bioregulatorymedicine anewmedicalparadigm 140326194133 phpapp01 2
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integrated system biology medicine
©
Principles of the Bioregulatory Medicine
BIOREGULATORY ME I!I"E
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title
British Academy for Bioregulatory Medicine
®
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title
Dr Damir A Shakambet M.D.
Biomedic Centre
23 Manchester Street
London W1U 4DJ
tel 44 ! 2"# $3% &'&&
(((.biomedic.co.)kin*)ir+,biomedic.co.)k
®
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Introduction to
Bioregulatory Medicine
- re/alence o0 De enerati/e
and Mali nant Diseases
- Allo athic treatment based onbiochemical or mechanistica roach
- oor s)ccess 0or com lediseases
- eed 0or ne( treatment
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Introduction to
Bioregulatory Medicine
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Introduction to
Bioregulatory Medicine
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What are solutions?
ersonalisedre/entati/e5 redicti/e
S+stem Biolo + 6 M)lti0actorial 6 Balancin 6 Sel0 healin otential
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Dynamic HealthModel
Presomatic Acute
Chronic
S T A T I C MOD !
Degenerati"e
D # $ A M I C MOD !
on!s) ressi/e Biore )lator+ re/ersal
S) ressi/e disease sta e treatment
Malignant
Introduction to
Bioregulatory Medicine
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Scientifc Paradigm Shi t
%& m'iricism (Aristotle)and !inear 'aradigm ofcause*effect (Descartes)
+& Singular Aetiologicalfactor determinesTreatment
,& Palliati"e treatment
-& Increased incidence ofchronic and malignant
diseases
%& System Biology * multifactorialcauses Integrati"e and .olistictreatment
+& Multi*causal treatment ofsu''orting .omeostasis
,& Causati"e and Pre"entati"etreatment
-& Decreased incidence ofchronic and malignant
diseases
Current MedicalModel
New Medical Model ©
Introduction to
Bioregulatory Medicine
I d i
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Dynamic Model oHealth
Disease orientated model
Waitin 0or s+m toms
Dia nosis!0i ed7 criteriabased
rolon li0e and alliati/etreatment
Health orientated model
Early presomatic signs
Diagnosis-fexible andpersonalised search ordysregulation
Reversal o Chronicdisease and causaltreatment
Old Static model $e/ Dynamic model
Introduction to
Bioregulatory Medicine
S Bi l d Bi
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System Biology and Bioin ormatics
Biolo ical Com le S+stems
"Systems biology is putting together rather than taking apart,favouring integration rather than reduction. It means changing
our philosophy, in the full sense of the term"
Denis oble
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8 9:;MA
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Bertalanffy Prigogine
- Biolo ical o en s+stems
- ?ro) o0 ob@ects that (ork inconcert rod)ce some res)lt
- S+stem as a set o0 inde endentand interactin arts.
0eneral System Theory
Self*organisation
Ilya Prigogine
1$1#!2""3
- M)lti le interactions o0 the s+stem- :r anisation is s ontaneo)s as
attem t to o to e*)ilibri)m as a 0ormo0 resonance.- Balance o0 e loitation and
e loration
Karl Ludwig von ertalanffy
1$"1!1$#2
Biolo ical Com le S+stems
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Wiener
!ystems "iologyBiolo ical Com le S+stems
Ti d di i#rinciples o "ioregulation
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Time and space medicine#rinciples o ioregulationand Homeostasis
1 e r t i c a
l
.ori2ontal
Disease le+els#rinciples o "ioregulation
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D % ! E & ! E
H E & ' ( H
Emotional Bioenergetic
Biochemical
Humoral
!ntercellular "Matri#$
Cellular
B ! % & % ' ! C ( & D ! ) ! S ! % N
*
E ' * E S
S! ) E
P
*
%
'
*
E
S
S
! )
E
Disease le+els,space medicine-
#rinciples o ioregulation
and Homeostasis
Ch l Di#rinciples o "ioregulation
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Chronology o Disease,time medicine-
c p es o o egu at o
and Homeostasis
hori2ontal a3is*time
Homeostatic ailure#rinciples o "ioregulation
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Homeostatic ailure.Dis/ease0
p g
and Homeostasis
Bioelectroma netism and
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Bioin ormation=)man lectro h+siolo +
S tPsycho/neuro/immune
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Systeminterrelationship
Psycho/neuro/immuneSystems
'round regulating Systems
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D$A P$ I
Cell
rece'tors
Transducing
Signalling
'igenetic
regulating'roteins
$er"e Biological Connecti"e
Path/ays molecules fibres
Bioin ormatics and DN( / PNE! Control
P $
I
D$A
04S
EN)!*%NMENT
=omeothera e)ticals
#rinciples o "ioregulation
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n/ironment is +o)r e ternal metabolism
Dr )ax erson
E#ternal1internal en+ironmentsystem control
and Homeostasis
P $ I 04SInternal en"ironment
D$A
3ternal en"ironment
Biolo ical terrain
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Biological terrain and Clinical cology
and Clinical colo +
Biolo ical terrain
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%#idati+e stress
(issuelesion
Augmented en2ymesthat 'roduce radicals
Phagocytosis!n2ammation"(cti+ation o thephospholipases3cycloo#ygenases y
lypoo#ygenases$
Destruction o theantio#idants*elease o metalsand proteins"hemoglo4in3myoglo4in$ !nterruption oelectron transport
Trauma
.eat
Infection
To3ins
0eo'atic
and Clinical colo +
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;eh+dration;eh+drationdeh+drationdeh+dration
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pH*+,.
pH*+,/
8ncreased
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Bioregulatory
Deto#ifcation
Deto#ifcation
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Deto#ifcation
cellulardetoxification
matrix
detoxification
capillary ylymphatic
detoxification
-KIDNEYS
-LIVER G BLADDER
e n i r o n m e n
t
-!"#$SAS
-%&in e x c r e t
i o n
Biolo ical terrain
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Bioregulatory
Micro4iome treatment0'a bact1rie n2est rien, C2est le terrain 3ui ait tout0
' #asteur
and Clinical colo +
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StructuralBioregulatory treatment
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Psycho*"egetati"e treatment
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Summary
The End
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The End