BRENDA Tutorial

BRENDA Tissue OntologyBTO

The BTO is a comprehensive

structuredencyclopedia…

…to connect enzymedata with the Source Tissue information in

BRENDA.

On the BTO page you find a form to search for a specificterm, including text miningresults…

…or you can restrict your searchto manually annotated BRENDA information.

In the Tree View you canbrowse along the different

classification categories(animal, fungi, plant etc..

Click on the (+) icon to expandand on the (-) icon to collapsea Tree View branch.

You can get the definition ofthe Source Tissue via a mouseover across the term.

The abbreviations areexplained in the legend

In the box you find more details…

BTO-ID

definition

references

…and the number of all EC numbers listed in a dropdown menu directly linkedto the BRENDA Enzyme Summary Pages.

To search for more details on the enzyme source you can

perform a query by clicking on

You can either searchfor the exact term…

...or search for the termincluding all descendants

On the result page all enzymesconnected to the enzymesource of interest are listed.

By clicking on the EC number the Enzyme Summary Page will be opened…

…to find all dataincluding furtherenzyme sources.

If you are interested in other enzyme sources, click on the term…

…and you will be back on theBTO web page…

…to receive more detailedinformation.