coppel RL, Culvenor JG, Bianco AE, Crewther PM, Stahl HD, BROWN GV, Anders RF, Kemp DJ. (1986) Variable antigen associated with the surface of erythrocytes infected with mature stages of Plasmodium falciparum. Mol Biochem Parasitol 20:265-277.

55. BROWN GV, Anders RF, Thomas L, Hoogland V, Knowles G, Davidson W. (1986). Measurement of antibody response to individual cloned antigens of Plasmodium falciparum. Papua New Guinea Med J 29:81-86.

56. Anders RF, BROWN GV, Coppel RL, Kemp DJ. (1986) Repeat structures in malaria antigens. Papua New Guinea Med J 29:87-93.

57. BROWN GV. (1986) Chemoprophylaxis of malaria. Med J Aust 144:696-706.58. BROWN GV, Nossal GJV. (1986) Malaria - yesterday, today and tomorrow.

Perspectives in Biol Med 30:65-76.59. Stahl HD, Bianco AE, Crewther PE, Burkot T, Coppel RL, BROWN GV, Anders RF,

Kemp DJ. (1986). An asparagine rich protein from blood stages of Plasmodium falciparum, shares determinants with sporozoites. Nucleic Acid Res 14:3089-3102.

60. Kemp DJ, Corcoran LM, Forsyth KP, Coppel RL, Stahl HD, Bianco AE, BROWN GV, Anders RF. (1986) Genes and chromosomes of Plasmodium falciparum. In: Molecular strategies of parasitic invasion. UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 42 (Agabian N, Goodman H, Noguiera N, eds). Alan R Liss Inc, New York. pp 29-36.

61. Collins WE, Anders RF, Pappaioanou M, Campbell GH, BROWN GV, Kemp DJ, Coppel RL, Skinner JC, Andrysiak PM, Favaloro JM, Corcoran LM, Broderson JR, Mitchell GF, Campbell CC. (1986) Immunization of Aotus monkeys with recombinant proteins of an erythrocyte surface antigen of Plasmodium falciparum. Nature 323:259-262.

62. Bianco AE, Favaloro JM, Burkot TR, Culvenor JG, Crewther PE, BROWN GV, Anders RF, Coppel RL, Kemp DJ. (1986) A repetitive antigen of Plasmodium falciparum that is homologous to heat shock protein 70 of Drosophila melanogaster. Proc Natl Acad Sci USA 83:8713-8717.

63. BROWN GV. (1986) Prospects for a vaccine against malaria. Med J Aust 144:703-704.

64. Anders RF, BROWN GV, Coppel RL, Kemp DJ. (1986). Induction of protective immunity to malaria. Leprosy Rev 57:245-253.

65. Favaloro JM, Coppel RL, Corcoran LM, Foote SJ, BROWN GV, Anders RF, Kemp DJ. (1986) Structure of the RESA gene of Plasmodium falciparum. Nucleic Acids Res 14:8265-8277.

66. Culvenor JG, Langford CJ, Crewther PE , Saint RB, Coppel RL, Kemp DJ, Anders RF, BROWN GV. (1987) Plasmodium falciparum: identification and localization of a knob protein antigen expressed by a cDNA clone. Exp Parasitol 63:58-67.

67. McIntyre P, Coppel RL, Smith DB, Stahl HD, Corcoran LM, Langford CJ, Favaloro JM, Crewther PE, BROWN GV, Mitchell GF, Anders RF, Kemp DJ. (1987) Expression of parasite antigens in Escherichia coli. In: Parasitology - Quo Vadit? (Howell MJ ed). Australian Academy of Science, pp 59-67. Also published in Int J Parasitol 17:59-67.

68. Anders RF, Barzaga N, Shi PT, Scanlon D, Brown LE, Thomas LM, BROWN GV, Stahl HD, Coppel RL, Kemp DJ. (1987) Repetitive sequence in malaria antigens. In: Molecular Strategies of Parasitic Invasion. UCLA Symposium on Molecular

19and Cellular Biology, New Series, Vol. 42 (Agabian N, Goodman H, Noguiera N eds). Alan R. Liss Inc, New York. pp 333-342.

69. Bianco AE, Culvenor JG, Coppel RL, Crewther PE, McIntyre P, Favaloro JM, BROWN GV, Kemp DJ, Anders RF. (1987) A putative glycophorin binding protein is secreted from schizonts of Plasmodium falciparum. Mol Biochem Parasitol 23:91-102.

70. Coppel RL, Anders RF, Pappaioanou, M, Campbell GH, BROWN GV, Kemp DJ, Skinner JC, Andrysiak, PM, Favaloro JM, Corcoran LM, Broderson JR, Mitchell GF, Campbell CC, Collins WE. (1987) Fragments of the RESA protein produced in Escherichia coli protect monkeys against Plasmodium falciparum infection. In: Vaccines '87. (Chanock R, Brown F, Lerner R, Ginsberg H eds). Cold Spring Harbor Laboratory pp 97-102.

71. Anders RF, Murray LJ, Thomas LM, Davern KM, BROWN GV, Kemp DJ. (1987) Structure and function of candidate vaccine antigens in Plasmodium falciparum. Biochem Soc Symposium 53:103-114.

72. Triglia T, Stahl HD, Crewther PE, Scanlon D, BROWN GV, Anders RF, Kemp DJ. (1987) The complete sequence of the gene for the knob-associated histidine-rich protein. EMBO J 6:1413-1419.

73. Saint RB, Coppel RL, Cowman AF, BROWN GV, Shi PT, Barzaga N, Kemp DJ, Anders RF. (1987) Changes in repeat number, sequence and reading frame in S-antigen genes of Plasmodium falciparum. Mol Cell Biol 7:2968-2973.

74. BROWN GV. (1987) Personal protection against malaria: current strategies and prospects for vaccines. In: Immunization in Australia, Proceedings of the First National Conference, Canberra. Public Health Association of Australia and New Zealand. pp 149-158.

75. Coppel RL, Bianco AE, Crewther PE, Anders RF, Kemp DJ, BROWN GV. (1987) A cDNA clone expressing a rhoptry protein of Plasmodium falciparum. Mol Biochem Parasitol 25:73-81.

76. Brown H, Kemp DJ, Barzaga N, BROWN GV, Anders RF, Coppel RL. (1987) Sequence variation in S-antigen genes of Plasmodium falciparum. Mol Biol Med 4:365-376.

77. Collins WE, Pappaioanou M, Anders RF, Campbell GH, BROWN GV, Kemp DJ, Broderson JR, Coppel RL, Skinner JC, Procell PM, Favaloro, JM, Corcoran LM, Ma NSF, Mitchell GF, Campbell CC. (1988) Immunization trials with the ring-infected erythrocyte surface antigen of Plasmodium falciparum in owl monkeys (Aotus vociferans). Am J Trop Med Hyg 38:268-282.

78. Bianco AE, Crewther PE, Coppel RL, Stahl HD, Kemp DJ, Anders RF, BROWN GV. (1988) Patterns of antigen expression in asexual blood stages and gametocytes of Plasmodium falciparum. Am J Trop Med Hyg 38:258-267.

79. Peterson MG, Coppel RL, McIntyre P, Langford CJ, Woodrow G, BROWN GV, Anders RF, Kemp DJ. (1988) Variation in the precursor to the major merozoite surface antigens of Plasmodium falciparum. Mol Biochem Parasitol 27:291-302.

80. Peterson MG, Crewther PE, Coppel RL, Thompson JK, Bianco AE, BROWN GV, Anders RF, Kemp DJ. (1988) A second antigenic heat shock protein of Plasmodium falciparum. DNA 7:71-78.

81. Anders RF, Coppel RL, BROWN GV, Kemp DJ. (1988) Antigens with repeated amino acid sequences from the asexual blood stages of Plasmodium falciparum. Prog Allergy 41:148-172.

82. Coppel RL, Crewther PE, Culvenor JG, Perrin LH, BROWN GV, Kemp DJ, Anders RF. (1988) Variation in p126 a parasitophorous vacuole antigen of Plasmodium falciparum. Mol Biol Med 5:155-166.

2083. Smythe JL, Coppel RL, BROWN GV, Kemp DJ, Anders, R.F. (1988) Identification

of two integral membrane proteins of Plasmodium falciparum. Proc Natl Acad Sci USA 85:5195-5199.

84. Lustigman S, Anders RF, BROWN GV, Coppel RL. (1988) A component of an antigenic rhoptry complex of Plasmodium falciparum is modified after merozoite invasion. Mol Biochem Parasitol 30:217-224.

85. Southwell B, BROWN GV, Forsyth KP, Smith T, Philip G, Anders RF. (1989) Field applications of agglutination and cytoadherence assays with Plasmoidum falciparum from Papua New Guinea. Trans Roy Soc Trop Med Hyg 83:464-469.

86. BROWN GV. (1988) Tropical Health Presentation. In: Proceedings and Recommendations Papua New Guinea/Australia Colloquium. International Development Program of Australian Universities and Colleges. James Cook University, Townsville, pp 116-120.

87. BROWN GV, Biggs, B-A. (1989) Current strategies for protection against malaria and prospects for vaccines. In: A textbook of Preventive Medicine (McNeil J, King R, Jennings G, Powles J, eds). Edward Arnold, Melbourne pp 91-97.

88. Biggs BA, Kemp DJ, BROWN GV. (1989) Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro. Proc Natl Acad Sci USA. 86:2428-2432.

89. Biggs BA, Culvenor JG, Ng JS, Kemp DJ, BROWN GV. (1989) Plasmodium falciparum: Cytoadherence of a knobless clone. Exp Parasitol 69:189-197.

90. Forsyth KP, Philip G, Smith T, Kum E, Southwell B, BROWN GV. (1989) Diversity of antigens expressed on the surface of erythrocytes infected with mature Plasmodium falciparum parasites in Papua New Guinea. Am J Trop Med Hyg 41:259-265.

91. Lustigman S, Anders RF, BROWN GV, Coppel RL. (1990) The mature-parasite-infected erythrocyte surface antigen (MESA) of Plasmodium falciparum associates with the erythrocyte membrane skeletal protein, band 4.1. Mol Biochem Parasitol 38:261-270.

92. Foote SJ, Thompson JK, Marshall V, Cowman AF, Biggs BA, BROWN GV, Kemp DJ. (1990) The multidrug resistance gene of P.falciparum; does it mediate chloroquine resistance? In: Parasites: Molecular Biology, Drug and Vaccine Design. UCLA Symposium on Molecular and Cellular Biology, New Series, Vol 130 (Agabian N, Cerami A, eds). Alan R Liss Inc, New York, pp.325-334.

93. Anders RF, BROWN GV. (1990) Development of a vaccine against the asexual blood stages of malaria. In: New Generation Vaccines (Woodrow GC, Levine MM. eds). Marcel Dekker, New York, pp 491-520.

94. Anders RF, Smythe JA, Barzaga NG, Forsyth KP, Brown HJ, Crewther PE, Thomas LM, Coppel RL, Culvenor JG, BROWN GV. (1990) Antigenic diversity of the asexual blood stages of Plasmodium falciparum. In: Frontiers of Infectious Diseases, New Strategies in Parasitology (McAdam KPW ed). Vol II. Churchill Livingston, Oxford, pp 19-36.

95. Shirley MW, Biggs BA, Forsyth KP, Brown HJ, Thompson JK, BROWN GV, Kemp DJ. (1990). Chromsome 9 from independent clones and isolates of Plasmodium falciparum undergoes subtelomeric deletions with similar breakpoints in vitro. Mol Biochem Parasitol 40:137-146.

96. BROWN GV, Biggs BA. (1990) Malaria: advice to travellers. Aust Family Physician 19:177-192.

97. Biggs BA, Gooze L, Wycherley K, Wilkinson D, Boyd AW, Forsyth KP, Edelman L, BROWN GV, Leech LH. (1990) Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36. J Exp Med 171:1883- 1892.

2198. Collins WE, Anders RF, Ruebush II TK, Kemp DJ, Woodrow GC, Campbell GH,

BROWN GV, Irving DO, Goss N, Filipski VK, Coppel RL, Broderson JR, Thomas LM, Pye D, Skinner JC, Wilson C, Stanfill PS, Procell PM. (1991) Immunization of owl monkeys with the ring-infected erythrocyte surface antigen of Plasmodium falciparum. Am J Trop Med Hyg 44:34-41.

99. BROWN GV, Mitchell GF. (1991) The immunology of parasitism. In: Encyclopaedia of Human Biology, Vol.4. (Dulbecco R, ed). Academic Press, San Diego, pp 385-390.

100. Biggs, BA, Gooze L, Wycherley K, Wollish W, Southwell B, Leech JH, BROWN GV. (1991) Antigenic variation of Plasmodium falciparum. Proc Natl Acad Sci USA 88:9171-9174.

101. Erlich JH, Rosenfeld JV, Fuller A, BROWN GV, Wodak J, Tress BP. (1992). Acute intramedullary spinal cord abscess: case report. Surg Neurol 38:287-290.

102. Kemp DJ, Thompson J, Barnes DA, Triglia T, Karamalis F, Petersen C, BROWN GV, Day KP. (1992) A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence. Proceedings of the IV International Congress on Malaria and Babesiosis. Memorias do Instituto Oswaldo Cruz 87:85-89.

103. Biggs BA, Anders RF, Dillon HE, Davern KM, Martin M, Petersen C, BROWN GV. (1992) Adherence of infected erythrocytes to venular endothelium selects for antigenic variants of Plasmodium falciparum. J Immunol 149:2047-2054.

104. Roberts DJ, Biggs BA, BROWN GV, Newbold CI. (1993) Protection, pathogenesis and phenotypic plasticity in Plasmodium falciparum malaria. Parasitol Today 9:281-286.

105. BROWN GV. (1993) Chemoprophylaxis in malaria. Med J Aust 159:187-196.106. Mulhall BP, BROWN GV. (1993) Perspectives on tropical health. Med J Aust

158:442-443.107. Day KP, Karamalis F, Thompson J, Barnes DA, Petersen C, Brown H, BROWN GV,

Kemp DJ. (1993) Genes necessary for expression of a virulence determinant and for transmission of Plasmodium falciparumare located on a 0.3-megabase region of chromosome 9. Proc Natl Acad Sci USA 90:8292-8296.

108. Roberts DJ, Biggs BA, BROWN GV, Newbold CI. (1993) Protection, pathogenesis and phenotypic plasticity in Plasmodium falciparum malaria. Reply. Parasitol Today 10, 64-65.

109. Chaiyaroj SC, Thompson JK, Coppel RL, BROWN GV. (1994) Gametocytogenesis occurs in Plasmodium falciparum isolates carrying a chromosome 9 deletion. Mol Biochem Parasitol 63:163-166.

110. Reeder JC, Rogerson SJ, Al-Yaman F, Anders RF, Coppel RL, Novakovic, S, Alpers MP, BROWN GV. (1994) Diversity of agglutinating phenoytpe, cytoadherence, and rosette-forming characteristics of Plasmodium falciparum isolates from Papua New Guinea children. Am J Trop Med Hyg 51:45-55.

111. Chaiyaroj SC, Coppel RL, Magowan C, and BROWN GV. (1994) A Plasmodium falciparum isolate with a chromosome 9 deletion expresses a trypsin resistant cytoadherence molecule. Mol Biochem Parasitol 67:21-30.

112. Rogerson SJ, Reeder JC, Al-Yaman F, BROWN GV, (1994) Sulfated glycoconjugates as disruptors of Plasmodium falciparum erythrocyte rosettes. Am J Trop Med Hyg 51:198-203.

113. Pain M, Davis S, BROWN G. (1994) Severe forms of infection with Angiostrongylus cantonensis acquired in Australia and Fiji. Aust NZ J Med 24:415-416

114. Chaiyaroj SC, Coppel RL, Novakovic S, BROWN GV. (1994) Multiple ligands for cytoadherence are present on the surface of Plasmodium falciparum infected erythrocytes. Proc Natl Acad Sci USA 91:10805-10808.

22115. Rogerson S, Biggs BA, BROWN GV. (1994) Chemoprophylaxis and treatment of

malaria. Family Physician 23:1696-1709.116. BROWN GV. (1995) Biotechnology and health. Lancet 344:1425.117. Rogerson SJ, Chaiyaroj SC, Ng K, Reeder JC, BROWN GV. (1995).

Chondroitin sulfate A is a cell surface receptor for Plasmodium falciparum-infected erythrocytes. J Exp Med 182:15-20.

118. BROWN GV. (1995) Application of molecular biology to clinical medicine. Proceedings of the Scientific Workshop of the 7th National Conference. The Indonesian Society of Internal Medicine. (Samual AR, Nelwan RHH, Tendean-Wenas N, Lefrandt R, Pandelaki K, eds). pp 1-6.

119. Sturchler D, Berger R, Rudin C, Just M, Saul A, Rzepczyk G, BROWN G. Anders R, Coppel R, Woodrow D, Pye F, Sorenson F, Gillessen D, Matile H, Reber-Liske R. (1995) Safety, immunogenicity, and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults. Am J Trop Med Hyg 53:423-431.

120. BROWN GV, Davern KM, Novakovic SB, Rogerson SJ, Reeder JC. (1996) The association between antigenicity and phenotype of parasite dependent molecules on the surface of Plasmodium falciparum infected erythrocytes which form rosettes. Protozol Abstracts 20:1-4.

121. Rogerson SJ, Beck H-P, Al-Yaman F, Currie B, Alpers MP, BROWN GV. (1996) Disruption of erythrocyte rosettes and agglutination of erythrocytes infected with Plasmodium falciparum by the sera of Papua New Guineans. Trans Roy Soc Trop Med Hyg 90:80-84.

122. BROWN GV, Rogerson SJ. (1996) Preventing cytoadherence of infected erythrocytes to endothelial cells and noninfected erythrocytes. In: Malaria Vaccine Development: A Multi-Immune Response Approach. (Hoffman S, ed). ASM Press, Washington, pp145-166.

123. Chaiyaroj SC, Angkasekwinai P, Buranakiti A, Looareesuwan S, Rogeson SJ, BROWN GV. (1996) Cytoadherence characteristics of Plasmodium falciparum isolates from Thailand: evidence for chondroitin sulfate A as a cytoadherence receptor. Am J Trop Med Hyg 55:76-80.

124. Cooke BM, Rogerson SJ, BROWN GV, Coppel RL. (1996). Adhesion of malaria-infected red blood cells to chondroitin sulfate A under flow conditions. Blood 88:4040-4044.

125. Reeder JC, BROWN GV. (1996). Antigenic variation and immune evasion in Plasmodium falciparum malaria. Immunol. Cell Biol 74:546-554.

126. Conn, J, Colman, P, BROWN G, Street A, Bate K. (1996) Nephrogenic diabetes insipidus associated with foscarnet - a case report. J Antimicrobial Chemo 37:1179-1181.

127. Rogerson SJ, Novakovic S, Cooke BM, BROWN GV. (1997) Plasmodium falciparum: infected erythrocytes adhere to the proteoglycan thrombomodulin in static and flow based systems. Exp Parasitol 86:8-18.

128. Rogerson SJ, BROWN GV. (1997). Chondroitin sulphate A as an adherence receptor for Plasmodium falciparum infected erythrocytes. Parasitol Today 13:70-75.

129. Reeder JC, Davern KM, Baird JK, Rogerson SJ, BROWN GV. (1997) The age-specific prevalence of Plasmodium falciparum in migrants to Irian Jaya is not attributable to agglutinating antibody repertoire. Acta Tropica 65:163-173.

130. Crabb BS, Cooke BM, Reeder JC, Waller RF, Caruana SR, Davern KM, Wickham ME, BROWN GV, Coppel RL, Cowman AF. (1997) Targeted gene disruption shows that knobs enable malaria-infected cells to cytoadhere under physiological shear stress. Cell 89:287-296.

23131. Jenkin GA, Ritchie SA, Hanna JN, BROWN GV. (1997) Airport malaria in Cairns.

Med J Aust 166:307-308.132. Jenkin G, Woolley IJ, BROWN GV, Richards MJ. (1997) Postpartum epidural

abscess due to group B Streptococcus. Clin Infect Dis 25:1249.133. BROWN GV, Mitchell GF. (1997) Immunology of parasitism. In: Encyclopedia of

Human Biology, Second Edition, Vol 4. (Dulbecco R, ed). Academic Press. pp 761-766.

134. BROWN GV. (1997) Fighting malaria. Brit Med J 314:1707-1708.135. Beeson JG, Chai W, Rogerson SJ, Lawson AM, BROWN GV. (1998) Inhibition of

binding of malaria-infected erythrocytes by a tetradecasaccharide fraction from chondroitin sulfate A. Infect Immun 66:3397-3402.

136. Coppel RL, BROWN, GV. Nussenzweig, V. (1998) Adhesive proteins of the malaria parasite. Curr Opin Microbiol 1:472-481.

137. Hellard ME, Street AC, Johnson PD, Popovic E, BROWN GV. (1998) Detection of an aberrant motile larval form in the brain of a patient with neurocysticercosis. Clin Infect Dis 27:391-393.

138. Hellard M, Street A, BROWN GV, Hoy JF. (1998) Pyomyositis in HIV-infected patients: a difficult diagnosis. Venereology 11:39-40

139. Reeder JC, Cowman AF, Davern KM, Beeson JG, Thompson JK, Rogerson SJ, BROWN GV. (1999) The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P.falciparum erythrocyte membrane protein 1. Proc Natl Acad Sci USA 96:5198-5202.

140. Saul A, Lawrence G, Smillie A, Rzepczyk, CM, Reed C, Taylor D, Anderson K, Stowers A, Kemp R, Allworth A, Anders RF, BROWN GV, Pye D, Schoofs P, Irving DO, Dyer SL, Woodrow GC, Briggs WRS, Reber R, Sturchler D. (1999) Human phase I vaccine trials of 3 recombinant asexual stage malaria antigens with Montanide ISA720 adjuvant. Vaccine 17:3145-3159.

141. Beeson JG, BROWN GV, Molyneux ME, Mhango C, Dzinjalamala F, Rogerson SJ. (1999) Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties. J Infect Dis 180:464-472.

142. BROWN GV. (1999) Progress in the development of malaria vaccines: context and constraints. Parasitologia 41:429-432.

143. BROWN GV. (1999). The need to ‘maintain the rage’. Parasitologia 41: 510.144. Genton B, Al-Yaman F, Anders R, Saul A, BROWN G, Pye D, Irving DO, Briggs

WR, Mai A, Ginny M, Adiguma T, Rare L, Giddy A, Reber-Liske R, Stuerchler D, Alpers, MP. (2000) Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea. Vaccine 18:2504-2511.

145. Beeson JG, Rogerson SJ, Cooke BM, Reeder JC, Chai W, Lawson AM, Molyneux

ME, BROWN GV. (2000) Adhesion of Plasmodium falciparum-infected erythrocytes to hyaluronic acid in placental malaria. Nature Med 6:86-90.

146. Reeder JC, Hodder AN, Beeson JG, BROWN GV. (2000) Identification of glycosaminoglycan binding domains in Plasmodium falciparum erythrocyte membrane protein 1 of a chondroitin sulfate A-adherent parasite. Infect Immun 68:3923-3926.

147. BROWN GV, Beck HP, Molyneux M, Marsh K. (2000) Molecular approaches to epidemiology and clinical aspects of malaria. Parasitol Today 16: 448-451.

148. Chai W, Beeson JG, Kogelberg H, BROWN GV, Lawson AM. (2001) Inhibition of adhesion of Plasmodium falciparum-infected erythrocytes by structurally defined hyaluronic acid dodecasaccharides. Infect Immun 69:420-425

24149. Beeson JG, Winstanley PA, McFadden GI, BROWN GV. (2001) New agents to

combat malaria. Nature Med 7:149-150.150. Noviyanti R, GV BROWN, Wickham ME, Duffy MF, Cowman AF, Reeder JC. (2001)

Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion. Mol Biochem Parasitol 114:227-237.

151. Biggs BA, BROWN GV. (2001) Malaria. In: Principles and Practice of Clinical Parasitology (Gillespie SH, Pearson RD, eds). John Wiley & Sons Ltd, UK pp. 53-98.

152. BROWN GV, Yung A. (2001) Infectious Diseases: A Global Perspective. In: Infectious Diseases. A Clinical Approach. (Yung A, McDonald M, Spelman D, Street A, Johnson P, Eds). pp 39-42.

153. BROWN GV. (2001) Malaria. In: Infectious Diseases. A Clinical Approach. (Yung A, McDonald M, Spelman D, Street A, Johnson P, Eds). pp 251-263.

154. BROWN GV. (2001) Illnesses contracted abroad. In: An Introduction to Symptoms and Signs in General Medicine. (Toghill P, Gray D, Eds). Arnold, UK, pp 232-237.

155. O’Brien D, Tobin S, BROWN GV, Torresi J. (2001) Fever in returned travellers: Review of hospital admissions for a 3-year period. Clin Infect Dis 33:603-609.

156. Beeson JG, Reeder JC, Rogerson SR, BROWN GV. (2001) Parasite adhesion and immune evasion in placental malaria. Trends Parasitol 17:331-337.

157. MacIntyre CR, Empson M, Boardman C, Sindhusake D, Lokan J, BROWN GV. (2001) Risk factors for colonization with vancomycin-resistant enterococci in a Melbourne hospital. Infect Control Hospital Epidemiol. 22:624-629.

158. BROWN GV, Good MF. (2002). Prospects for a vaccine against malaria. Internal Med J 32, 129-131.

159. Duffy MF, BROWN GV, Basuki W, Krejany EO, Noviyanti R, Cowman AF, Reeder JC. (2002) Transcription of multiple var genes by individual, trophozoite stage Plasmodium falciparum cells expressing a chrondroitin sulfate A binding phenotype. Mol Microbiol. 43:1285-1293.

160. Genton B, Betuela I, Felger I, Al-Yaman F, Anders RF, Saul A, Rare L, Baisor M, Lorry K, BROWN GV, Pye D, Irving DO, Smith TA, Beck H-P, Alpers MP. (2002) A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a Phase 1-2b trial in Papua New Guinea. J Infect Dis 185:820-827.

161. Beeson JG, BROWN GV. (2002) Pathogenesis of Plasmodium falciparum malaria: the roles of parasite adhesion and antigenic variation. Cell Mol Life Sci 59:258-271.

162. BROWN GV. (2002) Malaria – A global crisis. In: Orphan Vaccines - Bridging the Gap. (Brown F, Gust I, Eds). Dev Biol Basel 110:37-43.

163. BROWN GV (2002) Importation of diseases of human significance. Microbiol Aust. May p34.

164. O'Brien D, BROWN GV (2002) Fever in returned travellers: an Australian perspective. Microbiol Aust. May pp10-11.

165. Beeson JG, Rogerson SJ, BROWN GV. (2002) Evaluating specific adhesion of Plasmodium falciparum-infected erythrocytes to immobilized hyaluronic acid with comparison to binding of mammalian cells. Int J Parasitol 32: 1245-1252.

166. BROWN GV, Reeder JC. (2002) Malaria vaccines. Med J Aust 177: 230-231.167. MacIntyre CR, Kainer MA, BROWN GV. (2003). A randomised, clinical trial

comparing the effectiveness of hospital and community-based reminder systems for increasing uptake of influenza and pneumococcal vaccine in hospitalised patients aged 65 years and over. Gerontology 49:33-40.

168. Leder K, Sundararajan V, Weld L, Pandey P, BROWN G, Torresi J, GeoSentinel Surveillance Group. (2003) Respiratory tract infections in

25travellers: a review of the GeoSentinel surveillance network. Clin Infect Dis 36:399-406.

169. Duffy MF, Reeder JC, BROWN GV. (2003) Regulation of antigenic variation in Plasmodium falciparum: censoring freedom of expression? Trends Parasitol 19:121-123.

170. Sung V, O’Brien DP, Matchett E, BROWN GV, Torresi J. (2003) Dengue fever in travellers returning from South East Asia. J Travel Med. 10: 208-213.

171. Genton B, Al-Yaman F, Betuela I, Anders RF, Saul Al, Baea K, Mellombo M, Taraika, J. BROWN GV, Pye D, Irving DO, Felger I, Beck H-P, Smith TA, Alpers MP. (2003) Safety and immunogenicity of a three-component blood-stage malaria vaccine (MSP1, MSP2, RESA) against Plasmodium falciparum in Papua New Guinean children. Vaccine 22:30-41

172. MacIntyre CR, Goebel K, BROWN GV, Skull S, Starr M, Fullinfaw RO. (2003) A randomised controlled clinical trial of the efficacy of family based direct observation of anti-tuberculous treatment in an urban, developed-country setting. Intl J Tuberc Lung Dis 7:848-854

173. Noviyanti R, BROWN GV. (2003) Phenotypic switching and var gene transcription in Plasmodium falciparum Adv Exp Med Biol 531:149-159

174. Beeson JG, Mann EJ, Elliott SR, Lema VM, Tadesse E, Molyneux ME, BROWN GV, Rogerson SJ. (2004) Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes and adhesion inhibitory antibodies are associated with placental malaria and have overlapping and distinct targets. J Infect Dis.189:540-551.

175. Beeson JG, BROWN GV. (2004) Plasmodium falciparum-infected erythrocytes demonstrate dual specificity for adhesion to hyaluronic acid and chondroitin sulfate A and have distinct adhesive properties. J Infect Dis 189: 169-179

176. BROWN GV, Torresi J, Flint S. (2004) Delayed onset of malaria – implications for chemoprophylax. N Engl J Med 350, 195-196. (Letter)

177. Leder K, Black J, O’Brien D, Greenwood Z, Kain KC, Schwartz E, BROWN G, Torresi J. (2004) Malaria in travellers: a review of the GeoSentinel Surveillance Network. Clin Infect Dis 39:1104-1112.

178. Elliott JH, O’Brien D, Leder K, Kitchener S, Schwartz E, Weld L, BROWN GV, Kain KC, Torresi J. (2004) Imported Plasmodium vivax malaria: demographic and clinical features in nonimmune travellers. J Travel Med 11:213-219.

179. Buising KL, Thursky KA, Black JF, BROWN GV. (2004). Are the Australian guidelines asking too much of the Pneumonia Severity Index (PSI). Med J Aust 180:486-487.

180. MacIntyre CR, Goebel K, BROWN GV. (2005) Patient knows best: blinded assessment of non-adherence with antituberculous therapy by physicians, nurses, and patients compared with urine drug levels. Prev Med 40:41-45.

181. Elliott SR, Duffy MF, Byrne TJ, Beeson JG, Mann EJ, Wilson DW, Rogerson SJ, BROWN GV. (2005) Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum infected erythrocytes are associated with transcription of var2csa. Infect Immun 73:2848-2856.

182. Duffy MF, Byrne TJ, Elliott SR, Wilson DW, Rogerson SJ, Beeson JG, Noviyanti R, BROWN GV. (2005) Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype. Mol Micro 56:774-788.

183. Elliott SR, Brennan AK, Beeson JG, Tadesse E, Molyneux ME, BROWN GV, Rogerson SJ. (2005). Placental malaria induces variant-specific antibodies of the cytophilic subtypes immunoglobulin G1 (IgG1) and IgG3 that correlate with adhesion inhibitory activity. Infect Immun. 73:5903-5907.

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26184. Buising KL, Thursky KA, Bak N, Skull S, Street A, Presneill JJ, Cade JF, BROWN

GV. (2005) Antibiotic prescribing in response to bacterial isolates in the Intensive Care Unit. Anaesth Intensive Care 33: 571-577.

185. Beeson JG, Mann EJ, Byrne TJ, Caragounis A, Elliott SR, BROWN GV, Rogerson SJ. (2006) Antigenic differences and conservation among placental Plasmodium falciparum-infected erythrocytes and acquisition of variant-specific and cross-reactive antibodies. J Infect Dis. 193:721-730.

186. Thursky KA, Buising KL, Bak N, MacGregor L, Street AC, MacIntyre CR, Presneill JJ, Cade JF, BROWN GV. (2006) Reduction of broad-spectrum antibiotic use with computerized decision support in an intensive care unit. Intl J Quality Hlth Care 18:224-231.

187. Buising KL, Thursky KA, Black JF, MacGregor L, Street AC, Kennedy MP, BROWN GV. (2006) A prospective comparison of severity scores for identifying patients with severe community acquired pneumonia: reconsidering what is meant by severe pneumonia. Thorax 61:419-424.

188. Duffy MF, Maier AG, Byrne TJ, Marty AJ, Elliott SR, O’Neill MT, Payne PD, Rogerson SJ, Cowman AF, Crabb BS, BROWN GV. (2006) VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum. Mol Biochem Parasitol 148:117-124.

189. O’Brien DP, Leder K, Matchett E, BROWN GV, Torresi J. (2006) Illness in returned travelers and immigrants/refugees: the 6-year experience of two Australian infectious diseases unit. J Travel Med 13:145-152.

190. Leder K, Tong S, Weld L, Kain KC, Wilder-Smith A, von Sonnenburg F, Black J, BROWN GV, Torresi J, GeoSentinel Surveillance Network. (2006) Illness in travelers visiting friends and relatives: a review of the GeoSentinel Network. Clin Infect Dis 43:1185-1193.

191. Duffy MF, Caragounis A, Noviyanti R, Kyriacou HM, Choong EK, Boysen K, Healer J, Rowe JA, Molyneux ME, BROWN GV, Rogerson SJ. (2006) Transcribed var genes associated with placental malaria in Malawian women. Infect Immun 74:4875-4883.

192. Skull SA, Andrews RM, Byrnes GB, Kelly HA, Nolan TM, BROWN GV, Campbell DA. (2007) Pneumococcal polysaccharide vaccine may not prevent hospitalization for pneumonia in elderly individuals. Clin Infect Dis 44:617.

193. Gautret P, Schwartz E, Shaw M, Soula G, Gazin P, Delmont J, Parola P, Soavi MJ, Matchett E, BROWN G. Torresi J: for the GeoSentinel Surveillance Network. (2007) Animal-associated injuries and related diseases among returned travellers: A review of the GeoSentinel Surveillance Network. Vaccine 25:2656-2663.

194. Elliott S, Payne PD, Duffy MF, Byrne TJ, Tham W-H, Rogerson SJ, BROWN GV, Eisen DP. (2007) Antibody recognition of heterologous variant surface antigens after a single Plasmodium falciparum infection in previously naive adults. Am J Trop Med Hyg 76:860-864.

195. Skull SA, Andrews RM, Byrnes GB, Kelly HA, Nolan TM, BROWN GV, Campbell DA. (2007) Prevention of community-acquired pneumonia among a cohort of hospitalized elderly: benefit due to influenza and pneumococcal vaccination not demonstrated. Vaccine 25: 4631-4640.

196. Worth L, Slavin M, BROWN GV, Black J. (2007) Catheter-related bloodstream infections in hematology: time for standardized surveillance? Cancer 109:1215-1226.

197. Tham WH, Payne PD, BROWN GV, Rogerson SJ. (2007) Identification of basic transcriptional elements required for rif gene transcription. Int J Parasitol 37:605-615.

27198. Skull SA, Andrews RM, Byrnes GB, Kelly HA, Nolan TM, BROWN GV, Campbell

DA. (2007) Missed opportunities to vaccinate a cohort of hospitalised elderly with pneumococcal and influenza vaccines. Vaccine 25:5146-5154.

199. Elliott SR, Spurck TP, Dodin JM, Maier AG, Voss TS, Yosaatmadja F, Payne PD, McFadden GI, Cowman AF, Rogerson SJ, Schofield L, BROWN GV. (2007). Inhibition of dendritic cell maturation by malaria is dose-dependent and does not require Plasmodium falciparum erythrocyte membrane protein 1. Infect Immun 75: 3621-3632.

200. Skull SA, Andrews RM, Byrnes GB, Kelly HA, Nolan TM, BROWN GV, Campbell DA. (2007) Validity of self-reported influenza and pneumococcal vaccination status among a cohort of hospitalized elderly inpatients. Vaccine 25: 4775-4783.

201. Beeson JG, Ndungu F, Persson KE, Chesson JM, Kelly GL, Uyoga S, Hallamore SL, Williams TN, Reeder JC, BROWN GV, Marsh K. (2007). Antibodies among men and children to placental-binding Plasmodium falciparum-infected erythrocytes that express var2csa. Am J Trop Med Hyg 77:22-28.

202. Hutchinson AF, Ghimire AK, Thompson MA, Black JF, Brand CA, Lowe AJ, Smallwood DM, Vlahos R, Bozinovski S, BROWN GV, Anderson GP, Irving LB. (2007). A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD. Respir Med 101:2472-2481.

203. Buising KL, Thursky KA, Black JP, Macgregor L, Street AC, Kennedy MP, BROWN GV. (2007) Identifying severe community-acquired pneumonia in the emergency department: A simple clinical prediction tool. Emerg Med Australas 19:418-426.

204. Skull SA, Andrews RM, Byrnes GB, Campbell DA, Nolan TM, BROWN GV, Kelly HA. (2008) ICD-10 codes are a valid tool for identification of pneumonia in hospitalized patients aged > of =65 years. Epidemiol Infect 136:232-240.

205. Buising KL, Thursky KA, Robertson MB, Black JF, Street AC, Richards MJ, BROWN GV. (2008) Electronic antibiotic stewardship – reduced consumption of broad spectrum antibiotics using a computerized antimicrobial approval system in a hospital setting. J Antimicrob Chemother 62:608-16.

206. Davis XM, MacDonald S, Borwein S, Freedman DO, Lozarsky PE, von Sonnenburg F, Keystone JS, Lim PL, Marano N, GeoSentinel Surveillance Network. Anglim A, Ansdell V, Brown G, Torresi J, Burchard GD, Chen LH, Connor BA, Delmont J, Parola P, Simon F, Field V, Gurtman A, Hale DC, Gelman SS, Jong EC, Haulman NJ, Roesel D, Kanagawa S, Kain KC, Franco-Paredes C, Libman MD, MacLean JD, Wilder-Smith A, Loutan L, Chappuis F, Lynch MW, McCarthy A, McLellan S, Nutman TB, Klion AD, Pandey P, Piyaphanee W, Silachamroon U, Sack RB, McKenzie R, Sagara H, Schwartz E, Shaw M, Stauffer WM, Walker PF, Steffen R, Schlagenhauf P, Weber R, Wilson ME. (2008) Health risks in travelers to China: the GeoSentinel experience and implications for the 2008 Beijing Olympics. Am J Trop Med Hyg 79:4-8.

207.Buising KL, Thursky KA, Black JF, Macgregor L, Street AC, Kennedy MP, BROWN GV. (2008). Empiric antibiotic prescribing for patients with community-acquired pneumonia: where can we improve? Intern Med J 38:174-7

208. Buising KL, Thursky KA, Black JF, MacGregor L, Street AC, Kennedy MP, BROWN GV. (2008) Improving antibiotic prescribing for adults with community acquired pneumonia: does a computerised decision support system achieve more than academic detailing alone? – a time series analysis. BMC Med Inform Mak 8: 35.

209.Yosaatmadja F, Andrews KT, Duffy MF, BROWN GV, Beeson JG, Rogerson SJ. (2008) Characterization of VAR2CSA-deficient

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28Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line. Malaria J 7:51

210.Noviyanti, R; Trianty, L; Duffy, M; Poespoprodjo, JR; Dadlani, H; Nursarnsy, N; Monintja, J; Kusuma, A; Trimarsanto, H; Lampah, D; Kenangalem, E; Tjitra, E; Price, R; Brown, G; Anstey, N; Rogerson, S. (2008) Malaria in pregnancy in Indonesia: Characterisation of Var2CSA transcripts, antibody response to Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1), and placental histology. American Journal of Tropical Medicine and Hygiene; 79; 6; p275-p275

211. Skull SA, Andrews RM, Byrnes GB, Campbell DA. Kelly HA, BROWN GV, Nolan TM. (2009) Hospitalised community-acquired pneumonia in the elderly: an Australian case-cohort study. Epidemiol Infect 137:194-202.

212. BROWN GV. (2009). Diagnosing the future. The Diplomat 8:44-45.213. BROWN GV. (2009). Ashdown Oration: Evidence based practice for travel and

tropical medicine. Ann Australasian Coll Trop Med 10:8-10214. Duffy MF, Byrne TJ, Carret C, Ivens A, BROWN GV. (2009) Ectopic recombination

of a malaria var gene during mitosis associated with an altered var switch rate. J Mol Biol 389:453-469.

215. BROWN GV, Sorrell TC. (2009) Building quality in health – the need for clinical researchers. Med J Aust 190:627-629.

216. Mueller I, Moorthy VS, BROWN GV, Smith PG, Alonso P, Genton B. on behalf of the WHO Malaria Vaccine Advisory Committee (MALVAC). (2009). Guidance on the evaluation of Plasmodium vivax vaccines in populations exposed to natural infection. Vaccine 27:5633-5643.

217. BROWN GV, Moorthy VS, Reed Z, Mendis K, Arevalo-Herrera M. Alonso P. (2009). Priorities in research and development of vaccines against Plasmodium vivax malaria. Vaccine 27:7228-7235.

218. BROWN GV. (2009). Science and technology in prevention and early detection of infectious diseases. In: Proceedings of the Theo Murphy High Flyers Think Tank. Australian Academy of Science. pp.79-91

219. Brown GV. (2009). Global health and the RACP. RACP News 29:8-9.220. Chen LH, Wilson ME, Davis X, Loutan L, Schwartz E, Keystone, Hale D, Lim PL,

McCarthy A, Gkrania-Klotsas E, Schlagenhauf P, for the GeoSentinel Surveillance Network (BROWN GV member of the Network). (2009). Illness in long-term travelers visiting GeoSentinel Clinics. Emerg Infect Dis 15:1773-1782.

221. Gautret P, Schlagenhauf P, Gaudart J, Castelli F, Brouqui P, von Sonnenburg F, Loutan L, Parola P, for the GeoSentinel Surveillance Network (BROWN GV member of the Network). (2009) Multicenter EuroTravNet/GeoSentinel study of travel-related infectious diseases in Europe. Emerg Infect Dis 15:1783-1790

222. Jensenius M, Davis X, von Sonnenburg F, Schwartz E, Keystone JS, Leder K, Lopez-Velez L, Caumes E, Cramer JP, Chen L, Parola P for the GeoSentinel Surveillance Network (BROWN GV member of the Network). (2009) Multicenter GeoSentinel analysis of rickettsial diseases in international travelers, 1996-2008. Emerg Infect Dis 15:1791-1798

223. Pinder M, Moorthy VS, Akanmori BD, Genton B, BROWN GV. (2010). MALVAC 2009: Progress and challenges in development of whole organism malaria vaccines for endemic countries, 3-4 June 2009, Dakar, Senegal. Vaccine 28:4695-4702.

224. BROWN GV, Rogerson SJ, McCormack J. (2010) Infectious diseases: a global perspective. In: Infectious Diseases: A clinical approach (third edition). (Eds. Yung A, Spelman D, Street Al, McCormack J. Sorrell T, Johnson P). pp.53-58.

29225. BROWN GV, Price R, Anstey N. (2010) Malaria. In: Infectious Diseases: A clinical

approach (third edition). (Eds. Yung A, Spelman D, Street A, McCormack J. Sorrell T, Johnson P). pp 350-365.

226. Alonso PL, BROWN G, Arevalo-Herrera M, Binka F, Chitnis C, Collins F, Doumbo OK, Greenwood B, Fenton Hall B. Levine MM, Mendis K, Newman RD, Plowe CV, Rodriguez MH, Sinden R, Slutsker L, Tanner M. (2011) A research agenda to underpin malaria eradication. PLoS Med 8(1): e1000406, doi: 10.1371

227. The malERA Consultative Group on Integration Strategies (2011) A research agenda for malaria eradication: Cross-cutting issues for eradication. PLos Med 8(1): e1000404 doi:10.1371 (BROWN GV a member of the writing group).

228. Petter M, Lee CC, Byrne TJ, Boysen KE, Volz J, Ralph SA, Cowman AF, BROWN GV, Duffy MF. (2011). Expression of P.falciparum var genes involves exchange of the histone variant H2A.Z at the promoter. PLoS Pathog 7(2) e1001292. (IF 8.978)

229. BROWN GV. (2011). Control and eradication of malaria: past, present and future. In: Health. (Ed Sykes H). Future Leaders. pp.35-83.

230. Menendez C, Moorthy VS, Reed Z, Bardaji A, Alonso P, BROWN GV. (2011) Development of vaccines to prevent malaria in pregnant women: WHO MALVAC meeting report. Expert Review of Vaccines. 2011 Sep;10(9):1271-80

231. Schwartz L, BROWN GV, Genton B, Moorthy VS. (2012) A review of malaria vaccine clinical projects based on the WHO rainbow table. Malaria Journal 2012 Jan 9;11(1):11

232. The malERA Consultative Group on Vaccines (2011) A research agenda for malaria eradication: vaccines. PLoS Med. 2011 Jan 25;8(1):e1000397. Review. (BROWN GV a member of the writing group)

233. Pinder M, Moorthy VS, Mendis K, Brown GV, MALVAC committee. MALVAC (2011) Measures of Efficacy of Anti-malarial Interventions against Malaria Transmission(http://www.who.int/vaccine_research/MALVAC_2010_meeting_report.pdf). 2010

234. Vannice, KS, Brown, GV, Akanmori, BD, Moorthy, VS. Malaria Journal (2012) MALVAC 2012 scientific forum: accelerating development of second-generation malaria vaccines Nov 09 11-20 Malaria Journal 2012, 11:372 doi:10.1186/1475-2875-11-372

235. Chua CL; Brown G; Hamilton JA; Rogerson S; Boeuf P, (2013) Monocytes and macrophages in malaria: protection or pathology? Trends In Parasitology Vol. 29 (1), pp. 26-34

236. Denholm JT, Leslie DE, Jenkin GA, Darby J, Johnson PD, Graham SM, Brown, GV, Sievers A, Globan M, Brown LK, McBryde ES, (2012) Long-term follow-up of contacts exposed to multidrug-resistant tuberculosis in Victoria, Australia, 1995-2010 Int J Tuberc Lung Dis Vol. 16 (10), pp. 1320-5

237. Denholm, Justin T., McBryde, Emma S., Brown, Graham V. (2012) Ethical evaluation of immigration screening policy for latent tuberculosis infection. Australian & New Zealand Journal of Public Health. Aug2012, Vol. 36 Issue 4, p325-328

238. Boeuf, P; Aitken, E; Chandrasiri, U; Chua, C; McInerney, B; McQuade, L; Duffy, M; Molyneux, M; Brown, G; Glazier, J; Rogerson, S. (2012) Plasmodium falciparum malaria elicits inflammatory responses that impair placental amino acid transport. PLoS Pathog 9 ;7(2) e1001292.

239. Chua CL, BROWN GV, Hamilton JA, Molyneux ME, Rogerson SJ, Boeuf P. (2013) Soluble CD163, a Product of Monocyte/Macrophage Activation, Is Inversely Associated with Haemoglobin Levels in Placental Malaria. PLoS One. 2013 May 22;8(5):e64127. doi: 10.1371/journal.pone.0064127. Print 2013.

30240. Leder K, Torresi J, Libman MD, Cramer JP, Castelli F, Schlagenhauf P, Wilder-

Smith A, Wilson ME, Keystone JS, Schwartz E, Barnett ED, von Sonnenburg F, Brownstein JS, Cheng AC, Sotir MJ, Esposito DH, Freedman DO; GeoSentinel Surveillance Network. (BROWN GV member of the Network) (2013) GeoSentinel surveillance of illness in returned travelers, 2007-2011. Ann Intern Med. 2013 Mar 19;158(6):456-68

241. Petter M, Selvarajah SA, Lee CC, Chin WH, Gupta AP, Bozdech Z, BROWN GV, Duffy MF. (2013) H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum. Mol Microbiol. 2013 Mar;87(6):1167-82

242, Singh, Megha, BROWN GRAHAM, Rogerson, Stephen J. (2013) Ownership and use of insecticide-treated nets during pregnancy in sub-Saharan Africa: a review. Malaria Journal. 2013, Vol. 12 Issue 1, p1-10.

243. Geoffrey AT Targett, Vasee S Moorthy, and Graham V Brown (2013) Malaria vaccine research and development: the role of the WHO MALVAC committee. Malaria Journal 2013, 12:362 doi:10.1186/1475-2875-12-362

245 Teo A1, Hasang W, Randall LM, Feng G, Bell L, Unger H, Langer C, Beeson JG, Siba PM, Mueller I, Molyneux ME, Brown GV, Rogerson SJ. (2014) Decreasing malaria prevalence and its potential consequences for immunity in pregnant women. J Infect Dis. 2014 1444-55

246 Chua CL, Robinson LJ, Baiwog F, Stanisic DI, Hamilton JA, Brown GV, Rogerson SJ, Boeuf P. (2014) High numbers of circulating pigmented polymorphonuclear neutrophils as a prognostic marker for decreased birth weight during malaria in pregnancy. Int J Parasitol. 2015 Feb;45(2-3):107-11 doi:10.1016/j.ijpara. 2014.12.002. Epub 2014 Dec 31.

247 Teo A, Hasang W, Randall L.M, Unger H, Siba PM, Mueller I, Brown GV and Rogerson SJ. Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission Malaria Journal 2015, 14:215-222

248 Josling, G. A., Petter, M., Oehring, S. C., Gupta, A. P., Dietz, O., Wilson, D. W., Schubert, T., Langst, G., Gilson, P. R., Crabb, B. S., Moes, S., Jenoe, P., Lim, S. W., Brown, G. V., Bozdech, Z., Voss, T. S. & Duffy, M. F. 2015. A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression. Cell Host Microbe, 17, 741-51

249 Graham Brown and Stephen Rogerson, 2016 Malaria: Global challenges for malaria eradication (Microbiology Australia, In press)

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