Biostamina Kft is a manufacturer of 100% natural phytotherapeutic medical devices, made up exclusively of medicinal plant extracts and distributes its products in Europe and the rest of the world.

Born from an idea of its founder Dr. R. Soldati which for years has been dedicated to the creation of safe and natural products enriched with stem cells and ozone O3.

“Our mission is to offer our experience at the service of the latest technologies of medical devices and the medical and cosmetic industries”

BIOSTAMINA KFTOWNER OF PHYTOTHERAPIC PATENTS FOR TISSUE AND BONE REGENERATION

* In vitro scientific tests conducted on Bio Regenera® Dental certifies that the product, with its barrier effect, determines a significant increase in cell viability within 48/72

hours, therefore, regenerating activities of osteoblasts and keratinocytes.

Lipogel Bio-Regeneratingand Bio-Healing

The first 100% natural Lipogel, enriched with ozone, relieves pain,

promotes healing and tissue regeneration

BIOSTAMINA KFT1143 Budapest, Stefánia út 81. 2/9 Email: marketing@biostamina.org

Tel HU. +36 702180902 • Tel IT. +39 3515265919

www.biorigeneradental.com

PRODUCT TESTED BY “ANTROPOS SA” SCIENTIFIC AND UNIVERSITY RESEARCH INSTITUTE

SWISS. CH 6900 LUGANO

ROME - DUBAIBUDAPEST - LONDON

Biorigeneradental

Rev.

21/0

3/19

* Bio Basic Europe S.r.l.

cl. IIb

Its formulation, rich in essential oils, accelerates the tissue re-pair process. Thanks to its particular consistency, Bio RIGENERA® Dental O3 forms a protective film on the lesion, favoring a rapid and correct reepithalisation of the gums and mucosa of the oral cavity and helping to alleviate pain. The ozonation of the essential oils of the medicinal plants contained in Bio RIGENERA® Dental O3, gives the product a high power curative for lesions of the oral cavity.

PHYTOTHERAPY: Plant oils can stimulate the cells present in our body, and while they are not losing their regenerating and repai-ring potential, with the passing of time they slow down in their function of renewal. The properties of essential oils consist in re-ducing the formation of MMP1, enzymes responsible for the de-gradation of collagen and for the inflammation of the oral cavitly and mucose.

Bio RIGENERA® Dental O3 is indicated as an adjunct in the treatment and insituations of:• Small lesions due to surgical dental interventions • Perimplantitis surgery • Ideal to prevent, or lessen post-operative pain • Gingivitis, parodontitis, periimplantitis • Together with the use of pro-sthetic and orthodontic appliances • After scaling and oral hygiene interventions • After extraction Simple or complex • In case of minor burns • In Lip Herpes Therapy and Afte • Ideal in oral infec-tions • Ideal in the pathologies of the oral mucosa • Also indicated for diabetic patients.

INGREDIENTS:Anhydrous and concentrated natural phytotherapy product made up of 100% of medicinal herb extracts derived from con-trolled crops of Mediterranean origin, with the addition of O3 ozone

DIRECTIONS FOR USE: Apply to the injured party to be treated. Use your fingers or a soft toothbrush and massage for one minute, two or three times a day. After clea-ning, wearers of removable dentures should apply a small amount of gingival lipogel to the surfaces that come into contact with the gums. It is recommended that you do not eat food for at least thirty minutes after use.

WARNINGS: Do not use in case of confirmed or suspected hypersensitivity or allergy to one or more components. Pediatric use is not recommended. Avoid contact with eyes; in case of contact rinse it with fresh water. If you experience allergies or other adverse effects, discontinue to use it and consult your doctor. Keep out of reach of children. The expiry date refers to the product intact and properly stored in a dry place. It is recommended to use the product within 12 months from opening. No reported side effects. For the simultaneous use of topical me-dication treatments consult your doctor.

Lipogel Bio-Regeneratingand Bio-Healing

The presence of the plaque determines a gingivitis which is a clinical picture present in almost all individuals in which it is not possible to highlight a reabsorption of the alveolar bone. In many cases we are faced with subjects with paradontitis, a disease that affected the 20-30% of the adult population where in addition to the alveolar bone tissue, there was a loss of paradontal fibers and a recurrence of the attachment of the gingiva epithelium resulting in further deepening of the gingival groove. All this can lead to an instability in the dental element and tooth loss.

The properties of grapefruit seeds and ozone, have anti-bacterial effect and contribute to quick and correct gin-gival regeneration and of the oral mucosa. The use of Bio RIGENERA® Dental O3 in dentistry for the treatment of oral mucosal diseases is explained by the inherent proper-ties of these molecules, namely in their Antioxidant, anti-edema, antibacterial and re-epitelizing actions.. Thanks to its pleasing odor and taste, it makes the painful sym-ptomatology and bleeding to contact faster, with a quick regeneration of the sore skin.

a.Patient age 48 with serious illness recession of the lower central incisors

(photo preoperative)

Patient two months after surgery treated curettage and ablation,treated twice daily with product Biorigenera dental