Breast Cancer Surveillance Consortium (BCSC):

Impact of the BCSCWhat is left to be done

Stephen Taplin, MD, MPH, Senior Scientist NCI/DCCPS/ARPBCSC Program Director

PI of BCSC site (GHC) 1994-2003

First Some Thanks

To the people who put this meeting together

Kathy Sedgwick

Emily Dowling

Katherine McElroy

Impressive Productivity

BCSC Publications

0

5

10

15

20

25

30

35

1994 1996 1998 2000 2002 2004 2006 2008

Year

Nu

mb

er o

f P

ub

licat

ion

s

Publications

Linear (Publications)

Publications from Pooled Data

• Total publications

• 150 in 2004 - 374 in 2010 & climbing

• Pooled publications

In Important areas & Journals

Research Productivity as well

• Research

• A major focus of the last 5 years with major results

• 65 grants

And Training/mentoring

• Multidisciplinary exchange/discussion

• Junior investigators

• 5+ careers developed

• 3 career development awards

• 36 publications since 2005

Accomplishments

Contributions to science – a small proportion today

Methods –

• Performance measures

• Longitudinal pooled, secure data with meta-data definitions

Risk models

• Density and breast cancer risk

Evidence

• Cisnet, the USPSTF, the American College of Radiology

Variation in interpretive performance

• Wide variation among individuals and facilities

Accomplishments

Interventions

Measurement

• Automated feedback

Testing

• Live vs. test sets

• Blazing a trail for technologic advances

• Acrin

Impact on Clinical Care

BI-RADS

Influenced the lexicon

Interaction with ACR

MQSA

IOM report

• AIM

Clinicians

119 involved in testing

Beyond the science there was also productivity and a life

•Marriages•Newborns•Camaraderie•Retirements

Future work

International comparisons

Test sets

Comparative effectiveness

Technology (MRI, Digital vs. Screen film)

Protocols (1 vs. 2 years)

Measurement

Performance

Feedback

Future funding

Po1-

Risk-based screening

Shared resource

Leverage the experience with sharing data

Support the teams through December

Conclusion – We are turning the page

We’ve had a productive set of chapters

Thanks to the investigators

Thanks to the many programmers, data management people, and all of the team who made the BCSC possible

Let’s go celebrate

Reception at 6 in Room Concours Terrace

Dinner at 7 – Haverford Ballroom