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Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate Department of Clinical Epidemiology and Biostatistics McMaster University

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Page 1: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Book Review:

Generalized Linear and Nonlinear

Models for Correlated Data

Author: Edward F. Vonesh

Reviewed by:

Divya Joshi, PhD Candidate

Department of Clinical Epidemiology and

Biostatistics

McMaster University

Page 2: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Topics covered in this book…

1. Linear models (LM)

2. Linear mixed-effects models (LME)

3. Generalized linear models (GLIM)

4. Generalized linear mixed-effects models (GLME)

5. Nonlinear models (NLM)

6. Nonlinear mixed-effects models (NLME)

7. Generalized nonlinear models (NGLM)

8. Generalized nonlinear mixed-effects models (GNLME)

Page 3: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Assumption of Independence

Page 4: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Book Summary

This book discusses the theory and analysis of

continuous or discrete correlated data in

longitudinal or clustered studies using SAS

Special emphasis is placed on applications that

require the use of generalized linear and non-

linear models

Page 5: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Author: Edward F. Vonesh, PhD

Professor of Preventive Medicine at Northwestern

University

Senior research scientist at Baxter Healthcare

Owner of Vonesh Statistical Consulting, LLC.

SAS user since 1974

Page 6: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Strengths of the Book

Other topics covered in the book include:

Missing data in longitudinal clinical trials

Pharmacokinetic applications

Joint modeling of longitudinal data and survival data

Page 7: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Strengths

Well written, concise

Real-world applications

Applicable to a large audience

All SAS codes are provided

Datasets available online

Page 8: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Weakness

Emphasis on theory and equations

Page 9: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Recommend?

Statisticians

Researchers conducting longitudinal or

clustered studies in various fields

Students who are just beginning to work with

longitudinal or clustered data

Page 10: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Learning & Tips

I learned how to use SAS for joint

modeling of longitudinal and survival

data

How to effectively deal with missing

data in longitudinal studies

Page 11: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Application

Page 12: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Other Books

Wu, L. (2010). Mixed Effects Models for Complex Data.

Littell, R.C., Milliken, G.A., Stroup, W.W., Wolfinger,

R.D., & Schabenberger, O. (2006). SAS for Mixed

Models (2nd ed.).

Page 13: Book Review - SAS Group Presentati… · Book Review: Generalized Linear and Nonlinear Models for Correlated Data Author: Edward F. Vonesh Reviewed by: Divya Joshi, PhD Candidate

Questions?