biotech santé | e.c. and n.i.h. projects : double your funding opportunities by claire skentelbery...

Les points sur les i

Dr Claire SKENTELBERY – Secretary General, European Biotechnology Foundation Prof. J. BALTHAZART and Dr Julie BAKKER, ULg-GIGA Neurosciences Isabelle RAUSIN, ULg-Interface and Jérôme EECKHOUT, ULg-ARD

Health researchers : double your funding opportunities and those of your U.S. partners, by targeting jointly E.C. and N.I.H. projects

Avec le soutien de :

15.2.2012 www.european-biotechnology.net 1

Building transatlantic research partnerships Claire Skentelbery European Biotechnology Network

Mission for today

•  Introduce European Biotechnology Network •  Understand tools available to build US

research partnerships •  Suitability for your work •  Plan 2012 opportunities •  Get to work!


Getting introduced

•  Cross sectoral network in biotech •  Mission to facilitate partnership •  Delivering biotechnology – critical mass,

accelerated pace •  Biotechnology Funding Hub •  Strong focus on SME/industry inclusion •  Global focus for Europe


Liege as a Network member •  For researchers and support staff •  Sign up to the Network each and every one! •  Free subscription to European Biotechnology

News – sign up to get your personal copy •  Funding Hub news – get the latest updates •  Free access to Network events/training •  Priority speaker places at events •  Direct assistance in project development •  Hub around which we can build projects


Offer today •  Doing the business in the US!

–  March 29th, Brussels –  Small intensive workshop –  Logistics of building a successful US partnership –  €100 Corporate members

•  Building Transatlantic partnerships –  March 30th, Brussels –  NIH, EC, DoD, Gates Foundation –  Broader look at funding and experiences –  2 free places for Corporate members


Biotechnology Funding Hub

•  Track funding open to SMEs in Europe; EC, Eurostars, eurotransbio, NIH, DoD

•  Mission to build collaborative partnerships •  Work with members to find projects and

develop proposals •  Training/advice/signposting •  Skype/phone surgeries


Opportunities

•  National Institutes of Health

•  Department of Defense

•  Last call in FP7


DoD 2012 – in a nutshell •  Secret funding tool – wide funding range •  Projects, fellowships – open to global application •  Few active in Europe, almost all in UK •  Significant opportunities for partnered applications:

–  Across all biology –  Diagnostics, vaccines, disease management, real

time & remote technologies –  Projects in Europe include breast cancer,

immunotherapy, lung cancer etc. 8 topics currently open

www.grants.gov 15.2.2012 www.european-biotechnology.net 8

FP7 2012 – in a nutshell

– Last call in 2012 – Lots of support in Liege – Opportunity to engage US partners for EC

projects - € directly from Brussels – Strong SME partnership opportunity – EBN working with NIH to matchmake

research for FP7


NIH: Where to start? •  NIH enormous research and funding platform •  Aim of talk to address from practical perspective

–  What is it? –  Opportunities for me –  How to access projects –  Chances of success –  Best approach –  Finding partners –  Who can help me?


What is NIH? •  NIH’s mission is to seek fundamental knowledge about

the nature and behaviour of living systems and the application of that knowledge to enhance health, lengthen life, and reduce the burdens of illness and disability.

•  Broad programme – basic-applied/clinical research •  $31.2 billion annual budget – squeezed in 2011/12


Institutes of the NIH

•  27! •  Cancer, eye, Heart lung and blood, human genome,

ageing, alcohol abuse, allergy & infectious disease, arthritis & skin disease, imaging and bioengineering, child health, deafness & communication disorders, dental & craniofacial, diabetes, digestive & kidney diseases, drug abuse, env health, general medical sciences, mental health, neurological disorders & stroke, nursing, rare/neglected diseases

•  New - National Center for Advancing Translational Sciences’


Each Institute has…

•  Own mission and structure •  Own research funding programme and budget •  Dedicated funding or joint funding with other

Institutes •  Budget varies hugely


Opportunities open for me?

•  Focus on main funding programmes suitable •  Programmes launched – open 4 years •  3 deadlines/year – multiple application

opportunities •  Main programmes open to non-US application For non-US success, must either:

– Be not available in US – Significant benefit to US research


Programme announcements (PA) •  General areas of high priority •  Proposals submitted at any time of year •  Evaluated 3 times/year •  Evaluation timescale:

– Scientific merit review: 2-3 months – Advisory Council: 4-5 months – Earliest start: 6-7 months

720 PAs open NOW!


Requests for Application (RFA)

•  More specific research applications •  Often single deadline

92 RFAs open now!


Project types - R21

– Exploratory, groundbreaking research – Max 2 years – Max $275,000 – Encouraged to contact NIH during

development stage


Project types – R01 –  ‘Original’ proposal type –  PI nominates topic and focus within programme

announcement –  Covers salary, equipment, consultants, contract

services, indirect costs, travel –  No max cost BUT:

•  €25,000 modules up to module limit of $250k •  Max 5 periods – usually 12 months each •  All non-US applicants must have detailed budget

–  1 resubmission allowed –  Encouraged to contact NIH


Project types - P01

•  Research program projects •  Broad based •  Multidisciplinary •  Long term •  All address different elements of common

objectives •  Industry encouraged – non-US also •  No budget max unless stated


Funding level/success rates? Varies between Institute: 2010 examples •  NCI: 17% - $516 million •  NIAID (allergy/infectious disease): 24% - $506 million •  NHLBI (heart/lung/blood): 20% - $416 million •  NIGMS (general): 27% - $336 million •  NIDDK (diabetes/digestive/kidney): 26% - $333 million This counts project renewal: higher % for those New project: More like 10% success


Proposal contents

•  Pleasingly similar between all! •  Get familiar with PHS398 – core example


Proposal core elements – Budget for initial/whole – Research plan:

• Aims • Strategy – see next slide •  Inclusion – women/minorities • Enrolment • Agent research • Leadership plan • Consortium/contractual plan


Research strategy contents

•  Significance (problem, scientific advance, impact)

•  Innovation (changes to current practice, novelty and advantage)

•  Approach (strategy, method, analyses, data collection, risk management, hazards)

•  Preliminary studies for new applications No max length: detailed, clear and concise!


Example Programme announcement


PA cont


Quick summary

•  Each call VERY detailed •  Expectations listed •  Eligibility defined •  Direct contact details for each •  Deadlines •  All hyperlinked


Information overload?

•  Looked at: –  Institutes – Funding programmes – Project types – Success rates

•  What now?


If I was doing this…….

•  First time European applicant? •  Find suitable call topic •  Find European organisations already playing in

US – several in the room! •  Find US partners you KNOW and are active in

NIH •  Understand history of funding in this area •  Try and join/develop US-led proposal •  Go prepared to a key US conf and partner


Resources to use

•  Searchable database on NIH website http://projectreporter.nih.gov/reporter.cfm •  Many funding reports available •  Find groups active in your field – great starting

point



Thank you"

Good hunting!"

biotech santé | e.c. and n.i.h. projects : double your funding opportunities by claire skentelbery...

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