BIOPTIK TECHNOLOGY, INC.

OUTLOOKDECEMBER 2019

LISTED NUMBER: 4161

1

AGENDA

Performance

Product and Forecast

Corporate Introduction

2

CORPORATE INTRODUCTION• Date of Establishment: June 1st, 1999• Entity: Incorporation• Listing• IPO: June, 2011• July, 2011 at emerging stock market • June, 2013 OTC-listed; list number: 4161• Product Category: Medical Device, Medical In Vitro

Diagnostic Device, Telehealth, Skin Care Products, Food Supplements, and Wound therapy products, Natural Astaxanthin 3

ORGANIZATION CHART

4

Bioptik Technology, Inc.

Biored Technology,

Inc.

Biowater Technology,

Inc.

Bioptik-Cayman Inc.

Guangdong Bioptik

Technology, Inc.

69.9% 100%

100%

100%

QUALITY SYSTEM• ISO 13485• GMP(Good Manufacturing Practice in Taiwan)• Product: CE IVD(European Union), FDA(USA), SFDA(China)

approved, Health dept of Taiwan passed.

• ISO 9001; ISO 22716；ISO22000；HACCP ；ISO13485

5

Hsinchu Science Park Branch Office

Headquarter

Tainan Office and subsidiary - BioredTechnology, Inc.

6

HEADQUARTER MEDICAL DEVICE AND MEDICAL IN VITRO DIAGNOSTIC DEVICE

7

G Blood Glucose Monitoring System

GU Blood Glucose/Uric Acid Dual-Function Monitoring

System

GC Blood Glucose/Cholesterol

Dual-Function Monitoring System

GCU Blood Glucose/Cholesterol /Uric Acid Monitoring System

ET-5661 EasyMate Plus Blood Glucose/Cholesterol/Uric Acid/Hemoglobin/Triglyceride Monitoring System

BPGC Blood Pressure /Glucose/Cholesterol

Multi-function Monitoring System

G Blood Glucose Monitoring System

GU Blood Glucose/Uric Acid Dual-Function Monitoring System

GC Blood Glucose/Cholesterol Dual-Function Monitoring System

GCU Blood Glucose/Cholesterol /Uric Acid Monitoring System

ET-5661 EasyMate Plus Blood Glucose/Cholesterol/Uric Acid/Hemoglobin/Triglyceride Monitoring System

BPGC Blood Pressure /Glucose/Cholesterol Multi-function Monitoring System

HIGHLIGHTS – IOT APPLICATIONS

8

Monitoring System Connects to Mobile

Device

Monitoring System Connects to Mobile

Device

Monitoring System Connects to Tablet

Monitoring System Connects to Tablet

Barcode Application Data Transmission POCT Health SystemData Management

DEVELOPING PROJECTS WITH EXTERNAL COMPANIES

9

Turn on the App

Home Glucose measurement

Bluetooth pairing

Measurement mode

Startmeasurement

Insert strip Apply sample Countdown Resurt

HEADQUARTER FORECAST• IoT• Long-term Care Platform• Preventive Diagnostics and Precision Medicines

10

Long-term Care System

Healthcare System

Social Work System

Professional Healthcare System

trans-disciplinary System

Vital Value System

Indicator Monitoring System

General Affairs System

Human Resource System

11

Automatically uploading to system

Measurement

Using Wireless Monitoring Device

Clinical Operation Flow

*Blood Pressure Meter*Oximeter*Ear Thermometer*Blood Glucose Meter*Thermometer*Stadiometer*Weight Scale

Information Platform

1.ID Enter Patient’s ID2.ID Enter Operator’s ID3.Reading device Obtains Information

Using Wireless Monitoring Device

Vital Information Measurement and Storage

12

Equipped with wireless transmission technology in compliance to safety standard recognized worldwide

Vital information collected for both medical divisions as well as homecare patients. Devices are:NIBP/HR/BT/SpO2/BG/UA/CHOL/Scales

Structure

13

Information Appliances

Customized Vital Signs Display

14

★Data output*TPR output directly*Accelerate staff

handovers

★★ Data format*Basic data maintenance

*Nursing Information・Vital Signs・ Condition

records

Mobile Home Healthcare and Care Platform

15

Smart Homecare SchedulingPlatform

Enhance the benefits of hospitals and encourage action-based home care

Improve preventive care and medical tracking Constructing integrated massive data to provide treatment

decision analysis Route Planning Location Guide Check-in Tag Professional Medical Platform Digital Signature Validation

Method Mobile Application for Healthcare Professionals Download APP Daily information recording

Long-term Care

16

HSINCHU SCIENCE PARK BRANCH SKIN CARE PRODUCTS, FOOD SUPPLEMENTS, AND WOUND THERAPY PRODUCTS

Far Yea Product Series

Pharmacy Channels

ACUREAL Product Series

Medical Grade Scar

Gel

YU JIAN Dietary

Supplement Series

17

Scar therapy gel

HSINCHU SCIENCE PARK BRANCHFOOD SUPPLEMENTS

18

DIETARY SUPPLEMENT –INFOMERCIAL –PSAC ASTAXANTHIN CAPSULE

19

Infomercial PSAC astaxanthin capsule -Newly developed food supplement astaxanthin product targeting three hypers.

DIETARY SUPPLEMENT –INFOMERCIAL –ACTION FREE

20

Action Free capsule –Based on 20 years of research experience, hyaluronic acid based dietary supplement developed for joint health can effectively improve joint discomfort

DIETARY SUPPLEMENT – PHYSICAL CHANNEL

21

Currently sold at Great Tree Pharmacy and Tin Tin Drugstore, and will expand to major channels in Taiwan in 2020

HSINCHU SCIENCE PARK BRANCH FORECAST

22

• Southeast Asia Market Expansion

• Virtual Channel Development

• Foreign OEM Market Development

Skin Care Products

• Infomercial Product Development

• Physical Channel Expansion

• Functional Product Development

Food Supplements • Scar Care

• Wound Care• Pharmacy Market

Expansion

Wound therapy products

HSINCHU SCIENCE PARK BRANCH OUTLOOK

2020 FUNCTIONAL PRODUCT DEVELOPMENT

23

Supplement for Cartilage and

Bone

Advanced Action Free

Product

Allergy and intestinal health

productsProbiotics

AcurealHyaluronic

Acid Essence

Hyaluronic Acid Skin

Care Product

Bioptik Technology Inc.---

Expert on Guarding Your Health

SUBSIDIARY BIORED NATURAL ASTAXANTHIN

24

Feed/ ester-state astaxanthin (2%)

Food grade/ free-state astaxanthin (2%)

Medical grade/ free-state astaxanthin (98%)As a mega antioxidant, it slows down the oxidation reaction to eliminates the chain reaction of free radicals, hence to protect cells against oxidation.Highly purified medical grade free-state astaxanthin can be used as supplement to traditional therapy.Marketing: medical supplement, laboratory reference material

Protect cells against oxidation with antioxidant propertyWith the benefits of antioxidant property to eliminate free radical, it can serve as dietary supplement with compound substances for additive effect, such as promoting eye health and immunity, preventing of atherosclerosis cardiovascular diseases.Marketing: Dietary supplement additives

Egg yolk coloring and add antioxidant benefit as additive valueColoring on aquatic livestock to elevate marketing valuePromote gonadal gland health and increase conception rateIncrease cell membrane elasticity and resistanceMarketing: aquaculture and livestock feed additive

Micronised Free Form AstaxanthinHomogenization Technology

25

Publications

26

• 1.Y.-Y. Chen, P.-C. Lee, Y.-L. Wu and L.-Y. Liu, In Vivo Effects of Free FormAstaxanthin Powder on Anti-Oxidation and Lipid Metabolism with High-Cholesterol Diet, PLoS One, 2015, 10(8), e0134733.

• 2.Wu, Y.J.; Wu, Y.C.; Chen, I.F.; Wu, Y.L.; Chuang, C.W.; Huang, H.H.; Kuo,S.M. Reparative Effects of Astaxanthin-Hyaluronan Nanoaggregates againstRetrorsine-CCl4-Induced Liver Fibrosis and Necrosis. Molecules 2018, 23, 726.

• 3.Wu, Y.C.; Huang, H.H.; Wu, Y.J.; Manousakas, I.; Yang, C.C.; Kuo, S.M.Therapeutic and Protective Effects of Liposomal Encapsulation of Astaxanthinin Mice with Alcoholic Liver Fibrosis. Int. J. Mol. Sci 2019, 20, 4057.

• 4.游離態蝦紅素處理方法 中華民國 發明專利申請案號:108108474. 案件申請日期:2019/03/13

• 5.蝦紅素粉固相均勻化之方法 中華民國 發明專利申請案號:108108475.案件申請日期:2019/03/13

IN VIVO EFFECTS OF ASTAXANTHIN• In Vivo Effects of Free Form Astaxanthin Powder on Anti-Oxidation and Lipid Metabolism

with High-Cholesterol Diet PLoS One, 2015, 10(8), e0134733.

27

Ethanol-induced severe liver fibrosis- alcohol-induced liver damage treat with Astaxanthin (I-Shou University/ Department of Biomedical Engineering)Therapeutic and Protective Effects of Liposomal Encapsulation of Astaxanthinin Mice with Alcoholic Liver Fibrosis. Int. J. Mol. Sci 2019, 20, 4057.

28

Normal mouse liver

Normal liver dissection

Alcohol-induced liver damage

Oral Astaxanthintreatment

Intraperitoneal injection Astaxanthin treatment

Damaged liver dissection – liver fibrosis

＊ Alcohol-induced liver damage animal model shows the effectiveness of astaxanthin treatment according to the liver dissection. Injection method is superior than oral dosage treatment according to the experiment conducted.

Liver dissection after oral treatment

Liver dissection afterinjection treatment

Reparative Effects of Astaxanthin-Hyaluronan Nanoaggregates against Retrorsine-CCl4-Induced Liver Fibrosis and Necrosis. Molecules 2018, 23, 726.

29

30

Abstraction/ purification

Mechanofusion

Microencapsulation

Class 3 registration progress

Efficacy Evaluation Human Daily Dosage: 6mg/60kg B.W. Material Product1. Cholesterol induced fatty liver treatment evaluation ○ -2. Ethanol liver damage treatment evaluation ○ -3. Astaxanthin-hyaluronan nanocapsules repair carbon tetrachloride-induced liver fibrosis and necrosis ○ -

4. Tetrachloride-induced severe liver fibrosis - Chemical liver damage treatment evaluation ◎ ●

Safety Evaluation Human Daily Dosage: 80mg/60kg B.W. Material Product1. Salmonella reverse mutation test ● ●2. Micronuclei in peripheral blood of rodents ● ●3. Chromosomal aberration test with mammalian cells in culture ● ●4. Teratogenicity ● ●90-day feeding toxicity study: 120MOS; 1600 times of the dosage ● ●

Astaxanthin Stability Evaluation PTP (10 piece/ tablet) Material Product6 month accelerated test/ 24 months long term test/40℃，75%RH ◎ ●

Product Performance Assessments

31

Scores of liver fibrosis induced in rats: None (0, -)、Slight (1, +)、Mild (2, ++)、Moderate (3, +++)、Severe (4, ++++)

Pathological score 3.3±0.5 2.4±0.4

Product Biowater AstaxanthinCapsule (500mg/ Capsule)

Predicate (500mg/ Capsule)

Dosage in rate (mg/kg) Low Dosage High Dosage Low Dosage High Dosage

100 200 200 1,000

Dosage equivalence to human (mg/60kg)

1,000(2 Cap)

2,000(4 Cap)

2,000(4 Cap)

10,000(20 Cap)

ALT(GPT) Decrease (%) 47.0 54.3 29.3 39.6

AST(GOT)Decrease (%) 49.4 55.2 41.9 45.8

liver fibrosis pathological improvement

1.2±0.4 1.3±0.5 1.2±0.1 1.4±0.2

Source: TFDA Food Safety Abstract/M62-150400008001

Industrial benefits/ Value-added

applications

32

Safety, efficacy, stability testing and formulation development completed

Astaxanthin HealthSupplement Launch to Market

Class 3 Health Supplement Registration

The new plant was officially opened; raw material extraction, purification and application development were completed; ahead of other raw material competitors.

expecting to increase turnover substantially, add 30 new employees, launch 3 now products, and apply for 2 new patents

Completed the first track case review for liver protection in health food certificate third category. Product can label its efficacy.

FINANCIAL HIGHLIGHTS• Consolidated Statement Unit: Thousand Dollar

33

Year 2015 2016 2017 2018 2019Q3

Revenue 452,640 477,330 476,395 519,550 397,489

Margin 162,863 140,581 114,907 126,310 115,127

Operating Profit 55,731 17,726 4,953 2,153 1,348

Net Income before tax 40,270 9,480 (40,133) 31,487 12,745

EPS 0.56 0.16 (0.68) 0.53 0.26

Gross Profit Margin 35.98% 29.45% 24.12% 24.31% 28.96%

Operating Profit Margin 12.31% 3.71% 1.04% 0.41% 0.34%

Net Profit Margin 8.90% 1.99% -8.42% 6.06% 3.21%

Sales Breakdown by Region

34

50%

60%

70%

80%

90%

100%

2015 2016 2017 2018 2019Q3

88% 87% 87% 85% 84%

12% 13% 13% 15% 16%

Other

Taiwan

Sales Breakdown by Product

35

50%

60%

70%

80%

90%

100%

2015 2016 2017 2018 2019Q3

96% 95% 95% 93%85%

4% 5% 5% 7%15%

0% 0% 0% 0% 0%

其他

保養品

醫療檢測產品

otherCare productsMedical testing products

Dividend Policy

36

Year 2013 2014 2015 2016 2017 2018

EPS 2.19 0.66 0.56 0.16 (0.68) 0.53

Cash DPS 0 1 0.51 1 0 0.5

Stock DPS 1.5 0 0 0 0.5 0

DividendPayout Ratio

68.49%151.52% 91.07%625.00% -73.53% 94.34%

Q & A37

AN INDUSTRY THAT CREATES HEALTHY, BEAUTIFUL AND ENVIRONMENTAL FRIENDLY PRODUCTBIOPTIK TECHNOLOGY, INC.

38

Thank you for listening~

BiOPTiK TECHNOLOGY, INC.AgendaCorporate IntroductionOrganization ChartQuality System投影片編號 6Headquarter Medical Device and Medical In Vitro Diagnostic DeviceHighlights – IoT ApplicationsDeveloping projects with external companiesHeadquarter Forecast投影片編號 11投影片編號 12投影片編號 13投影片編號 14投影片編號 15投影片編號 16Hsinchu Science Park Branch �Skin Care Products, Food Supplements, and Wound therapy productsHsinchu Science Park Branch�Food SupplementsDietary Supplement –Infomercial –PSAC astaxanthin capsuleDietary Supplement –Infomercial –Action FreeDietary Supplement – Physical ChannelHsinchu Science Park Branch ForecastHsinchu Science Park Branch Outlook�2020 Functional Product DevelopmentSubsidiary BIORED Natural Astaxanthin投影片編號 25投影片編號 26In Vivo Effects of Astaxanthin投影片編號 28投影片編號 29投影片編號 30投影片編號 31投影片編號 32Financial Highlights投影片編號 34投影片編號 35投影片編號 36投影片編號 37An industry that creates healthy, beautiful and environmental friendly product