biology worksheet...b) explain monohybrid cross. c) state mendel’s first law (law of segregation)....

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DB014 1 I KMPk CHAPTER 4: GENETIC INHERITANCE SUBTOPIC: 4.1 Mendelian genetics: Monohybrid and Dihybrid LEARNING OUTCOMES: a) State the terminologies used in genetic inheritance: allele, gene, locus, genotype, phenotype, homozygous, heterozygous, dominant, recessive, self-cross and test cross. b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio (1:2:1) and phenotypic ratio (3:1) of F2 generation. e) Show genetic diagram on the monohybrid test cross and include the genotypic ratio (1:1) and phenotypic ratio (1:1) of F2 generation f) Explain dihybrid cross. g) State Mendel’s second law (Law of Independent Assortment). h) Show genetic diagram on the dihybrid cross and include only phenotypic ratio (9:3:3:1) of F2 generation using Punnett square. i) Show genetic diagram on the dihybrid test cross and include the genotypic ratio (1:1:1:1) and phenotypic ratio (1:1:1:1) of F2 generation using Punnet square. 1. Match the vocabulary word with the proper definition. Vocabulary Definition 1 Allele involves the breeding of an individual with a phenotypically recessive individual, 2 Gene masks the recessive allele; an organism with a dominant allele will exhibit that form of the trait; represented by a capital letter 3 Locus the genetic constitution of a individual; genetic makeup 4 Genotype sequence of DNA that codes for a protein and determines a trait 5 phenotype term used to refer to an organism that has two different alleles for the same trait 6 homozygous any location on a chromosome, or any region of genomic DNA 7 heterozygous term used to refer to an organism that has two identical alleles for a particular trait 8 Dominant A cross between male and female from the same plants/generation 9 recessive describes the total physical appearance of an organism; physical characteristics 10 Self pollination one of a number of different forms of a gene BIOLOGY WORKSHEET

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Page 1: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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CHAPTER 4: GENETIC INHERITANCE

SUBTOPIC: 4.1 Mendelian genetics: Monohybrid and Dihybrid

LEARNING OUTCOMES:

a) State the terminologies used in genetic inheritance: allele, gene, locus, genotype,

phenotype, homozygous, heterozygous, dominant, recessive, self-cross and test cross.

b) Explain monohybrid cross.

c) State Mendel’s first law (Law of Segregation).

d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

(1:2:1) and phenotypic ratio (3:1) of F2 generation.

e) Show genetic diagram on the monohybrid test cross and include the genotypic ratio

(1:1) and phenotypic ratio (1:1) of F2 generation

f) Explain dihybrid cross.

g) State Mendel’s second law (Law of Independent Assortment).

h) Show genetic diagram on the dihybrid cross and include only phenotypic ratio

(9:3:3:1) of F2 generation using Punnett square.

i) Show genetic diagram on the dihybrid test cross and include the genotypic ratio

(1:1:1:1) and phenotypic ratio (1:1:1:1) of F2 generation using Punnet square.

1. Match the vocabulary word with the proper definition.

Vocabulary

Definition

1 Allele involves the breeding of an individual with a

phenotypically recessive individual,

2 Gene masks the recessive allele; an organism with a

dominant allele will exhibit that form of the trait;

represented by a capital letter

3 Locus the genetic constitution of a individual; genetic

makeup

4 Genotype sequence of DNA that codes for a protein and

determines a trait

5 phenotype term used to refer to an organism that has two

different alleles for the same trait

6 homozygous any location on a chromosome, or any region of

genomic DNA

7 heterozygous term used to refer to an organism that has two

identical alleles for a particular trait

8 Dominant A cross between male and female from the same

plants/generation

9 recessive describes the total physical appearance of an

organism; physical characteristics

10 Self pollination

one of a number of different forms of a gene

BIOLOGY WORKSHEET

Page 2: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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11 test cross masked by the dominant allele; organisms will only

exhibit this form of the trait if the dominant allele is

not present; represented by a lower case letter

2. Multiple Choice: Circle the letter of the correct choice.

Mendel’s First Set of Experiments

At first, Mendel experimented with just one characteristic at a time. He began with flower colour. As

shown in the figure below, Mendel cross-pollinated purple- and white-flowered parent plants. The parent

plants in the experiments are referred to as the P (for parent) generation.

This diagram shows Mendel’s first experiment with pea plants. The F1 generation results from cross-

pollination of two parent (P) plants. The F2 generation results from self-pollination of F1 plants.

F1 and F2 Generations

The offspring of the P generation are called the F1 (for filial, or “offspring”) generation. As you can see

from the figure above, all of the plants in the F1 generation had purple flowers. None of them had white

flowers. Mendel wondered what had happened to the white-flower characteristic. He assumed some type

of inherited factor produces white flowers and some other inherited factor produces purple flowers. Did

the white-flower factor just disappear in the F1 generation? If so, then the offspring of the F1 generation

— called the F2 generation — should all have purple flowers like their parents.

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To test this prediction, Mendel allowed the F1 generation plants to self-pollinate. He was surprised by the

results. Some of the F2 generation plants had white flowers. He studied hundreds of F2 generation plants,

and for every three purple-flowered plants, there was an average of one white-flowered plant.

Law of Segregation

Mendel did the same experiment for all seven characteristics. In each case, one value of the characteristic

disappeared in the F1 plants and then showed up again in the F2 plants. And in each case, 75 percent of F2

plants had one value of the characteristic and 25 percent had the other value. Based on these observations,

Mendel formulated his first law of inheritance. This law is called the law of segregation. It states that

there are two factors controlling a given characteristic, one of which dominates the other, and these

factors separate and go to different gametes when a parent reproduces.

1.Why did Mendel choose to work with the garden pea plant?

a. Because the pea plant is easy to work with.

b. Because pea plants are fast growing.

c. Because the pea plant has a number of characteristics, each with only two forms.

d. all of the above

2.In Mendel's first experiment

a. the F1 displayed all purple-flowered plants.

b. the F1 displayed all white-flowered plants.

c. the F2 displayed all purple-flowered plants.

d. the F2 displayed half purple-flowered and half white-flowered plants.

3.The law of independent assortment states that

a. two factors of the same characteristic separate into different gametes.

b. there are dominant and recessive factors.

c. factors controlling different characteristics are inherited independently of each other.

d. there are two factors that control inheritance.

4.Looking at your cat will give information concerning

a. the cat's genotype.

b. the cat's phenotype.

c. the cat's recessive alleles.

d. the cat's heterozygous alleles.

5.Which sentence is correct?

a. Different alleles of the same gene are located at the same locus on different homologous

chromosomes.

b. Different alleles of the same gene are located at different loci on different homologous

chromosomes.

c. Different genes of the same alleles are located at the same locus on different homologous

chromosomes.

d. Different alleles of the same gene are located at different loci on the same chromosome.

Page 4: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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6.An Aa individual

a. has a homozygous genotype.

b. has a heterozygous phenotype.

c. has a heterozygous genotype.

d. has a homozygous phenotype.

7.In Mendel's initial experiments, an example of the F2 generation would be

a. 75 round seed plants to 25 wrinkled seed plants

b. 75 green seed plants to 25 yellow seed plants

c. 75 white-flowered plants to 25 purple-flowered plants

d. all of the above

8.Which of the following is part of the law of segregation?

(1) there are two factors controlling a given characteristic,

(2) one factor is dominant over the other factor,

(3) the two factors separate into different gametes.

a. 1 and 2

b. 1 and 3

c. 2 and 3

d. 1, 2, and 3

3. Set up the Punnett squares for each of the crosses listed below. Round seeds are dominant to

wrinkled seeds.

(a) RR x rr

What percentage of the offspring will be round?

(b) Rr x rr

What percent of the offspring will be round?

(c) RR x Rr

What percent of the offspring will be round?

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(d) Rr x Rr

What percent of the offspring will be round?

(e) From (a), (b), (c), and (d), which one produces genotypic ratio (1:2:1) and phenotypic

ratio (3:1)?

4. In Mendel’s experiment, true-breeding pea plants with spherical seeds were crossed with true-

breeding plants with dented seeds. Mendel collected the seeds from this cross, grew F1 generation

plants, let them pollinate to form a second generation, and analysed the seeds of the resulting F2

generation.

a) State the Law of Segregation.

___________________________________________________________________________

___________________________________________________________________________

b) Suggest symbols for the seed shape and show a genetic diagram to explain the genotypic and

phenotypic ratio you would expect if the F1 generation sere self-pollinate.

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5. A male and female bird has 4 un-hatched eggs. The female on the left is heterozygous; the male

on the right is homozygous recessive. Use G or g for your genotypes.

(a) Write the genotype of the female (left): _________________________________

(b) Write the genotype of the male (right): __________________________________

(c) Which colour is dominant, grey or black? How do you know?

___________________________________________________________________

___________________________________________________________________

(d) Write the phenotype of the female and the phenotype of the male below:

___________________________________________________________________

___________________________________________________________________

(e) Complete the Punnett square below for this couple:

(f) What is the predicted genotypic ratio of the offspring?

___________________________________________________________________

(g) What will be the colour of the baby birds?

___________________________________________________________________

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6. Dihybrid crosses examine two unlinked (on different chromosomes) gene loci. The following

problem uses many of the skills you learned in the section on monohybrid crosses.

In peas, a single gene codes for stem length and another single gene codes for seed shape. Each

gene has two alleles, one dominant and one recessive. For stem length, tall plants are dominant

over short plants. For seed shape, smooth peas are dominant over wrinkled peas.

A. Choose letters to represent each gene and its alleles.

Seed shape: Smooth:_____ wrinkled:_____

Stem length: Tall:______ short:______

B. In Table 4.1 is a list of all the possible phenotypes for this pair of traits. Determine the

genotypes for these plants, in some cases there will be multiple possible genotypes. When we

worked with one gene locus, each individual genotype was represented by 2 letters since

individual organisms are diploid. Now we are working with two gene loci, so each individual

genotype will be represented by 4 letters, 2 letters for each gene locus. The first genotype is

given.

C. For each of the individuals in part B, list all the unique gametes that can be produced.

Remember, each gamete will have 1 allele from each gene locus. When we worked with a single

gene, each gamete genotype was represented by 1 letter. Now we are working with 2 gene loci, so

each gamete genotype will be represented by 2 letters, one from each gene locus. Fill in the rest

of the Table with all the possible gamete genotypes for each parent genotype listed. The first

gamete genotype is given.

TABLE 4.1 Table of Genotypes for Two Loci

Phenotype Possible genotype Possible gametes

SMOOTH, TALL SSTT ST

wrinkle, TALL

SMOOTH, short

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wrinkle, short

(a) Determine the F1 genotypes and phenotypes resulting from a cross of a homozygous smooth and

homozygous tall plant with a wrinkled, short plant.

(b) What are the F2 genotypes and phenotypes (crossing two F1)

7. In pea plants, green pod colour is dominant over yellow pod colour. Tall plant height is dominant

over short plant height.

(a) A tall green pea plant (TTGG) is crossed with a short white pea plant (ttgg).

TT or Tt = tall tt = short GG or Gg = green gg = white

Parental Generation genotypes: ___________ x ___________

Possible gametes: ___________________________________

Phenotypic Ratio: ___ tall/green : ___ tall/yellow : ___ short/green : ___short/ yellow

Genotypic Ratio: _______________________________________________________

(b) A tall green pea plant (TtGg) is crossed with a Short white pea plant (ttgg).

Parental Generation genotypes: ___________ x ___________

Possible gametes: ___________________________________

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Phenotypic Ratio: ___ tall/green : ___ tall/yellow : ___ short/green : ___short/ yellow

Genotypic Ratio: _______________________________________________________

(c) Two heterozygous tall, green pea plants are crossed.

Parental Generation genotypes: ___________ x ___________

Possible gametes: ___________________________________

Phenotypic Ratio: ___ tall/green : ___ tall/yellow : ___ short/green : ___short/ yellow

Genotypic Ratio: _______________________________________________________

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8. Set up a Punnett square using the following information:

Dominant allele for black fur in guinea pigs = B

Recessive allele for white fur in guinea pigs = b

Dominant allele for rough fur in guinea pigs = R

Recessive allele for smooth fur in guinea pigs = r

Cross a heterozygous parent (BbRr) with a heterozygous parent (BbRr).

a. What is the probability of producing guinea pigs with black, rough fur? Possible genotype(s)?

____________________________________________________________________________

b. What is the probability of producing guinea pigs with black, smooth fur?

Possible genotype(s)?

____________________________________________________________________________

c. What is the probability of producing guinea pigs with white, rough fur?

Possible genotype(s)?

____________________________________________________________________________

d. What is the probability of producing guinea pigs with white, smooth fur? Possible genotype(s)?

____________________________________________________________________________

9. State Mendel’s Second Law. Under what conditions are these laws applicable?

____________________________________________________________________________

____________________________________________________________________________

____________________________________________________________________________

____________________________________________________________________________

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10. In rats, short fur is controlled by dominant allele (A) while long fur is controlled by

recessive allele (a). Black fur is controlled by allele (B) and brown fur by allele (b). The

two genes concerned are located on different chromosomes. A cross is made between a

female rat and a male rat. What are the expected parental genotypes if the phenotypic

ratio in F2 generation is 9 short,black : 3 short,brown : 3 long, black : 1 long, brown.

Show a genetic diagram to proof your answer.

Page 12: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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SUBTOPIC: 4.2 Deviations from the Mendelian inheritance

LEARNING OUTCOMES:

a) Define and give example of the following

-codominant (MN blood group)

-incomplete dominant (Antirrhinum sp.)

-multiple allele (human ABO blood group)

-polygene (human skin color)

-linked gene (wing size and body color of Drosophila sp.)

-sex-linked gene (haemophilia)

Complete table below:

Description Types of inheritance that

deviate from Mendelian

Examples

Both alleles of a pair are fully

expressed in a heterozygote

Codominant alleles

Incomplete dominant

alleles

Colour of snapdragon flower

Antirrhinum majus

More than two alleles control

for particular trait of a

character

Multiple alleles

Linked genes

Genes that are carried by

either sex chromosomes (X

and Y)

Sex-linked genes

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Polygenes

Skin colour

Codominant alleles

1. The alleles governing the MN blood group system in man are codominant and

may be represented by the symbols LM and LN.

Genotype Blood group (phenotype)

LMLM M

LMLN MN

LNLN N

Use the genetic diagram to show the expected phenotypic ratio for the crosses

between two heterozygous individuals.

2. Human blood types are determined by genes that follow the CODOMINANT pattern of

inheritance. There are two dominant alleles (IA and IB) and one recessive allele (i).

Blood Type

(Phenotype)

Genotype Can donate blood to: Can receive blood from:

O

ii

A,B,AB and O

(universal donor)

O

AB

IAIB

AB

A,B,AB and O

(universal receiver)

Page 14: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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A

IAIA or IAi

AB, A

O,A

B

IBIB or IAi

AB,B

O,B

(a) Write the genotype for each person based on the description:

a. Homozygous for the “B” allele : _______________________________________

b. Heterozygous for the “A” allele : _______________________________________

c. Type O : __________________________________________________________

d. Type “A” and had a type “O” parent : ___________________________________

e. Type “AB” : _______________________________________________________

f. Blood can be donated to anybody : _____________________________________

g. Can only get blood from a type “O” donor : ______________________________

(b) Pretend that Brad Pitt is homozygous for the type B allele, and Angelina Jolie is type

“O.” What are all the possible blood types of their baby?

(c) Draw a Punnett square showing all the possible blood types for the offspring produced by

a type “O” mother and an a Type “AB” father.

Page 15: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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Incomplete dominant alleles

1. Snapdragon are incomplete dominant for colour, they have phenotypes red, pink and

white. The red and white flowers are homozygous, and the pink flowers are

heterozygous. Give the genotypes for each of the phenotypes, using the letters “R” and

“W” for alleles:

a. Red snapdragon : ___________________________________________________

b. Pink snapdragon : ___________________________________________________

c. White snapdragon :__________________________________________________

2. Show genetic crosses between the following snapdragon parents, using the punnett

squares provided, and record the genotypic and phenotypic ratios below:

a. Pink x Pink

% Red snapdragon : _____________________________

% Pink snapdragon : _____________________________

% White snapdragon : ___________________________

Genotypic ratio : ________________________________

Phenotypic ratio: _______________________________

b. Red x White

% Red snapdragon : _____________________________

% Pink snapdragon : _____________________________

% White snapdragon :___________________________

Genotypic ratio : ________________________________

Phenotypic ratio: _______________________________

gametes

gametes

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c. Pink x White

% Red snapdragon : _____________________________

% Pink snapdragon : _____________________________

% White snapdragon : ___________________________

Genotypic ratio : ________________________________

Phenotypic ratio: _______________________________

3. The shapes and colours in carrots are determined by two pairs of different alleles. Both

pairs of alleles did not show dominancy. Each genotype produces different phenotypes.

Colours of carrots are red (CRCR), purple (CRCW) or white (CWCW). The shapes are long

(SLSL), oval (SLSN) or round (SNSN).

(a) What type of inheritance is shown by the shape and colours of carrot? [1 mark]

__________________________________________________________________

(b) The long, red carrot is crossed with the round, white carrot. With a genetic

diagram, show the parent genotypes, gametes and F1 generation. [3 marks]

gametes

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(c) If the F1 generation is self-crossed, what are the frequencies for the following

phenotypes? [4 marks]

Phenotypes Frequency

Red, oval

Purple, long

White, long

White, round

(d) If the purple, oval carrot has the highest demand in the market, give TWO

possible crosses that can be done to meet the demand. [2 marks]

__________________________________________________________________

__________________________________________________________________

4. With the aid of genetic diagram, explain incomplete dominance and its inheritance in

snapdragon (Antirrhinum sp.) [12 marks]

Page 18: BIOLOGY WORKSHEET...b) Explain monohybrid cross. c) State Mendel’s first law (Law of Segregation). d) Show genetic diagram on the monohybrid cross and include the genotypic ratio

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Multiple alleles

1. Human blood types are determined by genes with multiple alleles. Each person can have

two of the four possible alleles. These alleles will specify if there is a type of molecule on

the surface of blood cells (A, B, AB) or none (O).

Blood type

(Phenotype)

Genotype Can donate blood to Can receive blood from

O ii A, B, AB and O

(Universal donor)

O

AB IAIB AB A, B, AB and O

(Universal receiver)

A IAIA

IAi

AB, A O, A

B IBIB

IBi

AB, B O, B

(a) Draw a Punnett square showing all the possible blood types for the offspring produced by

a type “O” mother and an a type “AB” father. Draw genetic diagram and record the

genotypic and phenotypic ratios

P phenotype :

P genotype :

Gamete :

F1 generation :

Genotypic ratio :

Phenotypic ratio :

gametes

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(b). Two parents think their baby switched at the hospital. It’s 1968, so DNA fingerprinting

technology does not exist yet. The mother has blood type “O”, the father has blood type

“AB” and the baby has blood type “B”.

a. Mother’s genotype :_______________________________________________

b. Father’s genotype :_______________________________________________

c. Baby’s genotype :_______________________________________________

d. Punnett square showing all possible genotypes for children produced by this

couple:

e. Draw genetic diagram for the above cross.

P phenotype :

P genotype :

Gamete :

F1 generation :

Genotypic ratio :

Phenotypic ratio :

f. Was the baby switched?

__________________________________________________________________

gametes

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2. The ABO blood group system in human is an example of interactions of alleles that

are illustrated by multiple alleles.

(a) What is meant by multiple alleles? [2 marks]

____________________________________________________________________

____________________________________________________________________

(b) State the alleles that control the ABO blood group system in humans. [1 mark]

____________________________________________________________________

(c) State the likely allele combinations in ABO blood group system. [3 marks]

____________________________________________________________________

____________________________________________________________________

(d) The table below shows three husband and wife couples with their respective blood

groups and their percentage of the number of children produced in accordance with

blood groups. State the parents’ genotype for each of the crossed couples in the table

below. [3 marks]

Couple Parents’

blood

Percentage of number of

children in accordance with

blood group

Parents’ genotype

A

B AB O

First O X A 50 - - 50

Second B X A 25 25 25 25

Third A X AB 50 25 25 -

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Linked genes

1. In pea, the gene for green seed (G), and smooth seed (S), are dominant over the

genes for yellow seed and wrinkled seed. Pure breeding strains of the dominant and

recessive varieties were crossed. A test cross of the F1 generation produced the following

results:

Green seed, smooth seed 180

Yellow seed, wrinkled seed 193

Green seed, wrinkled seed 7

Yellow seed, smooth seed 6

(a) (i) Does the above cross follow the Mendelian ratio? [1 mark]

__________________________________________________________________

(ii) Explain how the situation in (a)(i) occurs. [2 marks]

__________________________________________________________________

__________________________________________________________________

(b) Draw the genetic diagram for the test cross of F1 generation. [4 marks]

(c) Calculate the distance between the two genes. Show your calculation. [3 marks]

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3. Black coloured body and vestigial wings in Drosphila sp. are controlled by two recessive

alleles b and vg. Dominant alleles, b+ and vg+ produce wild type (grey coloured body

and normal wings). A homozygous wild type is crossed to a homozygous black coloured

body and vestigial wings. The F1 progenies produced are all of wild type and are crossed

with homozygous recessive. The F2 generations are as follows:

442 wild type : 458 black, vestigial : 46 black, normal : 54 grey,vestigial

(a) Using genetic diagram, explain the results shown above. [6 marks]

(b) Calculate the distance between the genes controlling the body colour and the type of

wing. [2 marks]

(c) If the genes are not linked, what is the expected number of individuals of each

phenotype in the F2 generation? [2 marks]

_____________________________________________________________________

_____________________________________________________________________

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Sex-linked genes

1. In fruit flies, eye color is a sex linked trait. Red is dominant to white.

(a) What are the sexes and eye colors of flies with the following genotypes:

X R X r _______________ X R Y _______________

X R X R _______________ X r Y _______________

(b) What are the genotypes of these flies:

white eyed, male ______________ red eyed female (heterozygous) _______________

white eyed, female ______________ red eyed, male _______________

(c) Show the cross of a white eyed female X r X r with a red-eyed male X R

Y .

(d) Show a cross between a pure red eyed female and a white eyed male.

i) What are the genotypes of the parents:

__________________________________________________________________

ii) How many are:

white eyed, male _______________

white eyed, female _______________

red eyed, male _______________

red eyed, female _______________

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(e) Show the cross of a red eyed female (heterozygous) and a red eyed male.

i) What are the genotypes of the parents?

__________________________________________________________________

ii) How many are:

white eyed, male_______________

white eyed, female _______________

iii) What if in the above cross, 100 males were produced and 200 females. How

many total red-eyed flies would there be?

red eyed, male _______________

red eyed, female _______________

2. In humans, hemophilia is a sex linked trait. Females can be normal, carriers, or have the

disease. Males will either have the disease or not (but they won’t ever be carriers)

= female, normal

= female, carrier

= female, hemophiliac

= male, normal

= male, hemophiliac

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(a) Show the cross of a man who has hemophilia with a woman who is a carrier. What is the

probability that their children will have the disease?

(b) A woman who is a carrier marries a normal man. Show the cross. What is the

probability that their children will have hemophilia? What sex will a child in the

family with Hemophilia be?

(c) A woman who has hemophilia marries a normal man. How many of their children will have

hemophilia, and what is their sex?

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TEST TOUR SELF

Multiple Choice Questions

1. Mendel crossed pure breeding plants having smooth seeds with pure breeding plants

having wrinkled seeds. The F1 plants had smooth seeds. Then the F1 plants were allowed

to self-fertilize. Mendel collected 600 F2 plants. How many of these would be expected

to have smooth seeds and how many wrinkled seeds?

A. 400 smooth seeds and 200 wrinkled seeds

B. 300 smooth seeds and 300 wrinkled seeds

C. 450 smooth seeds and 150 wrinkled seeds

D. 150 smooth seeds and 450 wrinkled seeds

2. A genetic cross between an individual showing a dominant phenotype (unknown

genotype) and a homozygous recessive individual is known as a_________________

A. back cross

B. reciprocal cross

C. self-cross

D. test cross

3. Which of the following is (are) TRUE for allele

A. They can be identical or different for any given gene in a somatic cell

B. They can be dominant or recessive

C. They can represent alternative forms of a gene

D. All of the above

4. A genetic cross of two plants results in offspring with 9:3:3:1 ratio for a particular trait.

This condition shows ______________

A. the genes controlling the traits were located on same chromosome

B. multiple allele

C. that both parents were heterozygous

D. monohybrid cross

5. How many unique gametes could be produced through independent assortment by an

individual with the genotype RrSsTTUu?

A. 4

B. 8

C. 16

D. 32

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6. A pointed contour off the hairline on the forehead or known as widow’s peak is dominant

to straight hairline in human. A woman with widow’s peak married a man with straight

hairline. They had a daughter with widow’s peak which later also married to a man with

straight hairline. What is the percentage of their first child having widow’s peak?

A. 100%

B. 70%

C. 50%

D. 25%

7. A cross between two true-breeding pea plants were done in which one parent has purple,

axial flowers and other has white, terminal flowers. All the F1 progenies have purple,

axial flowers. The F1 progenies were self-crossed and produced 1500 F2 offsprings.

Approximately how many of them would you expect to have white flowers with axial

position?

A. 90

B. 280

C. 560

D. 850

8. The term ‘true-breeding’ refers to

A. Organism that are homozygous for all traits

B. Organisms that come from genetically pure lines

C. Organisms that will produce offspring with the same characteristics as the parents

D. Organisms that have a high rate of reproduction

9. A plant with purple flowers is allowed to self-pollinate. Generations after generations, it

produces purple flowers. This is an example of

A. Hybridization

B. Incomplete dominance

C. True-breeding

D. Polygenes

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10. In humans, brown eyes are dominant to blue eyes. A marriage between two brown.eyed

individuals produces a child with blue-eyes. This indicates that

A. The possibility that their second child will have brown eyes is ¼

B. The possibility that their second child will have blue eyes is ½

C. Both parents are homozygous for brown eyes

D. Both parents are heterozygous for eye colour

11. In the F2 generation of a dihybrid cross between yellow, round seed pea plants and green,

wrinkled seed pea plants, 35 out of 496 pea seeds were green and wrinkled. Other seeds

were yellow and round , green and round, yellow and wrinkled. These results show that

A. The alleles for green and wrinkled are linked

B. Crossing over has occurred

C. Green and wrinkled are both recessive characteristics

D. The allele for green is recessive but not the allele for wrinkled

12. Two plants are crossed, resulting in offspring with a 3:1 phenotypic ratio for a particular

trait. This suggest

A. That the parents were true-breeding for contrasting traits

B. Incomplete dominance

C. That are blending of traits has occurred

D. That the parents were both heterozygous

13. Two characters that appear in a 9:3:3:1 ratio in the F2 generation should have which of

the following properties?

A. Each of the characters is controlled by a single gene

B. The genes controlling the characters obey the Law Of Independent Assortment

C. Each of the genes controlling the characters has two alleles

D. A, B and C are correct

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14. Black fur in mice (B) is dominant to brown fur (b). Short tails (T) are dominant to long

tails (t). What fraction of the progeny of the cross BbTt x BBtt will have black fur and

long tails?

A. 1/16

B. 1/2

C. 3/16

D. 3/8

15. A sexually reproducing animal has two unlinked genes, one for head shape (H) and one

for tail length (T). Its genotype is HhTt. Which of the following genotypes is possible in a

gamete from this organism?

A. HT

B. Hh

C. HhTt

D. tt

16. Which of the following is FALSE, regarding the Law of Segregation?

A. It states that each of two alleles for a given trait segregate into different gametes.

B. It can be explained by the segregation of homologous chromosomes during meiosis

C. It is a method that can be used to determine the number of chromosomes in a plant.

D. It can be used to predict the likelihood of transmission of certain genetic diseases

within families.

17. A couple has three children, all of whom have brown eyes and blond hair. Both parents

are homozygous for brown eyes (BB), but one is a blond (rr) and the other is a redhead

(Rr). What is the probability that their next child will be a brown-eyed redhead?

A. 1/16

B. 1/4

C. 1/8

D. 1/2

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18. An advantage that made Mendel’s experiment successful is

A. He used true breeding members of plants for mating

B. His plants had many phenotypes for a trait

C. His plants required many years to develop

D. He used mathematical laws to interpret his results

19. Two organisms with genotype TtGg mate. The chance of producing an offspring that has

the dominant phenotype for height and recessive phenotype for colour is

A. 9/16

B. 7/16

C. 6/16

D. 3/16

20. Two different phenotypes result among the offspring from a genetic cross. The genotypes

of the parents should be

A. TT and TT

B. TT and Tt

C. Tt and tt

D. tt and tt